ライフサイエンスコーパス: ensheathe

1 d that only about 20-30% of each synapse was ensheathed.

2 m the extracellular matrix to first sort and ensheathe a single axon and then myelinate it.

3 ses that emerge from the single trunk do not ensheathe a single terminal.

4 ing oligodendrocytes are generated and axons ensheathed according to a tightly regulated sequence of

5 Schwann cells then ensheathe and wrap axons, and establish polarized, subce

6 from NRG1 type III deficient mice are poorly ensheathed and fail to myelinate; lentiviral-mediated ex

7 y parameters, such as the number of synapses ensheathed and the strength of this ensheathment, we sho

8 al muscle is produced by the muscle cells it ensheathes and by nonmuscle cells located in the surroun

9 In contrast, the widespread ensheathing and astrocyte-like glia derive from specific

10 tex where neuronal cell bodies reside, while ensheathing and astrocyte-like glia enwrap and infiltrat

11 proteins, erbB2 and erbB3, are expressed on ensheathing and myelinating Schwann cells and rapidly ph

12 hese cells extend and align their processes, ensheathe, and ultimately myelinate axons.

13 disproportionately unmyelinated, aberrantly ensheathed, and hypomyelinated, with reduced conduction

14 precursors, and that most adult perineurial, ensheathing, and astrocyte-like glia are produced after

15 ons, activated microglia closely apposed and ensheathed apical dendrites, neurites, and neuronal peri

16 do not tile: each astrocyte participates in ensheathing approximately one-quarter of all of the axon

17 tatus information via paracrine signals from ensheathing astrocytes.

18 und the glomerular neuropil; glial processes ensheathe axon bundles in the nerve layer but likely con

19 d Na+ channels and ankyrinG form adjacent to ensheathed axonal segments even in the absence of a myel

20 Myelin is a multilayered membrane that ensheathes axonal fibers in the vertebrate nervous syste

21 peripheral nerve development, Schwann cells ensheathe axons and form myelin to enable rapid and effi

22 Specialized glia ensheathe axons and support their function and integrity

23 ) indicated that Schwann cells must begin to ensheathe axons before inducing Na+ channel clustering.

24 This mutant has oligodendrocyte-ensheathed axons but lacks compact myelin and normal axo

25 In the coculture, myelin specifically ensheathed axons but not dendrites of hippocampal neuron

26 Ensheathed axons express low levels whereas myelinated f

27 Oligodendrocytes that ensheathed axons expressed and selectively targeted prot

28 as 3 months after injury and their processes ensheathed axons near and distal to the lesion, colocali

29 Mutant oligodendrocytes also ensheathed axons normally and made a few wraps of compac

30 t propagation of action potentials along the ensheathed axons.

31 ematic occurrence has remained undetected in ensheathed axons.

32 yelin in layer 2/3 and a quarter in layer 4) ensheathes axons of inhibitory neurons, specifically of

33 Myelin ensheathes axons to allow rapid propagation of action po

34 hat OPCs were more capable of contacting and ensheathing axons than OLs.

35 tebrate midline glia play important roles in ensheathing axons that cross the midline and secreting s

36 o mature oligodendrocytes and are capable of ensheathing axons with myelin without molecular cues fro

37 Glia play crucial roles in ensheathing axons, a process that requires an intricate

38 a present on CSF-facing leptomeningeal cells ensheathing blood vessels in the subarachnoid space may

39 elaborate membrane extensions that partially ensheathed both commissures.

40 t regenerated into grafts, and appropriately ensheathed but did not myelinate sensory axons extending

41 Furthermore, axoplasm ensheathed by 65% of the CNS incisures examined by elect

42 of numerous short and swollen lateral roots ensheathed by a fungal mantle.

43 The Drosophila nervous system is ensheathed by a layer of outer glial cells, the perineur

44 elop the adult neuroblast and are themselves ensheathed by a layer of processes of multipolar cell bo

45 Along their route, neuroblasts are ensheathed by astrocyte-like cells expressing vesicular

46 a network of chains of migrating neuroblasts ensheathed by astrocytes and juxtaposed by clusters of i

47 the adult, migrating SVZa-derived cells are ensheathed by astrocytes, although the function of these

48 longated aggregates called chains, which are ensheathed by astrocytes.

49 these neuronal precursors migrate in chains, ensheathed by astrocytic processes, and travel toward th

50 t only those maturing blood vessels that are ensheathed by astroglial processes.

51 litated by fiber bundles, particularly those ensheathed by fibroblastic reticular cells in the lymph

52 cular network, a meshwork of collagen fibers ensheathed by fibroblastic reticular cells that connects

53 peripheral nerves are unmyelinated but still ensheathed by glia.

