ライフサイエンスコーパス: ectopic expression

1 achieved through rescue of MRP RNA levels by ectopic expression.

2 Ectopic expression and CRISPR knockout of USP13 showed t

3 Here we show that ectopic expression and therapeutic delivery of the secre

4 SlDLK2 ectopic expression arrests arbuscule branching and downr

5 upstream of the Ptf1a gene resulting in its ectopic expression at E9.5.

6 Emerging ectopic expression at high copy numbers can be further e

7 growth of primary melanomas in vivo, whereas ectopic expression enhanced proliferation and growth at

8 While NsWOX9 ectopic expression enhances the lam1 mutant phenotype, a

9 y mechanisms to coordinate and prevent their ectopic expression exist.

10 Although ectopic expression experiments have suggested an inhibit

11 ion studies using recombinant viruses and in ectopic expression experiments, assaying for effects on

12 We find that upon ectopic expression in distal limb buds, HOXA11 binds sit

13 n GSDME-expressing tumours enhances, whereas ectopic expression in Gsdme-repressed tumours inhibits,

14 inhibiting TNF-alpha-induced apoptosis upon ectopic expression in HeLa cells, the percentage of infe

15 Ectopic expression in mouse cells and CRISPR/Cas9 base e

16 Upon ectopic expression in primary human articular chondrocyt

17 ONECUT2 ectopic expression in prostate adenocarcinoma synergizes

18 Ectopic expression in the AWA neuron, which is generally

19 n and release of elicitors are the result of ectopic expression in xylem of the gene ARABIDOPSIS DEHI

20 ion in multiple Vibrio species; furthermore, ectopic expression increased the transcription of a Fur-

21 In the cells negative for active p53, NPRL2 ectopic expression leads to activation of CHK1 or CHK2 k

22 Finally, ectopic expression of a chimeric HIPR-1 harboring the hu

23 Ectopic expression of a Lin28b transgene in murine B cel

24 The stable ectopic expression of a mitochondrial outer membrane pro

25 d PTEN expression, which could be rescued by ectopic expression of a PKCalpha expression vector or an

26 Heterologous, ectopic expression of a plant bipartite signaling module

27 factor tetracycline transactivator (tTA) or ectopic expression of a proapoptotic gene, such as head

28 formation of super-enhancers that drive the ectopic expression of a subset of proneural transcriptio

29 Here, we show that the ectopic expression of a truncated RocA derivative, harbo

30 Here we show that, ectopic expression of active nuclear YAP1 (nlsYAP5SA) in

31 Ectopic expression of AFL1 reversed the decrease in FM4-

32 Ectopic expression of AfrLEA6 (AWM11684) in insect cells

33 Conversely, ectopic expression of AGTR1 in cell lines lacking endoge

34 Ectopic expression of Akap12 in renal epithelia results

35 xplains how both loss of Notch signaling and ectopic expression of Akap12 result in similar renal epi

36 Moreover, ectopic expression of AKAP6 in epithelial cells is suffi

37 Additional ectopic expression of an engineered glycosyltransferase,

38 liferation is reversed by COP1 knockdown and ectopic expression of an LT-resistant MKK7-4 fusion prot

39 Ectopic expression of AnxA8 in AnxA8-depleted cells led

40 Ectopic expression of APC, but not its familial adenomat

41 Ectopic expression of ARSA reversed the alpha-synuclein

42 Ectopic expression of BBM1 in the egg cell is sufficient

43 strong prosurvival signals delivered through ectopic expression of BCL2 in B cells could largely resc

44 Ectopic expression of BCL2L14-ETV6 fusions induce distin

45 Conversely, ectopic expression of beta1 integrin was sufficient to i

46 ther regulatory cell types simply by loss or ectopic expression of bHLH genes, and male-to-female and

47 e E10.5 Six1 (-/-) Six2 (+/-) embryos showed ectopic expression of Bmp4, Msx1, and Msx2 messenger RNA

48 reduced vascular cell file numbers, whereas ectopic expression of both TMO5 and LHW can ubiquitously

49 Ectopic expression of BRD7, but not its mutants defectiv

50 PAGR1-deficient cells can be rescued by the ectopic expression of C/EBPbeta or PPARgamma.

51 ion in the inner dental epithelium (IDE) and ectopic expression of calb2 (a TB marker) in these very

