ライフサイエンスコーパス: endothelia

1 cessfully quantified (i.e. cardiomyocytes or endothelia).

2 APOL1 is found in human kidney podocytes and endothelia.

3 creases in CD39 mRNA and immunoreactivity on endothelia.

4 in development of the adjacent epithelia and endothelia.

5 -associated endothelia compared with resting endothelia.

6 ssed widely in organ and tumor microvascular endothelia.

7 cross cell plasma membranes in epithelia and endothelia.

8 ts involved in the maintenance of functional endothelia.

9 od-borne protein passage through fenestrated endothelia.

10 TFIID was the converse of YY1, in different endothelia.

11 ow different patterns of binding between the endothelia.

12 sulfate on the luminal surface of capillary endothelia.

13 characterized by retracted cells and thinned endothelia.

14 and abundant staining for COX-2 in infected endothelia.

15 rine, mammary, placenta, and coronary artery endothelia.

16 ce/differentiation of central nervous system endothelia.

17 resulted in increased adhesion to activated endothelia.

18 sive signal for PMN binding to microvascular endothelia.

19 rcellular junctions of various epithelia and endothelia.

20 ls in tubules, whereas Tie-2 is expressed by endothelia.

21 onto the vessel wall and transmigrate across endothelia.

22 d channels are also described in fenestrated endothelia.

23 and stellate cells, but not from sinusoidal endothelia.

24 is through the VEGFR-3 receptor on lymphatic endothelia.

25 ein of caveolae membranes in fibroblasts and endothelia.

26 and enter Kupffer cells, but not sinusoidal endothelia.

27 rptive endocytosis and transcytosis in brain endothelia.

28 e ischemic injury to neurons, microglia, and endothelia.

29 ally be involved in their arrest on inflamed endothelia.

30 d descending thin limbs as well as capillary endothelia.

31 which mimics adhesion of lymphocytes to CNS endothelia.

32 ng limb of Henle epithelia and in vasa recta endothelia.

33 lining cells, portal tract, and central vein endothelia.

34 ed in erythrocytes and various epithelia and endothelia.

35 ating paracellular transport of large vessel endothelia.

36 ncontact coculture with human umbilical vein endothelia.

37 g metastasis, tumor cells adhere to vascular endothelia.

38 the relevance of these findings to arterial endothelia.

39 Cx26 staining was confined to capillary wall endothelia.

40 the alloimmunogenicity of nearby uninfected endothelia.

41 sponse markedly attenuated in CD36-deficient endothelia.

42 tween glycoligands on CTCs and E-selectin on endothelia.

43 ting T cells firmly adhere to DC-HIL-treated endothelia.

44 attenuated in CD36-deficient compared to WT endothelia.

45 dentity most closely related to human kidney endothelia.

46 , is expressed in the vascular and lymphatic endothelia.

47 is important for neutrophil firm adhesion to endothelia.

48 ed endogenous erythropoiesis damage vascular endothelia.

49 dothelia than on rapidly proliferating tumor endothelia.

50 in expressed strongly in tumor microvascular endothelia.

51 tigens enriched in tumor versus nonmalignant endothelia.

52 f paracellular permeability in epithelia and endothelia.

53 o both pulmonary and extrapulmonary vascular endothelia.

54 r selective removal of IL-1R in microglia or endothelia.

55 regulation of tight junction proteins in the endothelia.

56 tes IL-8 production in the LECs of lymphatic endothelia.

57 c significantly diminished albumin uptake by endothelia.

58 ect eNOS expression and activity in vascular endothelia.

59 umber of subepithelial cell types, including endothelia.

60 logies, included (1) angioblasts, (2) mature endothelia, (3) hepatic stellate cell precursors, (4) ma

61 impaired in extravasation through quiescent endothelia, a phenomenon that could contribute to the di

62 reby TRAIL blocks DR5 signaling in quiescent endothelia, acting as gatekeeper of the vascular barrier

63 ack morphologically identifiable caveolae in endothelia, adipocytes, smooth muscle cells, skeletal mu

64 t monocyte adhesion on early atherosclerotic endothelia and (2) ILDV peptide interferes with VLA-4 bi

65 channel aquaporin-1 (AQP1) in microvascular endothelia and aquaporin-4 (AQP4) in airway epithelia.

