ライフサイエンスコーパス: energy metabolism

1 cerebral metabolism as well as for systemic energy metabolism.

2 pressure, plasma markers of inflammation, or energy metabolism.

3 isturbances due to temporarily altered brain energy metabolism.

4 oral and cognitive consequences of disrupted energy metabolism.

5 dormancy, freezing tolerance and changes in energy metabolism.

6 mitochondria highly specialized for cellular energy metabolism.

7 ntial for broad applications in the study of energy metabolism.

8 trate utilization-is a critical component of energy metabolism.

9 f anabolic and catabolic reactions including energy metabolism.

10 and play predominantly an anorectic role in energy metabolism.

11 of proteins implicated in insulin action and energy metabolism.

12 ivores exhibit seasonal adjustments in their energy metabolism.

13 ed processes like hypertrophy, fibrosis, and energy metabolism.

14 of insulin signaling and Foxo by regulating energy metabolism.

15 tanding of the physiology of food intake and energy metabolism.

16 after metamorphosis but contribute little to energy metabolism.

17 or nuclear receptors that regulate lipid and energy metabolism.

18 ls face multiple restrictions on glucose and energy metabolism.

19 ntial for broad applications in the study of energy metabolism.

20 (TGR5) promotes adipose tissue browning and energy metabolism.

21 icing, ribosomal dysregulation and disturbed energy metabolism.

22 (NAD(+)) is a critical coenzyme for cellular energy metabolism.

23 show elevated expression of genes underlying energy metabolism.

24 mitochondria highly specialized for cellular energy metabolism.

25 ligands, may regulate endocrine function and energy metabolism.

26 m in regulating whole-body thermogenesis and energy metabolism.

27 olites that are central to the regulation of energy metabolism.

28 nitine shuttle associated with mitochondrial energy metabolism.

29 chondrial lipid CL to TCA cycle function and energy metabolism.

30 ive thermogenesis, lipolysis, and whole-body energy metabolism.

31 nt protein phosphorylation, and dysregulated energy metabolism.

32 l activity, vascular tone, inflammation, and energy metabolism.

33 anisms of cardioprotection and modulation of energy metabolism.

34 me for redox reactions, making it central to energy metabolism.

35 hat aging and cancer are diseases related to energy metabolism.

36 et-induced changes of the gut microbiota and energy metabolism.

37 hormones that regulate different aspects of energy metabolism.

38 of PC1 expression profoundly alters cellular energy metabolism.

39 f the p53 family, has been shown to regulate energy metabolism.

40 s via secreted factors to influence systemic energy metabolism.

41 ons in C1QBP cause a defect in mitochondrial energy metabolism.

42 f genes related to the transport process and energy metabolism.

43 rocesses, such as DNA repair, autophagy, and energy metabolism.

44 may serve unique functions to alter hepatic energy metabolism.

45 n adipogenesis, and act to modulate systemic energy metabolism.

46 suggesting decreased resource efficiency of energy metabolism.

47 with fields of multiple indices of cellular energy metabolism.

48 rogenase (GAPDH) is a key enzyme involved in energy metabolism.

49 a potential link between bone remodeling and energy metabolism.

50 irium, consistent with acutely altered brain energy metabolism.

51 ink between mechanical events and underlying energy metabolism.

52 ersection with amino acid, carbohydrate, and energy metabolism.

53 to all layers and regions: inflammation and energy metabolism.

54 ed G-protein coupled receptor that regulates energy metabolism.

55 s a key regulator of cellular and whole-body energy metabolism.

56 f ex vivo mitochondrial function and in vivo energy metabolism.

57 ion, erythropoietin production, and cellular energy metabolism.

58 scription is crucial for regulating cellular energy metabolism.

59 ntrinsic mechanism to regulate mitochondrial energy metabolism.

60 t the crossroads of glycolytic and oxidative energy metabolism.

61 glycerol), energy (ATP), and an inhibitor of energy metabolism 2-deoxy-D-glucose (DeOGlc) + sodium io

62 re continuous oxygen provision for efficient energy metabolism(2).

