ライフサイエンスコーパス: endeavor

1 merging technologies helping to advance this endeavor.

2 cell remains an important bottleneck in this endeavor.

3 atural life remains a remarkably challenging endeavor.

4 l task, becoming the essence of our research endeavor.

5 atment of malaria and cancer is an important endeavor.

6 biosimilar LMWH has become an active global endeavor.

7 rve as the critical foundation of a research endeavor.

8 ecules, or cancer cells remains a formidable endeavor.

9 judgment, a costly and generally ineffective endeavor.

10 ac surgical patient is a complex and dynamic endeavor.

11 1,3-allylic-type strain) is central to this endeavor.

12 ctivate HER3 function has been a challenging endeavor.

13 ive synthesis of such structures is a useful endeavor.

14 the phase III randomized, multicenter trial ENDEAVOR.

15 o their asymmetric synthesis is an important endeavor.

16 trumentation and approaches facilitates this endeavor.

17 stainable solvents is therefore an important endeavor.

18 in diagnostic procedures to facilitate this endeavor.

19 low frequency in human cancers is an ongoing endeavor.

20 ration of novelty is central to any creative endeavor.

21 model, making correction a relatively simple endeavor.

22 or react is often the missing piece in this endeavor.

23 btaining their monomers has proved a complex endeavor.

24 We undertook such an endeavor.

25 copic objects is an exciting and challenging endeavor.

26 colipids in lipid membranes is a challenging endeavor.

27 es and personnel available to devote to this endeavor.

28 e ACR should continue this vital educational endeavor.

29 e sparing HSC is an attractive but difficult endeavor.

30 esonance imaging have taken the lead in this endeavor.

31 ences, despite considerable interest in this endeavor.

32 ther countries and regions embarking on this endeavor.

33 ic basis has proven to be a very challenging endeavor.

34 tinct, known entities is an inherently risky endeavor.

35 whole-cell biocatalysts is a low-throughput endeavor.

36 grand challenges underpinning this research endeavor.

37 g with chemical specificity is a challenging endeavor.

38 s a very complex and computationally intense endeavor.

39 talyst in situ is an extraordinarily complex endeavor.

40 and lab-on-a-chip devices to assist in this endeavor.

41 such interactions has remained a challenging endeavor.

42 could be a useful alternative in the present endeavor.

43 sis environments are ideally suited for such endeavor.

44 ity and precision has been paramount in this endeavor.

45 ic strategies for IPF is an important future endeavor.

46 formation has hampered the efficacy of these endeavors.

47 re reliable and valuable for future research endeavors.

48 pping, and in marker-assisted wheat breeding endeavors.

49 hieve animal welfare and quality of research endeavors.

50 l better inform interventions and assessment endeavors.

51 erials impacts success in tissue engineering endeavors.

52 discuss how recent reports will guide future endeavors.

53 ncovalent and covalent hits emerge from such endeavors.

54 This review gives an overview of such endeavors.

55 s is an important problem in many scientific endeavors.

56 in resource dependent and potentially risky endeavors.

57 substituted dendralenes in future synthetic endeavors.

58 d phylogeny can inform a variety of research endeavors.

59 to markedly expedite most strain-engineering endeavors.

60 roaches that we employ in our other research endeavors.

61 al drug design and in other biotechnological endeavors.

62 ctive olefin metathesis in general synthetic endeavors.

63 and social ramifications of their scientific endeavors.

64 thesis, drug discovery, and chemical biology endeavors.

65 ata will be critical to the success of those endeavors.

66 ll individual samples to large collaborative endeavors.

67 l serve as a blueprint for future biological endeavors.

68 it, have created a paradigm for driving such endeavors.

69 clusive platform for focused cancer genomics endeavors.

70 nes, which are of interest in drug discovery endeavors.

71 ing across a broad range of biotechnological endeavors.

72 ll as to offer guidance for future synthetic endeavors.

73 olves time- and resource-intensive heuristic endeavors.

74 ill undoubtedly assist future drug discovery endeavors.

75 to other genomic data collection and sharing endeavors.

