ライフサイエンスコーパス: exogenous

1 nvolves genetic and environmental factors or exogenous.

2 nd protein levels in darkness in response to exogenous ABA treatment by binding directly to the G-box

3 1R in the cerebellum, in which endogenous or exogenous activation of CB1Rs modifies afferent synaptic

4 The exogenous addition of 14-3-3 to beta-adrenergic-stimulat

5 were incapable of activating FX without the exogenous addition of FX and had a marked increase in FX

6 Replication of both strains is sensitive to exogenous addition of IFNs, suggesting the potential of

7 n of KDM6B with GSK-J4 inhibitor and through exogenous addition of IL-11 that the host responses to t

8 surfactant-deficient phenotype is rescued by exogenous addition of surfactant replacement formulation

9 nd as such, several approaches making use of exogenous additives, or "spike-ins," have recently been

10 ine, the biomaterial is also able to deliver exogenous adenosine to the site of injury, offering a ve

11 ed to peanut flour by inhalation without any exogenous adjuvants.

12 ggesting a potential therapy for hepatic IR, exogenous administration of butyrate or propionate prote

13 People with type 1 diabetes (T1D) require exogenous administration of insulin, which stimulates th

14 Exogenous administration of miR-127, which is functional

15 PGE(2) production in the lung; accordingly, exogenous administration of PGE(2) reduced inflammation

16 Exogenous administration of RA during late gestation par

17 nt manner in vitro In a murine model of CDI, exogenous administration of ursodiol resulted in signifi

18 Exogenous administration of VEGF-C via an adenoassociate

19 er assess the therapeutic potential of their exogenous administration, we report on the development o

20 Inducing contractions of expanded repeats by exogenous agents is not yet possible.

21 ant receptor is controlled by endogenous and exogenous agents that elicit or exacerbate pain and itch

22 ion of immune/inflammatory responses against exogenous allergens, microbial substances, and pollutant

23 ings on acute hippocampal slices showed that exogenous Amh protein addition increased synaptic transm

24 ular DNA is constantly chemically altered by exogenous and endogenous agents.

25 Exogenous and endogenous chemicals can react with DNA to

26 iopathies," in which cholangiocytes react to exogenous and endogenous insults, leading to disease ini

27 PYSNO exhibited a rapid response to both exogenous and endogenous NO.

28 induced by eCO(2) alter the balance between exogenous and endogenous sources of immunity remains unk

29 s suggest that shifts in the balance between exogenous and endogenous sources of immunity to parasite

30 bonylation level that differs in response to exogenous and endogenous stress in healthy and cancer ce

31 cells to protect their genome from numerous exogenous and endogenous threats.

32 he interplay between the genetic background, exogenous, and endogenous factors within human health.

33 Rationale: Exogenous angiotensin II increases mean arterial pressur

34 Exogenous angiotensin II reduced catecholamine vasopress

35 the local inflammation without the need for exogenous anti-inflammatory agents.

36 s, in situ immunization without the need for exogenous antigens, inhibition of the progression of lun

37 in human subjects, for stable expression of exogenous antigens.

38 in our understanding of both endogenous and exogenous antioxidants in tumorigenic processes.

39 However, exogenous antithrombin itself may increase the risk of b

40 Exogenous application of ACC led to BS symptoms, while e

41 Exogenous application of auxin can dramatically enhance

42 dwarfed plants that could be rescued by the exogenous application of bioactive GA(4), confirming tha

43 Furthermore, exogenous application of indole-3-acetic acid (IAA) or a

44 of endogenous lipid biosynthetic pathways or exogenous application of lipid.

45 Exogenous application of phosphorylated PHS (PHS-P) indu

46 Exogenous application of PHS-P rescues loss-of-PTI in ME

47 However, PARs are also activated by exogenous application of synthetic peptides derived from

48 iption factor 4 (ATF4) and overexpression of exogenous ATF4 cDNA indicated that ATF4 up-regulates LAM

49 e are two forms of covert spatial attention: exogenous attention is automatic, stimulus-driven, and t

50 her early visual areas mediate the effect of exogenous attention on performance.

51 ly visual areas and the modulatory effect of exogenous attention on performance.

52 ciation approach that allowed us to evaluate exogenous attention shifts to locations within and beyon

53 When the distractor was stimulated, exogenous attention yielded response gain-performance be

54 Notably, it has been postulated that only exogenous attention, but not endogenous attention, would

55 ectively), pre- or post-cueing endogenous or exogenous attention, while participants performed the sa

56 atdro1 lateral roots were able to respond to exogenous auxin and AtDRO1 gene expression levels in roo

57 Thus, exogenous auxin induces transverse microtubule patternin

58 ntration; feeding the transgenic leaves with exogenous auxin partially restores leaf width.

