ライフサイエンスコーパス: elongating

1 nts to protect them from depolymerizing, not elongating.

2 By elongating a single pillar axis we are able to significa

3 , the 150 dimer complex can be attributed to elongating a T=4 capsid along its 5-fold axis by adding

4 itates delivery of new actin subunits to the elongating actin filament.

5 in stereocilia widening by preventing newly elongating actin filaments from depolymerizing.

6 ver, FOR1 stimulates the assembly of rapidly elongating actin filaments from PRF1-bound actin.

7 (VASP) can catalyze actin polymerization by elongating actin filaments.

8 ating activity of the Arp2/3 complex and the elongating activity of Ena/VASP proteins for the formati

9 triole length by counteracting the centriole-elongating activity of several centriole duplication pro

10 ar differences in the characteristics of the elongating aggregates, depending on the specific identit

11 verlapping microtubules at the centre of the elongating anaphase spindle.

12 to high-macromolecular-content solutions by elongating and aligning with other cells, an effect that

13 tegy to comprehensively map the positions of elongating and arrested RNA polymerase II (RNAPII) at nu

14 go a limited number of cell divisions before elongating and differentiating.

15 matocytes and the acrosomal region of round, elongating and elongated spermatids.

16 ular in-plane direction, with the cells both elongating and intercalating along the converging axis.

17 s application in fully automated tracking of elongating and intersecting actin filaments, detection o

18 m is flexible and capable of patterning both elongating and nonelongating tissues, and hence converti

19 immunolocalized to sieve elements, while for elongating and recently elongated internodes, SUTs also

20 ay accumulate Suc from the stem apoplasms of elongating and recently elongated internodes, whereas Sb

21 that regulate actin dynamics by nucleating, elongating, and bundling linear actin filaments.

22 l pole by secondary mesenchyme cells and the elongating archenteron during gastrulation; Cadherin (G

23 Tyrosine Y(373) plays a crucial role by elongating , as fourth member, the electron transfer (ET

24 ignment and fusion of interstitial ZYP1 loci elongating at zygotene so synapsis at centromeres is a c

25 at is covalently attached (lipidated) to the elongating autophagosomal membrane.

26 ity" prior to tubulin incorporation into the elongating axoneme.

27 s converted into the mature RS at the tip of elongating axonemes.

28 rs on the growth cone at the leading edge of elongating axons play critical guidance roles by recogni

29 erate filament nucleation then remain on the elongating barbed end and modulate filament elongation.

30 cating that AtFH14 moves processively on the elongating barbed end.

31 ut is notably less effective at processively elongating barbed ends than most well studied formins.

32 ct and separate MCCA oil directly from chain-elongating bioreactor broth with just an abiotic electro

33 m bud position and low R:FR and decreased in elongating buds.

34 Lamprey is incapable of elongating C22 substrates.

35 rocess, whereas the switching probability to elongating cell type increases with increasing pressure.

36 pressures where bacterial cells switch to an elongating cell type.

37 is governed by time, not cell size, rapidly elongating cells do not divide more frequently than slow

38 These rapidly elongating cells require tip-focused endomembrane traffi

39 In asymmetrically elongating cells, dynein-dependent spindle anchoring at

40 ls do not divide more frequently than slowly elongating cells.

41 binding sites in the cell walls of expanding/elongating cells.

42 t is only detectable in recently divided and elongating cells.

43 lpha-helical polypeptides can be produced by elongating charge-containing amino-acid side chains to p

44 oral events of neural differentiation in the elongating chick body axis to provide the first analysis

45 rowth kinetics of the germinating embryo and elongating coleoptile, which consequently enhances anaer

46 and longer, essentially the same as a stable elongating complex.

47 ng uncharacterized structural changes in the elongating complex; and Mfd-dependent termination, the a

48 GreB binds to actively elongating complexes at nearly diffusion-limited rates b

49 incorporated complexes, and not in correctly elongating complexes.

50 ondary structure on D-loop reactions, and by elongating D-loops.

51 TCAs, adding de novo dendritic segments, and elongating dendritic length, while maintaining dendritic

52 cleavage of the nascent transcript from the elongating DNA-dependent RNA ploymerase II.

53 s are ribonucleotide reductase M1 (RRM1) and elongating DNA.

