ライフサイエンスコーパス: dopachrome tautomerase

1 on of an early zebrafish melanoblast marker, dopachrome tautomerase.

2 melanocytes, Tyr, Tyr-related protein 1, and dopachrome tautomerase accumulated in enlarged granules

3 also has been described recently to exhibit dopachrome tautomerase activity and to be structurally h

4 yphenylalanine oxidation drop rapidly, while DOPAchrome tautomerase activity increases and dihydroxyi

5 ne is the same as the catalytic site for the dopachrome tautomerase activity of MIF.

6 methyl ester (ISO-1), an inhibitor of MIF d-dopachrome tautomerase activity, reveals that ISO-1 bind

7 nd of the melanogenic enzymes tyrosinase and dopachrome tautomerase, all major players in melanogenes

8 and functional similarity, the MIF homolog D-dopachrome tautomerase (also called MIF-2) has low seque

9 r (MIF) protein family consists of MIF and D-dopachrome tautomerase (also known as MIF-2).

10 cy of an enhancer required for expression of dopachrome tautomerase, an enzyme that functions in mela

11 igens gp100 and tyrosinase-related protein 2/dopachrome tautomerase and increased protection from a l

12 cell development and pigmentation, including dopachrome tautomerase and tyrosinase.

13 as tyrosinase, tyrosinase-related protein-1, dopachrome tautomerase, and Pmel17, are known, the funct

14 rophthalmia-associated transcription factor, dopachrome tautomerase, and tyrosinase promoters, leadin

15 n inhibitory factor (MIF) and its paralog, D-dopachrome tautomerase, are multifunctional inflammatory

16 hage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT or MIF2) play key roles in

17 tic understanding of the MIF homolog MIF-2/d-dopachrome tautomerase (d-DT) and its clinical translati

18 be the protein encoded by the homologous, D-dopachrome tautomerase (D-DT) gene.

19 ally functionally redundant family member, D-dopachrome tautomerase (D-DT), also remains to be furthe

20 ation inhibitory factor (MIF), its homolog D-dopachrome tautomerase (D-DT), and their common receptor

21 y factor (MIF) and its functional homolog, d-dopachrome tautomerase (d-DT), have protumorigenic funct

22 rine MIF and its only known family member, D-dopachrome tautomerase (D-DT), promote the expression of

23 For the immunomodulatory protein D-dopachrome tautomerase (D-DT), the mechanism of protein-

24 ew inflammatory activity for extracellular d-dopachrome tautomerase (D-DT), the recruitment of neutro

25 Plant MIF/D-dopachrome tautomerase (D-DT)-like proteins (MDLs) can i

26 droxyphenylpyruvate dioxygenase (HPPD) and D-dopachrome tautomerase (D-DT); two additional enzymes th

27 iption of a second MIF superfamily member, D-dopachrome tautomerase (D-DT/MIF-2), prompted closer inv

28 Tyrosinase and dopachrome tautomerase (DCT) activities were found exclu

29 DOPAchrome tautomerase (Dct) functions downstream of tyr

30 The melanin synthesis enzyme dopachrome tautomerase (DCT) is involved in intracellula

31 carrying a tyrosinase minigene driven by the dopachrome tautomerase (Dct) promoter region.

32 cell development in transgenic mice from the dopachrome tautomerase (Dct) promoter.

33 inase, tyrosinase-related protein-1 (Tyrp1), dopachrome tautomerase (Dct), and LAMP1 and 3 localizati

34 essing neural precursor cells (line Ntva) or dopachrome tautomerase (DCT)-expressing melanoblasts (li

35 yrosinase-related protein-1 (TYRP1/gp75) and dopachrome tautomerase (DCT/TYRP2) belong to a family of

36 pression of members of the MIF family MIF, D-Dopachrome Tautomerase (DDT) and DDT-like (DDTL) in a lu

37 Recent work by others has described D-dopachrome tautomerase (DDT) as a functional homologue o

38 D-dopachrome tautomerase (DDT) is an enzyme that lacks phy

39 of the role of MIF (and its family member D-dopachrome tautomerase (DDT)) in genitourinary cancers a

40 The expression of the dopachrome tautomerase gene (Dct) and its protein produc

41 lite resident within an intron of the bovine dopachrome tautomerase gene.

42 tion genes, tyrosinase-related protein 1 and Dopachrome-tautomerase have lower protein levels in NPC1

43 s and for physiological investigations (e.g. dopachrome tautomerase in melanogenesis).

44 ge migration inhibitory factor-2 (MIF-2 or D-dopachrome tautomerase) is a recently characterized seco

45 l-Dopachrome tautomerase (l-DCT), also called tyrosinase-r

46 Plants have orthologous MIF and D-dopachrome tautomerase-like (MDL) proteins that mimic so

47 racterized three MIF orthologs (termed MIF/d-dopachrome tautomerase-like proteins or MDLs) of the mod

48 We identify D-dopachrome tautomerase/macrophage migration-inhibitory f

49 osinase or on the mRNA levels of tyrosinase, dopachrome tautomerase, Pmel17, or MITF mRNA levels.

50 nder the regulation of a melanocyte-specific dopachrome tautomerase promoter.

51 enic line with Grm1 expression driven by the dopachrome tautomerase promoter.

52 (HO)2IndCOOH from dopachrome is catalyzed by dopachrome tautomerase, that the melanogenic protein tyr

53 yrosinase, melanocortin receptor (MC1R), and dopachrome tautomerase (TRP-2).

54 tyrosinase, tyrosinase-related protein-1 and dopachrome tautomerase/tyrosinase-related protein-2 and