ライフサイエンスコーパス: epithelium

1 to either prostate cancer or prostate normal epithelium.

2 which are also selected in human esophageal epithelium.

3 fection on the gut microbiome and on the gut epithelium.

4 ting photoreceptors from the retinal pigment epithelium.

5 f the targeted protein expression in corneal epithelium.

6 pitulate essential features of the pertinent epithelium.

7 introduction of different cell types into an epithelium.

8 n of neutrophils, using primary human airway epithelium.

9 1 and is not expressed in the normal mammary epithelium.

10 )/Clu(+) revSCs and could not regenerate the epithelium.

11 nvolved in the normal turnover of intestinal epithelium.

12 rturbed melanogenesis in the retinal pigment epithelium.

13 of the intestinal lumen from the intestinal epithelium.

14 essive migration and loss of retinal pigment epithelium.

15 estricted expression in the gastrointestinal epithelium.

16 ed from either endometrial or fallopian tube epithelium.

17 triggered by terminal differentiation of the epithelium.

18 n in periderm, frontonasal ectoderm and oral epithelium.

19 fects of Prevotella on the human endometrial epithelium.

20 ects ISCs and regeneration of the intestinal epithelium.

21 resented self-peptides by B cells and thymic epithelium.

22 asthma intervention by targeting the airway epithelium.

23 s to enhance the radiotoxicity of intestinal epithelium.

24 ough the periciliary fluid (PCF) bathing the epithelium.

25 nal progenitors to differentiated intestinal epithelium.

26 t larvae (Lgl) using the Drosophila follicle epithelium.

27 ome coronavirus 2 receptor ACE2 in bronchial epithelium.

28 es accumulation of fibrinogen within tubular epithelium.

29 ocate enteric bacteria across the intestinal epithelium.

30 ult epithelial progenitors to regenerate the epithelium.

31 F is expressed far from crypts in the villus epithelium.

32 ly dimorphic phenotype in the main olfactory epithelium.

33 s how selection operates in normal-appearing epithelium.

34 tain regenerative capacity of the intestinal epithelium.

35 r penetration or colonization of the colonic epithelium.

36 only specifically around the retinal pigment epithelium.

37 hroughput cancer driver discovery in mammary epithelium.

38 les and quantified in alveolar and bronchial epithelium.

39 s in IPF express molecular markers of airway epithelium.

40 icity of smoking effects on the human airway epithelium.

41 sease are present in both nasal and tracheal epithelium.

42 om the peptide prior to transport out of the epithelium.

43 phils, and 10 were replicated in respiratory epithelium.

44 cellular orientation within the plane of an epithelium.

45 nteraction with circPABPN1 in the intestinal epithelium.

46 ry that links the environment to the sensory epithelium.

47 iently orchestrate cell alignment in growing epithelium.

48 terial products through the small intestinal epithelium.

49 ospinal fluid produced by the choroid plexus epithelium.

50 ation resembling the stem cell of the airway epithelium.

51 to the lineage relationships of the prostate epithelium.

52 in a subset of luminal cells in the mammary epithelium.

53 ly infect ferret and human nasal respiratory epithelium.

54 of CCR1-expressing macrophages to the ductal epithelium.

55 lineage survival factor in prostate luminal epithelium.

56 observed at the protein level in the airway epithelium.

57 nd increased proliferation of the intestinal epithelium.

58 r a lifetime and is lined by a gland-forming epithelium(1,2).

59 ell layer but since teeth penetrate the oral epithelium, a modified barrier has evolved, called the j

60 In the acute stage, an absence of corneal epithelium, a scrambled appearance of the anterior strom

61 inity for bacteria than simulated intestinal epithelium, a valuable activity at therapeutic doses on

62 The intestinal epithelium acts as a barrier between the organism and it

63 s, endothelial cells, and in retinal pigment epithelium; agonism of PPARalpha with genetic or pharmac

64 -seq profiles from pediatric Crohn's disease epithelium alongside matched healthy controls to reveal

65 infused antibiotics to penetrate the bladder epithelium and accumulate to high enough levels to kill

66 epithelium and Bowman's layer measurements were performe

67 2 biomarkers were RPE65 for retinal pigment epithelium and CD163 for histiocytes, each tagged with d

68 of CD177 leads to hyperproliferative mammary epithelium and contributes to breast cancer pathogenesis

69 .5 to E13.5 but was expressed in both dental epithelium and dental papilla from E14.5 and persisted i

70 l hormone-dependent branching of the mammary epithelium and for proper alveologenesis during pregnanc

71 asthma is orchestrated by a disrupted airway epithelium and further perpetuated by a predisposed immu

72 insights into the biology of the intestinal epithelium and innate immune responses.

