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1  to a broad range of rotaxanes, the strategy enables 1:1 interactions of crown ethers with various fu
2 ible with diverse drugs and biologics, could enable a broad range of non-cutaneous and cutaneous drug
3  of neighboring category-selective areas may enable a dynamic and flexible representation of complex
4 was detected; hence the study was stopped to enable a further dose saturation study in a porcine kidn
5                                           To enable a new generation of anti-viral vaccines, we desig
6 ptically addressing ground-state spins would enable a wide range of applications in quantum informati
7                                   The method enabled a detection limit of ~110 fg/mL biotinylated bov
8                          Synthetic chemistry enables a bottom-up approach to quantum information scie
9 understand how an accessory subunit (CoREST) enables a chromatin enzyme (LSD1) to function on a nucle
10 ctive and demonstrate that VB theory readily enables a clear-cut resolution of both of these contribu
11 obe IR images and the mechanical phase image enables a combined probing of mechanical material proper
12          While disorder in the histone tails enables a large variation of inter-nucleosome arrangemen
13 oduce an on-tissue ozonization protocol that enables a particular straightforward derivatization of u
14                      The uncovered mechanism enables a pathogen to express foreign virulence genes du
15  demonstrate that structural systems biology enables a proteome-wide, computational assessment of cha
16 cursor during electron-induced decomposition enables a reaction between NH(3) and the Cl ligands that
17 eference samples at predefined intervals and enables a single-step batch correction and quantificatio
18 (2) -TFEP@MOF electrolyte protected Zn anode enables a Zn||Ti cell to achieve a high average Coulombi
19  by RNA-seq and a user-friendly data portal, enabling a broad range of biomedical investigations.
20  kinetic features of these metabolites, thus enabling a detailed analysis of the various pathways inv
21                                  This method enables access to low molecular weight oligomers, and mo
22 s the induction-force-distance relationship, enabling accurate force calibration and force feedback.
23 ld (i.e. under conditions of SABRE in shield enables alignment transfer to heteronuclei, SABRE-SHEATH
24 ps of spikelets; their rate and distribution enabled an accurate estimation of the number of connecte
25        A qualitative approach was adopted to enable analysis of subjective employee experiences of ch
26 e describe a strategy performed in Brazil to enable and accelerate KT in children <=15 kg based on th
27 tiated mechanical responses and consistently enables and extends functional use.
28 rception is a fundamental cognitive function enabling animals to flexibly assign sounds into behavior
29     Our work marks an important step towards enabling application-specific analog computing platforms
30         We developed a purification strategy enabling assaying of individual C-subtypes and impuritie
31 f quartz in commercial, 100% silica samples, enabling assessment of conformity of unknown samples to
32 y of natural language processing potentially enables automated chart review for identifying patients
33 ete and sense a diffusible molecule, thereby enabling bacterial groups to coordinate their behavior i
34  of DAPLE that diverges from that in GIV and enables better binding to Galpha(s) and Galpha(q) Unlike
35 nt for reducing indoor energy consumption by enabling better thermal insulation, promoting effective
36 eview how access to these substrates has now enabled biochemical studies that deepen our understandin
37 m fluoride whispering gallery mode resonator enables both high passive stability and 1 kHz instantane
38 -MMP-laden endosomes to the plasma membrane, enabling both invadopodia outgrowth and MT1-MMP exocytos
39 n on drought stress, and can inform genomics-enabled breeding for climate-resilient cereals.
40 ) lossless multiple light scattering events, enabled by a highly porous (>99.99%) non-absorbing nanoa
41 tributed to different fragmentation pathways enabled by allylic versus vinylic carbons.
42                             This strategy is enabled by epitaxial Fe(0.52) Rh(0.48) thin films design
43 y during its interaction with the antigen is enabled by its binding to a metallic surface that serves
44                    This mechanistic insight, enabled by microsecond-timescale MD simulations, will al
45                     Similar chemistry may be enabled by nickel(II) hydrides that store the reducing e
46 and their applications are expanding rapidly enabled by scalable manufacturing.
47  electron transfer of oxidoreductase enzymes enabled by single walled carbon nanotubes and colloidal
48 s the importance of the adaptability that is enabled by statistical similarity among RHP chains and o
49 ases production of hyaluronic acid, which is enabled by the reprogramming of glucose metabolism.
