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1 extracted, and their quality was assessed in duplicate.
2 d data from these articles were extracted in duplicate.
3 , and assessed risk of bias independently in duplicate.
4 utcomes were abstracted independently and in duplicate.
5 tentially eligible articles were screened in duplicate.
6 ment, and quality of evidence assessments in duplicate.
7 ed, and data extracted, independently and in duplicate.
8 ion, and quality appraisal were performed in duplicate.
9 y assessment were performed independently in duplicate.
10 hich 22 codons around the deletion site were duplicated.
11 ts for YES and LYN overexpressing cells were duplicated.
12 synergistic interactions, while MYC is often duplicated.
13 ly continuous process by which the genome is duplicated.
14 (protospacer adjacent motif) combinations in duplicates.
15 ccount for these errors when identifying PCR duplicates.
16 -biased expression, many of which are recent duplicates.
17  21 065 studies remaining after exclusion of duplicates, 1081 full-text articles were assessed for el
18       The Pst-resistant allele YrAS2388R has duplicated 3' untranslated regions and is characterized
19                 DNA replication is needed to duplicate a cell's genome in S phase and segregate it du
20                     The recognition that the duplicated ACCase in Arabidopsis is an impediment to pla
21        We identify and characterize over 50% duplicated accessions both within and across genebank co
22 lication in 96 million years or more, tandem duplicates accumulate relatively more SNPs than paralogo
23  alba) to suppress the expression of its two duplicate AG orthologues.
24  generated by functional specialization of a duplicated ancestral gene.
25                  Reviewers extracted data in duplicate and independently and assessed the certainty o
26                 Trained staff measured RR in duplicate and SpO(2) in triplicate in children who had n
27 ar organisms >600 million years ago and then duplicated and diversified from ancestral genes across t
28 ic and nuclear FGF7 in MDA-MB-231 cells were duplicated and mistaken for total FGF7 in SKBR-3 and MDA
29 ntegrity over generations as chromosomes are duplicated and segregated during each cell cycle, and in
30 omplexes show a higher retention of genes in duplicated and triplicated copies.
31 s, provides strong evidence that this highly duplicated and underexamined protein domain family plays
32                                   We removed duplicates and participants with missing data and used a
33  unique mature miRNAs (excluding mir430 gene duplicates and the vaultRNA-derived mir733), which doesn
34                             After removal of duplicates and title and abstract screening, we screened
35         Data were extracted independently in duplicate, and findings pooled using inverse variance me
36            "Daisy-drive" systems can locally duplicate any effect achievable by using an equivalent s
37 sm susceptibility increases when deleting or duplicating any point of pLI.
38 spliced forms such that the products of each duplicate are localized to only one of the original loca
39  to anthracnose infection, whereas polyploid duplicates are not, supporting the general view that col
40               Finally, reciprocally retained duplicates are often subject to dosage balance constrain
41 ree dimensional space, while coding sequence duplicates are rare, GC-rich, short, and tend not to int
42 hermore, transcriptome data show that tandem duplicates are significantly up- and down-regulated in r
43                                          The duplicate article has therefore been withdrawn.
44                               Of the 521 non-duplicate articles found, 58 articles were included in t
45                              Centrioles must duplicate as cells progress through the cell cycle but i
46                              Also CIN2 genes duplicated before the diversification of Saruma and Asar
47 a strong sweep containing a pair of tandemly duplicated bromelain inhibitors.
48 cts, and full-text articles were screened in duplicate by two investigators.
49              The spectrum of A2-red could be duplicated by combining those from A3-purple and A4-oran
50 response to changes in luminal [Ca(2+)], was duplicated by exposing native RyR2 channels to subphysio
51 patients exposed to the drug of interest and duplicate cases that are difficult to identify.
