ライフサイエンスコーパス: engender

1 regulation and also the models those results engender.

2 or correcting the social ills that prejudice engenders.

3 rted a poorly protective vaccine to one that engenders 100% protection.

4 terial flagellin, a TLR5 ligand (TLR5L), can engender a costimulatory signal that augments antitumor

5 mutations in TMs 6 and 7 that, when mutated, engender a mode switch in the pharmacology of certain PA

6 Altogether, our results engender a molecular understanding of the identified abe

7 classic chemotherapy that debulks tumors may engender a more effective strategy to achieve durable re

8 HSC and promotes myeloid differentiation to engender a myeloproliferative phenotype.

9 lones can be donor-derived and in some cases engender a new myeloid neoplasm that is clonally unrelat

10 -independent signaling pathways in ways that engender a new therapeutic strategy to attack breast can

11 opted murine intra-abdominal sepsis model to engender a phenotype that conforms to current sepsis def

12 se results suggest that action sequences can engender a prolonged mode of dopamine signaling in the n

13 Biased G protein-coupled receptor agonists engender a restricted repertoire of downstream events fr

14 nderstanding of the characteristics that can engender a small molecule with the ability to function a

15 astrocytes and microglia, among others - can engender a state of chronic cellular senescence that is

16 collaboration between three laboratories has engendered a design for synthesis featuring two sequenti

17 Unexpectedly, gradual loss of HDAC-activity engendered a dosage-dependent accumulation of immature t

18 Next generation sequencing technologies have engendered a genome sequence data deluge in public datab

19 st in fuel cell vehicle technology (FCV) has engendered a growing need and realization to develop rat

20 Thus, the Butantan-DV vaccine engendered a mature, antigen-selected B cell repertoire.

21 ncation or mutation of the N terminus of A17 engendered a phenotype consistent with the N terminus of

22 r immune microenvironment, which in turn has engendered a pressing need for robust experimental syste

23 e pathways revealed that IS and PCS exposure engendered a prodiabetic state evidenced by elevated res

24 gnaling compounds during the last decade has engendered a renewed interest in the chemistry of these

25 zole, but a para-chloro or bromo substituent engendered a second closed conformation.

26 utcompete G3BP auto-inhibitory interactions, engendering a conformational transition that facilitates

27 This engenders a better understanding of the fitness conseque

28 However, this trend engenders a challenge of optimal experimental design: du

29 se a model wherein the 4E-T/4EHP interaction engenders a closed-loop mRNA conformation that blocks tr

30 th triphenyltin radical in refluxing toluene engenders a contact ion-pair (radical cation) that leads

31 terozygous mutation of the Cxcr4 gene, which engenders a desensitization-resistant receptor.

32 Each analyte enantiomer engenders a diastereomer with distinct fluorescence wave

33 The ligand-based reduction engenders a dramatic modulation of the physical properti

34 eveloping a retirement plan eases stress and engenders a feeling of confidence about the future.

35 Conflict engenders a host of untoward consequences for patients,

36 CpG activation engenders a metabolic state that requires fatty acid oxi

37 A disease-causing mutation in human STN1 engenders a selective defect in POLA2-binding and PP sti

38 The library engenders a structured approach to tier and interrelate

39 a phosphorus center in the lower half, which engenders a unique element of axial chirality.

40 Phenylpropanoid biosynthesis in plants engenders a vast variety of aromatic metabolites critica

41 These advances have influenced, and even engendered, a phenomenal array of bioscience fields, inc

42 , but in situations with changing demands it engenders accuracy by delaying responses.

43 salience of (external or internal) cues that engender action.

44 Reconciling these observations is engendering active debate about the physical state, spat

45 apable of efficient parenteral transmission, engendering acute and chronic infections associated with

46 ldhood(18), we found little evidence that it engenders additional benefits to executive function deve

47 elevated plasma levels are not sufficient to engender albuminuria.

48 ity of single cells in regulative embryos to engender all somatic and germline cell types.

49 the remarkable capacity of a single cell to engender all the specialized cell types of an adult orga

50 ustification and American Dream ideology, in engendering Americans' relative insensitivity to economi

51 Films thicker than 2 A engender an exponential decrease in ET time with increas

52 minate tumors is limited by their ability to engender an immunosuppressive microenvironment.

