ライフサイエンスコーパス: duct

1 ucture on the luminal side of the collecting duct.

2 racteristics of precancerous lesions of bile duct.

3 were concurrently measured from the exhaust duct.

4 d female diabetic Balb/c mice via pancreatic duct.

5 l (ENaC) activity in the cortical collecting duct.

6 mors arising in the pancreas and distal bile duct.

7 s connecting to lymph nodes and the thoracic duct.

8 e to < 75% of the diameter of the unaffected duct.

9 is specifically expressed in the collecting duct.

10 and traffic into the blood via the thoracic duct.

11 phoid tissues into blood, the human thoracic duct.

12 alignancy arising along the craniopharyngeal duct.

13 followed by being excreted in its excretory duct.

14 thelin 1 in the connecting tubule/collecting duct.

15 , including those arising from the Mullerian ducts.

16 ation to populate the proximal region of the ducts.

17 tified unusual intermitochondrial connecting ducts.

18 of the intrahepatic and/or extrahepatic bile ducts.

19 x2-EGFP(-)) from E12, E14.5 and E16 cochlear ducts.

20 al growth factor-1 compared to nonneoplastic ducts.

21 al cell fate selection within the collecting ducts.

22 e myxoid stroma with cystically dilated bile ducts.

23 f epithelial cells in the proximal prostatic ducts.

24 ents for repairing or replacing damaged bile ducts.

25 ation compared to nonneoplastic PSC-affected ducts.

26 gn lesions in intraluminal extrahepatic bile ducts.

27 ngitis due to regurgitation of BA from leaky ducts.

28 ance of both intra- and extrahepatic biliary ducts.

29 nocytes were found to be located around bile ducts.

30 nocytes were found to be located around bile ducts.

31 res three lateral cell clusters connected to ducts.

32 ikely due to undetected accessory pancreatic ducts.

33 e immunopathological characteristics of bile ducts.

34 copic duct-to-duct), number of graft biliary duct (=1 versus >1), number of biliary anastomosis (=1 v

35 bules, and the apical membrane of collecting duct A-type intercalated cells, and plays a crucial role

36 d sparse absorbers (two-port), and broadband duct absorbers (two-port).

37 enchymal cells (PMCs) that surround the bile duct after cholestatic and hepatocellular injury.

38 ate that slowing drug release in the mammary duct after intraductal administration overcomes the rapi

39 Interestingly, PI3Kalpha(H1047R) ducts also elicit increased permeability and structural

40 Pancreatic duct and endocrine lineages arise in a spatially distinc

41 ytic lesions that expanded outwards from the duct and endophytic lesions that grew inwards to the duc

42 f accurate localization of the leaking chyle duct and its repair by endosuturing in a renal donor not

43 epithelium resulted in a shortened cochlear duct and misoriented and misshapen hair bundles.

44 epithelial hyperplasia in proximal alveolar ducts and adjacent alveoli with associated centriacinar

45 nstrated reduced decorin surrounding mammary ducts and enhanced TGFbeta1 activity within mammary epit

46 testes, sperm agglutinations in the efferent ducts and lack of spermatozoa in the epididymis (azoospe

47 Breast ducts and lobules demonstrated increased decorin in the

48 ctions between progenitors of the collecting ducts and nephrons are primarily responsible for kidney

49 or types, one that originates from the sweat ducts and one that is based on thermal changes of the su

50 he absence of primary cilia compared to bile ducts and PBG cells in controls and patients with PSC.

51 totally absent (2/2, 50%) or rare (2/2, 50%) ducts and rare acinar zymogen granules (3/4, 75%).

52 usion of 120 mM (5%) STC into the pancreatic duct, and duct ligation.

53 azygos vein, right hepatic vein, common bile duct, and superior mesenteric artery.

54 onic pancreatitis, a dilated main pancreatic duct, and who only recently started using prescribed opi

55 increased number of islets, mainly close to ducts, and increased Sox9 and Ngn3 mRNA levels in islets

56 meibum led to the dilation of the meibomian ducts, and the progressive degeneration of the MGs.

