ライフサイエンスコーパス: essential amino acid

1 pplementation even though glutamine is a non-essential amino acid.

2 Tryptophan is an essential amino acid.

3 sing the abundance of methionine, a limiting essential amino acid.

4 indicated that PhtA transports threonine, an essential amino acid.

5 uptake and plasma concentrations of all the essential amino acids.

6 ty leads to changes in the metabolism of non-essential amino acids.

7 ic non-protein amino acids and the levels of essential amino acids.

8 c and APIp exhibited high content of all the essential amino acids.

9 CPHs had similar and adequate quantities of essential amino acids.

10 e, which identified Pro, Leu, and Cys as the essential amino acids.

11 especially Threonine and Tryptophan than non essential amino acids.

12 incipal source of nutrition, particularly of essential amino acids.

13 unexpected new roles, functional domains and essential amino acids.

14 urposes of the host, namely the synthesis of essential amino acids.

15 in of mice restricts intake of diets lacking essential amino acids.

16 edominant cellular pathway for the uptake of essential amino acids.

17 and phenylalanine being the most affected of essential amino acids.

18 retains capabilities for biosynthesis of all essential amino acids.

19 l cycle protein expression in the absence of essential amino acids.

20 ut had no effect on those of the majority of essential amino acids.

21 o increase majority of the essential and non-essential amino acids.

22 Amino acid profiling showed good amount of essential amino acids.

23 lism such as low alanine levels and elevated essential amino acids.

24 Surprisingly, PDAC accumulated essential amino acids.

25 al supplementation with whey protein (22 g), essential amino acids (10.9 g, including 4 g leucine), a

26 All portions contained a large amount of essential amino acids (167.66-187.63 mg/g sample), in wh

27 kg(-1) . d(-1) and 6.77 g of a mixture of 5 essential amino acids 3 times/d (leucine, isoleucine, va

28 ti protein content (12.3 to 23.4%) and total essential amino acids (3.76 to 7.59%) increased with add

29 (48%), essential fatty acids (23-100%), and essential amino acids (34-67%) available for human consu

30 s contained measurable quantities of 9 of 10 essential amino acids (41.62-63.50% of the total amino a

31 otein hydrolysate contained a high amount of essential amino acids (48.22%) and had arginine and lysi

32 amino acid content was 91.90+/-7.70% mainly essential amino acids (55.87+/-2.15mgg(-1)) which were c

33 Furthermore, nutrient quality expressed as essential amino acid (72.3-77.1), thrombogenicity (1.22-

34 rter often required for tumor cell import of essential amino acids (AA) including Methionine (Met).

35 high relative abundance of essential and non-essential amino acids (AAs).

36 WJP of C-306 grown using CNS had abundant essential amino acids (AAs).

37 ized by simultaneous glutamine depletion and essential amino acid accumulation.

38 We previously showed that free-form essential amino acids acutely stimulate muscle protein s

39 mutations in gene 2.5 uncovered a variety of essential amino acids, among which was a single amino ac

40 Leucine, as an essential amino acid and activator of mTOR (mammalian ta

41 l-Methionine is an essential amino acid and is required for protein synthes

42 e essential amino acids, and a conditionally essential amino acid and its precursor.

43 owards L-phenylalanine, as a kind of typical essential amino acid and phenylketonuria biomarker was d

44 ource of protein with high levels of several essential amino acids and a good nutritional value.

45 ls overcome their dependence on supplemented essential amino acids and can be selectively labeled thr

46 and can theoretically provide S. strix with essential amino acids and cofactors, which the protist c

47 results in increased intracellular levels of essential amino acids and enhanced mTORC1 signalling, pr

48 the latter could benefit from a supply with essential amino acids and important cofactors.

49 ls grow indefinitely in media lacking single essential amino acids and replicate once in the absence

50 Both the supply of essential amino acids and the bioactivities of milk prot

51 a genetic program for the cellular uptake of essential amino acids and the synthesis of nonessential

52 ts are proline, chlorophyll A and B, all the essential amino acids and vitamin A, E and C.

