ライフサイエンスコーパス: excretion

1 , often exhibit little to no dissolution and excretion.

2 bolism, particularly in the mode of nitrogen excretion.

3 d positively correlated with urinary albumin excretion.

4 ion from nontargeted organs, through urinary excretion.

5 s that were associated with diminished virus excretion.

6 e-dependent increase in fractional phosphate excretion.

7 on rate, glycolytic metabolites, and lactate excretion.

8 racrine and circadian control of electrolyte excretion.

9 ransporter critical for whole-body manganese excretion.

10 ogens, promoting pathogen clearance by urine excretion.

11 applies to the control of renal electrolyte excretion.

12 anism of secretin-induced urinary HCO(3) (-) excretion.

13 ormation, renal excretion, and hepatobiliary excretion.

14 r molecules tending toward passive or active excretion.

15 GFR and glomerular protein filtration affect excretion.

16 irectly contribute to reduced urinary sodium excretion.

17 senical species (DMAs), facilitating urinary excretion.

18 excess and impaired systemic and biliary Mn excretion.

19 ning decline and change in duration of aMT6s excretion.

20 plasma protein binding and extensive biliary excretion.

21 absorption and hepatobiliary and intestinal excretion.

22 mainly due to a reduction in urinary albumin excretion.

23 positively correlated with fecal coprostanol excretion.

24 inimal Mn excess despite impaired biliary Mn excretion.

25 r (LDH5) stiripentol reduces urinary oxalate excretion.

26 etabolite concentrations as well as temporal excretion.

27 ry hyperoxaluria reduced the urinary oxalate excretion.

28 study compliance via para-aminobenzoic acid excretion.

29 SMX and its metabolites, likely due to plant excretion.

30 ne acrophase, morning offset and duration of excretion.

31 hepatic oxalate production and urine oxalate excretion.

32 acutely activates NCC to modulate renal NaCl excretion.

33 rimary and reduced secondary fecal bile acid excretion.

34 ficant evidence of reduced extra-renal urate excretion.

35 ecules with fast blood clearance and urinary excretion.

36 h well-established neuroendocrine control of excretion.

37 biotin inhibited organ uptake and increased excretion.

38 nary angiotensinogen and beta2-microglobulin excretion.

39 L) plays a key role in urinary acid and NaCl excretion.

40 randial PG through increased urinary glucose excretion.

41 ion, lipid droplet content, and triglyceride excretion.

42 charide (GB1107 surrogate) showed no sign of excretion.

43 liver and thereby to decrease biliary lipid excretion.

44 ermeability changes produce large changes in excretion.

45 n of [(11)C]13 and hepatobiliary and urinary excretions.

46 24HDR) with intake derived from 24-h urinary excretion (24HUE).

47 5.6]), living in Lome (2.8 [1.1-7.1]), HSV-2 excretion (26.7 [2.9-244.3]), C. trachomatis (11.7 [2.3-

48 o associated with increasing urinary protein excretion-a strong prognosticator of adverse renal outco

49 he absorption, distribution, metabolism, and excretion (ADME) data showed relatively poor aqueous sol

50 the absorption, distribution, metabolism and excretion (ADME) of metabolites.

51 he absorption, distribution, metabolism, and excretion (ADME) profile of the series were optimized re

52 ng absorption, distribution, metabolism, and excretion (ADME) profile while being devoid of a peptido

53 ro absorption, distribution, metabolism, and excretion (ADME) profiles were subjected to in vivo proo

54 NA absorption, distribution, metabolism, and excretion (ADME) properties are lacking.

55 vo absorption, distribution, metabolism, and excretion (ADME) properties of 24 yielded a preclinical

56 nd absorption, distribution, metabolism, and excretion (ADME) properties, further reflected in the en

57 ro absorption, distribution, metabolism, and excretion (ADME) properties, which was progressed into p

58 nd absorption, distribution, metabolism, and excretion (ADME) properties.

59 ot respond with increased urinary HCO(3) (-) excretion after stimulation with secretin and often pres

60 , but only subtle alterations of renal urate excretion and ABCG2 abundance.

61 ctance regulator (CFTR) in urinary HCO(3) (-)excretion and applied it in the patients before and afte

62 nvoluted tubule (DCT) regulates urinary NaCl excretion and BP.

