ライフサイエンスコーパス: erythroid progenitor cell

1 were also present in downstream myeloid and erythroid progenitor cells.

2 arly steps in the differentiation of myeloid-erythroid progenitor cells.

3 definitive erythropoiesis and maturation of erythroid progenitor cells.

4 elopmental potential of normal and malignant erythroid progenitor cells.

5 modimers signal to promote the maturation of erythroid progenitor cells.

6 mias are caused by a defect intrinsic to the erythroid progenitor cells.

7 otein activated by erythropoietin in primary erythroid progenitor cells.

8 liferation, and differentiation of mammalian erythroid progenitor cells.

9 enomic-scale description of gene activity in erythroid progenitor cells.

10 metarubricytes and other less differentiated erythroid progenitor cells.

11 nd -P in fetal liver and bone marrow-derived erythroid progenitor cells.

12 mulates proliferation and differentiation of erythroid progenitor cells.

13 be mediated by direct interaction of Tpo and erythroid progenitor cells.

14 globin genes during differentiation of adult erythroid progenitor cells.

15 liferation, differentiation, and survival of erythroid progenitor cells.

16 virus B19 shows remarkable tropism for human erythroid progenitor cells.

17 GATA1-mediated repression is deleterious to erythroid progenitor cells.

18 pression in K562, HUDEP-2, and primary human erythroid progenitor cells.

19 bgamma or Hbalpha in differentiating HiDEP-1 erythroid progenitor cells.

20 throid lineage, with expansion of SF3B1(mut) erythroid progenitor cells.

21 n in both K562 cells and primary human adult erythroid progenitor cells.

22 nd repressed their transcription in immature erythroid progenitor cells.

23 binding to erythropoietin receptor (Epor) on erythroid progenitor cells.

24 during B19V infection of permissive CD36(+) erythroid progenitor cells.

25 tress response in K562 cell line and primary erythroid progenitor cells.

26 19V) infection is highly restricted to human erythroid progenitor cells.

27 n of p21 and consequent cell cycle arrest in erythroid progenitor cells.

28 ins to promote the Epo-independent growth of erythroid progenitor cells.

29 or (SCF) stimulation in cultured human adult erythroid progenitor cells.

30 bin gene expression in primary CD71-positive erythroid progenitor cells.

31 tosis significantly during B19V infection of erythroid progenitor cells.

32 with RNA from wild-type and Eklf(-/-) early erythroid progenitor cells.

33 EKLF-dependent DNase I sensitivity in early erythroid progenitor cells.

34 while reducing the numbers of megakaryocyte-erythroid progenitor cells.

35 erminal proliferation and differentiation of erythroid progenitor cells.

36 B19 (B19V) has an extreme tropism for human erythroid progenitor cells.

37 -binding protein family that is expressed in erythroid progenitor cells.

38 nt for Epo-induced maturation of fetal liver erythroid progenitor cells.

39 vival, proliferation, and differentiation of erythroid progenitor cells.

40 the initial polyclonal expansion of infected erythroid progenitor cells.

41 vival, proliferation, and differentiation of erythroid progenitor cells.

42 control region and globin genes in ovary and erythroid progenitor cells.

43 nonuclear cells and that it was cytotoxic to erythroid progenitor cells.

44 ogenic human parvovirus B19 is restricted to erythroid progenitor cells.

45 red for B19V replication in ex vivo-expanded erythroid progenitor cells after initial virus entry and

46 Northern analysis of the erythroid progenitor cells again showed that beta2 but n

47 Expression of these receptors in primary erythroid progenitor cells also demonstrated a functiona

48 localized noncoding RNA that is expressed in erythroid progenitor cells and decreases during differen

49 hosphatase (PTP) activity in highly purified erythroid progenitor cells and found that the total PTP

50 und that depletion of hemogen in human CD34+ erythroid progenitor cells and HUDEP2 cells significantl

51 onomous B19V replication is limited to human erythroid progenitor cells and in a small number of eryt

52 B19 has a strong tropism to erythroid progenitor cells and is able to cause a series

53 nted in a significant subset of normal adult erythroid progenitor cells and may also be necessary for