53 e feeding on an impoverished diet lacking in essential amino acids and vitamins.

54 tivates the UPS and autophagy, which provide essential amino acids and, together with the enhanced ub

55 ing of specific nutrients (e.g., B vitamins, essential amino acids) and modulation of the insect nutr

56 such as pyridoxine/vitamin B6, taurine, some essential amino acids, and a conditionally essential ami

57 13%, lowered fetal plasma concentrations of essential amino acids, and decreased the phosphorylation

58 nolamine lipid structures, essential and non-essential amino acids, and metabolites involved in polya

59 Supplementation with whey protein, essential amino acids, and vitamin D, in conjunction wit

60 vidence is insufficient to determine whether essential amino acids are affected by varying gluconeoge

61 transcription factor DNA-binding sites, and essential amino acids are revealed by the nucleotide fle

62 In aphids, the 10 essential amino acids are scarce in the phloem sap diet

63 act in the M. sexta midgut to catabolize the essential amino acids Arg and Thr, respectively.

64 ition model in which the accumulation of the essential amino acid arginine in A. pisum hemolymph redu

65 Transport of the essential amino acids arginine and lysine is critical fo

66 Cat-1, the transporter for the essential amino acids, arginine and lysine, is one of th

67 Cat-1, is a high affinity transporter of the essential amino acids, arginine and lysine.

68 oteobacteria), can produce the remaining two essential amino acids as well as many vitamins.

69 As a proof of concept, eighteen essential amino acids at physiological concentrations we

70 buting to nutrition, especially by providing essential amino acids, B vitamins, and, for fungal partn

71 ed antimicrobials based on dual targeting of essential amino acid biogenesis and its linkage to cell

72 lic processes promoting colonization include essential amino acid biosynthesis and iron acquisition p

73 ene sets conferring similar capabilities for essential amino acid biosynthesis, in both cases precise

74 ugh Buchnera's genome encodes most genes for essential amino acid biosynthesis, several genes in esse

75 Supplementation with essential amino acids blunts the fructose-induced increa

76 We hypothesized that protein, essential amino acid, branched-chain amino acid, and leu

77 Neither essential amino acids, branched-chain amino acids, nor a

78 Nutrient deprivation based on the loss of essential amino acids by catabolic enzymes in the microe

79 ork has focused on identifying catalytically essential amino acids by mutagenesis of Bacillus megater

80 The gonads were rich in essential amino acids (ca. 32.1% of total amino acids) w

81 igner protein-deprived diet enriched in free essential amino acids can 1) promote the brown fat therm

82 Nutrition' group ingested a leucine-enriched essential amino acid-carbohydrate mixture (EAC).

83 he functionality of PR without affecting the essential amino acid composition.

84 p between the fold increase in MPS and blood essential amino acid concentration ([EAA], mM) was hyper

85 Prosopis alba proteins, are not deficient in essential amino acids considering the amount of amino ac

86 Defatting and extended DoM both improved the essential amino acid content in RB.

87 Similarly, essential amino acid content was also higher in placenta

88 a have been established in relation to their essential amino acid contents, protein richness, digesti

89 trongly reduced the lysosomal efflux of most essential amino acids, converting the lysosome into a ce

90 We predict that nonessential and essential amino acids correspond to these nutrient class

91 suggest that intermittent deprivation of an essential amino acid could allow dose reduction of cispl

92 Depriving cells of a single essential amino acid decreased PRPP synthetase activity

93 In aphids, the supply of essential amino acids depends on an ancient nutritional

94 roxide dismutase expression mediated through essential amino acid depletion concurrent with an increa

95 However, essential amino acids derive only from the larval diet,

96 (Bacteroidetes), can produce eight of the 10 essential amino acids, despite having a genome of only 2

97 Arginine is considered an essential amino acid during critical illness in children

98 of transceptor for sensing and transporting essential amino acids during mosquito reproduction.

