ライフサイエンスコーパス: evasion

1 and implications for pathogenesis and immune evasion.

2 the glycan shield may function beyond immune evasion.

3 ronan, plays an integral role in this immune evasion.

4 uman cell membrane proteins, enabling immune evasion.

5 ercomes hypomethylating agent-induced immune evasion.

6 rs to enhance replication and promote immune evasion.

7 , leading to phenotypic variation and immune evasion.

8 PI-anchored proteins are required for immune evasion.

9 -like domain which may play a role in immune evasion.

10 (TME) that promotes tumor growth and immune evasion.

11 nment in the promotion of cancer cell immune evasion.

12 ansfer efficiency, and neutralizing antibody evasion.

13 n PD-1 and its ligands supports tumor immune evasion.

14 iseases and targeted by pathogens for immune evasion.

15 athways mediating PD-L1-driven cancer immune evasion.

16 ly play a role in protein folding and immune evasion.

17 ilm formation, host colonization, and immune evasion.

18 s), as tumours have multiple means of immune evasion.

19 nflammatory mediators, tumors enhance immune evasion.

20 t is often employed as a strategy for immune evasion.

21 evelopment and progression, including immune evasion.

22 and can reverse important aspects of immune evasion.

23 relevant mechanism of cell-intrinsic immune evasion.

24 ssues exploit PRC2 activity to enable immune evasion.

25 nd to control function and facilitate immune evasion.

26 an change as the virus mutates during immune evasion.

27 ical in cancer development, including immune evasion.

28 tion driving the selection pressure in viral evasion.

29 linking mRNA decay to adaptation and immune evasion.

30 establishment of tumors by promoting immune evasion.

31 pathogen with multiple mechanisms of immune evasion.

32 nd finely targeted mechanism of local immune evasion.

33 antitumor activity, and prevent tumor immune evasion.

34 s emerged as a key mechanism of tumor immune-evasion.

35 ontributes to malignancy and immune response evasion.

36 vation of STAT3 drive DFTD growth and immune evasion.

37 susceptibility genes and strategies of host evasion.

38 ntial of cancer cells promoting their immune evasion.

39 cell death protein 1 (PD-1)-mediated immune evasion.

40 ht to be an important driver in tumor immune evasion.

41 opism, transduction efficiency, and antibody evasion.

42 stability, efficient translation, and immune evasion.

43 the EBOV GP may enhance virus immune system evasion.

44 nown to play important roles in tumor immune evasion.

45 eliae-host associations driven by complement evasion.

46 h host genetic diversity and pathogen immune evasion.

47 defines cancer IFN responsiveness and immune evasion.

48 f nutritional immunity and complement system evasion.

49 nd a potential conserved mechanism of immune evasion.

50 scriptional plasticity, and promoting immune evasion.

51 hijacked by tumors and pathogens for immune evasion.

52 products that are implicated in viral immune evasion.

53 tivity, pathogenesis, and host innate immune evasion.

54 hampered the TME switch, and enabled immune evasion.

55 The structure revealed the mechanism of mAb evasion.

56 ations, suggesting a possible role in immune evasion.

57 atures of host association and immune system evasion.

58 may support B-ALL progression and treatment evasion.

59 intrinsic, innate, and adaptive viral immune evasion.

60 les, may help flavivirus survival and immune evasion.

61 ovel targets that contribute to viral immune evasion.

62 tions for virulence and, potentially, immune evasion.

63 nce of LpxO-dependent modification in immune evasion, 2-hydroxylation of lipid A limits the activatio

64 rch into IFN signalling complexity and viral evasion across species.

65 es to both antibiotic resistance and vaccine evasion among bacterial populations.

66 of bone marrow niches can facilitate immune evasion and activation of survival pathways favouring ma

67 lution of genetic mechanisms for host immune evasion and anti-malarial resistance has enabled the Pla

68 findings demonstrate convergence between nAb evasion and CNS neurovirulence in vivo by a frequent JCP

69 es this strain-to-strain variation of immune evasion and colonization is the polymorphic outer surfac

70 Understanding the causes of immune evasion and disease progression will identify potential

71 unveils a novel strategy of PRRSV for immune evasion and enhanced replication during infection.

