ライフサイエンスコーパス: efface

1 h-eaten," and podocyte foot processes became effaced.

2 y in intestinal cells known as attaching and effacing.

3 intestinal epithelium and produce attach and efface (A/E) lesions, the organism must express the adhe

4 ayers coincident with intimate attaching and effacing (A/E) bacterial adhesion.

5 For the attaching and effacing (A/E) bacterial family member and murine pathog

6 Intestinal infections by attaching and effacing (A/E) bacterial pathogens cause severe colitis

7 Infections by attaching and effacing (A/E) bacterial pathogens, such as Escherichia

8 phenotype, referred to as the attaching and effacing (A/E) effect, is encoded on a 36 kb pathogenici

9 thogens causing characteristic attaching and effacing (A/E) histopathology on intestinal epithelia.

10 (EHEC) is characterized by an attaching and effacing (A/E) histopathology.

11 nses is critical to the success of attaching/effacing (A/E) human pathogenic E. coli (EPEC and EHEC)

12 pathogenic bacteria that cause attaching and effacing (A/E) intestinal lesions.

13 uter membrane proteins involved in attaching-effacing (A/E) lesion formation and host cell invasion b

14 required for the induction of attaching and effacing (A/E) lesion formation characteristic of EPEC i

15 ired for EHEC colonization and attaching and effacing (A/E) lesion formation in the rabbit intestine.

16 ffector protein secretion, and attaching and effacing (A/E) lesion formation in vitro compared to the

17 t necessary for EPEC adherence and attaching/effacing (A/E) lesion formation on human biopsy samples

18 ost gastrointestinal tract via attaching and effacing (A/E) lesion formation.

19 t cells during early stages of attaching and effacing (A/E) lesion formation.

20 g filamentous actin, termed an attaching and effacing (A/E) lesion, directly beneath bound bacteria.

21 Attaching and effacing (A/E) lesions and actin polymerization, the hal

22 ormation of the characteristic attaching and effacing (A/E) lesions by EHEC on epithelial cells, is e

23 iarrhea and enterocolitis with attaching and effacing (A/E) lesions in both the large and small intes

24 ains require intimin to induce attaching and effacing (A/E) lesions in newborn piglets.

25 cherichia coli (EPEC) produces attaching and effacing (A/E) lesions in the intestinal mucosa.

26 The formation of attaching and effacing (A/E) lesions is central to the pathogenesis of

27 i (EPEC) induce characteristic attaching and effacing (A/E) lesions on epithelial cells.

28 diarrheal pathogen that causes attaching and effacing (A/E) lesions on intestinal epithelial cells.

29 s the ability of EPEC to cause attaching and effacing (A/E) lesions on intestinal epithelium.

30 EC) infection are formation of attaching and effacing (A/E) lesions on mucosal surfaces and actin-ric

31 O127:H6 but is unable to form attaching and effacing (A/E) lesions or to secrete Esp proteins when i

32 retion system (T3SS) to induce attaching and effacing (A/E) lesions that are essential for virulence.

33 psy samples by forming typical attaching and effacing (A/E) lesions which are dependent on EHEC type

34 tinal epithelial cells induces attaching and effacing (A/E) lesions, alters intestinal ion transport,

35 not only induce characteristic attaching and effacing (A/E) lesions, but also subvert multiple host c

36 the intestine via formation of attaching and effacing (A/E) lesions.

37 ttachment and the formation of attaching and effacing (A/E) lesions.

38 lf to enterocytes and induces attachment and effacing (A/E) lesions.

39 nd disrupts microvilli to form attaching and effacing (A/E) lesions.

40 The attaching and effacing (A/E) pathogen enteropathogenic Escherichia col

41 The diarrheic attaching and effacing (A/E) pathogen Escherichia albertii was first i

42 Attaching and effacing (A/E) pathogens adhere intimately to intestinal

43 and a model for the family of attaching and effacing (A/E) pathogens.

44 nse to intestinal infection by attaching and effacing (A/E) pathogens.

45 nal mucosa in a characteristic attaching and effacing (A/E) pattern, which is mediated by the bacteri

46 is unique to EPEC and related "attaching and effacing" (A/E) pathogens, plays a role in limiting host

47 ystem and to be essential for 'attaching and effacing' (A/E) lesion formation, the hallmark of EPEC p

48 iated intimate attachment and 'attaching and effacing' (A/E) lesion formation.

