ライフサイエンスコーパス: exertional

1 647]; p < 0.0001) and 10.5% increase in non-exertional (active) activity (15,366 [14742, 15990] vers

2 ment and determine optimal time to return to exertional activities (eg, school, sports) is lacking.

3 e care, mortality reaches 26.5% and 63.2% in exertional and classic heatstroke, respectively.

4 .e., quinapril) prevents transient ischemia (exertional and spontaneous) in patients with coronary ar

5 was greater in stable (48.5%) and crescendo exertional angina (48.8%) than in rest angina (30.4%).

6 te myocardial infarction (n = 916) or stable exertional angina (n = 468).

7 alpha-actin and Lp(a) areas in the crescendo exertional angina (r = 0.62, p < 0.01).

8 y patients (mean age, 65.2+/-7.6 years) with exertional angina and coronary artery disease underwent

9 heart disease (IHD), myocardial ischemia and exertional angina are caused by obstructive atherosclero

10 either acute myocardial infarction or stable exertional angina between October 2001 and December 2003

11 -4.3 years) with a positive exercise ECG and exertional angina completed the protocol.

12 enter study, 41 men with reproducible stable exertional angina due to ischemic CAD received vardenafi

13 Severe aortic stenosis (AS) can manifest as exertional angina even in the presence of unobstructed c

14 arctions and 419 adults with incident stable exertional angina who had baseline eGFRs </=130 ml/min/1

15 tic, but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arr

16 Compared with patients with incident stable exertional angina, patients with incident acute myocardi

17 A total of 178 patients with stable exertional angina, unsuitable for standard revasculariza

18 7%; P < 0.001) than patients presenting with exertional angina.

19 relatively stable coronary disease, such as exertional angina.

20 nts (50% men, mean age 66 +/- 10 years) with exertional anginal symptoms undergoing diagnostic angiog

21 o cardiac hemodynamics and determine whether exertional arterial stiffening can be mitigated by inorg

22 The perceived intensity of exertional breathlessness (i.e. dyspnoea) is higher in o

23 e severity of airflow limitation in terms of exertional breathlessness and mortality in the general U

24 Exertional breathlessness, the principal symptom of HF,

25 0.55) (SOE, moderate); most studies examined exertional breathlessness.

26 IC was defined as the presence of exertional calf discomfort that was relieved with rest.

27 Intermittent claudication, consisting of exertional calf pain that does not begin at rest and tha

28 le for heart-arterial coupling in modulating exertional capacity in the elderly, suggesting a potenti

29 The SAQ scores for exertional capacity, anginal stability and frequency, tr

30 dobutamine, indicating dysregulation of post-exertional cardiovascular function.

31 a 55 year old female who presented with non-exertional chest pain in the setting of an emotional str

32 In middle-aged men, exertional chest pain is a strong indicator of major cor

33 All patients with an episode of unstable exertional chest pain or chest pain at rest presumed to

34 in, nonexertional chest pain, or angina (Q) (exertional chest pain) on each occasion.

35 % of the screening forms included history of exertional chest pain, dyspnea, or fatigue; familial hea

36 d benign, though it has been associated with exertional chest pain, which may mimic acute coronary sy

37 oronary syndrome in patients presenting with exertional chest pain.

38 rtional symptoms (group 1) and 52 (24%) with exertional chest pain/syncope (group 2).

39 Chronic exertional compartment syndrome (CECS) is a condition oc

40 Rarely, an exertional compartment syndrome may become acute.

41 Patients with atypical exertional complaints require careful clinical and physi

42 manifest as multiple types, with general and exertional components.

43 Susceptibility to exertional cramps and rhabdomyolysis in myophosphorylase

44 plaque occurred in 18 (72%) of 25 men in the exertional-death group and 47 (41%) of 116 men in the re

45 aques in the coronary arteries of men in the exertional-death group was 1.6 (1.5) and in the at-rest

46 ater for thermal burns, oral rehydration for exertional dehydration, pediatric tourniquet use, and me

47 therapy in patients with moderate resting or exertional desaturation (SpO2 of 89% to 93%).

