ライフサイエンスコーパス: eggshell

1 oogenesis (two respiratory appendages on the eggshell).

2 eralized matrixes of bone, dentin, and avian eggshell).

3 tratified arrangement resembling turtle soft eggshell.

4 cient to generate a DR-like structure on its eggshell.

5 ling the patterning and morphogenesis of the eggshell.

6 mbryonic membrane and the inner layer of the eggshell.

7 of the inner vitelline membrane layer of the eggshell.

8 nian fluid constrained within an ellipsoidal eggshell.

9 endages (DAs) of the Drosophila melanogaster eggshell.

10 space between the embryonic membrane and the eggshell.

11 tterns the operculum structure of the mature eggshell.

12 ith respect to the intrinsic polarity of the eggshell.

13 is required for functional properties of the eggshell.

14 d the subsequent formation of an impermeable eggshell.

15 verlying specific structural features of the eggshell.

16 s, which encode structural components of the eggshell.

17 of the dorsal respiratory appendages of the eggshell.

18 rning determinant that is a component of the eggshell.

19 elline membrane (VM), the inner layer of the eggshell.

20 extracellular space between the egg and the eggshell.

21 a gap between these ingressing cells and the eggshell.

22 e for synthesis and/or in the degradation of eggshell.

23 derivatives in the assembling and completed eggshell.

24 innermost layer of the C. elegans embryonic eggshell.

25 rane and the vitelline membrane layer of the eggshell.

26 cells that will create the operculum of the eggshell.

27 gene result in partial ventralization of the eggshell.

28 l-ventral polarity of the embryo but not the eggshell.

29 the stage 8 oocyte and ventralization of the eggshell.

30 al appendages in the correct position on the eggshell.

31 enance of the impermeable lipid layer of the eggshell.

32 ole in the formation and melanization of the eggshell.

33 species, and is absent from D. melanogaster eggshells.

34 urus eggshells with soft, non-biomineralized eggshells.

35 ow cavities of birds as a calcium source for eggshelling.

36 onsible for the patterning of the Drosophila eggshell, a complex structure derived from a layer of fo

37 ble to separate the plasma membrane from the eggshell, a defect analogous to that of incomplete vulva

38 a embryo, is stably anchored in the fruitfly eggshell; an as yet unidentified factor is required for

39 The embryo was found in an egg with thicker eggshell and a partly different geochemical signature th

40 ng of the origin and evolution of calcareous eggshell and amniotic eggs in general, is largely based

41 n the filarial nematode Onchocerca volvulus, eggshell and cuticle, suggests that some of the Ce-CPL-1

42 Accordingly, thin eggshell and DA phenotypes were identified for the calci

43 ing a novel probe, we detected chitin in the eggshell and discovered elaborate chitin localization pa

44 The eggshell and egg-laying defects of cuff mutants are supp

45 uding variable dorsal-ventral defects in the eggshell and embryo, anterior-posterior defects in the f

46 , establishing the dorsoventral asymmetry of eggshell and embryo.

47 maternal fet activity produces a dorsalized eggshell and embryo.

48 Mutations in rhi disrupt eggshell and embryonic patterning and arrest nurse cell

49 alysis identified 99 chorion proteins in the eggshell and micropyle localization of 1 early and 6 Hc

50 Eggshell and osteological evidence combined in this sing

51 epithelia, serosa and amnion, line the inner eggshell and the ventral germband, respectively.

52 occurred consistently in the absence of the eggshell and the vitelline envelope.

53 a former breeding colony and include intact eggshells and bones of embryos, juveniles, and adults of

54 non-avian saurischians that have associated eggshells and embryos are represented only by the saurop

55 It represents the first associated eggshells and embryos of megalosauroids, thus filling an

56 ulted in embryos that lacked chitin in their eggshells and failed to divide.

57 for twin peaks produce small eggs with thin eggshells and short dorsal respiratory appendages.

58 the major protein components of the chorion (eggshell) and are arranged in two clusters in the genome

59 and nitrogen (delta15N) in blood, feathers, eggshell, and bone have been used in seabird studies sin

60 usions, unstable cell divisions, a defective eggshell, and deposition of extracellular material.