50               Analogous photoredox catalysis enables C-H activation and H/D exchange in a number of a
51 llular (ultrastructural) architecture, which enables cardiac contraction.
52 This structure-dependent mechanism therefore enables cells to selectively regulate coding and noncodi
53                      Its modular design also enables characterization of non-tumor hemodynamics (e.g.
54 gic approach using structural elucidation to enable chemistry design/SAR development.
55 ring revealed that confined nickel(II) sites enabled chemoselective and reversible binding to acetyle
56 riction and multi-well ferrielectricity, and enable combining dielectric and 2D electronic materials.
57                         CARMEN-Cas13 further enables comprehensive subtyping of influenza A strains a
58 on the solution structure of the aptamer and enable computational modeling of the docked complex with
59     Orienting the OEEF off the reaction axis enables control over stereoselectivity, enantioselectivi
60 ssel becomes proportional to its size, which enables convenient intensity-based analysis of vessel di
61 ith ligand-directed acyl imidazole chemistry enables covalent labeling of AMPA-type glutamate recepto
62 SCI is required for stage progression, which enables crossover formation, suggesting that the establi
63 5/patient) identified from tumor sequencing, enabling ctDNA detection in 96% of patients at baseline.
64 ings establish a HMGB2-TOP1cc-cGAS axis that enables cytoplasmic chromatin recognition and response t
65  by extracting more information from data to enable data-driven multiplexing with high accuracy.
66                                              Enabling data reuse and knowledge discovery is increasin
67                               The new matrix enables DB localization of authentic standards belonging
68 ition of high-resolution enhancer boundaries enables deconvolution of complex regulatory loci into mo
69 electrolyte flow during charging, the device enables dense Li plating and avoids porosity and dendrit
70 ncing depth of 5 million merge-able reads to enable detection of specific target genes.
71  Thus, our FRET-based nanoparticle biosensor enables detection of nucleic acid targets using a smartp
72 ce increased the charge transfer resistance, enabling detection of coliforms.
73                     The mechanistic insights enabled development of an electrochemically driven photo
74 otubule into its constituent protofilaments, enabling deviations from helicity and other sources of h
75 s, unimorphs, bimorphs, and printed elements enables differentiated mechanical responses and consiste
76 egy based on evaporation-induced assembly to enable directional ion transport via forming vertically
77 otoxic CNS innate immune populations and may enable discovery of selective neuroprotective strategies
78 encoded small molecule libraries (DELs) have enabled discovery of novel inhibitors for many distinct
79 ity in human prostate cancer biopsy samples, enabling disease classification.
80                                Prime editing enables diverse genomic alterations to be written into t
81 ify an adaptive circuit-based mechanism that enables Drosophila to form sleep-dependent and sleep-ind
82 linical presentation, genomic classification enables earlier treatment for high-risk patients as well
83   These discoveries illuminate base editing, enable editing at previously intractable targets, and pr
84 zation of marginal structural mean models to enable effect decomposition.
85 N-chloroamines to give aminium radicals that enable efficient alkene aminochlorination.
86 connecting two intracellular compartments to enable efficient transport of a virus between these comp
87                                SpyCatcher003 enabled efficient VLP conjugation and extreme thermal re
88 - and trans-eQTL of the target gene but also enables efficient computation by using summary statistic
89            We hypothesize that this approach enables embedded feature extraction and, integrated with
90 face-associated virulence factor InlB, which enables entry into certain host cells.
91 as well as human and murine skin epithelium, enabling epicutaneous vaccine delivery.
92 roach to quantifying reactivation risks will enable evaluations of the potential impacts of TB contro
93 age provides a suite of plotting methods and enables expedient, flexible and interactive visualizatio
94 ntal investigations into these processes and enables experiments with lower, relevant particle concen
95  active site via subtle changes in dynamics, enabling exquisite fine-tuning of delivery of these esse
96 Here, we devised novel analytical procedures enabling extensive and systematic investigation of the a
97 port of peptides through the PAN layer, thus enabling extraction of high amounts of peptides by the n
98 nto energy plants on Earth and possibly even enable extraterrestrial habitats.
99  kinetics and exquisite selectivity, thereby enabling facile modification of NCys-bearing proteins in
100 ld and can be computed efficiently enough to enable false discovery rate estimation via permutation.