49 ological feature known as the 'attaching and effacing' (A/E) lesion.

50 Attaching and effacing activity is associated with the accumulation of

51 pF mutant was not deficient in attaching and effacing activity or invasion capacity.

52 lusively in strains capable of attaching and effacing activity.

53 tant strain of EPEC to restore attaching and effacing activity.

54 d protein that is required for attaching and effacing activity.

55 ogic nodular growth in the portal triad that effaced adjacent hepatic parenchyma.

56 Attaching and effacing (AE) bacteria are a diverse group of gastrointe

57 li (EHEC) serotype O157:H7, an attaching and effacing (AE) food-borne pathogen that causes severe gas

58 m-negative bacteria that cause attaching and effacing (AE) intestinal lesions.

59 Attaching and effacing (AE) lesion formation on enterocytes by enterop

60 n, effector translocation, and attaching and effacing (AE) lesion formation on enterocytes, but the m

61 fore central to the process of attaching and effacing (AE) lesion formation.

62 facement (LEE) responsible for attaching and effacing (AE) lesion formation.

63 on epithelial cells called the attaching and effacing (AE) lesion.

64 g filamentous actin, termed an attaching and effacing (AE) lesion.

65 m (T3SS), causing the hallmark attaching and effacing (AE) lesions and actin-rich pedestal formation

66 bacteria, some of which cause attaching and effacing (AE) lesions and enteritis in humans and animal

67 thogenesis is the formation of attaching and effacing (AE) lesions on colonic epithelial cells.

68 toxins (Stx) and formation of attaching and effacing (AE) lesions on intestinal epithelial cells.

69 he large intestine, EHEC forms attaching and effacing (AE) lesions on intestinal epithelial cells.

70 mpanies increased formation of attaching and effacing (AE) lesions requisite for EHEC colonization.

71 lved in type III secretion and attaching and effacing (AE) lesions.

72 s the large intestine, causing attaching and effacing (AE) lesions.

73 s an ANR homolog identified in attaching and effacing (AE) pathogens, including Citrobacter rodentium

74 equired for the characteristic attaching and effacing (AE) pathology seen in infection with these thr

75 al epithelium, EHEC generates "attaching and effacing" (AE) lesions characterized by intimate attachm

76 pithelioma in which teratoid rhabdomyoblasts effaced all but trace amounts of neuroepithelium and gen

77 end of the LEE is required for attaching and effacing and reveal information relevant to the origin a

78 d to identify enterotoxigenic, attaching and effacing, and Shiga toxin-producing Escherichia coli str

79 By infecting mice with the attaching and effacing bacteria Citrobacter rodentium, we defined the

80 Defense against attaching-and-effacing bacteria requires the sequential generation of

81 t models human infections with attaching-and-effacing bacteria.

82 odel for human infections with attaching and effacing bacteria.

83 l and represent the only known attaching and effacing bacterial pathogen of mice.

84 rrhagic Escherichia coli and other attaching/effacing bacterial pathogens cause diarrhea in humans.

85 innate immune response to the attaching and effacing bacterium Citrobacter rodentium.

86 with Citrobacter rodentium, an attaching-and-effacing bacterium that provokes innate and adaptive imm

87 munity against this intestinal attaching and effacing bacterium.

88 immigrants presented with significantly more effaced basilar cisterns (p = 0.0008).

89 ere intimately to intestinal enterocytes and efface brush border microvilli.

90 all cases, the lymph nodes were involved and effaced by an atypical polymorphous lymphoid proliferati

91 ected IFN-gamma-deficient mice is completely effaced by expansion of macrophages, granulocytes, and e

92 gnals; 3) seb1-G476S derepression of pho1 is effaced by loss-of-function mutations in cleavage and po

93 Rad24 function in repressing pho1 was effaced by mutation of its phosphate-binding pocket.

94 e negative effect of parasitism seemed to be effaced by predation.

