ライフサイエンスコーパス: elderly patient

1 bstitute for transplant, particularly in the elderly patient.

2 tive outcome for allografts, particularly in elderly patients.

3 daily cardiovascular practice as we care for elderly patients.

4 at these benefits continue to be observed in elderly patients.

5 nce decreased with age but then increased in elderly patients.

6 outcomes than CAS outcomes noted in the more elderly patients.

7 with a disproportionately high incidence in elderly patients.

8 fficacy of ECT to treat severe depression in elderly patients.

9 the neurological examination particularly of elderly patients.

10 and large numbers of years of life saved in elderly patients.

11 t safety and efficacy of TAVR in select very elderly patients.

12 at repair, use of EVAR, and the treatment of elderly patients.

13 01) and a lower Nurick score (p<0.0001) than elderly patients.

14 ys and 10.4% (4.4% venous, 5.9% arterial) in elderly patients.

15 timing of aortic valve replacement, even in elderly patients.

16 ated in transplant-eligible patients than in elderly patients.

17 s those with mild initial stroke severity or elderly patients.

18 ity wounds can be challenging, especially in elderly patients.

19 ntraocular manifestations, and management of elderly patients.

20 ortunistic pathogen in immunocompromised and elderly patients.

21 asible and can also be proposed for selected elderly patients.

22 r benefit from recent oncology advances than elderly patients.

23 traumatic wounds that were slow to heal in 3 elderly patients.

24 503 (33.2%) were adults, and 848 (5.1%) were elderly patients.

25 ed data describe practice and outcomes among elderly patients.

26 alignancies, multiple myeloma mainly affects elderly patients.

27 each DOAC was similar or superior to VKA in elderly patients.

28 or those aged 80-84 years) than were younger elderly patients.

29 vents, and long-term outcome after CRT among elderly patients.

30 ently associated with all-cause mortality of elderly patients.

31 ction (NSTEMI), but the trials excluded very elderly patients.

32 morbidity and mortality risks, especially in elderly patients.

33 tic valve replacement and lung transplant in elderly patients.

34 Mortality (p < 0.0005) was higher in elderly patients.

35 nd treatments for end-stage liver disease in elderly patients.

36 itional reference range of 4 to 5 mU/L among elderly patients.

37 acute phase were compared between adult and elderly patients.

38 e significantly improved in highly compliant elderly patients.

39 course with significant excess mortality in elderly patients.

40 sease with a poor prognosis, particularly in elderly patients.

41 o EBV-associated B cell lymphomas such as in elderly patients.

42 not significantly different among adult and elderly patients.

43 apies for treating impaired wound healing in elderly patients.

44 Comorbidity is frequent, particularly in elderly patients.

45 e healing and increased rates of nonunion in elderly patients.

46 paroscopic approach on this diverse group of elderly patients.

47 ntation of bone marrow-derived stem cells in elderly patients.

48 lowing questions: Should RT be advocated for elderly patients?

49 the 6-year period and remained unchanged for elderly patients (0.8 cases per 1000 discharges in 2007

50 iction model to estimate the outcome of very elderly patients 12 months after being admitted to the I

51 This increase was more prominent in elderly patients (12%) but less so in inpatients (2.6%).

52 e cause-specific survival remained worse for elderly patients (3-year CSS, 60.8%; 95% CI, 59.6%-61.9%

53 ilator-associated pneumonia was higher among elderly patients: 35% in middle-aged patients versus 51%

54 verall mortality was significantly higher in elderly patients (5% vs 52%; p < 0.0001).

55 ; and 50-69 y, 26.3%), and then increased in elderly patients 70 years and older (31.9%).