48 or function in patients with isolated severe exertional desaturation remains inconclusive, prompting

49 minant families with epilepsy and paroxysmal exertional dyskinesia (PED).

50 nt in 74% of patients, with symptoms such as exertional dyspnea (14%) and chronic cough (9%).

51 Most commonly reported symptoms were exertional dyspnea (78%) and fatigue (73%).

52 I] = 0.9-6.6%), a 1.6-fold increased odds of exertional dyspnea (95% CI = 1.3-1.9), a 1.5-fold increa

53 ient selection, including drug treatment for exertional dyspnea (beta-blockers, verapamil, disopyrami

54 The most common clinical presentation was exertional dyspnea (n=17; 65%), whereas 8 (31%) patients

55 e examined consecutive patients with chronic exertional dyspnea (New York Heart Association class II

56 rial, 150 subjects (age 67 +/- 9 years) with exertional dyspnea (New York Heart Association functiona

57 agm muscle weakness and its association with exertional dyspnea 2 years after hospitalization for COV

58 d persistent CCS symptoms such as fatigue or exertional dyspnea after convalescence and healthy contr

59 Affected patients often experience severe exertional dyspnea and debilitating fatigue, as well as

60 Patients with exertional dyspnea and diastolic dysfunction on echocard

61 previously healthy soldiers with unexplained exertional dyspnea and diminished exercise tolerance aft

62 t children with asthma may falsely attribute exertional dyspnea and esophageal reflux to asthma, lead

63 -induced laryngeal obstruction (EILO) causes exertional dyspnea and is important for its effect on qu

64 ] age 70 +/- 12 years; 21 women, 9 men) with exertional dyspnea and negative exercise test results, a

65 The authors studied individuals with chronic exertional dyspnea and preserved ejection fraction who u

66 s with moderate to severe heart failure that exertional dyspnea can be alleviated by improving muscle

67 pacemakers were implanted in 9 patients with exertional dyspnea caused by HHCO.

68 Exertional dyspnea disproportionate to pulmonary functio

69 iaphragm and inspiratory muscle weakness and exertional dyspnea in individuals with long COVID.

70 dentify a potential treatment for persisting exertional dyspnea in long COVID and provide a possible

71 Exertional dyspnea is a frequent limiting symptom in pat

72 Amelioration of exertional dyspnea is achieved by other mechanisms, such

73 After heart transplantation, exertional dyspnea is markedly diminished.

74 Exertional dyspnea or chest pain, prior limitation from

75 Thirty additional participants without exertional dyspnea served as controls.

76 th PRISm, lower exercise capacity and higher exertional dyspnea than healthy controls were mainly exp

77 with heart failure are frequently limited by exertional dyspnea that may be due to the increased work

78 ith persistent diaphragm muscle weakness and exertional dyspnea were randomized to 6 weeks of IMT or

79 to severe AS, such as exercise intolerance, exertional dyspnea, and syncope, are associated with a 1

80 HF symptoms, especially exertional dyspnea, are common in ARVC/D; yet, classic l

81 Exertional dyspnea, chest pain, palpitations, and ankle

82 D-19-related persisting symptoms (resting or exertional dyspnea, cough, fatigue) underwent same-day E

83 gm muscle weakness might underlie persistent exertional dyspnea, despite normal lung and cardiac func

84 ssive disease that causes progressive cough, exertional dyspnea, impaired quality of life, and death.

85 ars of age) with stage C heart failure (HF) (exertional dyspnea, New York Heart Association functiona

86 to our hospital after developing progressive exertional dyspnea.

87 manifests with symptoms such as fatigue and exertional dyspnea.

88 tical activation were potentially related to exertional dyspnea.

89 30 individuals reported relevant persistent exertional dyspnea.

90 She has symptoms of fatigue, achiness, and exertional dyspnea.

91 Patients presenting with exertional dyspnoea and signs of diastolic dysfunction (

92 of intermittent chest pain, palpitations and exertional dyspnoea.