59 ntal supplies as the inverse of their use as exogenous baits.

60 erpes zoster predicted from modelling of the exogenous boosting hypothesis was not observed.

61 Without the exogenous boosting hypothesis, HZ incidence decreased th

62 The exogenous boosting hypothesis, which postulates that ree

63 ambient CO(2)) on exogenous Bt toxins and transgene expression in promoter

64 phosphatase whose activity is influenced by exogenous butyrate to control the level of endogenous ph

65 In this study, we hypothesized that exogenous calcium influences specific polyphenolic compo

66 Upon exogenous calcium treatment, Rcr1 ubiquitinates and down

67 Exogenous cAMP partially restored the mutant appressoriu

68 s-related compounds, makes understanding how exogenous cannabinoids affect brain development an impor

69 ications for recreational and medical use of exogenous cannabinoids by pregnant and breastfeeding wom

70 slower evidence accumulation, demonstrating exogenous capture of spatial attention.

71 helial cancerization field in the absence of exogenous carcinogens or promoters requires a two-field

72 Administration of exogenous CD147 enhanced MMP-2 expression in HGFs, where

73 In contrast, exogenous cell permeable itaconate, 4-octyl itaconate (O

74 lymphoblastic leukemia (T-ALL) cells require exogenous cells or signals to survive in culture.

75 from the SF of patients were incubated with exogenous CG and lubricin degradation was monitored usin

76 MS-based methods can detect the low-abundant exogenous chemicals in human matrixes.

77 redicting potential endocrine disruption via exogenous chemicals requires that aromatase inhibition b

78 Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with hormone action,

79 Furthermore, infection was rescued by adding exogenous cholesterol.

80 This study examined the effects of exogenous citrulline (control, 1 and 2 mM) and water ava

81 Incubation of Taz(KD) mitochondria with exogenous CoA partially rescued pyruvate and palmitoylca

82 Pre-harvest application of exogenous compounds has been employed in many crops, as

83 asculature at microscale resolutions without exogenous contrast agents.

84 ascular endothelium does not just respond to exogenous cytokines, but exerts active "angiocrine" gate

85 ficient wheat regeneration in the absence of exogenous cytokinins, which facilitates selection of tra

86 We hypothesized that effective exogenous delivery of antioxidant enzymes - superoxide d

87 To explore aflatoxin control by exogenous delivery of double-strand RNA (dsRNA) it is ne

88 Here, we overcome this difficulty by exogenous delivery of human ACE2 with a replication-defi

89 Silencing of exogenous DNA can make transgene expression very ineffic

90 rtantly, while the presence of endogenous or exogenous DNA damage has the potential to impact PGCs, t

91 Inducing oxidative stress or exogenous DNA damage leads to an earlier onset of polypl

92 increased levels in E. coli cells exposed to exogenous DNA damaging agents, including many commonly u

93 Competence allows bacteria to internalize exogenous DNA fragments for the acquisition of new pheno

94 ntegration of up to more than 3 kilobases of exogenous DNA in the genome of hMSCs derived from the bo

95 mutation rates, but the precise insertion of exogenous DNA or gene knock-in via the homology-directed

96 icism, including mitochondrial heteroplasmy, exogenous DNA sources such as vectors, and epigenetic ch

97 extending from the cell surface, binding to exogenous DNA, and retracting to thread this DNA through

98 ncNMR silencing decreases dNTP levels, while exogenous dNTPs rescues the proliferation defect induced

99 teome over 2 to 3 days in the absence of any exogenous drivers such as daily light or temperature cyc

100 ures of the channel pore can be modulated by exogenous drugs that bind outside the pore.

101 c acid, and is involved in the metabolism of exogenous drugs.

102 nvestigation in a mouse model overexpressing exogenous DUX4 confirmed the therapeutic effects of berb

103 the retina and requires the insertion of an exogenous dye with potential adverse side effects.

104 egatively impacted by surgical manipulation, exogenous dyes, transgenic manipulation and phototoxicit

105 Finally, exogenous E2 administration fully rescued the compromise

106 ecies because it exhibits self-resistance to exogenous echinocandins.

107 N(2) O to N(2) +H(2) O in the presence of an exogenous electron donor (CoCp(2) ).

108 AM complex accelerates folding without using exogenous energy (for example, ATP)(9), we trapped foldi

109 ation of target genes at high levels without exogenous enhancer elements.

110 nces vary across sociopolitical contexts and exogenous environments.

111 incorporated into RNA in cells expressing an exogenous enzyme.