66 Brain microvascular endothelia and brain endothelial cells expressed all of

67 art, by stimulating VEGF expression in tumor endothelia and by recruiting pericytes to neovessels.

68 ry, view tumor cell adhesion to blood vessel endothelia and cancer cell aggregation as corresponding

69 ht to determine the RNA profile of activated endothelia and delineate the pathways by which these end

70 e shown that a soluble activity derived from endothelia and dependent on STAT3 is critical for suppre

71 e elucidate the angiogenic activities of the endothelia and differential interactions with perivascul

72 ents of the basement membranes that separate endothelia and epithelia from the underlying tissue.

73 induced IFN responses specifically in brain endothelia and epithelia of mice.

74 hanical probe-induced micro-wounding of both endothelia and epithelia suggests that ventral lamellipo

75 let-activating factor receptor expression on endothelia and epithelia, which led to reduced bacterial

76 ll mice expressed significantly more PAFr on endothelia and epithelia.

77 eins, critical for maintenance of glomerular endothelia and filtration barrier functional integrity,

78 for leukocyte extravasation through vascular endothelia and for T-cell activation.

79 GH), and placental lactogen are expressed by endothelia and have angiogenic effects.

80 tradiol exposure to internal thoracic artery endothelia and human arterial endothelia in culture stim

81 release from human internal thoracic artery endothelia and human arterial endothelia in culture.

82 tionary relationships between diverse vessel endothelia and identify the myelinating and non-myelinat

83 Bmx is expressed mainly in arterial endothelia and in myeloid hematopoietic cells.

84 tive origin from other TME components (e.g., endothelia and macrophages).

85 105), known to be expressed on proliferative endothelia and mesenchymal stem cells, was diminished in

86 one marrow transplantation, such as vascular endothelia and microglia, to transduce microglial activa

87 and enhanced interleukin (IL)-1 signaling in endothelia and neurons.

88 where it localized principally to choroidal endothelia and pericytes and less frequently to the reti

89 displayed leukocyte adhesion to the vascular endothelia and petechial hemorrhages throughout the brai

90 lium attached to the interstitial matrix, to endothelia and phasic lymphatic smooth muscle that act a

91 Tetraspanin CD151 is highly expressed in endothelia and reinforces cell adhesion, but its role in

92 ccurring along portal tract and central vein endothelia and scattered bile duct epithelial cells and

93 , migration, and differentiation of vascular endothelia and smooth muscle cells.

94 waned in most areas but remained in vascular endothelia and the dentate gyrus.

95 TAT-3 activation were observed, the first in endothelia and the second in hepatocytes.

96 tinel cells of the immune system, leading to endothelia and thrombocyte dysfunction and neurological

97 ch binds to alphavbeta3/5 integrins on tumor endothelia and tumor cells, and a cryptic CendR motif (R

98 ophysical characteristics of Schlemm's canal endothelia and/or their immediate underlying extracellul

99 aran sulfate purified from primary lymphatic endothelia, and activation of lymphatic endothelial Erk1

100 ates communication between the epithelia and endothelia, and functions to support a variety of proces

101 th and patterning of the renal epithelia and endothelia, and in the maintenance and repair of the adu

102 i)PD-1(hi)), vigorous recruitment to injured endothelia, and increased effector responses in vivo.

103 by oligodendrocytes, neurons, microglia, and endothelia, and MHC class II is expressed only by microg

104 n, implicating astrocytes, oligodendrocytes, endothelia, and microglia in ALS pathophysiology.

105 ession was relatively enriched in microglia, endothelia, and pericytes of the human brain.

106 types of mammalian cells including cerebral endothelia, and quantified leptin binding and endocytosi

107 on was inhibited in Ndst1-silenced lymphatic endothelia, and scratch-assay responses to VEGF-C and FG

108 actin dynamics, biomechanical properties of endothelia, and signaling pathways, such as GTPase activ

109 on neutrophils, smooth muscle, hepatocytes, endothelia, and some epithelia.

110 31- and Tie-2-positive peritubular capillary endothelia, and some of the alpha SMA-positive cells exp

111 ntrolling the interaction among tumor cells, endothelia, and stromal matrix.