53 egraded/jittered up-stream acoustic code may engender an increased preference for predictable/repeati

54 The N-hexyl groups engender an XB-induced polymeric pseudocapsule and an XB

55 Type I interferon (IFN) signaling engenders an antiviral state that likely plays an import

56 silica particles modified with amine linkers engenders an effective heterogeneous SABRE (HET-SABRE) c

57 sm, pharmacological heart rate lowering also engenders an increase in central (aortic) BP in coronary

58 Concurrently, stopped light engenders an inherent and cavity-free feedback mechanism

59 imitation illuminates how the initial state engenders and supports rapid social learning.

60 une system in a manner that is sufficient to engender antitumor responses.

61 s in which yeast cell invasion of lung MPhis engenders apoptosis, triggered in part in an autocrine T

62 er of two cell populations was sufficient to engender ASDs but that expression solely in either one o

63 mistranslation specifically with methionine engendered at the tRNA charging level occurs in mammalia

64 ls of DNA, due to the additional overhang it engenders at the junction.

65 n inhibitory-cell-specific role of 4E-BP2 in engendering autism-related behaviors.

66 xcitatory and inhibitory synaptic functions, engendering autistic-like behaviors.

67 s in both adult mice and their offspring and engendered behavioral alterations.

68 The precise mechanisms by which DR engenders benefits on processes related to learning rema

69 erocycle with a secondary binding pocket may engender bias.

70 ivity which may prevent overdose issues, and engendering bias by differentially modulating distinct s

71 sitive allosteric modulator--specifically to engender biased signaling at the A1AR.

72 Both isoforms engender biased signaling, notably for 4-[3-(benzyloxy)p

73 ary adducts form in the presence of acid and engender both electrophilic isocyanate activation and nu

74 t as it matures, revealing that the reaction engenders both MBC subsets with different immune effecto

75 thesized that this reward-timing activity is engendered by a reinforcement signal conveying reward ac

76 Codon bias engendered by an A + T rich genome may influence how pos

77 ECM fibrils throughout the eye thought to be engendered by an increased oxidative stress state.

78 The biased signaling engendered by BETP suggests that GLP-1 receptor mobiliza

79 wpl1 also fails to suppress cohesion defects engendered by blocking just the essential Eco1p acetylat

80 play a key role in the etiology of diseases engendered by chronic pollutant exposure.

81 d are driven by decreases in trustworthiness engendered by decisions to hide (experiments 3A and 3B).

82 ) and dehydrobutyrine (Dhb), two amino acids engendered by dehydration of serines and threonines, res

83 The massive socioeconomic impacts engendered by extreme floods provides a clear motivation

84 dies that illustrate how the immune response engendered by helminth parasites modulates Mtb-specific

85 NX nearly eliminated impulsive action in DRL engendered by hunger, at a dose (1 mug) that significant

86 mprovements in antiangiogenic therapy can be engendered by metronomic dosing.

87 ce is a common factor; systemic inflammation engendered by obesity may be another.

88 ible for most, if not all, of the protection engendered by OMV vaccination, thus providing insight in

89 major cause of child mortality in Africa, is engendered by Plasmodium parasites that are transmitted

90 Yet, the neuroanatomical differences engendered by population history are still poorly unders

91 el that captures fluctuations in self-esteem engendered by prediction errors that quantify the differ

92 NA filaments may explain some of the defects engendered by RECQ helicase deficiencies in human cells.

93 cardiomyocytes both result from bifurcations engendered by stimulation that modifies the stability of

94 h without increasing the noise and confusion engendered by the collection of data against a range of

95 major perturbations that would otherwise be engendered by the greatly increased intracellular glucos

96 he coupling is attributed to the steric bias engendered by the mesityl acetal of 87 and contact ion p

97 EF significantly reduced the behavioral cost engendered by the salient distractor relative to left FE

98 p2 has ATP binding and hydrolysis activities engendered by the Walker A and B motifs respectively.

99 The decrease in the thermodynamic barrier engendered by this coupling also enables homogeneous CO(

100 is a testament to the early success and hope engendered by this line of investigation.