63 ts that several major pathways including (1) energy metabolism, (2) protein degradation, (3) fatty ac

64 Vps34 inhibition alters cellular energy metabolism, activating the AMPK pathway in liver

65 g evidence that LSCs harbor a characteristic energy metabolism, adhesion molecule composition, as wel

66 ion to the Notch and Wnt signaling pathways, energy metabolism also regulates intestinal stem cell (I

67 tein required for mitochondrial function and energy metabolism and AD risk.SIGNIFICANCE STATEMENT Mit

68 , a better understanding of the link between energy metabolism and antibiotic-induced mycobacterial d

69 rameter resolution allows to explore altered energy metabolism and antiviral defence by tagged mitoch

70 )H are all redox cofactors with key roles in energy metabolism and are substrates for several NAD-con

71 n transport chain that functions in cellular energy metabolism and as a membrane antioxidant.

72 nucleotide (NAD(+)) plays a critical role in energy metabolism and bioenergetic homeostasis.

73 ays of metabolism, playing a pivotal role in energy metabolism and biosynthesis.

74 on terminals may be important in maintaining energy metabolism and biosynthetic activities mediated b

75 hat is linked to dysfunctional mitochondrial energy metabolism and caused by adenylate kinase 2 (AK2)

76 ogether, these results suggest links between energy metabolism and cellular physiology, morphology, a

77 he interaction between novel drugs targeting energy metabolism and classical first and second line an

78 /calcitonin signaling in CTR-POMC neurons on energy metabolism and demonstrate the need for sex-speci

79 thus reveal an important connection between energy metabolism and ECM assembly.

80 Such negative effects of nanoplastics on energy metabolism and efficiency could be detrimental un

81 We reveal a link between energy metabolism and epigenetic control of cell state t

82 0.05) changes in intermediate metabolites of energy metabolism and fatty acid and amino acid metaboli

83 for clinically relevant (13)C MRS studies of energy metabolism and further provides opportunities for

84 ensor of lactate, which functions to connect energy metabolism and innate immunity.

85 le, promotes weight loss and improvements in energy metabolism and insulin in adults with BMI 19-27 k

86 c maturation by inducing cyclic synthesis of energy metabolism and insulin secretion effectors, inclu

87 ng the fibrotic reaction, immune regulation, energy metabolism and is a novel therapeutic target in P

88 e novel findings highlight the importance of energy metabolism and its dynamic regulation in the evol

89 he Lmna gene, have antagonistic functions on energy metabolism and life span.

90 enesis, skeletal muscle development, growth, energy metabolism and lipid metabolism, which may be ass

91 observations indicate a relationship between energy metabolism and membrane composition.

92 hypothesized that formate might affect both energy metabolism and microaerobic survival in C. jejuni

93 the first comprehensive characterisation of energy metabolism and mitochondrial efficiency in equine

94 aptic mitochondria and is linked to neuronal energy metabolism and mitochondrial function.SIGNIFICANC

95 light the role of TRAP1 in the regulation of energy metabolism and mitochondrial quality control.

96 cterized by impaired brain iron homeostasis, energy metabolism and mitochondrial trafficking.SIGNIFIC

97 Autophagy, besides ensuring energy metabolism and organelle renewal, is crucial for

98 insic fluorescent species from a distinctive energy metabolism and oxidized lipids, as seen with Thir

99 ely), and to examine the association between energy metabolism and postpartum weight retention (PPWR)

100 uction of a myokine, irisin, improves kidney energy metabolism and prevents kidney damage.

101 y interacting global regulator of carbon and energy metabolism and probably of other physiological pr

102 le analysis, which revealed that LBL favored energy metabolism and redirected metabolic pathways towa

103 Furthermore, genes involved in central and energy metabolism and ribosome biogenesis were dysregula

104 hat play a crucial role in the regulation of energy metabolism and systemic glucose homeostasis.

105 Independent validation of protein changes in energy metabolism and the antioxidant system was carried

106 ic modifications of genes involved in muscle energy metabolism and the long-term improvement of insul

107 n mature adipocytes significantly reprograms energy metabolism and this effect is primarily mediated

108 Similarly, Melainabacteria have diverse energy metabolisms and are capable of fermentation and a

109 s (GCs) are important regulators of systemic energy metabolism, and aberrant GC action is linked to m

110 tracellular matrix remodeling, mitochondrial energy metabolism, and apoptosis.

