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1 reatment, explaining why resistance does not evolve.
2  and evolutionary history and can themselves evolve.
3 ted by a neuropeptide called kisspeptin have evolved.
4 nimal domestication are hypothesized to have evolved.
5 he question of why and how specialized sleep evolved.
6 in the form of inducible warm tolerance also evolved.
7 ng of how this core physiological system has evolved.
8 nto some of the processes by which cognition evolves.
9 d pathways through which MND is produced and evolves.
10 act of this pandemic on the airline industry evolves.
11 chronic rhinosinusitis (CRS) is continuously evolving.
12 care of solid organ transplant recipients is evolving.
13 ce AAV trafficking and transduction is still evolving.
14     Phylogenetic analysis shows that POLGARF evolved ~160 million y ago due to a mammalian-wide inter
15 age of the adaptable nature of J proteins to evolve a multifunctional cochaperone that functions with
16  and bivalve mollusks have also convergently evolved a bivalved shell that displays an apparently mun
17 examined high-altitude deer mice, which have evolved a high capacity for aerobic thermogenesis, to de
18 rvive harsh winter conditions, conifers have evolved a unique but poorly characterized photoprotectio
19 sing link' through which the modern tetramer evolved-a noncooperative homodimer with high oxygen affi
20                              Here we further evolve ABE7.10 using a library of adenosine deaminase va
21  flexible network states that reactivate and evolve across time and experience.
22         Pterosaurs, the first vertebrates to evolve active flight, lived between 210 and 66 million y
23 lterations, a mechanism by which tumor cells evolve, adapt, and resist therapeutics.
24                                 Animals have evolved adaptations to deal with environmental challenge
25       In contrast, stimulus-evoked responses evolved along sloppy dimensions associated with the acti
26 virulence systems and host cell resources to evolve an ingenious scheme for survival and escape.
27 omatis These findings suggest that Chlamydia evolved an oligopeptide transporter to facilitate the ac
28               Mutations that allow tumors to evolve and become resistant to treatment can be readily
29 how protein function and cell morphology can evolve and diversify.
30 t case studies of how assortative mating can evolve and facilitate speciation with gene flow.
31 acorporeal membrane oxygenation continues to evolve and grow, especially when knowledge and familiari
32 s of behavioral plasticity, yet, how animals evolve and modulate functional responses to novel classe
33 d location, influencing how different bodies evolve and their apparent relative surface ages from spa
34  past century, the field of epidemiology has evolved and adapted to changing public health needs.
35 ommunity-wide discussion of how the field is evolving and to help identify areas where a better dialo
36                                           We evolve antibiotic-sensitive populations of the human pat
37  by focal E. coli but also prevented it from evolving antibiotic resistance upon exposure to a beta-l
38 tion genetic processes by which these traits evolve are complex, in part due to interacting ecologica
39 eded to determine how best to implement this evolving armamentarium of treatment options, to elucidat
40  and in vivo These studies highlight an ever-evolving arms race between antiviral factors and viral p
41  be adapted for a broad range of species and evolve as a new omics tool in environmental health asses
42  in this important disease vector originally evolved as a by-product of breeding in human-stored wate
43                  We argue instead that music evolved as a credible signal in at least two contexts: c
44  the last two decades, iridium catalysis has evolved as a valuable tool enabling the stereocontrolled
45                                Proteins have evolved as a variable platform that provides access to m
46 ic surveys function in choanoflagellates and evolved as critical regulators of animal biology.
47          We suggest that the actomyosin ring evolved as one way to improve the efficiency of a core p
48               The designed biosensor hereby, evolves as a promising approach for the recognition of M
49 s helps to explain how mass cell suicide can evolve, as any small benefit to surviving clonemates can
50 that allows male-type aggressive behavior to evolve at least partially independently from courtship b
51 logs outside of the lineage that, even while evolving at a constant rate in a novelty-free manner, ha
52 tion and horizontal gene transfer to counter evolving bacterial host defenses; such arms race dynamic
53 rpetids, which indicates that these features evolved before flight.
