ライフサイエンスコーパス: efficient

1 ing PrEP services accessible, simplified and efficient.

2 vin per oral supplementation is often highly efficient.

3 ny of Aedes aegypti mosquitoes was similarly efficient.

4 eased porosity due to sonication allowed the efficient absorption of folic acid into the brown rice k

5 An efficient access to 6-substituted 7-deazapurine and the

6 oboration and boron-Wittig reactions, a new, efficient access to cyclic 1,3-dienyl boronic esters has

7 ntioselective C(sp(3))-H aminations allow an efficient access to nonracemic chiral amines.

8 This efficient algorithm is an extension of the k-means algor

9 With a computationally efficient algorithm, which is based on penalized quasi-l

10 robust statistical methods and fast, memory efficient algorithms, to quickly, accurately and reliabl

11 oamines to give aminium radicals that enable efficient alkene aminochlorination.

12 Computationally efficient all-atom structure-based simulations, calibrat

13 over the past few years as a computationally efficient alternative to time-consuming and computationa

14 Rapid-set liquid bandages are efficient alternatives but lack durability or inherent i

15 nt and cancerous cells, this approach allows efficient analysis of aged and cancerous cell-specific D

16 diting systems, enCRISPRa and enCRISPRi, for efficient analysis of enhancer function in situ and in v

17 sent a novel method, Metalign, that performs efficient and accurate alignment-based metagenomic profi

18 tion for the resulting complex, providing an efficient and broadly applicable approach to early fragm

19 omplex, a base and a boryl compound, promote efficient and controllable alkene transposition.

20 The process relies on the efficient and controlled reduction of tertiary amides by

21 n of PrEP use among cisgender MSWs may be an efficient and cost-effective strategy for reducing HIV i

22 irming that our computational approach is an efficient and cost-effective tool for drug target discov

23 This approach has proven to be an efficient and cost-effective way to identify efficacious

24 The demonstration of energy efficient and high-speed electro-optic modulation at the

25 scope to promote the development of robust, efficient and highly selective LRSPR based biosensors wi

26 Exploring efficient and low-cost electrocatalysts for hydrogen evo

27 and mild conditions make our procedure more efficient and practical for organic synthesis.

28 rRuO(3) as a model system, we demonstrate an efficient and reversible control of both structural and

29 ing application of BO in CNT synthesis as an efficient and robust algorithm which can (1) improve the

30 ll is necessary as the range of pressure for efficient and safe BBB opening is very narrow.

31 For efficient and safe delivery to cancer cells, nucleic aci

32 16S Capture provides a novel means for the efficient and sensitive detection of bacteria embedded i

33 Efficient and specific drug delivery to the BM is an unm

34 of charged amino acids with a catalytically efficient and thermodynamically favorable diol formation

35 s of Whole Genomes (PCAWG) project in a time-efficient and uniform manner.

36 health efforts; it is fast, robust, and cost-efficient, and generates full genomic sequences of diver

37 tion of large sample cohorts requires rapid, efficient, and highly reproducible sample preparation.

38 elopment that prepares the organ for strong, efficient, and persistent pumping throughout the mammal'

39 We show that cnCV is an effective and efficient approach for combining feature selection with

40 An automated, time-efficient approach for extracting and grading eMS is pos

41 ncing of genomic regions is a cost- and time-efficient approach for screening patient cohorts.

42 Energy-efficient approaches to propylene/propane separation suc

43 We present computationally efficient approximants that estimate stationary single-c

44 Nonetheless, flexible electronics are not as efficient as silicon ICs for computation and signal comm

45 duce a comprehensive method that enabled the efficient assembly of a high-quality and diverse library

46 oupling approaches, we present here a highly efficient asymmetric intermolecular Ni-catalyzed reducti

47 ient at cell-free spread but is particularly efficient at cell-to-cell spread, whereas TB and TR cell

48 ymes to develop RNA switches that are highly efficient at cis-cleaving mammalian mRNAs and showed tha

49 AFFF formulations were less efficient at lowering interfacial tension than PFOA, FPO

50 c guanidinylated peptides, which catalyze an efficient atroposelective chlorination, is reported for

51 These results establish a novel, efficient B cell-dependent EAE model.

52 Efficient base editing requires cellular exposure to lev

53 vestigations for the development of safe and efficient biological control programs.

