ライフサイエンスコーパス: endocervical

1 itivity of chlamydial testing was similar at endocervical (89%-100%) and self- and clinician-collecte

2 A) and cervical squamous cell carcinoma with endocervical adenocarcinoma (CESC) using data from The C

3 ectomy at our institution for endometrial or endocervical adenocarcinoma over an 11-year interval wer

4 more frequently included the possibility of endocervical adenocarcinoma.

5 HIV-1 infected cells were detected in 51% of endocervical and 14% of vaginal-swab specimens.

6 This study provides evidence that the endocervical and ectocervical epithelia of the human fem

7 Endometrial, endocervical and ectocervical polarized epithelial cells

8 Of 25,081 endocervical and male urethral specimens tested by the P

9 , and the impacts of clinical findings (age, endocervical and urethral inflammation, menses, and gono

10 ED Chlamydia Trachomatis Assay (AMP CT) with endocervical and urine specimens were compared to those

11 retinoic acid maintains the simple columnar endocervical and uterine epithelia.

12 71.8 and 9.5% of screening was performed on endocervical and vaginal specimens, respectively, over t

13 evaluated assay performance for women using endocervical and vaginal swabs as well as urine specimen

14 Swabs of labial, vulvar, perineal, perianal, endocervical, and ectocervical tissue were obtained and

15 and gynecologic history; and urine, vaginal, endocervical, and rectal specimens.

16 The endocervical brush appeared to be better than Dacron swa

17 wall scrapings, ectocervical scrapings, and endocervical brushings were analyzed by flow cytometry.

18 MMPs were overexpressed in endocervical+BVAB CM and CVF from women with BV and were

19 cted lymphocyte-derived cells, we discovered endocervical+BVAB CM and MMPs significantly increased th

20 rom endocervical cells cocultured with BVAB (endocervical+BVAB CM), as well as cervicovaginal fluid (

21 guidance, the cervix was cannulated and the endocervical canal was dilated with an angioplasty ballo

22 -1 RNA levels varied least in specimens from endocervical canal wick and most in cervicovaginal lavag

23 Endocervical canal wicks should be considered as an adju

24 s were collected weekly for 8 weeks from the endocervical canal with wicks and cytobrushes and from t

25 nd vagina and the columnar epithelium of the endocervical canal.

26 to the functional internal os along a closed endocervical canal.

27 herein show that, in MCF-7 breast and ECC-1 endocervical cancer cells, the stimulation of aryl hydro

28 cancer that can be clinically confused with endocervical carcinoma.

29 Here, associations between activated endocervical CD4 + T-cell numbers and higher deoxyadenos

30 The median number of endocervical CD4 lymphocytes/10,000 cells was greater am

31 omen in the placebo group had an increase in endocervical CD4(+) HIV target cells during recovery com

32 Using a polarized endocervical cell culture system, we determined that con

33 they indicate that the presence of a single endocervical cell is as good an indicator of specimen ad

34 the uptake and infection of ectocervical and endocervical cell lines with cell-free fluorescent prote

35 tula is an ineffective device for collecting endocervical cells (for example, odds ratio for comparis

36 35 of 978 specimens) among specimens lacking endocervical cells (P < 0.0001).

37 itivity for C. trachomatis and the number of endocervical cells (P = 0.24).

38 Devices that effectively collect endocervical cells also detect a higher proportion of ab

39 determined that conditioned media (CM) from endocervical cells cocultured with BVAB (endocervical+BV

40 The co-culture of ectocervical and endocervical cells facilitated cellular migration of bot

41 ction of disease and whether the presence of endocervical cells in the smear affects detection of dis

42 ion of the pro-inflammatory cytokine IL-8 by endocervical cells infected with N. gonorrhoeae.

43 The presence of endocervical cells is a valid and convenient surrogate f

44 he two staining methods for detection of the endocervical cells or erythrocytes indicating specimen a

45 Parabasal and endocervical cells showed pattern B spectra.

46 Ectocervical and endocervical cells transfected with miR-negative control

47 A reduction in pmpD null infection of human endocervical cells was associated with a deficiency in c

48 Cervicovaginal secretions and endocervical cells were collected by cytobrush and Inste

49 When we cocultured polarized endocervical cells with HIV-1-infected lymphocyte-derive

50 The endocervical cells' HIV-1 reactivation capacity further

51 s compared the ability of devices to collect endocervical cells, and 19 compared the ability of devic

52 of 655 specimens) among specimens containing endocervical cells, whereas it was 3.6% (35 of 978 speci

53 of specimen adequacy as the presence of many endocervical cells.

