ライフサイエンスコーパス: eviction

1 ional to the timescale for active nucleosome eviction.

2 hole whose binding results in stable histone eviction.

3 d has been implicated in promoter nucleosome eviction.

4 tone acetylation is important for nucleosome eviction.

5 ning nucleosomes without ensuing histone H2A eviction.

6 es and suppressing cotranscriptional histone eviction.

7 ex promotes transcription through nucleosome eviction.

8 the CTCF binding site, and, eventually, CTCF eviction.

9 e the ATR kinase, showed no overt nucleosome eviction.

10 ake place in the absence of overt nucleosome eviction.

11 , histone variant incorporation, and histone eviction.

12 ubunit is essential for ORC-mediated histone eviction.

13 rtially unwrapped nucleosome without histone eviction.

14 anslation as a consequence of defective eIF6 eviction.

15 d targets to invest more effort in resisting eviction.

16 BAF complexes have different effects on PRC eviction.

17 ls, finding impaired histone acetylation and eviction.

18 a 1.74-fold increase in children's hazard of eviction (95% confidence interval: 1.02, 2.95), and leng

19 including 10 135 births to women who had an eviction action during pregnancy and 78 727 births to mo

20 727 births to mothers who had experienced an eviction action when not pregnant.

21 Compared with mothers who experienced eviction actions at other times, eviction during pregnan

22 Eviction actions occurring during gestation.

23 Our findings underscore that histone eviction alone, rather than DNA breaks, contributes stro

24 oned nucleosomes where it induces nucleosome eviction, alters local histone modifications, and remode

25 er households every year are threatened with eviction, an event associated with severe negative impac

26 5 studies, 4 reported an association between eviction and adverse child health outcomes.

27 examining an association between exposure to eviction and at least 1 health outcome, both before age

28 year observations (across 40 states) used US eviction and census data for the years 2002 through 2018

29 NMT3A(R882) cells showed impaired nucleosome eviction and chromatin remodeling in response to anthrac

30 Mortality based on linked eviction and death records from 2020 through 2021 was co

31 Asf1 mediates histone H3, but not H2B, eviction and deposition during Pol II elongation, sugges

32 Since ASF1 mediates eviction and deposition of histones during transcription

33 cations for ATP-driven mechanisms of histone eviction and deposition.

34 tion, histone variant expression, nucleosome eviction and DNA damage repair.

35 ncreased 5-methylcytosine, resulting in CTCF eviction and exon exclusion.

36 adverse birth outcomes, our results suggest eviction and health may be cyclical and co-constitutive.

37 leosome stability and facilitates nucleosome eviction and hence gene expression in vivo.

38 ates a highly dynamic equilibrium of histone eviction and histone deposition and that there is signif

39 Eviction and housing loss are pressing public health con

40 Results show eviction and inability to pay rent/mortgage were both as

41 on of the leading edge by driving sequential eviction and intercalation of individual cells away from

42 we identify chaperones that can mediate the eviction and loading of Mst77F on DNA, thus facilitating

43 ficant undercount of individuals impacted by eviction and motivates policies designed to stabilize ho

44 va face a similarly challenging task of SNBP eviction and reassembly of nucleosome-based chromatin.

45 ing adverse birth outcomes are vulnerable to eviction and require additional supports.

46 ied by Swi-Snf recruitment, promoter histone eviction and Sas3 and Ada2(Gcn5)-dependent histone H3K14

47 ed a striking correlation between nucleosome eviction and strong activator and acetyl-CoA-dependent t

48 tion of Gcn4 and Tup1 enhances Gcn4 promoter eviction and that multiple Tup1-interacting proteins bec

49 tivation, facilitating its eventual promoter eviction and transcriptional shut off.

50 bilizes the nucleosome by preventing H2A-H2B eviction and, thereby, retains the "docking site" for Se

51 out meta-analysis of the association between evictions and child health outcomes, evidence demonstrat

52 listically heterogenous cities in which both evictions and contacts occur more frequently in poorer n

53 rs are unjustly burdened by both residential evictions and psychological distress.

54 se depletion: enhanced Atf1 binding, histone eviction, and histone H3 acetylation.