54 -minimal surgical pathway" consisted of: (A) evolving best-practices in COVID-19 transmission-reducti
55 e genes during infection without the need to evolve binding sites for antisilencing proteins at each
56     The green alga Chlamydomonas reinhardtii evolved blue light-excited channelrhodopsins (ChR1, 2) t
57 lity in tropical climes led to older, slower-evolving but still species-rich communities.
58 ar functions and developmental processes can evolve by modifying existing genes or creating novel gen
59                        Each surface loop was evolved by infectious cycling in the presence of a helpe
60 ther describes some of the unique strategies evolved by mycobacteria to import nutrients and other pr
61  the oral epithelium, a modified barrier has evolved, called the junctional epithelium (JE).
62  the minimum unit of the cobalt-based oxygen-evolving catalyst.
63                         Gut mucosal microbes evolved closest to the host, developing specialized loca
64 at members of a songbird family-corvids-also evolved complex cognitive skills but a detailed understa
65  library assembles a parent CDN X, where the evolved constituents exhibit catalytic properties to cle
66 lloidal microstructure in stable suspensions evolves continuously during drying.
67 allel genetic evolution, where independently evolved convergent mutations arise in different populati
68 row peduncle, and loss of radial tuberosity, evolved convergently in odontocetes and mysticetes.
69            Consequently, some pathogens have evolved 'core environmental responses' which exploit hos
70 se proteins with local contact topologies to evolve cotranslational folding.
71  well accepted that T4 and other phages have evolved counterdefense mechanisms to protect their genom
72        Virtually all pathogenic viruses have evolved countermeasures to IFN-I restriction, and geneti
73 se mechanisms of bacteria, while phages have evolved covalent modifications as a counterdefense mecha
74                    However, as the infection evolves, COVID(pos) patients distinctively show declinin
75  progression is recognized as a result of an evolving cross-talk between tumor cells and their surrou
76                     This study has therefore evolved current natural marine snow protocols to generat
77                 With information on COVID-19 evolving daily, the public is confronted with a mix of p
78 rting productive frameshifting could rapidly evolve de novo, even in essential genes.
79 this study was to determine whether IRMA may evolve directly into NV.
80 53 represents an example of two genes having evolved disparate outputs while utilizing this shared re
81                        Phages, in turn, have evolved diverse "anti-CRISPR" proteins (Acrs) to counter
82 ot surprisingly, Gram-negative bacteria have evolved diverse posttranslational defense mechanisms to
83 periodic arrangements of crack defects which evolve due to thermal stress under cooling.
84 est that functional brain integration mainly evolves during brain development, with limited changes i
85 owever, in a real ALD process, the interface evolves during the entire ALD oxide deposition due to di
86          Search theory predicts that animals evolve efficient movement patterns to enhance encounter
87 were particularly frequently incorporated by evolving enhancers.
88 pidemiological view postulating that locally evolving environmental V. cholerae contributes to outbre
89             The technique may be tailored to evolve enzymatic activity for a variety of transformatio
90                                 It is a late-evolving epidermal appendage that has the primary functi
91  an issue that becomes more directed in this evolving era of precision medicine.
92 ght remarkable opportunities for the rapidly evolving field of microscopic robotics(1-5).
93 e is the treatment landscape in this rapidly evolving field with an emphasis on drugs in Phase 2 and
94                            MIGS represent an evolving field, and the efficacy and complications of ea
95 lenges that still remain within this rapidly evolving field.
96 ly assess the current status of this rapidly evolving field.
97                                 Here, we (co)evolved five microbial species in replicate polycultures
98        Invasive breast cancer is believed to evolve from non-invasive ductal carcinoma in situ (DCIS)
99 ith a discussion of how patterns of activity evolve from one representation to another, forming dynam
100                The human X and Y chromosomes evolved from a pair of autosomes approximately 180 milli
101 f conserved and divergent genomic characters evolved from a shared ancestral genetic architecture.