54 Using direct biophysical measurements of elongating Drosophila egg chambers, we document robust m

55 ) for the incorporation of a nucleotide into elongating dsDNA in solution (DeltaG(o)(incorporation)).

56 Furthermore, cells within elongating ducts oriented both their protrusions and the

57 patially enriched in cells near the front of elongating ducts, whereas phosphorylated AKT was ubiquit

58 cell migration speeds from rear to front of elongating ducts, with the front characterized by both h

59 rease in chromatid arm length by transiently elongating during anaphase/telophase.

60 s in collaboration with specific priming and elongating E2 enzymes.

61 rspective to describe a case where the chain-elongating E2 UBE2S feeds back and directly stimulates t

62 nd activates its specialized ubiquitin chain-elongating E2 UBE2S in ways that differ from current par

63 cells, PEAK3 overexpression does not have an elongating effect on cell shape but instead is associate

64 e conjugated structures which are capable of elongating effective conjugation, reducing the optical b

65 This includes ES at the Sertoli cell-elongating/elongated spermatid interface, which is known

66 n that anchors and maintains the polarity of elongating/elongated spermatids (step 8-19 spermatids) i

67 to the failure of spermiogenesis because no elongating/elongated spermatids were detected in any of

68 the rate and coherence of cell motion in the elongating embryo using mechanical information that is t

69 ursors, located towards the posterior of the elongating embryo.

70 In many elongating embryonic structures, tissue lengthening is d

71 y influencing the SMAD response in the TE of elongating embryos.

72 sive 3D cancer cell migration via both actin-elongating Ena/VASP proteins and the Scar/WAVE complex,

73 olymer configuration suggests that the chain-elongating enzyme (rubber transferase; EC 2.5.1.20) is a

74 rved that AUX1 in lateral root cap (LRC) and elongating epidermal cells greatly enhance auxin's shoot

75 , the lens fulcrum, where the apical tips of elongating epithelial cells constrict to form an anchor

76 e two major peptidoglycan synthases in live, elongating Escherichia coli cells and after perturbation

77 olymerization by nucleating new filaments or elongating existing ones.

78 copy number and transcript abundance in the elongating fiber cells of Upland cotton (Gossypium hirsu

79 formation about mechanical properties of the elongating fibrils.

80 apu once it is bound to the barbed end of an elongating filament.

81 nucleation and binding to the barbed end of elongating filaments by the C-terminal half of Capu (Cap

82 llows direct examination of both the fate of elongating filaments upon instantaneous suppression of A

83 Both mechanisms yield rapidly elongating filaments with mDia1 at their barbed ends and

84 can (PG) hydrolase (PGase), which allows the elongating flagellar rod to penetrate through the PG lay

85 ite droplets is well known in the context of elongating fluid filaments and jets, we show here that,

86 We find that elongating follicles undergo repeated rounds of circumfe

87 e consequences of re-replication at actively elongating forks.

88 rate the DSB marker gammaH2Av is enriched at elongating forks.

89 r removal or bypass, but does not inactivate elongating forks.

90 eurons to extend the regeneration-associated elongating form of axon growth but had no impact on axon

91 in, we report that IKKalpha travels with the elongating form of ribonucleic acid polymerase II togeth

92 In WT mES cells, the elongating form of RNA pol II accumulates near Vezf1 bin

93 gher chromatin assortativity of the actively elongating form of RNA polymerase 2 (RNAPII) compared wi

94 that there is no discernable decrease in the elongating form of RNA polymerase II in either mutant.

95 The elongating form of RNA polymerase II, which is phosphory

96 We identify a possible role for the elongating form of RNAPII in mediating interactions amon

97 onic stem cells (ESCs) knocked in for a slow elongating form of RNAPII We show that a reduced transcr

98 injury signal in regulation of the intrinsic elongating form of sensory axon regeneration.

99 There was greater abundance of the active/elongating form of the RNA polymerase-II enzyme (RNAPII-

100 uring latency but was converted to an active elongating form upon reactivation induced by Rad21 deple

101 ctive polymerase at CYC1 into a productively elongating form.

102 a clear distinction between the stalled and elongating forms of the polymerase.