57 In mice, fluconazole increased collecting duct AQP2 plasma membrane localization and reduced urina

58 Fluconazole promotes collecting duct AQP2 plasma membrane localization in the absence of

59 at Siglec-8 ligands in submucosal glands and ducts are normally transported to the airway mucus layer

60 The Mullerian ducts are the anlagen of the female reproductive tract,

61 The silk emerges from labial ducts as a nanofibrous fluid gel, flowing over the stone

62 developmental disorder characterized by bile duct (BD) paucity, caused primarily by haploinsufficienc

63 rized into main-duct (MD-IPMN) versus branch-duct (BD-IPMN).

64 d (n = 5, collected before surgery) and bile duct brushings (n = 2) were analyzed for translocations.

65 as in matched pancreatic cyst fluid and bile duct brushings.

66 from a rod of unpolarized cells into mature ducts by de novo lumen formation in a dynamic multi-step

67 , lung, ovarian, pancreatic, gastric or bile duct cancer and 245 healthy individuals.

68 Cholangiocarcinoma (CCA) is a bile duct cancer that originates in the bile duct epithelium.

69 Hepatocyte, fibrotic lesion, and bile duct (cancer) were classified and HCA mapping showed sim

70 Bile duct cannulation was successful in 23 patients (74.2%) i

71 for 0, 30, 60, 180, or 300 s after deep bile duct cannulation.

72 ts in TPS group had more frequent pancreatic duct cannulation.

73 Salivary duct carcinoma (SDC) is one of the most aggressive subty

74 In contrast, Yap/Taz deletion in adult bile ducts caused severe defects and delay in liver regenerat

75 The role of common bile duct (CBD) stenting in the establishment of bile stream

76 gions of the kidney, the cortical collecting duct (CCD) and the thick ascending loop of Henle (TALH).

77 pal cell function in the cortical collecting duct (CCD).

78 ed cells (alphaICs) in the kidney collecting duct (CD) belong to a family of mitochondria rich cells

79 ependent gene expression in renal collecting duct (CD).

80 dneys provides limited insight of collecting duct cell gene expression, because these cells comprise

81 is induced by high-salt levels in collecting duct cells and activates the Slc14a2 gene by recruiting

82 ents phosphoproteomic findings in collecting duct cells describing the response to V2R-selective vaso

83 Bile duct cells expressed the LPS receptor, Toll-like recepto

84 in PDACs and pancreatic cyst fluid and bile duct cells from the same patients.

85 Here, we use phosphoproteomics in collecting duct cells in which PKA has been deleted (CRISPR-Cas9) t

86 V2-receptor mediated signaling in collecting duct cells is in part PKA-independent.

87 to characterize periductal fibrosis and bile duct cells progressing to CCA induced by inoculating O.

88 While the progenitor and duct cells started to proliferate and expand at 72 hours

89 opressin through actions in renal collecting duct cells to regulate the water channel protein aquapor

90 , we used cultured mouse cortical collecting duct cells to see how overexpression or silencing of epi

91 fficking of polycystins in kidney collecting duct cells without affecting protein levels or cilia.

92 ficiently taken up by striated and excretory duct cells, and eventually secreted into saliva.

93 ls and spares immortalized normal pancreatic duct cells, hTERT-HPNE.

94 lpha) s-coupled receptor (V2R) in collecting duct cells, resulting in increased water permeability th

95 ecular markers separated presumptive bud and duct cells.

96 l target genes in inner medullary collecting duct cells.

97 functions of primary extra- or intrahepatic duct cholangiocytes within 2 weeks of isolation.

98 MCF7-derived ducts cocultured with obese stromal cells exhibited high

99 ee miRNA KO mice produced greater numbers of ducts compared to controls.

100 in cholangiocytes that formed reactive bile ducts compared with control liver tissues.

101 y neoplasms (IOPNs) of the pancreas and bile duct contain epithelial cells with numerous, large mitoc

102 y rates were determined in 423 positive bile duct cultures and 197 corresponding blood cultures obtai

103 s results in proximal tubular and collecting duct cysts, respectively.

104 ces enhance volume removal through lymphatic duct decompression.

105 cts produced exophytic growth, whereas large ducts deformed endophytically.

106 stically, we showed that Yap/Taz mutant bile ducts degenerated, causing cholestasis, which stalled th

107 haracterized by the persistence of Mullerian duct derivatives, uterus and tubes, in otherwise normall

108 ntially distributes to kidney and collecting duct-derived cysts, displaces miR-17 from translationall

109 zes Hippo signaling in the liver during bile duct development by binding to Hippo pathway effector pr

110 hich mutations in ciliary genes lead to bile duct developmental abnormalities is not understood.