93 ferent cardiovascular diseases, referred for exertional dyspnoea.

94 on fraction >50%, diastolic dysfunction, and exertional E/e' >13), excluding those with ischemic hear

95 improvements in peak oxygen uptake (VO2) and exertional E/e' ratio, and secondary outcomes were impro

96 Exertional echocardiography may indicate patients with i

97 All patients demonstrated a significant exertional effort as demonstrated with the mean peak exe

98 r daily activities in addition to supervised exertional exercises.

99 of pain, fatigue, cognitive dysfunction and exertional exhaustion.

100 es (fatigue subtypes): (1) high general/high exertional fatigue (18%), (2) high general/low exertiona

101 fatigue (27%), (3) moderate general/moderate exertional fatigue (20%), and (4) low/no general and exe

102 ertional fatigue (18%), (2) high general/low exertional fatigue (27%), (3) moderate general/moderate

103 al fatigue (20%), and (4) low/no general and exertional fatigue (35%).

104 pulmonary exercise testing and evaluation of exertional fatigue and dyspnea over a period of one to f

105 d regurgitation (TR) frequently present with exertional fatigue and dyspnea, but the hemodynamic basi

106 woman with recurrent lung cancer and severe exertional fatigue and dyspnea, illustrate how dyspneic

107 literation (HHCO) can result in debilitating exertional fatigue and dyspnea.

108 scle glycogen depletion results in increased exertional fatigue and reduced endurance.

109 ly exercising skeletal muscle contributes to exertional fatigue in HF.

110 igue were mostly concordant in severity, and exertional fatigue only occurred in conjunction with gen

111 We measured exertional fatigue using the Modified Medical Research C

112 Within subtype, general and exertional fatigue were mostly concordant in severity, a

113 associated with higher levels of general and exertional fatigue.

114 (HFpEF), but it remains unknown if restoring exertional heart rate through atrial pacing would be ben

115 ce (NATA-IATF) released guidelines to reduce exertional heat illness (EHI) among U.S. high school ath

116 Exertional heat illness (EHI) and malignant hyperthermia

117 The development of exertional heat illness (EHI) is a health, welfare and p

118 Exposure to exertional heat stroke (EHS) has been linked to increase

119 Exposure to exertional heat stroke (EHS) has been linked to increase

120 Exposure to exertional heat stroke (EHS) is associated with a higher

121 Exposure to exertional heat stroke (EHS) is associated with increase

122 Exertional heatstroke sporadically affects predominantly

123 ts with ESRD, raising the concern for severe exertional hyperkalemia.

124 for hypoglycemia; techniques for cooling of exertional hyperthermia and heatstroke; recognition of a

125 e) or ILD (low-quality evidence) with severe exertional hypoxemia, 4) a conditional recommendation fo

126 mes on spirometry, severely impaired Dl(CO), exertional hypoxemia, frequent pulmonary hypertension, a

127 SCD events were exertional in 50% of cases.

128 0.34, p = 0.04) and change with treatment in exertional increase in the ratio of peak early diastolic

129 on, 2 predominant mechanisms responsible for exertional increases in heart rate, in patients with HFp

130 siveness, an important mechanism involved in exertional increases in HR, in HFpEF and control subject

131 hemoglobin AS (HbAS) and who were subject to exertional-injury precautions.

132 n several components may interact to promote exertional intolerance in HFpEF.

133 thesis of a peripheral origin of symptoms of exertional intolerance in this syndrome is confirmed as

134 Exertional intolerance is a limiting and often crippling

135 Potential mechanisms for exertional intolerance other than deconditioning include

136 METHODS AND Among 65 patients with exertional intolerance undergoing upright invasive exerc

137 Exercise capacity and symptoms of exertional intolerance were correlated with abnormalitie

138 lpitations, dyspnea, chest pain, presyncope, exertional intolerance, and fatigue, although approximat

139 was associated with worse functional class, exertional intolerance, and increased mortality in PAH,

140 e exercise capacity and identify patterns of exertional intolerance.

