ライフサイエンスコーパス: ear

1 dle ear disease as the patient group and 100 ears without a middle ear disease as the control group.

2 cess neurosurgery (12%); solid cancer (11%); ear, nose, and throat infections (7%); and immunomodulat

3 adin-specific IgG/IgG2c (in models 1 and 2), ear swelling (in model 1), gluten-dependent enteropathy

4 The study included 56 ears with a middle ear disease as the patient group and

5 uding microcephaly, palate defects, abnormal ear development, and cardiac defects.

6 sually develop normally, results in abnormal ear and lateral line phenotypes.

7 Here we use the accessible ear of an invertebrate to, for the first time in any ani

8 ) and its phosphorylation by KNR6 may affect ear length and kernel number.

9 h presynaptic and postsynaptic changes after ear occlusion and was only affected by presynaptic chang

10 s functional resemblance to an ear horn (aka ear trumpet), the geometry of the cochlear duct manifest

11 yer in GoogLeNet, a deep CNN, to generate an ear deformity detection model in Matlab.

12 hat through its functional resemblance to an ear horn (aka ear trumpet), the geometry of the cochlear

13 We found an optimal configuration using an ear canal electrode and low-frequency (<300 Hz) sinusoid

14 uitment of neutrophils to the ear dermis and ear draining lymph nodes (dLN) as early as 6-18 h after

15 T is determined by (1) measuring (a) ECG and ear, finger, or toe PPG waveforms or (b) two of these PP

16 ated diseases that affect the brain, eye and ear.

17 he changing relationship between the jaw and ear.

18 -IF and is found primarily in the kidney and ear (outside of the ileum of the GI) offering significan

19 NR6) determines pistillate floret number and ear length.

20 s the time delays between the ECG R-wave and ear PPG foot, R-wave and finger PPG foot [finger pulse a

21 Here, a mosquito's antennal ear is shown to be sensitive to sound levels down to 31

22 is of homeostasis and ageing in the antennal ears of the fruit fly Drosophila melanogaster.

23 nt in Medicaid prior to the first antibiotic ear drop dispensing (index date), and they had to mainta

24 notypes in different tissue regions, such as ear skin and the trachea, tongue, peritoneum, lungs, and

25 zation through the acoustic coupling between ears is influenced by the active processes of both ears.

26 of the massive population of migratory Black-eared kites wintering around the megacity of Delhi-India

27 , the software also allows tracking of body, ears, nose, and forehands for estimation of kinematic pa

28 s influenced by the active processes of both ears.

29 pairs were presented simultaneously to both ears.

30 Both mammalian and bushcricket ears possess a narrow strip of sensory tissue that exhib

31 Triticum aestivum L.) is also contributed by ear photosynthesis beside the other organs like leaves o

32 risk factors included neurosurgery; cancer; ear, nose, and throat infections; and immunomodulating t

33 t with suppression between the two channels (ears) being much weaker than in binocular vision.

34 s from the ipsilateral and the contralateral ear, respectively.

35 ood flow did not change in the contralateral ear.

36 hysical features, such as internally coupled ears, head size, or shape, and audible frequency range,

37 on of post-dentary jaw elements into cranial ear bones occurred several times in mammals(1,2).

38 acteristic low-set, prominent, and/or cupped ears.

39 auditory synapse, more so in already damaged ears, and severely impact auditory sensitivity in cancer

40 to produce sound sensation even in deafened ears.

41 f differentially expressed genes determining ear and tassel architecture within the 3D genome context

42 A backwards-directed ear position, measured at the base of the ear, was most

43 Pistillate florets of drl1 ears are sterile with unfused carpels that fail to enclo

44 In exposed ears, NT3 overexpression increased permanent threshold s

45 middle ear effusion (MEE) samples, external ear canal (EEC) lavages, and nasopharynx (NPH) samples f

46 iphery in sensory tissues of the head (eyes, ears, various oronasal regions), bone, spinal cord, adre

47 PPG foot (toe PAT), ear and finger PPG feet, ear and toe PPG feet, and finger and toe PPG feet.

48 dental surgery; 3.81 (95% CI 3.11-4.67) for ear, nose, and throat infection; 2.85 (95% CI 2.21-3.70)

49 hroat infection; 2.85 (95% CI 2.21-3.70) for ear, nose, and throat surgery; 15.6 (95% CI 9.57-25.4) f

50 and trans-regulatory modules responsible for ear- and tassel-specific gene expression.