54 hanism by which the solvent components drive efficient biomass breakdown.

55 A concise and efficient bottom-up methodology was employed during whic

56 rocessing capability is imperative to deploy efficient brain-like vision systems.

57 ied and remarkable functionalities, becoming efficient building blocks for the construction of molecu

58 e structural characteristics responsible for efficient C-C formation is restricted by the intrinsic a

59 miRNAs are considered efficient candidate biomarkers due to their high stabili

60 tyryl)taxol side chain), TmAAE15 as a highly efficient candidate for hexanoic acid activation (Taxol

61 osition of P12(1) /c1-type K(2) CO(3) at the efficient carbon-based catalyst.

62 Here we describe a platform for efficient Cas12a gene editing in Drosophila We show that

63 otein film electrochemistry to determine how efficient catalysis depends on the long-range coupling o

64 te undergoes which align the nucleophile for efficient catalysis.

65 BN) has recently been identified as a highly efficient catalyst for the oxidative dehydrogenation of

66 The copper hydride complexes are efficient catalysts for the dehydrogenation of formic ac

67 e latter showing excellent promise as highly efficient catalysts under inert atmosphere conditions.

68 l, we confirmed that iron salts are the most efficient catalysts.

69 MHV infection in mice provides an efficient cause-effect experimental model to understand

70 bles the complete removal of cell-free RNAs, efficient cell lysis and mRNA capture, achieving highest

71 ed for full activation of the GTPase and for efficient cell migration.

72 traps and engineered a protocol allowing for efficient chemical exchange for hundreds of C. elegans e

73 Reversible catalysis is a hallmark of energy-efficient chemical transformations, but can only be achi

74 B. minax interacts with plant hosts via the efficient chemosensory system.

75 etrained on Fourier spectrum features allows efficient classification of electrograms recordings as A

76 According to the efficient coding hypothesis, sensory systems are adapted

77 Efficient communication between heart cells is vital to

78 ans-eQTL of the target gene but also enables efficient computation by using summary statistics from s

79 Collectively, we develop an efficient computer program package, gamevar.f90, for est

80 tors for short) are nature's solution to the efficient conversion of chemical energy to mechanical mo

81 This work shows that efficient conversion of CO(2) to C(2+) products requires

82 widely distributed methane resources require efficient conversion of methane into liquid chemicals, w

83 Scalable, efficient conversion of radiated waste heat into electri

84 Carriers of this FOLH1 variant had less efficient cortical activity during working memory.

85 odynamic, or other focusing units to produce efficient counting which could allow for dramatically in

86 Efficient coupling of a range of electronically and ster

87 as a flexible molecular spacer that ensures efficient coupling of the SNAP25-zDHHC17 interaction and

88 nt interactions couple productive binding to efficient deacetylation of histones on endogenous chroma

89 a clinically relevant model system, we show efficient degradation by noncovalent, irreversible coval

90 ocarbon nanoemulsions (PFCs) resulted in the efficient delivery of (19)F cargo to EpiSCs and enabled

91 or the development of this technology is the efficient delivery of RNAi effectors into the cell.

92 Phactr1/PP1 surface, which are required for efficient dephosphorylation.

93 y data, we discuss emerging features for the efficient deployment of novel TCR-T therapies, such as s

94 e this gap, we propose a method for fast and efficient deposition of variety of molecules (e.g. prote

95 ro-macro approach for the identification and efficient design of biopolymer stabilized soil systems.

96 guided modes by the electron beam and their efficient detection via photons emitted in the ribbon pl

97 aneous polarization and are promising energy-efficient device components for digital information stor

98 ds and sense of stereoinduction for the most efficient diether and amino ether ligands prove to be fo

99 Less efficient digestion leads to a lower BMF(lim) in a juven

100 context of lagging strand DNA synthesis, the efficient disruption of a nucleosome barrier by Pif1 cou

101 e barriers are expected to pose a problem to efficient DNA bubble migration.