103 nd H4K20me1 histone marks compared to slower elongating genes.

104 s occurs through examining the tips of young elongating Gossypium hirsutum (Gh) and G. barbadense (Gb

105 that varies most between rapidly and slowly elongating growth plates.

106 d axonal translation of GAP-43 mRNA supports elongating growth.

107 hem to contract and pull more cells into the elongating hindgut.

108 ht-sensing organ (cotyledons) and in rapidly elongating hypocotyls of Arabidopsis thaliana PIFs initi

109 ement of several candidate regulators in the elongating hypocotyls.

110 e photoreceptor layers across the fovea were elongating in albinism, albeit at a reduced rate, compar

111 eobox gene recruits polymerase II and begins elongating in all tissues and cell lines that we tested,

112 sulting in increased penetration stress when elongating in soils of greater strength.

113 to identify genes expressed in pollen tubes elongating in vitro; however, little is known of the tra

114 ve been reported in peripheral nerves and in elongating injured axons of sensory neurons in vitro, pr

115 esterol, we observed budding lipid membranes elongating into the cytosol and/or membrane segments mig

116 ved that both the phospho-Ser2 levels in the elongating isoform of Pol II and the loading of Spt5 and

117 -PTase structures leads to a model where the elongating isoprene chain extends beyond the enzyme's ac

118 ees toward the endo-fused cyclopropane bond, elongating it to r = 1.69 A.

119 Inversion of the M2 TMD, achieved by elongating its C-terminus, underscores the contribution

120 A non-elongating ketosynthase domain transfers the polyketide

121 dissection of this process reveals that non-elongating ketosynthase domain-mediated transacylation c

122 ancers, allowing the recruitment of the CDK9 elongating kinase.

123 ate mimetic bearing ACPs in complex with the elongating KSs from Escherichia coli, FabF and FabB, in

124 likely evolutionarily conserved features in elongating KSs.

125 f neuromast and ampullary organ formation by elongating lateral line placodes, and even of other zebr

126 d BAR-domain proteins drives the scission of elongating membrane tubules.

127 that could be critical for tethering of the elongating mitoribosome onto the inner-mitochondrial mem

128 ructures (3.7 to 4.4 angstrom resolution) of elongating mitoribosomes bound to tRNAs, nascent polypep

129 r stereotypical cell division orientation by elongating mitotic cells along the main tension axis.

130 The elongating mouse anteroposterior axis is supplied by pro

131 t embryos indicate that transient binding of elongating muscle to exploratory sites could be a genera

132 Indeed, a slowly elongating mutant of RNAPII was able to rescue this defe

133 t which the ribosome adds amino acids to the elongating nascent chain influences the efficiency of th

134 During biosynthesis on the ribosome, an elongating nascent polypeptide chain can begin to fold,

135 rcates: domains of cell proliferation in the elongating nephron; and tubule fusion where the new neph

136 osome has evolved an exit tunnel to host the elongating new peptide, protect it from proteolytic dige

137 rase act at each telomere when telomeres are elongating (nonequilibrium conditions).

138 that the vast majority of 80S monosomes are elongating, not initiating.

139 transfer from the supersaturated WL into the elongating NWs growing horizontally, dislocation- and ca

140 ing O-Man glycosylation and the major enzyme elongating O-Man glycans, the protein O-mannose beta-1,2

141 forks, it binds to only the matured (and not elongating) Okazaki fragments of stalled forks.

142 nterfaces sustained greater tension than non-elongating ones.

143 sults show that clathrin is not required for elongating or shaping the endocytic membrane invaginatio

144 itive versions of today's protein catalysts, elongating other such HP polymers as ribosomes would now

145 on ftrxn) that are initiating transcription, elongating, pausing, or awaiting termination.

146 troduction of D-amino acid residues into the elongating peptide.

147 Rod system establishes rod shape de novo by elongating PG at nonpolar regions.

148 characterized a pulling force exerted by the elongating pharynx (foregut) on the anterior epidermis d

149 m RNA/DNA hybrid structures (R-loops) behind elongating Pol II and are especially prevalent over G-ri

150 RSC-depleted cells exhibit low levels of elongating Pol II and high levels of terminating Pol II,

151 a model whereby kinetic competition between elongating Pol II and Sen1 helicase establishes the temp

152 lts suggest that kinetic competition between elongating pol II and the Xrn2 exonuclease is integral t

153 romatin-bound cohesin is necessary to retain elongating Pol II at centromeres.