141 iopulmonary exercise testing for unexplained exertional intolerance.

142 eline investigations, there were no signs of exertional ischemia, wall motion abnormality, or cardiac

143 oup without exertional leg pain/inactive (no exertional leg pain in individual who walks </=6 blocks

144 The differential diagnosis of exertional leg pain includes stress fractures, stress re

145 Although exertional leg pain is a hallmark of peripheral arterial

146 atypical exertional leg pain/carry on group (exertional leg pain other than IC associated with walkin

147 the atypical exertional leg pain/stop group (exertional leg pain other than IC that causes one to sto

148 No category of exertional leg pain was sufficiently sensitive or specif

149 ptomatic (participants who never experienced exertional leg pain, even during the 6-minute walk; n=72

150 Among participants without exertional leg pain, lower ABI levels were associated wi

151 xty-three percent of PAD participants had no exertional leg pain.

152 isk variables were independent correlates of exertional leg pain.

153 arization were all significant correlates of exertional leg pain.

154 an Diego Claudication Questionnaire assessed exertional leg pain.

155 compared with IC, participants with atypical exertional leg pain/carry on achieved a greater distance

156 The atypical exertional leg pain/carry on group (exertional leg pain

157 The group without exertional leg pain/inactive (no exertional leg pain in

158 through leg pain [n = 41]) and the atypical exertional leg pain/stop group (exertional leg pain othe

159 an ABI value less than 0.90 either report no exertional leg symptoms (ie, asymptomatic) or report leg

160 s, 30% to 60% of patients with PAD report no exertional leg symptoms and approximately 45% to 50% rep

161 Persons with PAD who never experience exertional leg symptoms have poorer functional performan

162 ng in those who are asymptomatic or who have exertional leg symptoms other than claudication.

163 symptoms and approximately 45% to 50% report exertional leg symptoms that are not consistent with cla

164 linical syndrome characterized by dyspnea or exertional limitation due to impairment of ventricular f

165 ribe 28 patients with unexplained dyspnea or exertional limitation secondary to biopsy-proven mitocho

166 therapeutic target for aged individuals with exertional limitations.

167 es and patellofemoral pain syndrome; chronic exertional lower-leg compartment syndrome, ankle sprains

168 We sought to confirm ACE genotype-associated exertional LV growth and to clarify the role of the AT(1

169 taste or smell (9.8% (7.7% to 11.8%)), post-exertional malaise (9.4% (6.1% to 12.7%)), fatigue (5.4%

170 are associated with an elevated risk of post-exertional malaise (PEM), an acute exacerbation of sympt

171 Post-exertional malaise (PEM), defined as the exacerbation of

172 th the development of PCS with fatigue, post-exertional malaise (PEM), orthostatic dysregulation, aut

173 ptoms are described, including fatigue, post-exertional malaise and cognitive impairment.

174 fluid indicated distinct mechanisms for post-exertional malaise in CFS and START and STOPP phenotypes

175 Post-exertional malaise suggests exercise alters central nerv

176 frequently report unremitting fatigue, post-exertional malaise, and a variety of cognitive and auton

177 new onset of symptoms such as fatigue, post-exertional malaise, and cognitive dysfunction that last

178 tisystemic condition marked by fatigue, post-exertional malaise, and other symptoms resembling myalgi

179 e veterans with GWI exhibit fatigue and post-exertional malaise, we employed an intermittent voluntar

180 ompanies erratic heart rates and severe post-exertional malaise.

181 mplain about chronic fatigue and severe post-exertional malaise.

182 order manifesting as severe fatigue and post-exertional malaise.

183 IONALE: An increased ventilatory response to exertional metabolic demand (high [Formula: see text]e/[

184 ycogen storage disease in humans that causes exertional myopathy and hemolysis.

185 somal recessive disorder characterized by an exertional myopathy and hemolytic syndrome.