51 Neutrophils from ear dLN of LdCen(-/-) -immunized mice exhibited heighten

52 than expected functional transformation from ear to cortex.

53 Transdermal delivery of LNG from earring patches across porcine skin ex vivo achieved a s

54 ers that recruit GGA (Golgi-localized, gamma-ear-containing, ARF-binding protein), clathrin adaptors,

55 d: negative malaria testing, reporting head, ears, eyes, nose and throat (HEENT) symptoms (i.e., coug

56 MRI) and compare the results between healthy ears and those with a middle ear disease.

57 ST)) at the basal cochlea in cadaveric human ears, and estimated hearing by the cochlear input drive

58 d contralateral to the most hearing-impaired ear compared with the ipsilateral side.

59 Defects in ear canal development can cause severe hearing loss as s

60 ulation of differentially expressed genes in ear and tassel controlling inflorescence architecture.

61 as early as 2 days after tumor initiation in ear TME.

62 addition to its previously reported role in ear development, hmx3a is required for correct specifica

63 Included ear drops were ofloxacin, ciprofloxacin plus hydrocortis

64 n inflammation, as demonstrated by increased ear thickness and increased mRNA levels of key proinflam

65 y (CHS) response to oxazolone with increased ear swelling, T-cell infiltration, and expression of Ifn

66 ated the clinical severity of Aldara-induced ear thickening in icIL-1Ra1(-/-) mice.

67 lycolate-induced peritonitis or MIP2-induced ear pouch inflammation.

68 een isolated several times from the inflamed ears of Zebu cattle in Eastern Africa, where it is assoc

69 Inner ear MRI without contrast gives relevant information to a

70 Inner ear sensory afferent connections establish sensory maps

71 roinjected ASO directly into the E12.5 inner ear.

72 ach to diagnosing patients with active inner ear disease.

73 ve study including patients who had an inner ear MRI for two months.

74 different structures of the middle and inner ear (0 = not visualized, 3 = perfectly identified and de

75 trategies for genetic hearing loss and inner ear development.

76 ion of let-7 in HC differentiation and inner ear morphogenesis.

77 vation of cell cycle activator Myc and inner ear progenitor gene Notch1 induces robust proliferation

78 morphotype, including its endocast and inner ear, to reveal its morphology for the first time.

79 ormities of the limbs, neural tube and inner ear.

80 h are expressed in both the kidney and inner ear.

81 al malformations of the middle ear and inner ear.

82 riving force for sound transduction by inner ear hair cells.

83 mits CHD7 expression in the developing inner ear, retina and brain.

84 play multiple roles in the developing inner ear.

85 t of reliable biomarkers for different inner ear diseases.

86 During inner ear development, primary auditory neurons named spiral g

87 ng the way for treatment with emerging inner ear gene therapy.

88 ws of external and internal (endocast, inner ear) cranial structures.

89 correction of a mutation in the fetal inner ear prior to maturation of the sensory epithelium will o

90 in developing miRNAs as biomarkers for inner ear disease is linking patterns of miRNA expression in p

91 2.7m8 is an excellent viral vector for inner ear gene therapy targeting cochlear hair cells and suppo

92 expand the potential applications for inner ear gene therapy.

93 To develop treatments for genetic inner ear disorders, we designed gene replacement therapies us

94 FGF8 signaling plays diverse roles in inner ear development, acting at multiple stages from otic pla

95 hat noise exposure leads to changes in inner ear metabolism, the specific effects of noise exposure o

96 cription factor complex in maintaining inner ear progenitors during development, and suggest new stra

97 ing postnatal development in the mouse inner ear gata3 is required for the biophysical maturation, gr

98 Vs (AAV2.7m8 and AAV8BP2) in the mouse inner ear.

99 tivity in the tmc1/2a/2b triple mutant inner ear.