56 17.6 [6.6]), organ support was higher in the elderly patients (77.0% vs 68.1%, p<0.0001), and median

57 Extraintestinal manifestations were lower in elderly patients (9.6% vs 19.2%, p = 0.061).

58 ee-for-service claims data was performed for elderly patients admitted for hemorrhagic stroke in 2008

59 hanges in primary noncardiac diagnoses among elderly patients admitted to a CICU during the past deca

60 Using 2003 to 2013 Medicare data, we grouped elderly patients admitted to CICUs into 2 categories bas

61 y, as with the wider population, outcomes in elderly patients admitted to ICU are improving over time

62 safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.

63 Elderly patients (age >/= 70 years) with limited-stage s

64 n the entire cohort and 6-month mortality in elderly patients aged 65 years or older matched to data

65 rge nationally representative cohort of 3418 elderly patients (aged >/= 70 years) with CKD undergoing

66 temozolomide alone or radiotherapy alone in elderly patients (aged >/=60 years) with GBM; articles w

67 The appropriate treatment approach for elderly patients (aged >65 years) with GBM remains uncle

68 Elderly patients also exhibited RyR2 hyperglycation and

69 Although the proportion of elderly patients among renal transplant recipients has i

70 LST to a nationally representative cohort of elderly patients Analysis of Surveillance, Epidemiology,

71 staphyloma might cause visual impairment in elderly patients and can be considered atypical forms of

72 l lymphoma, leg type (PCDLBCL-LT), occurs in elderly patients and has been considered as a lymphoma w

73 line in upfront chemoimmunotherapy for these elderly patients and highlight the need of prospective c

74 ng several lifestyle factors in non-demented elderly patients and moderately positive interim results

75 Extreme mortality after ECMO in elderly patients and patients requiring cardiopulmonary

76 oregionally confined head and neck cancer in elderly patients and propose a practical treatment algor

77 g in the establishment of bile stream in the elderly patients and the ones who are not good candidate

78 ot always benefit from treatment, especially elderly patients and those with baseline TSH levels belo

79 declining renal function was more common in elderly patients and those with cardiovascular comorbidi

80 Elderly patients and those with hyperlipidemia experienc

81 ) infection disproportionally affects frail, elderly patients and those with multiple chronic comorbi

82 nts can induce hepatotoxicity, especially in elderly patients and those with polypharmacy.

83 Cerebral amyloid angiopathy is common among elderly patients, and is associated with an increased ri

84 ith iatrogenic thyrotoxicosis, especially in elderly patients, and there is no evidence that it is be

85 ominantly hospitalized New York City cohort, elderly patients are at highest mortality risk.

86 Elderly patients are at particularly increased cardiovas

87 as recently received increased attention, as elderly patients are at substantially elevated risk for

88 Large prognostic studies evaluating elderly patients are currently lacking.

89 aortic valve replacement (TAVR) in the very elderly patients are limited, as they often represent on

90 accurate methods for risk stratification of elderly patients are necessary to decrease the occurrenc

91 ces in pharmacologic treatment of adults and elderly patients are not necessarily because of a milder

92 Colon resections in elderly patients are often done in emergent settings.

93 Elderly patients are the fastest-growing group in need o

94 While elderly patients are underrepresented in clinical trials

95 eg-patients with poor performance status and elderly patients-are not specifically addressed, because

96 motherapy regimens, but optimal treatment of elderly patients as well for as patients with limited or

97 Mortality rates were higher in elderly patients at ICU discharge (elderly, 26.5%; older

98 s recommended to assess the vulnerability of elderly patients, but its integration in cancer treatmen

99 st burn injury is significantly different in elderly patients compared with adult patients and to ide

100 al consideration as all other burn patients, elderly patients continue to have substantially poorer o

101 d analysis of 869 individual newly diagnosed elderly patient data from 3 prospective trials.

102 rologic outcome in successfully resuscitated elderly patients depends on cardiac arrest characteristi

103 reater risk of postoperative mortality among elderly patients despite less aggressive treatment.