72 y reveals a new strategy of PRRSV for immune evasion and enhanced replication during infection.IMPORT

73 articularly in antibiotic resistance, immune evasion and epithelial adhesion genes.

74 reater dependence on this pathway for immune evasion and hence, they exhibit more impressive patient

75 in cancer stem cell self-renewal and immune evasion and highlights the broad potential of targeting

76 or restricting HSV-1 infection, tumor immune evasion and likely also adaptive immunity.

77 g macrophage polarization, leading to immune evasion and microbial persistence.

78 eins (SLPs) fulfill critical roles in immune evasion and nutrient acquisition, but as more bacterial

79 ance, antibiotic susceptibility, host immune evasion and overall virulence.

80 Dicer is a major determinant of ZIKV immune evasion and pathogenesis and may underlie ZIKV-related m

81 glabrata appears to utilise unique stealth, evasion and persistence strategies in subverting the ons

82 t of tumor cells, might contribute to immune evasion and play an essential role in bone lesions frequ

83 studies have revealed roles in tumor immune evasion and poor responses to cancer immunotherapy.

84 e suppression, implicated in melanoma immune evasion and progression mediated via upregulation of PD-

85 ic insights into UVR-induced melanoma immune evasion and progression.See related article by Wang et a

86 ivity, thereby contributing to tumour immune evasion and promoting tumour growth in mouse models.

87 on were observed in genes involved in immune evasion and regulation of gene expression, highlighting

88 ein UL148 is posited to play roles in immune evasion and regulation of viral cell tropism.

89 del in mice revealed that EC958 employs both evasion and resistance against zinc toxicity, enabling i

90 es, ranging from metabolite uptake to immune evasion and subversion to conjugation.

91 identified p53 as a key regulator of immune evasion and suggest that TNF could be used to enhance se

92 and heterogeneous entity primed for therapy evasion and survival.

93 The results provide insight into immune evasion and the cross-species transmission of 229E and r

94 ical properties, such as AAV capsid antibody evasion and tropism, can be coevolved by combining ratio

95 ongside evidence of both synergistic (CRISPR evasion) and antagonistic (superinfection exclusion) int

96 ral support, metabolism, replication, immune evasion, and disease severity.

97 en shown to be critical for survival, immune evasion, and escape, while the importance of catabolism

98 r NSP1-1 in RVB host species tropism, immune evasion, and pathogenesis.

99 es for NSP1-1 in RVB species tropism, immune evasion, and pathogenesis.IMPORTANCE While species A rot

100 le, Ptpn2, Socs1 and Adar1) in mediating CTL evasion, and show that the lipid-droplet-related gene Fi

101 n helping with host retention, immune system evasion, and transmission.

102 Here we demonstrate that stemness and immune evasion are closely intertwined in AML.

103 ver, the bacterial proteins involved in this evasion are incompletely characterized.

104 CD47 has been shown to mediate immune evasion, as the CD47-SIRPalpha axis prevents phagocytosi

105 The mechanisms that enable immune evasion at metastatic sites are poorly understood.

106 s is that intricate sequences of pursuit and evasion behavior can often be constructed through simple

107 such an algorithmic approach to pursuit and evasion behaviors.

108 nctions in flavivirus replication and immune evasion but is absent from the virion.

109 i-host interaction, pathogenesis, and immune evasion, but their exact roles remain unknown.

110 ve translesion DNA polymerase to host immune evasion by antigenic variation.

111 um of anti-phage systems and highlight their evasion by bacteriophages.