111 H(4) cycle), glycerophospholipid metabolism, energy metabolism, and aspartate metabolism.

112 ne synthesis, reproduction, immune function, energy metabolism, and cell signaling, which may contrib

113 a number of genes that promote angiogenesis, energy metabolism, and cell survival.

114 duction and role of saliva, blood digestion, energy metabolism, and development with submission of 10

115 obesity-associated WAT inflammation, improve energy metabolism, and increase thermogenic markers in B

116 ion rapidly increases hepatic lipid storage, energy metabolism, and insulin resistance.

117 thetic routes such as nucleotide metabolism, energy metabolism, and metabolism of amino acids.

118 re aberrantly reliant on cysteine to sustain energy metabolism, and that targeting this axis may repr

119 scribe a role for SF3B1 mutations in altered energy metabolism, and they offer a new therapeutic stra

120 as exercise place an unusual demand on liver energy metabolism, and this demand induces a state of en

121 ytoskeletal proteins and enzymes involved in energy metabolism are a prominent target of ROS.

122 itochondrial function, and deficits in brain energy metabolism are detected early in AD; however, dir

123 plementary measures of neurotransmission and energy metabolism are in partial agreement: BOLD and glu

124 Autophagy and energy metabolism are known to follow a circadian patter

125 generated substantial interest in inhibiting energy metabolism as a therapeutic paradigm.

126 ators of lymphoid transcription and cellular energy metabolism as drivers of venetoclax resistance in

127 eptor CAR (NR1I3) regulates hepatic drug and energy metabolism as well as cell fate.

128 eliciting regulatory effects on respiratory energy metabolism at night, uniting a hallmark mechanism

129 Energy metabolism, BC, and cardiorespiratory fitness may

130 ritical role in the regulation of whole-body energy metabolism because of its involvement in controll

131 pid (IHL) content, body composition, resting energy metabolism, blood pressure, plasma markers, physi

132 They not only play an important role in energy metabolism but also take part in many critical cy

133 on bifurcation plays a key role in anaerobic energy metabolism, but it is a relatively new discovery,

134 istones have been shown to regulate cellular energy metabolism, but their role in white adipose tissu

135 ma coactivator 1-alpha (PGC1alpha) regulates energy metabolism by directly interacting with transcrip

136 mon, but also specific, alternative modes of energy metabolism by reducing the stress caused by energ

137 isms for maintaining mitochondrial oxidative energy metabolism by restoring long-chain acyl CoA throu

138 of positive selection in pathways related to energy metabolism, cardiovascular homoeostasis, and haem

139 ptional downregulation of pathways mediating energy metabolism, cell cycle, and B cell receptor signa

140 iad of vital biological functions, including energy metabolism, cell death regulation, and innate imm

141 The affected pathways included energy metabolism, cell signaling, and immune responses.

142 ferential regulation of proteins involved in energy metabolism, cell-cell interactions, and protein-p

143 their functions related to carbohydrate and energy metabolisms, cellular components, and transport p

144 erlin deficiency leads to a reprogramming of energy metabolism characterized by a peroxynitrite-depen

145 cture in humans to address whether disrupted energy metabolism contributes to inflammation-induced be

146 owth, i.e., increasing protein allocation to energy metabolism, decreasing ATP demand, or increasing

147 xtent to which normal and pathophysiological energy metabolism depend on the GC receptor (GR) in adip

148 effects were concomitant with changes in the energy metabolism, detected as a relative increase of gl

149 cteristics of the human circadian system and energy metabolism differ between males and females, litt

150 ctively, the data suggest that disruption of energy metabolism drives behavioral and cognitive conseq

151 Disrupted energy metabolism drives cell dysfunction and disease, b

152 vealed that the deletion of ALX dysregulated energy metabolism driving toward age-related obesity.

153 g on proteomic-based analysis of the hepatic energy metabolism during developmental organ programming

154 rbation of adipocyte mitochondria influences energy metabolism during obesity.