111 terval (95% CI) 1.80-3.69], small pancreatic duct diameter (per mm increase, OR: 0.68, 95% CI: 0.61-0

112 nd lumen formation, as well as mammary gland duct diameter and branching.

113 Median pancreatic duct diameter was 3 mm [interquartile range (IQR = 2-4)]

114 Clinical variables including age, sex, main duct diameter, cyst size, mural nodule, and tumour locat

115 into the regulatory network controlling bile duct differentiation and morphogenesis during liver deve

116 in multivariate regression, main pancreatic duct dilation >5 mm (odds ratio, 14.98; 95% confidence i

117 erval, 2.63-108; P < .0012), main pancreatic duct dilation >=1 cm (odds ratio, 47.9; 95% confidence i

118 14.4 vs 5.6%, p = 0.001) and main pancreatic duct dilation (13.4 vs 5.6%, p = 0.004) were associated

119 ars, preoperative size >2 cm, and pancreatic duct dilation were independently associated with aggress

120 mber of patients diagnosed with chronic bile duct disease is increasing and in most cases these disea

121 ghout sperm migration along the spermathecal ducts during ovulation to fertilize the descending egg.

122 egulated in mouse kidney cortical collecting duct epithelial cells.

123 d with cells within glomeruli and collecting duct epithelial cells.

124 enitor cells and are able to respond to bile duct epithelial loss with proliferation, differentiation

125 revealed decreased PKD1L1 expression in bile duct epithelium when compared to normal livers and liver

126 bile duct cancer that originates in the bile duct epithelium.

127 lines of IPMNs still consider it as a branch-duct, even though it is the main drainage system for the

128 Although laparoscopic common bile duct exploration (LCBDE) deals with gallstones and ducta

129 entity, and transitioned toward a collecting duct fate.

130 mechanical drainage of obstructed pancreatic ducts for some patients.

131 transport in the outer medullary collecting duct from the inner stripe (OMCDi) is not known.

132 cro dissect patient-derived human pancreatic ducts from pancreatic remnant cell pellets, followed by

133 -216b KO mice was the presence of pancreatic duct glands (PDGs).

134 sed by a chronic and destructive, small bile duct, granulomatous lymphocytic cholangitis, with typica

135 9 [0.44-0.80]), whereas a dilated pancreatic duct (>3 mm) and pancreatic ductal adenocarcinoma (PDAC)

136 hobe histology, and four (4%) had collecting duct histology.

137 DR is pathologically recognized as bile duct hyperplasia and is commonly observed in biliary dis

138 tes prepared from inner medullary collecting duct (IMCD) suspensions.

139 dic platform that juxtaposes a human mammary duct in proximity to a perfused endothelial vessel.

140 ured essential features of a simplified bile duct in structure and organ-level functions and represen

141 luminal diameter and area of the pancreatic duct in the control group was significantly larger than

142 ot only the tubular architecture of the bile duct in three dimensions, but also its barrier functions

143 expression in cysts derived from collecting ducts in ADPKD.

144 In collecting ducts in CFTR knockout mice, baseline pendrin activity w

145 tructural continuity between hepatocytes and ducts in disorders affecting hepatocytes.

146 n all of the nephron segments and collecting ducts in mice after kidney development.

147 phological changes were observed in the bile duct, including ductal epithelial proliferation, micropa

148 erized by the proliferation of reactive bile ducts induced by liver injuries.

149 CVS contributes to the stable rates of bile duct injuries in LC.

150 bile biochemistry for the assessment of bile duct injury (BDI).

151 ommon associated complications included bile duct injury (n = 397), bowel perforation (n = 96), and h

152 olarity signalling components following bile duct injury and promote the formation of ductular scars

153 he development of cholestatic liver and bile duct injury in mouse models of sclerosing cholangitis, a

154 Bile duct injury was induced by the administration of 3,5-die

155 n biliary stricture occurs secondary to bile duct injury, anastomotic narrowing, or chronic inflammat

156 the portal region, without evidence of bile duct injury.