102 imal models of cancer, oncologic imaging has evolved from a simple assessment of tumor location and s
103              We show that modern haemoglobin evolved from an ancient monomer and characterize the his
104  body wall resulting from gene co-option, or evolved from an exite (outgrowth; for example, a gill) o
105 1, PanLYK3, PanNFP1, and PanNFP2 These genes evolved from ancient duplication events predating and co
106                 It is hypothesized that Cas1 evolved from casposases, a novel class of transposases.
107                              Treatments have evolved from destruction of the peripheral avascular ret
108                          Staff participation evolved from passive support to professional agency.
109               Over the centuries these tints evolved from raw earths to molecular masterpieces devise
110  hypothesis that the ST-13578 outbreak clone evolved from ST-1504 by recombination.All tested strains
111 ply is regulated in the microvasculature has evolved from viewing erythrocytes (red blood cells [RBCs
112 n how a family of cGAS-STING evasion enzymes evolved from viral proteases through gain of secondary n
113     Secondary acute myeloid leukemias (AMLs) evolving from an antecedent myeloproliferative neoplasm
114                                      Despite evolving from different intellectual traditions, both fr
115 ve seen tremendous progress in recent years, evolving from single sensors to integrated sensing syste
116 isation, and offering an application for the evolved genes as dual-purpose selectable/counter-selecta
117 ffer prospects for tailored design of highly evolved, genetically encoded organophosphorus scavengers
118 d by the level of an implicit mechanism that evolves gradually during learning to produce a temporall
119 e genus Antirrhinum (snapdragons), which has evolved hairy alpine-adapted species or lowland species
120 n, it is unsurprising that many species have evolved hard-wired neural mechanisms to extract motion a
121 measure of neuronal firing and reflects slow-evolving hemodynamic activity that fails to capture the
122                                           In evolving IA patients, 219/294 developed RA; the risk-sco
123  cancer treatments, particularly in recently evolved immune checkpoint inhibition therapy.
124  the best adaptations to one environment may evolve in another.
125 al-life spreading processes, pathogens often evolve in response to changing environments and medical
126 overview and prospectus of how the field may evolve in the coming years is provided.
127              Understanding how these viruses evolve in their natural hosts is key to effective contro
128         Why some AIV lineages but not others evolve in this way is unknown.
129 af and stem hydraulics and growth rates have evolved in a coordinated way in oaks (Quercus) as a resu
130 rted that aerobic growth on citrate (Cit(+)) evolved in an Escherichia coli population during adaptat
131            The field of pacing in Africa has evolved in an uncoordinated way across the continent wit
132 al cell wall cellulose, suggesting expansins evolved in ancient marine microorganisms long before the
133           Crassulacean acid metabolism (CAM) evolved in arid environments as a water-saving alternati
134 ese experiments suggest that bet hedging has evolved in budding yeast.
135 ormal cells in a multicellular organism have evolved in competition between high-level organisms to b
136                                      Animals evolved in complex environments, producing a wide range
137 h as the nanoporous photonic structures that evolved in cuticles of beetles.
138 rationale of how cell surface receptors have evolved in microorganisms to mediate kin discrimination.
139 ignificantly lower within the community they evolved in relative to an allopatric community.
140  lipase-like proteins EDS1, SAG101, and PAD4 evolved in seed plants, on top of existing phytohormone
141  from inhaled pathogens many strategies have evolved in the airways such as mucociliary clearance and
142                                   Amphibians evolved in the Devonian period about 400 Mya and represe
143                 We show that bioluminescence evolved in the last common ancestor of mycenoid and the
144 s, mechanistic examination of how plasticity evolves in a large comparative framework.
145  the thickness of thin liquid films that are evolving in both space and time.
146 e critically review how the field is rapidly evolving in response to the new therapies and questions
147                                       It has evolved independently in many distantly related clades o
148 ns between viruses and parasitoid wasps have evolved independently multiple times, but most of these
149 SS viruses infecting multicellular life have evolved independently on at least three occasions.
150 the same physiological pathway and if dioecy evolved independently.
151  Review, we provide our perspective on these evolving indications for TAVI, discuss relevant availabl
152 e as a window into the subject's dynamically evolving internal beliefs.
153 st of which orbit stars that will eventually evolve into red giants and then into white dwarfs.