61 caris suum, occurs inside a highly resistant eggshell, and the developing larva is bathed in perivite

62 s the same age as those with burnt Genyornis eggshell, and then continually to modern time.

63 s temporally correlated with the loss of the eggshell, and we used immunohistochemistry to report tha

64 ficient mosquitoes have nonmelanized fragile eggshells, and all embryos are nonviable.

65 duction in progeny, morphologically aberrant eggshells, and disintegrating egg chambers, indicating d

66 s by 4-5 fold, resulting in thin and fragile eggshells, and female sterility.

67 logical polymer, which can be extracted from eggshells, and has been used for adsorption of dyes or h

68 ophila melanogaster, each of the two tubular eggshell appendages is derived from a primordium compris

69 The roof of dorsal eggshell appendages is formed by the follicle cells that

70 ial for the formation of the two respiratory eggshell appendages, is established by a single gradient

71 prefigures the formation of two respiratory eggshell appendages.

72 tivity of the late enhancer and induction of eggshell appendages.

73 that prefigures the formation of respiratory eggshell appendages.

74 Drosophila egg gives rise to the respiratory eggshell appendages.

75 that form the upper part of the respiratory eggshell appendages.

76 ce of C22, one or more key components of the eggshell are inappropriately processed, leading to perme

77 While abundant structural components of the eggshell are known and are being characterized, less is

78 ty, gross morphological abnormalities in the eggshell are observed only in the absence of fc177.

79 Known dinosaur eggshells are characterized by an innermost membrane, an

80 essential features of the silkmoth chorion (eggshell) are still not fully understood.

81 -1 is also present near the periphery of the eggshell as well as in the cuticle of larval stages sugg

82 trol the availability of molecules active in eggshell assembly and by extension perhaps other follicl

83 These findings delineate the hierarchy of eggshell assembly and define key molecular mechanisms at

84 Proper eggshell assembly requires wild-type dec-1 gene function

85 The dec-1 gene, which is required for proper eggshell assembly, produces three proproteins that are c

86 rizing intermolecular disulfide bonds during eggshell assembly.

87 roproteins required for female fertility and eggshell assembly.

88 a framework for future molecular studies of eggshell assembly.

89 ts that are likely to play critical roles in eggshell assembly.

90 ves suggest that they play distinct roles in eggshell assembly.

91 hat each derivative plays a distinct role in eggshell assembly.

92 to the embryo, becomes incorporated into the eggshell at a position corresponding to the location of

93 fferent requirement in the patterning of the eggshell axis than in the patterning of the embryonic ax

94 hrough strontium isotope analyses of ostrich eggshell beads from highland Lesotho, and associated str

95 Podocarpus bark, worked suid tusks, ostrich eggshell beads, bone arrowheads, engraved bones, bored s

96 ments include marine shell beads and ostrich eggshell beads, directly dated to approximately 42,000 B

97 the Nudel protease might be involved in both eggshell biogenesis and embryonic patterning.

98 t the Nudel protease has an integral role in eggshell biogenesis.

99 varian follicle cells is essential for rapid eggshell biosynthesis.

100 vesicles accumulate in uterine fluid during eggshell calcification and that they contain high levels

101 11, 2.8%; 95% CI: 1.4%, 5.0%), nodules with eggshell calcifications (n = 9, 2.3%; 95% CI: 1.1%, 4.3%

102 ere we show that clumped isotope analysis of eggshells can be used to determine body temperatures of

103 These results showed that eggshell chitin provides both mechanical support and che

104 on developmental amplification of Drosophila eggshell (chorion) genes [1].

105 NA replication that control amplification of eggshell (chorion) genes during Drosophila oogenesis.

106 Drosophila amplifies eggshell (chorion) genes in the follicle cells of the ov

107 at origins that control amplification of the eggshell (chorion) protein genes.