157 chiophyllum plant shares the presence of gum ducts inside leaves with its presumed extant relative th

158 ole in liver regeneration by preserving bile duct integrity and securing immune cell recruitment and

159 M range and its infusion into the pancreatic duct is commonly used to study pancreatitis.

160 Furthermore, dilated bile duct is the only risk factor for bile duct stone recurre

161 ly viscous secretions that obstruct proximal ducts leading to fibrotic injury and ultimately pancreat

162 Oncogenic transformation of pancreatic ducts led to two types of neoplastic growth: exophytic l

163 their geometrical features (diameter ratio, duct length ratio) as the entire blood flow architecture

164 TSC niche in these patients, the presence of duct lesions at different stages suggests a progressive

165 agonists inhibit biliary hyperplasia in bile-duct ligated (BDL) rats, whereas 5HTR2B receptor antagon

166 damage/senescence and liver fibrosis in bile duct ligated and Mdr2(-/-) (alias Abcb4(-/-)) mice throu

167 In livers of mice subjected to bile duct ligation (BDL) and in cultured activated hepatic st

168 Our results show that the bile duct ligation (BDL) experimental model of cholestasis le

169 the detailed hemodynamics of mice with bile duct ligation (BDL)-induced liver fibrosis, by monitorin

170 estatic liver injury and fibrosis after bile duct ligation (BDL).

171 ts and mice with liver fibrosis (due to bile duct ligation [BDL] or administration of carbon tetrachl

172 e studied 4-weeks after sham surgery or bile duct ligation and were injected with saline or LPS to mi

173 Pancreatic duct ligation in a minipig model leads to exocrine pancr

174 rine pancreatic insufficiency via pancreatic duct ligation in minipigs and the long term follow up of

175 Pancreatic duct ligation in minipigs is an excellent method of indu

176 In beta-Arr2-deficient mice, bile duct ligation injury (BDL) led to significantly reduced

177 A 4-week bile duct ligation model was used to develop cirrhosis with H

178 nd fibrosis or were subjected to either bile duct ligation or CCl(4) injury.

179 Mice underwent bile duct ligation or were fed 3,5-diethoxycarbonyl-1,4-dihyd

180 14 Goettingen minipigs underwent pancreatic duct ligation via midline laparotomy for the induction o

181 induced severe acute pancreatitis by partial duct ligation with caerulein stimulation or intraperiton

182 From approx. 130 weeks post pancreatic duct ligation, all animals were supplemented with pancre

183 through carbon tetrachloride treatment, bile duct ligation, and 0.1% 3,5-diethoxycarbonyl-1,4-dihydro

184 pedes liver fibrosis induced by CCl(4), bile duct ligation, and more importantly NASH.

185 y inhibited the fibrogenic phenotype in bile duct ligation- or thioacetamide-treated mice.

186 -selective knockout of EZH2 exacerbates bile duct ligation-induced fibrosis whereas MDR2(-/-) mice ar

187 20 mM (5%) STC into the pancreatic duct, and duct ligation.

188 pared with control mice after pIVCL and bile-duct ligation; neutrophil recruitment into sinusoidal lu

189 PDAs develop from duct-like cells through a multistep carcinogenesis proce

190 y PDAC, whereas CD9(low) cells produced only duct-like epithelial progeny.

191 of YAP transcriptional activity in the bile duct-lining epithelial cells.

192 cterize tissue-emigrant lineages in thoracic duct lymph (TDL).

193 t (CXCR5BrPD-1Br) Tfh population in thoracic duct lymph (TDL).

194 a ear trumpet), the geometry of the cochlear duct manifests tapering symmetry, a felicitous design pr

195 tors in Mdr2KO mice resulted in reduced bile duct mass and hepatic fibrosis.

196 sence or activation; large intrahepatic bile duct mass, inflammation and senescence; and fibrosis, an

197 blished, localized transport via the mammary ducts may be improved with tailored drug delivery formul

198 Patients were categorized into main-duct (MD-IPMN) versus branch-duct (BD-IPMN).

199 ecifically, recent evidence linking non-bile duct medical conditions, such as nonalcoholic fatty live

200 how that ANKS6 function is required for bile duct morphogenesis and cholangiocyte differentiation.

201 t regulatory mechanisms involved in cochlear duct morphogenesis and establishment of its constituent

202 ll polarity is fundamental for mammary gland duct morphogenesis during mammalian development.