112 al therapy, improved understanding of immune evasion by cancer cells and the discovery of selective i

113 escribe a means of anticipating HIV-1 immune evasion by dividing Env into N-glycan microdomains that

114 we identify a possible mechanism of PLA2G16 evasion by employing a dual glycan receptor-binding ente

115 Pfs47 serves as a "key" that mediates immune evasion by interacting with a mosquito receptor "the loc

116 hey suggest a conserved mechanism of APOBEC3 evasion by large double-stranded DNA herpesviruses.

117 We show that this time-dependent PPD evasion by late transcripts requires the host factor nuc

118 e review the current landscape of complement evasion by Lyme disease spirochetes and provide an updat

119 se host-associated signals to promote immune evasion by masking of a major pathogen-associated molecu

120 how that tumor-secreted Gal1 mediates immune evasion by preventing T cell migration into the tumor.

121 is, but they also contribute to tumor immune evasion by promoting a suppressive tumor microenvironmen

122 ls are dependent upon calcineurin for immune evasion by restricting the regulation of proinflammatory

123 ced autophagy or lysosome function in immune evasion by selective targeting of MHC-I molecules for de

124 Mechanisms of immune evasion can involve abrogation of leukemia cell recognit

125 ate that blocking leukocidin-mediated immune evasion can promote host protection against S. aureus bl

126 ulation of host gene expression, host immune evasion, cellular survival, and cellular transformation.

127 of a conserved prophage harboring the immune evasion cluster (IEC).

128 continuous, supplemental mechanism of immune evasion co-opted by tumors to evade antitumor immunity a

129 h metastatic aggressiveness including immune evasion, collective dissemination of tumor cells, and em

130 experiments, a proposed mechanism for immune evasion consists of increased avidity to host cellular r

131 This mechanisms of immune evasion could have implications for treatment of severe

132 ar signaling molecule responsible for immune evasion during leukemia progression and raises the prosp

133 However, the mechanisms of immune evasion during leukemia progression remain poorly unders

134 unity and explain how a family of cGAS-STING evasion enzymes evolved from viral proteases through gai

135 pathogenicity, molecular mimicry, and immune evasion, expanding our understanding of host-microbe int

136 a new function for this protein as an immune evasion factor.

137 ication and is the major viral innate immune evasion factor.

138 turbulent streams, we found that areal CO(2) evasion fluxes from mountain streams equal or exceed tho

139 rising both downstream transport and gaseous evasion) for the two main landscape components, that is,

140 olipid axis in driving susceptibility to and evasion from ferroptosis, highlights PUFA-ePL as a disti

141 d studies of the in vivo consequences of CMV evasion from IgG responses in nonhuman primate models.

142 ression is an evolved trait that facilitates evasion from immune recognition by MAIT cells and contri

143 tivity of antigens have been correlated with evasion from neutralizing antibody responses.

144 conformation potentially facilitates immune evasion from RBD-up binding antibody.

145 e ecosystem "disservices" via greater carbon evasion from streams and rivers.

146 ring with Sp1-dependent gene expression, and evasion from this restriction may facilitate spread of H

147 e conclude that FnBPB provides a dual immune-evasion function that captures histones and prevents the

148 y provides molecular understanding of immune evasion functions of ZIKV, which may guide vaccine and a

149 responses is attributable to the many immune evasion genes encoded within its genome.

150 r microenvironment that contribute to immune evasion has become an important area of research.

151 expression and contributing to cancer immune evasion, highlighting the potential for repurposing copp

152 alization as a potential mechanism of immune evasion.IMPORTANCE HSV-1 causes lifelong infection in th

153 eplication in the nucleus facilitates immune evasion.IMPORTANCE We used intracellular nanobodies to b

154 findings provide a new mechanism for immune evasion in cancer and highlight the pathogenic effects o

155 kinases and as receptors that mediate immune evasion in cancer progression.

156 ategies for overcoming PD-L1-mediated immune evasion in cancer.

