ライフサイエンスコーパス: enteric fever

1 which is a prerequisite for transmission of enteric fever.

2 th Asia still recommend fluoroquinolones for enteric fever.

3 proportion of patients with culture-negative enteric fever.

4 e optimal assay for diagnosing patients with enteric fever.

5 to the cephalosporin ceftriaxone in treating enteric fever.

6 d Salmonella enterica serovar Sendai, causes enteric fever.

7 rs causes a febrile systemic disease, termed enteric fever.

8 need to be familiar with shifting trends in enteric fever.

9 c systemic biomarkers can be detected during enteric fever.

10 omics could lead to improved diagnostics for enteric fever.

11 ehavior in individuals with recent suspected enteric fever.

12 nfections in humans which are referred to as enteric fever.

13 riably predictive of blood culture-confirmed enteric fever.

14 tive bacteria that cause gastroenteritis and enteric fever.

15 iseases ranging from mild gastroenteritis to enteric fever.

16 ed for fatal infection in the mouse model of enteric fever.

17 om mild gastroenteritis to host-disseminated enteric fever.

18 comparable to the route it takes in cases of enteric fever.

19 aratyphi), which are the causative agents of enteric fever.

20 ures and fewer relapses in culture-confirmed enteric fever.

21 r providing comprehensive protection against enteric fever.

22 ecificity of the DPPT assay for diagnosis of enteric fever.

23 accurate, and low-cost assays for diagnosing enteric fever.

24 rt for the WHO recommendations on control of enteric fever.

25 arm); 87 (26.7%) had blood culture-confirmed enteric fever.

26 can inform public health policies to prevent enteric fever.

27 tures and less relapses in culture-confirmed enteric fever.

28 and obtained blood cultures to evaluate for enteric fever.

29 a that can inform public health responses to enteric fever.

30 patients enrolled were culture-positive for enteric fever.

31 her suspected or blood culture confirmed for enteric fever.

32 highly recommended to prevent the spread of enteric fever.

33 terize disease incidence among patients with enteric fever.

34 We enrolled 2939 patients with suspected enteric fever.

35 njugate vaccine as a preventive tool against enteric fever.

36 pitals and determinants of culture-confirmed enteric fever.

37 inst widespread morbidity and mortality from enteric fever.

38 ct medical economic costs to treat a case of enteric fever.

39 ct medical economic costs to treat a case of enteric fever.

40 n areas, alongside other measures to prevent enteric fever.

41 exceeded the threshold for "high burden" of enteric fever (100 per 100 000 person-years).

42 77 participants had culture-confirmed enteric fever (62 Salmonella enterica serotype Typhi and

43 Enteric fever, a bacterial infection caused by Salmonell

44 Enteric fever affects more than 25 million people annual

45 In participants developing enteric fever after oral infection, marked transcription

46 e potential to improve clinical outcomes for enteric fever, allowing rapid diagnosis and treatment, a

47 ated a high burden of hospitalization due to enteric fever among children aged <5 years in Bangladesh

48 oth reported symptoms and clinical signs, of enteric fever among patients participating in the Survei

49 The incidence of enteric fever, an invasive bacterial infection caused by

50 432 individuals with blood culture-confirmed enteric fever and 2,011 controls from Vietnam.

51 thening the existing surveillance system for enteric fever and antimicrobial resistance at the nation

52 In contrast, enteric fever and invasive NTS infections (iNTS) are eac

53 for the rapid and culture-free diagnosis of enteric fever and non-typhoidal Salmonella bacteremia.

54 artments at 2 study hospitals with suspected enteric fever and performed blood cultures.

55 s not responsible for increased frequency of enteric fever and suggest that environmental changes may

56 ices of resources used to diagnose and treat enteric fever, and procedure frequencies received at the

57 are important for late stages of Salmonella enteric fever, and that they probably contribute to the

58 sible metabolites that can be used to detect enteric fever, and unlocks the potential of this method

59 which distinguishes malaria from sepsis and enteric fever; and the cerebral Malaria Meta-Signature,

60 responsible for more than 2 million cases of enteric fever annually.

61 ella Typhi and Salmonella Paratyphi A during enteric fever are poorly understood.