52 es driving developmental progression because ectopic expression of catalase, a ROS scavenger, halted

53 Conversely, ectopic expression of catalytically active HDAC5 decreas

54 Notably, ectopic expression of catalytically-inactive RICE1 not o

55 Altogether, our results suggested that ectopic expression of CcFT3 in phloem tissues of Carrizo

56 We found that ectopic expression of CCND1 in multiple human MCL cell l

57 Ectopic expression of Cdh1 leads to premature differenti

58 On ectopic expression of CDX2, these transitional basal pro

59 Furthermore, ectopic expression of Cers2b protein itself reduces acti

60 rentiate, their plasticity is restricted and ectopic expression of CHE-1 no longer results in activat

61 In undifferentiated cells, ectopic expression of CHE-1 results in activation of ASE

62 Ectopic expression of chicken BST-2 blocks the release o

63 Defects upon RetSat depletion are rescued by ectopic expression of ChREBP but not by its putative enz

64 ells removed the restriction for VACV, while ectopic expression of chSAMD9L imposed the restriction f

65 This phenotype was rescued by ectopic expression of Ciona intestinalis alternative oxi

66 d D floral functions, which in turn prevents ectopic expression of class-A genes in ovules for their

67 Ectopic expression of cmo-miR156, using a virus-based mi

68 Ectopic expression of combinations of transcription fact

69 to the host cells, which was validated with ectopic expression of complement receptor 3 (CR3) by CHO

70 mouse beta cell differentiation and induces ectopic expression of crucial delta cell genes, includin

71 Conversely, ectopic expression of CSDE1 impairs neural differentiati

72 Ectopic expression of CsTFL1 rescued the terminal flower

73 Most importantly, the ectopic expression of CX45 significantly enhanced the re

74 Ectopic expression of Cxcl9l recruits mpeg1-positive mac

75 Ectopic expression of DAXX decreased stem/pluripotent ge

76 ene saponins, and extensive but differential ectopic expression of defense response genes.

77 rogrammed into pluripotent stem cells by the ectopic expression of defined transcriptional factors.

78 ts to demonstrate altered transcriptomes and ectopic expression of dental markers in tongue IE.

79 lation and gene expression levels, featuring ectopic expression of developmental transcription factor

80 the major Glut4 PAT, based on evidence that ectopic expression of DHHC7 increased Glut4 palmitoylati

81 Ectopic expression of DHHC7, but not a DHHC7 catalytic m

82 Ectopic expression of different members of the RAS super

83 Notably, ectopic expression of different Merkel cell polyomavirus

84 Ectopic expression of different regions of CteG (656 ami

85 Conversely, ectopic expression of Dmrt1 led to largely masculinized

86 Ectopic expression of DNMT3A(R882mut) and not wild-type

87 Ectopic expression of DOAG1, but not DOAG2, rescues flor

88 Ectopic expression of DOCK6 promoted GC cancer stem cell

89 ed Notch signaling mediated transcription by ectopic expression of dominant-negative mastermind-like

90 te differentiation, which is associated with ectopic expression of downstream targets of RUNX2 in the

91 virus RNA levels, which could be rescued by ectopic expression of DRL-1.

92 hy (FSHD) is an incurable disorder linked to ectopic expression of DUX4.

93 hd-knockdown defects, which were reversed by ectopic expression of EcR.B2 but not by EcR.A or EcR.B1

94 Ectopic expression of EgWRI1-1 in plant produced dramati

95 Ectopic expression of either ePABP or PABPC1 restored Mu

96 mbined genetic SSB1/2 loss can be rescued by ectopic expression of either SSB1 or SSB2, mimicked by e

97 Ectopic expression of EP300-ZNF384 and CREBBP-ZNF384 fus

98 In a new mouse model, ectopic expression of ephrin-A3 (Efna3) in a subset of r

99 uirement for the COP9 signalosome to prevent ectopic expression of Epidermal growth factor receptor (

100 Ectopic expression of ERECTA in the central zone using t

101 Bacterial infection and/or ectopic expression of EspL leads to rapid inactivation o

102 Ectopic expression of EspW results in formation of uniqu

103 inhibited by EZH2 depletion, was rescued by ectopic expression of EZH2 but not by TRIM28 expression