73 into how lineage-specific crosstalk between epithelium and neighboring mesenchymal cells underpin th

74 ic placode lineage, comprising the inner ear epithelium and neurons.

75 ning kidney organoids contain distal nephron epithelium and no ureteric epithelium, this distal nephr

76 apillaris, Bruch's membrane, retinal pigment epithelium and occasionally neurosensory retina.

77 tinct criteria: (1) complete retinal pigment epithelium and outer retinal atrophy (cRORA) and (2) hyp

78 is reprogrammed relative to normal prostate epithelium and particularly in cancers driven by oncogen

79 on cytoskeletal organization in Sertoli cell epithelium and pertinent Sertoli cell functions.

80 ith different chromogens, yellow for pigment epithelium and purple for CD163-positive (CD163(+)) mono

81 for cells (Xenopus oocyte), tissues (Xenopus epithelium and rat cornea), organs (Xenopus gills and mo

82 cell populations in both the normal prostate epithelium and RWPE1 cells and was frequently co-express

83 Here we use skin epithelium and skeletal muscle-among the most highly-str

84 on of significant differences of the corneal epithelium and the Bowman's layer in en face maps coveri

85 symbiotic microorganisms and the intestinal epithelium and the effective killing of penetrant microo

86 effect many of the diverse functions of the epithelium and the epithelium's interactions with H. pyl

87 Overexpression of IL-15 in both the epithelium and the lamina propria is required for the de

88 The interplay between pancreatic epithelium and the surrounding microenvironment is pivot

89 oordinated morphogenic crosstalk between the epithelium and vasculature, we introduce a 3D microfluid

90 hies primarily involving the retinal pigment epithelium), and H35.50 (unspecified macular degeneratio

91 fferentiate from stem cells in the olfactory epithelium, and how the epithelium generates cells with

92 ased the transmigration of virus through the epithelium, and treatment with an MMP inhibitor decrease

93 in the function of the gastrointestinal (GI) epithelium are critical for health and survival of multi

94 esponses to dsRNA in the human infant airway epithelium are regulated by p38-MAPK and NF-kB signallin

95 s, which function as chemosensors on the gut epithelium, are known to translate environmental cues in

96 s highlight the crucial role of the cervical epithelium as a barrier against ascending infection.

97 s have recently been reported in the wounded epithelium, as well as in the tumor, but within the woun

98 ated RIPK1 and MLKL expression in the airway epithelium at 8 to 10 days after infection, coinciding w

99 that Lrp6 was specifically expressed in the epithelium at E11.5 to E13.5 but was expressed in both d

100 Near the epithelium, B. fragilis upregulated numerous genes invol

101 utomatic segmentation of the retinal pigment epithelium/Bruch membrane complex.

102 of TMIGD1 significantly impaired intestinal epithelium brush border membrane, junctional polarity, a

103 eurons BAG and URX, which are not part of an epithelium but instead form membranous attachments to a

104 that is low or undetectable in healthy adult epithelium but upregulated in select injured tissues, in

105 TGR5 is expressed in the intestinal epithelium, but it is not clear how its activation affec

106 OY phytoplasmas entered the anterior midgut epithelium by seven days after acquisition start (daas),

107 occur as a consequence of DNA damage to the epithelium by UVR or chemical carcinogens.

108 er and increased colonization of the colonic epithelium by Wild-type EAEC than its isogenic Pic mutan

109 area between the peritrophic matrix and gut epithelium called the ectoperitrophic space.

110 The sensory epithelium called the organ of Corti separates the two f

111 ed macular degeneration, the retinal pigment epithelium can be damaged by light acting on photosensit

112 ses progenitor cell proliferation and dental epithelium cell differentiation.

113 (a measure of the number of retinal pigment epithelium cells exposed at the lesion border).