154 We find that elongating Pol II complexes complete transcription after

155 the Pol II C-terminal domain and dismantles elongating Pol II from DNA in vitro.

156 Mechanistically, Gdown1 is associated with elongating Pol II on the highly expressed genes and its

157 modifying enzymes like Set2 that travel with elongating Pol II remain largely unknown beyond their in

158 )-associated RNA by XRN2 and dissociation of elongating Pol II.

159 initiation factor TFIIF from free pol II and elongating pol II.

160 and Hos2) in promoting Spt6 interaction with elongating Pol II.

161 art of PAF1 complex, and SPT6 from the newly-elongating pol II.

162 mmunication between synergid cells and a tip-elongating pollen tube (PT) for the successful delivery

163 del of apical membrane traffic at the tip of elongating pollen tubes.

164 transcripts specifically enriched in in vivo-elongating pollen tubes.

165 Recruitment of PER complexes to the elongating polymerase at Per and Cry termination sites i

166 Notably, the association of Set1C with the elongating polymerase was not perturbed by monomerizatio

167 nlarge, a result that is simply explained if elongating polymerases become immobilized in transcripti

168 ly/disassembly events ("actin hotspots") and elongating polymers along the axon shaft ("actin trails"

169 blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes

170 for linking ubiquitin (UB) to substrates and elongating polyUB chains, respectively.

171 changes associated with decreased levels of elongating pre-mRNA and less efficient splicing.

172 n (ACP) from fatty acid synthases sequesters elongating products within its hydrophobic core, but thi

173 simple DNA segregating machines that use an elongating protein filament between sister plasmids.

174 oprotein (VASP), a family of conserved actin-elongating proteins, is an important aspect of regulatio

175 tter access to its target when Pol is in the elongating rather than terminating mode.

176 d through stop codons in a regulated manner, elongating rather than terminating the nascent peptide.

177 and increasing fluidity toward its posterior elongating region.

178 We found that SMARCAL1 travels with elongating replication forks, and its absence leads to M

179 e translational block, demonstrating that an elongating ribosome can disrupt the interaction.

180 Although the elongating ribosome is an efficient helicase, certain mR

181 ecular aspects of viomycin inhibition of the elongating ribosome using pre-steady-state kinetics.

182 ial uS3 promote the helicase activity of the elongating ribosome, suggesting that uS3 contacts with m

183 equences within the CHOP uORF serve to stall elongating ribosomes and prevent ribosome reinitiation a

184 We also observe that elongating ribosomes are unable to complete translation

185 Our data suggest that slowly elongating ribosomes can lead to queuing/stacking of sca

186 that although ZAK generally associates with elongating ribosomes on polysomal mRNAs, it specifically

187 consecutive Pro codons pose a challenge for elongating ribosomes.

188 We propose that dynamic sampling of elongating RNA by multiple proteins overcomes heterogene

189 of the multistep transcription process, the elongating RNA polymerase (RNAP) is dislodged from the D

190 Slippage of elongating RNA polymerase (RNAP) on homopolymeric A/T tr

191 Elongating RNA polymerase and the associated nascent RNA

192 By precisely tracking the waves of elongating RNA polymerase II (Pol II) during gene activa

193 ermined the X-ray crystal structure of yeast elongating RNA polymerase II (Pol II) in complex with a

194 ent transcript invades the DNA duplex behind elongating RNA polymerase II (Pol II).

195 Given that the elongating RNA polymerase II (RNAPII) stalls at this wel

196 Transcript elongation factors associate with elongating RNA polymerase II (RNAPII) to control the eff

197 )-DNA cleavage complexes are known to arrest elongating RNA polymerase II (RNAPII), triggering a prot

198 Ccr4-Not associates with elongating RNA polymerase II (RNAPII), which raises the

199 for recruitment of RNA processing factors to elongating RNA polymerase II (RNAPII).

200 phorylated form of the CTD characteristic of elongating RNA polymerase II and contains a phospho-CTD-

201 ted nucleotides, and coincide spatially with elongating RNA polymerase II and splicing components.

