ライフサイエンスコーパス: envelope

1 nd forces are transmitted across the nuclear envelope.

2 aquatic flight, expanding their performance envelope.

3 egulate all cargo traffic across the nuclear envelope.

4 T machinery to drive the construction of its envelope.

5 f the origin of E. gracilis's middle plastid envelope.

6 cture of the DNA outside the intrinsic B-DNA envelope.

7 higher-order structures that form the viral envelope.

8 ming HIV-1 particles carrying wild-type (WT) envelope.

9 lamin A/C is a key component of the nuclear envelope.

10 near binding of the genome along the nuclear envelope.

11 e initial interaction of PAF26 with the cell envelope.

12 inery maintains the integrity of the nuclear envelope.

13 nd a thin cylindrical projection of the cell envelope.

14 sinB have conserved functions at the nuclear envelope.

15 crotubules that traverse the nascent nuclear envelope.

16 ered, giving rise to a persistent amyloplast envelope.

17 d between the CA lattice and the viral lipid envelope.

18 but remains attached via a thread of nuclear envelope.

19 t on molecular targets at the bacterial cell envelope.

20 ein network that underlies the inner nuclear envelope.

21 wing to the complex structure of the nuclear envelope.

22 o secrete proteins across their complex cell envelopes.

23 unctionality of gram-negative bacterial cell envelopes.

24 concealment was implemented by use of sealed envelopes.

25 elivery of large molecules across their cell envelopes.

26 closed using hidden Markov modeling of power envelope activity.

27 ogether, this study reveals that the nuclear envelope acts as a reservoir, maintaining COP1 poised fo

28 In addition, we show inhibition of a non-enveloped adenovirus.

29 process of membrane fusion between the viral envelope and a cellular membrane.

30 s for PIC targeting are a Gram-negative cell envelope and a unique cell surface antigen; therefore, t

31 d that OsPHT2;1 localized to the chloroplast envelope and functioned as a low-affinity Pi transporter

32 risons of shape and integrity of the nuclear envelope and its resistance to stresses found that both

33 17 females) entrained to the auditory speech envelope and lip movements (mouth opening) when listenin

34 The LINC complex spans the nuclear envelope and mediates nuclear mechanotransduction, the p

35 teractions of chromatin with the surrounding envelope and nuclear bodies.

36 It is situated on the virion envelope and plays key roles in LASV growth, cell tropis

37 t of channels can explain the characteristic envelope and temporal organisation of the [Ca2+]i-spike

38 sialylated glycans, fusion between the viral envelope and the host membrane, and the formation of a f

39 n independently explain the typical decaying envelope and the progressive spacing of the spikes.

40 d different abilities to diffuse across cell envelopes and interact with lipids and intracellular nuc

41 ed polysaccharides of the mycobacterial cell envelope, and are targets of anti-tuberculosis drug etha

42 acting with virions, destabilizing the viral envelope, and driving virus aggregation and/or interviri

43 three cocoon sections (outer envelope, inner envelope, and the intermediate section that separates th

44 Our atomistic analysis unveils the role of envelope anisotropy, valley interference and dopant plac

45 Our understanding of the mechanisms of envelope assembly and maintenance has increased tremendo

46 smic components are displaced before nuclear envelope assembly by the movement of chromosomes to a de

47 tion between stomatal regulation and nuclear envelope-associated proteins, and adds two new players t

48 Notably, capsids acquired envelopes at axonal varicosities and terminals where the

49 the disruption is generated by aberrant cell envelope biogenesis.

50 lute-binding proteins, oxidoreductases, cell envelope biosynthesis enzymes, and others.

51 tion begins with germinal vesicle or nuclear envelope breakdown (GVBD) and is critical for oocyte qua

52 phase and prophase but released upon nuclear envelope breakdown (NEBD) by the action of Cdk1.

53 The mechanism of local nuclear envelope breakdown in a closed mitosis therefore closely

54 ed mitosis therefore closely mirrors nuclear envelope breakdown in open mitosis(3), revealing an unex

55 As after chromosome condensation and nuclear envelope breakdown is unknown.

56 Since nuclear envelope breakdown occurs during mitosis in metazoan cel

57 n mice after birth, is essential for nuclear envelope breakdown prior to progression to metaphase and

58 mitotic establishment corresponds to nuclear envelope breakdown, which requires a decisive shift in t

59 am-positive and Gram-negative bacterial cell envelope, but do not rupture or lyse bacteria.