102 The conjugation is efficient, does not compromise the affinity of the paren

103 g conjugate by trans-cyclooctenes, affording efficient drug liberation in plasma and cell culture.

104 he systems facilitate tightly controlled and efficient DSB formation at defined genomic sites and wil

105 Because an HPM is incompatible with efficient dynamic programming alignment algorithms, we d

106 osis and treatment of AKI due to the lack of efficient early diagnosis is an important cause of its h

107 e studies suggest that EBNA3A contributes to efficient EBV-induced lymphomagenesis in CBH mice.IMPORT

108 tently infected B cells and is important for efficient EBV-induced transformation of B cells in vitro

109 solubility, high first-pass metabolism, and efficient efflux by P-glycoprotein.

110 ise, no noise is intrinsically introduced by efficient electro-optic modulation via a sum-frequency-g

111 Selective, efficient electrocatalysts that operate at low temperatu

112 d a favourable electronic band structure for efficient electron charge transport.

113 ate that TCP14 and TCP15 are required for an efficient elongation response to auxin, most likely by r

114 oposed hierarchical model by implementing an efficient EM algorithm.

115 An efficient, enantio- and diastereoselective, copper-catal

116 alent self-assembly approach, we demonstrate efficient encapsulation of medium to large proteins (HRP

117 documented in perception, where it supports efficient encoding over a broad range of possible percep

118 ery rapid (picosecond time scale) and highly efficient energy transfer (around 90% efficiency), as ev

119 Efficient energy transfer is particularly important for

120 Efficient engagement with the envelope glycoprotein memb

121 cent modules in either ring to be active for efficient enzyme function.

122 This highly efficient enzyme preparation combines enzyme immobilizat

123 We identified TmAAE1 and TmAAE5 as the most efficient enzymes for the activation of butyric acid (Ta

124 packages R-INLA and glmmTMB, we hope to make efficient estimation of RSFs and SSFs with random effect

125 our understanding of the factors that favor efficient excision is limited by the lack of a rapid, ac

126 simulations, potentially paving the way for efficient exploration of additional active flow control

127 Collectively, our results highlight efficient fibroblast rejuvenation through laterally conf

128 a, whereas cpRNFL thickness remains the most efficient for advanced glaucoma.

129 While the text based format of ped files is efficient for computational methods, it is not immediate

130 The STEP-KOA strategy may be efficient for delivering exercise therapies for knee ost

131 Moreover, this technique was efficient for inactivating polyphenoloxidase.

132 wer spatial frequencies, and as such is more efficient for phase recovery than conventional phase con

133 the immobilized biocatalyst was shown to be efficient for pomegranate juice fermentation, as indicat

134 -red biosensors as a FRET acceptor and is an efficient FRET donor that supports red/far-red FRET bios

135 An ideal tool for gene therapy would enable efficient gene integration at predetermined sites in the

136 ge on the available diversity due to lack of efficient germplasm characterization and structure.

137 hobic host cell surfaces, and contributes to efficient gut colonization and host infection.

138 xyl polymer doping thus offers a pathway for efficient H doping in green solvent-processed metal oxid

139 Moreover, we propose an efficient hardware design for clinically viable iBCIs, a

140 als with latent Mtb infection supported more efficient HIV-1 transcription, release, and replication.

141 ials have become better regulated and energy efficient homes may reduce ventilation.

142 FANCD2 deubiquitination, it is required for efficient HR-mediated chromosome damage repair.

143 orrelated binomial distribution to create an efficient hypothesis testing algorithm that identifies b

144 tion of Irf4 in CD11c(+) DCs results in more efficient immune control of Helicobacter pylori, Mycobac

145 Mix23 is critical for the efficient import of proteins into the mitochondrial matr

146 ndicate that the proposed 2SigFinder is more efficient in identifying genomic islands.

147 Detoxification of iAs was much less efficient in the humanized mice than in wild-type mice.

148 rial topoisomerase I enzymes that are highly efficient in their physiological role of preventing exce

149 ive multidisciplinary approach to develop an efficient, inexpensive, and easy-to-use portable instrum

150 , we show that this activity is required for efficient infection by SBV.