54 show that individual or a group of axons are ensheathed by inner glial processes, which in turn are e

55 Axons in the PNS and CNS are ensheathed by multiple layers of tightly compacted myeli

56 tial proportion of these APP+ spheroids were ensheathed by myelin, a finding that was confirmed in th

57 propagation of action potentials, axons are ensheathed by myelin, a multilayered insulating membrane

58 e primary heart tube is an endocardial tube, ensheathed by myocardial cells, that develops from bilat

59 and ankyrinG are adjacent to axonal segments ensheathed by oligodendrocytes, but at P21, many node-li

60 Axons ensheathed by oligodendroglial processes, but not yet my

61 he abluminal surfaces of CNS capillaries are ensheathed by pericytes and astrocytes.

62 ive (-IR) neurons have also been shown to be ensheathed by perineuronal nets (PNN), extracellular mat

63 (+) neuronal glutamatergic synapses that are ensheathed by processes from individual developing astro

64 In the retina, RGCs are ensheathed by retinal Muller glial (RMG) cell processes.

65 ckout mice develop normally, become properly ensheathed by Schwann cells, and appear to function norm

66 The CNS is ensheathed by the meninges and cerebrospinal fluid, and

67 by inner glial processes, which in turn are ensheathed by the outer perineurial glial cells.

68 mum of an astrocytic process, but none were ensheathed by those processes.

69 peripheral nerve in the Drosophila larva is ensheathed by three glial layers, which structurally sup

70 Chains of Type A cells were ensheathed by two ultrastructurally distinct astrocytes

71 +) tumor cells project cellular processes to ensheathe capillaries in mouse medulloblastoma (MB), a p

72 lved concurrently with brain vasculature and ensheathe capillaries throughout the brain.

73 The olfactory ensheathing cell (OEC) has attracted much interest recen

74 spinal cord transection model and olfactory ensheathing cell (OEC) or fibroblast (FB; control) trans

75 the fact that the neuroprotective olfactory ensheathing cell (OEC) subset is difficult to isolate, m

76 Olfactory ensheathing cell (OEC) transplantation is a candidate ce

77 One beneficial therapy, olfactory ensheathing cell (OEC) transplantation, results in funct

78 lfactory receptor neuron (ORN) and olfactory ensheathing cell maturation; however, directed outgrowth

79 ork has implicated this pathway in olfactory ensheathing cell support for regeneration of axons from

80 Intraspinal olfactory ensheathing cell transplantation improves locomotor outc

81 ently discovered type of cell, the olfactory ensheathing cell, which can be obtained from the adult n

82 After SCI, ensheathing cells (ECs) promote recovery in animal model

83 eeze fracture, P faces of both the axons and ensheathing cells (glia that surround the axon fascicles

84 ne or in combination with cultured olfactory ensheathing cells (OEC) into the lesion cavity 6 weeks a

85 st that correct development of the olfactory ensheathing cells (OEC) is imperative for normal GnRH-1

86 lantation of a mixture of 50% p75+ olfactory ensheathing cells (OECs) and fibroblasts derived from th

87 Olfactory ensheathing cells (OECs) are candidate cells for transpl

88 Olfactory ensheathing cells (OECs) are known to enhance axonal reg

89 Olfactory ensheathing cells (OECs) are often described as being pr

90 Olfactory ensheathing cells (OECs) are specialized glia associated

91 Olfactory ensheathing cells (OECs) are the glia of the primary olf

92 Olfactory ensheathing cells (OECs) are unique glial cells found in

93 Transplants of olfactory ensheathing cells (OECs) cultured from the olfactory bul

94 ss Fz-1, Fz-3, and Wnt-5a, whereas olfactory ensheathing cells (OECs) express Wnt-4.

95 Olfactory ensheathing cells (OECs) have been reported to migrate l

96 Olfactory ensheathing cells (OECs) have been shown to mediate remy

97 Olfactory ensheathing cells (OECs) have considerable potential for

98 Olfactory ensheathing cells (OECs) have neuro-restorative properti

99 's gland cells, and GFAP(+)/p75(-) olfactory ensheathing cells (OECs) in the underlying lamina propri

100 allei infection, we infected human olfactory ensheathing cells (OECs) in vitro and measured bacterial

101 Transplantation of olfactory ensheathing cells (OECs) into injured spinal cord result

102 ere we describe transplantation of olfactory ensheathing cells (OECs) or Schwann cells derived from t