100 tes of damage through the detection of inner ear blood-circulating biomarkers.

101 Fifty percent of inner ear disorders are caused by genetic mutations.

102 A key to improving the diagnosis of inner ear disorders is the development of reliable biomarkers

103 of ALD for the prevention/treatment of inner ear disorders such as age-related hearing loss.

104 important for long-term maintenance of inner ear function.

105 l approach for the characterization of inner ear metabolites affected by auditory trauma.

106 The bundle of stereocilia on inner ear hair cells responds to subnanometer deflections prod

107 ch as the cochlear part of the osseous inner ear, that provides optimal contexts for DNA preservation

108 ne delivery of Yap5SA in the postnatal inner ear sensory epithelia in vivo drives cell cycle reentry

109 activities, nervous system processes, inner ear morphology, and cognition, while genetic correlation

110 Since inner ear outer hair cell (OHC) degeneration is a common trait

111 In response to heat stress, inner ear tissue releases exosomes that carry HSP70 in additio

112 e JCI, Breglio et al. demonstrate that inner ear tissue released exosomes carrying heat shock protein

113 within the semicircular canals of the inner ear [4].

114 hair cells and supporting cells in the inner ear and is a widely used sensory marker.

115 anoreceptive sensory hair cells in the inner ear are selectively vulnerable to numerous genetic and e

116 Structures in the inner ear can help determine the evolutionary relationship bet

117 Mechano-sensory hair cells within the inner ear cochlea are essential for the detection of sound.

118 e otic placode lineage, comprising the inner ear epithelium and neurons.

119 ons establish sensory maps between the inner ear hair cells and the vestibular and auditory nuclei to

120 the death of sensory hair cells of the inner ear is an unfortunate side effect for many patients trea

121 h vestibular sensory epithelium in the inner ear is divided morphologically and physiologically into

122 the lateral semicircular canal of the inner ear lies parallel to the horizon when the head is at res

123 powder, and confines the damage to the inner ear region and surface of the petrous portion of fragmen

124 stream transcriptional cascades in the inner ear remain largely unknown.

125 onditional loss of the Yap gene in the inner ear results in the formation of significantly smaller au

126 e the peripheral otolith organs in the inner ear sense both head tilts and translations.

127 of intercellular communication in the inner ear that can mediate nonautonomous hair cell survival.

128 l of molecular agents delivered to the inner ear to ameliorate different types of SNHL.

129 generated by the sensory cells of the inner ear to serve as a sound source microphone for fully impl

130 e located in the ventral region of the inner ear, acts as the primary structure for the perception of

131 s, the mechanosensory receptors of the inner ear, are responsible for hearing and balance.

132 processing of auditory signals in the inner ear, as BACE1-deficient mice exhibit significant hearing

133 In the inner ear, levels of HGF must be fine-tuned for normal hearing

134 The otocyst, an anlage of the inner ear, presents an attractive target to study treatment st

135 ir cells, the sensory receptors of the inner ear, respond to mechanical forces originating from sound

136 formed by specialized receptors of the inner ear, the hair cells.

137 We conclude that, in the inner ear, the noncoding del10 mutation in Hgf leads to develo

138 In the inner ear, these acoustic receptors are primarily attached to

139 rs in the hair-cell stereocilia of the inner ear, which experience continuous oscillations driven by

140 ibe resulting phenotypes solely to the inner ear.

141 n highly specialized hair cells of the inner ear.

142 sory formation of the vestibule of the inner ear.

143 location of cellular damage inside the inner ear.

144 autonomous protective signaling in the inner ear.

145 cted and temporally dynamic throughout inner ear development.

146 ry subunit, which can be transmembrane inner ear (TMIE) or TMEM132e.

147 ner-like 5 (Lhfpl5), and Transmembrane inner ear protein (Tmie).