101 letion of Nkx2.5 whereas mesodermal deletion engendered cardiac defects almost identical to those obs

102 y be most effective under contingencies that engender choice of relatively low cocaine doses.

103 osely associated with the gut epithelium and engendered cognate Th17 cells without attendant inflamma

104 Thus, the oxytocinergic system, potentially engendering cohesion and cooperation when facing an out-

105 This discrepancy has engendered concerns about large evolutionary shifts in m

106 These features have engendered considerable interest in generating distinct

107 euron's signal pathway appears sufficient to engender context-sensitive cortical adaptation.

108 Taken together, these data have engendered controversy regarding the specific role of TG

109 t of the TGF-beta receptor or SMAD3, thereby engendering controversy regarding the mechanism of disea

110 itors might be a generalizable technique for engendering convenient loss-of-function reagents with gr

111 o avoid the trap of parochialism and instead engender cooperative behavior with the broader global co

112 Infection with lab and clinical strains engendered cytotoxic amyloids that were capable of being

113 ard hydrogen bonding and ability to reliably engender defined conformations in drug ligands.

114 As these alterations have been shown to engender dependence on the oncogenic protein Skp2 for su

115 under) in which stimuli are encountered can engender different behavioral responses to the same stim

116 PM) to the amphipathic glycoside saponin and engenders digestive vacuoles (DVs) that are small and ma

117 rders propose that hypoactivity in the vmPFC engenders disinhibited activity of the amygdala and, con

118 This network perturbation engenders disorganized, impulsive appetitive responses.

119 different sets of sites within GHSR1a which engender distinct functionality of ss-arrestins.

120 The carbon-fluorine bond engenders distinctive physicochemical properties and sig

121 site 180 is a sufficient activator alone and engenders dominant mono-phosphorylation activity.

122 nomeline increased time awake in rodents and engendered dose-limiting adverse effects in NHPs.

123 the capacity of A192PP to colonize the gut, engender double-strand breaks in DNA, and cause invasive

124 e compensatory signaling mechanisms that can engender drug resistance to individual targeted drugs.

125 nt smallpox and the population-wide immunity engendered during eradication efforts, could monkeypox n

126 ans of defending spirochetes against threats engendered during the blood meal.

127 investment in new biological characters that engender ecological adaptability.

128 ponds under differing attentional demands to engender effective behavior.

129 Engendering electrical conductivity in otherwise insulat

130 Moreover, a general approach to engender endogenous patient-specific cellular therapy, w

131 In the vasculature, p66Shc-induced ROS engenders endothelial dysfunction.

132 The formal recycling process can, however, engender environmental impact and resource consumption,

133 Polymyxin B addition engendered Escherichia coli and Pseudomonas aeruginosa G

134 Pain management in opioid abusers engenders ethical and practical difficulties for clinici

135 e ease with which genome multiplications can engender evolutionary innovation.

136 ability of low-coordinate metal fragments to engender extremely strong magnetic exchange coupling thr

137 the radiotracer, as well as conditions that engender false-positive results.

138 ts the use of uncertainty representations to engender fast, adaptive responses.

139 on of whether an RBF(3)K reagent will likely engender "fast", "slow", or "very slow" hydrolysis.

140 ss proposes that the anterior insular cortex engenders feelings that provide an amodal valuation of h

141 of an electrode surface (i.e., double layer) engender fluid flow within a serpentine channel containi

142 However, plant tissue culture is known to engender frequent unwanted variation, termed somaclonal

143 It also engenders fresh views on the assembly of the microbiome,

144 alytically impaired LEOPARD syndrome mutants engender gain-of-function phenotypes?

145 ion in comparison to APIc at pH 7.0 and also engendered gelation at pH 4.0 and 9.0 contrary to APIc.

146 ave physiological meaning, make it ideal for engendering generalizable mechanistic insight and should

147 ding those in VHL, SET2, PBRM1 and BAP1, may engender genomic instability and promote defects in DNA

148 This discovery has engendered great hope that it could prove clinically imp

149 ively faster growth speed could consistently engender gyri.