54 Splenic erythroid progenitor cells and mesenchymal stromal cells

55 covered that DYRK3 is expressed primarily in erythroid progenitor cells and modulates late erythropoi

56 eq to study the interactome of EKLF in mouse erythroid progenitor cells and more differentiated eryth

57 2 led to the expansion of TGFbeta1-producing erythroid progenitor cells and promoted the expansion of

58 In accord with this, erythroid progenitor cells and reticulocytes were substa

59 DYRK3 is restricted to erythroid progenitor cells and testes.

60 or both proliferation and differentiation of erythroid progenitor cells and that the constraints on d

61 he antiapoptotic action of erythropoietin on erythroid progenitor cells and to be necessary for heme

62 inhibit proliferation and differentiation of erythroid progenitor cells and to produce apoptosis of e

63 with an anti-SK4 antibody, showed that human erythroid progenitor cells and, importantly, mature huma

64 zed in decreased amounts in the cytoplasm of erythroid progenitor cells, and appears to be susceptibl

65 9 therefore blocks proliferation of immature erythroid progenitor cells, and dexamethasone activates

66 SCF alone induced extensive proliferation of erythroid progenitor cells, and had a stronger synergist

67 erythropoietin and stem cell factor in human erythroid progenitor cells, and increased GSK3 activity,

68 rotein Bcl-x(L) is essential for survival of erythroid progenitor cells, and it increases substantial

69 e, we report that, in ex vivo-expanded human erythroid progenitor cells, B19V infection induces a bro

70 that EPO induces extensive proliferation of erythroid progenitor cells, but has no effect on the pro

71 Infection of erythroid progenitor cells by Friend spleen focus-formin

72 estoration of the cytosol oxidative state of erythroid progenitor cells by the pro-oxidant Paraquat r

73 cytosis) is a rare proliferative disorder of erythroid progenitor cells, characterized by elevated er

74 t form based on hyperplastic bone marrow and erythroid progenitor cell culture; these cases may subse

75 sed purified and synchronously growing human erythroid progenitor cells cultured for 7-14 days.

76 plastic bone marrow, vacuoles in myeloid and erythroid progenitor cells, cutaneous and pulmonary infl

77 trate that the 11 kDa protein contributes to erythroid progenitor cell death during B19V infection.

78 To test this hypothesis in erythroid progenitor cells derived from adult tissues, a

79 potential of the vector was demonstrated in erythroid progenitor cells derived from beta(IVS2-654)-t

80 rom purified and synchronously growing human erythroid progenitor cells, differentiating from erythro

81 of purified and synchronously growing human erythroid progenitor cells, differentiating from erythro

82 y protein induction during early human adult erythroid progenitor cell differentiation concomitant wi

83 PV erythroid progenitor cells display hypersensitivity to s

84 were cloned from human bone marrow and human erythroid progenitor cells: EEG-1L containing a 4350-nuc

85 Parvovirus B19 (B19V) infects human erythroid progenitor cells (EPCs) and causes several hem

86 eveloped an ex vivo-generated TP composed of erythroid progenitor cells (EPCs) and precursors cells.

87 Erythroid progenitor cells (EPCs) are deficient in mice

88 dvances in generating large numbers of human erythroid progenitor cells (EPCs) ex vivo from hematopoi

89 l role of erythropoietin (Epo) signaling, in erythroid progenitor cells (EPCs) expanded ex vivo from

90 19V) infection has a unique tropism to human erythroid progenitor cells (EPCs) in human bone marrow a

91 Using ex vivo-expanded primary human erythroid progenitor cells (EPCs) infected by B19V, we v

92 Using ex vivo-expanded primary human erythroid progenitor cells (EPCs) infected by B19V, we v

93 2 kinase complexes propagates signals within erythroid progenitor cells (EPCs) that are essential for

94 ythrotropic and preferentially replicates in erythroid progenitor cells (EPCs).

95 In erythroid progenitor cells, Epo stimulates induction of

96 eplication, however, is almost restricted to erythroid progenitor cells (ErPCs).