60 COP1 preferentially localizes to the nuclear envelope, but it is released from the nuclear envelope i

61 involve alpha-catenin capture at the nuclear envelope by nesprin upon its relaxation, thereby regulat

62 gnetite (Fe(3)O(4)) or greigite (Fe(3)S(4)), enveloped by a lipid bilayer membrane, produced by magne

63 in social epidemiology that should always be enveloped by a thorough understanding of how systems and

64 Gram-negative pathogens are enveloped by an outer membrane that serves as a double-e

65 uth America, with those assemblages becoming enveloped by assemblages from the subtropics.

66 pherical nanoparticles tend to be completely enveloped by host membranes, whereas low sphericity nano

67 SINE1, an outer nuclear envelope component of a plant Linker of Nucleoskeleton a

68 sponding cyclopentane derivatives with fixed envelope conformation of the five-membered ring.

69 A unique, protective cell envelope contributes to the broad drug resistance of the

70 ation were assessed using band-limited power envelope correlation, whereas those on transient functio

71 ineage targeting the fusion peptide of HIV-1 envelope creating a critical bifurcation, with only one

72 N-damaged animals in their use of energy and envelope cues to perform the task.

73 ound only weak correlations between MreB and envelope curvature in the cylindrical part of cells.

74 omputational analysis also demonstrates that envelope deformation is increased by adhesion to nanopat

75 Ascoviruses are large, enveloped DNA viruses that induce remarkable changes in

76 in addition to light-dependent activation, "envelope docking" of ACCase permits fine-tuning of fatty

77 A plant-derived dengue envelope domain III (EDIII) protein was used as the anti

78 nd isolated 15 DENV3 TS mAbs recognizing the envelope (E) glycoprotein.

79 Amino acid 159 of the envelope (E) protein is reportedly implicated in the dif

80 es against flaviviral species.IMPORTANCE The envelope (E) protein is the dominant target of neutraliz

81 Zika virus (ZIKV) envelope (E) protein is the major target of neutralizing

82 ), allosterically block CD4 binding to HIV-1 envelope (Env) and inhibit CD4-induced structural change

83 neutralizing antibodies (NAbs) against HIV-1 Envelope (Env) at single-residue resolution, using Cys l

84 Envelope (Env) glycoprotein of human immunodeficiency vi

85 neutralizing and non-neutralizing anti-HIV-1 Envelope (Env) mAbs, using concentrations <= 1 mug/mL, t

86 se transcriptase (RT), integrase (IN) and/or envelope (env) regions.

87 having human A32, 7B2, or PGT145 anti-HIV-1 envelope (Env) specificities paired with a human anti-CD

88 followed by boosting with a stabilized BG505-envelope (Env) trimer.

89 We identified increased expression of envelope (Env) trimers at the cell surface and increased

90 HIV-1 envelope (Env) trimers, stabilized in a prefusion-closed

91 The HIV-1 envelope (Env) undergoes conformational changes during i

92 eceptors CTLA-4, PD-1 or OX40 along with HIV envelope (Env) vaccines to rhesus macaques and bnAb immu

93 pplemental infusion of cell-associated HIV-1 envelope (Env).

94 low mass of the planet candidate make common-envelope evolution less likely.

95 Both Golgi and nuclear envelope exhibit MTOC activity utilizing either AKAP9, o

96 he related physics and determine the working envelope for maintaining robust superhydrophobicity, in

97 in a dominant and damaging effect on nuclear envelope formation that correlates with microcephaly in

98 separation may contribute to other critical envelope functions, including interphase repair(8-13) an

99 driving virus aggregation and/or intervirion envelope fusion.

100 erous integrated viral genes including viral envelope genes that are part of LTR retrotransposons.