150 ries shows strong, overly precise priors can engender hallucinations in healthy subjects and that ind

151 (RM) CMV vaccine vectors expressing HBV Ags engender HBV-specific CD8(+) T cells unconventionally re

152 er the role of the tumor microenvironment in engendering heterogeneity and drug resistance.

153 an-to-mouse low-affinity FcgammaR locus swap engendered hFcgammaRIIA/IIB/IIIA/IIIB expression in mice

154 Conversely, intra-PFC DAMGO engendered 'high-drive-like' effects: enhancement of PR

155 ations and the feelings that such violations engender; however, a computational rendering of the unde

156 anisms by which altered telomere maintenance engenders human disease.

157 Palatable feeding engenders hypersensitivity of Acb shell GABA responses;

158 onding melting point of the solidified PSLs, engendering ice and frost repellency even on hydrophilic

159 ether, our data demonstrate that liver stage-engendered IFN-1 signaling impairs hepatic CD8 T cell me

160 * manifold, contrasting previous methods for engendering iminyl character through chemical oxidation.

161 more than listening preferences alone: they engender in infants a heightened focus on the objects in

162 The metabolic cost engendered in sustaining interneuronal communications ha

163 against reactive oxygen and nitrogen species engendered in the context of a functional NRAMP1(R) diva

164 Thus, cocaine dependence seems to engender increased responsiveness to unexpected negative

165 ars to be a critical biophysical feature for engendering inherent acute synaptotoxicity, with preform

166 Obesity-induced inflammation engenders insulin resistance and type 2 diabetes mellitu

167 and the highly virulent SchuS4 strain of Ft engenders intense peribronchiolar and perivascular infla

168 First, we investigated the traits that engender interest in a scientist's work, and those that

169 This complexity has engendered interest in agonists that preferentially stim

170 Recent advances in neuroscience have engendered interest in large-scale brain networks.

171 This engenders interest in evaluating thalidomide analogues s

172 Full synaptic recovery engendered interictal population spikes that spread via

173 Advances in stem cell technology have engendered keen interest in cell-based therapies for neu

174 on super- and double exchange mechanisms to engender large spin ground states.

175 Biot coefficient, must cause the fracking to engender lateral branching and the opening of hydraulic

176 Acceptable levels of risk theme demonstrated engendered leadership beliefs, that is, when clinical ju

177 r CD16 as a bifunctional receptor capable of engendering long-lasting NK cell inhibitory signals.

178 tended conjugation along one molecular axis, engendering low optical bandgaps and improved oscillator

179 le insights as to how the actin cytoskeleton engenders mechanoresponsiveness of living cells.

180 Potent active-site mTOR inhibitors engender mitochondrial hyperfusion due to the diminished

181 miltonians, exhibit a transition which could engender modes that exponentially decay or grow with tim

182 s of diagnosis or the treatment of a disease engendered more controversy than gastroesophageal reflux

183 We conclude that tumor-derived OPN engenders MSC-to-CAF transformation in the microenvironm

184 When combined, however, they engender much higher inhibition of PI3K signaling and st

185 o many classes of antibiotics vertically, by engendering mutations in genes encoding transcriptional

186 complete an emergency myelopoietic response, engendering myeloid cells that fail to clear secondary i

187 , the pathways by which sarcomeric mutations engender myocyte hypertrophy and electrophysiological ab

188 reptiles have non-occluding dentitions that engender negligible bone damage during feeding.

189 SVs), most of which are catalytic nulls that engender new biology.

190 ic divisions and to divide asymmetrically to engender new cells that can progress to differentiate in

191 We tested the hypothesis that AT-rich DNA engenders NFR formation by virtue of its rigidity and co

192 accompanied by decreases in GSNOR activity, engendering nitrosative stress.

193 ked to urges to move the body, putatively by engendering noisier sensory input into motor decision pr

194 mechanisms between these two disorders will engender novel hypotheses in future preclinical and clin

195 nclear cell variants of RCC are beginning to engender novel therapeutic strategies directed against t

196 ppended domain like other human aaRSs, which engendered novel functions, a new AlaRS architecture was

197 y resistant to feedback control, which could engender obesity through the enhancement of palatable fe

198 mice developing SMZL and contributes to the engendering of detrimental proinflammatory conditions.