104 ollagen-induced arthritis (CIA) model, while ectopic expression of FGF2 in vivo exacerbated tissue in

105 Ectopic expression of FLL2 increased the size and number

106 Moreover, ectopic expression of GAB1 and GRB2 together with SHP2(D

107 iation of Gene 33 with histone H2AX and that ectopic expression of Gene 33 promotes the interaction b

108 Here we show that ectopic expression of Gene 33 triggers DDR in an ATM ser

109 in regulating GhSOS1 transcript levels, and ectopic expression of GhANN8b elevates Na(+) efflux in A

110 Ectopic expression of GhDsPTP3a and GhANN8b oppositely r

111 Here, we show that ectopic expression of GPR124 promotes cell adhesion, add

112 In this study, we show that ectopic expression of hA3G can prevent the emergence of

113 x2 proteins are enhanced during infection or ectopic expression of HCV core protein.IMPORTANCE Endogl

114 Finally, the ectopic expression of HD5 in tumor cells diminished the

115 Ectopic expression of HIPR-1 mutants demonstrated that n

116 tion in viral RNA, which could be rescued by ectopic expression of HIPR-1.

117 Ectopic expression of HLH-2 and HLH-3 together promoted

118 ed repression of Ealpha is paralleled by the ectopic expression of homeodomain-related oncogenes in T

119 Ectopic expression of Hoxa9 rescued impaired leukemia ce

120 Although ectopic expression of HRAS increased statin sensitivity,

121 rant receptors (HsOrs) responds to CHCs, and ectopic expression of HsOrs in Drosophila neurons impart

122 Ectopic expression of HSP70 relieved suppression of IFN-

123 n cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE2 orthologs fr

124 Likewise, ectopic expression of human THOR in zebrafish accelerate

125 Last, and most surprisingly, ectopic expression of human TMEM2 in C. elegans protecte

126 Third, ectopic expression of IFITMs, known to potently block in

127 duced T cell-mediated pathology, whereas the ectopic expression of IL-27p28 reduced the effector T ce

128 The ectopic expression of ILT3 in CLL was a distinctive feat

129 UB aggregates, which are resolved following ectopic expression of individual GABARAPs.

130 In this study, we demonstrate that ectopic expression of insulin epitope B:9-23 (InsB9-23)

131 Ectopic expression of IRF1 reduced VZV yields 4,000-fold

132 Finally, we found that ectopic expression of IRP2 suppressed cell growth in a m

133 ed sensitive to erythropoietin (Epo) through ectopic expression of its wild-type receptor or a trunca

134 xpression and mouse HL-1 cardiomyocytes with ectopic expression of K2P1 channels recapitulate two lev

135 company cell differentiation, revealing that ectopic expression of KNOTTED1 (KN1) accelerates cell di

136 Finally, in a model of ectopic expression of LAT in ciliated cells, we show tha

137 ced in Lck/Hck/Fgr triple knockout cells and ectopic expression of Lck/Hck/Fgr dampened the antiviral

138 g defects in lefty mutants can be rescued by ectopic expression of lefty far from its normal expressi

139 Consistent with tumor suppressor function, ectopic expression of Leprel1 and Leprel2 inhibits melan

140 ch in mesenchymal nephron progenitors causes ectopic expression of Lhx1 and Hnf1b and that these cell

141 Ectopic expression of lineage master regulators induces

142 Knockdown of LKB1 increased and ectopic expression of LKB1 decreased glycolysis, anchora

143 Finally, we observed that ectopic expression of LmPRL-1 in L. major led to an incr

144 Ectopic expression of LNJ in Arabidopsis resulted in stu

145 Ectopic expression of LRRC25 impaired NF-kappaB activati

146 Functional analyses revealed that ectopic expression of LY6E, but not GILT or ADAP2, in HE

147 Ectopic expression of m153 in fibroblasts augments Clr-b

148 xpression of proliferation-associated genes, ectopic expression of maturation-related genes and persi

149 Impaired CSR can be rescued by ectopic expression of Mbd4 Mbd4 deficiency yields a defi

150 We showed that ectopic expression of miR-1300 led to decreased tumor gr

151 Ectopic expression of miR-15a decreases both mRNA and pr

152 Our observation that ectopic expression of miR-200c triggered apoptosis indic

153 moxifen (TAM)-resistant breast cancer cells, ectopic expression of miR-29b-1/a did not drive TAM-resi