151 tein carried in the virion, is important for efficient infection of primary macrophages.

152 the class-II Hsp40, human DNAJB6b, a highly efficient inhibitor of protein self-assembly in vivo and

153 rgeted knock-ins at eight zebrafish loci and efficient integration at safe harbor loci in porcine and

154 -density lipoprotein) particles could act as efficient intermediate acceptors of cellular-derived UC,

155 The supramolecular polymer ensures the efficient intracellular delivery and the release of Cas9

156 e used for base-broadening breeding aimed at efficient introgression of desirable alleles.

157 OF channels for selective ion conduction and efficient ion separation.

158 versity of this complex mixture prevents the efficient ionization of the organic material by a single

159 paramount importance in order to facilitate efficient isolation, characterization, and quantitation

160 reference-free assembly evaluation based on efficient k-mer set operations.

161 resentation of single-cell data that enables efficient large-scale computations.

162 choice-confirmation bias may be adaptive for efficient learning of action-outcome contingencies, abov

163 The efficient ligand-based design approach adopted demonstra

164 s continues to be a challenging endeavor and efficient ligand-receptor systems need to be identified.

165 ed to test the efficacy of these drugs in an efficient manner with respect to time, cost, and patient

166 space that encodes the given data in a more efficient manner, followed by a decoding network through

167 l audits, financial penalties and rewards to efficient maternity centres could also be considered.

168 TooManyCells is also equipped with an efficient matrix-free divisive hierarchical spectral clu

169 Such early filtering may provide an efficient means of optimizing central visual processing

170 erting chemical and light energy inputs into efficient mechanical work.

171 nc-imidazole frameworks (ZIF-4), as a highly efficient media for on-line separation of phenolic acids

172 d promises to empower transformative, energy-efficient memory technology.

173 ing complete glucagon-mediated responses and efficient metabolic adaptation to fasting in vivo.

174 Efficient metastasizers had higher levels of MCT1, and i

175 rned from bulk measurements, establishing an efficient method for surveying cell populations from lar

176 Previously, we developed an efficient method for the simultaneous quantification of

177 A facile and efficient method for the synthesis of 3-[(4-nitrophenyl)

178 ous, OCT-derived measurements may provide an efficient method of objectively quantifying the pupil re

179 atform for chemo-drug delivery as well as an efficient method to solubilize hydrophobic drugs.

180 bered nitrogenous heterocyclic scaffolds, an efficient method, employing 2-aminoaryl N-monosubstitute

181 us scaffolds in many areas of chemistry, and efficient methods for their synthesis are continually de

182 many natural systems, and the development of efficient methods to understand and accurately predict s

183 ly fuels proper mtLSU maturation by securing efficient methylation of two 16S rRNA residues, and ulti

184 further restricting motility and preventing efficient migration of microglia to sites of neuronal da

185 The results demonstrated a simple but efficient misannotation detection approach that is usefu

186 ng dominant drivers is crucial for designing efficient mitigation policies.

187 use and build upon with the goal of enabling efficient model building, sharing, and reproducibility.

188 This highly efficient multiplex CRISPR/Cas9_Trex2 system makes it po

189 endogenous DNA gap repair in E coli supports efficient multiplex site-directed mutagenesis.

190 ts, with recruited MPs being responsible for efficient myelin stripping and clearance and resident MP

191 This efficient navigational strategy has never been demonstra

192 combining metal-oxide WD catalysts that are efficient near the acidic proton-exchange layer with tho

193 the acidic proton-exchange layer with those efficient near the alkaline hydroxide-exchange layer, we

194 Here, we describe a rare case of highly efficient near-cognate initiation.

195 An efficient new synthesis of 3,5-bis(het)arylisoxazoles, i

196 ffectively replaces a DNA repair protein for efficient NHEJ with implications for development of resi

197 777) ignore the reported efficient Ni/MgO solid-solution catalysts and overstate

198 guide losses that prevent the realization of efficient nonlinear processes on-chip.

199 , a major human-specific pathogen, relies on efficient nutrient acquisition for successful infection

200 A simple but efficient one-pot or sequential copper-catalyzed protoco

201 nism whereby lesion discrimination relied on efficient opening versus diffusion.