101 ombinant viruses constructed with individual envelope genes that were obtained from plasma of six ind

102 ive studies with subtype A BG505-derived HIV envelope glycoprotein (Env) immunogens have revealed tha

103 , viral escape through mutation of the HIV-1 envelope glycoprotein (Env) limits clinical applications

104 nformation of HIV-1 Env.IMPORTANCE The HIV-1 envelope glycoprotein (Env) opens in response to recepto

105 riggers serial conformational changes in the envelope glycoprotein (Env) trimer that result in the fu

106 The HIV-1 envelope glycoprotein (Env) trimer, composed of gp120 an

107 Well-ordered HIV-1 envelope glycoprotein (Env) trimers are prioritized for

108 he immunogenicity of native-like recombinant envelope glycoprotein (Env) trimers based on viral seque

109 ction against HCMV infection, and the virion envelope glycoprotein B (gB) serves as a major target of

110 Efficient engagement with the envelope glycoprotein membrane-proximal external region

111 sed design of several epitopes of the HCV E2 envelope glycoprotein to engineer its antigenic properti

112 cted for viruses with mutations in the viral envelope glycoprotein, gp41.

113 he high-mannose glycans found on the surface envelope glycoprotein-120 (gp120).

114 vity of SERINC5 with remodeling of the HIV-1 envelope glycoprotein.

115 The envelope glycoproteins (Envs) of HIV-1 are embedded in t

116 and microbicides that target glycans on the envelope glycoproteins (Envs) of HIV-1.

117 ata suggest that HSV-1 gC protects the viral envelope glycoproteins essential for entry, including gB

118 The envelope glycoproteins Gn and Gc form heterodimers that

119 zation through structure-based design of the envelope glycoproteins is a promising route to an effect

120 in perinuclear vesicle-like structures near envelope glycoproteins or mitochondria.

121 hors Gag to the plasma membrane and recruits envelope glycoproteins to virus assembly sites.

122 (M) segment of the viral genome encodes two envelope glycoproteins, G(N) and G(C), which together fo

123 of what we know about the mycobacterial cell envelope has been gleaned from model actinobacterial spe

124 Nuclear envelope herniations (blebs) containing FG-nucleoporins

125 lex network connecting in vivo fitness, cell envelope homeostasis and resistance to antibiotics.

126 of Mla; providing another link between cell envelope homeostasis and stringent response.

127 of how cysteine residues could contribute to envelope homeostasis by functioning as redox switches.

128 smantling and later reassembling the nuclear envelope in an 'open mitosis' or by reshaping an intact

129 During mitosis, however, the nuclear envelope in animal and plant cells disassembles, allowin

130 sphates and carboxylate groups from the cell envelope in the bioassociation of Eu(III).

131 Among pretreatment envelopes, increased probability of using CXCR4 and grea

132 cocoons at all three cocoon sections (outer envelope, inner envelope, and the intermediate section t

133 ulates ESCRT disassembly to maintain nuclear envelope integrity and proper ER architecture.

134 Cell shape and cell-envelope integrity of bacteria are determined by the pep

135 Maintenance of nuclear envelope integrity requires the EndoSomal Complexes Requ

136 nvelope, but it is released from the nuclear envelope into the nucleoplasm following Erk1/2 inactivat

137 leads to rapid COP1 release from the nuclear envelope into the nucleoplasm where it degrades COP1 sub

138 The Mycobacterium tuberculosis cell envelope is a critical interface between the host and pa

139 A/C, a scaffolding component of the nuclear envelope, is critical to maintaining the NMJ in mice.

140 es with other viral proteins including HIV-1 envelope, Lassa virus glycoprotein complex, and influenz

141 ly smaller until 2 dpf and display perturbed enveloping layer (EVL) integrity and cell protrusions at

142 This Review describes the trans-envelope lipid transport systems that have been identifi

143 protein large (MmpL) proteins transport cell envelope lipids and siderophores that are important for

144 We therefore isolated nuclear envelope lipids from human kidney cells, analyzed their

145 e probabilities for the classification of an envelope localization.

146 ons support the possibility that the nuclear envelope may balance significant mechanical stresses in

147 at CA-MRSA success might be driven by a cell-envelope mediated selective advantage across diverse che

148 In total, we identified 38 envelope membrane intrinsic or associated proteins exhib

149 ng that cholesterol depletion from the HIV-1 envelope membrane reduces virus entry.