95 ded coarse, granular canalicular Byler bile, effaced canalicular microvilli, and proliferative perica

96 em required for characteristic attaching and effacing changes that modify the cytoskeleton and apical

97 r rodentium, a murine model of attaching and effacing diarrheagenic Escherichia coli, we demonstrate

98 and lpfA2 genes from different attaching-and-effacing E. coli strains has led us to the identificatio

99 rence in adaptive responses by attaching and effacing E. coli.

100 r of EPEC, is required for the attaching and effacing effect characteristic of EPEC and enterohemorrh

101 a process that is known as the attaching and effacing effect.

102 the mutant fails to induce the attaching and effacing effect.

103 face in a process known as the attaching and effacing effect.

104 dels human infections with the attaching and effacing enteropathogenic and enterohaemorrhagic Escheri

105 A cells were infected with the attaching and effacing enteropathogenic Escherichia coli (EPEC).

106 al isolate from a patient with attaching-and-effacing enteropathy displayed the localized adherence a

107 The attaching and effacing Escherichia coli (AEEC) are characterized by th

108 Attaching and effacing Escherichia coli (AEEC) strains are a genomical

109 ns with either parvovirus (n = 1), attaching-effacing Escherichia coli (n = 4), or protozoan parasite

110 Attaching and effacing Escherichia coli cause diarrhea and typically p

111 inant of AF/R1 pilus production in attaching/effacing Escherichia coli RDEC-1 and identified seven ge

112 s a 366 kDa protein expressed by attaching & effacing Escherichia coli.

113 ed a prominent development of disordered and effaced foot processes, upregulation of renal injury and

114 BNT2 regulated the E. coli attaching and effacing gene-positive conserved fragments 1-4 (ecf1-4)

115 ed that the pO157 ecf (E. coli attaching and effacing gene-positive conserved fragments) operon is th

116 itrobacter rodentium causes an attaching and effacing infection of the mouse colon.

117 coli (EHEC) O157:H7 that mediate attach and efface intestinal lesions are classified as intimin alph

118 EC strains were the absence of attaching and effacing intestinal lesions in pigs inoculated with non-

119 sease but colonized and caused attaching-and-effacing intestinal lesions.

120 ) and is necessary for causing attaching and effacing intestinal lesions.

121 no acids that contact the guanine nucleobase efface kinase activity in vitro and Trl1 function in viv

122 nes for Shiga toxin(s) and the attaching-and-effacing lesion (stx1, stx2, and eae), suggesting their

123 and for the development of the attaching and effacing lesion characteristic of EPEC infection.

124 An orfU mutant was defective in attaching-effacing lesion formation and Tir secretion, but was una

125 ated receptor (Tir) to promote attaching and effacing lesion formation during infection with enteropa

126 vely and qualitatively typical attaching and effacing lesion formation in intestinal epithelial cells

127 motility, oxidative stress and attaching and effacing lesion formation, which contribute to EHEC colo

128 unction without involvement in attaching and effacing lesion formation.

129 ization, organ specificity, or attaching and effacing lesion formation.

130 ga-like toxin types I or II or the attaching-effacing lesion genes.

131 ciated with the characteristic attaching and effacing lesion in colonic tissue sections and produced

132 ure cells and formation of the attaching and effacing lesion in the gnotobiotic pig.

133 The attaching and effacing lesion is encoded by the Locus of Enterocyte Ef

134 teins cause the characteristic attaching and effacing lesion on enterocytes.

135 Enteric infections with attaching/effacing lesion-inducing bacterial pathogens are a world

136 eventing systemic dissemination of attaching/effacing-lesion forming bacterial pathogens such as C. r

137 cherichia coli (EPEC) produces attaching and effacing lesions (AE) on epithelial cells.

138 , is required for formation of the attaching-effacing lesions and for full pathogenesis of the bacter

139 volved in the formation of the attaching and effacing lesions by enterohemorrhagic Escherichia coli (

140 exneri and to the formation of attaching and effacing lesions by enteropathogenic Escherichia coli.

141 necessary for the formation of attaching and effacing lesions by EPEC.

142 a coli to cause characteristic attaching and effacing lesions in host cells.

143 istant adherence, but produced attaching and effacing lesions in the absence of mannose on cultured H

144 ic Escherichia coli to produce attaching and effacing lesions in the distal colon of mice.