154 Ectopic expression of miR-383 inhibited tumor-initiating

155 Ectopic expression of miR-449a and miR-424 significantly

156 Ectopic expression of miR-K6-5p specifically inhibited t

157 Ectopic expression of MNV receptor (CD300lf) in human HE

158 These effects are measurably rescued by ectopic expression of mouse or human Firre/FIRRE transge

159 Modulation of AKT or HSF1 activity via the ectopic expression of mutant alleles support the ability

160 howed that suppression of SETD2 or CREB1 and ectopic expression of mutant SETD2 conferred cisplatin r

161 sites on target proteins typically requires ectopic expression of mutant SUMOs with introduced trypt

162 Ectopic expression of MYB81 driven by various promoters

163 Moreover, ectopic expression of Myr-Akt1 or phosphomimetic HK2-T47

164 found reduction of ERalpha expression, while ectopic expression of MYST3 had the reversed effect.

165 epithelial to neuroepithelial identity (with ectopic expression of N-cadherin and Sox2), actomyosin d

166 Ectopic expression of N-Myc induced a glycolytic switch

167 eptor Toll-like receptor 11 (TLR11), but the ectopic expression of N. caninum profilin in T. gondii h

168 icient relative to Nef-expressing HIV-1, and ectopic expression of Nef relieves restriction.

169 Consistent with its biochemical function, ectopic expression of Nerfin-1 results in tissue undergr

170 YAC128 HD mouse models through AAV-mediated ectopic expression of NeuroD1 and Dlx2 transcription fac

171 Several earlier studies indicated that ectopic expression of Neurod1 converted non- neuronal ce

172 Consistent with this, loss of sydn-1 blocks ectopic expression of neuronal ankyrin and suppresses ep

173 t from autoimmune responses triggered by the ectopic expression of neuronal proteins in cancer cells.

174 In contrast, ectopic expression of NFI-A in myeloid progenitors from

175 model cystogenesis in vitro, we showed that ectopic expression of NHA2 is causal to increased cyst s

176 Ectopic expression of NHE9 in hBMVECs without external c

177 bal profile of arginine GlcNAcylation during ectopic expression of NleB1, EPEC infection in vitro, or

178 Ectopic expression of non-phosphorylated SNAP-23 mutant

179 Inhibition of Bmp2/4 dorsally caused ectopic expression of Notum, which marks the ventral suc

180 2;5) (p23;q35) translocation, leading to the ectopic expression of NPM-ALK, a chimeric tyrosine kinas

181 onstrate that, in the cells with active p53, ectopic expression of NPRL2 induces NOX2-dependent produ

182 Ectopic expression of NS1 alone did not reduce cyclin B1

183 Correspondingly, ectopic expression of OASL in human cells inhibited IFN

184 eye as a model CNS tissue, here we show that ectopic expression of Oct4 (also known as Pou5f1), Sox2

185 Consistent with this, we found that ectopic expression of oncogenic KRas and HRas in cells r

186 ompanied by aberrant retention of Pol II and ectopic expression of one-cell targets upon major ZGA.

187 While ectopic expression of OPN in the SK-MES-1 lung cancer ce

188 Ectopic expression of OPN4 using a ubiquitous promoter r

189 Mechanistically, we demonstrated that ectopic expression of OSBPL3 facilitates SREBP-1 process

190 Ectopic expression of OtDUB activates Rac1 preferentiall

191 involve dedifferentiation of beta-cells and ectopic expression of other islet hormones, including so

192 Ectopic expression of p205 induced expression of an Asc

193 We demonstrate that the ectopic expression of Pax4 in delta cells is sufficient

194 ated and converted into beta-like cells upon ectopic expression of Pax4 opened new avenues of researc

195 background with a root phenotype resembling ectopic expression of PdBG1, an enzyme that degrades cal

196 Ectopic expression of pdgfaa interferes with cardiac fus

197 was associated with active beta-catenin and ectopic expression of PDLIM2 was sufficient to increase

198 Ectopic expression of PGBD5 in primary immortalized huma

199 Ectopic expression of PGC-1alpha restores mitochondrial

200 Inhibition of Tr-OxPL generation by ectopic expression of PL-specific platelet-activating fa

201 Ectopic expression of PREX1 in cultured human corneal ep

202 Ectopic expression of prolactin receptor in mouse cancer

203 rapidly converted into functional neurons by ectopic expression of proneural transcription factors.