155 P1-P761L variant leads to PDH deficiency and energy metabolism dysfunction, which promotes severe neu

156 e results suggest that relationships between energy metabolism, eosinophils, and IL-16 content are no

157 eases in genes associated with mitochondrial energy metabolism, fatty acid beta-oxidation, and mitoch

158 With this concept, we modeled energy metabolism for Escherichia coli and Saccharomyces

159 is: IF enhances mitochondrial biogenesis and energy metabolism gene expression in hippocampus, re-str

160 cant impact on our understanding of parasite energy metabolism given that Cryptosporidium lacks oxida

161 etformin-induced impairment of mitochondrial energy metabolism (glucose oxidation, O2 consumption, an

162 monitoring of changes in cytotoxicity (LDH), energy metabolism (glucose), and liver function (total b

163 igs was associated with a marked increase in energy metabolism (glycolysis and mitochondrial respirat

164 effect pathways, which may shed light on how energy metabolism has been hijacked to encourage tumour

165 Energy metabolism has been repeatedly linked to amyotrop

166 Energy metabolism has recently gained interest as a targ

167 , the role of the Sirt5 in regulating kidney energy metabolism has yet to be determined.

168 X receptor (FXR), a key regulator of hepatic energy metabolism, has potential for treatment of obesit

169 knockout cells displayed severely disturbed energy metabolism hindering induction of Warburg phenoty

170 lator at the molecular level for maintaining energy metabolism homeostasis.

171 ll receptor activation-induced remodeling of energy metabolism, however the underlying mechanisms rem

172 arnitines and amino acids are key players in energy metabolism; however, analytical methods for compr

173 4, harboring candidate genes associated with energy metabolism (IGFBP2, IGFBP5, SHOX, SMARCAL1, LYN,

174 vide evidence that HPV targets the host cell energy metabolism important for viral life cycle and HPV

175 is therapeutic strategy may alter myocardial energy metabolism in a manner that reverses the deleteri

176 eal-time monitoring of aerobic and anaerobic energy metabolism in bovine embryos, with potential appl

177 roteomics to characterize central carbon and energy metabolism in Candidatus Thioglobus singularis st

178 preciated role for HSF1 in the regulation of energy metabolism in fat tissues; however, whether HSF1

179 elucidate changes in biochemical pathways of energy metabolism in flight muscle relative to low-altit

180 eveals increased ATP production and improved energy metabolism in injured kidneys from mPGC-1alpha mi

181 further highlighting the role of calcium and energy metabolism in its toxicity.

182 It is unknown whether lactate contributes to energy metabolism in living tumors.

183 To gain insight into the function of CL in energy metabolism in mammalian cells, here we analyzed t

184 Oxygen is vital for energy metabolism in mammals and the variability of the

185 d seasonal rhythms, being a key regulator of energy metabolism in many animal species.

186 GPRC6A is proposed to regulate energy metabolism in mice, but in humans a KGKY polymorp

187 ction polymorphism that positively regulates energy metabolism in mice.

188 e cytosol and that pioglitazone may regulate energy metabolism in mitochondria by inhibiting the elec

189 s play an important role in regulating basic energy metabolism in normal cells, and that this functio

190 insulin sensitivity or related substrate and energy metabolism in overweight or obese prediabetic men

191 ake via MCU influences phototransduction and energy metabolism in photoreceptors using a mcu(-/-) zeb

192 metabolites through lipid, antioxidation and energy metabolism in response to inflammatory stimuli.

193 The peptide hormone adropin regulates energy metabolism in skeletal muscle and plays important

194 ional and experimental approaches to compare energy metabolism in the causative agent of sleeping sic

195 rgement in AQP3 deficiency involves impaired energy metabolism in the kidney through AMPK and mTOR si

196 f a peroxynitrite-dependent reprogramming of energy metabolism in tumor cells.

197 ly targets the altered form of mitochondrial energy metabolism in tumour cells, causing changes in mi

198 oxidative phosphorylation and mitochondrial energy metabolism in vitiligo.

199 copy (MRS), the modality of choice to assess energy metabolism in vivo.

200 hanisms, we determined the effects of VPA on energy metabolism in yeast.

201 protein kinase (AMPK), a master regulator of energy metabolism, in response to ZIKV challenge.