202 Our work demonstrates efficient optical metamaterial engineering based on stru

203 ction of the likelihood calculation time for efficient parameter determination.

204 Using these reactions, highly efficient pathways to 2-arylquinolines and 2-aryl-3-trif

205 We report a straightforward and efficient Pd/enamine catalytic procedure for the direct

206 , ZnCl(4) , ZnCl(2) Br(2) , ZnBr(4) ), from efficient phosphorescence to ultralong afterglow.

207 Cost-effective bacterial RNA-seq requires efficient physical removal of ribosomal RNA (rRNA), whic

208 tanding of rational design concepts for more efficient polarizing agents (PAs).

209 eases of gene-drive males robustly result in efficient population modification with >=95% of mosquito

210 n in larger cohorts, SHIFT could serve as an efficient preliminary, auxiliary, or substitute for panC

211 bic ammonium oxidation) represents an energy-efficient process for biological nitrogen removal, parti

212 isopropanol (50/50) was found to be the most efficient process, producing high carotenoids content an

213 A flexible and efficient R package is needed for analyzing processed mu

214 ant inhibition of several CYPs, demonstrated efficient RBC partitioning and high membrane permeabilit

215 P2RX7 was required for efficient re-expression of the receptor TGF-betaRII thro

216 1/H6 plays an important role in facilitating efficient reactivation from latency.IMPORTANCE While HSV

217 ional neural code potentially contributes to efficient reading.

218 However, performing efficient reagent exchange on chip for large numbers of

219 g capacity of PSI is largely due to the more efficient recruitment of LHCII already residing in the s

220 is feature stems mainly from two mechanisms: efficient recruitment of mDia1 to SPIN90-Arp2/3 nucleate

221 ing wound-induced proliferation required for efficient regeneration.

222 rosine kinase Src as a model, we demonstrate efficient regulation of the kinase and identify temporal

223 enzymes rather than LPCAT mediate the highly efficient removal of HFA from PC in castor seeds.

224 le HA protein (pH 5.5-5.6) was necessary for efficient replication and airborne transmission.

225 via a network of interactions important for efficient replication fork pausing.

226 fect on HIV-1 replication, allowing for more efficient replication while potentially contributing to

227 to clear the template of ribosomes to allow efficient replication.

228 ase of the amplitude of precession indicates efficient resonant heat transfer from the lattice to coh

229 Further, sw/OH/2017 was capable of efficient respiratory droplet transmission from infected

230 Drawing on ideas from information theory, an efficient retinal code could be defined as one that redu

231 AAV2.retro, a new capsid variant capable of efficient retrograde transport in brain, was generated i

232 e tethered while they bud, thereby promoting efficient retrograde transport.

233 Efficient reuptake of the inhibitory neurotransmitter GA

234 Efficient routes to their production and processing have

235 aenorhabditis elegans COQ-2e is required for efficient RQ synthesis and survival in cyanide.

236 Efficient S phase entry is essential for development, ti

237 In particular, mammalian mesopredators are efficient scavengers that are often subjected to control

238 ut damaging the SERS substrate, allowing for efficient sensor reuse.

239 ified by previous experience is critical for efficient sensory processing and improved behavioral out

240 Th-metal-organic framework (MOF) for highly efficient separation of C(2)H(4) from a binary C(2)H(6)/

241 Herein, the efficient serotonin (5-HT) sensing studies have been con

242 chy in human societies, and, by providing an efficient short-cut to acquiring adaptive information, u

243 a new myelin imaging technique based on time-efficient simultaneous T(1) /T(2) relaxometry and proton

244 enable the identification of the full set of efficient solutions (supported and unsupported) to the m

245 This study point to soft bread as a safe and efficient source of melanoidins, that could be potential

246 ents is spatiotemporally regulated to ensure efficient spindle assembly remains unclear.

247 ated by hnRNP K, a host protein required for efficient splicing of the IAV M transcript in nuclear sp

248 t5 files, which must be compressed to enable efficient storage and transfer.