108 and soft-shelled, fossil and extant diapsid eggshells clusters the originally organic but secondaril

109 l coloration (SSEC) hypothesis proposed that eggshell color is a sexually selected signal through whi

110 Recently, the sexually selected eggshell coloration (SSEC) hypothesis proposed that eggs

111 discoveries expand our understanding of how eggshell colour diversity is achieved.

112 Most avian eggshell colours can be produced by a mixture of these t

113 How eggshell colours help maintain thermal balance is a long

114 peting selective pressures further influence eggshell colours in warmer climates.

115 nts and biliverdin reproduces the respective eggshell colours.

116 The calcitic eggshell consists of one or more ultrastructural layers

117 The eggshell consists of proteins and proteoglycans that int

118 The Drosophila eggshell consists of three major proteinaceous layers: t

119 the oocyte proximal layer of the Drosophila eggshell, contains four major proteins (VMPs) that posse

120 s thermal degradation experiments of ostrich eggshell, coral skeleton, and limpet shell.

121 otor circuit, we found that reversals in the eggshell correlated with calcium transients in AVA inter

122 ell preserved remains of bone, feathers, and eggshell dating from hundreds to thousands of years B.P.

123 had no significant effect upon the lambdatop eggshell defect whereas smt3 and dock alleles significan

124 auses cytokinesis failure that is not due to eggshell defects or chromosome nondisjunction.

125 es are viable and exhibit a range of eye and eggshell defects.

126 CHS-1 is required for eggshell deposition, whereas MBK-2 is required for the d

127 e block to polyspermy, F-actin dynamics, and eggshell deposition.

128 equired in ovarian follicle cells for normal eggshell development.

129 al granule trafficking was disrupted and the eggshell did not form properly.

130 i.e., coating by dropping CR leachate on the eggshell; dipping the eggs into CR leachate; microinject

131 pendages, or respiratory filaments, of these eggshells display a remarkable interspecies variation in

132 However, tinamou (Tinamidae) eggshells display colours not easily rationalised by com

133 Drosophila eggshells display remarkable morphological diversity amo

134 ermline-to-soma signal, morphogenesis of the eggshell dorsal appendages.

135 sits from >100 ka to present; burnt Dromaius eggshell first appear in deposits the same age as those

136 as heated at 97 degrees C in the presence of eggshell for 60 min.

137 features is the absence of preserved eggs or eggshell for the first third of the known 315 million ye

138 l oxidase enzyme activities are critical for eggshell formation and production.

139 linked complexes during the early stages of eggshell formation that included other VMPs, namely sV17

140 y phenotype, thought to result from abnormal eggshell formation.

141 In Drosophila the multilayered eggshell forms during late oogenesis between the oocyte

142 00,000 y ago, the engraved ochre and ostrich eggshell fragments from the South African Blombos Cave a

143 and chemical characterization results of the eggshell fragments indicate very mild diagenesis.

144 ere we show that diagnostic burn patterns on eggshell fragments of the megafaunal bird Genyornis newt

145 lta13C and delta15N values of Adelie penguin eggshell from abandoned colonies located in three major

146 pes in fossil emu (Dromaius novaehollandiae) eggshell from Lake Eyre, South Australia, demonstrate th

147 f composition and ultrastructure, we compare eggshells from Protoceratops and Mussaurus with those fr

148 More than 700 dates onGenyornis eggshells from three different climate regions document

149 umen-like structure along the dorsal side of eggshells, from numerous Drosophila species.

150 During Drosophila oogenesis the chorion (eggshell) gene loci are amplified approximately 80-fold

151 Advanced mineralization of amniote eggshell (>=150 um in thickness) in general occurred not

152 In insects, eggshell hardening involves cross-linking of chorion pro

153 ityrosine-mediated protein cross-linking and eggshell hardening.

154 ails in spherical par-3 embryos in which the eggshell has been removed, but rotation occurs normally

155 rosaurid, a few sauropodomorph and tetanuran eggshells have been discovered; the paucity of the fossi

156 In this paper, food waste, namely eggshell (hydroxyapatite) utilization, was used to remov

157 Australia, were created by humans discarding eggshell in and around transient fires, presumably made

158 n porphyrin catabolites and are found in the eggshells in conjunction with biliverdin IXalpha.