202 eEF1A1 then associates with elongating RNA polymerase II and the 3'UTR of HSP70 mRNA

203 romoting chromatin reassembly in the wake of elongating RNA polymerase II and transcriptional elongat

204 n of the dimer with naked DNA in the wake of elongating RNA polymerase II at the coding sequence of t

205 histone deacetylase complex is recruited by elongating RNA polymerase II to remove histone acetylati

206 r, which is correlated to the association of elongating RNA polymerase II with active GAL genes.

207 CSB and UVSSA proteins, as well as actively elongating RNA polymerase II, are required for this proc

208 omplexes recruited by activator proteins and elongating RNA polymerase II.

209 By observing single H-NS filaments and elongating RNA polymerase molecules using atomic force m

210 ion factors from the NusG family bind to the elongating RNA polymerase to enable synthesis of long RN

211 g, which is determined by the ability of the elongating RNA polymerase to recognize the sequence of t

212 H activates gene expression by tethering the elongating RNA polymerase to the ribosome.

213 by multiple upstream events associated with elongating RNA polymerase.

214 ined action determines the level of actively elongating RNA polymerase.

215 ed by their distinctive patterns of actively elongating RNA polymerase.

216 hanisms of interaction between condensin and elongating RNA polymerases (RNAPs) and find that RNAPs a

217 either sensitive to frequent dislodgement by elongating RNA polymerases (RNAPs) from the target promo

218 argets DNA lesions that block progression of elongating RNA polymerases.

219 d NusA at the interface between a NusG-bound elongating RNAP and the ribosome and propose that it can

220 Our results reveal that DksA effects on elongating RNAP are very different from those of GreB, s

221 Elongating RNAP forms a transcriptional bubble in which

222 Recruitment of additional factors to elongating RNAP may be another conserved function of thi

223 identify a cohort of genes marked by PRC and elongating RNAPII (S5p(+)S7p(+)S2p(+)); they produce mRN

224 actor-binding phospho-epitopes on the CTD of elongating RNAPII and directly through binding to specif

225 s throughout the gene bodies that track with elongating RNAPII and the leading edge of RNA synthesis.

226 indicate that positive torsion generated by elongating RNAPII causes transient loss of histone-DNA c

227 show that, upon TGFbeta treatment, JMJD3 and elongating RNAPII colocalize extensively along the intra

228 urthermore, Ccr4-Not interacts directly with elongating RNAPII complexes and stimulates transcription

229 ancy on highly active genes mirrored that of elongating RNAPII extending through the bodies and 3' en

230 ive, transcription-related redistribution of elongating RNAPII within transcribed regions toward the

231 nd TFIIS copurified with each other and with elongating RNAPII, while P-TEFb was not among the intera

232 riptional coactivator that functions through elongating RNAPII.

233 a functional association between SNAPC1 and elongating RNAPII.

234 elevated steady state auxin concentration in elongating root cells is up-regulation of cell wall remo

235 elevated steady state auxin concentration in elongating root cells is upregulation of cell wall remod

236 red that the pectin network is reoriented in elongating root epidermal cells.

237 B1/2 accumulate in the tip-growing domain of elongating root hairs.

238 ted with gradients of cell length in rapidly elongating roots and dark-grown hypocotyls.

239 portantly, this amplification is asymmetric, elongating runs in favorable directions and abbreviating

240 rrelation between Vezf1 binding and peaks of elongating Ser2-P RNA polymerase (Pol) ll, reflecting Ve

241 manchette, a unique structure at the base of elongating spermatid that directs formation of the flage

242 gotes, with an absence of mature flagella on elongating spermatids and epididymal sperm.

243 g deformed acrosomal formation, degenerative elongating spermatids and irregular head morphology in p

244 ization was not changed in the few remaining elongating spermatids of Meig1-deficient mice.

245 localizes to the manchette in the remaining elongating spermatids of Pacrg-deficient mice, indicatin

246 In the elongating spermatids of wild-type mice, PACRG colocaliz

247 s predominantly expressed in round and early elongating spermatids, and Hipk4 knockout males are ster

248 m of wild-type mice, and in the manchette of elongating spermatids, but in the Meig1 or Pacrg-deficie

249 In elongating spermatids, CnnT forms speckles on the giant

250 f the cytoplasm is incomplete in Ube2j1(-/-) elongating spermatids, compromising the release of matur

251 that Brdt colocalizes with acetylated H4 in elongating spermatids.