202 ory activation, neuroendocrine regulators of energy metabolism including leptin and insulin, and micr

203 tedly, we found that the central pathways of energy metabolism, including glycolysis, the tricarboxyl

204 a metabolites altered by LPS are involved in energy metabolism, including lipoproteins, glucose, crea

205 presenting central pathways of mitochondrial energy metabolism, including the respiratory chain and e

206 ces reduced peel damage, while inhibitors of energy metabolism increased it.

207 Reduced activation of energy metabolism increases adiposity in humans and othe

208 underscore the significance of mitochondrial energy metabolism-independent signals in GIIS regulation

209 tes the effects of circadian misalignment on energy metabolism, indicating possible sex-specific mech

210 , support invasion and metastasis, reprogram energy metabolism, induce genomic instability and inflam

211 thesis, interference with DNA synthesis, and energy metabolism inhibition.

212 TP that was dissipated by co-incubation with energy metabolism inhibitors.

213 e propose a modeling concept that decomposes energy metabolism into biomass formation and ATP-produci

214 Insulin resistance and altered energy metabolism is common in non-alcoholic fatty liver

215 pported by the findings that protein mass of energy metabolism is conserved across conditions based o

216 For excess DA levels, a failure in energy metabolism is indicated.

217 Energy metabolism is measured by powerful and sensitive

218 ary and molecular mechanisms able to improve energy metabolism is of paramount medical importance bec

219 abtree effect in S. cerevisiae, meaning that energy metabolism is sufficient to explain the metabolic

220 The basic strategy of the methanogenic energy metabolism is to covalently bind C(1) species to

221 aling contributes to aging and cancer at the energy metabolism level.

222 cells impact cell structure, signaling, and energy metabolism, making lipid metabolism a potential d

223 Profiling postpartum energy metabolism may assist in optimizing weight manage

224 hese observations suggest that inhibition of energy metabolism may be a potential strategy to selecti

225 hypothesis that derailments of mitochondrial energy metabolism may be causative to chronic kidney dis

226 on this important pathway of fatty acid and energy metabolism may help understanding the role of red

227 However, it is unresolved whether energy metabolism may resultantly regulate major brain f

228 e T2DM was used to study heart mitochondrial energy metabolism, measuring bioenergetics and enzyme ac

229 (1) EVs are enriched in proteins related to energy metabolism, membrane modification, and reproducti

230 w therapeutic target for treating disordered energy metabolism metabolic syndrome and type 2 diabetes

231 o cellular adaptations of protein synthesis, energy metabolism, mitochondrial respiration, lipid and

232 e advantage of exercise, improving patient's energy metabolism, mobility, and quality of life.

233 sitivity and a higher expression of genes in energy metabolism, myogenesis, contractile properties an

234 Body-wide changes in bioenergetics, i.e., energy metabolism, occur in normal aging and disturbed b

235 e of GRE superfamily enzymes and enables the energy metabolism of B. wadsworthia This GRE is widely d

236 nal bioavailability of oxygen by driving the energy metabolism of colonic epithelial cells (colonocyt

237 S did not affect glycolytic or mitochondrial energy metabolism of human MNs in vitro.

238 Recent studies have shown that energy metabolism of monocytes is crucial in determining

239 quired devastating disorders that affect the energy metabolism of the body.

240 (TBI) is known to cause perturbations in the energy metabolism of the brain, but current tests of met

241 zidine is an antianginal agent that improves energy metabolism of the ischaemic myocardium and might

242 s, with indications of strain in the fat and energy metabolisms of both.

243 tulated to have operated as an early form of energy metabolism on primordial Earth.

244 supports a negative impact of dysfunctional energy metabolism on the disease progression in amyotrop

245 re also strongly correlated with the type of energy metabolism operating in the host.

246 This may result from altered energy metabolism or dietary habits.

247 l regulator of glucose tolerance, whole-body energy metabolism, or mitochondrial quality control.

248 olled fundamental cellular processes such as energy metabolism, organelle biogenesis and stress respo

249 rall levels of amino acids contribute to LSC energy metabolism, our current findings suggest that cys

250 Energy metabolism, oxidative stress, and sleep-three pro

251 oreography of biological processes involving energy metabolism, oxidative stress, inflammation, tissu

252 that it may be a useful probe for examining energy metabolism, particularly in BRAF-mutant melanoma,

253 In heart failure (HF), energy metabolism pathway in cardiac muscle changes from

254 that these gold nanocrystals act via a novel energy metabolism pathway involving the enhancement of k

255 between the drug metabolism pathway and the energy metabolism pathway, but little is known about thi

256 grains and added sugars on inflammation and energy metabolism pathways.