157 findings identify a new modality for immune evasion in PDA that depends on IL1beta production by tum

158 ty has emerged as a mode of targeted therapy evasion in various cancers, ranging from prostate and lu

159 Common mechanisms of evasion include impaired antigen presentation caused by

160 Immune evasion is a major obstacle for cancer treatment.

161 Cancer immune evasion is achieved through multiple layers of immune to

162 Immune evasion is critical for viral persistence.

163 Viral immune evasion is currently understood to focus on deflecting C

164 protection against HCV infection and immune evasion is only partially understood.

165 Atmospheric evasion is the main methane sink once runoff reaches the

166 One mechanism of evasion is to mobilize actin to the bacterial surface.

167 flexibility is thought to facilitate immune evasion, it may also reflect the heterogeneity of red bl

168 prey-specific patterns of evasion success ('evasion landscapes') as the basis for predicting how dir

169 portant role in virus replication and immune evasion, making it an attractive target for antiviral th

170 observe a predator and, hence, instigate an evasion manoeuvre.

171 ted severity of HFMD, suggesting that immune evasion may be an indirect driver for virulence (154 wor

172 ses suggesting a key mechanism of cGAS-STING evasion may have evolved outside of mammalian biology.

173 Our findings reveal an immune evasion mechanism and have implications for the design o

174 During evolution, this novel viral immune evasion mechanism could have prompted the development of

175 mor microenvironment (TME) is a major immune evasion mechanism in some patients with cancer, and anti

176 tivity of HSV1 VP1-2 is a major viral immune-evasion mechanism in the brain.

177 These results unveil an immune-evasion mechanism mediated by the esophageal gland, whic

178 how that gene amplification is an additional evasion mechanism used by Plasmodium vivax to escape hum

179 , cancer methionine consumption is an immune evasion mechanism, and targeting cancer methionine signa

180 ctivation may function as a potential immune evasion mechanism.

181 hat will help dissect M. tuberculosis immune evasion mechanisms and devise strategies to bypass them

182 work expands knowledge of the innate immune evasion mechanisms associated with NEMO cleavage by arte

183 osystem provides deeper insights into immune evasion mechanisms associated with tumor relapse.

184 teraction analyses revealed potential immune evasion mechanisms in recurrent tumor cells that dampen

185 wing to lack of power or to efficient immune evasion mechanisms that are active early during tumor ev

186 or repertoires identified novel tumor immune evasion mechanisms through genetic alterations.

187 ive drivers of tumor initiation, therapeutic evasion, metastasis, and recurrence.

188 umors, and linked to tumor growth, survival, evasion, metastasis, stemness, and drug resistance.

189 Other strategies include immune evasion, microbiome-modifying therapies, and the employm

190 ural killer cells or T cell recognition, the evasion of antibody-mediated effects does not seem to be

191 s (HCV) co-opts the host protein CypA to aid evasion of antiviral responses dependent on the effector

192 vade host innate immunity, which include the evasion of antiviral type I interferon (IFN) responses.

193 Additionally, a MT2A-dependent cellular evasion of apoptosis during cisplatin could be observed,

194 ponses, thus potentially contributing to the evasion of cancer cells from immune surveillance.

195 ty to HIV-1 capsid facilitating simultaneous evasion of capsid-targeting restriction factors includin

196 g cellular growth restriction, including the evasion of cellular senescence, is a hallmark of cancer.

197 wn for their pathological role in neoplastic evasion of chemotherapeutics and antibiotics.

198 of host complement to facilitate spirochete evasion of complement killing.

199 To facilitate the evasion of complement, Lyme borreliae produce diverse pr

200 phagy pathway as a conserved mediator of the evasion of CTLs by cancer cells, and show that this path

201 ays act in cancer cells to orchestrate their evasion of CTLs, and shows that discrete functional modu

202 azilian strain of ZIKV and rather suggest an evasion of detection by host cell pattern recognition re

203 lfate proteoglycans (HSPGs), suggesting that evasion of DIDS lowered dependence on an initial interac

204 Since Igf1r deletion allows the evasion of early developmental arrest, interspecies fetu

205 le Chlamydia to reach the colon by promoting evasion of gastric barriers.