159 protein sequence in ostrich (Struthionidae) eggshell, including from the palaeontological sites of L

160 elium also determines the final shape of the eggshell, including the dorsal respiratory appendages, w

161 an epithelium of follicle cells creates the eggshells, including the paired tubular dorsal appendage

162 ss spectrometry radiocarbon dates on ostrich eggshells indicates an age range of 23,576-22,887 y B.P.

163 Our findings suggest that the eggshell inhibits foreign body granuloma formation long

164 llow family members previously implicated in eggshell integrity, a heme peroxidase, and a small-molec

165 The compound, named C22, primarily impairs eggshell integrity, leading to osmotic sensitivity and e

166 ction, because mutations in yellow-g disrupt eggshell integrity.

167 The avian eggshell is a critical physical barrier, which permits e

168 The Drosophila eggshell is a highly specialized extracellular matrix th

169 The Drosophila eggshell is an elaborate structure that is derived from

170 not recruit macrophages, revealing that the eggshell is immunologically inert.

171 ed dispersal of F-actin is altered, a chitin eggshell is not formed, and no polar bodies are produced

172 he elephant bird egg is slightly larger, its eggshell is roughly five times thicker and shows a subst

173 abnormal eggshell proportions, and multiple eggshell layers best interpreted as a multi-layered egg

174 e of the structural units which comprise the eggshell layers, there is little knowledge of how indivi

175 tic tributaries), as well as formation of an eggshell-like inner membrane shielding the aortic intima

176 spectrometry-based analyses of fractionated eggshell matrices to validate six previously predicted e

177 major vesicular, mineralization-specific and eggshell matrix proteins in the uterus and in purified E

178 Such a large egg with a relatively thin eggshell may reflect derived constraints associated with

179 The eggshell membrane (ESM) is a naturally occurring biologi

180 iables on pepsin-soluble collagen (PSC) from eggshell membrane.

181 Carbonized sucrose-coated eggshell membranes (CSEMs) consisting of natural micropo

182 oocyte meiosis, formation of an impermeable eggshell, migration of the oocyte pronucleus, and the se

183 icular markers in the oviduct segments where eggshell mineralization occurs.

184 y edil3 is overexpressed in tissues in which eggshell mineralization takes place and that this overex

185 tabilized ACC in chicken uterine fluid where eggshell mineralization takes place.

186 We propose a comprehensive role for EVs in eggshell mineralization, in which annexins transfer calc

187 een the patterning of the follicle cells and eggshell morphogenesis.

188 are required for female fertility and proper eggshell morphogenesis.

189 Interestingly, we observed a range of eggshell morphologies from the new species, although the

190 that perturbations in WIT led to changes in eggshell morphologies in domains that are patterned by B

191 this can be used to account for more complex eggshell morphologies observed in related fly species.

192 , to interpret the phenotypic transitions in eggshell morphology and to predict the effects of new ge

193 grada is a species rich class, for which the eggshell morphology is one of the key morphological char

194 For one phenotype (eggshell morphology), we observed redundant regulation,

195 This new fossil provides insight into the eggshell morphology, early growth and nesting environmen

196 pod osteology with a specific and unique new eggshell morphology.

197 d-expressing cells and in this way influence eggshell morphology.

198 arated in time and have different effects on eggshell morphology.

199 nt to restore female fertility and wild-type eggshell morphology.

200 We describe four distinct eggshell morphotypes that have been collected from this

201 umpty dumpty (hd), corresponding to the thin-eggshell mutant fs(3)272-9 [3].

202 Unlike other thin eggshell mutants, mus308 displays normal origin firing b

203 Dromaius (emu) eggshell occur frequently in deposits from >100 ka to pr

204 their Sinemurian age indicate that the thin eggshell of basal sauropodomorphs represents a major evo

205 base of Dinosauria and that the much thicker eggshell of sauropods, theropods, and ornithischian dino

206 he Mesozoic era, explaining the bias towards eggshells of derived dinosaurs in the fossil record.

