ライフサイエンスコーパス: excitatory effect

1 ol and eugenol, whereas linalool produced an excitatory effect.

2 ned the ionic mechanism responsible for BK's excitatory effect.

3 antagonist, alpha-helical CRF, blocked this excitatory effect.

4 nses to these inputs are limited and include excitatory effects.

5 .0 microM) bicuculline produced non-specific excitatory effects.

6 nduced epileptogenesis potentiated LPI's pro-excitatory effects.

7 s indicate that tDCS over the DLPFC has fast excitatory effects, acting on prefrontal and striatal tr

8 y disrupts neuronal activity with an overall excitatory effect and reduces the power of low-frequency

9 The combination of direct excitatory effects and disinhibition induced by activati

10 rexone (NTX) plus fM-nM morphine blocked the excitatory effects and unmasked potent inhibitory effect

11 The serotonin 2C excitatory effects are of lower magnitude and are associ

12 lity cortical and spinal networks, having an excitatory effect at the spinal level and an inhibitory

13 nces cortical and spinal networks, having an excitatory effect at the spinal level and an inhibitory

14 h allyl isothiocyanate and THC mediate their excitatory effects by activating ANKTM1, a member of the

15 clei and the immediately adjacent tegmentum, excitatory effects caused by application of the glutamat

16 ially inhibits GABA release, producing a net excitatory effect during bursts suggesting a mechanism f

17 use these neurons are glutamatergic and have excitatory effects elsewhere, we re-examined the effect

18 al negative feedback loop that restrains the excitatory effect evoked by NMDAR activation.

19 of inhibitory effects on the MAP and SNA to excitatory effects following ARCN stimulation was also o

20 rphine and most other opioid agonists elicit excitatory effects, i.e., APD prolongation, at these low

21 rigger withdrawal, nor did it have a greater excitatory effect in dependent rats.

22 tion of mu opioid receptors (MORs) has a net excitatory effect in the hippocampal formation through i

23 venile rat prefrontal cortex, while exerting excitatory effects in adult rats.

24 lbulimima (GB) sp. leads to psychotropic and excitatory effects in humans(1-4).

25 Serotonin (5-HT) exerts excitatory effects in many brainstem regions involved in

26 rd treatment for neonatal seizures, can have excitatory effects in the neonatal brain, which may wors

27 This excitatory effect is normally present and arises from ce

28 Because NA projects to SON, these excitatory effects may influence the recruitment of inhi

29 ADP, that act together to produce a specific excitatory effect, namely an increased likelihood that a

30 erly compressed DRG in vitro produced potent excitatory effects not observed in control ganglia.

31 Changes from inhibitory to excitatory effect occurred when discharge frequency drop

32 er concentrations (7.5 microM), non-specific excitatory effects occurred.

33 nnels to 5-HT receptors in part mediates the excitatory effect of 5-HT.

34 The excitatory effect of 8-bromo cGMP was blocked by Rp 8-br

35 sion of AVP would lead to an increase in the excitatory effect of a subthreshold dose of AVP on the a

36 These results suggest that the excitatory effect of acetylcholine on the SON neurons is

37 ly at any dose, but did lead to a sensitized excitatory effect of AVP on startle on Day 2 which was n

38 We report a novel excitatory effect of cannabinoid agonists on action pote

39 The excitatory effect of carbachol was blocked by antagonist

40 ransection of the fimbria/fornix blocked the excitatory effect of corticotropin-releasing hormone (CR

41 This excitatory effect of CRF on PAG neurons may lead to acti

42 Infusion of AVP on Day 1 led to a sensitized excitatory effect of CRF on startle on Day 2 which was n

43 ootshocks given on Day 1 led to a sensitized excitatory effect of CRF on startle on Day 2 which was n

44 ootshocks given on Day 1 would sensitize the excitatory effect of CRF on startle tested 48 h later.

45 igand [D-Pen2,D-Pen5]-enkephalin reduced the excitatory effect of DAMGO in the majority of GH3MORDOR

46 The excitatory effect of DAMGO on seven labeled LC neurons w

47 The excitatory effect of DAMGO was also inhibited by pretrea

48 neuronal firing at baseline but enhanced the excitatory effect of forskolin (an activator of adenylyl

49 esthetics act, in part, by inhibition of the excitatory effect of glutamate at the NMDA receptor.

50 that TRPC3 is a key molecular target for the excitatory effect of IgG-IC on DRG neurons.

51 Importantly, MCH blocks the excitatory effect of kisspeptin on vGluT2-GnRH neurons.

52 revealed pacemaker action potentials and the excitatory effect of local glutamate application, which

53 NT connections in vivo, suggesting a reduced excitatory effect of local glutamatergic inputs as a pot

54 Ch, nicotine and pilocarpine potentiated the excitatory effect of Na2S2O4 on [Ca2+]i.

55 prompted us to test the hypothesis that the excitatory effect of noradrenergic inputs on oxytocin an

56 This excitatory effect of opioids on primary afferents can co

57 The excitatory effect of OT on PVT neurons is mimicked by th

58 izes clocks and demonstrates an acute direct excitatory effect of PDF on target neurons to control ne

59 We suggest that the known excitatory effect of PGI2 on baroreceptor and vagal affe

60 n of vPAG astrocytic alpha(1)ARs reduced the excitatory effect of phenylephrine on vPAG(DA) neurons a

61 ect of smoking, thus obscuring a sympathetic excitatory effect of smoking.

