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1 patients with CRC-LM is neither feasible nor ethical.
5 tient with incurable cancer and conducted an ethical analysis incorporating (1) evidence from both We
6 - with the aim of highlighting the need for ethical analysis of specific issues, as well as for the
12 , and protections traditionally used to make ethical and evidence-based decisions about new technolog
14 lts to study subjects/participants generates ethical and legal challenges for laboratories performing
15 effectiveness of deceased donor program) and ethical and legal considerations (eg, regarding living d
16 s should act on collegial concern as well as ethical and legal guidelines that require reporting of b
17 ions, necessitating careful consideration of ethical and legal implications for privacy in genomic da
20 ments do not reflect compliance with current ethical and legal requirements that govern research with
21 ld be further explored and incorporated into ethical and legal research guidance to increase adolesce
22 important tools in diabetes research because ethical and logistical constraints limit access to human
24 perspective reviews the debate around these ethical and moral dilemmas more broadly but focuses spec
25 The surging COVID-19 pandemic has raised ethical and moral dilemmas that Western nations with fir
26 n and interception of disease embedded in an ethical and patient-centred vision will be achieved thro
27 us (HIV) cure-related research, a persistent ethical and practical challenge surrounds the use of ana
28 PATC3H researchers were asked to identify ethical and practical challenges of adolescent consent t
29 Herein, we examine a few basic, necessary ethical and practical concerns relevant to this indicati
32 rs to their implementation, including legal, ethical and privacy barriers, as well as organizational
33 Research was formed to identify and address ethical and regulatory challenges associated with the re
35 cientific community to address long-standing ethical and scientific barriers to equitable representat
37 research should conform to high standards of ethical and scientific integrity, given that human lives
40 lso provides guidance on how to approach the ethical and social issues that will likely arise when th
42 earning during undergraduate research, makes ethical and societal impacts of science clear by relatin
44 ion of anxiety and its neural circuitry, the ethical and technical limitations in exploring neural un
45 at such early stages of development and the ethical and technical restrictions that limit the feasib
46 he authors provide their views on the legal, ethical, and clinical ramifications of such restriction.
47 ing several factors, such as organisational, ethical, and economic factors, we suggest that there are
50 nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to pe
54 and were eligible for pooling given adequate ethical approval and availability of essential variables
63 le (and when they are desirable) in terms of ethical arguments and regulatory requirements, how a pla
64 re compelling epidemiological, economic, and ethical arguments for setting a global measles eradicati
65 of geolocators on small bird species but the ethical aspects and scientific benefits should always be
66 Here I discuss the scientific, technical and ethical aspects of using CRISPR (clustered regularly int
67 he study proposes a possible roadmap for the ethical assessment of sham surgery clinical trials (CTs)
68 ality of results, providing that an accurate ethical assessment procedure is in place, firstly to ens
71 an ethical framework to identify and assess ethical challenges and plan for solutions is a priority.
73 dations and guidelines for the management of ethical challenges encountered by donation physicians.
76 inary working group was assembled to address ethical challenges in US-based HIV phylogenetic research
79 amples from PATC3H research highlighted many ethical challenges that affect adolescent participation,
80 ticipation of actual, potential or perceived ethical challenges with the role, Canadian Blood Service
81 Modern medical care has also resulted in new ethical challenges, for example, those related to deacti
82 eatening condition but, due to practical and ethical challenges, there is a paucity of robust evidenc
91 ittee of Qom University of Medical Sciences (ethical code: IR.MUQ.REC.1397.075); the study was also r
93 ephrology have identified ten broad areas of ethical concern as priority challenges that require coll
95 h and biomedical therapies, new and existing ethical concerns abound throughout the global community
98 cells (iPSCs) provided a means for avoiding ethical concerns associated with the use of cells isolat
99 transplantation in rodents have accentuated ethical concerns associated with these entities, especia
100 ion, this article addresses several critical ethical concerns implicated by the often vulnerable popu
101 incentive-and identify heightened and novel ethical concerns in the context of a global pandemic.