62 ng etiology and trends of drug resistance in enteric fever are scarce.

63 e a radical reduction of the significance of enteric fever as a global public health problem in the n

64 we enrolled 5736 participants with suspected enteric fever at 2 study hospitals.

65 n Asia Project (SEAP) to assess incidence of enteric fever at 6 study hospitals in 3 countries.

66 We report the burden of enteric fever at selected sites of Karachi, Pakistan.

67 ged 14-45 years) with criteria for suspected enteric fever (body temperature >/=38.0 degrees C for >/

68 lity of current methods likely underestimate enteric fever burden.

69 r Typhi (S Typhi) has been the main cause of enteric fever, but now S Typhi is being displaced by inf

70 Enteric fever can impose a considerable economic burden

71 Enteric fever can impose a considerable economic burden

72 hese new estimates of the cost of illness of enteric fever can improve evaluation and modeling of the

73 Enteric fever can lead to prolonged hospital stays, clin

74 We replicated this association in 595 enteric fever cases and 386 controls from Nepal and also

75 to the longitudinal antibody responses among enteric fever cases and used the joint distributions of

76 laboratory data from blood culture-confirmed enteric fever cases enrolled in SEAP hospitals and assoc

77 Of the 8705 blood culture-confirmed enteric fever cases enrolled, we identified 6 deaths (ca

78 We screened suspected enteric fever cases from 6 hospitals in Bangladesh, Nepa

79 Enteric fever cases have increased during the last 3 yea

80 the guidelines and training for treatment of enteric fever cases in Africa are sorely needed to help

81 timicrobial resistance (AMR) among confirmed enteric fever cases in Bangladesh, Nepal, and Pakistan.

82 through June 2019, 2243 laboratory-confirmed enteric fever cases were detected in 2 study hospitals;

83 rovisional diagnoses, but 31% (1147/3754) of enteric fever cases were not covered by initial therapy;

84 During 2008-2012, 2341 enteric fever cases were reported, 80% typhoid and 20% p

85 e or histopathology confirmed total 15 (11%) enteric fever cases with ileal perforation are similar t

86 ere obtained from all suspected or confirmed enteric fever cases.

87 We enrolled 8,705 blood culture confirmed enteric fever cases: 4,873 (56%) from Bangladesh, 1,602

88 creened 30 809 outpatients resulting in 1819 enteric fever cases; 1935 additional cases were enrolled

89 We report the first pediatric case of enteric fever caused by Salmonella enterica serotypes Ty

90 The burden of enteric fever caused by Salmonella enterica serovars Typ

91 Enteric fever caused by Salmonella enterica serovars Typ

92 Enteric fever caused by Salmonella enterica Typhi and Sa

93 The gold standard for diagnosis of enteric fever caused by Salmonella Typhi or Salmonella P

94 Enteric fever caused by Salmonella Typhi remains a major

95 There was an increasing trend in enteric fever caused by SPA during the last 2 decades (P

96 Enteric fever, caused by Salmonella enterica serovar Typ

97 Enteric fever, caused by Salmonella enterica serovars Ty

98 Enteric fever, caused by Salmonella Typhi and Salmonella

99 Enteric fever, caused by the human-restricted bacteria S

100 Enteric fever causes substantial morbidity and mortality

101 Adjusted incidence rates of enteric fever considered patients in the six tertiary ho

102 highlight illness severity and the need for enteric fever control measures, including the use of typ

103 munosorbent assay in patients with suspected enteric fever, controls with other febrile illnesses, an

104 These new estimates of enteric fever cost of illness can improve evaluation and

105 ther explored with the aim of creating a new enteric fever diagnostic to work in conjunction with TCV

106 Precise enteric fever disease burden data are needed to inform p

107 hildren bear a substantial proportion of the enteric fever disease burden in endemic areas.

108 Recognizing that enteric fever disproportionately affects the poorest and

109 There is an urgency to the global control of enteric fever due to the escalating problem of antimicro

110 s from patients with blood culture-confirmed enteric fever enrolled from surveillance studies in Bang

111 etory response, whereas serotypes that cause enteric fever establish systemic infection through their

112 f antigens as good candidates to demonstrate enteric fever exposure.