206 of cellular processes such as proliferation, evasion of growth suppressors, activating metastasis, an

207 philins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechan

208 by affecting the cell wall integrity and the evasion of host immune recognition.

209 alters virulence phenotypes and facilitates evasion of host immune responses.

210 y murine coronavirus plays a pivotal role in evasion of host innate immune defenses in macrophages.

211 bonuclease designated EndoU that facilitates evasion of host pattern recognition receptor MDA5, but t

212 V-1 surface protein Env, contributing to the evasion of humoral immunity.

213 e evolutionarily advantageous through better evasion of humoral responses directed against HCMV virio

214 Evasion of IFN-mediated antiviral signaling is a common

215 ic instability and inflammation, and trigger evasion of immune responses.

216 of PLC linked to chromosomal instability and evasion of immune surveillance.

217 ing, reverse transcription, integration, and evasion of innate immunity.

218 mulate HLA presentation, which may aid viral evasion of innate immunity.IMPORTANCE Human leukocyte an

219 s of autophagy control cancer-cell-intrinsic evasion of killing by CTLs and we highlight the importan

220 In contrast to viral evasion of natural killer cells or T cell recognition, t

221 ntra-individual evolution rate that promotes evasion of neutralization and persistent infection.

222 n microenvironment, which may promote immune evasion of oncogenic cells and drive melanoma initiation

223 similar phenomena could contribute to immune evasion of other viruses.

224 ribed a Trojan horse approach to therapeutic evasion of P-gp based on a reversibly linked combination

225 include features of host-searching behavior, evasion of plant defenses, plant tolerance to utilizatio

226 Selective immune evasion of PR-positive tumors may be one explanation as

227 Evasion of programmed cell death represents a critical f

228 esponse in asymptomatic subjects, the immune evasion of severe acute respiratory syndrome coronavirus

229 sized that viral factors that facilitate the evasion of such responses-namely, Nef genetic and functi

230 ctive immunity and virus survival depends on evasion of such responses.

231 We further demonstrate that, unlike evasion of T cell immunity, this viral Fcgamma receptor

232 en processing pathway (MHC-I APP), promoting evasion of T cell-mediated immunity.

233 alteration that occurred during glioblastoma evasion of targeted therapy, and offer a valuable model

234 o Midgut Screen 43) is required for parasite evasion of the Anopheles coluzzii complement-like respon

235 onal preferences of HIV-1 Env ligands; (iii) evasion of the host antibody response; and (iv) potentia

236 Evasion of the host immune responses is critical for bot

237 The ability of HPV to persist depends on evasion of the host immune system.

238 mpromise host immune cell function, allowing evasion of the host immune system.

239 Viral evasion of the immune response can lead to refractory al

240 he genetic circuits that are involved in the evasion of the immune system by cancer cells, and highli

241 dentity of a target molecule, underlying the evasion of the macrophage-mediated innate immune respons

242 ifferentially weighted toward exploration or evasion of threats.

243 ied linear mRNA in vitro, in part due to the evasion of TLR sensing.

244 in absence of NRF2 and coincided with immune evasion parameters in human melanoma datasets.

245 lying mechanism that leads to a tumor immune evasion phenotype in both humans and mice.

246 oncogenic lncRNA that mediates cancer immune evasion, pointing to a new target for immune potentiatio

247 umoral heterogeneity, metastasis, and immune evasion, presenting transformative opportunities for tar

248 e EAP family of Staphylococcus aureus immune evasion proteins potently inhibit the neutrophil serine

249 ncoding for reprogramming factors and immune evasion proteins.

250 uency-dependent selection process for immune evasion, raising issues for vaccine development.

251 T-cell turnover declines and evasion rates together explained differences in early in

252 PIK3CA, SWI/SNF-complex genes and in immune evasion regulators.

253 it is essential that M. tuberculosis immune evasion-related pathogen virulence strategies are consid

254 anisms underlying chronic illness and immune evasion remain elusive.

255 s, yet the complex mechanisms driving immune evasion remain poorly understood.