101 ical systems, cooperativity between proteins enables fast actions, supra-linear responses, and long-l
102                                This paradigm enables further assessment of the interplay between unce
103 his quantitative and automated approach will enable future cohort studies to understand the microvasc
104 variants, aggregated into a polygenic score, enable genomic risk stratification, and to test whether
105 esults on a map, which we refer to as an "AI-enabled glaucoma dashboard." We used density-based clust
106                                         This enabled greater capacity for urgent and emergency cases,
107 p-intensity levels are also decoded from M1, enabling grip reanimation regulated by touch signaling.
108 cal in supporting health care workers and in enabling health care organizations to succeed and thrive
109 ne acceptors (NFAs) with crystalline domains enable high-performance bulk heterojunction (BHJ) solar
110 ors based on green fluorescent protein (GFP) enable high-resolution imaging of dopamine dynamics in b
111 e dual-comb photoacoustic spectrometer could enable high-speed spectrally resolved photoacoustic imag
112 nt of a droplet microfluidic platform, which enables high-throughput reaction discovery in flow to ge
113 oscopy, tomography, and other modalities are enabling high-resolution reconstructions of cellular and
114                       It can be augmented to enable higher data volumes and random access to the data
115 ge and instability of the drug in plasma and enabled higher drug accumulation in tumors compared to i
116                  Our microfluidic technology enabled highly reproducible production of multicomponent
117 ses from the fact that the secretion pathway enables ICG-PEG45 to be effectively effluxed out of norm
118  nuclear erythroid 2-related factor 2 (Nrf2) enables idebenone to bypass Complex I in cells with poor
119  to facilitate tumor antigen presentation by enabling immunogenic photodynamic therapy (PDT) and prom
120 ppropriate timing of face-to-face visits and enable improved application of treat-to-target strategie
121               Results from the pilot studies enabled improvements after each pilot test.
122 te TCs on a sub-ms timescale is essential to enable incorporation of the rare cognate amino acids int
123     Advances in cryo-electron microscopy are enabling increasingly elaborate sub-complexes to be reso
124                                  This device enabled independent access to the apical and basolateral
125 wborn screening to prevent ketoacidosis, and enables individualized risk estimates for better prevent
126                          The same controller enabled individuals with chronic stroke to remain standi
127  when indications for PMRT are borderline to enable informed decision-making regarding oncological an
128 lexed from ongoing efferent motor intention, enabling intracortically controlled closed-loop sensory
129 tive depletion of antibody-tagged leukocytes enables isolation of potentially viable CTCs without bia
130 itoylates phosphorylated STAT3 (p-STAT3) and enables it to translocate to the nucleus.
131  trehalose monohydroxycorynomycolate (hTMCM) enables its efficient transport to the periplasm in Cory
132 ccuracy of CT-FFR in this cohort potentially enables its use in clinical practice and provides the fo
133          TCR transfer to T cells of patients enabled killing of autologous and nonautologous melanoma
134 brain fluke) and recipients (abdomen flukes) enables kin selection of the parasite's host-manipulatin
135              The Li(3) N-LiF/Li(3) PS(4) SSE enables LiCoO(2) cathodes to achieve 101.6 mAh g(-1) for
136 ney Registry (NKR) Advanced Donation Program enables living donors the opportunity to donate altruist
137 in ferroelectric materials could potentially enable low-power perovskite ferroelectric tetragonality
138 approximately twofold, reduces toxicity, and enables lyophilized storage without loss of activity.
139 nking and immunoprecipitation (CLIP) methods enable mapping RBP targets transcriptome-wide, but metho
140               Genome-scale technologies have enabled mapping of the complex molecular networks that g
141 to constitute a problem-solving toolbox that enables mass spectrometry as a valuable tool for HOS elu
142 cent advances in mass spectrometry (MS) have enabled meaningful glycoproteomic undertakings, many tec
143 ent of both the response reproducibility, by enabling measurement in triplicate, and of the device se
144 on and highlight the use of model systems to enable mechanistic understanding of RAD51 cellular roles
145 role of driver genes in diverse contexts and enables mechanistic and translational studies.