63 tary phosphorus intake or urinary phosphorus excretion and BP.

64 shared between urinary sodium and potassium excretion and cardiovascular traits.

65 Fractional Na(+) excretion and cortical oxygen tension were lower and ren

66 Oocyst excretion and diarrhea severity were observed daily, and

67 icant associations were detected between ENL excretion and fecal microbiome measured at baseline and

68 uation to high protein, yielding higher urea excretion and increased phenylalanine oxidation rates (P

69 The higher dose lowered urinary ammonium excretion and increased serum bicarbonate more than the

70 s and the hindgut perform essential roles in excretion and ionic and osmotic homeostasis.

71 ssociated with lower urinary nitrite/nitrate excretion and markedly increased urinary PGE(2) excretio

72 ss the association between usual 24-h sodium excretion and measures of adiposity among US adults.

73 riant in Exon-14 that was associated with DA excretion and multiple other renal traits indicating ple

74 takes into consideration changes in albumin excretion and other risk factors in addition to HbA(1c)

75 rious physiological processes including acid excretion and pH regulation.

76 t on Npt2a-null mice, but promoted phosphate excretion and reduced phosphate levels in normophophatem

77 osphate levels by increasing renal phosphate excretion and reducing 1,25-dihydroxyvitamin D3 [1,25(OH

78 ected to grazers, sloppy feeding (as well as excretion and respiration), viruses and viral lysate res

79 tegy to enhance the analysis of radionuclide excretion and retention kinetics.

80 This interplay between metabolite excretion and their chemotaxis-dependent reutilization i

81 romotes osmotic diuresis via urinary glucose excretion and therefore, might offer a novel treatment o

82 day 1 identified 24-hour urinary creatinine excretion and TIMP-2/mOsm as significant predictors of f

83 f drug absorption, distribution, metabolism, excretion and toxicity through fluidically coupled organ

84 ies, namely, metabolic transformation, renal excretion, and hepatobiliary excretion.

85 However, changes in SNGFR can alter protein excretion, and hyperfiltration with glomerular leak can

86 1) R from the brush border, decreased sodium excretion, and increased oxidative stress and BP in C57B

87 rallel, it suppressed urinary norepinephrine excretion, and induced c-Fos expressions in the area pos

88 ular filtration rate (GFR) and urine albumin excretion, and kidney injury was evaluated by histopatho

89 or models were used to estimate usual sodium excretion, and multiple linear and logistic regression m

90 Unfortunately, liver accumulation, biliary excretion, and no tumor uptake were observed on planar s

91 inal 0-2 scale: hepatic enhancement, biliary excretion, and the signal intensity in the portal vein.

92 ess is associated with increased free proton excretion, and thus with a decline in the kidney's acid

93 ood, low hepatobiliary excretion, fast renal excretion, and very low uptake of (18)F activity in bone

94 Urinary sodium and potassium excretion are associated with blood pressure (BP) and ca

95 Dynamic simulations of excretion are generally consistent with the results of t

96 ts absorption, distribution, metabolism, and excretion are poorly understood.

97 erular filtration rate and urinary potassium excretion associated with hyperkaliemia at day 3.

98 timulates ammoniagenesis that increases acid excretion but also leads to ammonia-induced complement a

99 nclude adaptive responses that increase acid excretion but lead to a decline in kidney function.

100 eved by a combination of managing intake and excretion but sometimes both drinking and urination are

101 k appears also to raise E2, E3, and 16ketoE2 excretion, but future studies need to confirm these asso

102 e immediate benefit of increased kidney acid excretion, but their chronic upregulation promotes infla

103 ced by a 27-fold increase in urinary glucose excretion by 3 hours (P<0.0001).

104 Vasopressin regulates renal water excretion by binding to a G(alpha) s-coupled receptor (V

105 racellular phosphate regulates its own renal excretion by eliciting concentration-dependent secretion

106 Water excretion by the kidney is regulated by the neurohypophy

107 Inadequate urinary phosphate excretion can lead to severe hyperphosphatemia as in tum

108 -fold increase in efficiency of urinary iron excretion compared to intravenous injection.