145 pigs had a lower frequency of attaching and effacing lesions in the spiral colon than parent strain-

146 tor necessary for formation of attaching and effacing lesions on epithelial cells), were directly reg

147 coli (EHEC) O157:H7 to produce attaching and effacing lesions on host cells.

148 and EPEC) infections result in attaching and effacing lesions on intestinal epithelial cells.

149 filled membranous protrusions (attaching and effacing lesions) that form on the surface of mammalian

150 and tir did not colonize, form attaching and effacing lesions, or develop clinical signs of disease.

151 ADB secretion, or formation of attaching and effacing lesions.

152 ctin, which is associated with attaching and effacing lesions.

153 zes the gut mucosa and induces attaching-and-effacing lesions.

154 nic E. coli were evaluated for attaching and effacing lesions.

155 the formation of distinctive 'attaching and effacing' lesions.

156 The attaching and effacing mouse pathogen Citrobacter rodentium associates

157 hway and for full virulence of the attaching/effacing mouse pathogen Citrobacter rodentium.

158 Citrobacter rodentium is an attaching and effacing mouse pathogen that models enteropathogenic and

159 The process exposes the effaced mucosa and sphincter to acid gastric juice.

160 Within several hours, MZ were completely effaced of affected B cells.

161 This mutant is incapable of attaching and effacing, of secreting EspA and EspB and of inducing tyr

162 nd studied DC responses to the attaching and effacing pathogen Citrobacter rodentium in these.

163 lenges, we employed the murine attaching and effacing pathogen Citrobacter rodentium, which colonizes

164 ) and analyzed immunity to the attaching-and-effacing pathogen Citrobacter rodentium.

165 itrobacter rodentium, a murine attaching and effacing pathogen related to EPEC.

166 virulence factors of an intestinal attaching/effacing pathogen, bind to bacteria localized at the epi

167 egulator, RegA, from the mouse attaching and effacing pathogen, Citrobacter rodentium, as a potential

168 ates against infection with an attaching and effacing pathogen.

169 ment (LEE) is found in diverse attaching and effacing pathogens associated with diarrhea in humans an

170 er rodentium are classified as attaching and effacing pathogens based on their ability to adhere to i

171 er rodentium are classified as attaching and effacing pathogens based on their ability to adhere to t

172 NleB is conserved among the attaching/effacing pathogens enterohemorrhagic Escherichia coli (E

173 -1 with those from a number of attaching and effacing pathogens infecting different species and of di

174 Attaching and effacing pathogens overcome colonisation resistance by c

175 sential for the persistence of attaching and effacing pathogens such as enteropathogenic Escherichia

176 ss the antimicrobial response, attaching and effacing pathogens use type III secretion systems to int

177 e canonical virulence trait of attaching and effacing pathogens.

178 st-translational regulation in attaching and effacing pathogens.

179 controls the timing of T3S in attaching and effacing pathogens.

180 naling in infections caused by attaching and effacing pathogens.

181 played the localized adherence attaching-and-effacing pattern typical of enteropathogenic E. coli on

182 omeruli in EMCN(-/-) mice revealed fused and effaced podocyte foot processes and disorganized endothe

183 were seen in Alport GBM thickenings beneath effaced podocyte foot processes, but morphologically nor

184 a thickened glomerular basement membrane and effaced podocytes in the diabetic WT mice, these changes

185 thelial cells within glomerular capillaries, effaced podocytes with extremely wide foot processes and

186 ith increased fibrosis, proteinaceous casts, effaced podocytes, and loss of the slit diaphragm.

187 RDEC-1 (serotype O15) is an attaching and effacing strain of rabbit enteropathogenic Escherichia c

188 er cells with the ability to proteolytically efface the BM scaffolding, initiate the assembly of inva

189 proliferation of atypical granulocytes that efface the bone marrow and result in severe tissue destr

190 cific inhibitors (vemurafenib or dabrafenib) effaces the peculiar morphologic, phenotypic, and molecu

191 ment of conflicts along partisan lines, thus effacing the counterbalancing effects of local heterogen

192 Trilobate morphology and effaced transverse furrows are locally evident, but the

193 the espB gene are required for attaching and effacing, we constructed a mutant with an omega-interpos

194 growing body of evidence and experience has effaced what were once thought to be clear distinctions