186 d as an incidental finding (n=80, 49%), with exertional (n=31, 21%) and nonexertional (n=32, 20%) sym

187 The reduced exertional obstruction may account for the better functi

188 Because symptoms of HFpEF are typically exertional, optimization of diastolic filling time by co

189 issections are preceded by a specific severe exertional or emotional event.

190 ve, prompting an individualized approach and exertional oxygen testing if a patient is mobile and rep

191 than unstable angina patients with crescendo exertional pain (n = 18): 71.1% versus 52.4% (p < 0.001)

192 nse in this group was associated with higher exertional PcO2.

193 tients with congenital heart disease impacts exertional performance and pulmonary artery growth.

194 to placebo had a respective 40% increase in exertional (play) (951 versus 569 [491, 647]; p < 0.0001

195 nant of aerobic capacity among patients with exertional pulmonary venous hypertension (ePVH).

196 the risk of kidney failure in patients with exertional rhabdomyolysis (ERM) has been suggested.

197 with a significantly higher adjusted risk of exertional rhabdomyolysis (hazard ratio, 1.54; 95% CI, 1

198 -hazards models to test whether the risks of exertional rhabdomyolysis and death varied according to

199 that sickle cell trait elevates the risks of exertional rhabdomyolysis and death.

200 omes, controlling for known risk factors for exertional rhabdomyolysis, in a large population of acti

201 sociated with a significantly higher risk of exertional rhabdomyolysis.

202 In conclusion, resting and exertional RV functions are preserved in response to acu

203 objective of this study was to characterize exertional RV performance during acute hypoxia.

204 academic year; P = 0.007) and survival from exertional SCA (range 38%-72% per academic year; P = 0.0

205 Among exertional SCA events, survival was higher among athlete

206 Exertional SCD was more common among those with coronary

207 mated survival proportion ratios by race and exertional status.

208 es and to explore outcomes based on race and exertional status.

209 ders by stress, the effect of psychologic or exertional stress on human skin has not been well studie

210 s (10, 55.6%), nonexertional (4, 22.2%), and exertional symptoms (4, 22.2%), were enrolled at a media

211 iastolic function (average e' and E/e'), and exertional symptoms (NYHA II-IV and peak oxygen consumpt

212 All 4 patients with exertional symptoms and 3/10 (30%) with no or nonexertio

213 ow and independent determinants of disabling exertional symptoms and cardiovascular mortality.

214 However, exertional symptoms frequently underestimate the severit

215 ese indices and LV diastolic dysfunction and exertional symptoms has not been studied.

216 vestigate the relationship over time between exertional symptoms in heart failure and functional capa

217 Most clinicians rely on exertional symptoms rather than on exercise testing to a

218 Exertional symptoms reported by patients with heart fail

219 amural length, slit-like/hypoplastic ostium, exertional symptoms, or evidence of ischemia.

220 its ability to respond to stress; leading to exertional symptoms.

221 testing if a patient is mobile and reporting exertional symptoms.

222 t correlation with LV diastolic function and exertional symptoms.

223 tricular tachycardia [6], near-drowning [2], exertional syncope [1], symptoms on therapy [2], LQT3 [1

224 rocedure, exercise capacity was improved and exertional syncope abolished.

225 ded cardiac ryanodine receptor in cases with exertional syncope and normal corrected QT interval (QTc

226 disease is known or suspected or those with exertional syncope are at higher risk for adverse outcom

227 Angina, exertional syncope, and heart failure are key symptoms i

228 f life ranged from subclinical to occasional exertional syncope.

229 These were two of only six patients who had exertional syncope.

230 iagnosis, black race, intramural course, and exertional syncope.

231 avorable effects of mavacamten on submaximal exertional tolerance provide further insights into the b

232 on of patients with PASC complaining of poor exertional tolerance, tachycardia with minimal activity

233 Reduction in BP was related to improved exertional total arterial compliance (ETD, 0.06 mL/mm Hg

234 The chronic or exertional type most commonly involves the lower extremi

235 etes with symptoms of syncope, especially if exertional, warrant a complete evaluation.

236 xposure to extreme environmental heat and as exertional when it develops during strenuous exercise.