199 ., the degree of emotionality that a symptom engenders) of symptoms among patients and proxy reporter

200 Combination of anti-CTLA4 and anti-PD1 engendered only modest efficacy.

201 framework to show how high-dose chemotherapy engenders opposing evolutionary processes involving the

202 ersity of novel strategies under development engenders optimism that a successful candidate will emer

203 BACE1 deficiency also engenders organization defects in the postsynaptic compa

204 Furthermore, although the two hosts engender ostensibly identical encapsulation environments

205 o investigate changes in stress distribution engendered over the colon tissue by the presence of a po

206 ray of proteins and biological pathways that engender PAR1 biased signaling in endothelial cells.

207 activation of the innate immune response can engender pathological inflammation and autoimmune diseas

208 timing behavior, in part, by augmenting time-engendered patterns of dopamine release.

209 sical attributes of the three isoforms might engender payoffs under specific conditions.

210 t highly complex and interconnected networks engender perceptual awareness.

211 Traumatic events can engender persistent excessive fear responses to trauma r

212 data strongly suggest that over-hunting has engendered pervasive changes in tree population spatial

213 etry by the creation of polar domains, which engender polarization and pyroelectricity in the doped c

214 Although low connectivity should engender population resilience to shifts in habitat (e.g

215 act symmetrical shapes or random pattern can engender positive or negative affect as long as the regu

216 f presentation of novel symmetrical patterns engenders positive affect using a priming paradigm.

217 observations indicate that sleep curtailment engenders positive energy balance via increased palatabl

218 ties of a different class ( e.g., IgE) could engender potent effector cell activation, and unleash pr

219 upport the notion that cationic NP platforms engender potent humoral and mucosal immune responses.

220 ghlighted the PbGH5A active-site motifs that engender predominant mixed-linkage endo-glucanase activi

221 However, language switches did not always engender processing difficulties: the switch cost was re

222 killing and the host immunologic response it engenders produce potent, lasting antineoplastic effects

223 tegy for retaining GLP-1-like activity while engendering prolonged activity in vivo, based on strateg

224 le Haemophilus influenzae and S. pneumoniae, engendering protection against acute otitis media caused

225 habditis elegans enhanced RAS signalling and engendered protruding vulva, a phenotype previously link

226 These cells engendered rapid, isotype-switched secondary plasmablast

227 assembly and catalyst encapsulation further engenders reaction selectivity, which reaches an even gr

228 urther, the presence of Wolbachia itself may engender reproductive isolation, and promote speciation

229 The high cost of critical care has engendered research into identifying influential factors

230 rmacophore that is exploited by the virus to engender resistance and provide a structural framework f

231 fective in cancer patients nearly invariably engender resistance at some stage, an inherent challenge

232 ings identify a mechanism by which VISTA may engender resistance to anti-tumour immune responses, as

233 ve therapies in that they are less likely to engender resistance, will likely have efficacy against a

234 candidate proteins that could be pivotal in engendering resistance and implicates chloroplasts as th

235 (+)-EPI and the partial agonist varenicline engendered, respectively, complete and partial substitut

236 s with alkoxy or benzyloxy (OR) substituents engenders reversible redox chemistry, providing access t

237 tions (A389V, V485I, E527Q, Q549R and Q733D) engender RNA deaminase in human ADAR3.

238 dent model of chronic early-life stress that engenders robust and enduring increases in anxiety-like

239 We conclude that this saturation engenders robustness of the localization process in the

240 This reduced progenitor pool fitness engenders selection for cells harboring oncogenic mutati

241 lies, which have garnered many successes and engendered several long-standing controversies regarding

242 both pro- and anti-tumorigenic effects that engender significant challenges in the path towards pers

243 d by the m-terphenyl groups is also shown to engender significant stability towards heat as well as a

244 d functional level such that similar stimuli engender similar internal representations.

245 intained telomeres, whereas deletion of both engendered similar telomere loss, suggesting that the re

246 ithin a leukemic hematopoietic stem cell has engendered some controversy.