146 Illumina platform should be size-selected to enable merging of paired end reads and should be sequenc
147 R instrument and finally piloted on an ISFET enabled microchip.
148           Active non-muscle myosin II (NMII) enables migratory cell polarization and controls dynamic
149 t ME materials are an excellent candidate to enable miniature bioelectronics for clinical and researc
150  tool to handle kinematic constraints, which enable modeling of kinematic loops (e.g., cycling models
151 e anticipate that this may be generalized to enable molecular strategies to complement heterogeneous
152 , especially effects of condition type, will enable more effective personalisation of care.
153 ates in the solvation sheath of lithium ions enabling more bis(trifluoromethanesulfonyl)imide anion (
154 e scales, larger actions, and blind testing, enabling more of biology's stories to be told in the lan
155                         This interaction may enable mRNA circularization, an apparently critical elem
156 ics, and integrative analysis of these data, enable new, systems-level insights into disease pathogen
157 to profoundly transform synthetic biology by enabling new approaches to the model-driven design of sy
158  design of new DEL synthesis technologies to enable next-generation drug discovery.
159 nces in scanning probe microscopy on surface enable not only direct observation of molecular structur
160 ental understanding of ionization that could enable novel membrane design.
161 ny cases, these peptide-based catalysts have enabled novel multifunctional substrate activation modes
162 modified exclusively at the N-terminus would enable O-glycoproteomic methods to rely solely on collis
163 n between LMA and electrolyte, approaches to enable operation of LMA in practical conditions, etc.
164  insensitive to magnetic field fluctuations, enabling optical linewidths of less than one megahertz a
165 epitaxy of colloidal polyhedral nanocrystals enables ordered grain growth and can thereby produce mat
166                              This study will enable other researchers in understanding the B. microti
167              Digital health technology could enable patient-reported outcomes to inform appropriate t
168 trates the use of ML as a viable strategy to enable personalized risk quantification for medical appl
169                             They efficiently enable PHD2 crystallization in different forms, both wit
170 demand for a general catalytic solution that enables precise control of the C=C bond migration positi
171                               This signature enables precise mapping of core fragility regions in kno
172                      These technologies have enabled previously inaccessible chemical transformations
173 ify individuals at high risk of COVID-19 and enable prioritization of PCR testing and containment eff
174                                       Butler enabled processing of a 725-terabyte cancer genome datas
175     Three-dimensional (3D) hydrogel printing enables production of volumetric architectures containin
176 ommercially applicable, so there are few CNM-enabled products on the market today.
177                    The feedback loop further enables prolonged production of BisDC, which ensures exp
178 ng for early POEMS diagnosis and potentially enabling prompt disease-directed therapy.
179              Ribosome occupancy measurements enable protein abundance estimation and infer mechanisms
180 otein Data Bank is now sufficiently large to enable proteins to be designed by using only examples of
181 ted ion chromatograms of isomeric glycoforms enabled quantitative assignment of Gd sites.
182 rizability can be mathematically correlated, enabling quantitative analysis.
183 is currently hampered by the lack of systems enabling quantitative and dynamic phenotypic characteriz
184 ate high-fidelity operation that effectively enables quantum communication at a rate that surpasses t
185 ds and redox-active ligands work together to enable rapid electrochemical CO(2) reduction at moderate
186 ein expression from promoter sequences would enable rapid generation of useful promoters and facilita
187 e design and evaluation of immunogenicity to enable rapid translation to the clinic.
188 tic CRL architecture that is both robust, to enable rapid ubiquitylation of the substrate, and fragil
189 while, the ultrasmall size of Cu(5.4)O USNPs enables rapid renal clearance of the nanomaterial, guara
190 mmunodiagnostic tests play a crucial role in enabling rapid and correct diagnosis of diseases in preh
191 or the repurposing of existing approaches to enable rapidly scalable epidemiologic data collection an
192 in a fast, affordable and reliable way, thus enabling real-time guidance for the government in provid
193  Additional phenotyping and in vitro studies enabled reclassification of a KCNQ1 variant from variant
194 experiences relatively higher cooperation by enabling recognition of marginal gains of cooperation in
195 K cells were inoculated with tissue lysates, enabling recovery of one IAV isolate confirmed by immuno
196           We suggest that certain mechanisms enabling regeneration may be co-opted by cancer to promo
197 ns of people across the globe, mobile phones enable relatively cheap and effective communication, as
198      Alkoxy radicals have long been known to enable remote C-H functionalization via 1,5-hydrogen ato
199 connected chambers allowed for perfusion and enabled replication of pressure/volume relationships fun
200 ombined in a 21T MALDI FT-ICR MSI experiment enable researchers to visualize molecular structures in
201 his data as a publicly accessible track hub, enabling researchers to explore this data set easily in
202 duces a heritable gene expression state that enables resistance to stress.