112 This process obviates the need for exogenous enzymes and redox mediator supplements.

113 cial enzyme (on average 0.4%/min), while all exogenous enzymes were able to hydrolyse the pentapeptid

114 Exogenous EphA7 extracellular domain will rescue the nul

115 verexpression studies and the application of exogenous epoxides.

116 ripened completely, even when supplied with exogenous ET.

117 By exogenous expression in HeLa cells, we tested the functi

118 ity and infectivity was also restored by the exogenous expression of a cloned A* gene.IMPORTANCE Doub

119 Exogenous expression of miR-181c inhibited ATM expressio

120 lated in uninfected endothelial cells by the exogenous expression of ORFK12 and by the treatment of c

121 Knockdown or exogenous expression of TBL1XR1 was combined with in vit

122 gnificantly, inhibition of GSK-3 activity or exogenous expression of the GSK-3 substrate collapsin re

123 bleeding events was 0, and the median use of exogenous factor VIII was reduced from 138.5 infusions t

124 igration timing of long-distance migrants to exogenous factors has been consistently underestimated d

125 Our findings suggest that exogenous factors, such as procedural differences betwee

126 in Fe homeostasis that could be reverted by exogenous Fe supply.

127 een endogenous FeLV (enFeLV) copy number and exogenous FeLV (exFeLV) infection outcomes in domestic c

128 nFeLV-LTR elements negatively correlate with exogenous FeLV replication.

129 t growth factor (FGF) signaling pathway, and exogenous FGF rescues the myogenic differentiation defec

130 its electrical response with the addition of exogenous flavin, and quantitative analysis of this demo

131 lar distribution of PI, including localizing exogenous fluorescent PI, as well as detecting lipid con

132 to trace nutrients from endogenous stores or exogenous food intake into offspring.

133 hology results from patterned endogenous and exogenous forces and their interplay with tissue mechani

134 capacity of the endogenous virus against the exogenous form, either via direct interference or indire

135 rom both sites were divided and treated with exogenous FSH.

136 Furthermore, when exogenous FXIII was topically applied into the wound poc

137 In mice, exogenous G-3-P stimulated bone and bone marrow FGF23 pr

138 We show that bmr12 is more sensitive to exogenous GA application and present evidence for the ro

139 tracing, a process that can be suppressed by exogenous gastrin treatment.

140 mmunity comes largely from administration of exogenous GCs to treat immune or inflammatory disorders.

141 ection, a common form of naturally occurring exogenous gene translation.

142 We hypothesized similar effects for CUB of exogenous genes on host translation, and tested it in th

143 at they had packaged a broad distribution of exogenous genomic material.

144 ll wall, phenotypes that could be rescued by exogenous GlcNAc, the product of the Gna1 enzyme.

145 Whereas exogenous glucose administration or restoration of hepat

146 ediate, alpha-ketoglutarate, suggesting that exogenous glutamine is an essential carbon source for th

147 Treating amino-acid-deprived cells with exogenous glutamine or glutaminase inhibitors restores t

148 We found that limiting exogenous glutamine protects actively dividing amastigot

149 r injury and immune hyperactivation, whereas exogenous gp96 aggravated the symptoms of hepatic injury

150 uding metabolism, to couple the signals from exogenous growth factors, cytokines or hormones to adapt

151 on and motility, and decreases dependence on exogenous growth factors.

152 FR signaling and reduce a cell's reliance on exogenous growth factors.

153 of cell growth, survival and metabolism from exogenous growth stimuli.

154 t, excess protein, cholesterol, lactose, and exogenous hormones; and that vulnerable populations are

155 ory growth experiments, supplementation with exogenous hydrogen peroxide enhanced E. coli growth thro

156 In higher plants, molecular responses to exogenous hypoxia are driven by group VII ethylene respo

157 m of endogenous (i.e., salivary protein) and exogenous (i.e., dietary carbohydrates) substrates.

158 We found that exogenous IAP induced autophagy in intestinal epithelial

159 receptor (Ifnar1(-/-)) and administration of exogenous IFN-beta were used to study the functional rol

160 sistent with this observation, we found that exogenous IFN-gamma suppressed macrophage phagocytosis o

161 ed inflammatory cytokines in the presence of exogenous IL-10.

162 5-deficient BMMs is substantially rescued by exogenous IL-1beta or IL-18.

163 viral infection, and this can be overcome by exogenous IL-2 administration.