204 This system was validated by ectopic expression of proteins harbouring specific local

205 the EKLF/KLF1 transcription factor leads to ectopic expression of proteins that are not normally exp

206 istration of an oligonucleotide, circumvents ectopic expression of proteins, and represents an attrac

207 ic-biased venous endothelial cells caused by ectopic expression of Prox1, a master transcription fact

208 We also found that ectopic expression of PS improves Arabidopsis resistance

209 Furthermore, ectopic expression of Pt-Ets4 is sufficient to induce ce

210 1 depletion on transcription is mitigated by ectopic expression of R-loop-removing RNase H1.

211 eclinical models of experimental metastasis, ectopic expression of RAGE on human prostate cancer cell

212 However, the ectopic expression of RB1 can suppress cyclin D1 express

213 Ectopic expression of RCP induced Slug expression.

214 Indeed, ectopic expression of repetitive elements enhanced HSPC

215 ucible RGN expression system, we showed that ectopic expression of RGN in prostate tumor cells induce

216 inding by RhCMV strain 68-1 is lost, whereas ectopic expression of Rh05 results in IgG binding to tra

217 The ectopic expression of rice DGAT1 (designated as OsDGAT1-

218 Importantly, ectopic expression of RPL10L prevents the death of cultu

219 Ectopic expression of Runx1 in BFUe lacking a URE fails

220 Ectopic expression of Runx1 or Pu.1, both of which bind

221 Ectopic expression of SbF5H did not affect the gene expr

222 Ectopic expression of SbGPRP1 in tobacco plants led to e

223 Blocking of FGF8 caused ectopic expression of SEMA3C and a migration defect of c

224 ey SHF transcription factor, resulted in the ectopic expression of Sema3c in the pharyngeal arch regi

225 ocked follicle rupture, which was rescued by ectopic expression of shd or exogenous 20E.

226 Furthermore, ectopic expression of sigma3 is sufficient to block IFN

227 and SinR antagonist slrR Deletion of sinR or ectopic expression of slrR in the spermidine-deficient D

228 We demonstrate that ectopic expression of Snai1 in hematopoietic cells predi

229 Ectopic expression of Snail in cancer cell lines lacking

230 Ectopic expression of SNHG6-003 in HCC cells promoted ce

231 However, we observed precocious ectopic expression of Sox2 prior to the 16-cell stage in

232 pre-B cells into macrophages induced by the ectopic expression of specific transcription factors.

233 cells observed might be attributable to the ectopic expression of SPL/NZZ.

234 keratin 5-positive (Krt5(+)) basal cells and ectopic expression of squamous-like differentiation mark

235 Increasing ectopic expression of srtA in the mutant progressively s

236 In contrast, ectopic expression of STAT1, SMCHD1, or PML significantl

237 Ectopic expression of stg is sufficient to suppress G2-s

238 Ectopic expression of TaRca1beta in rice transgenics ind

239 e basis of studies performed in vitro and on ectopic expression of tau in non-neuronal cells.

240 arance of stress-induced aggregates, whereas ectopic expression of TAX1BP1 increases clearance throug

241 iated repression results in upregulation and ectopic expression of tbx2/3, whose expression is normal

242 dels of breast cancer metastasis showed that ectopic expression of TGLI1, but not GLI1, promoted pref

243 Consistent with a gain-of-function effect, ectopic expression of the 2 identified SAMD9L mutants de

244 Furthermore, an ectopic expression of the active Mt-YAP5SA, but not inac

245 Similar observations were made from ectopic expression of the core genomic region from each

246 edirected CD8 T cells to B-cell follicles by ectopic expression of the CXCR5 homing protein.