112 s (PMN, neutrophils) migrate across vascular endothelia, and such transmigration has the potential to

113 far less well defined than the epithelia and endothelia, and we understand only a fraction of their f

114 channel aquaporin-1 (AQP1) in microvascular endothelia, AQP4 in airway epithelia, and AQP5 at the ap

115 These data indicate that human endothelia are able to produce active vitamin D.

116 osal tissue, such as the lung and intestine, endothelia are anatomically positioned in close proximit

117 ulation of plasmalemmal vesicles of vascular endothelia are described.

118 Barrier functions across epithelia and endothelia are essential for homeostatic tissue regulati

119 in the maintenance of functionally quiescent endothelia are starting to be identified and are a combi

120 In blood vessels, endothelia are submitted to constant shear effects and a

121 Epithelia and endothelia are the most common barrier-forming cells.

122 These data define STAT3 signaling within endothelia as a critical antiinflammatory mediator and p

123 fluorescence of MitoTracker in microvascular endothelia as a result of reduced mitochondrial mass.

124 ules and activate macrophages, NK cells, and endothelia as well as participate in organ-specific auto

125 ice, there was clear dependence on IL-1R1 on endothelia-associated transcripts including Lrg1, Icam1,

126 studied whether PTPmu, in pulmonary vascular endothelia, associates with and/or regulates both the ty

127 Expression of ZO-1 in WT endothelia at P14 was diffuse and localized to the basol

128 ial cells closely resemble lymphatic (valve) endothelia at the molecular level, suggesting plasticity

129 Notwithstanding endothelia being non-excitable in nature, the hypothesis

130 atenin-Dll4/Notch signaling cascade in tumor endothelia, blocking an angiogenic and favoring a quiesc

131 ogically active ET ligand, begins in cardiac endothelia, both arterial and endocardial, at initiation

132 ontrast, connexin43 was undetectable in most endothelia but extremely abundant in small numbers of ce

133 aring of globotriaosylceramide from vascular endothelia but little effect on proteinuria or progressi

134 cadherin-10, is expressed in BBB and retinal endothelia, but not in the leaky microvessels of brain c

135 irectly acting on the vascular and lymphatic endothelia, but they also can affect distal sites.

136 ptor (CysLT(1)) is induced in human vascular endothelia by interleukin-1beta.

137 GFBP2) secreted by metastatic cells recruits endothelia by modulating IGF1-mediated activation of the

138 brain tissue sections stained for markers of endothelia (CD34) and BBB integrity (fibrinogen and immu

139 another potential pathway for vasculitis as endothelia cell IL-6 may stimulate immune cell responses

140 Endothelia-cell injury may result in an imbalance in end

141 dentification of IL-6 production in vascular endothelia cells after alloimmune activation reveals ano

142 hages but not by myogenic cells or capillary endothelia cells in injured muscles.

143 ys an important role in tight junction among endothelia cells, leukocyte trafficking, and immune resp

144 ia and delineate the pathways by which these endothelia communicate within the brain to influence key

145 nduced to highest levels in tumor-associated endothelia compared with resting endothelia.

146 aled red blood cell congestion within intact endothelia, consistent with circulatory collapse and pla

147 P2 engagement on peripheral immune and brain endothelia contributes to the deleterious effects of SE,

148 -regulation of PAFr on chronically activated endothelia could contribute to increased bacterial invas

149 ology, we show that IL-1-dependent microglia-endothelia cross talk is necessary for eliciting this sp

150 In other studies, lymphatic endothelia cultured ex vivo from Ndst1 gene-targeted mic

151 ental sensing across the spectrum of enteric endothelia, demonstrating that endothelial AHR signallin

152 Corneal endothelia derived from mice and humans were treated wit

153 Using gene profiling, we identified that the endothelia-derived chemokine ligand CXCL10 mediated beha

154 is expressed, in particular, in endocardial endothelia during fetal valve morphogenesis and is key i

155 hich is important for neutrophil adhesion to endothelia during inflammation.

156 renal Ent1 and Adora2b expressed on vascular endothelia effectively prevented a postischemic no-reflo

157 ms, the kidney and the liver, and cells from endothelia, epithelia, and the bone marrow compartment.

158 lucose reabsorption, and the tight capillary endothelia (especially in the brain).

159 e brain after RSD and Ptgs2 was localized to endothelia, especially within the hypothalamus.

