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3 ce, "Origins of allergic disease: Microbial, epithelial and immune interactions" were to present and
7 , and barrier function and identify dietary, epithelial, and immune checkpoints along this axis to be
8 in western diet (WD)-induced loss of colonic epithelial barrier (CEB) function in mice with a genetic
10 C-BMP can measure ABCC1 activity at the lung epithelial barrier and may be applicable in humans to as
11 different approaches to diagnose and target epithelial barrier defects are currently being developed
13 mice with a genetic impairment in intestinal epithelial barrier function, junctional adhesion molecul
14 ting epithelial regeneration, which prolongs epithelial barrier impairment and creates an environment
16 [ABCC1]) is abundantly expressed at the lung epithelial barrier, where it may influence the pulmonary
18 nerating a conducive microenvironment on the epithelial boundary, which becomes further dysbiotic by
21 s. air) with a published data set from human epithelial brushes (smoker vs. non-smoker) revealed a hi
22 HOTAIR is a lncRNA overexpressed in several epithelial cancers and strongly correlated with invasion
27 d a gene and protein signature similar to an epithelial cell and gained chromatin accessibility sites
28 ST6Gal-I expression in blocking homeostatic epithelial cell apoptosis in gastric cancer pathogenesis
29 application initiates changes in intestinal epithelial cell characteristics relative to those of sta
30 uman intestinal enteroids (HIEs) are primary epithelial cell cultures that can provide insights into
32 in IL-13 biology to determine whether airway epithelial cell expression of 2 key mediators critical f
33 alignancy cascade, indicating that increased epithelial cell expression of ST6Gal-I is associated wit
35 chnique to measure the tension in individual epithelial cell junctions of cells in various locations
37 ed that hypothesis by infecting an oviductal epithelial cell line with C muridarum, followed by immun
40 report in Science that type III IFNs disrupt epithelial cell proliferation and differentiation in the
41 f macrophages in obese mice enhanced mammary epithelial cell stem/progenitor activity, elevated expre
43 gment epithelium (RPE) is a highly polarized epithelial cell type maintained at a senescence state, a
44 ution representation of the multiple mammary epithelial cell types in the organoids, and demonstrate
45 ron progenitor cells (NPCs) give rise to all epithelial cell types of the nephron, the filtering unit
47 mpare the role of myeloid- versus intestinal epithelial cell-derived IL-33 during dextran sodium sulf
48 treated HO-exposed mice and primary alveolar epithelial cells (AECs) with the novel TREK-1 activators
49 silico and in vitro using human endometrial epithelial cells (EEC) grown as monolayers or a 3-dimens
50 -culture on patient-derived human intestinal epithelial cells (HIECs), and incorporate perfused vascu
52 ells as a model, we observed that intestinal epithelial cells (IECs) were permissive to EV-A71 infect
53 not GT-I) invaded bovine and murine mammary epithelial cells (MECs) and induced apoptosis, as determ
54 e marrow chimeras, GILT expression in thymic epithelial cells (TECs), but not hematopoietic cells, wa
55 17 and miR-548b were upregulated in alveolar epithelial cells after CI/EVR, which merit further explo
56 is present in nasal, tracheal, and bronchial epithelial cells and constitutes a central element of th
58 it alters nutrient metabolism in intestinal epithelial cells and microbiome, leading to increased la
59 larity (PCP) pathway is required in alveolar epithelial cells and myofibroblasts for alveologenesis i
60 it enhances viral replication in human lung epithelial cells and primary human airway tissues by inc
63 tic and epigenetic alterations in colorectal epithelial cells but also affect the gut microbiota and
64 demonstrate viral tropism for choroid plexus epithelial cells but little to no infection of neurons o
65 R2) is strongly upregulated on renal tubular epithelial cells by acute cell-mediated rejection (ACR.
66 SCCs were distinguished from the surrounding epithelial cells by calretinin and phospholipase C140 im
67 vival factor for functionally differentiated epithelial cells by expressing a hyperactive STAT5 mutan
69 Here we review recent studies on how colon epithelial cells communicate directly with colon afferen
70 n of MNV receptor (CD300lf) in human HEK293T epithelial cells conferred susceptibility to MNV infecti
71 levels of ST6GAL-I and SOX9 in human gastric epithelial cells correlated positively with one another
72 pendent H33258 uptake was rarely observed in epithelial cells derived from the ectocervix and transfo
73 of selected Par proteins in blastomeres and epithelial cells during the embryogenesis of the ctenoph
77 elium to define transcriptomes of individual epithelial cells from healthy BALB/c mice (controls) and
78 -ATPase mRNA were determined in the cultured epithelial cells from lenses of the two types of mice.