247 Ectopic expression of the cytosolic, positively charged

248 Ectopic expression of the D-type cyclin induced pavement

249 ss of NQO1 during hypertrophy was rescued by ectopic expression of the distal- but not the proximal-

250 Most notably, we discovered that ectopic expression of the embryonic transcription factor

251 Ectopic expression of the EMT-activating transcription f

252 Tissue-specific GA depletion was achieved by ectopic expression of the GA-inactivating enzyme AtGA2ox

253 infection by bat influenza A virus, whereas ectopic expression of the HLA-DR complex in non-suscepti

254 ovules are morphologically sepaloid and show ectopic expression of the homeotic class-A gene AP1.

255 hed transcripts and the genes upregulated by ectopic expression of the key notochord transcription fa

256 Previously, we showed that ectopic expression of the mitochondrial ribosomal protei

257 dies with patient lymphoblasts and following ectopic expression of the mutant in HEK293 cells.

258 Ectopic expression of the mutated trnE gene uncovered an

259 ells associated with collagen deposition and ectopic expression of the myofibroblastic markers viment

260 Removing an intronic PAS results in ectopic expression of the neuronal ankyrin isoform in no

261 In contrast, ectopic expression of the same chicken Ntn1 in the mouse

262 ectopically expressing wild-type (WT) Brg1, ectopic expression of the SE-Brg1 mutant reduced prolife

263 Ectopic expression of the ubiquitin E3 ligase Parkin, co

264 15 mutant seed was partially rescued through ectopic expression of their direct target EXPA9.

265 Importantly, ectopic expression of this subcircuit was sufficient to

266 ockout cells could be restored completely by ectopic expression of TIM-1 but not TIM-3 or TIM-4.

267 ion of autoreactive T cells by promoting the ectopic expression of tissue-specific genes in the thymi

268 Ectopic expression of TLX3 alone caused partially penetr

269 poietic malignancies and often coincide with ectopic expression of TLX3.

270 Ectopic expression of TOX in effector T cells in vitro i

271 Ectopic expression of TRAF6 promoted the K63-linked ubiq

272 microfluidic peptide array and confirmed by ectopic expression of TRP120 lysine mutants in cells.

273 We show for the first time that ectopic expression of TUBA1A-R402C and TUBA1A-R402H pati

274 channels and mouse HL-1 cardiomyocytes with ectopic expression of two pore-domain K(+) channel isofo

275 Ectopic expression of Ty3 integrase (IN) showed that it

276 Conversely, ectopic expression of UBR7 restored these cellular pheno

277 Ectopic expression of USP17, a cell cycle-dependent deub

278 However, ectopic expression of vascular endothelial growth factor

279 Ectopic expression of VDR in Th9 cells attenuated the pe

280 Together with in vivo ectopic expression of vomeronasal chemoreceptors, PhOTse

281 Remarkably, although ectopic expression of wild-type Beclin1 promoted cardiom

282 Ectopic expression of wild-type Pdcd4 and Pdcd4(157-469)

283 Ectopic expression of wild-type PTEN in PTEN-deficient U

284 ion as it can be significantly attenuated by ectopic expression of WRN.

285 e also required for necroptosis triggered by ectopic expression of ZBP1 and caspase blockade, and ZBP

286 enchymal phenotype, achieved by constitutive ectopic expression of Zeb1, is sufficient to drive cells

287 In contrast, ectopic expression of ZFP521 in HSCs led to a robust mai

288 activation of RMER19B-adjacent genes, while ectopic expression of ZFP708 results in transcriptional

289 Ectopic expression of Zic1 suppressed both lung metastas

290 Ectopic expression of ZIKV NS4B protein results in simil

291 Ectopic expression of ztf-11 in epidermal lineages is su

292 bservations in CRC cell lines indicated that ectopic expressions of miR-378f, -605 and -1976 suppress

293 RASLND overexpression - either via transgene ectopic expression or by endogenous activation via CRISP

294 4S knockdown reduces BRD4S condensation, and ectopic expression promotes puncta formation and target

295 hyperactive in vitro and in cells, and their ectopic expression promotes the proliferation of cancer

296 Following ectopic expression, SCL contributes to oncogenesis in T-

297 PDLIM2 epigenetic restoration or ectopic expression shows antitumor activity, and synergi

298 nd did not conform to the dogma derived from ectopic expression studies.

299 Using knockdown, knockout, and ectopic expression systems, we demonstrate the anti-HSV-

300 In the apum23-4 mutant, MYB23 exhibited ectopic expression that was WER independent and instead