54 55 (40.1%) were found to contain one or more endocervical cells.

55 atis LCR test is affected by the presence of endocervical cells.

56 ined and examined at x 400 magnification for endocervical (columnar epithelial or metaplastic) cells

57 seria gonorrhoeae, determined by urethral or endocervical culture) at test of cure (TOC; day 6 +/- 2)

58 rs (FSWs) in the Philippines involved weekly endocervical cultures for Neisseria gonorrhoeae, with tr

59 An endocervical cytobrush for flow cytometry analysis of im

60 Vaginal swabs, menstrual cup, and endocervical cytobrush samples were collected before tre

61 ounders, the levels of all 3 proinflammatory endocervical cytokines were significantly higher in preg

62 was highest among women without mucopurulent endocervical discharge versus those with (relative incre

63 f cervical PCR was highest when mucopurulent endocervical discharge was present (84%) and highest for

64 e to purified rMG309c, vaginal and ecto- and endocervical EC secreted proinflammatory cytokines, incl

65 regulation of chemotactic cytokines by human endocervical, ectocervical, and vaginal epithelial cells

66 rvix, ICOSL expression was restricted to the endocervical epithelia whereas neither miR-155 nor PDL1

67 l barriers of the vaginal, ectocervical, and endocervical epithelia.

68 compared to the parent strain, within A-431 endocervical epithelial cell cultures.

69 effect of N. gonorrhoeae infection in human endocervical epithelial cells (End/E6E7 cells).

70 OMP proteosomes induce cytokine secretion in endocervical epithelial cells (End/E6E7) but not in uret

71 and the cytokine IL-6 by immortalized human endocervical epithelial cells and the production of IL-8

72 d that a subset of both the ectocervical and endocervical epithelial cells become productively infect

73 We found that primary endocervical epithelial cells from several women reactiv

74 ate that N. gonorrhoeae stimulation of human endocervical epithelial cells induces the release of cIA

75 Moreover, epithelial cell lines and primary endocervical epithelial cells released IL-1alpha after C

76 iapoptotic effect of N. gonorrhoeae in human endocervical epithelial cells results from live infectio

77 While endocervical epithelial cells secreted large amounts of

78 m can establish long-term infection of human endocervical epithelial cells that results in chronic in

79 Consistent with this, endocervical epithelial cells were unresponsive to prote

80 iated gonococci and was more vigorous in the endocervical epithelial cells.

81 capable of eliciting chronic inflammation in endocervical epithelial cells.

82 hannels, recapitulating the ectocervical and endocervical epithelial layers.

83 women with BV and were capable of disrupting endocervical epithelial polarization.

84 at can recapitulate the ectocervical and the endocervical epithelial regions of the cervix.

85 s increase HIV-1 infection by disrupting the endocervical epithelium, permitting transmigration of vi

86 ffect of CVF on HIV-1 transmigration through endocervical epithelium, we demonstrated that CVF sample

87 ssociated secreted factors which disrupt the endocervical epithelium.

88 ected in otherwise columnar epithelial-lined endocervical glands.

89 The proportion of activated endocervical HIV target cells out of total T cells incre

90 Antibody subtype analysis of endocervical IgA was consistent with local mucosal produ

91 inflammatory cytokines, but not with altered endocervical immune cells.

92 response in reproductive tract tissues, the endocervical immune responses of women in Bangladesh wer

93 ithelial cell aggregates to model and assess endocervical infection by M. genitalium.

94 that are distinct from those associated with endocervical infection with Neisseria gonorrhoeae or Chl

95 (91%) mucinous adenocarcinomas, encompassing endocervical, intestinal, and endometrioid histological

96 Endocervical levels of interleukin (IL)-1 beta , IL-6, a

97 factors for cervicitis, which is defined as endocervical mucopurulent discharge or easily induced bl

98 activity and expression of CFL1 in PBMCs and endocervical mucosa.

99 n this SIV-macaque model, that an outside-in endocervical mucosal signalling system, involving MIP-3a

100 In the subset of 344 HSS from whom endocervical or urethral specimens were collected for cu

101 simple hyperplasia (n = 2), polyps (n = 4), endocervical polyp (n = 1), and decidualization (n = 2).

102 mpare, in pregnant versus nonpregnant women, endocervical proinflammatory-cytokine expression in resp

103 oped significant sIgA anti-CtxB responses in endocervical samples (P< or =.02).

104 rmat (HC2-M) with these samples and with 911 endocervical samples collected previously.

105 The results of HC2-RCS for endocervical samples from 330 women were compared to tho

106 Stored endocervical samples from a longitudinal cohort study of

107 Endocervical swabs, female urine, and endocervical samples in liquid-based cytology medium wer

108 ng became available midstudy, and unscreened endocervical samples were tested after study completion.