99 nhance the muscle protein anabolic effect of essential amino acid (EAA) + sucrose intake in older sub

100 The essential amino acid (EAA) density of a food also emerge

101 fusion in the postabsorptive state and after essential amino acid (EAA) ingestion on three occasions:

102 The effects of essential amino acid (EAA) supplementation during modera

103 pecifically activated by deficiencies in any essential amino acid (EAA); EAA deficiency leads to rapi

104 and valine (59.2-61.8) are the most abundant essential amino acids (EAA) (mg/g protein).

105 The essential amino acids (EAA) and total amino acids (TAA)

106 AF contained all the essential amino acids (EAA) except lysine and threonine,

107 s subsequent rapid efflux in the presence of essential amino acids (EAA) is the rate-limiting step th

108 synthesis represented as a function of five essential amino acids (EAA).

109 ry insufficiencies of macronutrients such as essential amino acids (EAA).

110 hen compared with MODL and higher content of essential amino acids (EAAs) (488.6-402.9 mg/g of protei

111 Essential amino acids (EAAs) are key factors in determin

112 Dietary protein provides essential amino acids (EAAs) for the synthesis of new pr

113 Essential amino acids (EAAs) have been shown to attenuat

114 Restricting availability of essential amino acids (EAAs) limits aminoacylation of tR

115 is affected by the presence of the remaining essential amino acids (EAAs).

116 of enzymes that consume at least 5 different essential amino acids (EAAs).

117 cle proteins after a bolus ingestion of 15 g essential amino acids (EAAs).

118 Lysine, a nutritionally essential amino acid, enters the oral cavity in gingival

119 analysis revealed a higher concentration of essential amino acids especially Threonine and Tryptopha

120 letion (TD) induced by oral loading with all essential amino acids except the serotonin precursor try

121 (14.5%) and encompassed adequate amounts of essential amino acids, fatty acids and minerals.

122 Cysteine is an essential amino acid for B. pertussis and must be presen

123 This enzyme decarboxylates lysine, an essential amino acid for dentally attached cell turnover

124 l-Methionine (Met) is an essential amino acid for humans and is important for pro

125 alism in which each yeast strain supplies an essential amino acid for its partner strain.

126 ps such as rice, as methionine is a limiting essential amino acid for mammalian diets.

127 l-tryptophan (Trp), an essential amino acid for mammals, is the precursor of a

128 Arginine is an essential amino acid for normal T-cell function whose av

129 eucine (an activator of mTOR), glutamine (an essential amino acid for nucleotide biosynthesis and sub

130 Cysteine is an essential amino acid for T-cell activation because T cel

131 strate for glutaminolysis), and arginine (an essential amino acid for tumor cells), suggesting that E

132 lant-based proteins can provide the required essential amino acids for health, animal proteins genera

133 crucial for human health because it provides essential amino acids for protein synthesis.

134 Essential amino acids for this catalytic activity were i

135 on of Slif are consistent with conveyance of essential amino acids from gut to fat body.

136 hich auxotrophic genotypes of E. coli derive essential amino acids from prototrophic donor cells usin

137 ritional and bioactive components, including essential amino acids, functional lipids, dietary fibre,

138 se of the cell cycle that are dependent upon essential amino acids, Gln, and finally, a checkpoint me

139 Dividing cells rely on the "conditionally essential" amino acid glutamine (Q) as an anaplerotic ca

140 ate, cancer cells rely on the 'conditionally essential' amino acid glutamine (Q) as an anaplerotic ca

141 The non-essential amino acid, glutamine, exerts pleiotropic effe

142 Furthermore, in HCT116 cells two non-essential amino acids, glutamine and serine, which are o

143 o acids: threonine, arginine and lysine; non-essential amino acids: glycine and homocysteine; and sol

144 Auxotrophic for 8 of the 10 essential amino acids, H. defensa is reliant upon the es

145 Specifically, bacterial provisioning of essential amino acids has been demonstrated.

146 an interaction between methionine and other essential amino acids having a key role.

147 Its proteins are a good source of essential amino acids; however, there are no reports on

148 ntinuous supply of all of the indispensable (essential) amino acids (IAAs).