148 C fusion partner-like 5, transmembrane inner ear, calcium and integrin-binding family member 2, and a

149 The vertebrate inner ear, responsible for hearing and balance, is able to sen

150 llowing blast, and are associated with inner ear mechanotransduction, cytoskeletal reorganization, my

151 of this Tmc subfamily in the zebrafish inner ear, we tested the effects of truncating mutations in tm

152 Inner ears were harvested immediately after exposure and analy

153 al and molecular changes in the middle/inner ears utilizing otoscopy, RNA sequencing (RNA-seq), and h

154 moving 4-hydroxynonenal (4-HNE) in the inner ears of female mice.

155 The middle and the inner ears of WT and Nhe6 KO mice were not different morpholog

156 and the levels of GSTA4 protein in the inner ears.

157 ental-modeling study suggests that (1) inner-ear fluid inertia is an important mechanism for BC heari

158 ate, as they have outer-, middle-, and inner-ear components.

159 echanosensory transduction channels in inner-ear hair cells(6).

160 ural determinants of tip-link-mediated inner-ear sensory perception and elucidate protocadherin-15's

161 new findings are inconsistent with the inner-ear compression mechanism that some have used to explain

162 a computational BC model based on the inner-ear fluid-inertia mechanism, and the simulated effects o

163 noelectrical transduction (MET) in the inner-ear hair cells of larval zebrafish.

164 mplex, which conveys force to open the inner-ear transduction channels that mediate sensory perceptio

165 ing that we show rings true for invertebrate ears too.

166 n inhibit inflammation in a contact irritant ear edema mouse model.

167 amiding desirable characteristics for larger ears.

168 aptured a specimen of the yellow-rumped leaf-eared mouse (Phyllotis xanthopygus rupestris) on the ver

169 word "left" or "right" in the right or left ear, eliciting slower responses when the word and the si

170 validated the results in a murine Leishmania ear infection model.

171 we used the experimentally-accessible locust ear (male, Schistocerca gregaria) to characterize a decr

172 and morphological diversities between maize ear and tassel.

173 chromatin regions (OCRs) in developing maize ear and tassel primordia using ATAC-seq and characterize

174 ungal pathogen that is responsible for maize ear rot and stalk rot diseases worldwide.

175 e husk-the leaf-like outer covering of maize ear-has multiple functions, including protecting the ear

176 Maize ears and tassels are two separate types of inflorescence

177 Outer hair cells (OHCs) in the mammalian ear exhibit electromotility, electrically driven somatic

178 s, are responsible in part for the mammalian ear's vulnerability to permanent balance and hearing def

179 This is in contrast to the mammalian ear, in which stiffness is independent of frequency and

180 Such shape changes are limited in mammalian ears, where supporting cells develop E-cadherin-rich api

181 scence that limits regeneration in mammalian ears.

182 patient group and 100 ears without a middle ear disease as the control group.

183 The study included 56 ears with a middle ear disease as the patient group and 100 ears without a

184 between healthy ears and those with a middle ear disease.

185 Perforation of tympanic membranes and middle ear hemorrhage were observed at 1 and 7 days, and were r

186 uencing, RNA-sequencing of saliva and middle ear samples, 16S rRNA sequencing, molecular modeling, an

187 10) were measured in nasal washes and middle ear tissue homogenate.

188 us) is a principal cause of bacterial middle ear infections, pneumonia, and meningitis.

189 y low or absent in normal or diseased middle ear in mouse and human, and salivary expression and micr

190 atments, such as balloon dilation for middle ear diseases.

191 quisition of the definitive mammalian middle ear in allotherians such as this specimen was independen

192 Here we report a definitive mammalian middle ear preserved in an eobaatarid multituberculate mammal,

193 cal stage of the definitive mammalian middle ear.

194 ition (microbiota) present in matched middle ear effusion (MEE) samples, external ear canal (EEC) lav

195 to NTHi infection in the Junbo mouse middle ear fluid (MEF).

196 chronic low-grade inflammation of the middle ear (ME), without any signs of infection and with effusi

197 atory and reproductive tracts and the middle ear and generate fluid flow in these organs via synchron

198 de developmental malformations of the middle ear and inner ear.