102 n implementation particularly revolve around ethical concerns regarding lack of trust in the diagnost
104 -infected mosquitoes, in part because of the ethical concerns related to exposing a human subject's a
105 as come under scrutiny, with critics raising ethical concerns related to the adequacy of participant
111 mitigate this disparity, we discuss relevant ethical considerations and offer practical recommendatio
112 pproach to codes that respects the important ethical considerations in caring for the critically ill
113 tive care, clinical trial participation, and ethical considerations regarding the use of lifesaving m
114 gh chimeric research, as well as fundamental ethical considerations such as those concerning the prov
115 indications and contraindications, addresses ethical considerations, and highlights the need for furt
116 terion, review current clinical evidence and ethical considerations, and make recommendations for tra
117 ransferring patients supported by ECMO); and ethical considerations, areas of uncertainty, and future
118 ions, interpretability, computing power, and ethical considerations, as well as their impact on denti
119 D and answers common questions regarding the ethical considerations, clinical assessment, and how UKD
126 t with communities; (2) address cultural and ethical considerations; (3) engage communities and suppo
127 control group, which was not included due to ethical considerations; clinical study requirements impo
129 ion and distribution incur environmental and ethical costs, young people make lasting behavioural cha
130 ic data, as well as opportunities to promote ethical data sharing that accelerates science by alignin
133 fferences were found in all seven factors of ethical decision-making climate measurement, the factors
136 Physicians had more positive perceptions of ethical decision-making climate than nurses in all 13 pa
137 cal decision-making climates, ICUs with poor ethical decision-making climates had the greatest discor
140 sis, ICUs were categorized according to four ethical decision-making climates: good, average with nur
142 most aspects of society, and scientists face ethical decisions as a routine part of their work, but s
145 lacement therapy poses several practical and ethical dilemmas of global relevance for patients, clini
147 n HIV cure-related studies and addresses the ethical dilemmas raised by these studies, with recommend
148 ed by partial regulatory frameworks, intense ethical discussions, and meaningful changes in social be
149 rked great interest in other uses of CBD, in ethical drugs and botanical supplements as well as in fo
154 ve processes of bounded ethicality-including ethical fading, motivated blindness, and the slippery sl
156 ican Society of Clinical Oncology's (ASCO's) ethical framework for incorporation of research biopsies
157 In this article, the authors propose an ethical framework for using and sharing clinical data fo
160 on context and emphasize that regulatory and ethical frameworks are required to guide their use.
162 c changes in the epidemiology, economics and ethical frameworks for the treatment of kidney failure.
166 d its policy recommendations to promote five ethical goals: 1) to protect highly vulnerable patients,
167 er, such "A/B tests" are often criticized on ethical grounds even as similar, untested interventions
171 in the 1960s, unknown toxicity, cost and the ethical hurdles of research in humans have hindered the
173 spective to inform key considerations in the ethical implementation of immunity passport policies.
175 this practice need to be quantified and the ethical implications must be addressed before it can be
176 g in kidney disease prevention and care, the ethical implications of genetic kidney diseases, respons
181 ion with zebrafish constitutes a complicated ethical issue that calls for the exploration of alternat
182 Six such fallacies are presented: it is an ethical issue, only applies to "bad apples", experts are
184 possible after a thorough assessment of the ethical issues and the impact of allocation policies.
185 ing human organoids and gastruloids involves ethical issues associated with their derivation as well
187 d donors for chain-initiating kidneys raises ethical issues concerning the consent process for each i
188 media communities magnify and modify extant ethical issues in deceased and living donation related t
190 Society of Nephrology Joint Working Group on Ethical Issues in Nephrology have identified ten broad a
191 linicians must carefully consider these core ethical issues in order to make the most of this excitin
194 c testing carries great promise, but several ethical issues must be considered whenever such testing
195 ses of autoimmune psychoses, and discuss the ethical issues posed by this challenging diagnostic cate
196 on on pregnant women and their fetuses raise ethical issues regarding consent for future data mining
197 ticle first analyzes important technical and ethical issues regarding new smartphone apps that facili
198 Policy, we provide an overview of the major ethical issues related to dialysis provision worldwide,
200 objective of this article is to explore core ethical issues related to physician-assisted suicide and
202 in the Framework and fourth, we examine the ethical issues that arise at each stage of IDEAL and und
203 and mechanisms of kidney diseases but raises ethical issues that risk the successful implementation o
204 nt to the uDCD process, and to deal with the ethical issues that this practice poses: termination of
205 cally been used to elicit anxiety, but poses ethical issues when testing vulnerable populations.