55 their capacity to induce DNA breaks, histone eviction, and relocated topoisomerase IIalpha in living

56 nt nucleosome repopulation that occurs after eviction, and the strongest effects of Ash1 are seen whe

57 eeding competition, dominance behaviour, and evictions, and 3) relative to subordinates, produce offs

58 bility crisis, ongoing racial disparities in evictions, and continuing harm to millions of families,

59 More than 2 million families face eviction annually, a number likely to increase due to th

60 ing in a renter household is threatened with eviction annually, while one in ten is evicted.

61 nd its chromatin recruitment, spreading, and eviction are exquisitely regulated via interactions with

62 ion moratoria and show that policies to stem evictions are a warranted and important component of COV

63 adox points to nucleosome destabilization or eviction as a defining feature of the meiotic resection

64 Collectively, our work reports on histone eviction as an immediate cellular response to PARPi trea

65 In models including both housing exposures, eviction associations were attenuated, while estimates f

66 en involves chromatin remodeling and histone eviction at active promoters.

67 one child in their home were threatened with eviction at an annual rate of 10.4%, twice that of adult

68 hough transcriptional activation and histone eviction at CHA1 depends on Swi/Snf, Swi/Snf recruitment

69 stone chaperone each required for nucleosome eviction at distinct promoter regions.

70 r treatment suppressed the immediate histone eviction at DNA lesions.

71 nd by CTCF during latency and underwent CTCF eviction at early times postreactivation in mice latentl

72 uggest that Swi/Snf is important for histone eviction at enhancers and that it also functions as a Po

73 the preinitiation complex (PIC), in histone eviction at inducible and constitutively active promoter

74 utants implicated Gcn5, Snf2, and Ydj1 in H3 eviction at most, but not all, Gcn4 target promoters, wi

75 we observed a distinct mechanism of histone eviction at the Alad1b promoter.

76 remodeling complex to restore normal histone eviction at the damage sites.

77 t not SPT3 or SPT8 impaired promoter histone eviction at the highly remodeled subset of induced genes

78 nf recruitment is not sufficient for histone eviction at the induced CHA1 promoter.

79 se three cofactors cooperate similarly in H3 eviction at virtually all yeast promoters.

80 negative kin discrimination is restricted to eviction attempts of older females capable of resistance

81 ivation after glucose shutoff caused histone eviction both at 601 and elsewhere in the ORF.

82 a novel activity, which prevents nucleosome eviction but not remodeling mediated by the ATP-dependen

83 involve chromatin remodeling and nucleosome eviction, but whether dysfunctional telomeres undergo ch

84 ding Protein (TBP) was the most resistant to eviction by PRC1.

85 ome sliding by SNF2h while promoting octamer eviction by the SWI-SNF complex, RSC.

86 ssed only in mother cells where a nucleosome eviction cascade along the promoter during the cell cycl

87 lly, inactivation of RNAPII itself abolishes eviction completely.

88 ur discovery points to a direct link between eviction-coupled erasure of the ubiquitin mark from ubH2

89 Here, we link 38 million eviction court cases to US Census Bureau data to show th

90 ing the COVID-19 pandemic could result in an eviction crisis in US cities.

91 nce behaviour, is associated with infrequent evictions, decreases social centrality within the clan,

92 ent with a role for Vps75 in histone H2A/H2B eviction/deposition during transcription.

93 cify distinct downstream patterns of histone eviction/deposition.

94 or limited nest sites was a primary cause of eviction-driven infanticide, and 2) attacks occurred les

95 pitation studies demonstrate that histone H3 eviction during active transcription is decelerated in a

96 experienced eviction actions at other times, eviction during pregnancy was associated with lower infa

97 Given documented associations between evictions during pregnancy and adverse birth outcomes, t

98 Our studies reveal that H3 incorporation and eviction dynamics identify cells with different cell div

99 ng 2.9 million children, faced the threat of eviction each year between 2007 and 2016.

100 households, on average, are threatened with eviction each year; that the highest eviction filing rat

101 reflect cause, government efforts to prevent evictions (eg, right to counsel in housing court) or low

102 r, reported violent crime, impervious areas, evictions, election participation, income, poverty, educ

103 pletion of Ino80 impairs promoter nucleosome eviction even in a mutant lacking H2A.Z.