149 onessential amino acids Gly and Glu, and the essential amino acid Ile were more abundant in the scalp

150 Arginine, a semiessential or conditionally essential amino acid in humans, is one of the most metab

151 Methionine is an essential amino acid in mammals at the junction of methy

152 equate provision of glycine, a conditionally essential amino acid in pregnancy, may play a role in th

153 Taurine is an essential amino acid in some mammals and is conditionall

154 se activity with maribavir or mutation of an essential amino acid in the kinase abolished its ability

155 This approach to identifying essential amino acids in a protein of interest introduce

156 thways associated with the production of non-essential amino acids in Haemophilus influenzae were com

157 in amino acids (BCAAs) are three of the nine essential amino acids in human and animal diets and are

158 activity is required for the biosynthesis of essential amino acids in plants and microorganisms.

159 red for the biosynthesis of one fifth of the essential amino acids in plants and microorganisms.

160 of IUGR, we found reduced concentrations of essential amino acids in the experimental dams.

161 porter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates

162 the epithelial uptake and redistribution of essential amino acids including precursors of several ne

163 c1-dependent macropinocytosis to provide non-essential amino acids, including asparagine.

164 RNA cleavage is inhibited in the presence of essential amino acids, independent of the persistence of

165 Overloading the medium with non-essential amino acids induced apoptosis, but essential a

166 Limiting any essential amino acid initiates this signaling cascade, w

167 atomic model for each map and identified an essential amino acid involved in genome encapsidation.

168 defined medium where the only source of the essential amino acid isoleucine was from peptides of var

169 AT2) is an inducible transporter of the semi-essential amino acid L-arginine (L-Arg), which has been

170 The product of the reaction is the essential amino acid l-lysine, which is an important pre

171 colonic motility; a prolific producer of the essential amino acid L-Phe, which we identified as an ag

172 Since depletion of the essential amino acid L-tryptophan (Trp) affects immune r

173 Since depletion of the essential amino acid L-tryptophan (Trp) severely affects

174 two important heme proteins that degrade the essential amino acid, l-tryptophan (Trp), along the kynu

175 We show that withdrawal of essential amino acids leads to an increase in cytosolic

176 ) is a key enzyme in the biosynthesis of the essential amino acid leucine, and thus primary metabolis

177 lular albumin was the obligate source of the essential amino acid leucine.

178 On the other hand, essential amino acids (leucine in particular) and insuli

179 Five essential amino acids (leucine, lysine, methionine, thre

180 Essential amino acid levels in all insect species were c

181 ted arginine deiminase (ADI-PEG 20) depletes essential amino acid levels in argininosuccinate synthet

182 Essential amino acid levels of the gastrocnemius muscle

183 Essential amino acids like lysine and tryptophan are def

184 tural source of antioxidant insoluble fibre, essential amino acids, low glycaemic sugars, resistant t

185 retrovirus as a membrane transporter for the essential amino acids lysine and arginine was a landmark

186 e gene (CGS), to improve the contents of the essential amino acids lysine and methionine.

187 onutrients (provitamin A and folates) and an essential amino acid (lysine) in three major cereal grai

188 ured the generation of higher levels of free essential amino acids; lysine, phenylalanine and arginin

189 sociated genetic variants, whereas decreased essential amino acids may point to nutritional deficienc

190 The essential amino acid methionine can be used for protein

191 dictor of maternal tHcy (P < 0.001) when the essential amino acid methionine was low.

192 Here we show that dietary restriction of the essential amino acid methionine-the reduction of which h

193 alamin biosynthetic capabilities to make the essential amino acid methionine.

194 In an attempt to increase the content in essential amino acids methionine and tryptophan of the t

195 modeled have lost biosynthetic pathways for essential amino acids methionine, tryptophan, or leucine

196 An essential amino acid motif (DGXD) containing aspartate r

197 Essential amino acid muscle loss was also significantly

198 in the diet can affect the oxidation of some essential amino acids, namely leucine.

199 anges suggests an autonomous increase of non-essential amino acids (NEAA) in muscle and treatment of

200 Arginine is an essential amino acid necessary for protein synthesis and

201 ells called bacteriocytes, where it produces essential amino acids needed by hosts.