164 We show that treatment with exogenous IL-33 results in a generalized downregulation

165 Importantly, the injection of exogenous IL-35 stimulated the elevation in the counts o

166 Restoration of IL-6 by administration of exogenous IL-6 ameliorated AILI in HIF-2alpha(mye/-) mic

167 ther, these results suggest that the loss of exogenous immunity from foliage under eCO(2) results in

168 s (cardenolides), provide a potent source of exogenous immunity.

169 the adaptive immune response, thus enabling exogenous immunosuppressive therapy to be significantly

170 r cells from the host's immune system and/or exogenous immunotherapies.

171 e internationals in the United States and an exogenous influx of foreign capital associated with thei

172 rely on engineering proteases to respond to exogenous inputs such as light or chemicals.

173 ic (PKPD) model providing the ability to fit exogenous inputs to specific bioavailability and affinit

174 T1D) include donor pancreas transplantation, exogenous insulin administration and immunosuppressive t

175 s daily injections or continuous infusion of exogenous insulin aimed at regulating blood glucose leve

176 on now sustainable only by administration of exogenous insulin.

177 ory factor 7 (IRF7) induction in response to exogenous interferon (IFN).

178 We show that detection of an exogenous internal control using dHRM analysis reduces t

179 Since the defect is abrogated by exogenous intrarenal cGMP, the renal cGMP pathway may re

180 How do endogenous (voluntary) and exogenous (involuntary) attention modulate activity in v

181 gaze paralysis show conventional benefits of exogenous (involuntary) attention, confirming that cover

182 d post ferumoxytol injection to discriminate exogenous iron susceptibility from other endogenous sour

183 e but lacks suitable methods for quantifying exogenous irons such as superparamagnetic iron oxide (SP

184 inistration of a calorie-matched glucose and exogenous ketone ester (d-beta-hydroxybutyrate) bolus.

185 mited data demonstrate beneficial effects of exogenous ketone therapy in studies of animal models and

186 We rescued this effect by the addition of exogenous KIF11.

187 ts reveal bats to be important reservoirs of exogenous KoRV-related gammaretroviruses.

188 We find that exogenous L-arginine is essential for ISCs proliferation

189 ve allylic substitution in the absence of an exogenous ligand.

190 per proteins which could be tuned blue using exogenous ligands, but the question of how one can creat

191 rons of the trigonal prism in the binding of exogenous ligands.

192 rescence quenching confirmed the delivery of exogenous lipids to the cell outer leaflet.

193 y to prevent inflammasome-mediated diseases, exogenous LTB(4) can be used as an adjuvant to boost inf

194 Exogenous Mel inhibits neurotransmitter release and prom

195 tivation, and inflammation, all inhibited by exogenous melatonin.

196 rce of MR1 molecules for the presentation of exogenous metabolite antigens to MAIT cells.

197 In vitro, exogenous miR-370-3p inhibits HCN4 mRNA and causes downr

198 Here, we show that exogenous Mn can restore A. baumannii viability in the p

199 tential deleterious, pro-fibrotic effects of exogenous MSCs once intravitreally injected into clinica

200 Uncovering factors that stabilize exogenous mtDNA integration will improve our understandi

201 s following uridine-free selection, although exogenous mtDNA is lost from metabolically impaired, mtD

202 Our results suggest that exogenous mtDNA retention in metabolically impaired rho+

203 idylethanolamine (PE) biosynthesis; however, exogenous NBD-phosphatidylcholine, Bodipy-PE, and TopFlu

204 physiological conditions and when exposed to exogenous neuroinflammatory mediators and hence may have

205 Exogenous NO, nitrite and nitrosothiols react with place

206 Exogenous noise changed the actual values of the CA para

207 The influence of exogenous noise on CA parameters needs further investiga

208 The influence of exogenous noise was investigated by adding three levels

209 bably increase the risk of acquisition of an exogenous nonprimary CMV infection and fetal transmissio

210 Conditioned-medium from NF2-null ACs or exogenous NRG1 stimulated ERBB3, EPHA2, and mTORC1/2 sig

211 typic AST that measures DNA accessibility to exogenous nucleases after exposure to beta-lactams (term

212 and RNA as part of the adaptive response to exogenous nucleic acid-alkylating agents.

213 explore the allocation of endogenous versus exogenous nutrients across the capital versus income spe

214 Although previous studies show that exogenous nutrients regulate the stem cell function, lit

215 Ru complex undergoes the coordination of an exogenous OH(-) group from the solvent that leads to an

216 Inflammation induced by exogenous or endogenous agents can be detrimental and, i

217 s, we revealed associations of signatures to exogenous or endogenous exposures, as well as to defecti

218 polymers and nanoparticles, which respond to exogenous or endogenous stimuli in the tumor microenviro

219 generated linguistic content over and above exogenous or stimulus-driven timing and rhythm informati

220 have been studied only in animal models with exogenous or transgenic labeling.