154 ectal cancers, we show that individual cells evolve into tumors or aspects of tumors displaying diffe
155 l difficulties at least partially, LP-EM has evolved into a new microscopy method with nanometer spat
156                          Since then DORA has evolved into an active initiative that gives practical a
157 in similar ratios) sex determination systems evolved into one with a dominant factor that results in
158 ated phenotype, which in the advanced stages evolves into fibrosis without detectable inflammation.
159 pectral weight associated to Ag oscillations evolving into stochastic decaying fluctuations.
160 riate drug selection remains crucial in this evolving landscape to derive maximum benefit for the pat
161                                          The evolved lineages acquired numerous parallel mutations, m
162 tional constraint for sauropod species which evolved lower browsing feeding strategies: the antero-do
163                                       Plants evolved lysine motif (LysM) receptors to recognize and p
164 cceleration process associated with the time-evolving magnetization of the hot electron sheath.
165  and pipefish family (syngnathids) that have evolved male pregnancy across a gradient from external o
166                     Here, I propose that the evolved mechanisms of health are distinct from disease p
167 ential for many organisms who have therefore evolved mechanisms to enable survival during hypoxia.
168                                Bacteria have evolved mechanisms to escape neutrophils, including the
169         Despite their complexity, cells have evolved mechanisms to precisely control gene programs in
170                                The brain has evolved mechanisms to prevent catastrophic forgetting of
171                       This article discusses evolving methods to measure myocardial blood flow with p
172                   Our data contribute to the evolving model of tightly controlled proteostasis of the
173 pendicular skeleton, which has been shown to evolve more rapidly in birds, avian cranial morphology i
174 raced the cellular development of a recently evolved morphological novelty, the posterior lobe of D.
175 e incessant host-parasite arms race, viruses evolved multiple anti-defense mechanisms including diver
176 ar cyanobacterium Fischerella thermalis, has evolved multiple times from ancestrally plastic developm
177                       Although pregnancy has evolved multiple times independently among vertebrates,
178                          C(4) photosynthesis evolved multiple times independently from ancestral C(3)
179 ) photosynthesis and annual life history has evolved multiple times, and the resulting diversity in g
180  cells can divide, and eukaryotic cells have evolved multiple ways in which to process branchpoints c
181 he patients' blood can monitor clonality and evolving mutations as a surrogate for tumour biopsy.
182 s disarm their targets emphasizes the highly evolved nature of these processes.
183                   The anuran urostyle, which evolved nearly 200 MYA, is one such structure.
184 ching basal metazoan lineage, which may have evolved neurons and muscles independently from other ani
185 g three highly active amber suppressors, and evolve new amino acid substrate specificities for two pa
186  promising activity, bryostatin 1 is neither evolved nor optimized for the treatment of human disease
187  a felicitous design principle that may have evolved not only to aid the analysis of natural sounds b
188 e controversial, due in part to continuously evolving notions regarding the significance of spontaneo
189 esent in bacteria before aerobic respiration evolved, offer a solution to the stress ROS exert on mol
190 he first and second laser harmonics that can evolve on intra-pulse time-scales.
191 order statistics of observations dynamically evolve over time.
192 led prion protein using a buffer system that evolves over a pH range to accommodate the conflicting p
193 euronal response to conditioned context cues evolves over time in the medial prefrontal cortex, but n
194  prognosis following pancreatectomy for PDAC evolves over time, adjusting for the time the patient al
195                Further analysis should track evolving patterns of responses to subsequent flows of pu
196                                          The evolved peptides have these activities in vitro even in
197 cerol cross-feeding are especially likely to evolve, perhaps because they require less metabolic chan
198 ng new resources can break this trade-off by evolving phenotypic heterogeneity in lag time.
199 e fractional flow reserve has dominated this evolving physiological guidance of coronary intervention
200 d in humans and caused the 2009 pandemic, it evolved polymerase gene mutations that enabled it to mor
201                           Unexpectedly, some evolved populations and clones show apparent declines in
202                 Theory shows that in rapidly evolving populations, such as those of many microbes, ad
203  that test the long-held view that prey have evolved postures that enhance their camouflage, and esta
204     Pterosaurs were the first vertebrates to evolve powered flight(1) and comprised one of the main e
205           To counter this burden, cells have evolved protein quality control (PQC) mechanisms that ma
206 ved role in Drosophila, but it also needs to evolve quickly to restrict telomeric retrotransposons.