52 n Eutrema, individual down-regulation of the duplicated CBL10 genes (EsCBL10a and EsCBL10b) decreased
53 ved framework of proteins that segregate the duplicated cellular organelles into two daughter cells d
54 hromosome segregation, when one of the newly duplicated centromeres moves across the cell to the oppo
55  cells with polyploidy, increased numbers of duplicated centrosomes, and vulnerability to anaphase or
56 omosome segregation requires kinetochores on duplicated chromatids to biorient by attaching to dynami
57                       The energetic costs of duplicating chromatin are large and therefore likely dep
58                                 Partitioning duplicated chromosomes equally between daughter cells is
59 lin C, cells enter mitosis with incompletely duplicated chromosomes, and subsequent chromosome segreg
60 cture which accurately aligns and segregates duplicated chromosomes.
61 ed, as random (Co, Cd, 120 degrees C), short duplicates (Co, Cd, 85 degrees C), long duplicates (Co,
62 hort duplicates (Co, Cd, 85 degrees C), long duplicates (Co, Pb, 85 degrees C), and insertions (Co, M
63 s revealed that SM genes tend to be tandemly duplicated, coexpressed with their paralogs, narrowly ex
64 f germplasm often results in unintentionally duplicated collections with poor characterization and ma
65 divergent in expression and have more recent duplicates compared to annotated genes.
66 somes in mitosis requires that the genome be duplicated completely prior to anaphase.
67  the general view that collections of tandem duplicates contribute evolutionarily recent "tuning knob
68                                              Duplicated control regions are found in the Aeolothripid
69 BCGM divergence and expression difference of duplicate copies.
70 ociated with a massive overexpression of the duplicated cytochrome P450 genes CYP6P9a and CYP6P9b, an
71                                 Studies with duplicate datasets, not available in English, and that d
72  and validated the results with the use of a duplicate diet analyses.
73 ry analyses and 935+/-329.9mg estimated by a duplicate diet analyses.
74  comparisons through diet diary analyses and duplicate diet for other elements showed good agreement,
75 that obtain through an elemental analysis of duplicate diets, with a mean+/-sd daily intakes of 956+/
76                                     Inverted duplicate DNA sequences in both yeast and human samples
77 sential process for the equal segregation of duplicated DNA into two daughter cells during mitosis.
78 le is to duplicate the genome and divide the duplicated DNA into two daughter cells.
79                                     Inverted duplicated DNA sequences are a common feature of structu
80         Analysis of CNVs containing inverted duplicated DNA sequences using nanopore sequencing ident
81                  The coincidence of inverted duplicated DNA sequences with dramatically reduced seque
82 genome instability arising from incompletely duplicated DNA via regulatory control of its ATR-stimula
83 e fewer coding sequence mutations outside of duplicated domains than RIP-proficient strains.
84 ranscriptional plasticity of genes that have duplicated during aphid evolution.
85                               After removing duplicates, each of the 158 variants was annotated and i
86                                  A and B had duplicate effects on LR, and both showed dominant epista
87 lective sweeps were enriched among polyploid duplicates encoding key developmental and physiological
88 on factor diversity of avocado, while tandem duplicates enhanced the secondary metabolism of the spec
89 the workings of an evolutionary fail-safe, a duplicate enhancer mechanism that is hard-wired in the m
90  shadow enhancer pair can better buffer than duplicated enhancers.
91 y published, the authors mistakenly included duplicate entries in the flake datasets for the new Pech
92  Washington State University for finding the duplicate entries in the published flake dataset.
93 s tested the 40-isolate (20 unique isolates, duplicated) EQA panel at three time points.
94 , highly expressed transcript encoded by the duplicated exons.
95                Moreover, tandem and proximal duplicates experienced stronger selective pressure than
96 th conserved expression and ancient retained duplicates, features that were not part of the model, ar
97 ical reproducibility was high, with ICCs for duplicate fecal samples between 0.64 and 1.00.
98                    This insertion includes a duplicated follistatin gene, which is a strong candidate
99          Each included study was assessed in duplicate for adherence to the 18-item SQUIRE 2.0 criter
100 pective CrAg-screening cohort were tested in duplicate for CrAg by the CrAgSQ (IMMY) and CryptoPS (Bi
101 in fibroblasts derived from a DS mouse model duplicated for some Hsa21-orthologous genes, indicating
102 using the Dp1Tyb mouse model of DS, which is duplicated for the entire Hsa21-orthologous region of mo
103 ing and linking methods, where the linker is duplicated from a known inhibitor, appears as an interes
104 g representative blots, and were erroneously duplicated from GluA2.