109 advantages of (18)F labeling and low urinary excretion compared with (68)Ga-PSMA-11.

110 24 hr urine albumin excretion correlated highly with decreasing podocyte den

111 During diuretic treatment, higher PGE2 excretion correlated with lower free water clearance, an

112 ting that early increases in urinary albumin excretion could be predictive of adolescents with T1DM w

113 roposed model was calibrated against urinary excretion data for 42 drugs, and the utility for DICN pr

114 ptake of each chemical and was compared with excretion data from a prior human subject study with the

115 Stiripentol for several weeks: urine oxalate excretion decreased by two-thirds.

116 l, both nanoparticles led to higher consumer excretion, despite contrasting particle stability and ph

117 e sampled for evidence of virus exposure and excretion during a prospective nine year serial cross-se

118 anism of secretin-induced urinary HCO(3) (-) excretion, explain metabolic alkalosis in patients with

119 rance kinetics from blood, low hepatobiliary excretion, fast renal excretion, and very low uptake of

120 Here, we dynamically profile the uptake and excretion fluxes of a liver cancer cell line (HepG2) and

121 red parasite strain totally prevented oocyst excretion following infection with wild-type T. gondii,

122 ight into the importance of intestinal urate excretion for serum urate homeostasis.

123 is important to correct 24-h urinary sodium excretion for within-person variance.

124 C-21 dose-dependently increased urine Na(+) excretion from 0.023+/-0.01 to 0.064+/-0.02, 0.087+/-0.0

125 Dietary sodium restriction reduced sodium excretion from 160 to 64 mmol per day.

126 Transition of albumin excretion from normal to microalbuminuria, a 5-fold incr

127 and thus with a decline in the kidney's acid excretion function, which could potentiate the risk of r

128 Urinary TX metabolite (TXM) excretion, gastrointestinal tolerance, and ET-related sy

129 ney-specific biodistribution and rapid renal excretion (>80% injected dose in 4 h), compared to nativ

130 ology and function, BP, sodium and potassium excretion, gut microbiome, flow cytometry, catecholamine

131 atic manganese uptake for subsequent biliary excretion has been proposed as the underlying disease me

132 id in osmoregulation, acid-base balance, and excretion have been well documented.

133 Increased urinary oxalate excretion (hyperoxaluria) promotes the formation of calc

134 tify 50 loci for sodium and 13 for potassium excretion in a large-scale genome-wide association study

135 t NTCP inhibition still promoted cholesterol excretion in Abcg8(-/-) mice.

136 predicted from data for 24-h urinary sodium excretion in adult kidney transplant recipients in 1992-

137 support an important role for ABCG2 in urate excretion in both the human kidney and intestinal tract,

138 thus links glutamine addiction to glutamate excretion in cancer and points toward potential drug tar

139 high AGE formation in diabetes and decreased excretion in CKD or by dietary modifications in these di

140 f first-pass drug absorption, metabolism and excretion in humans-using computationally scaled data fr

141 stration reduced significantly urine oxalate excretion in rats.

142 h fecal coprostanol and total neutral sterol excretion in recipient mice.

143 of the regulation and dysregulation of water excretion in the kidney.

144 such as bioconversion, bioaccumulation, and excretion in vivo.

145 cholesterol transport genes for its biliary excretion, including scavenger receptor class B member 1

146 These adaptations included decreased BA excretion, increased pool size, altered BA composition,

147 n humans and their elimination and potential excretion into human milk are not yet fully understood.

148 difficile infection because of their biliary excretion into the gastrointestinal tract and disruption

149 Twenty-four hour urine oxalate excretion is an inaccurate measure for endogenous oxalat

150 Higher usual sodium excretion is associated with overweight/obesity and cent

151 This suggests that impaired hepatobiliary excretion is not the primary cause for manganese overloa

152 hosphate (ATP), but the reason for glutamate excretion is unclear.