76 How far has neuroscience progressed in this endeavor?

77 and African rather than just North American endeavor, (2) realism is better suited to social epidemi

78 To maintain scientific rigour in these endeavors, a comprehensive understanding of statistical

79 s initial definitions to enable these future endeavors, acknowledging that the classification will be

80 epatic tissues continues to be a challenging endeavor and efficient ligand-receptor systems need to b

81 Even though this is a challenging endeavor and PPIs have long been regarded as "undruggabl

82 posed in the target article is a challenging endeavor and will require large-scale data sets with den

83 cient pathogen genomics to multidisciplinary endeavors and describe some of the limitations in resolv

84 lient findings can expedite crop improvement endeavors and the development of nutritionally enriched

85 ntegral part of the foundation of scientific endeavor, and methods and data sharing are complementary

86 Innovation is central to the scientific endeavor, and yet the current system of funding in the U

87 PATRIC's outreach activities, collaborative endeavors, and future research directions is provided.

88 ng discoveries that have resulted from these endeavors, and the future of this stimulating field.

89 r views on NDI chemistry for future research endeavors, and we outline what we believe are the key ob

90 Emerging scientific endeavors are creating big data repositories of data fro

91 Future endeavors are envisioned for the development of an array

92 Although extensive research endeavors are pursued to target ideal molecular sieves a

93 Additional research endeavors are urgently needed to better understand and i

94 last few decades a surge in total synthesis endeavors around the world led to a remarkable collectio

95 We refer to this endeavor as "individualized health." The present article

96 licability to other brain structure-function endeavors as well.

97 have proven unsuccessful to date, hampering endeavors at understanding molecular mechanisms of thera

98 Meta-analysis is essential to this endeavor because large sample sizes are required for det

99 to NF-kappaB mis-regulation, but a difficult endeavor because of the extensive protein-protein interf

100 spectrometry are appealing methods for this endeavor because, potentially, a large amount of informa

101 Here, we contribute to this endeavor by reporting on the development of an (18)F-lab

102 In ENDEAVOR, carfilzomib (56 mg/m(2)) and dexamethasone (Kd

103 nt of nanochemistry, there exists a research endeavor centered around intermetallic nanocrystals, whi

104 rd and punishment in this type of collective endeavors - coined as collective-risk dilemmas - by mean

105 ing CDEPs are suggested: (i) a shared common endeavor connected to the identity of the members, (ii)

106 Pioneering such endeavors could yield constructs that recapitulate disea

107 In such endeavors, DNA is the current building block of choice b

108 Sugar reduction in yogurt is a challenging endeavor due to the changes in taste, flavor, texture, m

109 t because of the inherent difficulty of this endeavor due to the presence of the skull.

110 al importance of collective actions in human endeavors, few works have tackled this topic extensively

111 reventative therapies are complex and costly endeavors focused on individuals likely to develop disea

112 aluable perspective to materials engineering endeavors focused on polymer composites.

113 tion of cardiac imaging and model generation endeavors for mechanistic defibrillation analysis.

114 ey can be widely used to expedite scientific endeavors for the betterment of humankind.

115 nomy are the two most important green energy endeavors for the future.

116 is issue of the JCI, Morath et al. take this endeavor forward.

117 o many of his other scientific and political endeavors, Franklin went on to experiment with oil, spre

118 central goal of migration ecology, and this endeavor has been furthered by genome-scale comparisons.

119 This endeavor has been hampered by the small number of specif

120 However, this endeavor has been hindered because of the lack of specif

121 A critical roadblock to this endeavor has been our inability to produce the prefusion

122 Crucial to this endeavor has been the development of an animal behaviora

123 n between basic science efforts and clinical endeavors has highlighted several additional functional

124 The focus of research endeavors has transferred from detection of a specific a

125 Although numerous research endeavors have been achieved in relation with the graphe

126 ions, significant interdisciplinary research endeavors have been focused on developing materials and

127 igating the environmental concerns, numerous endeavors have been made to seek green and sustainable e

128 Whereas previous endeavors have focused on the Campylobacter jejuni acety

129 This is an ambitious endeavor; however, the C4 pathway evolved from C3 on mul

130 the Center is to lead the self-care research endeavor, improving conceptual clarity and promoting int

131 , hyperarousal, and hypoarousal is a crucial endeavor in biological psychiatry.

132 reness, subjectivity) has become an accepted endeavor in contemporary neuroscience.

133 nic and anthropogenic drivers is a difficult endeavor in such highly complex systems.