105                                         Gene duplicates from the paleohexaploid event were enriched f
106 ates along this trajectory comprise sequence-duplicated functional proteins built from 10 amino acid
107  to resolve the last gene-rich gaps, improve duplicate gene annotation, and better understand copy-nu
108 n different plants, we constructed the Plant Duplicate Gene Database.
109 red the developmental expression patterns of duplicate gene pairs and the relationship between develo
110                                We found that duplicate gene pairs comprised of two essential genes te
111 different stages of development, compared to duplicate gene pairs with at least one non-essential mem
112  following whole-genome duplication and that duplicate gene retention patterns are shaped by selectio
113 xa, and unravel common principles underlying duplicate gene retention.
114                             We show that the duplicated gene CYP82C2 has been recruited into the WRKY
115                                            A duplicated gene may have a similar function to its ances
116          To provide a platform for accessing duplicated gene pairs in different plants, we constructe
117 al without the presence of a quasi-identical duplicated gene, SMN2, specific to humans.
118 ning expression divergence between copies of duplicates generally holds for duplicates generated by w
119 een copies of duplicates generally holds for duplicates generated by whole genome duplication (WGD) o
120                                              Duplicate genes (i.e., homeologs, in the case of a whole
121                 The functional divergence of duplicate genes (ohnologues) retained from whole genome
122 for the analysis of the expression ratios of duplicate genes across two conditions (e.g., tissues).
123                    The number of WGD-derived duplicate genes decreases exponentially with increasing
124                                              Duplicate genes descending from polyploidy augmented the
125                           A primary way that duplicate genes evolve new functions is by altering thei
126         Comparing the expression patterns of duplicate genes gives clues as to whether any of these e
127 nd phenotypes resulting from the knockout of duplicate genes in the mouse.
128                                        While duplicate genes may retain some functional redundancy, i
129 er investigation of the dynamic evolution of duplicate genes.
130 arking may facilitate long-term retention of duplicate genes.
131 g on methods that allow for the inclusion of duplicated genes (paralogs).
132 with a focus on cis-trans interactions among duplicated genes and alleles in hybrids and allopolyploi
133 ana) plastid preproteins encoded by recently duplicated genes and show that, within a duplicated prep
134 DNA methylation and expression divergence of duplicated genes and suggested a role of epigenetic mech
135 tablish a more complete understanding of how duplicated genes and TEs contribute in concert to chemic
136                                              Duplicated genes are a major contributor to genome evolu
137 ng suggest that evolutionary trajectories of duplicated genes are dictated by combined functional and
138                                         Most duplicated genes are eliminated, and factors that influe
139           Therefore, it may be expected that duplicated genes are less likely to be critical for the
140 xpressed in early spermatocytes, while young duplicated genes are often bimodally expressed.
141              However, it remains unclear how duplicated genes are wired into existing regulatory netw
142                  In multicellular organisms, duplicated genes can diverge through tissue-specific gen
143 synthetic enzymes are present in clusters of duplicated genes in the M. truncatula genome.
144                                        These duplicated genes may have been free to diverge in functi
145 Arabidopsis, CGL20 is encoded by segmentally duplicated genes of high sequence similarity (AtCGL20A a
146                                We found that duplicated genes often accumulate more transcripts.
147                                              Duplicated genes preferentially retained include photosy
148 affect functional features, and overlap more duplicated genes retained from an ancestral salmonid aut
149 usive functional evidence linking new and/or duplicated genes to NCC evolution is lacking.
150                                     Although duplicated genes undoubtedly shape each other's evolutio
151 le of concerted divergence of simultaneously duplicated genes whose products function in the same com
152                  Among the possible fates of duplicated genes, subfunctionalization refers to duplica
153 d pipeline (SBP) is most suited for recently duplicated genes, whereas the protein-family-based metho
154 ivergence is a previously unreported fate of duplicated genes.
155 sure the bulk of the chromatinization of the duplicating genome.