153 hyperfiltration restores sodium and chloride excretion it imposes added physical stress on the filtra

154 ysis shows that urinary sodium and potassium excretion loci are over-represented in behavioural respo

155 er, despite the continuously elevated solute excretion, long-term osmotic diuresis does not occur in

156 rphic mouse (kl/kl) with impaired urinary Pi excretion, low autophagy, and premature organ dysfunctio

157 se in the percentage of subjects with iodine excretion <100 ug/24 h (P < 0.001) was observed, without

158 Persistently increased urinary phosphate excretion maintains serum phosphate levels within the no

159 systemic circulation and prevent its urinary excretion, making difficult its detection and quantitati

160 port into bile is a major route of manganese excretion, manganese levels in the brain, blood, and liv

161 tress and that they involve several distinct excretion mechanisms, including direct plasma membrane t

162 Reduced net acid excretion (NAE) capacity indicates a decrease in renal f

163 iency uptake kinetics and fractional urinary excretion of 0.025%, whereas albumin and alpha(1) -micro

164 netics and 50-fold higher fractional urinary excretion of 1.15%.

165 Urine excretion of 6 AngII-regulated proteins was quantified u

166 n studies revealed significant hepatobiliary excretion of [(18)F]FGlc-FAPI; however, small-animal PET

167 tes insipidus is a syndrome characterized by excretion of abnormally large volumes of dilute urine.

168 , the absence of Gpr116 results in a primary excretion of acid in KO mouse urine, leading to mild met

169 Urinary excretion of all other analytes was unchanged between th

170 reversible leukoencephalopathy and a urinary excretion of alpha-ketoglutarate (alphaKG) that was mark

171 Urine excretion of AngII signature proteins correlated strongl

172 ncreases tissue exposure in mice and reduces excretion of ASO in urine, histological review of skelet

173 ng in increased hepatic production and fecal excretion of BAs, reduced hepatic cholesterol, and decre

174 Our results indicate that the urinary excretion of beta(2) -m and RBP4 differs from that of al

175 i compared with normal controls, and urinary excretion of both cathepsins was significantly greater i

176 d secondarily systemically followed by renal excretion of byproducts were the predominant elimination

177 Total urinary and fecal excretion of catabolites accounted for <5% of each of th

178 of cell wall extensibility via the polarized excretion of cell wall-loosening compounds at the tip.

179 t of ADPKD patients, lower levels of urinary excretion of citrate, an endogenous inhibitor of calcium

180 higher (p < 0.001, p < 0.001), and the fecal excretion of deoxycholic (p < 0.03, p < 0.02) and chenod

181 thesis, production of queuine/queuosine, and excretion of dietary mercury.

182 2) are critically involved in absorption and excretion of diverse cationic drugs.

183 Cow milk consumption increases urinary excretion of E1 in humans.

184 The analysis also quantified urinary excretion of ECM proteins and peptides.

185 Urinary excretion of ECM-derived peptides was enhanced in cFSGS,

186 We have known for decades that excretion of electrolytes is dependent on time of day, w

187 Urine excretion of ferulic acid was higher (p < 0.001, p < 0.0

188 0.6 +/- 16.0%; P = 0.04), indicating partial excretion of inert gas across small pulmonary arteries.

189 ust ingestion estimates were made from fecal excretion of inert tracers with corrections for dietary

190 e, secretory pathway-mediated assemblage and excretion of infective particles represent appealing tar

191 e external calcite structure produced by the excretion of interlocking plates by the phytoplankton co

192 ferences in urine KP activity and fractional excretion of KP metabolites.

193 eability, measured by the urinary fractional excretion of lactulose-to-mannitol ratio (LMR) at recrui

194 nsipidus (DI) is a disorder characterized by excretion of large amounts of hypotonic urine.

195 per mille) during the day at high pH and the excretion of lighter Zn isotopes (-0.4 per mille < Delta

196 lunted this response and inhibited efficient excretion of lodged crystals.

197 Urinary excretion of LTE(4) was measured by ELISA.

198 Urinary excretion of mammalian-microbial co-metabolites hippurat

199 tubule epithelial cells, mediates the renal excretion of many clinically important drugs.

200 in adsorption, distribution, metabolism and excretion of metabolites and pharmaceuticals, as well as

201 concentration ability, and augmented urinary excretion of Na(+) and urea in both mutant mice.

202 Excretion of naphthalene-derived metabolites was also ac

203 Excessive excretion of oxalate in the urine results in the formati

204 ominant males differentially upregulated the excretion of particular MUPs, including the pheromone MU

205 We found urinary excretion of pentosidine was increased ca. twofold in pa

206 in silico analysis did not identify enhanced excretion of peptides derived from cathepsin B or C.