150 g for three small plastidial proteins of the envelope membrane that interact with the alpha-carboxylt

151 chloroplast PG assembly occurs at the inner envelope membrane, FAD4 was primarily associated with th

152 To survive within this enveloping membrane, the organism must take in nutrients

153 ted as the translocon at the outer and inner envelope membranes of chloroplast (TOC-TIC) complex, upo

154 ally visible cellular compartments that lack enveloping membranes, recently termed biomolecular conde

155 Electron spin echo envelope modulation (ESEEM) experiments suggest that the

156 Cochlear-implant (CI) users rely on temporal envelope modulations (TEMs) to understand speech, and cl

157 as found that FNA broke down a range of cell envelope molecules.

158 entify AKAP6 as key component of the nuclear envelope MTOC.

159 ike varicosity clusters (CGRP+ baskets) that enveloped myenteric nerve cell bodies.

160 detected activated ISG-expressing microglia enveloping NA-containing neuritic plaques in postmortem

161 By contrast, non-enveloped naked virions are shed in faeces and stripped

162 oned on the shortest nuclear axis at nuclear envelope (NE) breakdown.

163 bility barrier depends on closure of nuclear envelope (NE) holes.

164 ic dynein, kinesin, and actin to the nuclear envelope (NE) in other cell types.

165 The nuclear envelope (NE) is continuous with the endoplasmic reticul

166 e induced by stretch stimulation and nuclear envelope (NE) proteins including nesprins, SUN2, and lam

167 ss contributes to subsequent mitotic nuclear envelope (NE) remodeling remains unclear.

168 The nuclear envelope (NE) undergoes dynamic remodeling to maintain N

169 The nucleus is delineated by the nuclear envelope (NE), which is a double membrane barrier compos

170 Paramyxoviruses are enveloped, nonsegmented, negative-strand RNA viruses tha

171 plitude coupling (PAC), the amplitude of the envelope of a faster oscillation is larger within a phas

172 The cell envelope of Gram-negative bacteria is a multilayered str

173 -Pal is a multiprotein system present in the envelope of Gram-negative bacteria.

174 The cell envelope of Gram-positive bacteria generally comprises t

175 The gB in the native envelope of HSV-1 had reduced reactivity with antibodies

176 Thus, seagull is a convenient envelope of lasso variants.

177 lular envelopment and incorporation into the envelope of released extracellular virions.

178 described, each designed to breach the cell envelope of target bacteria.

179 lipids could be inferred from changes in the envelope of the C-H stretch.

180 e-specific chitoporin, VcChiP, from the cell envelope of the V. cholerae type strain O1.

181 ass through the middle and innermost plastid envelopes of E. gracilis by machinery homologous to the

182 ctrum (that is, to change the comb's carrier-envelope offset frequency) and make excursions beyond th

183 all (a few Earth masses) hydrogen and helium envelope on timescales of several billion years, implyin

184 emoving barriers to the external world (cell envelopes) or by destroying their genetic identity (DNA)

185 d that the two innermost E. gracilis plastid envelopes originated from the primary plastid, while the

186 articles are secreted basolaterally as quasi-enveloped particles and apically as naked virions, recap

187 protects the bacteria against increased cell-envelope permeability under subinhibitory cefoxitin trea

188 hat both mutations result in similar nuclear envelope perturbations that were reversed in the isogeni

189 tocurrents can be used to detect the carrier-envelope-phase (CEP) of short optical pulses, and enable

190 We found that broadband slow-wave modulation enveloped posterior cortex when subjects initially becam

191 n, COP1 is rapidly released from the nuclear envelope, promoting the degradation of its nuclear subst

192 Assembling the envelope properly and maintaining its integrity are matt

193 The HIV-1 envelope protein (Env) is the target of neutralizing ant

194 The trimeric HIV-1 Envelope protein (Env) mediates viral-host cell fusion v

195 face, we sought to determine whether the HIV envelope protein (Env) was genotypically and phenotypica

196 virus-based vector (ALVAC) together with an envelope protein (gp120) adjuvanted in alum.

197 ion of HCV with hepatic cells by binding HCV envelope protein 1 to prevent fusion.

198 pe 1 CD4(+) T cell responses against the SIV envelope protein and failed to protect macaques from vir

199 ring which a topological switch of the large envelope protein confers infectivity.

200 mmunizations, we studied recall responses to envelope protein domain III (DIII).