103 Olfactory ensheathing cells (OECs) or Schwann cells were transplan

104 Olfactory ensheathing cells (OECs) prepared from the olfactory bul

105 n of the calcium influx pathway in olfactory ensheathing cells (OECs) was performed using Indo-1 calc

106 actory sensory neurons (OSNs), and olfactory ensheathing cells (OECs), but was excluded from mature O

107 t rat Schwann cells (SCs), but not olfactory ensheathing cells (OECs), form a boundary with astrocyte

108 L a population of glial cells, the olfactory ensheathing cells (OECs), surround OSN axon fascicles.

109 for three-dimensional culturing of olfactory ensheathing cells (OECs), which can be used to understan

110 Olfactory ensheathing cells (OECs), which have properties of both

111 es include Schwann cells (SCs) and olfactory ensheathing cells (OECs).

112 n (GFP)-expressing donor rats [GFP-olfactory ensheathing cells (OECs)] into a region of spinal cord d

113 s and IL-6 from infiltrating macrophages and ensheathing cells act as repair factors in the ON.

114 prove that the NC give rise to the olfactory ensheathing cells and subpopulations of GnRH-1 neurons,

115 Olfactory ensheathing cells are a type of glial cell which can be

116 on of expression of LIFR, IL-6, and IL-6R in ensheathing cells by 3 days post-OBX.

117 ovide evidence that these specialized vessel-ensheathing cells contribute to the S1P that promotes th

118 A suspension of ensheathing cells cultured from adult rat olfactory bulb

119 Here, we transplanted olfactory ensheathing cells from green fluorescent protein (GFP)-e

120 ared following transplants of pure olfactory ensheathing cells from neonatal animals and mixed olfact

121 The origin of GnRH-1 cells and olfactory ensheathing cells has been controversial.

122 cent discovery of the potential of olfactory ensheathing cells has proved a significant advance.

123 ss in a first application of human olfactory ensheathing cells in clinical brachial plexus injury wou

124 l nerve glia play roles similar to olfactory ensheathing cells in supporting axon elongation, yet dif

125 eronasal progenitors, formation of olfactory ensheathing cells in the nasal mucosa, and impairs GnRH-

126 erved in Gli3 mutants from lack of olfactory ensheathing cells in the nasal mucosa, moreover, we disc

127 ounding the olfactory epithelium (OE) and by ensheathing cells in the nerve layer of the ventral olfa

128 models transplantation of cultured olfactory ensheathing cells into an injured spinal cord induces re

129 a of olfactory mucosa and cultured olfactory ensheathing cells into the lesion cavity) 6 weeks after

130 Schwann cells are the nerve ensheathing cells of the peripheral nervous system.

131 ervations indicate that Sema3A expression by ensheathing cells plays an important role in guiding olf

132 Ensheathing cells remained restricted to the outer nerve

133 transplantation of cultured adult olfactory ensheathing cells restores the sensory input needed for

134 demonstrate that Schwann cells and olfactory ensheathing cells share a common developmental origin.

135 How perineurial glia, the ensheathing cells that form the protective blood-nerve b

136 ultures (containing a mean of ~50% olfactory ensheathing cells) in a population of spinal cord-injure

137 s, elevation of cyclic AMP levels, olfactory ensheathing cells, a steroid or chondroitinase.

138 they share features with mammalian olfactory ensheathing cells, the developmental roles of antennal n

139 roots and differentiate into nonmyelinating ensheathing cells.

140 ialized extracellular matrix structures that ensheathe certain neurons during development over the cr

141 Within lymph nodes, stromal cell-ensheathed conduit networks transport small antigens dee

142 e showed that activated microglia physically ensheathe cortical projection neurons, which have reduce

143 Chromosome ensheathing delays mitosis and increases the frequency o

144 In many instances, CARTir terminals ensheathed dendrites of SNr neurons.

145 e most efficient mixtures were aggregates of ensheathed DNA and fused liposomes.

146 ry endings accommodated in a lumen formed by ensheathing epithelia or glia.

147 tures-the choroid plexus vasculature and its ensheathing epithelium.

148 These arterioles are ensheathed exclusively by rare NG2 (also known as CSPG4)

149 ed can direct midline glia to a PMG-like non-ensheathing fate.

150 ndicate that NG exchanges identities between ensheathing glia (EG) and astrocyte-like glia (ALG).

151 everal studies have suggested that olfactory ensheathing glia (EG) can form Schwann cell (SC)-like my

152 promoting properties of adult olfactory bulb ensheathing glia (EG).