114 or-specific markers in human retinal pigment epitheliums cells.

115 y, supporting the concept that purely tumour epithelium-centric metrics of aggressiveness may be inco

116 tic levels of sunitinib in retinal pigmented epithelium/choroid and retina for more than six months.

117 system (retina, macula, and retinal pigment epithelium/choroid) reveals features of regulatory eleme

118 This cross-sectional study used nasal epithelium collected in 2015-2018 to compare expression

119 Its epithelium consists of several differentiated cell types

120 between tumor cells and the adjacent normal epithelium contributes to cancer progression, but its re

121 Since the intestinal epithelium contributes to innate immunity as a first lin

122 ive WST-11 mixed with dextran (WST-D) to the epithelium-debrided cornea and illumination with Near In

123 ), vessel tortuosity (2.5%), retinal pigment epithelium degeneration (2.5%), myelinated nerve fiber l

124 Retinal pigment epithelium degeneration followed by retinal and choroida

125 The epithelium degeneration was associated with a rapid loss

126 The lens epithelium-derived growth factor (LEDGF) is a cellular f

127 reflective foci (HRF), fibrovascular pigment epithelium detachment (fvPED), and serous PED (sPED).

128 with chronic CSCR and flat irregular pigment epithelium detachments (FIPEDs).

129 ding at different stages of auditory sensory epithelium development and find that Six1-binding to cis

130 SHP2 is involved in gastrointestinal (GI) epithelium development and homeostasis, but the underlyi

131 smokers; and 5) ACE2 is expressed in airway epithelium differentiated in vitro on air-liquid interfa

132 g more central neighbours to "telescope" the epithelium downwards into underlying mesenchyme.

133 retinal layers, such as the retinal pigment epithelium-drusen complex (RPEDC), were assessed by mult

134 ly impaired during differentiation of CRSwNP epithelium due to an altered expression of microRNAs.

135 lammation and damage to the gastrointestinal epithelium due to the production of potent toxins.

136 o the signaling crosstalk between stroma and epithelium during tissue regeneration and tumorigenesis.

137 their contribution was studied in intestinal epithelium dysfunction using coculture of primary endoth

138 Normal prostatic epithelium employs comparatively glycolytic metabolism t

139 human lung as well as human and murine skin epithelium, enabling epicutaneous vaccine delivery.

140 singly, the considered defects appear in the epithelium even when the number of cells in it is signif

141 f(A), f(B), and f(C) were correlated with f(epithelium), f(stroma), and f(lumen) (all P < .001), wit

142 rrelations between (f(A), f(B), f(C)) and (f(epithelium), f(stroma), f(lumen)), and the strength of c

143 liferation, micropapillary growth of biliary epithelium, focal bile duct stricture formation and bile

144 responses that are active in the intestinal epithelium following viral infection, but our understand

145 AR-6 and PKC-3 are required in the epidermal epithelium for animal growth, molting, and the proper pa

146 that must be established in the neighboring epithelium for apoptotic cells to be extruded.

147 ation of soluble drug in contact with ocular epithelium for as long as possible.

148 -quiescent supporting cells within a balance epithelium from adult mice.

149 results provide means of generating 3D tooth epithelium from adult SCs which can be utilized toward f

150 ith asthma and healthy controls in bronchial epithelium from biopsies (n = 27 versus n = 9) and brush

151 onic aggregates that restores a mucociliated epithelium from mesenchymal cells.

152 cell RNA-sequencing analysis of the tracheal epithelium from smokers and non-smokers, we generate a c

153 cts epithelial cells of the feather follicle epithelium from where it is shed into the environment.

154 rom the distinct metabolism of the prostatic epithelium from which it emerges.

155 uterus and a critical regulator of glandular epithelium (GE) differentiation, development, and functi

156 volatile fatty acid (VFA) dynamics and rumen epithelium gene expression associated with the transport

157 lls in the olfactory epithelium, and how the epithelium generates cells with many centrioles is not y

158 rve" stem cell populations in the intestinal epithelium has been debated since 1977.