207 ), imparting high biocompatibility and >90 % excretion of QDs within 2 weeks of intravenous administr

208 on is associated with an increase in urinary excretion of sex steroid hormones and their metabolites

209 Reduced fecal excretion of short-chain fatty acids (including butyrate

210 used a nonsignificant increase in fractional excretion of sodium at day 3, which was absent at week 6

211 diabetic controls, this increased fractional excretion of sodium from ~1% to ~25% of the filtered loa

212 Fractional excretion of sodium increased significantly with empagli

213 lozin monotherapy versus placebo (fractional excretion of sodium, 1.2+/-0.7% versus 0.7+/-0.4%; P=0.0

214 t in combination with bumetanide (fractional excretion of sodium, 5.8+/-2.5% versus 3.9+/-1.9%; P=0.0

215 xalate stones) had a 40% decrease in urinary excretion of succinate, a 35% increase in serum succinat

216 ration of aromatic compounds to optimize the excretion of such products while keeping precursor molec

217 ansgenic biosensor to visualize the vascular excretion of the genetically tagged plasma protein DBP-E

218 Herein we report urinary excretion of the latter analytes and related fractional

219 or serum neutralizing antibody) and/or stool excretion of the vaccine strain, stratified by HBGA stat

220 f 19 kidney transplant recipients, the urine excretion of these 6 proteins was significantly lower fo

221 Our findings suggest that excretion of these biomarkers may be influenced by chang

222 To monitor the excretion of these garlic metabolites in a larger cohort

223 the intensity of absorption, metabolism and excretion of these pigments.

224 odel yields segmental deliveries and urinary excretion of volume and key solutes that are consistent

225 ea transporter (UT) inhibition increases the excretion of water and urea, but the effect on uremic ca

226 Remarkably, fractional excretions of 6 lysine and arginine-derived glycation fr

227 We conclude that higher fractional excretions of glycation adducts are potential biomarkers

228 trophic interactions, in which the metabolic excretions of one species are the primary resource for a

229 s estradiol (E2), estriol (E3), and 16ketoE2 excretion only increased after semiskimmed milk consumpt

230 contrast, C-21 did not increase urine Na(+) excretion or renal interstitial cGMP in SHR.

231 increases in urine volume (p < 0.01), sodium excretion (p < 0.01), and creatinine clearance (p < 0.00

232 e at delivery (p = 0.049), increased protein excretion (p = 0.01), more extreme laboratory derangemen

233 nd absorption, distribution, metabolism, and excretion parameters as well as mass spectrometry experi

234 The excretion pathomechanisms of SARS-CoV-2 are actually unk

235 at 1 h after injection), indicating a renal excretion pathway.

236 bariatric surgery can influence absorption, excretion, pharmacokinetics, and pharmacodynamics of var

237 .g. immunoglobulin G [IgG]), urinary nephrin excretion (podocyte injury) and serum levels of the solu

238 Honeydew is the excretion product of phloem-feeding hemipteran insects s

239 educed PT length can account for the urinary excretion profile in LS.

240 Whereas the fast excretion profile of the TD139 surrogate indicated that

241 Altered PK, and excretion profiles of acetaminophen were observed in ant

242 with diabetes duration, most recent albumin excretion rate (AER), updated mean triglycerides, baseli

243 as accurate by comparing measured creatinine excretion rate (CER) to CER estimated using a 4-variable

244 ar filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and classify

245 The mean urinary albumin excretion rate after washout was 40% (95% CI, 0 to 80) h

246 l-based GFR per year and the urinary albumin excretion rate after washout.

247 -density lipoprotein, triglycerides, albumin excretion rate, and DCCT/EDIC mean updated hemoglobin A1

248 oparticles increased nitrogen and phosphorus excretion rates more than copper nanoparticles, but over

249 We tested this hypothesis by measuring the excretion rates of nitrogen and phosphorus of Physella a

250 h nitrogen and phosphorus had overall higher excretion rates than ones in ambient (no nutrients added

251 each test beverage due to decreased urinary excretion rates, 2) glucose (glu)- and amino acid (AA)-b

252 Due to the increasing use and high excretion rates, high quantities of the antidiabetic dru

253 ate for older adults due to attenuated urine excretion rates.