134 ical Atlantic Ocean on a transect of the R/V Endeavor in summer 2009 and analyzed for polycyclic arom

135 his perspective intends to cover my fruitful endeavor in the exploration of fluorine chemistry at the

136 a species adapts to its environment is a key endeavor in the study of evolution.

137 plays a critical role in funding scientific endeavors in biomedicine.

138 As we will argue, future endeavors in nucleic acid-based pattern generation will

139 as emerged as one of the foremost scientific endeavors in recent years.

140 ampered by the narrow scope of many research endeavors in terms of both breadth of variables and comp

141 offer a comprehensive assessment of research endeavors in the design and rational synthesis of noble-

142 entially extrapolated to medicinal chemistry endeavors in the taxane family, as well as to the synthe

143 pace is still far from saturated, and future endeavors in this direction will continue to be a valuab

144 n the different directions that the research endeavors in this field need to take in the future and t

145 when the enzyme was purified (a masochistic endeavor) in 1987, leading to the cloning of the Pemt cD

146 ve only been scarcely used in this important endeavor, in marked contrast to their prominent success

147 mple inputs is important for many scientific endeavors, including pharmaceutical, agrochemical, and m

148 stimation in group-averaged data and applied endeavors, including targeted neuromodulation.

149 ew is not meant to be exhaustive, as such an endeavor is impossible, but rather aims to balance bread

150 One of the critical bottlenecks in this endeavor is the computational reconstruction of transcri

151 A major current endeavor is to leverage this knowledge to develop new th

152 simple, and extensible neuron classification endeavor is unique in its detail, utility, and completen

153 At the heart of these endeavors is institutional accountability that ties prog

154 One of the most challenging endeavors is synthesis of molecular nanocarbon.

155 Insight from these endeavors led to critical modifications of our synthetic

156 Success in this endeavor lies in sampling diverse chemical libraries.

157 This endeavor may be accomplished through the study of patien

158 s have changed, of how many things about our endeavor never change, and of how some new ideas are per

159 The results from this endeavor not only led to improved metabolic stability, p

160 The endeavor of constructing natural products--the organic m

161 nvironmental consequences is critical in the endeavor of feeding the growing population sustainably a

162 y shaped how we collectively think about the endeavor of investigating nature.

163 In the endeavor of optimizing the sustainability of bioenergy p

164 combination, significantly complicating the endeavor of predicting the evolutionary dynamics of canc

165 hotocorrosion of these materials can aid the endeavor of realizing stable devices.

166 iteria, which have impeded the long-standing endeavor of standardizing response assessment, are also

167 d as one of the milestones of the scientific endeavor of the 21(st) century.

168 urthermore be used as a model during current endeavors of applying definitions to other transcatheter

169 or nature of g-C3N4 has triggered tremendous endeavors on its structural manipulation for enhanced ph

170 te, has been the focus of intensive research endeavors over the past 2 decades.

171 and physics, has been at the center of this endeavor, particularly during the 1970s and 1980s.

172 coherent analysis pipeline is not a trivial endeavor, particularly for microbiologists with limited

173 The primary endpoint of ENDEAVOR, progression-free survival, has been previously

174 Successful analytical endeavors require collaboration between clinicians, micr

175 Success in this endeavor requires a full understanding of the mechanisms

176 ndertreated, and understudied: each of these endeavors requires efficient and accurate identification

177 We highlight areas of societal endeavor requiring additional efforts to achieve the Aic

178 The randomized TWENTE (The Real-World Endeavor Resolute Versus Xience V Drug-Eluting Stent Stu

179 The TWENTE (Real-World Endeavor Resolute vs Xience V Drug-Eluting Stent Study i

180 This endeavor resulted in the identification of several small

181 In contrast to many other human endeavors, science pays little attention to its history.

182 Valve surgery quality improvement endeavors should focus on a more comprehensive assessmen

183 nish lapses that inevitably occur in complex endeavors such as scientific research.