257 nd in IHL, body composition, blood pressure, energy metabolism, physical performance, or quality of l

258 bility to partake in phosphate, calcium, and energy metabolism, polyP recently gained a new functiona

259 The observation that a mutation linked to energy metabolism precipitates a pattern of neurodegener

260 nutrient environment profoundly affects cell energy metabolism, proliferation, and biosynthesis.

261 we found that OV-induced changes in central energy metabolism, pyruvate metabolism, and oxidative st

262 ism and physiology in terms of mitochondrial energy metabolism, reactive oxygen species production, g

263 How central energy metabolism regulates bacterial cell cycle functio

264 Analogous to the dual-functional key energy metabolism regulator, phosphofructokinase 2, Vip1

265 In late mouse pregnancy, rhythmicity of energy metabolism-related genes in the muscle followed t

266 ned by a systems-wide shift in expression of energy metabolism-related genes.

267 functions of FGF19 in bile acid, glucose and energy metabolism remain intact.

268 However, the role of miR-31-5p in energy metabolism remains elusive.

269 equired for the proper control of whole-body energy metabolism, remains challenging.

270 Cellular-resolution imaging of energy metabolism reveals a concurrent elevation of ener

271 With regards to energy metabolism, striking spatial gradients have recen

272 tal when monocarboxylic acid products of the energy metabolism, such as l-lactate, are released from

273 insulin resistance-related abnormalities of energy metabolism, such as lower total respiratory excha

274 s and experimental data were associated with energy metabolism, terpenoid biosynthesis, fatty acids,

275 alterations in translational regulation and energy metabolism that characterize these patients.

276 Mitochondria are major sites of energy metabolism that influence numerous cellular event

277 They also induced shifts in energy metabolism that led to the production of the inte

278 protein kinase (AMPK) is a key regulator of energy metabolism that phosphorylates a wide range of pr

279 These alterations indicate improved energy metabolism through increased beta-oxidation of fa

280 to characterize the response of the liver's energy metabolism to a controlled perturbation in diet.

281 Modulation of energy metabolism to a highly glycolytic phenotype, i.e.

282 er analysis indicated alteration in cellular energy metabolism to be associated with S. haematobium i

283 yl-CoA carboxylase 1 (Acc1) connects central energy metabolism to lipid biosynthesis and is rate-limi

284 llular TG accumulation, and to alter hepatic energy metabolism to support complete oxidation of FA an

285 loss of function leads to reduced control of energy metabolism, ultimately impacting mitochondrial me

286 alterations in mitochondrial physiology and energy metabolism under resting conditions.

287 alysis indicated that alteration in cellular energy metabolism was associated with S haematobium infe

288 The overall energy metabolism was found to be strikingly robust, and

289 oughout the day/night cycle, suggesting that energy metabolism was regulated through adjustments in m

290 ase by having a direct effect on immune cell energy metabolism was tested using extracellular flux an

291 with statistical modelling and modulation of energy metabolism, we demonstrate a functional role for

292 investigate the potential roles of Gpr27 in energy metabolism, we generated a whole body gpr27 knock

293 evance of PHOPSPHO1 in BAT thermogenesis and energy metabolism, we show that PHOSPHO1 knockout mice a

294 xygen species (ROS) and toxic by-products of energy metabolism which can lead to cell death.

295 dentified four possible master regulators of energy metabolism, which all were generally upregulated

296 auses dysfunctional mitochondria and altered energy metabolism, which further leads to systemic oxida

297 lizer valproate (VPA) causes perturbation of energy metabolism, which is implicated in both the thera

298 estion in this context is how cells organize energy metabolism, which is, however, challenging to elu

299 ubs, indicating that POP exposure alters the energy metabolism, which, in turn, may be linked to meta

300 ion as a moonlighting enzyme to link central energy metabolism with S-phase entry.