249 arizes the challenges in the path towards an efficient strain construction and highlights the genomic

250 This work presents an efficient strategy which can lead to time and cost savin

251 squitoes' ecological role, and the design of efficient sugar-baited traps will all benefit from under

252 In this manuscript, a simple and efficient sulfa-Michael addition reaction of aryl thiols

253 Efficient sulfate diester formation was achieved through

254 ispersion will benefit future design of more efficient supported Ag catalysts.

255 his emerging approach also demonstrates that efficient surface ligand engineering can exploit the uni

256 Reproductive performance is critical for efficient swine production.

257 In this study, we established a highly efficient synchronization method for G2/M phase of sheep

258 V) mediated cross-coupling amendable for the efficient synthesis of heteroaromatic substrates.

259 An efficient synthetic approach to the tricyclic 1,7a-dihyd

260 A facile efficient synthetic tool, Buchwald-Hartwig cross-couplin

261 d may contribute to the generation of a more efficient system for precise gene integration in catfish

262 cancer-specific gene expression facilitates efficient targeted therapies and treatment strategies.

263 esults may be beneficial in identifying more efficient, targeted recovery approaches to improve athle

264 regression-based machine learning models are efficient techniques for mapping land susceptibility to

265 grates several cutting-edge, computationally efficient techniques with other Python packages (e.g., N

266 BPSs are a labor and cost-efficient technology but are still mainly operated as bl

267 rly cancer detection and holds promise as an efficient test for low-cost rollout to clinics.

268 It is faster and more efficient than current tools and can be easily integrate

269 em authentication on cheese samples was less efficient than on milk, but still possible.

270 imulant, has proved to be significantly more efficient than TBP and ExBox(+4) , confirming the import

271 5 times more precise, and was 3-8 times more efficient than the staircase method.

272 th activated arabinonucleotides is much less efficient than with activated ribonucleotides, and furth

273 ugh most of the current therapies are mostly efficient, the side effects can result in therapy stop,

274 The exo-adamantyl groups give rise to a more efficient threading with respect to the exo-tert-butyl o

275 immunoassay might be implemented as a highly efficient tool for in situ monitoring of human stress le

276 Passive acoustic monitoring is an efficient tool to study temporal variations in the occur

277 epidemiological studies and sensitive, cost-efficient tools to detect amyloid are needed to better u

278 little is known about the design of CPPs for efficient transcellular transport.

279 here high and low NC valencies rendered less efficient transcytosis rates than an intermediate valenc

280 Efficient translational bypassing of a 50-nt non-coding

281 ing two intracellular compartments to enable efficient transport of a virus between these compartment

282 bout a 6.5 angstrom diameter, mediate highly efficient transport of diverse types of anions, rather t

283 onohydroxycorynomycolate (hTMCM) enables its efficient transport to the periplasm in Corynebacterium

284 ing EET-dependent anammox process for energy-efficient treatment of nitrogen.

285 Salvage liver transplantation is an efficient treatment of recurrences within criteria.

286 potential interventions that might result in efficient treatment of social-emotional disorders.

287 Anti-VEGF agents are efficient treatment to maintain visual acuity in residua

288 thiophene-functionalized derivative leads to efficient triplet pair separation, giving rise to an ove

289 reatly improved theranostic nanomedicine for efficient tumor suppression, and more importantly, inhib

290 f the architecture of GalNAc conjugation for efficient uptake by target liver cells and indicate that

291 KAS, a QALY maximization approach makes more efficient use of deceased donor kidneys but reduces acce

292 counteract its antiviral effects and promote efficient viral replication.IMPORTANCE Host cells mount

293 SpyCatcher003 enabled efficient VLP conjugation and extreme thermal resilience

294 The apparent diffusion co-efficient was determined for each lesion, and then the m

295 ch increases the imaging speed, providing an efficient way for high-resolution imaging of large exten

296 ATEMENT Learning from observing others is an efficient way to acquire knowledge.

297 as a basis for managing livestock in a more efficient way.

298 nd defined PTEN as a promising biomarker for efficient WEE1 cancer therapy.

299 Moreover, GRF4-GIF1 induced efficient wheat regeneration in the absence of exogenous

300 Efficient wound repair is critical to reestablish the mu