203 impairs pancreatic bud fusion and pancreatic duct morphogenesis.

204 d regulatory sequences that promote cochlear duct morphogenesis.

205 ned as a new IPMN, increased main pancreatic duct (MPD) size, and increased size of an existing lesio

206 nitor-like cells within the major pancreatic ducts (MPDs) of the human pancreas.

207 multiple cell types including the collecting ducts, nephrons, vasculature and interstitium.

208 nastomosis (duct-to-duct, telescopic duct-to-duct), number of graft biliary duct (=1 versus >1), numb

209 andard treatment for congenital nasolacrimal duct obstruction (CNLDO) among children, the optimal tim

210 omy (MMED) for primary acquired nasolacrimal duct obstruction (PANDO).

211 eonatal liver disease with extrahepatic bile duct obstruction and progressive liver fibrosis.

212 focal bile duct stricture formation and bile duct obstruction.

213 ical signs of inflammation/fibrosis and bile duct obstruction.

214 son and APACHE II scores and markers of bile duct obstruction.

215 P obtained with 3T scanners in cases of bile duct obstruction.

216 cision-cut slices of extrahepatic human bile ducts obtained from discarded donor livers, providing an

217 f the jugular lymph sacs/primordial thoracic ducts, oedema and embryonic lethality.

218 +) PMCs were found only surrounding the main duct of a portal tract but not the epithelial cells of t

219 .001), presence of a dilated main pancreatic duct of over 4 mm (P < 0.001), histopathologically detec

220 or Ire1alpha, specifically in the collecting ducts of neonatal mice.

221 number of hyperplastic foci was reduced, the ducts of the VP and MG became atrophic, and, in the VP,

222 This bile duct-on-a-chip captured essential features of a simplifi

223 Here, we report on a bile duct-on-a-chip that phenocopies not only the tubular arc

224 in close proximity to the either the acinar duct or its valve, respectively.

225 oronaviruses through incorporation into HVAC ducts or recirculating air purifiers.

226 genetically labeled adult kidney collecting duct principal cells after Hes1 inactivation or lithium

227 P2-expressing cells and in kidney collecting duct principal cells.

228 ncreasing AQP-2 expression in the collecting duct principal cells.

229 into the plasma membrane of renal collecting duct principal cells.

230 nalyze the clinical efficacy of nasolacrimal duct probing among patients with CNLDO symptoms at vario

231 ents (3009 eyes), who underwent nasolacrimal duct probing conducted under topical anesthesia in the o

232 Although nasolacrimal duct probing is the standard treatment for congenital na

233 ent with theory predictions-small pancreatic ducts produced exophytic growth, whereas large ducts def

234 A significant pathological side effect, bile-duct proliferation, was seen in the liver of AAV2-LDLR r

235 interstitial kidney injury, using collecting duct proteostasis defects as a platform for discovery of

236 ist in patients without cirrhosis with large-duct PSC.

237 d formation in vitro and prostate epithelial duct regeneration in vivo.

238 in the Sox2-positive domain of the cochlear duct, resulting in down-regulation of Tead gene targets.

239 y formation and in the developing collecting ducts results in proximal tubular and collecting duct cy

240 Hepatic duct samples (n = 10) were obtained from patients affect

241 In perfused cortical collecting ducts, secretin stimulated pendrin-dependent Cl(-)/HCO(3

242 ssing cells in distal nephron and collecting duct segments in adult kidneys.

243 to identify and ligate accessory pancreatic ducts since persistence of accessory ducts will lead to

244 ting of body mass index, pancreatic texture, duct size, and male sex, showed good discrimination (AUC

245 Postischemic bile duct slices were incubated in oxygenated culture medium

246 Conversely, female sex, small duct, soft gland, minimally invasive approach, pylorus-p

247 d reporter mouse models to enrich collecting duct specific PC and ICs and reported targeted gene expr

248 AC) ), and Edn1 connecting tubule/collecting duct-specific conditional knockout mice (Edn1(AC) ), und

249 wild-type mice, connecting tubule/collecting duct-specific Dot1l conditional knockout mice (Dot1l(AC)

250 Renal collecting duct-specific gene deletion of CCN2 significantly reduce

251 type mice to those of mice with a collecting duct-specific knockout of the transcription factor grain

252 balloon dilation (EST-EPLBD) for large bile duct stone extraction with an extent of cutting < 1/2 th

253 d bile duct is the only risk factor for bile duct stone recurrence in patients undergoing limited EST

254 bile duct was the only risk factor for bile duct stone recurrence in the limited EST-EPLBD group.