153 Olfactory ensheathing glia (OEG) are distinct from other glia in t

154 promise are olfactory bulb-derived olfactory ensheathing glia (OEG) transplantation and treadmill ste

155 As olfactory ensheathing glia (OEG) transplantation improves hindlimb

156 n anatomical evidence suggest that olfactory ensheathing glia (OEG) transplantation promotes axon reg

157 d adult rat Schwann cells (SCs) or olfactory ensheathing glia (OEG), or both, were transplanted in th

158 ormal locomotion which is similarly shown by ensheathing glia ablated larvae.

159 ll types in the adult Drosophila brain, with ensheathing glia acting as phagocytes after axotomy, and

160 Together these results argue that ensheathing glia and astrocytes are preprogrammed cell t

161 s contain two different populations of glia: ensheathing glia and astrocytes.

162 We find that ensheathing glia are polarized with a basolateral plasma

163 actions between spinal motor axons and their ensheathing glia are vital for forming and maintaining f

164 lies, gut-induced metabolic reprogramming of ensheathing glia becomes constitutive in old flies owing

165 this, we found that blocking endocytosis in ensheathing glia blocked the induction of plasticity.

166 Ensheathing glia enwrap major structures in the adult br

167 glial functions, beginning with the role of ensheathing glia in preventing ephaptic coupling, axogli

168 bset of globose basal cells and by olfactory ensheathing glia in the normal mucosa; Hes5 label disapp

169 We find ensheathing glia infiltrate specific target synaptic glo

170 uction, we discover serotonin signaling from ensheathing glia is required for experience-dependent sy

171 When the fray cDNA is expressed in the ensheathing glia of fray mutants, normal nerve morpholog

172 olfaction through metabolic reprogramming of ensheathing glia of the antennal lobe.

173 Schwann cells (SCs), ensheathing glia of the peripheral nervous system, suppo

174 oteinase-1 (MMP-1), is induced in Drosophila ensheathing glia responding to severed axons.

175 The anterior midline glia (AMG) are ensheathing glia that migrate, surround and send process

176 henotype is associated with a failure of the ensheathing glia to correctly wrap peripheral axons.

177 tless FGF receptor acts cell-autonomously in ensheathing glia to regulate process extension so as to

178 ticularly from local interneurons, instructs ensheathing glia to wrap each glomerulus.

179 uired for this critical period plasticity as ensheathing glia upregulate Draper, invade the VM7 glome

180 e gonadotropin-releasing hormone neurons and ensheathing glia which are also resident in the mesenchy

181 y neurons, non-neuronal cells, and olfactory ensheathing glia, all made from embryonic Pax7+ cells.

182 (outer and inner surface glia, cortex glia, ensheathing glia, and astrocytes), which show within-cla

183 e intestine activates JAK-STAT signalling in ensheathing glia, inducing the expression of glial monoc

184 However, whether remaining peripheral ensheathing glia, such as perineurial glia, properly enc

185 Heavily stained cells, probably ensheathing glia, surrounded the nerve fascicles.

186 Axotomy elicits Ca(2+) signals in ensheathing glia, which activates regenerative neurons t

187 il is separated from neuronal cell bodies by ensheathing glia, which as we show using dye injection e

188 CDH3 and CDH11 are expressed by olfactory ensheathing glia, which surround OSN axons in the outer

189 nt compartments by membranous processes from ensheathing glia.

190 factor Nrf2 mostly in the astrocyte-like and ensheathing glia.

191 st, the posterior midline glia (PMG) are non-ensheathing glia.

192 B(Heavy)-spectrin mutant larvae affect ensheathing glial cell polarity with delocalized PIP(2)

193 Olfactory ensheathing glial cells (OEGs) interact with a wide repe

194 that are remarkably similar to those of axon-ensheathing glial cells in unmyelinated invertebrates.

195 Furthermore, specialized olfactory-ensheathing glial cells located in the nasal cavity were

196 ein-blocking antibodies, or olfactory nerves ensheathing glial cells transplanted into the acutely in

197 thelia, including migrating GnRH neurons and ensheathing glial precursors of the migrating mass (MM),

198 coaxial non-lip progenitors; contrastingly, ensheathing granule cells derive principally from LRL.

199 to hypomyelinated mice, iOPCs are capable of ensheathing host axons and generating compact myelin.

200 Here we show that such chromosomes become ensheathed in multiple layers of endomembranes.

201 ons counted, 18% also expressed CB, 31% were ensheathed in PNN, and 7% expressed both CB and PNN.

202 , whereas unmyelinated axons were aberrantly ensheathed in Remak bundles, with increased numbers of a

203 ten fibers travel up the sides of the column ensheathed in the margins of the epidermal cells.