207 ly and efficiently mapping these changes are evolving quickly, and it is important to evaluate how us
208 in multiple avian species and show that they evolve rapidly in birds, which is an important indicatio
209  therefore a key seasonal adaptation, and it evolves rapidly with changing environments.
210 terspaced short palindromic repeats)/Cas9 is evolving rapidly.
211 cape of healthcare delivery systems, and our evolving recognition that efforts to prevent cardiovascu
212 n view of the current heterogeneous and fast evolving regulatory landscape worldwide.
213  resistance, understanding of how resistance evolves remains limited.
214 e parasitoid wasp Leptopilina boulardi, they evolved resistance by developing a more reactive cellula
215  therapeutic interventions, directed against evolving resistance.
216  unique life cycles, these arthropods likely evolved robust epigenetic mechanisms that provide sustai
217 g revealed some of the mechanisms that drive evolved sensitivity.
218             We show that leviviruses readily evolve sgl genes and sometimes have more than one per ge
219 ctly into the environment, jawed vertebrates evolved skeletal appendages that drive oxygenated water
220 sites that are further away from the RBS and evolving slower, but also exposed to solvent.
221 NA damage, but instead mount a G2/M DDR that evolves slowly and involves a phosphorylation-independen
222 end, and protect telomeric DNA, which itself evolves slowly in most systems.
223                                Bacteria have evolved sophisticated adaptive immune systems, called CR
224 ldwide morbidity and mortality, and each has evolved specialized strategies to establish and maintain
225                      Poncirus trifoliata has evolved specific adaptation in the C-repeat/DREB binding
226  in both the equilibrium and pre-equilibrium evolving states using a time-resolved approach.
227 a remarkably mature galaxy cluster with both evolved stellar populations in the member galaxies and a
228 onal (i.e., fitness-based) progression of co-evolving STM strains.
229 d metabolic networks de novo, organisms have evolved strategies to neutralize the impact of oxygen th
230 ents (MGEs) compete in dynamic environments, evolving strategies to sense the milieu.
231                                Bacteria have evolved systems dedicated to interbacterial competition.
232                            Some animals have evolved task differentiation among their eyes.
233                    We conclude that recently evolved TE loci such as BANCR may represent potent de no
234 ves and peripheral myelin have fallen behind evolving technical standards.
235 I-guided radiotherapy is a novel and rapidly evolving technology that might enhance the risk-benefit
236                           Indeed, these fast-evolving telomere proteins bind, extend, and protect tel
237 ces in stem cell technology, strategies have evolved that demonstrate the potential to generate new m
238      Being Crabtree-positive, this yeast has evolved the ability to ferment glucose to ethanol and re
239                                           We evolved the deaminase component of ABE7.10 using phage-a
240 V variant that then serves as a template for evolving the next surface loop.
241 created the necessary space in the capsid by evolving the shortest R domain.
242               Virulence mechanisms typically evolve through the continual interaction of a pathogen w
243 uggest that our major psychiatric categories evolved through a complex process involving both observa
244                          Diverse traits have evolved through cis-regulatory changes in genome sequenc
245                 In the clade G1, exCNLs have evolved through recent proliferation and sequence divers
246 generation genome-driven clinical trials can evolve to accelerate our understanding of cancer biology
247 CD) model which predicts that species should evolve to defend territories against heterospecific riva
248 ns are evolutionary puzzles: how do proteins evolve to satisfy multiple functional constraints?
249 ay for them grows, conservation will have to evolve to stay relevant in the age global change-induced
250 ular and anatomical features synergistically evolve to suit an animal's environmental context.