104 One elderly patient died of neutropenic sepsis in the first

105 y surgical diagnoses were more prevalent for elderly patients (elderly, 39.8%; older, 25.1%; younger,

106 new-user cohorts of propensity score-matched elderly patients enrolled in Medicare who initiated dabi

107 though under-represented in clinical trials, elderly patients experience similar survival outcomes co

108 Although most elderly patients experience symptom resolution after dac

109 In this natural experiment involving 329,976 elderly patients, exposure to appendectomy surgery and a

110 Antipsychotic drugs are widely prescribed to elderly patients for the treatment of a variety of psych

111 a multicenter, open-label, phase III trial, elderly patients >/= 70 years old with a PS of 0 to 2 an

112 In elderly patients >=75 years of age, the 5-year survival

113 ren (</=18 years), adults (19-54 years), and elderly patients (>/=55 years).

114 icantly lower mortality rate was observed in elderly patients (>/=60 y old) with stage I disease.

115 An increasing number of elderly patients (>/=65 years) receive a donor kidney fr

116 the National Cancer Database was queried for elderly patients (>/=65 years) with newly diagnosed GBM

117 In a subgroup analysis, elderly patients (>=65 years old) treated with laparosco

118 Elderly patients had a greater number of decompressed le

119 Elderly patients had a higher cardiac arrest rate (2.2 v

120 Elderly patients had a worse preoperative health status

121 Elderly patients had greater imaging utilization, hospit

122 w-up period of 4.2 years (range, 0-9 years), elderly patients had less IBD-specific outpatient health

123 Within 4 hours of cardiac arrest, elderly patients had significantly lower mean heart rate

124 Predicting outcomes in elderly patients has been historically challenging and P

125 cytic leukaemia; however, its application in elderly patients has been restricted by substantial myel

126 The high mortality rate in critically ill elderly patients has led to questioning of the beneficia

127 Over the past two decades, elderly patients have been more commonly admitted to ICU

128 stoperative delirium occurs in 10% to 60% of elderly patients having major surgery and is associated

129 h pneumonia-specific ICU admission rates for elderly patients identify a group of hospitals that may

130 However, elderly patients (ie >/=65 years of age) are still more

131 Among critically ill elderly patients in France, a program to promote systema

132 Polypharmacy is a well known problem in elderly patients in general, but its prevalence and effe

133 Elderly patients in long-term treatment with vitamin K a

134 : The incidence of OPSCC is increasing among elderly patients in the United States, likely driven by

135 intensity suggest selection of less comorbid elderly patients, indicating possible rationing based on

136 Risk prediction in elderly patients is increasingly relevant due to longer

137 The incidence of colorectal cancer in elderly patients is likely to increase, but there is a l

138 ure, the leading cause of hospitalization of elderly patients, is correlated with myocardial fibrosis

139 sociated head and neck cancers decreased for elderly patients (larynx: APC, -1.54; 95% CI, -2.00 to -

140 Uniform vascular access guidelines for elderly patients may be inappropriate because of the com

141 ore were higher for nonelderly patients than elderly patients (Modified Early Warning Score area unde

142 rospinal fluid (CSF) from cognitively intact elderly patients (N = 28) with MDD and age- and gender-m

143 rnative to radical cystectomy, especially in elderly patients not well suited for surgery.

144 Therefore, in many elderly patients, observation is the best therapeutic op

145 For chronically critically ill elderly patients on mechanical ventilation, prognosis fo

146 What should be the criteria to accept elderly patients on the waiting list for RT?

147 reatment regimens are often not suitable for elderly patients or for patients in developing countries

148 indicate caution against the use of LCCBs in elderly patients or patients with advanced hypertension

149 grel versus a standard dose of ticagrelor in elderly patients or those with a low body weight present

150 esulted in improved survival and has allowed elderly patients or those with comorbidity to receive an

151 nificant cause of morbidity, particularly in elderly patients or those with immune deficiency or unde

152 s, but fewer preexisting comorbidities among elderly patients (p = 0.007), who received a shorter dur

153 Bottom Line: For fit elderly patients platinum-based combination is associate

154 form of the disease, often in vulnerable or elderly patient populations.