203 enes, optimal screen design can nevertheless enable robust screen performance.
204                     Modern recording methods enable sampling of thousands of neurons during the perfo
205             SPINE is the first technology to enable saturated domain insertion profiling.
206 mote growth in the field of cell biology and enable scientists to assess and assume their role in cre
207 he free and open-source OPERA application to enable screening of new chemicals with a defined applica
208       The low uncertainty of our method will enable searches for further soft-X-ray clock transitions
209                     Our screen for admixture-enabled selection relies on the identification of loci t
210 sponsiveness of IECs to type III IFN in vivo enables selective ISG expression during infection that c
211                  We present an approach that enables sensitive OA detection in presymptomatic individ
212 ccumulating knowledge from these studies has enabled several important recent breakthroughs.
213 es in CO(2) electrolysis are still needed to enable short-term and seasonal energy storage in the for
214                                  Low-dose CT enabled significant radiation dose reduction.
215                          All four procedures enable significantly improved sample throughput compared
216 onducting circuits into artificial atoms(2), enabling some of the best-controlled qubits today(3,4).
217                             This methodology enables spatial regulation of protein synthesis, and dec
218 nisms and constraints with which convergence enables stereotypy in sensory responses despite random c
219 olog of Polkappa, to induce mutagenesis that enables stress tolerance or escape.
220                                   NINJA will enable studies of how T cells respond to defined neoanti
221 on of chromatin condensation and cell death, enabling studies of viral plaque formation with single-c
222                                           To enable such temporal analysis from multimodal single-cel
223 anding the mechanisms of these processes may enable synthetic improvements and development of new rea
224  (ICIs) have transformed cancer treatment by enabling T cell reactivation; however, response biomarke
225               Finally, future directions and enabling technological advances for the field are discus
226 e flow chemistry has begun its rise as a new enabling technology to add to the ever increasing arsena
227 he unfurling of the second lectin ring which enables tetramer formation.
228 pate that the outcomes of this research will enable the broader use of gHDX in MS-based workflows for
229 g spatially distinct geochemical niches that enable the co-existence of multiple taxa that occupy the
230  GB segregation as an alloy design tool, and enable the design of microstructures that maximize the u
231                                    The AuNPs enable the detection of dimethyl sulfide and histamine a
232 eir extraordinary efficiency and selectivity enable the development of flawless structures, such as d
233 omal cells (EpiSC) by specific ligands might enable the direct imaging of EpiSCs after MI to better u
234 w that eCLIP peak co-occurrences across RBPs enable the discovery of novel co-interacting RBPs.
235 eserves connected by corridors are needed to enable the dispersal of flora and fauna.
236                          This technique will enable the exploration of biotin trafficking in humans a
237 ssing pathway enzyme, protein engineering to enable the functional expression of an acyltransferase v
238 vity and specificity of procalcitonin levels enable the practitioner to distinguish bacterial pneumon
239            This semiquantitative method will enable the procurement of exposure concentrations of air
240  understanding and demonstrated capabilities enable the rational design and holistic engineering of n
241                               This study may enable the realization of devices based on carbon nanoma
242                                      NMP can enable the reduction or avoidance of cold ischemia and a
243 ocess of condensate formation is proposed to enable the robust and precise changes in gene-regulatory
244  holes stabilized by surface adsorbed iodide enable the site-selective oxidative etching of Au(0), wh
245 ks for proteomics and data analysis and will enable the study of RBP dynamics under different physiol
246 uitylation of the substrate, and fragile, to enable the subsequent functions of cullin-RING proteins.
247 mplished via a set of automated scripts that enable the user to go from a set of raw data, such as fa
248 ir organization and their heterogeneity, and enabled the cellular architecture of breast cancer tissu
249 tive affinity purification-mass spectrometry enabled the delineation of the CD22 interactome in the B
250 el data-driven functional analytic tools has enabled the derivation of individualized multilevel dyna
251                                     CoxFluor enabled the detection of oxygen-dependent changes in COX
252 ncluding convolutional neural networks, have enabled the development of AF screening pathways using t
253 very of an HCV-like rodent hepacivirus (RHV) enabled the development of such a model in rats.