251                    We propose that 53BP1 has evolved to avoid mutagenic repair outcomes and does so b
252 ay in mammals; however, how this pathway was evolved to be functional from its origin is still largel
253   We propose that the EPFL2 signaling module evolved to control the initiation and regular, equidista
254          How the planarian immune system has evolved to cope with these potential pathogens is not we
255 twork in the human brain and how it may have evolved to enable complex speech remain unknown.
256  Our findings suggest that various PSMs have evolved to ensure fast and efficient biofilm formation t
257          We hypothesize that viruses, having evolved to hijack the host cellular machinery for cataly
258 lesion synthesis (TLS) polymerases that have evolved to incorporate nucleotides opposite DNA lesions.
259                   A subpopulation repeatedly evolved to lose the ability to synthesize organosulfurs
260 rier (BBB), a specialized neurovascular unit evolved to maintain brain homeostasis.
261 n elegant strategy that Escherichia coli has evolved to minimize metabolic stress that results from t
262 arget-site resistance (NTSR) mechanisms have evolved to most herbicide classes.
263 ltiple strategies that the immune system has evolved to promote the separation between symbiotic micr
264 that some A. varius populations have rapidly evolved to resist or tolerate Bd infection.
265 lecular machinery for dopamine secretion has evolved to support fast and slow signaling modes, with f
266    The discovery that one bacterial effector evolved to target ATG16L1's engagement in intracellular
267 ost sulfite reductase suggest that phage Fds evolved to transfer electrons to cyanobacterially encode
268 ll surface; hence, diverse secretion systems evolved to transport the hydrophilic molecules to their
269                   However, the virus rapidly evolves to exploit the IFN-alpha response for its replic
270 eatures, and extensive cortical encephalitis evolving to atrophy.
271                                           In evolving to obligate intracellular dependence, Chlamydia
272 comprehensive examples of species adaptively evolving to urbanization.
273 disease 2019 (COVID-19)-associated pneumonia evolve toward severe oxygen dependence (stage 2b) and ac
274             However, most proposed solutions evolve towards a target geometry without considering tim
275  more speciose but also because species have evolved traits that allow them to locally co-occur.
276 the gut, with some symbiotic bacteria having evolved traits to invade the epithelial mucus layer and
277 earch questions relating to this complex and evolving treatment landscape.
278                                           An evolving trend toward the ever-growing market of portabl
279  the course of disease progression (e.g., an evolving tumor).
280 jumping spiders, birds, and butterflies have evolved ultra-black coloration comparable to the blackes
281  present in snakes (SWS1, LWS, and RH1) have evolved under positive selection in elapids, and in sea
282 ion, and those are best suited for organisms evolving under weak selective pressures, such as animals
283 praecox), an important ornamental plant, has evolved unique fragrant aroma and winter-flowering prope
284 e homologous LRR-RKs GSO1/SGN3 and GSO2 have evolved unique peptide binding properties to control dif
285                                          The evolved variants mediated indel formation and base editi
286                       Plant-eating dinosaurs evolved varied feeding strategies.
287 st to the general belief that modern culture evolves very quickly, we show that rates of modern cultu
288 ted aggregate clusters form, grow, fuse, and evolve via internal rearrangement, leading to overall hy
289                Bacteriophage genomes rapidly evolve via mutation and horizontal gene transfer to coun
290 of anatomically modern humans (Homo sapiens) evolved via changes in the thorax, pelvis and limbs.
291         A non-functional and non-genetically evolving viral reservoir along with an HIV-1-specific im
292 p Polistes fuscatus-a wasp that has uniquely evolved visual individual recognition abilities.
293 understood how these reproductive structures evolved, which genes occur de novo in male gametophytes
294                                The reactions evolve with profoundly different kinetics, undergoing au
295       Rapidly-transmitting viruses that have evolved with bat immune systems will likely cause enhanc
296  and diverse microbial community that has co-evolved with its host to perform a variety of essential
297 d phenotyping of cardiovascular diseases has evolved with the application of high-resolution omics sc
298 oid transformation and how clonal complexity evolves with disease progression.
299    The locomotor skeleton of Anolis may have evolved within a subset of possible morphologies that ar
300  Understanding how and why sexual dimorphism evolves would contribute to elucidating the mechanisms u

 
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