201 otifs, was constructed to display ten dengue envelope protein domain III (ED3)-targeting aptamers int

202 e mature and inferred-germline Ab binding to envelope protein domain III of ZIKV and other flavivirus

203 sential protein of the SARS-CoV-2 virus, the envelope protein E, forms a homopentameric cation channe

204 we summarize current knowledge on flavivirus envelope protein glycosylation and its impact on viral i

205 ody-based countermeasures targeting the ZIKV envelope protein have been hampered by concerns for cros

206 ral agents that target mannose sugars on the envelope protein of HIV-1.

207 ling a concerted, fine-tuned activity of two envelope protein species, is unique among CoVs, but remi

208 otic telomeres and interact with the nuclear envelope protein SUN1, with a possible crucial role in m

209 ch signaling in MEG-01 cells where the virus envelope protein was shown to interact with TAL-1, a hos

210 with other flaviviruses that share a similar envelope protein, such as dengue virus, West Nile virus,

211 rough the action of the viral glycoprotein M envelope protein.

212 2-domain of the spike-protein and the dengue envelope-protein.

213 n controls nucleocapsid interaction with the envelope proteins for virus exit.

214 We go on to identify cell envelope proteins that are necessary for the import of P

215 polyclonal antibodies against ZIKV and DENV envelope proteins utilizing nine ZIKV and twelve DENV st

216 four related to the scale of the interaction envelope, ranging from fine-scale manipulations directed

217 hly sensitive to the geometry of the nuclear envelope, ranging from twofold to an order magnitude lar

218 Tospoviridae is a family of enveloped RNA plant viruses that infect many field crops

219 oronaviruses are a family of positive-strand enveloped RNA viruses that includes the severe acute res

220 ience extensive nuclear deformation, nuclear envelope rupture, and DNA damage.

221 formation-induced DNA damage, unlike nuclear-envelope-rupture-induced DNA damage, occurs primarily in

222 Our findings implicate Cdc42 in nuclear envelope sealing and ER remodeling, where it regulates E

223 The nuclear envelope segregates the genome of Eukaryota from the cyt

224 Ebola virus (EBOV) is an enveloped, single-stranded RNA virus that can cause Ebol

225 n of IgG against the envelope V2 loop and of envelope-specific CD4(+) T cell responses.

226 Despite higher magnitude of envelope-specific responses in HVTN 100 compared to HVTN

227 ciently restricted the entry mediated by the envelope spike proteins of other human coronaviruses, in

228 eins, G(N) and G(C), which together form the envelope spikes.

229 ermit high-avidity binding of trimeric HIV-1 envelope spikes.

230 etween the OM and PG and is crucial for cell envelope stability(4); however, most other Gram-negative

231 in B1 plays an important role in the nuclear envelope stability, the regulation of gene expression, a

232 ngs to propose a model of Gram-negative cell envelope stabilization that includes cell cycle control

233 e critical for the growth of S. mutans under envelope stress conditions.

234 A2 transcription is largely dependent on the envelope stress regulator LiaFSR.

235 responses but dispensable for SpxA2-mediated envelope stress responses.

236 gnaling to the actomyosin cortex via nuclear envelope stretch-sensitive proteins, up-regulating cell

237 The cell envelope structurally and functionally varies across the

238 ontinuum mechanical properties, multilayered envelope structure, and adhesion interaction conditions.

239 iruses averaged 76 um in diameter and had an envelope studded with crown-like, electron-dense spikes.

240 Envelope subunit antigens have the potential to overcome

241 of hearing loss on EEG correlates of speech envelope synchronization in cortex.

242 glutamate, thereby coupling protein and cell envelope synthesis with the metabolic status of the cell

243 Gram-negative bacteria have a cell envelope that comprises an outer membrane (OM), a peptid

244 conformations delineate a cryptic inhibitor envelope that expands the observed footprint of AZ1 in t

245 ong association and form a capsule structure enveloping the cell and/or take the form of exopolysacch

246 ate the equation of state of the white dwarf envelope (the region surrounding the stellar core that c

247 anchors centrosomal proteins to the nuclear envelope through its spectrin repeats, acting as an adap

248 The resistance of the envelope to bending, quantified by the flexural stiffnes

249 CoV-2 utilises the Spike glycoprotein on the envelope to recognise and bind the human receptor ACE2.

250 actin-dependent forces acting on the nuclear envelope to remodel nuclear shape, which might be a defi