202 about 10% is devoted to the biosynthesis of essential amino acids needed by its hosts.

203 ivation to the release from lysosomes of the essential amino acids needed to drive cell growth.

204 We utilized this finding to identify the essential amino acids of EF-Tu(Mp) that mediate Fn inter

205 ics of fully deuterated Val80 and Val84, two essential amino acids of the dimerization motif.

206 protein were still uncertain, and those for essential amino acids or essential fatty acids were unkn

207 t, in an arginine-regulated fashion, of many essential amino acids out of lysosomes, including leucin

208 wed a synchronous and homogenous pattern for essential amino acids over time in the hepatic portal ve

209 essential amino acids induced apoptosis, but essential amino acid overloading partially ameliorated a

210 Then, essential amino acid pathways are lost (at ~30-60 mya),

211 al amino acid biosynthesis, several genes in essential amino acid pathways are missing, as are most g

212 trient production between symbionts, several essential amino acid pathways in the mealybug assemblage

213 -regulated genes fill the gaps of Buchnera's essential amino acid pathways.

214 ignificantly decreased concentrations of the essential amino acid phenylalanine and the essential bra

215 ynthesis, which spans diverse metabolisms of essential amino acids, phenylpropanoids, benzenoids, and

216 nning mutations identified important but not essential amino acid positions.

217 The addition of essential amino acids potentiates the synthetic response

218 growth advantage to the bacterium, providing essential amino acid precursors by initiating the degrad

219 amino acids, H. defensa is reliant upon the essential amino acids produced by Buchnera.

220 high protein content (62.0 +/- 6.3%) and an essential amino acid profile comparable to MP from ammon

221 s fraction (AF) obtained by EAE had a better essential amino acid profile than the residues obtained

222 rnitine, spermidine, and the total amount of essential amino acids, provided significant prognostic v

223 previously that depriving cells of a single essential amino acid rapidly and reversibly arrests puri

224 The essential to non-essential amino acid ratio was 0.5.

225 L-Tryptophan is an essential amino acid required for protein synthesis.

226 The branched-chain amino acids (BCAA) are essential amino acids required for protein homeostasis,

227 acid studies with the goal of assessing the essential amino acid requirements for egg production.

228 The essential amino acid requirements of formula-fed infants

229 accessibility of the nearby cysteine 67, an essential amino acid residue for the formation of HLA-B2

230 All essential amino acid residues for substrate binding foun

231 Identification of essential amino acid residues of these proteases suggest

232 It also provides information on the essential amino acid residues that determine donor subst

233 of this transporter have been identified as essential amino acid residues that probably function as

234 Together, these data demonstrate that two essential amino acid residues within a four-amino acid s

235 In summary, we have identified three essential amino acid residues within the N-terminal regi

236 Among these essential amino acid residues, we find that residues Arg

237 the reaction intermediates and catalytically essential amino acid residues.

238 nd to be the most abundant essential and non-essential amino acids, respectively.

239 fication of Leu(480) and Gln(481) as the two essential amino acids responsible for the enhanced activ

240 d brain leucine accumulation displaces other essential amino acids resulting in neurotransmitter depl

241 The non-essential amino acids serine and glycine are used in mul

242 mportant because serum concentrations of the essential amino acids should not be lower than those in

243 rotein macropinocytosis can also serve as an essential amino acid source.

244 Here we link essential amino acid starvation and Ca(2+) in a signalin

245 an intravenously administered mixture of 10 essential amino acids stimulated insulin secretion.

246 Vps34 activity is stimulated by an influx of essential amino acids such as leucine and this may prolo

247 PBPI was found to obtain high amount of essential amino acids such as leucine, lysine, and pheny

248 profile of PFCP showed a high percentage of essential amino acids, such as arginine, lysine, histidi

249 We report here that limitation of essential amino acids, such as methionine and cysteine,

250 e mineral elements, such as K, Ca and P, and essential amino acids, such as tryptophan, valine, and t

251 of this study was to evaluate the effect of essential amino acid supplementation on the increase in

252 inhibitor 3-methyladenine was alleviated by essential amino acid supplementation.