199 ost common infectious diseases of the middle ear especially affecting children, leading to delay in l

200 orms, before the disconnection of the middle ear from the mandible in crown mammals.

201 n to the round window membrane in the middle ear may be able to reverse sensorineural hearing loss.

202 in the biofilms formed by NTHI in the middle ear of the chinchilla in an experimental otitis media mo

203 eveloping, cartilaginous incus of the middle ear, abutting the cranial base to form a cranio-mandibul

204 ement into part of the malleus of the middle ear, and the presence of a restricted contact between th

205 ed development of the ossicles in the middle ear.

206 loss as sound waves fail to reach the middle ear.

207 i strains isolated from children with middle ear infections.

208 But questions remain concerning middle-ear evolution, such as how and why the post-dentary unit

209 layers and structures of ex vivo nude mouse ear skin and extracted pharmacokinetic parameters throug

210 6/Adgrg6 regulates Schwann cell myelination, ear canal formation, and heart development; and GPR126 m

211 and 214 photographs of patients with normal ears.

212 atients (74%) and most commonly consisted of ear or sinus infections (43 of 120, 36%) and cerebrospin

213 odes (75%), which most commonly consisted of ear-nose-throat surgery (19 of 49 episodes [29%]) and re

214 on genes expressed during the development of ear and tassel inflorescences.

215 mographics, calendar year, and the number of ear drop prescriptions was used to compare TMP risk betw

216 Percentage of pruritus of ear and throat was significantly low in pediatric group.

217 hotosynthesis also displayed higher rates of ear assimilation, which translated to increased grain yi

218 trials for the traits grain yield, number of ears, and grain moisture.

219 Suppression of the emissions in one ear often changed the amplitude or shifted the frequency

220 structing subjects to attend to tones in one ear only, while keeping the rhythmic structure of tones

221 ones, and when a masker was presented to one ear, it produced only weak suppression of the response t

222 nger affected localization accuracy when one ear was occluded.

223 response to a signal presented to the other ear.

224 nological reconstructions of annual otolith (ear stone) growth from two ocean basins, we tested wheth

225 seven cohorts into adulthood using otolith (ear stone) chemical archives to identify patterns in tim

226 rms from nearby speakers mix together in our ear canals.

227 amplitude of Period mRNA expression in outer ear skin is dependent on both the light-dark cycle and O

228 Organotypic cultures of murine outer ear and vibrissal skin entrain to a light-dark cycle ex

229 n system involvement including ocular, outer ear, hearing, cardiac, and kidney tissues.

230 The outer ear comprises an air-filled tube derived from the respir

231 ization) or of soluble gliadin or ovalbumin (ear challenge).

232 e (PAT)], R-wave and toe PPG foot (toe PAT), ear and finger PPG feet, ear and toe PPG feet, and finge

233 Quantifying ear deformity using linear measurements and mathematical

234 study examined whether the use of quinolone ear drops increased the risk of perforation with intact

235 Use of quinolone ear drops to treat AOE is associated with a previously u

236 Use of quinolone ear drops was associated with increased risk for TMP com

237 in the ventral skin of New Zealand rabbits' ears.

238 In many reptiles, including the red-eared slider turtle Trachemys scripta elegans (T. script

239 Overall, we found a right ear advantage indicating typical left-hemispheric langua

240 direct attention to either the left or right ear while highly similar syllable pairs were presented s

241 sound streams arriving at the left and right ears, evaluating the perceptual effects it provokes and

242 citation at the entrance of the guinea pig's ear canal.

243 ibited by sound stimuli received at the same ear.

244 nes of the rhythm were presented to separate ears.

245 afish study identifies compounds that shield ears and kidneys against an anticancer drug.

246 lage does not have blood vessels, we studied ear AVMs to determine if overgrown cartilage contained A

247 with progressive hearing loss in the target ear (median baseline WRS, 53%) were enrolled.

248 f sensory structures such as the eye and the ear.