254 nd G protein-coupled receptors, has directly enabled the discovery of most drugs developed to modulat
255 nd recent improvements in DNA synthesis have enabled the manipulation of megabase genomes.
256 cussing both the synthetic methods that have enabled the preparation of these materials and the manif
257 leave after glycosylated Asn residues, which enabled the robust identification and orthogonal validat
258   Single-cell RNA sequencing (scRNA-seq) has enabled the simultaneous transcriptomic profiling of ind
259 omosome 12aF1 and human chromosome 14q32 has enabled the use of mouse models to elucidate imprinting
260                                      It also enables the acquisition of local X-ray absorption spectr
261  from aversive and appetitive systems, which enables the computation of integrated predictions that m
262 he accuracy of chemical structure prediction enables the development of machine-learning methods to p
263 g a state of transcriptional plasticity that enables the emergence of antiandrogen resistance through
264 al nickel/photoredox catalytic protocol that enables the first cross-electrophile coupling of unactiv
265                           This new precursor enables the fluorination and chlorination of remote C-H
266                   Our data suggest that CTCF enables the formation of chromatin loops by protecting c
267 SEPT9-dependent F-actin cross-linking, which enables the generation of F-actin bundles required for t
268                        Additionally, seagull enables the incorporation of weights for each penalized
269       The dual-parametric QTR-FRET technique enables the linking of guanine nucleotide exchange facto
270 he unique and versatile reactivity of nickel enables the oligomerization of ethylene, propylene, and
271 ent in the 'Dd2' isoform of PfCRT (PfCRTDd2) enables the protein to transport CQ away from its site o
272 a high-throughput microfluidic platform that enables the quantitative, single-cell precision analysis
273 ile and light activation of the nucleophile, enables the stereoselective installation of benzyl group
274 ure that enhances the templated reaction and enables the uncaging of a substrate.
275 ubstantially reduce measurement time thereby enabling the acquisition of reasonably large training da
276 on of an integrated multimodal imaging setup enabling the assessment of multiple, complementary param
277 ries of a dynamical matrix (or Hamiltonian), enabling the design of metamaterials with emergent prope
278  silicon by means of helium-ion irradiation, enabling the formation of a completely amorphous region
279 of strains from metagenomic sequencing data, enabling the identification of genes that predict bacter
280  sensitivity comparable to in vitro methods, enabling the measurement of energy landscapes in vivo.
281 ng antibodies against the short L1 appeared, enabling the virus to successfully establish an infectio
282 s, can encode quorum-sensing components that enable them to integrate host cell density information i
283 ire mutations in genes including DNMT3A that enable them to outcompete other HSCs and increase leukem
284 aviviruses in LC3+ secretory organelles that enables them to evade circulating antibodies and might a
285 neurons of the distal gastrointestinal tract enables these neurons to respond to the luminal environm
286        Here, R1441C and G2019S knock-in mice enabled thorough evaluation of dendritic spines and syna
287 cell technologies such as mass cytometry are enabling time series experiments to monitor the temporal
288 lication can improve vaccine availability by enabling transportation without refrigeration.
289 ting networks, and their abundant interfaces enable ultrafast charger diffusion across the entire ele
290 strated that synchrotron-based X-ray imaging enabled uncovering finer details of the variation of par
291          However, the neural mechanisms that enable us to respond to target stimuli while ignoring di
292  into human 3D skin constructs (HSCs), which enabled us to closely monitor and quantitate T cell resp
293 viral genomes from available patient samples enabled us to estimate that SARS-CoV-2 was introduced to
294  possible by leveraging IM separation, which enabled us to separate and analyze CID and ECD fragmenta
295 led within the Bass diffusion framework that enables us to compare the differential equation version
296 ramework is established based on Tempel that enables us to predict the mutations at any specific resi
297 model at the time the vaccine is introduced, enables us to predict whether the strain increases or de
298 including enantiomerically pure amino acids, enabling us to explore structural diversity.
299 n to phenotype tools, genetic analysis tools enable users to integrate and interpret genome-phenome r
300 ding and stimulation (Mo-DBRS) platform that enables wireless and programmable intracranial electroen

 
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