159 Retinal pigmented epithelium has plentiful melanosomes, signifying a highl

160 bstruction, bioelectric defects in the nasal epithelium, histopathologic changes in the trachea, larg

161 In the corneal epithelium however, insulin selectively regulates PTEN-i

162 (SCAPE) microscopy of intact mouse olfactory epithelium, imaging ~10,000 olfactory sensory neurons in

163 e cellular heterogeneity of the human airway epithelium in 10 healthy living volunteers by single-cel

164 variable distance before the retinal pigment epithelium in 56.67% of eyes.

165 Manipulation of the epithelium in a mouse model of mammographic density supp

166 dent neutrophil recruitment across pulmonary epithelium in a pore-dependent fashion.

167 ic development and turnover of the olfactory epithelium in adult mice, and rosette-bearing cells ofte

168 well as OSN cell bodies within the olfactory epithelium in freely breathing mice, we find widespread

169 tinction between distal nephron and ureteric epithelium in human fetal kidney, we show here that, whi

170 9(+) ) is involved in the renewal of surface epithelium in injured EHBT.

171 ed in mast cells and localized near 15-LO(+) epithelium in NPs from patients with AERD.

172 e and composition of the airway and alveolar epithelium in regions of fibrosis.

173 transcriptional response in the endometrial epithelium in species with different implantation strate

174 Each vestibular sensory epithelium in the inner ear is divided morphologically a

175 tes transmigration of DCs across the vaginal epithelium in the mouse female reproductive tract (FRT).

176 tinued until there is an absence of columnar epithelium in the tubular esophagus on high-definition w

177 he gastric cardia (without residual columnar epithelium in the tubular esophagus) should not warrant

178 onization and infection of human respiratory epithelium in vitro We have now assessed whether Muribac

179 t secretion of miRNAs in EVs from the airway epithelium, in particular miR-34a, miR-92b, and miR-210,

180 onstrate broad effects of PPIs on esophageal epithelium, including their ability to curtail transcrip

181 atypia and proliferation, with multilayered epithelium, increased Ki67, PAX8 and Myc and decreased P

182 a (EPG) cells, arises in the ovarian surface epithelium, ingresses cortically by E12.5 or earlier, ex

183 er DMOG treatment associates with intestinal epithelium integrity and reduced damage caused by dimini

184 ability to study microbiome:human intestinal epithelium interactions in the laboratory.

185 However, sensory epithelium involvement in the cochlear blood flow regula

186 luripotent stem cell-derived retinal pigment epithelium (iPSC-RPE) to test the potential of gene augm

187 from a few malignant cells within an intact epithelium is a central, yet unanswered question.

188 The intestinal epithelium is a highly dynamic structure that rejuvenate

189 The choroid plexus (ChP) epithelium is a source of secreted signaling factors in

190 The mammalian lung epithelium is composed of a wide array of specialized ce

191 we show that collaboration with the alveolar epithelium is critical for controlling infection.

192 The mammary epithelium is indispensable for the continued survival o

193 othesized that reduction in c-Cbl in colonic epithelium is likely to increase the levels of nuclear b

194 The gut epithelium is populated by intraepithelial lymphocytes (

195 We show that VEGFA from the epithelium is required for a distinct endothelial cell (

196 If mucociliary clearance in the respiratory epithelium is severely impaired, the disorder is referre

197 The physical barrier function of the airway epithelium is tightly interwoven with its immunomodulato

198 Here, we report a stroma-epithelium ISLR-YAP signaling axis essential for stromal

199 d barrier has evolved, called the junctional epithelium (JE).

200 n with SARS-CoV-2 damages the choroid plexus epithelium, leading to leakage across this important bar

201 deletion of Smarcad1 in the mouse intestinal epithelium leads to colitis resistance and substantial c

202 n of light into the choroid, retinal pigment epithelium loss, and loss of outer retinal layers.

203 o the expression of ACE2 in the human airway epithelium.Methods: Airway epithelia sampled by fiberopt

204 Within the respiratory epithelium, more than one cell type expresses CFTR and t

205 d MERS CoVs predominantly infect respiratory epithelium, not macrophages.

206 Within this pseudostratified epithelium, nuclei synthesize DNA near the basal surface

207 giotensin-converting enzyme 2) on the airway epithelium.Objectives: The objective was to gain insight

208 ation followed by regeneration of normalized epithelium.Objectives: To evaluate the feasibility, safe

209 Pathological analysis of olfactory epithelium obtained from human COVID-19 autopsies reveal

210 propose that regeneration of a mucociliated epithelium occurs in response to biophysical cues sensed

211 ted with SARS-CoV-2 cell entry, in the nasal epithelium of children vs adults.