160 Loss of AHR in endothelia exacerbates lung damage and promotes the infi

161 Swine aortic arch endothelia exhibited elevated ROS, NOX4, HIF-1alpha, and

162 IFN-gamma thus alters gene expression by endothelia exposed to B. burgdorferi in a manner that pr

163 in vivo in mouse and swine aortic arch (AA) endothelia exposed to chronic disturbed flow, and in mou

164 uman lung microvascular ECs as well as other endothelia express catalytically active NEU1 and NEU3.

165 ng cell lines and human brain microcapillary endothelia expressing high levels of endogenous receptor

166 beta4BM in hCLCA1, which is not expressed in endothelia, failed to interact with beta4 integrin.

167 pecifically, as the ureteric bud bifurcates, endothelia form across the bifurcation site as the cap m

168 In the absence of the dorsal aorta, endothelia from an alternate source are recruited by pod

169 n homogenates or the particulate fraction of endothelia from bovine or rabbit.

170 d function of the tumor vasculature and that endothelia from different tissues vary in their ability

171 enosine monophosphate (cAMP) was measured in endothelia from fresh and incubated corneas, and adenyly

172 n were similar in primary cultures of aortic endothelia from wild-type and from AQP1-null mice, cell

173 Retinal endothelia have the capacity to express AQP1, though int

174 TLR) 4 expressed in human lung microvascular endothelia (HMVEC-Ls) to open the paracellular pathway t

175 of Adora2b in tubular epithelia or vascular endothelia implicated endothelial Adora2b signaling in p

176 ) in culture, and is expressed on continuous endothelia in all tissues.

177 present not only in neurons, but in cerebral endothelia in Alzheimer's disease caused by certain APP

178 of IL-4 signaling, by tumor cells and tumor endothelia in CNS lymphomas.

179 horacic artery endothelia and human arterial endothelia in culture stimulated NO release within secon

180 horacic artery endothelia and human arterial endothelia in culture.

181 to identify peptides that bound the vascular endothelia in diseased and wild-type mice.

182 ded renal endotheliosis, loss of fenestrated endothelia in endocrine organs, and hemorrhages.

183 mmunohistochemical C4d staining of capillary endothelia in formalin-fixed, paraffin-embedded right ve

184 We found that vascular endothelia in inflamed areas of lacrimal gland expressed

185 ular matrix that underlies all epithelia and endothelia in multicellular animals.

186 lasma extravasation in postcapillary venular endothelia in NEP-/- mice, which was reversed by recombi

187 knockout of the receptor for ANP in vascular endothelia in order to distinguish the effects of ANP-de

188 wn, however, is the role of immune-activated endothelia in regulating the physiological and behaviora

189 Lung endothelia in the arteries, capillaries, and veins are h

190 signaling in the maintenance of neurons and endothelia in the central nervous system.

191 ot all, of the thoracic and abdominal aortic endothelia in the form of maculae at cell-cell appositio

192 tein tau that is expressed in lung capillary endothelia in the host-pathogen interaction.

193 elevation that matched beta-actin-expressing endothelia in the vascular wall.

194 rins, blocked the adhesion of these cells to endothelia in vitro and in vivo as well as their homing

195 the adhesion of mural cells to proliferating endothelia in vitro and in vivo, thereby inducing apopto

196 cells proliferated faster and produced more endothelia in vivo than their otherwise isogenic trisomi

197 detail divergence of vascular and sinusoidal endothelia, including a distinct transcriptional profile

198 ial for transcytosis of ligands across tight endothelia, including the blood-brain barrier.

199 issue-protective transcriptional networks in endothelia, including the vasoactive apelin-APJ peptide

200 tion in which FRNK expression in microvessel endothelia increased vascular permeability.

201 dynamic forces are detected and converted by endothelia into a sequence of biological and even pathol

202 on page 1234) reports how TLR2 expression by endothelia is locally upregulated by the action of activ

203 IV (DPP IV) expressed on rat lung capillary endothelia is shown here to be an adhesion receptor for

204 gic nerve terminals and by NOS-3 in vascular endothelia, is probably a physiological vasodilator in t

205 whether the gene is transcribed in different endothelia, is related to the balance between activating

206 ng miloDE, we identify a transient hemogenic endothelia-like state in mouse embryos lacking Tal1 and

207 dissemination is bacterial interaction with endothelia lining blood vessels, which is physically cha

208 Here we tested the hypothesis that endothelia lining these vessels can be harnessed to crea

209 e the replacement of MAdCAM-1 by PNAd in HEV endothelia, lymphocytes could efficiently home to PPs in

210 rtension as well as other disorders in which endothelia may be damaged.