156 ed the basic principles of how the replisome duplicates genomic DNA, but little is known about its dy
157 ntages of agreement and kappa statistics for duplicate gradings of baseline color non- simultaneous s
158 f disagreements of two or more steps between duplicate gradings, led to some improvement in reproduci
159 th millipedes, but unlike in insects, an AGO duplicate has become a pseudogene.
160 man experts from different labs, essentially duplicating human capability.
161                    A factorial design with a duplicate in the central point was used to investigate t
162                                     This was duplicated in a cell line (RBL-MRGPRX2).
163    All class II TCP genes have independently duplicated in Aristolochia subgenus Siphisia.
164 te (AGO) proteins for loading small RNAs are duplicated in both millipedes, but unlike in insects, an
165 strate that the ACE1 cluster is specifically duplicated in Clade 2, a dominant clade in indica rice-g
166 ss amyloid precursor protein (APP), which is duplicated in DS and in Ts65DN mice; however, normalizin
167 in which the same chromosomal region that is duplicated in Dup22q11.2 is deleted.
168                               CBL10 has been duplicated in Eutrema (Eutrema salsugineum), a salt-tole
169 authors noted that images were inadvertently duplicated in Fig.
170 t patients reveals that HYDIN2 is deleted or duplicated in most cases.
171 ltransferase as chromatin patterns are being duplicated in proliferating cells, predisposing them to
172                      However, flanking genes duplicated in some but not all the affected individuals
173 lobine and cow sequences, whereas RNASE1 was duplicated in the common ancestor of A. palliata, A. sen
174 ome is hindered by the large number of genes duplicated in Trisomy 21 and a lack of understanding of
175   Unique molecular identifiers (UMIs) remove duplicates in read counts resulting from polymerase chai
176 le (tandem and transposed) than genome-scale duplicates in sorghum, but the opposite is true in maize
177      Hence, the selective expression of gene duplicates in specialized cell types can synergize with
178 be more frequently tandemly duplicated than "duplicates" in soybean, which may, to some extent, count
179 it-potentially explaining why centrioles can duplicate independently of cell-cycle progression.
180  to avoid inadvertent iatrogenic injury to a duplicated infraorbital nerve.
181                                      The RCT DUPLICATE initiative (Randomized, Controlled Trials Dupl
182 ydrate transport or coenzyme metabolism were duplicated, likely facilitating niche specialisation in
183 ologous crossovers remain unaffected by MSH4 duplicate loss.
184 gories, including a higher proportion of WGD duplicates manifesting expression alteration, and differ
185                        For each participant, duplicate meals (0-96 h), feces (24-120 h), and indoor/o
186                                              Duplicate mean pneumatonometer IOP measurements were col
187 T units should be calculated on the basis of duplicate measurements of at least 10 samples chosen at
188               Methanogenesis was observed in duplicate microcosms that were unamended, amended with s
189 cal samples were collected and analysed with duplicate modified Kato-Katz smears.
190 d from the Asgard archaea-related host being duplicated most.
191 proteomics identified over 6,000 proteins in duplicate multiplexed labelling experiments across two d
192 but a FHR5 mutant has been identified with a duplicated N-terminal SCR-1/2 domain pair that causes CF
193 mes project demonstrated that 70-95% of read duplicates observed in such datasets correspond to natur
194 ith shMSI2 was inadvertently replaced with a duplicate of 7(th) colony image.
195                                 In medaka, a duplicate of dmrt1-acting as master sex-determining gene
196                 1e (imipramine), which was a duplicate of Fig.
197 ary Information, Supplementary Video 2 was a duplicate of Supplementary Video 1.
198                 Our results suggest that the duplicates of alpha-gliadin and GLR genes have likely ta
199 the larger chromosome 1, with growth-neutral duplicates of core genes located primarily on chromosome
200  in panel d were inadvertently replaced with duplicates of those in panel c during final assembly of
201 ed with the cell cycle such that centrosomes duplicate once in S phase.