212 In the intestinal epithelium of Hnf4alphagamma(DKO) mice, expression level

213 re to produce three-dimensional maps for the epithelium of intact mouse lenses.

214 reased in both alveolar tissue and bronchial epithelium of patients with diabetes compared with contr

215 olecular chaperone BiP/GRP78 in conjunctival epithelium of patients with ocular cicatricial pemphigoi

216 s, and spermatozoa, which takes place in the epithelium of seminiferous tubules.

217 The epithelium of the lungs, gut, and skin, which operates a

218 lay in recovery and repair of the intestinal epithelium of up to 2 wk post the infection peak.

219 helial cross-linking remains inferior to the epithelium-off approach, although it is significantly sa

220 n, telomerase reactivation in the intestinal epithelium or pharmacological inhibition of ATM, YAP1, o

221 t reduction in cancer compared to non-cancer epithelium (p < 0.05, log(2) fold change range: -0.423 t

222 The barrier epithelium plays fundamental roles in immune defenses ag

223 nformation appears to occur in the olfactory epithelium prior to transmission of odor information to

224 responsible for mesenchymal growth, whereas epithelium-produced FGF9 and mesenchyme-produced FGF10 g

225 In asthma, bronchial epithelium protein expression of ST2 is decreased.

226 to propose that isotropic tension within an epithelium provides cells with a mechanically stable sub

227 ible ERBB2DeltaEx16 specifically in the lung epithelium rapidly developed lung adenocarcinomas follow

228 The epithelium regulates the absorption of nutrients, mounts

229 The newly formed epithelium remains relatively quiescent during the next

230 ion of the differentiation front by coupling epithelium remodeling at the tissue level with NSC fate

231 Neurogenesis in the zebrafish olfactory epithelium requires the bHLH proneural transcription fac

232 first line of defence, understanding how the epithelium responds to microbial and host stimuli is an

233 ining how the Drosophila pupal dorsal thorax epithelium responds to morphogenetic forces, we found th

234 The depletion of Rank in the mouse thymic epithelium results in reduced accumulation of natural T(

235 cover the entire endoderm-derived pharyngeal epithelium [Rosa et al., 2019, Sci.

236 t functions performed by the retinal pigment epithelium (RPE) and on oxygen and nutrients delivered b

237 ion), components of complete retinal pigment epithelium (RPE) and outer retinal atrophy (e.g., RPE pe

238 4(-/-) mouse model presented retinal pigment epithelium (RPE) and photoreceptor degeneration which wa

239 imaging and ocular history: retinal pigment epithelium (RPE) atrophy with treatment-naive quiescent

240 Retinal pigment epithelium (RPE) cells are cultured on top of custom-mad

241 l-domain OCT with respect to retinal pigment epithelium (RPE) in 836 spectral-domain OCT slices from

242 neural network in DR and the retinal pigment epithelium (RPE) in AMD.

243 The retinal pigment epithelium (RPE) is a highly polarized epithelial cell t

244 The retinal pigment epithelium (RPE) is a particularly vulnerable tissue to

245 Lipofuscin in the retinal pigment epithelium (RPE) is the major source of fundus autofluor

246 mmasome activation mainly in retinal pigment epithelium (RPE) or rather in non-RPE cells promotes CNV

247 d no adverse perturbation of retinal pigment epithelium (RPE) transcriptional programs in any model,

248 rreflective material (SHRM), retinal pigment epithelium (RPE), hyperreflective foci (HRF), fibrovascu

249 ) 1.3 Ca(2+) channels in the retinal pigment epithelium (RPE).

250 gulator of the ER-associated retinal pigment epithelium (RPE)65 isomerase necessary for recycling 11-

251 or zone, ellipsoid zone, and retinal pigment epithelium (RPE, P < 0.001 and P = 0.005-0.045, respecti

252 eparation of hyperreflective retinal pigment epithelium [RPE] from Bruch's membrane, with the gap bet

253 diverse functions of the epithelium and the epithelium's interactions with H. pylori The focal point

254 studies using optogenetic activation of the epithelium showed initiation of pain-like responses.