211 reciprocal interaction between podocytes and endothelia may provide opportunities for therapeutic int

212 The antigen cross-presentation ability of endothelia may therefore contribute to the specificity o

213 rare (<5%) cells, such as Tie2:Cre(+) brain endothelia/microglia (76% validated by expression patter

214 ion in different tissues--including vascular endothelia, myeloid cells, and hepatocytes--revealed a s

215 Systematic deletion of HIF1A in the lungs, endothelia, myeloid cells, or pulmonary epithelia linked

216 power of phage display for mapping vascular endothelia natively in tissue and for achieving vascular

217 In endothelia, NO is synthesized by endothelial NO synthase

218 ere Gpr124 conditional knockout (CKO) in the endothelia of adult mice did not affect homeostatic BBB

219 enomenon shared by human arterial and venous endothelia of both fetal and adult origin.

220 The endothelia of Col12a1(-/-), Col14a1(-/-), and compound C

221 led a spread of phenotypic diversity between endothelia of distinct developmental origins and organs.

222 RNA-Seq splicing data from the corneal endothelia of FECD patients and controls reveal hundreds

223 gene with overexpression of cNOS protein in endothelia of gastric mucosal vessels.

224 3 was constitutively present in the vascular endothelia of large and small vessels.

225 Expression of ICAM-1 in aortic endothelia of LOTG mice was increased severalfold.

226 The endothelia of normal and Fuchs'-affected corneas were st

227 xhibits limited capacity to divide while the endothelia of other species, such as rabbit, divide in v

228 dothelial venules but is also present on the endothelia of other vessels.

229 Metastatic tumor cells attached to the endothelia of pulmonary pre-capillary arterioles and cap

230 heir cognate antigens for targeting vascular endothelia of specific organs in vivo.

231 ntaining vesicles dock preferentially to the endothelia of target organs.

232 aveolae and transendothelial channels in the endothelia of these vascular beds.

233 irculation and that specifically bind to the endothelia of tumor blood vessels.

234 ce of infected erythrocytes to microvascular endothelia of various organs, including the placenta, th

235 , was increased approximately 2-fold each in endothelia, oligodendroglia, astrocytes, and axons of th

236 intercellular adhesion molecules (ICAMs) on endothelia or antigen-presenting cells.

237 When endothelia or astrocytes are plated onto these substrate

238 onto these substrates, confluent domains of endothelia or astrocytes grow on the poly(L-lysine) doma

239 cell type sporozoites use for extravasation, endothelia or Kupffer cells, we quantified sporozoite ad

240 Additional studies in endothelia overexpressing full-length A2BR revealed func

241 In human and rabbit endothelia, p53 and p16INK4 were localized to the cytopl

242 ng in line with its downregulation in glioma endothelia, potentially implicating Cyp1b1 in other brai

243 While both viruses infect microglia and endothelia primarily in the white matter areas of the CN

244 timuli (LPS, IL-1alpha, TNF-alpha, hypoxia), endothelia produce and secrete a small, stable epithelia

245 lineage restriction to hepatoblasts, mature endothelia produced differentiation into hepatocytes, an

246 We hypothesized that adenosine signaling to endothelia provides a paracrine loop for regulated expre

247 anding of endorepellin signaling in vascular endothelia, providing insight into the temporal complexi

248 ly described mechanism of VEGF inhibition in endothelia required the release of VEGF-R1 intracellular

249 anotransduction mechanisms by which vascular endothelia respond to local atherorelevant hemodynamics

250 Fluid flow across various endothelia results in a variety of intracellular and ext

251 However, vascular endothelia, retinal pigment epithelia, Muller cells, and

252 IL-1 receptor (IL-1R) in either microglia or endothelia reveal that IL-1-dependent signaling between

253 on of the genes expressed in lung and kidney endothelia revealed numerous differences.