62 (nAChR) antagonist mecamylamine blocked the excitatory effect of systemic nicotine on the VTA DA neu

63 r, GABAA receptor pharmacology determined an excitatory effect of the PH on neuroendocrine responses

64 The present data suggest that the excitatory effects of 5-HT on DVN are mediated in part b

65 of strong, direct postsynaptic inhibitory or excitatory effects of 5-HT.

66 T5720) was necessary to block completely the excitatory effects of a ROS donor (tBOOH).

67 Here, we report excitatory effects of AA on a cloned human inwardly rect

68 block (n = 2) or greatly reduce (n = 3) the excitatory effects of alpha,beta-meATP (100 microM, 0.1

69 apine (10.0 mg/kg), in contrast, blocked the excitatory effects of amphetamine on all tested neurons

70 en reduced ongoing activity, and blocked the excitatory effects of ATP.

71 chanism, cocaine sensitizes VTA cells to the excitatory effects of both CRF and orexin-A, thus provid

72 On the other hand, the excitatory effects of both NMDA and AMPA were attenuated

73 o selectively activate mRGCs, simulating the excitatory effects of bright light on this cell type in

74 These excitatory effects of cAMP-PDE inhibitors in naive mice

75 + channels as the primary mechanism of rapid excitatory effects of cocaine and inhibition of centrall

76 y induction of CRF-BP may serve to limit the excitatory effects of CRF in the dentate gyrus.

77 ermine which receptor is responsible for the excitatory effects of CRF on limbic neurons, a selective

78 dogenous opioids may serve to counterbalance excitatory effects of CRF on the LC-norepinephrine syste

79 For a given responsive neuron, the excitatory effects of CRF were reproducible, and there w

80 These results revealed excitatory effects of DA mediated mainly via D2 receptor

81 For this reason, incubation of the excitatory effects of DSs that signal drug availability,

82 Possible mechanisms for excitatory effects of E-2 in the mNTS resulting in depre

83 The excitatory effects of EAA were significantly inhibited i

84 omeostatic mechanisms exist to attenuate the excitatory effects of excess glutamate release.

85 extending the duration of, the developmental excitatory effects of GABA, resulting in divergence of t

86 tivity to ischemia, either by modulating the excitatory effects of glutamate or by modifying the inhi

87 ) receptor, which mediates the post-synaptic excitatory effects of glutamate.

88 nine (L-NOARG)), both the inhibitory and the excitatory effects of L-ARG significantly decreased at h

89 The excitatory effects of metabotropic receptor activation i

90 ted cells which become supersensitive to the excitatory effects of mu-, delta- and kappa-opioid agoni

91 nsor may play an important role in mediating excitatory effects of NO in such trigeminal disorders as

92 butyric acid (GABA) may underlie some of the excitatory effects of opioids in the central nervous sys

93 th the general motivational and the specific excitatory effects of pavlovian cues could be assessed i

94 rumental outcome as well as to the selective excitatory effects of reward-related cues in PIT.

95 also contain glutamate which may mediate the excitatory effects of RVL stimulation on SPNs through th

96 and TRH activate RTN chemoreceptors, and (3) excitatory effects of serotonin and pH are mediated by d

97 Recent studies have shown excitatory effects of serotonin on upper airway motoneur

98 ist ketanserin (10 microm) fully blocked the excitatory effects of serotonin.

99 t alpha-methyl-5-HT (30 microm) mimicked the excitatory effects of serotonin.

100 Coupled with previous demonstrations of excitatory effects of SP on sensory neurons, these resul

101 motion assays were used to study the general excitatory effects of the drugs.

102 -Phe to a D-Phe has a dramatic effect on the excitatory effects of the peptide.

103 vasopressin and provide a mechanism for the excitatory effects of vasopressin at physiological level

104 lon and studied the mechanism underlying the excitatory effects of vasopressin.

105 Both inhibitory and excitatory effects of VD4 stimulation on the PeA(I) and

106 d onset (20-30 s after bolus administration) excitatory effect on 21 of 27 units excited by CRD.