104 D during pregnancy that were associated with eviction filing and judgment rate trajectories incorpora

105 In adjusted models, higher neighborhood eviction filing and judgment rates, as compared with low

106 ed with eviction each year; that the highest eviction filing rates are not concentrated solely in hig

107 es are strongly associated with county-level eviction filing risk.

108 Renters who received eviction filings experienced substantial excess mortalit

109 Eviction filings were 44.7% lower than expected during t

110 ms the strong dependency on NAP1-mediated H1 eviction for induction of the silent CD40 gene and furth

111 nds to chromatin to promote broad nucleosome eviction for transcriptional activation of many cancer p

112 sfer activity, resulting in targeted histone eviction from a nucleosome probe.

113 , inactivation of Gcn5p decreases nucleosome eviction from both GAL1 and a long ( approximately 8 kb)

114 tiple phosphorylation events promote FOXP2's eviction from chromatin and supplant the solubilizing fu

115 it forms en route to deposition or following eviction from chromatin remains limited.

116 oading to chromatin, catalytic activity, and eviction from chromatin.

117 g proteins after their ubiquitination at and eviction from chromatin; as a deubiquitinase, specific t

118 eir deposition onto DNA, and aiding in their eviction from DNA.

119 thus reveals an unsuspected role of histone eviction from insect sperm chromatin: safeguarding the i

120 Nucleosome eviction from Msn2p binding sites was common across the

121 ular disulfide bonds in protamines and their eviction from sperm during fertilization.

122 duals are specifically targeted for forcible eviction from the group, often suffering severe injury,

123 Histone eviction from the PHO5 promoter during activation occurs

124 ion by RNAPII affect the kinetics of histone eviction from the PHO5 promoter.

125 Concomitantly, Nog1 eviction from the pre-60S permits peptidyl transferase c

126 in-associated mechanism required for RNAPIII eviction from tRNA genes and tuning the physiological re

127 alating aggression, culminating in temporary evictions from the group.

128 Although evictions have been associated with adverse mental healt

129 the Swi/Snf complex is required for histone eviction in a manner that is independent of transcriptio

130 ation and enhanced RSC occupancy and histone eviction in coding sequences and stimulates the rate of

131 etylation-mediated nucleosome remodeling and eviction in coding sequences that stimulates transcripti

132 Defective H3 eviction in cofactor mutants was coupled with reduced Po

133 Defects in nucleosome eviction in ino80Delta cells are frequently accompanied

134 ession of plasmid replication and/or plasmid eviction in multiple orthogonal readouts and potentiated

135 RSC, and H2AZ are dispensable for robust H3 eviction in otherwise wild-type cells.

136 motes chromatin accessibility and nucleosome eviction in spermiogenesis and that loss of histone acet

137 ntiation, revealing a common principle of H3 eviction in the proliferating and endocycling domains of

138 ve linked the activity of SWI/SNF to histone eviction in trans from gene promoters.

139 (Pol) II, but a factor that mediates histone eviction in vivo has not yet been identified.

140 may account for SWI/SNF-dependent nucleosome eviction in vivo.

141 H3 eviction is a fast process occurring within the G2 phase

142 and FACT is recruited to these regions when eviction is beginning.

143 These findings indicate that nucleosome eviction is crucial for robust transcription of highly e

144 le-molecule resolution, and found that H2A.Z eviction is dependent on RNA Polymerase II (Pol II) and

145 This finding suggests that histone eviction is modulated by factors that are not linked to

146 ting to an active state including nucleosome eviction is required for activation of protein expressio

147 Premature thymic eviction is triggered by T cell receptor (TCR)-driven do

148 50 to -0.48; P = .047) and reductions of the eviction judgment rate by -0.25 (95% CI, -0.35 to -0.14;

149 0.22 (1575.19) eviction judgments (mean [SD] eviction judgment rate, 1.89 per 100 households) post-20

150 7.22 (1592.18) eviction judgments (mean [SD] eviction judgment rate, 1.91 per 100 households) pre-201

151 judgments in the post-2014 period (mean [SD] eviction judgment rate, 2.02 [1.81] per 100 households).

152 ed with reductions in eviction judgments and eviction judgment rates; however, these associations wer

153 nty eviction judgments were 477.22 (1592.18) eviction judgments (mean [SD] eviction judgment rate, 1.

154 0 households) pre-2014, and 490.22 (1575.19) eviction judgments (mean [SD] eviction judgment rate, 1.