97 Promoter edited HUDEP-2 immortalized erythroid progenitor cells exhibit striking increases of

98 ion at physiological levels was confirmed in erythroid progenitor cells expanded ex vivo, and this EE

99 Erythroid progenitor cell expansion depends upon co-sign

100 ed, and B19V replication in ex vivo-expanded erythroid progenitor cells exposed to Epo (CD36(+)/Epo(+

101 In contrast, primary human erythroid progenitor cells express high levels of both P

102 In developmentally synchronized erythroid progenitor cells, expression peaked sharply fo

103 Friend virus infects erythroid progenitor cells, followed by an initial polyc

104 and excessive erythrocytosis is suggested by erythroid progenitor cells from a patient that exhibits

105 demonstrated in hematopoietic stem cells and erythroid progenitor cells from a patient with IVS2-745/

106 group, in which ex vivo production of human erythroid progenitor cells from CB was promoted by chrom

107 escence-activated cell sorting, the earliest erythroid progenitor cells from developing embryos for i

108 f Sf-Stk confers Friend virus sensitivity to erythroid progenitor cells from Fv2(rr) mice.

109 Furthermore, cultured erythroid progenitor cells from MAM-negative individuals

110 ion using ex vivo differentiation of CD34(+) erythroid progenitor cells from peripheral blood of heal

111 The majority of erythroid progenitor cells furthermore stained positivel

112 mma on SCF, EP, and IGF-I receptors of human erythroid progenitor cells has not been defined.

113 nduction during the rapid expansion of adult erythroid progenitor cells have not been fully elucidate

114 In normal erythroid progenitor cells, HCP may act to prevent prema

115 ly increased HbF production in human CD34(+) erythroid progenitor cells, HUDEP-2 cell lines, and tran

116 cks the proliferation and differentiation of erythroid progenitor cells in cultured human CD34(+) cel

117 /Gab2 complex mediates the growth of primary erythroid progenitor cells in response to Friend virus.O

118 Friend erythroleukemia and the expansion of erythroid progenitor cells in response to infection can

119 arrow cellularity and decreased frequency of erythroid progenitor cells in the bone marrow consistent

120 1 serves as the earliest marker of primitive erythroid progenitor cells in the embryonic day 7 (E7.0)

121 y, we investigated the levels of myeloid and erythroid progenitor cells in TPO-or c-mpl-deficient mic

122 in transfection of primary ex vivo-expanded erythroid progenitor cells, in comparison with apoptosis

123 rts iron-dependent differentiation of murine erythroid progenitor cells, indicating that the FeEnt co

124 s PlGF, and its enforced expression in human erythroid progenitor cells induces PlGF mRNA.

125 ocalized NS1 at the protein level in primary erythroid progenitor cells infected with B19V; and inhib

126 ols the proliferation and differentiation of erythroid progenitor cells into red blood cells.

127 The differentiation of committed erythroid progenitor cells involves other transcription

128 ivation-induced premature differentiation of erythroid progenitor cells is a molecular etiology to fo

129 n production is reduced and proliferation of erythroid progenitor cells is also impaired; this anaemi

130 The action of EPO on erythroid progenitor cells is well established, but its

131 Erythropoietin (EPO), a major regulator of erythroid progenitor cells, is essential for the surviva

132 rs the growth and differentiation program of erythroid progenitor cells, leading to malignant leukemi

133 vating the erythropoietin receptor (EPOR) in erythroid progenitor cells, leading to proliferation and

134 on in the proliferation of an SCF-responsive erythroid progenitor cell line and in the activation of

135 Utilizing an embryonic stem cell-derived erythroid progenitor cell line from mice deficient in GA

136 e-scale CRISPR knock-out screen in the human erythroid progenitor cell line HUDEP-2 and validate cand

137 ted kinases (ERKs) in HCD-57 cells, a murine erythroid progenitor cell line that requires EPO for sur

138 ere, we report the establishment of a murine erythroid progenitor cell line, iEBHX1S-4, developmental

139 Erythroid progenitor cell lines have been derived from c

140 Human erythroid progenitor cells lines have been produced from

141 and tumor-bearing mice, we demonstrate that erythroid progenitor cells lose their developmental pote

142 y that SATB1 family protein expressed in the erythroid progenitor cells may have a role in globin gen

143 increase 3-fold during maturation of murine erythroid progenitor cells, may help explain simultaneou

144 or (CMP) cells, as well as in megakaryocytic/erythroid progenitor cells (MEPs).