184 At the forefront of new synthetic endeavors, such as drug discovery or natural product syn

185 discuss experimental design issues for such endeavors, such as how many crosses are required and whi

186 Results from this endeavor suggest that 1,2-cis arabinofuranosides can be

187 Introducing a new vaccine is a large-scale endeavor that can face many challenges, resulting in int

188 restrict androgen synthesis selectively, an endeavor that could benefit from the enhanced understand

189 Photopharmacology is a growing area of endeavor that employs photoswitchable ligands to allow f

190 rofabricated platform, is an active research endeavor that evolved out of the larger field of microfl

191 st in developing biomarkers for efficacy, an endeavor that highlighted the value of dissecting tumor

192 al portions of the delta is now underway, an endeavor that is expected to cost $50-100B over the next

193 ltiple individual human genomes is a complex endeavor that is rapidly gaining importance with the inc

194 chinson-Gilford progeria syndrome (HGPS), an endeavor that many view as a "poster child" for how basi

195 dual differences in cognitive strategies; an endeavor that may be at odds with the normative approach

196 pment of lesions observable on MRI scans, an endeavor that may be facilitated by newborn screening fo

197 ction substrate scope is often a qualitative endeavor that provides general indications of substrate

198 nd-point of an extensive medicinal chemistry endeavor that spans almost three decades.

199 genetic causes within the core eudicots--an endeavor that will have broader implications for the int

200 r offers a critical review of major research endeavors that inform our knowledge of risk to communiti

201 equencing and discuss some of the scientific endeavors that it has enabled.

202 , and addresses future research and training endeavors that might further foster the application of p

203 the cause of this mismatch could be a worthy endeavor, the discrepancy does not appear to question th

204 In this endeavor, the most exploited ligand has been a structura

205 To aid in this endeavor, the present article describes a Model for Unde

206 We endeavor throughout to suggest mechanisms and implicatio

207 ated great potential and success toward this endeavor; thus, in this work, we present a comprehensive

208 to measles control efforts in countries that endeavor to achieve higher levels of population immunity

209 The ICHOM will endeavor to achieve wide buy-in of this set and facilita

210 In the endeavor to associate genetic variation with complex tra

211 In our endeavor to characterize emergent secondary structures,

212 Providers using current guidelines should endeavor to collect practice-based evidence to validate

213 In this framework, we endeavor to correlate state-of-the-art chemical design,

214 Metabolic engineers endeavor to create a bio-based manufacturing industry us

215 Herein, we endeavor to define the essential aspects of quaterpyridi

216 A longstanding endeavor to define the genetic lesions that drive myeloi

217 age-specific models remain useful, we should endeavor to develop a universal model of reading acquisi

218 conversion and molecular nanosciences and we endeavor to discuss the impact of the covalent approach

219 s to influence practice recommendations, and endeavor to elicit and respect family preferences in col

220 le obstacle for bacteria to overcome if they endeavor to endure this endozoonotic cycle.

221 In the present work, we expand this endeavor to examine the accuracy of the measured sedimen

222 Within each section we will endeavor to highlight critical design elements and how t

223 In an endeavor to identify novel vaccine targets, we tested pr

224 Throughout the review, we endeavor to identify the specific HDAC targeted by HDACi

225 dly benefit patients and clinicians in their endeavor to improve management and outcome.

226 Permitting qualified researchers to endeavor to independently reproduce the analyses used in

227 the challenges encountered by scientists who endeavor to map these whole-body connectomes in large an

228 In a collaborative endeavor to minimize maintenance immunosuppression in pe

229 In this study, we endeavor to obtain a global understanding of cell lineag

230 In this work, we endeavor to provide a useful guide for researchers inter

231 iochemistry and Molecular Biology (ASBMB), I endeavor to provide an overview of the extensive history

232 We endeavor to show how this subset of the broader field of

233 Here, we endeavor to summarize the existing data on the genetic a

234 nsitive multimodal imaging techniques should endeavor to transform these group-based findings to indi

235 In the endeavor to understand how our brains enable our multifa

236 one's experiences or explanatory model; (2) Endeavor to understand the individual patient before you

237 Here we endeavor to understand the neural underpinnings of comor

238 as emerged as a crucial aspect of the global endeavor to understand those mechanisms.