247 Pleiotropic signaling pathways must somehow engender specific cellular responses.

248 This network structure engenders specific network dynamics and imparts greater

249 These observations have engendered speculation that the seemingly flexible gamma

250 coupling into magneto-optic waveguide media engenders spin-helicity-dependent unidirectional propaga

251 AIL and NODAL mRNA isoforms akin to hypoxia, engendering stem-cell-like phenotypes.

252 We also found that BQCA engenders stimulus bias at the M(1) DREADD, having diffe

253 disrupts the crystallinity of M(2)CO(3) and engenders strong base reactivity at intermediate tempera

254 alls and destabilizes DNA replication forks, engendering structural chromosomal aberrations.

255 Winning a competition engenders subsequent unrelated unethical behavior.

256 nearly identical behaviour in magnitude, but engenders substantial difference in phase between transm

257 ogeneity in particle-to-particle composition engenders substantial overestimation in absorption by th

258 live, replication-competent whole parasites engenders superior immunity and protection when compared

259 The ability to maintain normal IOP engendered survival of retinal ganglion cells, whose los

260 B lymphocyte stimulator (BLyS) engenders survival and antibody secretion, whereas CD40

261 r repeated associative learning to shape and engender synesthetic experiences.

262 Our objective was to engender synthetic lethality to paclitaxel (PTX), the fr

263 NSyL engenders systematic description and communication of co

264 in susceptibility to the environment, which engenders systematic person-environment interactions in

265 in our dietary pattern, dietary Pi overload engenders systemic phosphotoxicity, including excessive

266 precedented S-oxygenation of homocysteine to engender the corresponding sulfenic acid species that fu

267 tive media of defined specific activity will engender the development of novel applications for organ

268 controlled characteristic dimensions, which engender the electrode with significantly improved cycla

269 ults suggest T cell-inducing vaccines do not engender the rapid evolution of IAV.

270 whether splice variants of the same receptor engender the same or differential biased signaling.

271 on of the alkaloid, and together, these data engender the structural revision of (-)-galipeine to (S)

272 ragmented after stable, interglacial climate engendered the spread of peatlands at the same time that

273 Research into biomaterials has engendered the use of bioartificial nerve conduits as an

274 ase, we suggest that an inherent plasticity, engendering the formation of alternative stable conforma

275 the activation of the small GTPase Rac1 and engendering the mesenchymal-mode movement in three-dimen

276 ogies reveals that the locked superstructure engenders the formation of hierarchical 1D materials whi

277 ved extent of peripheral damage reproducibly engenders the same level of pain across individuals.

278 and demonstrate that in-school programs can engender these changes.

279 However, prior work has always engendered these associations with innately rewarding st

280 f the Fe-BPh interactions in these complexes engender this reactivity.

281 ut little is known about the conditions that engender this signaling profile or how it develops with

282 sed, and this inhibition must be reversed to engender tissue effects; however, the mechanisms that me

283 s, or the downstream effector molecules they engender, to limit inflammation.

284 ccession, indicating that genomic redundancy engenders tolerance to high mutation density.

285 nd vector potentials locally and globally to engender topologically distinct ground states and, ultim

286 Overall, MED18 conveys distinct cues to engender transcription underpinning plant responses.

287 further showed that this perceptual training engendered transfer-of-benefit to an untrained working m

288 These intrathymic B cells engender Tregs.

289 ications harbored unbranched C4 units, which engendered tweezers that were approximately one order of

290 designing bivalent or bitopic molecules that engender unique pharmacological properties began with Po

291 etic cation content at the central PK layers engenders up to a 90% increase in potential ferromagneti

292 scribe their advantages and shortcomings for engendering useful genetic alterations, and consider fut

293 anisms that appear qualitatively similar can engender vastly different outcomes for diversity: Depend

294 As a consequence, these channels have engendered very high interest as future drug targets.

295 e adhesive interactions are most effectively engendered via binding of the endothelial lectin E-selec

296 rds display elements of unconscious (covert) engendered views.

297 stantiate risk across different life stages, engendering vulnerability to conditions that develop sho

298 ing highly symmetric Ni(2+) centers, thereby engendering weak zero-field splitting to enable EPR addr

299 AG did not overcome the interference in OPKA engendered when these were combined with antibody to eit

300 aterials designed for such processes must be engendered with an exceptionally high enthalpy of adsorp