107 ta receptors (GH3MORDOR cells), DAMGO had an excitatory effect on Ca 2+ signaling that was mediated b

108 Despite the excitatory effect on Ca 2+ signaling, DAMGO inhibited Ca

109 Opioids have an excitatory effect on CA1 pyramidal neurons in the hippoc

110 Motilin, a peptide hormone has a direct excitatory effect on circular smooth muscle strips deriv

111 ion in vesicles of axon terminals, and their excitatory effect on cultured hypothalamic neurons sugge

112 re, we report that D-amphetamine also has an excitatory effect on DA cells, which under control condi

113 d that CRF had both a direct and an indirect excitatory effect on DMV neurones via activation of CRF(

114 Our data indicate that glucose had no direct excitatory effect on DMV neurones, but DMV neurones appe

115 increase in tonic inhibition is caused by an excitatory effect on inhibitory interneurons was investi

116 nt negative feedback loop that restrains the excitatory effect on membrane potential and firing activ

117 Only a small, direct excitatory effect on MSNs by Ex-4 was observed, suggesti

118 MDMA had a predominantly excitatory effect on neuronal activity that was positive

119 ory products of cestode larvae have an acute excitatory effect on neurons, which can trigger seizure-

120 eceptors, during parturition and may have an excitatory effect on oxytocin release.

121 It is concluded that CRF has a predominant excitatory effect on PAG neurons.

122 trastriatal neurons in providing a prominent excitatory effect on psychomotor activity.

123 at PACAP-38 exerts a potent and long-lasting excitatory effect on SPNs, leading to an increase of spi

124 l animals, 100 muM carbachol had a transient excitatory effect on spontaneous activity followed by a

125 It was concluded that GES mainly exerted an excitatory effect on T9-T10 spinal neurons with duodenal

126 that bending can also have a slowly-decaying excitatory effect on the CPG's frequency.

127 PMC and SMA, with the latter wielding a more excitatory effect on the diaphragm.

128 higher concentration, CRF had a predominant excitatory effect on the neurons, and at the lower conce

129 ect on the lower esophageal sphincter but an excitatory effect on the upper esophageal sphincter.

130 ents from the vSub to the NAc exert a potent excitatory effect on VTA DA neurons, influencing both DA

131 inspiratory firing patterns associated with excitatory effects on burst timing and pattern.

132 We conclude that Hcrt-2 has excitatory effects on certain SDH neurones, some of whic

133 ten the APD of naive neurons, and evoke only excitatory effects on chronic morphine-treated cells eve

134 Chemokines and gp120 produced excitatory effects on DRG neurons and also stimulated th

135 n the DRN that exert opposing inhibitory and excitatory effects on DRN-5-HT neuronal activity and 5-H

136 cal stimulation induced both suppressive and excitatory effects on neural activity in the DCN of both

137 recordings, we find OT induces long-lasting excitatory effects on neurons in all PVT regions, especi

138 Studies have shown that glutamate elicits excitatory effects on neurons in the PVN through the NMD

139 ogenetic stimulation of this circuit has net excitatory effects on postsynaptic LHb neurons.

140 It was concluded that (1) ACTH exerts excitatory effects on RVLM neurons resulting in pressor

141 5-HT(7) receptors mediated excitatory effects on Shox2 INs from both uninjured and

142 ted whether AVP on Day 1 would sensitize the excitatory effects on startle of CRF given i.c.v. on Day

143 regardless of whether it had suppressive or excitatory effects on these neurons.

144 The excitatory effects on vasomotor neurones, of paraventric

145 effects, whereas the agonist, DOI, produced excitatory effects, on spinal neuronal activity.

146 inhibited striatal and accumbal activity but excitatory effects predominated in both areas.

147 This excitatory effect results from an augmentation of hyperp

148 and reducing [Ca(2+)](e) fails to elicit the excitatory effects seen in the wild-type.

149 The gut peptide ghrelin evoked direct excitatory effects, suggesting these neurons monitor met

150 Cs of the MOB, NA (10 muM) produced a robust excitatory effect that included a slow afterdepolarizati

151 c32a1 (VGAT) in Nts neurons unmasked also an excitatory effect that was blocked by a Nts receptor 1 a

152 mitter but can sometimes produce paradoxical excitatory effects through synaptic networks.

153 time delay between skin stimulation and its excitatory effect was 15.5 msec.

154 ficantly increased by acetylcholine and this excitatory effect was abolished by atropine.

155 For the subset of pairs where a transient, excitatory effect was detected, we use a model-based app

156 The excitatory effect was dose dependent and was often assoc

157 were not different, but the duration of the excitatory effect was slightly longer than that of the i

158 The excitatory effects were blocked by administration of TTX

159 Although the excitatory effects were distributed across S-, N-, and H

160 Excitatory effects were dose-dependent (over the range o

161 These excitatory effects were mediated by the selective muting

162 ue (M-BLU), cystamine (CYS)), L-ARG had only excitatory effects, whereas its effects were only inhibi

163 -BLU) or cystamine (CYS), NO donors had only excitatory effects, whereas their effects were inhibitor

164 inal cord to promote hyperalgesia through an excitatory effect, which is opposite to the well-known i

165 atal and GPe neurons, including biphasic and excitatory effects, which our modeling shows can be expl

166 onic regime, small GABA conductances have an excitatory effect while large GABA conductances show an