206 domised controlled trials (partly because of ethical issues), few prospective and long-term studies,
213 ent research into nonopioid pain management, ethical lapses in corporate marketing, historical stigma
218 interpretation of genetic test results; and ethical, legal, cost, and privacy issues related to gene
219 Barriers to uDCD are of a logistical and ethical-legal nature, as well as arising from the lack o
220 cause clear communication of prognosis is an ethical mandate, more research is needed to provide an e
223 ptible to approaches that could undercut the ethical mission of IRBs to protect and promote the right
224 ined with growing economic pressures and the ethical need to minimise the use of laboratory animals,
226 ts a doable Grand Challenge for humanity, an ethical obligation and a smart economic objective to ach
228 actor A (VEGF-A) or buffered saline placebo (ethical obligations precluded use of a non-translatable
229 om people and populations comes with serious ethical obligations related to privacy and confidentiali
230 for clinical practice, breaches researchers' ethical obligations to participants, and represents an i
232 cause such activities do not require further ethical oversight, informed consent, or protections for
233 uely intense physician-patient relationship, ethical patient selection, ensuring patients have adequa
241 ntelligence has led researchers to study the ethical principles that should guide machine behavior.
242 s, to come, it is critical to reconsider the ethical principles underlying modern medicine and ophtha
243 atment-resistant depression does not violate ethical principles; however, clinicians and professional
245 areas for future research, and discusses the ethical problems faced by investigators at each IDEAL st
248 s and (2) how to establish a transparent and ethical process for subject recruitment while maintainin
250 tions in transplant hosts is a more relevant ethical question in the near term than the possibility o
251 differing positions on the first three core ethical questions and achieved unanimity on how critical
252 dvances in human genome editing and consider ethical questions and potential clinical implications of
255 S inevitably evokes religious, cultural, and ethical questions influencing the feasibility and sustai
257 waste time and resources but also may raise ethical questions, especially in drug development studie
259 n humans is almost impossible due to obvious ethical reasons and the sporadic nature of outbreaks.
260 limitation is the referral of AM cases (for ethical reasons) by study enumerators as part of the mon
261 ferral of AM cases by our research team (for ethical reasons) during monthly measurements in the long
263 research in global health does not describe ethical, regulatory, or practical considerations require
267 rated vector control programs, as well as an ethical responsibility to care for these individuals and
268 Intensive care teams are not meeting their ethical responsibility to recognize impending death and
269 inancial and logistic challenges, subject to ethical restrictions in children, and limited in older i
272 approval for the study was obtained from the ethical review board of the Netherlands Association for
273 of adolescents' lives, and variation in how ethical review committees assess adolescent studies.
275 ms, and potentially reduced standards in the ethical review of research by institutional review board
276 is designed to cultivate a campus culture of ethical science and engineering research in the very wor
278 ognizing that its research may raise various ethical, social, and philosophical issues, the HBP has m
279 century science demands compliance with the ethical standard of data sharing of metagenomes and DNA
281 ecognized the ways such research circumvents ethical standards by putting people, including those out
282 ased cost-effectiveness without compromising ethical standards or the overall statistical integrity o
283 such research is done following the highest ethical standards that both protect human subjects and i
286 ed four issues highlighting the key areas of ethical tension central to evaluating physician-assisted
288 over the world, we do not believe that it is ethical to contemplate withholding clinically proven ben
290 study aims to provide a paradigm when it is ethical to perform cardiopulmonary resuscitation (CPR) o
291 e that the victims are blameworthy and it is ethical to take actions or policies that might harm them
292 ttle in the way of guidance (either legal or ethical) to assist centers that accommodate it in distin
294 s could simplify decision-making and promote ethical use by enabling local communities to decide whet
295 This statement highlights our consensus that ethical use of AI in radiology should promote well-being
299 ad donor strategy is more acceptable from an ethical viewpoint, but its feasibility is currently unpr
300 Recruitment bias was avoided through an ethical waiver to patient consent; a mixture of rural, u