239 When mistrust was an issue, physicians endeavored to build a more trusting relationship with th

240 re commonly observed background findings and endeavored to characterize the incidence of spontaneous

241 We have also endeavored to define the interface that governs the asse

242 Therefore, we endeavored to determine the association between the risk

243 We endeavored to determine the pathways involved in the dev

244 native in renal transplantation, and we have endeavored to develop a clinically translatable, belatac

245 Here, we endeavored to develop a DNA four-way junction based elec

246 es in one of our drug discovery programs and endeavored to devise an asymmetric hydrogenation strateg

247 In this work, we endeavored to dissect, using genetic and biochemical app

248 Next, we endeavored to establish a cellular system for testing th

249 Although we have endeavored to follow best practices, there is little pub

250 We have endeavored to gain insight into the 3D architecture of t

251 We endeavored to identify objective blood biomarkers for pa

252 We endeavored to identify objective blood gene expression b

253 We have endeavored to identify, abstract, and present all availa

254 This systematic review endeavored to investigate the effect of soft tissue phen

255 Clinicians endeavored to prevent unmarked deaths by adopting advoca

256 America Clinical Affairs Committee has long endeavored to quantify the value of ID physicians to the

257 Studies have endeavored to reconcile whether dysfunction of neutrophi

258 For decades, protein engineers have endeavored to reengineer existing proteins for novel app

259 In this study, we endeavored to reveal detailed structure-activity relatio

260 In this review, we have endeavored to showcase how a "multitargeted" approach to

261 We endeavored to test these possibilities, focusing on the

262 and BMP signaling along this progression, we endeavored to understand how these pathways are integrat

263 In contrast, the NCI is endeavoring to estimate the increased lung cancer risk f

264 t to coronavirus disease 2019 research while endeavoring to maintain their preexisting agenda.

265 ents were offered as well as future research endeavors to accommodate anticipated environmental chang

266 iative at the Union of Concerned Scientists, endeavors to change this dynamic to strengthen the role

267 e in reciprocal social interactions in joint endeavors to coordinate their caregiving.

268 Synthetic endeavors to create non-natural bioactive small molecule

269 Endeavors to develop highly sensitive, fast, stable and

270 iological validation are necessary in future endeavors to develop TMEM16 CaPLSase inhibitors.

271 tional understanding will assist the ongoing endeavors to enhance crop CO(2) assimilation rate, growt

272 propose a simple centromere size model that endeavors to explain both observations.

273 Resequencing endeavors to find low-frequency variants implicated in c

274 porting and prioritizing meaningful research endeavors to further evaluate these models.

275 hich lead to the CO release, can fuel future endeavors to improve the CO release efficacy of 3-hydrox

276 This review endeavors to provide an introduction to a growing and in

277 This work sets the foundation for future endeavors to resolve key questions in microbial ecology

278 in medicinal chemistry since 2015, and also endeavors to spark the curiosity of investigators who mi

279 ing research in deceased donors, this report endeavors to stimulate the creation of a multi-disciplin

280 in vitro antiplasmodial activity sparked new endeavors to synthesize members of this family of second

281 We suggest the authors' endeavor toward a science of intentional change may bene

282 ization potential may represent an important endeavor toward a wide range of high-performance perovsk

283 oexcited electrons and holes is an important endeavor toward achieving high-efficiency solar energy c

284 Endeavoring toward a transferable, predictive coarse-gra

285 In this review, we describe the main endeavors toward development of treatments that will enh

286 The phase 3 ENDEAVOR trial was a head-to-head comparison of two prot

287 We were successful in this endeavor, using a comprehensive stepwise approach, leadi

288 c instability against dissociation make this endeavor very challenging.

289 ENDEAVOR was a phase 3, open-label, randomised controlle

290 The central challenge in this synthesis endeavor was uniting the hexahydro-2H-pyrazinopyrrolo[2,

291 Critical to these endeavors was a marked improvement in our previously rep

292 To assist this endeavor, we have used an inducible switchgrass cell sus

293 the few reported mechanistic studies on this endeavor were conducted in anesthetized rats.

294 This endeavor will benefit from technical advances in simulta

295 This large-scale endeavor will facilitate the consistent management of fa

296 Such endeavors will also inform the design of therapeutic str

297 ive and engaging visualizations and artistic endeavors will have growing implications on education, c

298 ith existing detection platforms has been an endeavor with few opportunities until now.

299 alysis and interpretation remain challenging endeavors with many limitations and caveats.

300 scularization (TLR), compared with data from Endeavor zotarolimus-eluting stent (E-ZES) trials, adjus