253 How immune cells integrate information about essential amino acid supplies and then transfer these si

254 In contrast, protein catabolism and essential amino acid synthesis pathways in baleen whale

255 The essential amino acid taurine has important physiologic a

256 e that supplementation with L-methionine, an essential amino acid that assists in the metabolism of h

257 Glutamine is a conditionally essential amino acid that continues to function at very

258 Tryptophan is an essential amino acid that is required for normal develop

259 Methionine was the only essential amino acid that rapidly induced PGC-1alpha ace

260 inhibited by the depletion of methionine, an essential amino acid that serves as the direct substrate

261 hids and Buchnera aphidicola, which produces essential amino acids that are rare in the phloem sap di

262 uided mutagenesis of Msl5 distinguished four essential amino acids that contact the BP sequence from

263 oretic profile, showing a suitable amount of essential amino acids that covers the recommended daily

264 ids (BCAAs) Leu, Ile, and Val are among nine essential amino acids that must be obtained from the die

265 s (BCAAs) valine, leucine and isoleucine are essential amino acids that play critical roles in animal

266 Because tryptophan is an essential amino acid, these findings suggest that a phys

267 plants had increased concentrations of free essential amino acids: threonine, arginine and lysine; n

268 The ratio of Essential amino acid to total amino acid and predicted p

269 re elevated importation of essential and non-essential amino acids to generate large numbers of daugh

270 Adding essential amino acids to the dietary restriction conditi

271 ne were the least abundant essential and non-essential amino acids to with 0.23 g methionine and 0.36

272 We sought to investigate the role of the essential amino acid transporter L-type amino acid trans

273 By catabolizing the essential amino acid TRP, cells expressing the enzyme in

274 its T-cell proliferation by catabolizing the essential amino acid tryptophan (Trp) into the kynurenin

275 oxygenase (IDO) catalyses degradation of the essential amino acid tryptophan into immunomodulatory me

276 It has been proposed that the essential amino acid tryptophan is catabolized in the tu

277 Local catabolism of the essential amino acid tryptophan is considered an importa

278 In mammalian cells, the essential amino acid tryptophan is degraded primarily by

279 malarial drug quinine perturbs uptake of the essential amino acid tryptophan, and patients with low p

280 derived from gut bacterial metabolism of the essential amino acid tryptophan, in regulating intestina

281 ough melatonin is a direct derivative of the essential amino acid tryptophan, little is known about t

282 ase (IDO), which depletes local pools of the essential amino acid tryptophan, resulting in blockade o

283 Here, we report that omission of a single essential amino acid - tryptophan - from the diet abroga

284 The essential amino acids: tryptophan, isoleucine, valine, p

285 , lysine, histidine, methionine, and the non-essential amino acids: tyrosine, 4-hyrdroxy proline, arg

286 We examined 20 essential and non-essential amino acids using the ORAC assay and used a si

287 Here we report that the essential amino acid valine is indispensable for the pro

288 Contents of essential and non-essential amino acids varied in the range of 22.8-42.3 a

289 ntly, Blattabacterium can produce all of the essential amino acids, various vitamins, and other requi

290 of total free amino acids, essential and non-essential amino acids were 199.65 mg/100 g, 113.69 mg/10

291 alanine) were present and the most abundant essential amino acids were arginine, leucine, lysine and

292 ular concentrations of essential but not non-essential amino acids were decreased by bafilomycin in E

293 The average concentrations of protein and essential amino acids were higher in the muscle than in

294 All essential amino acids were present in the free form, exc

295 rates, fat mass, fat-free mass, and several essential amino acids were significantly higher in both

296 The most abundant essential amino acids were Thr (5.7%), Val (6.0%), Ile (

297 s depends on intracellular concentrations of essential amino acids, which are maintained by a specifi

298 precursor of SAMe is methionine, one of the essential amino acids, which is activated by SAMe-synthe

299 Histidine is an essential amino acid with health benefits that may warra

300 oles of these enzymes in the biosynthesis of essential amino acids within the plastid.