80 ggest that promoting the survival of gastric epithelial cells has implications not only for H. pylori
84 chromatin remodeling machinery in intestinal epithelial cells in the colitis response and shows how a
85 ow two extragenic CREs that are prominent in epithelial cells in the lung, regulate expression of the
86 ifferentiation of the human prostate luminal epithelial cells induced by caAKT1 and c-Myc and reveals
88 splaying characteristic conversion of planar epithelial cells into multipolar and invasive mesenchyma
92 sion of miR-183 cluster in the human retinal epithelial cells leads to the reprogramming and transfor
95 at constitutive AKT activation in intestinal epithelial cells markedly enhances tumor invasion and me
97 activity was sharply increased in intestinal epithelial cells of microbiota-replete mice compared wit
101 hypothesized that Chlamydia-infected DCs and epithelial cells present overlapping sets of Chlamydia-M
102 w that ablation of HNF-1beta in mIMCD3 renal epithelial cells results in activation of beta-catenin a
106 emonstrate a novel mechanism by which cystic epithelial cells stimulate myofibroblasts in the pericys
107 estinal mucosa is lined by a single layer of epithelial cells that forms a tight barrier, separating
108 ed of a monolayer of diverse and specialized epithelial cells that perform functions ranging from nut
110 been shown to stimulate DNA damage in breast epithelial cells through mechanisms mediated by estrogen
111 n induced pluripotent stem cell-derived lung epithelial cells to model early-stage lung adenocarcinom
112 ge outlined here demonstrates the ability of epithelial cells to possess highly organized defense mac
113 , the cellular processes and contribution of epithelial cells to the host response are poorly underst
115 type and TP53 knockout human retinal pigment epithelial cells using a focused dual guide RNA library
116 econd, when Xist is conditionally deleted in epithelial cells using Keratin14-Cre or in B cells using
118 g to and subsequent infection of respiratory epithelial cells were increased upon preincubation of th
119 PBMCs from healthy donors and/or respiratory epithelial cells were stimulated with soluble antigens o
120 rticipants underwent bronchoscopy to collect epithelial cells whose DNA methylation was measured usin
121 el: the fusion was faster for spheroids from epithelial cells with lower apparent surface tension tha
122 c Pg-strains to invade human-retinal pigment epithelial cells(ARPE-19), their survival, intracellular
123 CE2 suggests tongue keratinocytes, olfactory epithelial cells, airway club cells and respiratory cili
125 (AKI) with adaptive proliferation of tubular epithelial cells, but repair can also lead to fibrosis a
126 herapeutically relevant cell types including epithelial cells, endothelial cells, B cells, T cells an
128 asthma pathophysiology, including on airway epithelial cells, mucus hypersecretion, and airway remod
129 lung microvascular endothelial and alveolar epithelial cells, we demonstrated that N-WASP downregula
130 tion factor TFIIH, in both B lymphocytes and epithelial cells, we hypothesized that SM utilizes XPB t
131 LT also promotes ETEC adhesion to intestinal epithelial cells, we postulated that increases in cAMP,
132 ss I and II molecules in endothelial but not epithelial cells, which exhibited constitutive expressio
133 cation, is found predominantly in intestinal epithelial cells, with chromogranin A-positive enteroend
156 n multiple environments - abscess formation; epithelial colonization; and cigarette smoke toxin expos
157 the cytotoxicity of so-obtained BRJ to human epithelial colorectal adenocarcinoma (Caco-2) and human
158 We now provide conclusive evidence that the epithelial component of pharyngeal teeth in zebrafish (t
163 cluded 18 patients with NK with a persistent epithelial defect or corneal ulcer, treated with topical
164 ry outcome measures included the size of the epithelial defect overlying the Intacs body, the intende
169 ice toward the development of severe corneal epithelial disease after exposure to a dry environment.
172 rt a causal role for ER stress and resulting epithelial dysfunction in PF and suggest ER stress as a
173 of a particular pattern of reticular bullous epithelial edema in a series of patients treated with ne
174 influenza severity by damaging the pulmonary epithelial-endothelial barrier and increasing pulmonary
175 = 0.79, P = .007) and an association between epithelial eosinophils and IL-5 concentrations in nasal
176 Enhancing the activity of TMEM16A increases epithelial fluid secretion and enhances mucus clearance
179 locks aberrant splicing in primary bronchial epithelial (hBE) cells from CF patients with the mutatio
182 pathway with key roles in organ development, epithelial homeostasis, tissue regeneration, wound heali
188 e to present and discuss potential microbial-epithelial-immune interactions underlying the early-life
191 otypes that can be linked to p120-catenin in epithelial integrity and turnover, and additional phenot
192 intestinal syndrome, spared gut function and epithelial integrity, and spared cell death in crypt bas
193 ance of the early life window for microbiota-epithelial interactions in the presence of inflammatory
195 ditional changes in aging, as glandular-like epithelial invaginations (GLEIs) derived from ABSCs emer
197 ributed to intrinsic differences between the epithelial lineages, we find that single cells of all li
199 pectedly, mRNA and protein expression of the epithelial marker E-cadherin either remained unaltered o
200 ures; these CTCs expressed proliferation and epithelial markers and correlated with poor clinical out