202                       Centrosomes themselves duplicate once per cell cycle, in a process that is cont
203 The spindle pole body (SPB) of budding yeast duplicates once per cell cycle.
204                                  Images were duplicated: one set was white balanced and color correct
205                                  Centrosomes duplicate only once in coordination with the DNA replica
206 spose to mosaic chromosomal alterations that duplicate or remove the inherited risk alleles, includin
207  all seven examined strains had at least one duplicate pair in which either the genes in the pair wer
208 r known as germ cell-expressed (Gce) and its duplicate paralog, methoprene-tolerant (Met).
209 ltivariate analysis after further removal of duplicate participants and missing data.
210                                 For recently duplicated pathways to acquire different, independent fu
211 hdrew immediately after randomization, and 1 duplicate patient was identified.
212 k height similarity to identify ion adducts, duplicate peak reports, and isotopic features of the mai
213 ative loss-of-function deletions that impair duplicated pheromone receptor genes (srg-36 and srg-37),
214 nvestigate redundant gene function in highly duplicated plant genomes.
215 tly duplicated genes and show that, within a duplicated preprotein pair, the isoform bearing the leuc
216 t damaging SNVs and rare SVs that disrupt or duplicate protein-coding sequence, which suggests that g
217 e new signalling pathways(1,2), but recently duplicated proteins typically must become insulated from
218 strated that a minimal segmental change in a duplicated pseudogene locus is sufficient for immune esc
219                                              Duplicate publication data, studies lacking data on SMR
220  We reveal the key molecular substitution in duplicated pyruvate dehydrogenase genes that underpins o
221  retinoic acid receptors (RARs) to either PD duplicate (RA treatment or RARgamma agonist) or truncate
222 ts because of missing consent or mistaken or duplicate randomisation, 2196 alteplase-eligible patient
223 ts with minimal change disease or FSGS, with duplicate readings to evaluate reproducibility.
224                                        Thus, duplicate reads can be efficiently removed by using a co
225 iplexing, 5' and 3' PCR primer matching, and duplicate reads collapsing.
226 panning an imprinted gene cluster within the duplicated region.
227 they either focus only on removing contained duplicate regions, also known as haplotigs, or fail to u
228 , quality and sensitivity of WES in the PKD1 duplicated regions (exons 1-32) is crucial for its poten
229 nd hypervariable region were observed in the duplicated regions for RSV A and B, and at the G stop co
230 depth and sequencing quality were low in the duplicated regions of PKD1 (exons 1-32) compared with th
231 ng methods, and enables variant detection in duplicated regions of the genome that cannot be mapped u
232 luding heterozygous sites in haploid nuclei, duplicated regions of the genome, and low-coverage depth
233                        We extracted data, in duplicate, related to items of selection bias (sequence
234 s that influence the retention of persisting duplicates remain poorly understood.
235              Following a stepwise process of duplicate removal, title and abstract review, full text
236                                    Following duplicate removal, titles and abstracts were screened fo
237                A total of 955 studies, after duplicates removed, were found by the database search.
238 with those from our 2016 risk assessment and duplicate reports were excluded.
239                        By contrast, only the duplicated response regulator gene is present in the sex
240 norhabditis nematodes, the shared exons have duplicated, resulting in the split of the Yin and Yang i
241 sults support a model in which a locus first duplicates, resulting in a second identical copy, and th
242  in homologous recombination, exemplifying a duplicate retention model in which one copy tends to hav
243 al diversification of paralogues, we tracked duplicate retention patterns, expression-level divergenc
244  suggested a role of epigenetic mechanism in duplicate retention.
245                                          The duplicated RNase in Alouatta has biochemical changes sim
246 erved in such datasets correspond to natural duplicates sampled from genes with high expression and i
247                                              Duplicate samples as well as two individual NGS runs pro
248 od to RNA-Seq, which allows the detection of duplicated samples without relying on identifying incons
249             Two authors independently and in duplicate screened citations and reviewed text of studie
250 he direct product of RIP being mostly in non-duplicate sequence and predominantly not C->T mutations.
251  containing approximately 200 amino acids of duplicated sequence that has undergone accelerated prote
252 seline rate, we show that NAGC slows down as duplicate sequences diverge-until an eventual "escape" o
253  leverages substantially more information in duplicate sequences than used by previous methods and us
254 ing with overall lower mitochondrial DNA and duplicated sequences interference relative to ATAC-see.