109 uding biopsy collection of observed lesions, endocervical sampling for transformation zone (TZ) type

110 specific IgA was detected in the majority of endocervical secretions (94%) and nasal washes (95%) but

111 The median HIV-1 DNA copy number in endocervical secretions from these women (1.8 HIV-1 DNA

112 Endocervical secretions were analyzed for secretory IgA

113 antibody assay (DFA) of sediment from a spun endocervical specimen culture vial and major outer membr

114 e protein-based PCR of the sediment from the endocervical specimen culture vial.

115 olaou stain for microscopic determination of endocervical specimen quality.

116 itive for the detection of C. trachomatis in endocervical specimens and in urine specimens from men a

117 Endocervical specimens collected for any indication for

118 rhoeae were 100 and 99.4%, respectively, for endocervical specimens compared to 90.0 and 95.9% for fe

119 ith a colposcope for genital lesions, tested endocervical specimens for gonorrhea and chlamydia infec

120 The tests were applied to endocervical specimens from 4,980 women attending family

121 67 (12.8%) were PCR positive, and 41 (7.8%) endocervical specimens from the 525 women were culture p

122 the detection of N. gonorrhoeae from female endocervical specimens obtained from patients attending

123 detection of Neisseria gonorrhoeae in 1,490 endocervical specimens obtained from women attending a s

124 The orders of three endocervical specimens of 3,561 women for Chlamydia trac

125 Six hundred one endocervical specimens were analyzed for Chlamydia trach

126 nd specificity of PCR for C. trachomatis for endocervical specimens were both 100% compared to 100 an

127 est system (Digene, Silver Spring, Md.) with endocervical specimens were compared to those of tissue

128 l specimens were PCR positive, and 19 (9.9%) endocervical specimens were culture positive.

129 ndocervical swab PCR positive, and 15 (7.8%) endocervical specimens were culture positive.

130 A total of 403 female endocervical specimens were evaluated.

131 PCR positive for C. trachomatis, 32 (16.7%) endocervical specimens were PCR positive, and 19 (9.9%)

132 he sensitivities of culturing were 84.8% for endocervical specimens, 92.7% for symptomatic male ureth

133 pecimens, 46.3% of urine specimens, 37.8% of endocervical specimens, and 46% of ectocervical specimen

134 dia trachomatis and Neisseria gonorrhoeae in endocervical specimens.

135 n medium for the diagnosis of gonorrhea from endocervical specimens.

136 the detection of C. trachomatis infection in endocervical specimens.

137 od for detection of N. gonorrhoeae in female endocervical specimens.

138 vical mucus provided some protection for the endocervical surface, by physically trapping virions and

139 ombo 2 assay can be recommended for use with endocervical swab and urine specimens from females, espe

140 simultaneous detection of both pathogens in endocervical swab and urine specimens from females.

141 CT was compared to that of cell culture for endocervical swab and urine specimens from women and ure

142 t of culture was evaluated for 2,236 matched endocervical swab and urine specimens obtained from wome

143 of culturing was evaluated for 2,192 matched endocervical swab and urine specimens obtained from wome

144 positive for N. gonorrhoeae, 23 (12.0%) were endocervical swab PCR positive, and 15 (7.8%) endocervic

145 samples, 82.6% for urine samples, 70.8% for endocervical swab samples, and 82.1% for ectocervical br

146 ne PCR was 93.3%, whereas the sensitivity of endocervical swab specimen culture was 67.3%.

147 R, and all 49 (100%) were positive by either endocervical swab specimen PCR or urine PCR.

148 The resolved sensitivity of the endocervical swab specimen PCR was 86%.

149 cimen, 40 (81.6%) were positive by confirmed endocervical swab specimen PCR, 43 (87.8%) were positive

150 The cellular quality of the endocervical swab specimen used for the detection of Chl

151 %) specimens were positive by culture of the endocervical swab specimen, 40 (81.6%) were positive by

152 for the vaginal swab specimen, 74.3% for the endocervical swab specimen, 61.4% for the urine specimen

153 Plasma samples (obtained weekly) and endocervical swab specimens (obtained thrice weekly) wer

154 imens were tested by culture and AMP CT (717 endocervical swab specimens and 209 urethral swab specim

155 resolved sensitivities of PCR were 92.4% for endocervical swab specimens and 64.8% for female urine s

156 After discrepant analysis, sensitivities for endocervical swab specimens for the EIA and the PACE 2,

157 on by patients, a trained clinician obtained endocervical swab specimens for the same tests.