155 expansion was associated with reductions in eviction judgments and eviction judgment rates; however,

156 ion was associated with reductions in county eviction judgments by -66.49 (95% CI, -132.50 to -0.48;

157 ated, without Medicaid expansion), mean (SD) eviction judgments for treated counties were 534.78 evic

158 eholds), which decreased to 463.67 (1499.39) eviction judgments in the post-2014 period (mean [SD] ev

159 n judgments for treated counties were 534.78 eviction judgments in the pre-2014 period (mean [SD] evi

160 Eviction judgments; eviction judgments per 100 renter-occupied households.

161 Control group mean (SD) county eviction judgments were 477.22 (1592.18) eviction judgme

162 Eviction judgments; eviction judgments per 100 renter-oc

163 and August 31, 2021, were collected via the Eviction Lab's Eviction Tracking System.

164 that BAF opposes PRC by rapid, ATP-dependent eviction, leading to the formation of accessible chromat

165 cal assistance to pregnant women at risk for eviction may improve infant health.

166 Evictions may accelerate COVID-19 transmission by decrea

167 Residential evictions may have increased excess mortality associated

168 Housing insecurity induced by evictions may increase the risk of contracting COVID-19.

169 ition by H1 and establish a gene-specific H1 eviction mechanism through an activator->p300->NAP1->H1

170 s ATP dependent, consistent with a transient eviction mechanism.

171 r, p300, and acetyl-CoA-dependent nucleosome eviction mediated by the histone chaperone Nap1.

172 isaccharide) stand out, due to their histone eviction-mediated cytotoxicity toward doxorubicin-resist

173 Our results provide a basis to assess eviction moratoria and show that policies to stem evicti

174 Eviction moratoria may not be sufficient to prevent over

175 c, 43 states and Washington, DC, implemented eviction moratoria of varying durations.

176 Lifting state eviction moratoria was associated with a 0.14 per 100 00

177 and the District of Columbia implemented an eviction moratorium and 7 did not.

178 dvantage who lived in a state that issued an eviction moratorium and were diagnosed with COVID-19 as

179 ndividuals living in a state that lifted its eviction moratorium experienced higher hazards of a COVI

180 Survey to measure associations between state eviction moratorium protections and mental distress.

181 Relative to no state-level eviction moratorium protections, strong protections were

182 mortality increased steadily in states after eviction moratoriums expired, and expiration was associa

183 Moderate-certainty evidence was found that eviction moratoriums were associated with reduced COVID-

184 ion of the telomeric chromatin or nucleosome eviction near the telomere terminus.

185 Millions of rental evictions occur in the United States each year, dispropo

186 More eviction occurred on genes with 'closed' promoters, asso

187 We also show that nucleosome eviction occurs bidirectionally over a large distance.

188 Surprisingly, BAF-mediated PRC eviction occurs in the absence of RNA polymerase II (Pol

189 AR bound directly to Ifng and eviction of AR with a small molecule significantly incre

190 cal DNA replication by proteolysis-dependent eviction of CHK1 from replicative chromatin.

191 an S phase-dependent manner to assist in the eviction of crosslinked protein from DNA.

192 altered histone exchange kinetics may affect eviction of Cse4 from noncentromeric loci.

193 Preventing the eviction of EED from the Kiss1 promoter disrupted pulsat

194 In myeloid leukemia cells, it promotes rapid eviction of EP300/CBP from an enhancer subset marked by

195 In myeloma cells, CCS1477 induces eviction of EP300/CBP from FGFR3, the target of the comm

196 hat CHD1 directs short spacing, resulting in eviction of H1 and chromatin unfolding, whereas ISW1 dir

197 istone acetylation (by p300) and concomitant eviction of H1 and H2A-H2B.

198 ts PARP1/ARTD1, and initiates PARP1-mediated eviction of H1 from the chromatin fiber.

199 al changes, and arginine mutants prevent the eviction of H2A and dissociation of polyubiquitinated DD

200 dependent chromatin disruption reflects both eviction of H2A-H2B dimers and the presence of queued Po

201 eosomes at DSBs is transient, and that rapid eviction of H2A.Z is required for DSB repair.

202 dopsis HSFs, which cause a rapid and dynamic eviction of H2A.Z nucleosomes at target genes.