155 Restricted to mechanically ventilated elderly patients, rates ranged from 13.9 to 30.1/10,000

156 r systematic ICU admission in critically ill elderly patients reduces 6-month mortality compared with

157 tality rate comparable to that of waitlisted elderly patients remaining on dialysis.

158 Head and neck cancer in elderly patients represents a major health burden becaus

159 Off-Pump Coronary Artery Bypass Grafting in Elderly Patients) revealed no significant difference in

160 In elderly patients (RICOVER-60 study), HRPFS-male was 1.1

161 For selected elderly patients, RT was shown to be superior to dialysi

162 eatment decisions for potentially vulnerable elderly patients should take into account data obtained

163 However, after 4 years of follow-up, elderly patients showed worse survival and the cause of

164 There have not been elderly patient-specific trials of these therapies.

165 gth of stay and in operative mortality among elderly patients suggest areas where regionalization may

166 or cost per bed day are made, especially for elderly patients, the cost of EGS will rise dramatically

167 On subanalysis of adults and elderly patients, the prevalence of domestic violence in

168 ar disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems.

169 ased therapies are currently being tested on elderly patients, there are limited data on the function

170 However, the corresponding HRs (95% CIs) for elderly patients (those 75-85 years old) were only 0.88

171 Elderly patients, those with established cardiovascular

172 trajectories in burned adults versus burned elderly patients to gain novel insights and better under

173 s needed to understand the decision to admit elderly patients to the ICU.

174 y of radiographically occult hip fracture in elderly patients, to define the higher-risk subpopulatio

175 onges did not reduce the incidence of SSI in elderly patients treated with a hemiarthroplasty because

176 2 studies that reported overall survival in elderly patients treated with radiotherapy alone.

177 el 2 study that reported overall survival in elderly patients treated with temozolomide alone, and 4

178 anded use of ambulatory surgery for managing elderly patients undergoing elective surgery procedures.

179 s) longitudinally collected from a cohort of elderly patients undergoing major surgery, comparing sam

180 f care is associated with worse outcomes for elderly patients undergoing major surgery.

181 djusted 30-day episode Medicare payments for elderly patients undergoing one of six procedures for re

182 In a cohort of 453 475 elderly patients undergoing PCI, 39 850 developed AKI (8

183 patients with pediatric or adult-onset IBD, elderly patients used fewer biologics and immunomodulato

184 d that active hypertension treatment in very elderly patients was beneficial by reducing blood pressu

185 around the stomach fundoplication (SASF) in elderly patients was performed.

186 ed States to determine if aggressive care of elderly patients was warranted.

187 Elderly patients were defined as those 65 years or older

188 Eleven elderly patients were evaluated as controls (mean age, 7

189 Forty-seven depressed elderly patients were included in this analysis.

190 Staphylococcal isolates from elderly patients were more likely to be MR, as were S au

191 harmacokinetic parameters in non-elderly and elderly patients were similar.

192 arrest in nonelderly patients compared with elderly patients, which has important implications for h

193 g about the utility of life support for very elderly patients who are admitted to the ICU.

194 that CRT should be the preferred strategy in elderly patients who are expected to tolerate the toxici

195 , surgical hip fractures) remains unclear in elderly patients who are suspected to have such fracture

196 to standard of care secondary prophylaxis in elderly patients who have survived an AMI would reduce t

197 30% of elderly patients who require emergency general surgery (

198 responses in cases of ASB compared to UTI in elderly patients who were hospitalized upon injury.

199 Survival is further limited in elderly patients, who are often unable to tolerate multi

200 Nonvalvular atrial fibrillation is common in elderly patients, who face an elevated risk of stroke bu

201 ce-based perioperative care programs for the elderly patients will assume increased importance.

202 ounger patients, a substantial proportion of elderly patients will have long-term survival.

203 ages, the number of operations performed on elderly patients will likely increase.