158 ethral swab and urine specimens from men and endocervical swab specimens from women and thus is well

159 An evaluation of the adequacy of 319 endocervical swab specimens from women attending two inn

160 assay for the detection of C. trachomatis in endocervical swab specimens from women, urethral swab sp

161 ng for C. trachomatis detection in simulated endocervical swab specimens recently distributed interna

162 For the 479 endocervical swab specimens the sensitivity of AMP CT wa

163 The cellular adequacies of 1,633 female endocervical swab specimens were assessed and compared w

164 One urine and four endocervical swab specimens were collected in random ord

165 Of 468 female endocervical swab specimens, 47 (10.0%) had a positive P

166 nsitivities of COBAS AMPLICOR were 89.7% for endocervical swab specimens, 89.2% for female urine spec

167 resolved specificities of PCR were 99.4% for endocervical swab specimens, 99.0% for female urine spec

168 resolved specificities of PCR were 99.5% for endocervical swab specimens, 99.8% for female urine spec

169 Of 415 matched female urine and endocervical swab specimens, there were 49 confirmed inf

170 rachomatis Test has been limited to use with endocervical swab specimens, we conducted an evaluation

171 ) is affected by the cellular quality of the endocervical swab specimens.

172 hose obtained by in vitro culture and PCR of endocervical swab specimens.

173 lected vaginal swab, and clinician-collected endocervical swab) to identify a positive specimen.

174 detect Chlamydia trachomatis rRNA in urine, endocervical swab, and urethral specimens.

175 e urogenital specimens (vaginal swab, urine, endocervical swab, ectocervical brush/spatula) collected

176 Vaginal swab, endocervical swab, ThinPrep PreservCyt, and urine specim

177 cervical Gram stain or yellow mucopus on an endocervical swab.

178 in Dakar (Senegal) were determined by using endocervical-swab-based PCR DNA amplification assays.

179 f indications for testing among women, using endocervical swabbing samples, 2 M sucrose phosphate tra

180 cted cells were detected in 207 (46%) of 450 endocervical swabs and 74 (16%) of 449 vaginal swabs.

181 total of 408 clinical specimens (324 female endocervical swabs and 84 male urine or urogenital swab

182 Data were available from three endocervical swabs and a urine specimen collected from e

183 from each woman, ranging from 4% to 100% of endocervical swabs and from 0 to 71% of vaginal swabs.

184 tandard, that LCR and PCR tests performed on endocervical swabs and urine are superior to PACE 2 test

185 ae and Chlamydia trachomatis in urethral and endocervical swabs and urine samples from men and women

186 s were detected by use of the combination of endocervical swabs and urine specimens.

187 Endocervical swabs from 1025 female sex workers in Kampa

188 In a comparison of two sampling methods, endocervical swabs were more sensitive than cervicovagin

189 99.0% for vaginal swabs, 100% and 99.4% for endocervical swabs, 100% and 99.6% in ThinPrep samples,

190 collected vaginal swabs, 81.5% and 98.3% for endocervical swabs, 77.8% and 99.0% for female urine, an

191 or vaginal swabs, 93.4% (88.3% to 96.4%) for endocervical swabs, and 92.9% (87.8% to 96.0%) for femal

192 e urine samples, male urethral swabs, female endocervical swabs, and self-collected and clinician-col

193 nd 96.1% (92.2% to 98.1%) for vaginal swabs, endocervical swabs, female urine samples, and male urine

194 Endocervical swabs, female urine, and endocervical sampl

195 Evaluations included three primer sets, endocervical swabs, vaginal swabs and urine, and various

196 ed with a proprietary cervical brush or with endocervical swabs.

197 ectively; 93.3% (95% CI, 89.6% to 95.7%) for endocervical swabs; and 92.5% (95% CI, 88.7% to 95.1%) f

198 ectively; 97.0% (95% CI, 91.5% to 99.0%) for endocervical swabs; and 96.6% (95% CI, 90.6% to 98.8%) f

199 l tract-derived cell lines and primary human endocervical tissue can support direct transcytosis of c

200 ble levels across vaginal, ectocervical, and endocervical tissues; however, endocervical Vdelta2 T ce

201 21 women and 2514 men) received a TV NAAT on endocervical, urethral, or urine specimens.

202 ea in females demonstrated sensitivities for endocervical, vaginal, and urine samples of 100.0%, 100.

203 ia in females demonstrated sensitivities for endocervical, vaginal, and urine samples of 97.4%, 98.7%

204 cervical, and endocervical tissues; however, endocervical Vdelta2 T cells showed higher inflammatory