256 n and a novel mechanism for DNA virus immune evasion, resulting in increased CD8(+) T-cell memory and

257 Immune evasion strategies adopted by Leishmania donovani involv

258 derstanding of viral pathogenesis and immune evasion strategies but also of the immune signaling casc

259 We discuss immune evasion strategies during early infection, from disrupti

260 ar mechanisms of the antiviral host response evasion strategies of FMDV may help to develop counterme

261 which exploit host signals to trigger immune evasion strategies that protect them against imminent im

262 lar environment, and its multifaceted immune evasion strategies.

263 as a critical component of the cancer immune evasion strategy and can be an effective immunotherapy t

264 Additional study of this evasion strategy and how to mitigate it could enhance ou

265 data reveal that IL-36 overcomes this immune evasion strategy by increasing cellular sensitivity to I

266 Isolates exhibiting this evasion strategy carry candidate mutations, generating s

267 A unique gonococcal immune evasion strategy involves capping of lipooligosaccharide

268 HIV-1 does not employ this potential immune evasion strategy is not fully understood.

269 nd to be downregulated, suggesting an immune evasion strategy of A. invadans in establishing the infe

270 ese results identify an unanticipated immune evasion strategy of Mtb in the BM that controls the magn

271 tion and spectrum of activity of this immune evasion strategy remain largely unknown.

272 resents a sophisticated but efficient immune evasion strategy to allow transfer of progeny virus from

273 that PD-L1 expression is an important immune evasion strategy used by KSHV for its survival and maint

274 eisseria gonorrhoeae deploys a unique immune evasion strategy wherein the lacto-N-neotetraose termini

275 n a highly effective and paradigmatic immune evasion strategy.

276 abitat domains and prey-specific patterns of evasion success ('evasion landscapes') as the basis for

277 These immune evasion tactics blunt the effectiveness of immunization

278 e known antiviral immune responses and virus evasion tactics in the context of DNA virus infection.

279 scribe a novel mechanism of CLL tumor immune evasion that is independent of T-cell exhaustion, using

280 f LANA to modulate its expression and immune evasion through formation of G-quadruplexes in its mRNA.

281 or tumour-expressed CD24 in promoting immune evasion through its interaction with the inhibitory rece

282 yme activation-induced deaminase, and immune evasion through major histocompatibility complex class I

283 Immune evasion through membrane remodeling is a hallmark of Yer

284 tumor-promoting functions and promote immune evasion through multiple mechanisms, but as yet, no CAF-

285 gnaling adaptors MYD88 and CD79B, and immune evasion through mutation of antigen-presenting genes.

286 cer, tumor cells employ mechanisms of immune evasion to avoid elimination by protective CD4(+) and CD

287 Our data attribute this 2-5AMD evasion to better stability of defense mRNAs and positiv

288 s can be exploited to overcome cancer immune evasion triggered by conventional or targeted therapies.

289 ssor cells (MDSCs) are key players in immune evasion, tumor progression and metastasis.

290 ere, we review studies of animal pursuit and evasion - two special classes of behavior where theory-d

291 ding, as it highlights a mechanism of immune evasion utilized by HCMV to decrease the expression of M

292 5b-9 showed that the underlying mechanism of evasion varied in the four strains: B5055 and NTUH-K2044

293 e describe a novel mechanism of HSV-1 immune evasion via ICP22-dependent downregulation of the host T

294 de new insights into the mechanism of immune evasion via m(6)A modification of viral RNAs.

295 s well as investigate glycan-mediated immune evasion via molecular mimicry.

296 olved in host colonization and immune system evasion were detected across the MAGs.

297 bind PIMMS43 interfere with parasite immune evasion when ingested with the infectious blood meal and

298 cers that produces multiple routes to immune evasion, which are clinically relevant and forecast poor

299 tated colonisation, dissemination and immune evasion within the novel finch host.

300 y Pg and its prolonged survival by autophagy evasion within these cells suggest a strong rationale fo