254 ynamics, substrate conversion and production excretion rates.

255 , raw bovine milk, and Ascaris suum nematode excretions), recovering size and stiffness distributions

256 drugs (e.g. distribution, circulation time, excretion, redox properties) is also mentioned.

257 entally that partial inhibition of glutamate excretion reduces cell growth.

258 The kidneys demonstrated high excretion-related retention, whereas all other tissue de

259 ve increased glucose consumption and lactate excretion relative to the same cells in the quiescent st

260 omparative metabolomics of plant tissues and excretions revealed that ascr#18 is converted into short

261 tro absorption, distribution, metabolism and excretion screening approach, analogues were synthesized

262 the single most abundant protein in T. muris excretions/secretions, is non-immunogenic during infecti

263 co absorption, distribution, metabolism, and excretion studies demonstrated that the incorporation of

264 nd absorption, distribution, metabolism, and excretion testing.

265 d with Stiripentol had a lower urine oxalate excretion than control patients.

266 ave been widely shown to benefit from diatom excretions that accumulate within the microenvironment s

267 articipants in the lowest quartile of sodium excretion, the adjusted prevalence ratios in the highest

268 mal level of creatinine in the serum and its excretion through urine in apparently healthy individual

269 h has found animal-mediated nutrient supply (excretion) to be highly predictable based on allometric

270 The highly heritable DA excretion trait is substantially influenced by a previou

271 as calculated as the ratio of urinary iodine excretion (UIE) to total iodine intake.

272 sis of undiluted sweat immediately after its excretion using a flow-through glucose biosensor.

273 study (GWAS) on urinary sodium and potassium excretion using data from 446,237 individuals of Europea

274 ectrometry (LC-MS/MS) and deduced fractional excretion using reported plasma levels and urinary and p

275 f the latter analytes and related fractional excretion values, exploring the link to MA and early dec

276 le absorption, distribution, metabolism, and excretion values.

277 Mean urinary ammonium excretion was 25% lower and serum bicarbonate concentrat

278 The ratio between urinary and fecal excretion was also altered in antibiotic treated animals

279 ed >=1 24-h urine sample, and urinary solute excretion was analyzed.

280 Fecal oxalate excretion was enhanced in wild-type mice with CKD.

281 Fractional Na(+) excretion was increased and oxygen consumption reduced i

282 Urinary pregnanediol glucuronide excretion was not significantly affected.

283 Cumulative urinary d3-alpha-CEHC excretion was not significantly changed by any intervent

284 A 1000-mg/d higher sodium excretion was significantly associated with 3.8-units hi

285 ration and tubular uptake to urinary protein excretion, we developed a mathematical model of protein

286 Consistent with its role in Pi excretion, we found that dietary Pi induces MFS2 express

287 chloride, potassium, phosphate, and calcium excretion were assessed in response to the Npt2a inhibit

288 , and urinary prostacyclin metabolite (PGIM) excretion were measured at randomization and after 2 wee

289 enin concentration, and urinary endothelin-1 excretion were similar between knockout and control mice

290 ronic nanoparticle exposure doubled nutrient excretion when compared to the control.

291 ease in biliary cholesterol and phospholipid excretion whereas biliary bile salt output and bile salt

292 significant increase in urinary estrone (E1) excretion, whereas estradiol (E2), estriol (E3), and 16k

293 retion and markedly increased urinary PGE(2) excretion, whereas GFR, plasma renin concentration, and

294 re different between nitrogen and phosphorus excretion, which could have implications for the resulti

295 essin antagonists) predominantly cause water excretion, which increases the osmolality of the circula

296 -I [TSP1]) and hypothesized that their urine excretion will correlate with IFTA in kidney transplant

297 ic acid nephropathy, and elevated beta(2) -m excretion with increased single nephron glomerular filtr

298 functionalization layer facilitated 90% ErNP excretion within 2 weeks without detectable toxicity in

299 minated completely through hepatic and renal excretion within four weeks of injection with no evidenc

300 f the RNA nanoparticle were cleared by renal excretion within half hour after systemic injection.