201 tissue types, specifically in regard to the epithelial mesenchymal transition (EMT) structural compo
203 lls to identify the key players establishing epithelial-mesenchymal cell plasticity during reversible
204 the known roles of ILF3 in immune response, epithelial-mesenchymal differential editing sites are en
205 ed as one of the key ECM markers in the lung epithelial-mesenchymal interface both at the RNA and pro
206 redict how factors known to promote a hybrid epithelial-mesenchymal phenotype can alter the phenotypi
207 survival, but also induced an AKT-dependent epithelial-mesenchymal transition (EMT) and beta-catenin
208 ecular pathways, both cytokines also induced epithelial-mesenchymal transition (EMT) in lung cancer c
209 engulfment, Schwann cell (SC) demyelination, epithelial-mesenchymal transition (EMT), loss of sensati
210 AKT in LAD cells, although unable to induce epithelial-mesenchymal transition (EMT), VAL exerts pote
212 rotein stimulates differential expression of epithelial-mesenchymal transition (EMT)-associated genes
217 regions, identifying E-box motifs common to epithelial-mesenchymal transition driver transcription f
218 22, phosphorylated STAT3, and markers of the epithelial-mesenchymal transition than nonneoplastic tis
221 ulations enriched with highly plastic hybrid epithelial/mesenchymal cells, which display invasive fea
222 ignaling pathway, as well as conservation of epithelial/mesenchymal cross talk in the intestine, has
223 n bacteria associated with a primary colonic epithelial monolayer in an in vitro human gut model syst
224 gy to enhance delivery across endothelial or epithelial monolayers is conjugation to cell-penetrating
226 bacteria having evolved traits to invade the epithelial mucus layer and reside deep within the intest
235 25 responses to neoadjuvant chemotherapy for epithelial ovarian cancer should not be used as individu
236 BRCA testing for all women with non-mucinous epithelial ovarian cancer, there is significant variabil
239 , acts as a guidance cue to orchestrate this epithelial pathfinding behavior, but how this signal is
240 rs and ordered micro-architecture induced an epithelial phenotype in CRC cells while disordered ECM d
242 s is implemented in a specialized way during epithelial polarization and that Aurora B has a role in
244 all cells in 2D cultures of a human bladder epithelial progenitor cell line in a dose-dependent mann
245 tified CD177 as a novel regulator of mammary epithelial proliferation and breast cancer pathogenesis
246 l infiltration into the ileum was increased; epithelial proliferation was decreased along with signif
247 observed in the bile duct, including ductal epithelial proliferation, micropapillary growth of bilia
250 g stem cells during infection and preventing epithelial regeneration, which prolongs epithelial barri
253 erapeutic approaches to restore the impaired epithelial repair mechanisms in COPD, which is still a h
255 its immunomodulatory actions, while abnormal epithelial repair responses may contribute to remodellin
256 function for the IL-33-ST2 axis in bronchial epithelial repair, and implicate ST2 in myeloid cell dif
258 both necessary and sufficient to induce the epithelial response, which is mediated by activation of
260 the regulation of cellular proliferation and epithelial restitution after intestinal epithelial injur
264 Here, we propose a mechanistic theory of epithelial shells which resemble small-organoid morpholo
266 etween acid-sensing ion channels (ASICs) and epithelial sodium channel (ENaCs), these channel familie
268 ultivation of limbal melanocytes with limbal epithelial stem/progenitor cells on fibrin hydrogels pre
270 porting the notion that events at the airway epithelial surface are critical for the development of t
271 lled from the discussions was that damage to epithelial surfaces lies at the origin of the various ma
272 lowing the generation of two opposing apical epithelial surfaces within the centre of an initially un
275 thin that environment, and indeed throughout epithelial tissues, cells experience competition with th
277 ation of T654 EGFR correlates with increased epithelial to mesenchymal, migration and invasion, and m
278 a stimulation downregulated SOX2 and induced epithelial-to-mesenchymal transdifferentiation accompani
282 ast cancer, increased ECM stiffness promotes epithelial-to-mesenchymal transition (EMT), cell invasio
286 population of progenitor cells that undergo epithelial-to-mesenchymal transition displaying characte
287 ed CD133-mediated cancer stemness and hybrid epithelial-to-mesenchymal transition features in advance
288 tory: initiated in basal cells exhibiting an epithelial-to-mesenchymal transition signature, tumorige
290 ic cells were used to evaluate the CSC, EMT (epithelial-to-mesenchymal transition), and metabolic pro
291 XCL11 significantly induced tumor migration, epithelial-to-mesenchymal transition, and matrix remodel
292 tes several key oncogenic processes, such as epithelial-to-mesenchymal transition, cellular migration
295 beta-depleted cells undergo a mesenchymal to epithelial transition (MET) and re-organise into acini-l
296 all protein is required to promote the early epithelial transmigration of human neutrophils into the
297 c spatial locations in which ~50 um-diameter epithelial tubules form by cell coalescence and structur
298 olangiocarcinoma (CCA) is a highly malignant epithelial tumor of the biliary tree with poor prognosis
299 small-cell lung cancer, mesothelioma, thymic epithelial tumours, and other pulmonary neuroendocrine n
300 -) and VDD significantly reduce both corneal epithelial wound healing and nerve density in diabetic m