113 We need a sustained effort within the enteric fever field to accelerate, validate, and ultimat

114 ver and inpatients with clinically suspected enteric fever from all 6 SEAP study hospitals were eligi

115 PT assay in distinguishing culture-confirmed enteric fever from alternative aetiologies using receive

116 mples from 5 patients with culture-confirmed enteric fever from Bangladesh in comparison to 3 healthy

117 e differentiation of Salmonella spp. causing enteric fever from nontyphoidal Salmonella is essential

118 curately distinguish blood culture-confirmed enteric fever from other febrile syndromes.

119 fever; patients with blood culture-confirmed enteric fever from the hospital laboratories not capture

120 tion, the median cost of illness per case of enteric fever from the patient and caregiver perspective

121 ls in Nepal to estimate the cost per case of enteric fever from the perspectives of patients, caregiv

122 lla enterica, the causative agent of typhoid/enteric fever, from this period of transformation in Cre

123 Over the last few decades, the control of enteric fever has focused primarily on improved water an

124 The health care-adjusted incidence of enteric fever hospitalization among children <15 years o

125 roject (SEAP) data to estimate the burden of enteric fever hospitalization among children aged <15 ye

126 Salmonella Typhi contributed most to the enteric fever hospitalization incidence (277/100 000 chi

127 Factors independently associated with enteric fever hospitalization included fever duration, d

128 timate the health care-adjusted incidence of enteric fever hospitalization, and conducted univariable

129 more likely to be blood culture positive for enteric fever; however, the effect was not statistically

130 performed population-based surveillance for enteric fever in 1 urban catchment (Kathmandu) and 1 per

131 assay achieved high diagnostic accuracy for enteric fever in a highly endemic community.

132 ing of the clinical severity and sequelae of enteric fever in Africa, Asia, and India.

133 m vaccine introduction, the Surveillance for Enteric Fever in Asia Project (SEAP) conducts prospectiv

134 Here, we analyzed Surveillance for Enteric Fever in Asia Project (SEAP) data to estimate th

135 4 hospitals as part of the Surveillance for Enteric Fever in Asia Project (SEAP) II in Pakistan.

136 text of the population-based Surveillance of Enteric Fever in Asia Project (SEAP) in Bangladesh, Nepa

137 The Surveillance for Enteric Fever in Asia Project (SEAP) is a multicenter, m

138 The Surveillance for Enteric Fever in Asia Project (SEAP) is a prospective st

139 used a hybrid model in the Surveillance for Enteric Fever in Asia Project (SEAP) to assess incidence

140 We established the Surveillance for Enteric Fever in Asia Project (SEAP) to inform these str

141 tients participating in the Surveillance for Enteric Fever in Asia Project (SEAP), a 3-year surveilla

142 The Surveillance for Enteric Fever in Asia Project (SEAP), a prospective surv

143 As a part of the Surveillance for Enteric Fever in Asia Project (SEAP), we investigated th

144 repalanchok) as part of the Surveillance for Enteric Fever in Asia Project (SEAP).

145 tilization in Nepal for the Surveillance for Enteric Fever in Asia Project .

146 ization survey used for the Surveillance for Enteric Fever in Asia Project in Nepal, we incorporated

147 results show substantial economic burden of enteric fever in Bangladesh, with higher costs for patie

148 ritis but also cause invasive infections and enteric fever in certain hosts (young children in sub-Sa

149 that parallel their unique ability to cause enteric fever in humans.

150 Data on the incidence of enteric fever in Myanmar are scarce.

151 es should no longer be used for treatment of enteric fever in Nepal.

152 paratyphi A, the second most common cause of enteric fever in Southeast Asia, is a habitant of and a

153 are the relative proportion of children with enteric fever in the age groups <5 years, 5-9 years, and

154 Enteric fever in the United States has been primarily as

155 Enteric fever in the United States is primarily associat

156 We aimed to determine the burden of enteric fever in three urban sites in Africa and Asia.

157 is critical for generating population-based enteric fever incidence estimates from facility-based su

158 sia Project (SEAP) is a prospective study of enteric fever incidence in Nepal, Bangladesh, and Pakist

159 Enteric fever incidence is high in Yangon, Myanmar, warr

160 d be incorporated into estimation models for enteric fever incidence.