207 rphogenesis of the respiratory appendages on eggshells of Drosophila species provides a powerful expe

208 The eggshells of drosophilid species provide a powerful mode

209 apyrrolic bilirubin from the guacamole-green eggshells of Eudromia elegans, and red-orange tripyrroli

210 pyrrolic uroerythrin from the purplish-brown eggshells of Nothura maculosa.

211 led to greater pesticide accumulation in the eggshell or content than exposure through contact with t

212 hese latter embryos failed to produce normal eggshells or establish normal asymmetries prior to the f

213 mental approach led to the identification of eggshell organizing factor 1 (EOF1, AAEL012336), which p

214 f cis-regulatory regions of genes within the eggshell patterning network enables mechanistic analysis

215 Studies of the Drosophila eggshell patterning provide unique insights into the mul

216 mechanisms underlying the diversification of eggshell patterning, we analyzed BMP signaling in the FC

217 contrast to the previously proposed model of eggshell patterning, we show that the two-domain pattern

218 activation, which acts as a key receptor in eggshell patterning.

219 into a mechanism underlying the evolution of eggshell patterning.

220 -like molecule Gurken, which controls normal eggshell patterning.

221 change their provisioning behavior based on eggshell patterns they observe at the nest.

222 blishment, meiosis, and the integrity of the eggshell permeability barrier.

223 nant modifiers of the bullwinkle mooseantler eggshell phenotype and identified shark, which encodes a

224 itive 308 (mus308), exhibits a sporadic thin eggshell phenotype and reduced chorion gene expression.

225 A in spnB ovaries suppresses the ventralized eggshell phenotype by restoring Grk expression.

226 We used this easy-to-score eggshell phenotype in a germ-line mosaic screen in Droso

227 replication genes result in a distinct thin-eggshell phenotype owing to reduced amplification [2].

228 required for amplification results in a thin eggshell phenotype, allowing a genetic dissection of ori

229 ome for those that could enhance a weak Ras1 eggshell phenotype.

230 and mutant backgrounds exhibiting a range of eggshell phenotypes.

231 global spatial scale, we find evidence that eggshell pigmentation may have been shaped by thermoregu

232 and mass spectrometry, we identify two novel eggshell pigments: yellow-brown tetrapyrrolic bilirubin

233 p14, an eggshell precursor gene expressed only in sexually matur

234 ate microspheres containing a nonimmunogenic eggshell precursor protein of the parasite Fasciola hepa

235 d with most enzyme activity localized to the eggshell-producing cells contained within the vitellaria

236 Ground-sections reveal abnormal eggshell proportions, and multiple eggshell layers best

237 Calcified eggshells protect developing embryos against environment

238 chorion genes, which facilitate secretion of eggshell proteins [5].

239 proteins, most larger in mass than the major eggshell proteins and often showing preferential express

240 atrices to validate six previously predicted eggshell proteins and to identify eleven novel component

241 tly smaller by 48 h postinjection and lacked eggshell proteins.

242 ng two clusters of chorion genes that encode eggshell proteins.

243 regions, two of which contain genes encoding eggshell proteins.

244 e demand for the rapid synthesis of chorion (eggshell) proteins, Drosophila ovarian follicle cells am

245 coproteins that are consistently detected in eggshell proteomes.

246 The Drosophila eggshell provides an in vivo model system for extracellu

247 After eggshell removal by enzymatic digestion, embryo cells ar

248 ation of marine invertebrate shells or avian eggshells, respectively.

249 lial tubes whose lumens act as molds for the eggshell respiratory filaments, or dorsal appendages (DA

250 Mutant embryos are hyperactive within the eggshell, resulting in a high proportion reversed within

251 n-1 and -2, the dominant proteins within the eggshell, reveal that distinct domains bind to the miner

252 s, such as the appearance of the respiratory eggshell ridges, are caused by changes in the spatial di

253 rval eclosion and water uptake necessary for eggshell rupture and hatching.