254 Additional studies in confluent endothelia revealed that gravin functionally couples to

255 lectively, social stress stimulated specific endothelia RNA profiles associated with increased cell a

256 r on erythrocytes (strain ThCD59(RBC)) or on endothelia (strain ThCD59(END)).

257 disturbed flow, and in mouse carotid artery endothelia subjected to surgically induced acute disturb

258 the permeation of xenobiotics through tight endothelia such as the blood-brain barrier.

259 tion of lytic injury to uninfected bystander endothelia, suggesting multiple mechanisms by which this

260 , the presence of LYVE-1 in liver sinusoidal endothelia suggests that LYVE-1 has functions beyond the

261 n any other reproductive or non-reproductive endothelia tested, ERbeta was augmented by pregnancy in

262 a radiosensitizing effect on normal cardiac endothelia than on rapidly proliferating tumor endotheli

263 angiogenic growth factors or on neighboring endothelia that are affected by these agents.

264 d in both neurons and cerebral microvascular endothelia that binds Abeta.

265 biting the antiapoptotic effects of Ang-1 on endothelia that express the Tie-2 receptor.

266 elated with heightened permeability of other endothelia, the objective of this study was to test the

267 re compared in both human and rabbit corneal endothelia: the tumor suppressors, pRb, p53, and p16INK4

268 is widely expressed by differentiating renal endothelia, this study is consistent with the hypothesis

269 which promote chemotaxis of granulocytes and endothelia through binding to CXC Receptor 2.

270 that CD44 mediates several of its effects on endothelia through modulation of adhesion protein expres

271 e paracellular pathway in pulmonary vascular endothelia through protein tyrosine phosphorylation.

272 cular meshwork (TM) and Schlemm's canal (SC) endothelia to aqueous humor outflow resistance.

273 differences between tumor and normal tissue endothelia to induce acute vascular shutdown in tumors.

274 ERTK-expressing monocytes migrate across the endothelia to localize into tissue sites and regional ly

275 Astroglia interact with cerebral endothelia to maintain the blood-brain barrier.

276 activate disease tolerance pathways in lung endothelia to prevent tissue damage.

277 ts of the extracellular matrix can stimulate endothelia to trigger recognition of injury in the initi

278 Fc molecules by HULEC-5A lung microvascular endothelia transfected with GFP fusion proteins of human

279 complexes too large to cross the continuous endothelia under physiological conditions.

280 specifically to the inflamed carotid artery endothelia under physiological flow conditions and to be

281 B. burgdorferi exploits Fn to interact with endothelia under physiological shear stress, using recen

282 cells such as leukocytes and platelets with endothelia under vascular shear stress requires mechanic

283 conditionally deleted in restricted vascular endothelia using a novel endothelial Cre transgenic line

284 sic PKA demonstrated an inhibitory effect on endothelia vascular-like structure formation.

285 sin cell adhesion molecule 1 on the DLN high endothelia venules, and production of IL-6 and CC chemok

286 nteraction of platelets with neutrophils and endothelia was associated with TXA(2) formation, with de

287 ular localization of PMP22 in cultured brain endothelia was confirmed by internalization with ZO-1 af

288 rditis, the upregulation of PD-L1 on cardiac endothelia was dependent on T-cell-derived interferon-ga

289 g perfusion in mice with genetically labeled endothelia, we compared peritubular capillary number and

290 icroscopy, rat aortic and pulmonary arterial endothelia were found to express all 3 connexin types, w

291 endothelial supernatants obtained after the endothelia were infected with P. aeruginosa possessing a

292 All three endothelia were screened for transcription factors that

293 Pmu is expressed in human pulmonary vascular endothelia where it directly binds to VE-cadherin and re

294 channel protein expressed widely in vascular endothelia, where it increases cell membrane water perme

295 xpressed in, and secreted from, the vascular endothelia will be endocytosed by underlying neurons and

296 characteristics of both blood and lymphatic endothelia with a lymphatic phenotype predominating.

297 o incur cytoxic effects and apoptosis of BBB endothelia with an impairment of barrier functionality.

298 Treatment of human brain endothelia with glutamate or selective, mGluR group I or

299 ly attenuated by pretreatment of human brain endothelia with selective mGluR antagonists.

300 ons were present in the glomerular capillary endothelia without any associated inflammatory response.