ライフサイエンスコーパス: ethyl group

1 ity observed with the naturally occurring C5 ethyl group.

2 inyl substituents at the 2-position of the 5-ethyl group.

3 tion and reactivation or aging on loss of an ethyl group.

4 corresponding to the presence of a methyl or ethyl group.

5 being able to differentiate a methyl from an ethyl group.

6 dem oxidation and amidation of an unreactive ethyl group.

7 the heme vinyl substituents are replaced by ethyl groups.

8 inor when propyl groups were substituted for ethyl groups.

9 hosphonate)s containing a 2-phenyl (37) or 2-ethyl group (38), were prepared as metabolically stable

10 tability, but those of the 2-(N-benzoylamino)ethyl group (A-C) were the most stable.

11 lacement of the 4-hydroxy group of 1 with an ethyl group abolishes activity (42), but again, incorpor

12 ethyl group of R-naproxen was replaced by an ethyl group) acts as a potent AKR1C3 inhibitor that disp

13 ement of the substrate's methoxy groups with ethyl groups affords a statistical 3:1 (anti,syn:syn,syn

14 yl adenosine revealed a binding site for the ethyl group against Trp-123, a residue that reaches acro

15 Provided that the ethyl group always prefers the cyclopropyl position as i

16 i system due to the steric impact of the two ethyl groups, an observation that explains the lack of e

17 phosphate oxygens is covalently linked to an ethyl group and cannot be protonated.

18 red in 2.7% of the patients in the icosapent ethyl group and in 2.1% in the placebo group (P=0.06).

19 re increased steric interactions between the ethyl group and the carbonyl-LiN(TMS)(2) moiety destabil

20 eavage of the C-O bond of the N-[2-(vinyloxy)ethyl] group and removal of vinyloxide-anion leading to

21 es, a C-8 vinyl substituent is reduced to an ethyl group, and in the case of BChl c(F), the C-8(2) ca

22 ctions of ketones with an adjacent methyl or ethyl group are generally unselective, but that bulkier

23 Ethyl groups are transferred slowly, and propyl and buty

24 butyl substituents and additional methyl and ethyl groups (as in sterically hindered phenalenyl radic

25 ed in 17.2% of the patients in the icosapent ethyl group, as compared with 22.0% of the patients in t

26 were observed for compounds that contain an ethyl group at C-9, with larger C-9 substituents tending

27 y synthesized compounds, compound 15 with an ethyl group at the 4-position showed the best activity a

28 Replacing the ethyl group at the 6-position with butyl or methyl group

29 dicated a possible binding mode in which the ethyl group at the 9-position of the molecule was orient

30 orm pyridinium salts with beta-(alkylammonio)ethyl group at the nitrogen atom in the presence of 2 eq

31 ed DNA is constrained by the geometry of the ethyl group bridging the cytosine amines.

32 eme 2-vinyl into a 1-hydroxy-2-(methylperoxy)ethyl group [-CH(OH)CH2OOCH3].

33 Namely, the disorders of flexible ethyl groups coupled with nonequivalent intra- and inter

34 This computational study reveals that ethyl group dehydrogenation begins with activation of a

35 The configuration of the N-1-(1'-naphthyl)ethyl group dictates the conformation of the O-tert-buty

36 the photo-cleavable di-methoxy nitro phenyl ethyl group (DMNPE) group.

37 erivatives of the 2-[N-methyl-N-benzoylamino]ethyl group (E-G) demonstrated moderate stability, but t

38 erature (1)H NMR spectroscopy indicates fast ethyl group exchange between Ar(C2H5)SnSn(C2H5)Ar (Ar =

39 on of the indole N-1 position with methyl or ethyl groups gave a 10- to 30-fold decrease in affinity

40 ctural analog of DES that lacks hydroxyl and ethyl groups, had no effect on CRAC current and on store

41 -1H-imidazole-5-carboxylate), in which the 2-ethyl group has been replaced by photoactivable groups b

42 Loss of ethyl groups in reactions with triethylamine also occur

43 ther amine substituent, a 2-(cyclohexen-1-yl)ethyl group, induces a hydrophobic pocket in which it bi

44 case of BChl c(F), the C-8(2) carbon of this ethyl group is subsequently methylated once or twice by

45 The fourth substituent in 1, the ethyl group, is exo-bonded to one of the six available G

46 ated in forming a complete set of deuterated ethyl groups, merging with the Diels-Alder reaction, a n

47 an antifungal polyketide that bristles with ethyl groups mounted onto a caged heterotricyclic core.

48 In outside-out patches, QA ions in which ethyl groups of TEA were replaced by methyl groups had a

49 rmediates coordinate weakly at best with the ethyl groups of triethylsilane.

50 he preferred valence tautomer is 3a with the ethyl group on the cyclopropane ring.

51 Modeling studies suggest that the ethyl group on the N2-ethyl-dG adduct located at the 5'

52 clopropanated monoadduct exhibited symmetric ethyl groups on the malonate, consistent with regioselec

53 By deliberately incorporating inward-facing ethyl groups on the truxene faces, the resulting partial

54 Replacing the 1'-N-methyl with an ethyl group or adding a second 1'-N-methyl group signifi

55 osition showed preferential migration of the ethyl group over the methyl group to give 8-ketochlorins

56 gues of copro'gen-III were prepared where an ethyl group replaced one of the usual propionate residue

57 The chiral oxazolinyl ligand induces ethyl group selectivity through stabilizing weak interac

58 rger percentage of patients in the icosapent ethyl group than in the placebo group were hospitalized

59 a, were significantly lower in the icosapent ethyl group than in the placebo group, including the rat

60 n unusual strategy to install two additional ethyl groups that makes use of a thiocarbonyl ylide gene

61 In the icosapent ethyl group, there were minimal changes in these biomark

62 studies revealed a small structural change (ethyl group to hydrogen) caused a functional shift from

63 inal products can be accounted for by facile ethyl group transfer from phosphorus to iridium followed

64 ly substituted stereocenters with methyl and ethyl groups underscores the enzyme's remarkable selecti

65 tride [(TIMMN(Mes))Fe(IV)(N)](+) (7) with an ethyl group using the triethyloxonium salt Et(3)OPF(6).

66 ces of the bis-(2-MeImH) complex to the four ethyl groups was possible through the use of 2D (1)H NMR