203 active transcription complexes is coupled to eviction of H2A.Z nucleosomes, and disassembly is couple

204 iption at yeast promoters is responsible for eviction of H2A.Z.

205 fore propose that the transcription-mediated eviction of H2A/H2B dimers is an important mechanism tha

206 The partial eviction of H3 from the nucleosomes is dependent on ubiq

207 kinetochore correlated with CENP-A seeding, eviction of H3K9me3 and local accumulation of mitotic co

208 n assembly on somatic chromatin by promoting eviction of histone H1 through its N-terminal domain.

209 say, we demonstrate that Rad26p promotes the eviction of histone H2A-H2B dimer and prevents the reass

210 e fact that Rtt109p regulates the deposition/eviction of histone H2B in addition to its role in stimu

211 Here, we show that Rtt109p promotes the eviction of histone H3 from a fast inducible yeast gene,

212 revealed that the SWI/SNF complex catalyzed eviction of histones from the Gal4-bound nucleosomes.

213 nnate immune responses, and modification and eviction of histones from viral chromatin.

214 by either sliding nucleosomes on DNA or the eviction of histones.

215 PTBP1 proceeded to assemble an EDC with the eviction of hnRNP proteins, the late recruitment of SR p

216 deler, is required for activation-associated eviction of Htz1 specifically from promoters of the Thr4

217 This down-regulation is accompanied by eviction of Ifh1p and recruitment of Crf1p, followed by

218 Eviction of Ikaros is rapidly reversed by addition of th

219 erance instead results from premature thymic eviction of immature autoreactive CD8 thymocytes into th

220 Hence, by eviction of incorrect polymerases at the fork, the clamp

221 Thus, chaperone-assisted eviction of linker histones and Shugoshins is a fundamen

222 Eviction of Mcm requires replication; during replication

223 structure at the PD-1 locus, leading to the eviction of NFATc1 from its site.

224 eads to hyperstimulation of ATPase activity, eviction of nucleosomal H2A-H2B, and deposition of H2A.Z

225 that deletion of the HBR domain impairs the eviction of nucleosomes at the promoters and open readin

226 ption in vivo are typically characterized by eviction of nucleosomes from chromatin and are experimen

227 Third, yFACT is required for eviction of nucleosomes from the GAL1-10 promoter during

228 likely in SAGA, stimulates modification and eviction of nucleosomes in transcribed coding sequences

229 urthermore, we observe transcription-coupled eviction of nucleosomes on strong TSSs during intraeryth

230 henotypes are correlated with a delay in the eviction of nucleosomes surrounding the DSB.

231 tial sensitivity of particles, including the eviction of nucleosomes.

232 graders, with treatment leading to chromatin eviction of POU2AF1 and IRF4 and decreased IRF4 signalin

233 dCENP-A in M/G1 phase, which depends on the eviction of previously deposited H3/H3.3-placeholder nuc

234 Eviction of PU.1 promotes receptor binding, increasing t

235 eine treatment results in a dosage-dependent eviction of Rad51 from ssDNA.

236 onse to hyperosmotic shock induces the rapid eviction of Rgc2 from Fps1 and consequent channel closur

237 sassembly of the preinitiation complexes and eviction of RNA Pol II from histone genes by a mechanism

238 In the absence of Fpt1, eviction of RNAPIII was reduced, and the shutdown of rib

239 deling enzyme can catalyze the ATP-dependent eviction of Sir3p from recombinant nucleosomal arrays, a

240 intron lariats, and contribute to the timely eviction of splicing factors.

241 on is not implicated in TC-NER, and moderate eviction of Spt5 and promotion of error-free transcripti

242 matid resolution during mitosis required the eviction of such H1S/T18ph by the chaperone SET, with th

243 between yeast and human Rev1, including the eviction of template G from the DNA helix and the pairin

244 rotein 1 (NAP1), cooperates with CBP/p300 in eviction of the acetylated histones from the chromatin t

245 MED1 for dephosphorylation, resulting in the eviction of the AR-MED1 complex from chromatin and loss

246 ression is induced by physiological signals, eviction of the core transcriptional machinery was accom

247 We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes a

248 recruitment promotes histone acetylation and eviction of the histone octamer from the chromatin-assem

249 Kumar and Wigge now reveal that eviction of the histone variant H2A.Z from nucleosomes p

250 Eviction of the Kex2-encoding plasmid indicated that cle

251 Significantly, eviction of the more distant nucleosomes is dependent up

252 Eviction of the stalled helicase allows leading strands

253 Eviction of the stalled helicase involves K48-linked pol

254 lide a nucleosome past a TF, with concurrent eviction of the TF from the DNA, and the TF did not sign

255 Furthermore, TSA treatment resulted in the eviction of the transcription factor nuclear factor-1 fr

256 itously, as well as the impact of nucleosome eviction on transcription genome-wide, is poorly underst

257 ing attention has been paid to the impact of evictions on child health outcomes.