251 ectodomain to confer specificity for the HIV envelope, to mitigate HIV-induced pathogenesis in bone m

252 Hazara nairovirus (HAZV) is an enveloped trisegmented negative-strand RNA virus classif

253 compare costs and outcomes of antibacterial envelope (TYRX) use adjunctive to standard-of-care infec

254 them), and found that variation in the outer envelope underlies the differences in architecture betwe

255 and of plastid subfractions (thylakoids and envelopes), using HPLC high-resolution tandem mass spect

256 y modeling predicts that contact between the envelope V1 loop and the antibody impacts V3 loop bnAb s

257 ated with the elicitation of IgG against the envelope V2 loop and of envelope-specific CD4(+) T cell

258 ceptor maps to a predicted protrusion in the envelope V3 loop, this viral determinant does not direct

259 At baseline, COP1 attaches to the nuclear envelope via interaction with translocated promoter regi

260 antiviral protein that blocks the release of enveloped viral particles by linking them to the membran

261 ecretory pathway for the transport of single enveloped viral particles from the trans-Golgi network w

262 roduce two antigenically distinct infectious enveloped virions termed intracellular mature virions an

263 quired for infection by both naked and quasi-enveloped virions.

264 RNPA2B1 plays a key role in the transport of enveloped virus from its site of assembly to the extrace

265 ein (N) is an immunodominant antigen in many enveloped virus infections.

266 They also mediate the entry of enveloped viruses by binding PS in the virion membrane.

267 enveloped archaeal viruses have evolved from enveloped viruses by shedding the membrane, indicating t

268 Enveloped viruses enter cells via a process of membrane

269 To enhance infection, enveloped viruses exploit adhesion molecules expressed o

270 ne-interacting peptides that inhibit diverse enveloped viruses in vitro and in vivo Peptide therapeut

271 affect viral membrane fusion.IMPORTANCE Many enveloped viruses infect cells via fusion to endosomes,

272 Numerous peptides inhibit the entry of enveloped viruses into cells.

273 Infection by enveloped viruses involves fusion of their lipid envelop

274 We hypothesize that entry by other enveloped viruses may also use sequential processes of a

275 To achieve this, enveloped viruses must first fuse their membrane with th

276 display broad antiviral activity against all enveloped viruses tested, including herpesviruses, Measl

277 -1, unlike members of many other families of enveloped viruses, does not appear to require the ESCRT-

278 vents leading to the entry of representative enveloped viruses, highlighting the strategies they use

279 Matrix proteins are encoded by many enveloped viruses, including influenza viruses, herpes v

280 For enveloped viruses, such as the influenza A virus (IAV),

281 ssembly is complete, retroviruses, like most enveloped viruses, utilize host proteins to catalyze mem

282 e of the critical steps in the life cycle of enveloped viruses.

283 r their ability to mediate the entry of many enveloped viruses.

284 suggests potentially broad activity against enveloped viruses.

285 approach for vaccine design against diverse enveloped viruses.

286 for the ability to inhibit multiple diverse enveloped viruses.

287 ool to investigate the dynamics within these enveloped viruses.

288 ecretory pathway more commonly used by other enveloped viruses.

289 es representing components found in the cell envelope were treated with FNA at 6.09 mg N/L (NO(2)(-)

290 ype region and its boundaries to the nuclear envelope, where Amo1 mutants displayed milder phenotypes

291 ram-negative bacteria and their complex cell envelope, which comprises an outer membrane and an inner

292 multiprotein channels that span the nuclear envelope, which connects the nucleus to the cytoplasm.

293 This separation is achieved by the nuclear envelope, which controls the exchange of macromolecules

294 n and heterochromatin equally to the nuclear envelope will still preferentially locate heterochromati

295 is the HA that mediates fusion of the virus envelope with the membrane of the endosome(2).

296 g of additively manufactured titanium frames enveloped with CaP BioCer or titanium control implants w

297 loped viruses involves fusion of their lipid envelopes with cellular membranes to release the viral g

298 ng also showed that among some, but not all, envelopes with decreased neutralization sensitivity, V1

299 ortantly, we show that individuals harboring envelopes with higher likelihood of using CXCR4 or great

300 The transition between cell envelopes with one membrane (Gram-positive or monoderm)