249 EMG recordings showed larger activity at the ear on the side of the attended stimulus, but with sligh

250 Sounds are processed by the ear and central auditory pathway.

251 How does the ear of cold-blooded vertebrates maintain its performance

252 lade II appears to have a propensity for the ear that is uncharacteristic of the other clades, which

253 we successfully reisolated C. bovis from the ear of adult female Zebu.

254 containing Nalpha and Nbeta subtypes in the ear dLN.

255 in Mo17 conferred less N accumulation in the ear leaves and seed kernels resembling that of the zmnlp

256 ated less nitrogen than the WT plants in the ear leaves and seed kernels.

257 hils, we immunized mice intradermally in the ear pinna with LdCen(-/-) Compared with LdWT infection,

258 ns, and aging kill sensory hair cells in the ear, causing irreversible hearing loss and balance defic

259 ious human tissues and organs, including the ear, the brain, the blood, and the lung, and thus in hig

260 ficantly, by performing transplants into the ear pinna, this system enabled intravital observation of

261 e exposure, and increased after ligating the ear canal.

262 coustic spiracle to the internal side of the ear drums in the legs.

263 +)/interferon-gamma(-/-) malignancies of the ear, tail, and foot comprised poorly differentiated, rou

264 ed ear position, measured at the base of the ear, was most strongly associated with the fireworks con

265 the vagus nerve at the cymba conchae of the ear.

266 s that maintain the ionic composition of the ear.

267 ought to reflect distinct pathologies of the ear.

268 were applied in the triangular fossa of the ear.

269 multiple functions, including protecting the ear from diseases infection and dehydration.

270 gain and frequency tuning, and protects the ear from acoustic trauma.

271 Photographs were cropped to the ear boundary and randomly divided into training (60%), v

272 ced higher recruitment of neutrophils to the ear dermis and ear draining lymph nodes (dLN) as early a

273 athematical modeling is difficult due to the ear's complex shape.

274 acoustic driving forces of the tympanum (the ear drum), producing differences in sound pressure and t

275 prevalent sensory disorder begin within the ear at synapses of the primary auditory receptors, their

276 The earring-shaped NLRP3 consists of curved leucine-rich-rep

277 In comparison to the eyes and the ears, the skin is a relatively underexplored sensory int

278 mplex mixtures of sounds often arrive at the ears simultaneously or in close succession, yet they are

279 SOAEs) are weak sounds that emanate from the ears of tetrapods in the absence of acoustic stimulation

280 ethods: Acute or chronic inflammation in the ears of BALB/c mice was induced by 12-o-tetradecanoylpho

281 for request the MRI and the findings in the ears, both in protocols without IVC (p = 0.004) and in p

282 ICANCE STATEMENT Tinnitus, or ringing in the ears, is a neurologic disorder that affects 15% of the g

283 Diverticula that terminate close to the ears improve hearing.

284 proved when the audio received by behind-the-ear devices was converted to haptic stimulation on each

285 Their ears are elaborate, as they have outer-, middle-, and in

286 ions because supporting cells (SCs) in their ears retain lifelong regenerative capacities that depend

287 ike dogs and cats, people do not point their ears as they focus attention on novel, salient, or task-

288 The brain combines sounds from the two ears, but what is the algorithm used to achieve this sum

289 s in the arrival times of a sound at the two ears.

290 n the suborder Caelifera, abdominal tympanal ears first evolved in a non-sexual context, and later co

291 Bush crickets have tympanal ears located in the forelegs.

292 ewing-based stridulation and tibial tympanal ears co-evolved, but in the suborder Caelifera, abdomina

293 In unexposed ears, NT3 overexpression did not affect thresholds, howe

294 Most SCs in vertebrate ears stop dividing during embryogenesis; and soon after

295 deficient DeltadblGATA mice showed only weak ear swelling response, which could be enhanced by eosino

296 This approach enables wheat ears to be detected in the field without the need for ca

297 frequency modulation (FM) cues measured with ear canal EEG recordings.

298 including: 457 photographs of patients with ear deformity and 214 photographs of patients with norma

299 nt meningitis occurs mainly in patients with ear or sinus infections and cerebrospinal fluid leakage.

300 In younger ears, the MOC density peaks in mid-cochlear regions and