255 o efficiently cross healthy human intestinal epithelium (SMI-100) by a vesicular transcytosis process

256 ed alpha(v)beta(6) as a molecular target; an epithelium-specific cell surface receptor that is low or

257 Using epithelium-specific knockout mice of AC6, we demonstrate

258 ltured cells and in mouse models of prostate epithelium-specific mutant Pten/Kdm5b.

259 our understanding of the benefits of such an epithelium-specific response is incomplete.

260 tures, including organized luminal/glandular epithelium, stroma, vascularized mucosa and two-layered

261 escribe a role for ARID1A in the endometrial epithelium supporting early pregnancy establishment thro

262 genes for asthma are expressed in the airway epithelium, supporting the notion that events at the air

263 To better understand how the epithelium supports lens function, we have developed a n

264 In normal visual physiology, the pigment epithelium supports photoreceptors and participates in t

265 The epidermis, a multilayered epithelium, surrounds and protects the vertebrate body.

266 in the distal region of the Fallopian tube's epithelium (TE) before metastasizing to the ovary.

267 hly derived and rigorously patterned sensory epithelium that acts to convert auditory stimuli into ne

268 anical insults, a mono-layered or stratified epithelium that forms tight junctions and controls the s

269 olar capillaries are mosaics; similar to the epithelium that lines the alveolus, the alveolar endothe

270 ical use of cadherin on the basal side of an epithelium that may apply to vertebrate neurulation.

271 ressed in airway smooth muscle and bronchial epithelium that regulates the activity of G-protein-coup

272 The cochlear sensory epithelium, the organ of Corti, vibrates because of exte

273 the corneal defect by a hyporeflective thick epithelium, the persistence of the hyperreflective under

274 In the auditory sensory epithelium-the organ of Corti-progenitor cells exit the

275 o spindle cells and migrate along the midgut epithelium, thereby conveying endosymbionts to midgut si

276 in distal nephron epithelium and no ureteric epithelium, this distal nephron segment alone displays s

277 cell-fate switch from a transparent corneal epithelium to a keratinized, stratified squamous, psoria

278 equencing (scRNA-seq) data of gastric corpus epithelium to define transcriptomes of individual epithe

279 g two state transitions-from normal prostate epithelium to localized PCa to metastases-in specimens d

280 IL-1 induces the alveolar epithelium to produce granulocyte-macrophage colony-stim

281 e, appear to regulate the sensitivity of the epithelium to stressors and promote epithelial repair vi

282 hould be stated as measured from the corneal epithelium to the lens.

283 rucial molecule for the proper attachment of epithelium to tooth/implant surface.

284 The epithelium was fully healed after 6-8 days.

285 sted cytokines in the lamina propria and the epithelium was higher in CD patients than in the control

286 as loss of Lkb1 alone in the murine prostate epithelium was inconsequential for tumorigenesis, its co

287 aberrant as, after multiple infections, the epithelium was markedly thickened and bladder capacity w

288 on HIV-1 transmigration through endocervical epithelium, we demonstrated that CVF samples with greate

289 in vitro model of the differentiated airway epithelium, we found that the addition of physiological

290 haracteristics of the healthy human alveolar epithelium, we have developed a new method to immortalis

291 depleting actin-rich processes in the tumor epithelium, we provide evidence that signaling can be me

292 ial cells (VK2 E6/E7), modelling the vaginal epithelium were treated with either 4 nM 17beta-estradio

293 own unique molecular dialogue with the host epithelium, which ultimately converges on acquired pheno

294 ccompanied by increased disruption of airway epithelium, which was reversed by therapeutic blockade o

295 g mitochondrial bioenergetics in the colonic epithelium with 5-amino salicylic acid, a PPAR-gamma (pe

296 tes the initial apical infection of alveolar epithelium with SARS-CoV-2 by using induced pluripotent

297 I) usually provide a pseudostratified airway epithelium with similar abnormalities than original in v

298 SARS-CoV-2, is expressed in the human airway epithelium, with variations in expression relevant to th

299 l polarity within 5 hours and a mucociliated epithelium within 24 hours.

300 for differentiation of CD4(+) T cells at the epithelium, yet differentiated IELs are able to preserve