204 tic options and more aggressive treatment of elderly patients, will have major impact on the future n

205 the key to improving quality of life for the elderly patient with cancer is an awareness of their spe

206 More than half of all elderly patients with a CICU stay across the United Stat

207 In a cohort of elderly patients with a high atherosclerotic burden, fam

208 Methods We used SEER-Medicare data for elderly patients with a new diagnosis of advanced-stage

209 Conclusion Elderly patients with acute hip pain and negative or equ

210 Purpose Elderly patients with acute myeloid leukemia (AML) have

211 rans retinoic acid (ATRA) in treatment-naive elderly patients with acute myeloid leukemia (AML).

212 Elderly patients with acute myocardial infarction underg

213 However, the outcomes in elderly patients with advanced CKD who receive permanent

214 In conclusion, most elderly patients with advanced CKD who received predialy

215 Even in elderly patients with advanced cSCC, cetuximab was effic

216 t-effectiveness associated with sorafenib in elderly patients with advanced HCC.

217 enib is associated with improved survival in elderly patients with advanced HCC; however, it is not c

218 Here, in elderly patients with advanced non-small-cell lung cance

219 In elderly patients with advanced NSCLC, treatment allocati

220 iweekly CHOP-14 With or Without Rituximab in Elderly Patients With Aggressive CD20+ B-Cell Lymphomas)

221 s were confirmed in the validation cohort of elderly patients with AML (HR 11.08 [3.23-38.06]).

222 trial of decitabine followed by selinexor in elderly patients with AML has been initiated.

223 androlone significantly improves survival in elderly patients with AML without increasing toxicity.

224 ies such as BI 836858 with azanucleosides in elderly patients with AML.

225 schemic stroke, and cognitive dysfunction in elderly patients with and without Alzheimer's Disease (A

226 g proteomics, we identified seven additional elderly patients with Apo-CII-rich amyloid deposits, all

227 This study examines elderly patients with appendicitis, a common condition t

228 ways mediating inflammation and pain in most elderly patients with ASB are not quantitatively differe

229 Additionally, elderly patients with asthma have highest rates of morbi

230 use and breast cancer-specific mortality for elderly patients with breast cancer with and without men

231 resence of CMV DNA in the blood of adult and elderly patients with bronchial asthma to establish pote

232 Elderly patients with BVI, caused by persistent amblyopi

233 oaches, GCE models improve stratification of elderly patients with cancer according to their risk of

234 as life expectancy increases, the number of elderly patients with cancer is increasing.

235 ay of permanent access placement in selected elderly patients with CKD.

236 black vs white disparities in survival among elderly patients with colorectal cancer (CRC) were becau

237 rge ulcers and fungal infections, as well as elderly patients with comorbid ophthalmic conditions, as

238 as frequently observed among immunocompetent elderly patients with comorbidities or severe concomitan

239 in this medically inoperable group of mostly elderly patients with comorbidities were comparable with

240 tensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure randomize

241 tensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure; n=431),

242 f AVR with a cumulative incidence of >40% in elderly patients with degenerative AS who underwent eith

243 ute effect of antipsychotics on mortality in elderly patients with dementia may be higher than previo

244 ne induction chemoimmunotherapy in untreated elderly patients with diffuse large B-cell lymphoma.

245 rituximab schedule are the best reported for elderly patients with DLBCL to date.

246 omide as maintenance therapy with placebo in elderly patients with DLBCL who achieved a complete resp

247 PR to R-CHOP significantly prolonged PFS in elderly patients with DLBCL.

248 To address this, we examined two elderly patients with duplication of PLP1 in whom the ov

249 h better outcomes than sublobar resection in elderly patients with early-stage NSCLC.

250 lied a retrospective cohort design on 29,095 elderly patients with end-stage renal disease who died b

251 Hypofractionated radiotherapy for elderly patients with fair to good performance status is

252 or biopsy, accepted treatment paradigms for elderly patients with GBM include combined-modality ther

253 ported survival data related to treatment of elderly patients with GBM using either temozolomide alon

254 n this analysis of multimodality therapy for elderly patients with GBM, OS was superior with CMT comp

255 emozolomide alone with radiotherapy alone in elderly patients with GBM.