258 Here we model the effect of evictions on SARS-CoV-2 epidemics, simulating viral tran

259 sults suggested a direct role for Yta7 in H3 eviction or degradation.

260 specific histones to mediate their storage, eviction or deposition from/or into chromatin.

261 Eviction or destabilization of nucleosomes from chromati

262 utilities; and 2.95 (95% CI, 1.38-6.31) for eviction or foreclosure in 2019.

263 bility to pay rent or mortgage or utilities; eviction or foreclosure; and food insecurity.

264 factors regulate nucleosome mobilization or eviction or histone exchange.

265 reproduction in subordinates via aggression, eviction or infanticide.

266 In this study, stress about eviction or loss of housing was associated with depressi

267 used to test associations with stress about eviction or loss of housing.

268 Furthermore, we show that the stimulated eviction or reduced deposition of histones by Rtt109p pr

269 Direct experience of eviction or residence in a neighborhood with more evicti

270 osition and mechanisms underlying nucleosome eviction or retention are poorly understood, including s

271 date of the population of US renters facing eviction, our study reveals a significant undercount of

272 otype, Spt6 inactivation caused localized H3 eviction over 1-2 nucleosomes at 5' ends of Ty elements.

273 acetylation, Swi-Snf recruitment and histone eviction proceed, but transcription is reduced, suggesti

274 The high H3.1/H3.3 ratio and H3.1 eviction process also occurs in endocycling cells before

275 omes, it remains unclear which stages of the eviction process are associated with mental distress amo

276 Prior to their eviction, promoter-associated histones are transiently h

277 judgments in the pre-2014 period (mean [SD] eviction rate, 2.25 [2.18] per 100 households), which de

278 Higher eviction rates have been associated with higher overdose

279 ip codes, which was associated with reducing eviction risk by half.

280 t CD40 gene and further demonstrates that H1 eviction, seeded by activator-p300-NAP1-H1 interactions,

281 fecting FACT reduce the transient nucleosome eviction seen at these promoters during a normal cell cy

282 esting that Swi/Snf is important for histone eviction that occurs during Pol II elongation.

283 the marked effect of DNA nicking on histone eviction that underscores the powerful potential of topo

284 Transcriptional activation caused histone eviction throughout the GAL1-YLR454W ORF, except at 601,

285 dition to its role in stimulating histone H3 eviction, thus providing insight into chromatin assembly

286 Job loss and evictions tied to the Coronavirus Disease 2019 (COVID-19

287 These findings link H2A.Z eviction to transcription initiation, promoter escape an

288 at dominant female meerkats employ stressful evictions to suppress reproduction among their probable

289 2021, were collected via the Eviction Lab's Eviction Tracking System.

290 Rapid RNAP2 eviction, transcriptional shutdown, nucleosome invasion,

291 es correlated with the efficiency of RNAPIII eviction upon nutrient perturbation and required the tra

292 Accordingly, compound-mediated KDM1A eviction was associated with elevated levels of local hi

293 Robust PIC-dependent H2A.Z eviction was observed at active and infrequently transcr

294 By contrast, H2A.Z eviction was unaffected upon depletion of INO80, a remod

295 ion or residence in a neighborhood with more evictions was associated with adverse perinatal outcomes

296 s such as histone H2A phosphorylation and H3 eviction were faster in absence of HMO1.

297 In this period, nearly 40% of tenants facing eviction were ordered to leave their residences because

298 , 26.26 [5.76] years) who experienced 99 517 evictions were identified during the study period, inclu

299 However, it is absent in public housing evictions, where timing rules are significantly laxer, a

300 demonstrated the deleterious associations of eviction with a range of developmental periods and domai