255 expansion balloons according to common bile duct stone size.

256 The removal of large bile duct stones (> 15 mm) by conventional endoscopic sphinct

257 8 years) with native papilla and common bile duct stones (<=1.5 cm in size and <2 cm in diameter) und

258 ventional surgical management of common bile duct stones (CBDS).

259 , 3721 consecutive patients with common bile duct stones were recruited, 1718 of whom were excluded.

260 We enrolled 185 patients with >=15 mm bile duct stones who received EST, EPLBD and limited EST-EPLB

261 dilation time for the removal of common bile duct stones.

262 loon dilation for the removal of common bile duct stones.

263 is the established treatment for common bile duct stones.

264 ary growth of biliary epithelium, focal bile duct stricture formation and bile duct obstruction.

265 valved pump constricted to a narrow salivary duct supplying outgoing enzymes for food fluidization.

266 The persistent Mullerian duct syndrome (PMDS) is a 46,XY disorder of sexual devel

267 ients(2) with case reports of vanishing bile duct syndrome(3), subacute biliary injury and immune cho

268 ly caused by iatrogenic injuries of the bile duct system.

269 eakage, type of biliary anastomosis (duct-to-duct, telescopic duct-to-duct), number of graft biliary

270 FRA1 gene encodes a receptor on the Wolffian duct that regulates ureteric bud outgrowth in the develo

271 tubule and the H+-pump along the collecting duct), the model yields segmental deliveries and urinary

272 y bile salts during passage through the bile ducts to the gut(4).

273 onnects the intrahepatic and intrapancreatic ducts to the intestine and ensures the afferent transpor

274 iliary anastomosis (duct-to-duct, telescopic duct-to-duct), number of graft biliary duct (=1 versus >

275 , bile leakage, type of biliary anastomosis (duct-to-duct, telescopic duct-to-duct), number of graft

276 increased in split-open isolated collecting duct tubules, while ENaC protein levels remained unchang

277 Bile duct tumors are rare and have poor prognoses.

278 Patients with bile duct tumors had multiple alterations at the KIR gene loc

279 orm to study the pathophysiology of the bile duct using cholangiocytes from a variety of sources.

280 cells of the oral mucosa and salivary gland ducts via ACE2 receptors.

281 The thoracic duct was elongated 10% ( P=0.0409) and with an abnormal

282 Furthermore, dilated bile duct was the only risk factor for bile duct stone recurr

283 tudy arm, the efficacy of CPX NS (1, 3, 5 mg/duct) was evaluated.

284 eal lymphatics, cisterna chyli, and thoracic duct were viewed with an accuracy of 23 of 25 (92%), 24

285 e density of lesions along extrahepatic bile ducts were measured and compared with pathology and/or E

286 cholangiocytes, epithelial cells lining bile ducts, were cultured as polarized epithelia in a Transwe

287 In the renal collecting duct, which is a typical absorptive tight epithelium, co

288 The portal tract contains the bile duct, which is surrounded by stromal cells often called

289 cholangitis (PBC) is a disease of small bile ducts, which can lead to morbidity and mortality.

290 dye via both the stratum corneum and mammary ducts, while the 80% and 70% water formulations moderate

291 creatic ducts since persistence of accessory ducts will lead to maintenance of exocrine pancreatic fu

292 Tilt-rotor/duct/wing VTOLs are efficient when cruising but consume

293 The test case used is a standard duct with back facing step where the optimizer aims at m

294 lymph nodes, pancreas and extrahepatic bile duct with potential for recurrence and persistent local

295 Ducts with neoplastic lesions showed higher inflammation

296 rmore, pretreatment of split-open collecting ducts with the synthetic agonist peptide significantly i

297 sections revealed the prevalence of mucilage ducts within stipes and fronds (absent in Lessonia) and

298 ls were dissected after division of the bile duct without a porto-caval shunt.

299 cinar cells and cystically dilated secretory ducts without islets of Langerhans.

300 es the amount of scar formed around the bile duct, without reducing the development of the pro-regene