255                           This suggests that duplicated sequences likely played a fundamental role in
256  genomes, and struggles in regions of highly duplicated sequences.
257 m-dedup, a fast and RAM-efficient tool to de-duplicate sequencing reads without reference genome.
258 eine concentrations in the generated DPS (12 duplicates) showed a strong correlation ( R(2) = 0.99) t
259 has a relatively larger supply of paralogous duplicates, shows SNP enrichment in paralogous genes.
260  and gene activation occur via this upstream duplicated site, thus explaining the species difference.
261      Patient record numbers were found to be duplicated, so that the number of endophthalmitis cases
262 t a nuclear pore complex associates with the duplicating SPB and helps to insert the SPB into the NE.
263                              We sequenced 12 duplicate sRNA libraries of in-vitro-grown peanut plants
264                                              Duplicate studies and abstracts from scientific meetings
265 f long-range haplotyping through segmentally duplicated subtelomere regions.
266 icated genes, subfunctionalization refers to duplicates taking on different parts of the function or
267      These findings unveil distinct roles of duplicated tandem exon-derived U2AF1 isoforms in the reg
268                         Alternative usage of duplicated tandem exons in U2AF1 produces two isoforms,
269 s" were found to be more frequently tandemly duplicated than "duplicates" in soybean, which may, to s
270 ause RIP preferentially attacks GC-poor long duplicates that interact in three dimensional space, whi
271 blish Nup188 as a component of PCM needed to duplicate the centriole with implications for congenital
272 ation rate, controlling the time it takes to duplicate the genome and complete S-phase.
273    The core function of the cell cycle is to duplicate the genome and divide the duplicated DNA into
274 A replication is elaborately orchestrated to duplicate the genome timely and faithfully.
275 nd CO2 from coal use, China is attempting to duplicate the rapid development of shale gas that has ta
276 ell time solution should be non-negative and duplicate the shape of the desired removal map.
277 teractions, but most in vitro studies cannot duplicate the unique spatial arrangement of cMyBP-C with
278 for the maximized log likelihood incorrectly duplicated the equation for entropy; the equation read b
279 single pair of replisomes is responsible for duplicating the entire 4.6 Mbp circular chromosome.
280 hologram with multiple off-axis plane waves, duplicating the pupils into an array.
281 processing is maintained despite swapping or duplicating the two tRNAs consistent with inhibition of
282 g a loop adjacent to the recognition site by duplicating the volume of the preQ(1)-recognition pocket
283 laced the inherited risk alleles (at MPL) or duplicated them to the homologous chromosome (at FH, NBN
284                Kinases have been extensively duplicated throughout evolution, but little is known abo
285                                              Duplicate TIMFIE sampling showed Pearson's correlation c
286 typal cerebellar nucleus that was repeatedly duplicated to form new regions.
287 utionarily novel folds, after which a subset duplicated to give rise to the complex kinetochore of LE
288         A total of 120 chickens were used in duplicate trials to investigate the effectiveness of LC(
289 rt the presence and functional divergence of duplicated TSH beta-subunit paralogs (tshbetaa and tshbe
290 ost, and the closely related Ifit1b has been duplicated twice, yielding three paralogues: Ifit1, Ifit
291  completed by two reviewers independently in duplicate using standardized algorithms and checklists.
292  internal validity of trials was assessed in duplicate using the Cochrane Collaboration's Risk of Bia
293 TE initiative (Randomized, Controlled Trials Duplicated Using Prospective Longitudinal Insurance Clai
294                    When analyzed on-site, in duplicate, using hand-portable instrumentation, reasonab
295                    After excluding potential duplicates, we identified 614 unique cases of DOAC expos
296 r transcriptional regulation, whereas tandem duplicates were overrepresented by environmental respons
297  One hundred eighteen records remained after duplicates were removed, and 104 records were excluded,
298    Paralogs (tandem duplication and disperse duplicated) were also identified and characterized.
299 n this region, where the CAA-CAG sequence is duplicated, which was associated with later AOO.
300  suffered from the highest proportion of PCR duplicates, while QIAseq failed to deliver across all qu

 
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