145 Using a state-of-the-art human erythroid progenitor cell model (HUDEP-2 and HEL cell li

146 Suppression of bone marrow myeloid and erythroid progenitor cells occurs after infection with a

147 B19 (B19V) takes place exclusively in human erythroid progenitor cells of bone marrow and fetal live

148 ovirus B19 (B19V) infection is restricted to erythroid progenitor cells of the human bone marrow.

149 Further in vitro analysis of the erythroid progenitor cells of this affected child reveal

150 ot be detected in RNA isolated from purified erythroid progenitor cells or from erythroid cells under

151 summary, we identified a new stress-specific erythroid progenitor cell population that links regenera

152 ockdown (KD) of PRMT1 by RNA interference in erythroid progenitor cells prevents histone acetylation,

153 actor (SCF) are essential growth factors for erythroid progenitor cell proliferation and differentiat

154 apacity to synergize with c-Kit in promoting erythroid progenitor cell proliferation.

155 he erythropoietin receptor on the surface of erythroid progenitor cells, promoting the differentiatio

156 .3 IU/L; P = .0077) and higher late to early erythroid progenitor cell ratio (10.44 v 4.48; P = .0106

157 pression of these microRNAs in primary human erythroid progenitor cells results in elevated fetal and

158 Loss of SOD2 in erythroid progenitor cells results in enhanced protein o

159 latelet c-mpl expression, in vitro assays of erythroid progenitor cells, serum erythropoietin levels,

160 gonists in stimulating self-renewal of early erythroid progenitor cells suggests that the clinically

161 Tumor-induced CD45(-)Ter119(+)CD71(+) erythroid progenitor cells, termed "Ter cells," promote

162 S proteins, and suggest that, in contrast to erythroid progenitor cells that employ Gab1 in PI3K sign

163 vitro culture system to expand human stress erythroid progenitor cells that express analogous cell-s

164 tipotent progenitor cells, and megakaryocyte-erythroid progenitor cells that is required under hemato

165 d an accumulation of nuclear p53 staining in erythroid progenitor cells that was not present in contr

166 nd identify a population of CD31+ short-term erythroid progenitors cells that confer protection from

167 ata1/GATA1 transcription in murine and human erythroid progenitor cells through an evolutionarily con

168 g erythroid tropism and drastically destroys erythroid progenitor cells, thus leading to most of the

169 ndition characterized by hypersensitivity of erythroid progenitor cells to EPO and low serum EPO (S-E

170 rythropoietin (EP) is required by late-stage erythroid progenitor cells to prevent apoptosis.

171 s by binding to its cell surface receptor on erythroid progenitor cells to stimulate erythrocyte prod

172 obin promoter directs v-Ha-ras expression in erythroid progenitor cells, ultimately leading to leukem

173 promoter elements were isolated from ELM-I-1 erythroid progenitor cells upon erythropoietin (epo) tre

174 Knockout of GATA2AS in human HUDEP2 erythroid progenitor cells using CRISPR-Cas9 genome edit

175 is an important regulator of iron update in erythroid progenitor cells via its control of Tfr1 trans

176 this fetal protein and growth, donated human erythroid progenitor cells were cultured in the presence

177 fferentiate precursor cells into myeloid and erythroid progenitor cells were not affected by HIV-1 in

178 Genes specific to erythroid progenitor cells were up-regulated by dexameth

179 s were markedly decreased in Eklf(-/-) early erythroid progenitor cells, which showed a delay in the

180 example, Myc stimulates the proliferation of erythroid progenitor cells, while the USF proteins and T

181 transgenic Eto2 null mice and in human CD34+ erythroid progenitor cells with reduced ETO2, loss of ET

182 ed both K562 erythroleukemic cells and human erythroid progenitor cells with S-nitrosocysteine (CysNO

183 IE is an abnormal expansion of the number of erythroid progenitor cells with unproductive synthesis o

184 lentiviral short hairpin RNA transduction of erythroid progenitor cells, with global surface proteomi