161 eneity in febrile illness, care seeking, and enteric fever incidence.

162 veillance study, characterized the burden of enteric fever, including illness severity, in selected s

163 , nonmedical, and indirect costs per case of enteric fever incurred since illness onset by phone afte

164 Enteric fever is a major global problem, the burden of w

165 Enteric fever is a serious public health concern in many

166 Enteric fever is a serious public health concern.

167 Enteric fever is endemic in Nepal and its economic burde

168 Enteric fever is estimated to affect 11-20 million peopl

169 The elimination of enteric fever is now becoming a real possibility, but ne

170 Enteric fever is the only bacterial infection of humans

171 tect amplified target cDNA in all 5 cases of enteric fever; no detectable signal was seen in the heal

172 tten by his personal physician suggests that enteric fever, not pneumonia per se, was the disorder th

173 with 120 Vietnamese patients with suspected enteric fever, of whom 89 had confirmed typhoid fever.

174 r 1029 patients with blood culture-confirmed enteric fever or with a nontraumatic terminal ileal perf

175 l studies characterizing the transmission of enteric fever organisms through sewage and water, discus

176 vironmental sampling for the surveillance of enteric fever organisms to provide data on community-lev

177 areas were based on residential addresses of enteric fever patients using study facilities; clusters

178 equired given the large numbers of suspected enteric fever patients with a negative culture.

179 were collected from blood culture-confirmed enteric fever patients, blood culture-negative febrile p

180 l antibody responses were comparable between enteric fever patients, patients with blood culture-nega

181 days; inpatients with suspected or confirmed enteric fever; patients with blood culture-confirmed ent

182 as a major contributor to resistance against enteric fever, presumably through antigen presentation.

183 on and modeling of the costs and benefits of enteric fever prevention and control measures, including

184 on and modeling of the costs and benefits of enteric fever-prevention measures.

185 Morbidity and mortality from enteric fever primarily occur in lower-income countries,

186 Individual data from 2092 patients with enteric fever randomized into 4 trials in Kathmandu, Nep

187 Enteric fever remains a major cause of morbidity in deve

188 Enteric fever remains a public health concern in communi

189 Diagnosis of enteric fever remains frustrated by the nonspecific clin

190 Typhoid (enteric fever) remains a major cause of morbidity and mo

191 The clinical features of enteric fever reviewed here differ between younger and o

192 thcare seeking for acute febrile illness and enteric fever risk in these communities, and should be i

193 op more sensitive and scalable approaches to enteric fever surveillance and generate invaluable epide

194 We conducted enteric fever surveillance in Bangladesh from 2004 throu

195 in Asia Project (SEAP) conducts prospective enteric fever surveillance in Bangladesh, Nepal, and Pak

196 89 S Typhi strains isolated from prospective enteric fever surveillance studies in Nepal, Bangladesh,

197 ns; however, infection of mice results in an enteric fever that resembles human typhoid fever and has

198 the only routinely used control measures for enteric fever, the assessment of novel diagnostics, new

199 g the utility of these alternative drugs for enteric fever treatment.

200 inferior to each other for culture-confirmed enteric fever treatment.

201 inferior to each other for culture-confirmed enteric fever treatment.

202 y was to estimate the cost of illness due to enteric fever (typhoid and paratyphoid) at selected site

203 udy was to estimate the cost of illness from enteric fever (typhoid and paratyphoid) at selected site

204 y to assess the economic burden of pediatric enteric fever (typhoid and paratyphoid) in Bangladesh.

205 Enteric fever was associated with locally established pa

206 derstanding of the disease formerly known as enteric fever was transformed, offering new possibilitie

207 vestigate metabolite signals associated with enteric fever we performed two dimensional gas chromatog

208 imperfect reference standard diagnostics for enteric fever, we used Bayesian latent class models, inc

209 f 8705 patients with blood culture-confirmed enteric fever were hospitalised.

210 ical improvement and high relapse burden for enteric fever, whereas the fluoroquinolone gatifloxacin

211 rica serovar Paratyphi A is a major cause of enteric fever, with a microbiological history dating to

212 reduce the sensitivity of blood culture for enteric fever, with implications for both clinical care