252 s a wave of "zippering" that passes down the elongating spinal axis, uniting the neural fold tips in

253 al progenitors (NMps) contribute to both the elongating spinal cord and the adjacent paraxial mesoder

254 During anaphase, the elongating spindle physically segregates the sister chro

255 igid components of the outer membrane of the elongating stalk, concurrent with stalk synthesis.

256 We also show that the pointed-end has a non-elongating state that dominates the observed filament ki

257 e linked footprint lengths to initiating and elongating states of the ribosome on leadered transcript

258 jor role in the hydraulic systems of leaves, elongating stems, and roots.

259 substrate selectivity was identified for the elongating step than in preceding acylation.

260 flow (BLF) of Casson liquid over a linearly elongating surface considering radiation and Joule heati

261 lonal analysis correlate with shaping of the elongating tentacles.

262 ension (GBE), a convergent-extension process elongating the body axis.

263 Transcription activation is enhanced by elongating the crRNA.

264 an overstretching transition at about 65 pN, elongating the DNA to about 1.7-fold.

265 t this hypothesis, we examined the effect of elongating the extracellular region of the CD28 ligand,

266 The identity of the enzyme further elongating the glycan to generate the final trisaccharid

267 We found that elongating the helices at their extremities by adding mo

268 itching factor by repeatedly compressing and elongating the molecular junction.

269 cranial self-stimulation in rats showed that elongating the N-alkyl chain decreased abuse-related eff

270 end in sequential discontinuous pulses, each elongating the nucleoid by 5%-15%.

271 ly(A) tail will remain untranslated, whereas elongating the poly(A) tail permits protein production.

272 They occur in the leaflets, usually elongating them, and also in the submitral apparatus, wi

273 actin networks, with factors such as formins elongating these filaments into filopodia.

274 lastoderm"), and posterior fates arise in an elongating tissue (called the "germband").

275 me1 modifications showed that they appear in elongating to condensing spermatids and predominantly as

276 early and late endolysosomal markers to the elongating tPCs.

277 Using native elongating transcript analysis (NET-seq), we show that t

278 uclear fractions, including mammalian native elongating transcript sequencing (mNET-seq).

279 Here, by use of native elongating transcript sequencing (NET-seq) and a variant

280 and powerful approach for performing native elongating transcript sequencing (NET-seq) in human cell

281 Applying native elongating transcript sequencing (NET-seq) to yeast cell

282 a coli by a novel approach, combining native elongating transcript sequencing (NET-seq) with RNase fo

283 ls at single-nucleotide resolution by native elongating transcript sequencing (NET-seq).

284 Analysis of Pol I native elongating transcript sequencing data in Saccharomyces c

285 Using native elongating transcript sequencing followed by RNase diges

286 ence elements influence Pol I in vivo Native elongating transcript sequencing studies reveal that Pol

287 Consequently, we have developed native elongating transcript sequencing technology for mammalia

288 uence reads than ChIP-seq or NET-seq (native elongating transcript sequencing).

289 quantitative fluorescence assays and native elongating transcript sequencing.

290 developed a simple and robust method, native elongating transcript-cap analysis of gene expression (N

291 anscription and protein association with the elongating transcript.

292 Second, using 5' merodiploid native-elongating-transcript sequencing, 5' mNET-seq, we assess

293 gnals cause disassembly of the highly stable elongating transcription complex (EC) over windows of tw

294 In bacteria, disassembly of elongating transcription complexes (ECs) can occur at in

295 sm of interactions between SMC complexes and elongating transcription machinery relevant from bacteri

296 nsitions between the poised, initiating, and elongating transcriptional states.

297 etic switch through premature termination of elongating transcripts due to collisions between RNA pol

298 mation of the gaps, the force exerted by the elongating tubes to permit passage was determined using

299 Based on previous analyses of fast and slow elongating VASP proteins by in vitro total internal refl

300 the difficulty of collecting pollen that is elongating within the solid maternal gynoecium.