256 temozolomide monotherapy in the treatment of elderly patients with GBM.

257 Unplanned hospitalizations among elderly patients with GI cancer are common.

258 rs for early unplanned hospitalization among elderly patients with GI cancer.

259 The optimal management for elderly patients with glioblastoma (GBM) is controversia

260 acious without impairing quality of life for elderly patients with good performance status.

261 In contrast, elderly patients with HFpEF had more comorbidities and d

262 For elderly patients with HL, BV plus DTIC may be a frontlin

263 tigating improved therapeutic strategies for elderly patients with HPV-positive OPSCC should be perfo

264 Elderly patients with increased risk for postoperative c

265 In elderly patients with limited-stage small-cell lung canc

266 For elderly patients with mantle cell lymphoma (MCL), there

267 ndamustine (R-B) as first-line treatment for elderly patients with MCL.

268 tate, the disease had its greatest impact on elderly patients with medical comorbidities.

269 Ticagrelor use among elderly patients with MI was associated with higher risk

270 Elderly patients with minimal comorbid conditions meetin

271 e MM and the GEM2010MAS65 clinical trial for elderly patients with MM who had minimal residual diseas

272 A prespecified subgroup analysis of elderly patients with myocardial infarction (>=75 years)

273 p analysis of the VALIDATE-SWEDEHEART trial, elderly patients with myocardial infarction had a highly

274 patients with mucinous pancreatic cysts, and elderly patients with new-onset diabetes.

275 Survival outcome for elderly patients with newly diagnosed diffuse large B-ce

276 ation of CMP was observed to be effective in elderly patients with newly diagnosed MM.

277 ation was associated with worse prognosis in elderly patients with non-small cell lung cancer (NSCLC)

278 estinal hemorrhage compared with warfarin in elderly patients with nonvalvular atrial fibrillation.

279 en the unique challenges related to treating elderly patients with OPSCC, their limited enrollment in

280 over time were observed for both younger and elderly patients with OPSCC.

281 ate the frequency of systemic drugs taken by elderly patients with or without periodontitis and the p

282 erated and gave long-term survival in 36% of elderly patients with Ph(+) ALL.

283 between a hospital's ICU admission rate for elderly patients with pneumonia and the quality of care

284 with the highest rates of ICU admission for elderly patients with pneumonia; such hospitals were les

285 rticularly challenging in higher-risk, often elderly patients with pre-existing CV disease.

286 esponses; and acceptable safety in primarily elderly patients with R/M cSCC, supporting its use in cl

287 t detect reduction in clinical events in our elderly patients with recent AMI who were treated with 1

288 ool of ECD kidneys and to rapidly transplant elderly patients with satisfactory results because of th

289 le in determining the surgical interventions elderly patients with serious illness receive.

290 y available because of the growing number of elderly patients with significant comorbidities or high

291 fficacy comparable to that of doxorubicin in elderly patients with STS and offers superior tolerabili

292 transfusion strategy in a high-risk group of elderly patients with underlying cardiovascular disease

293 In conclusion, in elderly patients with unprovoked VTE who have stopped AC

294 Up to 40% of elderly patients with untreated diffuse large B-cell lym

295 omide with R-CHOP21 is effective and safe in elderly patients with untreated DLBCL.

296 combination of lenalidomide and R-CHOP21 in elderly patients with untreated DLBCL.

297 Use of MPT-T or mPR-R in elderly patients with untreated MM demonstrates no stati

298 titatively different from those seen in most elderly patients with UTI and warrant larger clinical st

299 ture and to provide guidance on how to treat elderly patients within three broad stages: (1) metastat

300 nical implementation of CPC-based therapy in elderly patients would benefit tremendously from underst