254 y two pigments have been identified in avian eggshells: rusty-brown protoporphyrin IX and blue-green

255 eromone 7,11-heptacosadiene (7,11-HD) in the eggshell's wax layer deters egg cannibalism.

256 nd also that the confinement provided by the eggshell significantly affects the internal dynamics of

257 , egg quality parameters improved, including eggshell strength, eggshell thickness, albumen height an

258 I) by biosorption on egg traits (egg weight, eggshell strength, eggshell thickness, yolk colour, albu

259 erior columnar FC that produce the main body eggshell structure.

260 gshell types challenge efforts to homologize eggshell structures across all dinosaurs(8-18).

261 (SEM) analysis identified that exochorionic eggshell structures are strongly affected in EOF1-defici

262 The synthesis of dorsal eggshell structures in Drosophila melanogaster requires

263 Tubulogenesis of the Drosophila dorsal eggshell structures provides an excellent system for stu

264 ant eggs contain defects in several anterior eggshell structures that are produced by specific subset

265 mold for synthesizing the dorsal appendages--eggshell structures that facilitate respiration in the d

266 t construct epithelial tubes for specialized eggshell structures, has provided a tractable system to

267 uired for the formation of three-dimensional eggshell structures.

268 the follicle cells that give rise to dorsal eggshell structures.

269 80 clutches and their large eggs with thick eggshells substantiate that the Sanagasta sauropods were

270 of the morphological diversity of Drosophila eggshells, such as the prominent differences in the numb

271 quality and reduce the microbial load on the eggshell surface.

272 I proteins are localized to the sperm and to eggshells surrounding the developing embryos.

273 he formation of the permeability barrier for eggshell synthesis during embryogenesis.

274 ced by mutations in other loci that regulate eggshell synthesis suggest that the chorion production a

275 mber increases at several loci important for eggshell synthesis.

276 llicle cells of the ovary to allow for rapid eggshell synthesis.

277 ing in a high proportion reversed within the eggshell (the "retroactive" phenotype), and all show poo

278 The innermost layer of the Drosophila eggshell, the vitelline membrane, provides structural su

279 ls specifies two cell fates that pattern the eggshell: the anterior centripetal FC that produce the o

280 er treating hens with melatonin would affect eggshell thickness and improve skeletal performance, the

281 eters improved, including eggshell strength, eggshell thickness, albumen height and yolk colour.

282 n egg traits (egg weight, eggshell strength, eggshell thickness, yolk colour, albumen height) and per

283 ionship between SigmaPBDE concentrations and eggshell thickness.

284 stal condors have DDE levels associated with eggshell thinning in other avian species.

285 Pipe modifies components of the developing eggshell to produce a ventral cue embedded in the vitell

286 Then parasite antigens secreted through the eggshell trigger granulomas that facilitate egg extrusio

287 ilians and birds lay hard-shelled eggs, this eggshell type has been inferred for non-avian dinosaurs.

288 e fossil record and the lack of intermediate eggshell types challenge efforts to homologize eggshell

289 the presence of EDIL3 and MFGE8 proteins in eggshell, uterine fluid, and uterus.

290 Maximum adsorption capacity of eggshell was achieved as 923mgg(-1) for Pb(II).

291 py, we found that the Caenorhabditis elegans eggshell was composed of an outer vitelline layer, a mid

292 this process plays an essential role during eggshell waterproofing.

293 space between the embryonic membrane and the eggshell, which generate the ligand for the Toll recepto

294 The Drosophila eggshell, which has a pair of chorionic appendages (dors

295 In nematodes, this coat is the eggshell, which provides mechanical rigidity, prevents p

296 isibly collapsed and folded, presents a thin eggshell with a layered structure that lacks a prismatic

297 rvae swing their heads, scraping through the eggshell with their mouth hooks.

298 ized Protoceratops and the organic Mussaurus eggshells with soft, non-biomineralized eggshells.

299 In contrast, oviraptorid eggshells yield temperatures lower than most modern endo

300 Late Cretaceous titanosaurid eggshells yield temperatures similar to large modern end