204 d in the cerebral cortex, pia mater, and pia-ensheathed leptomeningeal vessels in two GBCA-exposed hu

205 ular zone through the granule cell layer and ensheathe local synapses and vasculature in the inner mo

206 The primary non-motile cilium, a membrane-ensheathed, microtubule-bundled organelle, extends from

207 abeled BMDC become satellite cells: membrane-ensheathed mononucleate muscle stem cells.

208 ocytes more efficiently than fetal OPCs, and ensheathed more host axons per donor cell than fetal cel

209 Type I "glial-like" cells, with their ensheathing morphology, are mostly viewed as responsible

210 Cldn14, Adamtsl1 and Pmp2 and preferentially ensheathes motor axons.

211 ver, the remarkable ability of mutant SCs to ensheathe multiple axons is independent of mTOR signalin

212 in-1d is expressed along the axon and in the ensheathing myelin compartment.

213 on microscopy (EM) images of axons and their ensheathing myelin from both the central and peripheral

214 ingle axons, oligodendrocytes preferentially ensheathed neighboring axons.

215 y GABA transporter subtype GAT4 on processes ensheathing neuronal precursors that contain GABA.

216 sends paracrine signals to activate TRPA1 of ensheathed nociceptors to sustain mechanical allodynia.

217 They share the ensheathing of synapses and vasculature with astrocytic

218 The apparent re-ensheathing of the OS by the apical processes of the ret

219 y, vascular pattern, or SM cell and pericyte ensheathing of vessels in SM alpha-actin null mice.

220 The signals that determine whether axons are ensheathed or myelinated by Schwann cells have long been

221 omeninges, subpial astrocytes and astrocytes ensheathing penetrating blood vessels at the ventral sur

222 Smooth muscle cells (SMCs) and ensheathing pericytes (EPs), also named as terminal vasc

223 Smooth muscle cells of arterioles and ensheathing pericytes of the arteriole-capillary transit

224 yte-like cells or B-cells, sends projections ensheathing pericytes on SVZ capillaries in young mice.

225 commissures, whereas the function of the non-ensheathing PMG is unknown.

226 avid C17.2 cell-host axon contacts, and the ensheathing properties of these cells are related to the

227 ptors suggests that the extracellular matrix ensheathing RPE microvilli contains ligands for this int

228 se progression that is triggered within axon ensheathing Schwann cells and that can be ameliorated by

229 he potential contribution of peripheral axon ensheathing Schwann cells to ALS by constructing transge

230 remature formation of heminodes around early ensheathing Schwann cells, and altered nerve conduction

231 er in DRG satellite cells and nonmyelinating ensheathing Schwann cells.

232 mase (SR), localized to astrocytic glia that ensheathe synapses, converts L-serine to D-serine, an en

233 Although glia are affected by activity and ensheathe synapses, their influence on synaptic strength

234 ascular astrocytic endfeet, which completely ensheathe the brain's capillaries.

235 synchronized growth of the microtubules that ensheathe the centriole barrel.

236 a glial cell and an auxiliary cell together ensheathe the cpA soma but not cpB or cpC, suggesting a

237 lia, the processes of which often completely ensheathe the neurites of this amacrine cell.

238 esynaptic nerve terminal, Schwann cells that ensheathe the terminal bouton, and a highly specialized

239 h contained glial fibrillary acidic protein, ensheathed the chains of migrating neuroblasts.

240 we found that oligodendrocytes repetitively ensheathed the same axons multiple times before any stab

241 The glia limitans ensheathes the entire central nervous system (CNS) paren

242 The C. elegans AMsh glial cell ensheathes the NREs of 12 neurons, including the thermos

243 ious literature, our data suggest that cells ensheathing the dorsal aorta emerge from a sub-populatio

244 and seemed to be associated with glial cells ensheathing the peripheral nerves.

245 Unlike the basal lamina ensheathing the pharynx and body wall muscle, nidogen re

246 ous to the transporters in the Bergmann glia ensheathing the Purkinje cells), nor did it block the cu

247 olysis of caged Ca(2+) in astrocytic endfeet ensheathing the vessel wall was associated with an 18% i

248 es; however, there was no loss of NMSCs that ensheathe these axons.

249 7.5), KCNQ4 is also found at calyx terminals ensheathing type I vestibular hair cells where it may be

250 long, thin branches, called processes, which ensheathe vasculature and thousands of synapses.

251 Also, individual photoreceptor terminals are ensheathed within the outer plexiform layer (OPL) by the