221 Moreover, we show in vitro that exogenous osteopontin stimulates the survival of murine

222 Exogenous overexpression and pharmacologic induction of

223 f the cytosol and mitochondrion to cope with exogenous oxidative stresses, indicating a direct link b

224 The mechanism and location of action of exogenous OXT are unknown.

225 phorylation, which is rescued by addition of exogenous palmitate.

226 Expression of exogenous PAM in Pam (Myh6-cKO/cKO) atrial myocytes prod

227 Exogenous pathogen-derived molecules (eg, lipopolysaccha

228 nd Treg cells showed attenuated responses to exogenous PGD2.

229 Exogenous PGE(2) attenuated bone marrow-derived cultured

230 is a key component of photodynamic therapy, exogenous photothermal contrast agents are not required

231 Exogenous Pip partially restored SAR in jmj14 plants, su

232 We also describe approaches for introducing exogenous plasmid constructs and for sparse cell labelin

233 polyamine depletion could not be rescued by exogenous polyamines, thereby obviating the need for a P

234 Specifically, exogenous polyunsaturated fatty acids are rapidly incorp

235 oration of central PPA levels by delivery of exogenous PPA is a recent strategy to reactivate CoA bio

236 techniques require either the use of special exogenous probes, high illumination doses or multiple im

237 al practice that needs efficient delivery of exogenous probes.

238 piratory syndrome (MERS)-like bat CoVs using exogenous protease treatment.

239 ubiquitination does not promote any specific exogenous protein:protein interactions, but instead stab

240 Current metabolic labeling methods rely on exogenous pyrimidine analogs that are only incorporated

241 Second, a single expense descriptor is an exogenous quantity that does not evolve from income-expe

242 suggests that oak masting is synchronised by exogenous rather than endogenous factors.

243 Ligation of rC0C7 (exogenous [recombinant] N'-terminal domains C0 to C7 of

244 in AKR but could be moderately induced with exogenous, recombinant IL33.

245 mydomonas reinhardtii in interaction with an exogenous redox mediator (2,6-dichlorobenzoquinone; DCBQ

246 Using SCE-FISH, we find that endogenous and exogenous replication stress generated unrepaired breaks

247 ion can play a beneficial role in mitigating exogenous retroviral infections.

248 , to date they have not been shown to harbor exogenous retroviruses.

249 of these diet conditions, administration of exogenous rGDF11 reduced body weight by 3-17% and signif

250 ely, our results show that administration of exogenous rGDF11, but not rGDF8, can reduce diet-induced

251 ow that sRNA sequencing is useful to compare exogenous RNAi delivery methods on peanut plants, and to

252 The oxidase-like activity and exogenous ROS generation have been further exploited in

253 In support of this, exogenous ROS increased glucose consumption while inhibi

254 ets was indistinguishable in the presence of exogenous ROS/H(2)O(2) Together, these data provide a mo

255 arious inflammatory diseases, we examined if exogenous RvD1 could modulate the pathogenesis of Chagas

256 Exogenous RvD1 enhances perfusion recovery during ischem

257 Interestingly, supplement of exogenous secreted Klotho prevented heart failure, hyper

258 Supplement of exogenous secreted Klotho represents a promising therape

259 may be especially useful for integration of exogenous sequences into valuable therapeutic target cel

260 elease serine (Ser) to support the growth of exogenous Ser (exSer)-dependent PDAC cells during Ser/Gl

261 ose growth and self-renewal require abundant exogenous serine.

262 We model the change in mobility as an exogenous shock similar to a natural disaster.

263 It also enables metabolic incorporation of exogenous sialic acids, leading to autoantibodies agains

264 controlling responses to both endogenous and exogenous signals.

265 We investigated the effect of an exogenous source of carbon (glycerol), energy (ATP), and

266 Animals rely on a balance of endogenous and exogenous sources of immunity to mitigate parasite attac

267 k contains live bacteria from endogenous and exogenous sources, but it remains unclear whether these

268 ve regulators of nuclear RNAi triggered from exogenous sources.

269 tions, elicited by electrical stimulation or exogenous SP, were recorded in the presence or absence o

270 ted in human cells from asthma subjects when exogenous SP-A is added during IL-13 challenge.

271 hoblastoid cells are capable of transporting exogenous spermine and its analogs into the cell and, in

272 ering rotenone/DFMO-induced MitoROS, whereas exogenous spermine quenched rotenone-induced MitoROS via

273 tions and treatments, which does not rely on exogenous spike-in chromatin or peak detection to reveal

274 escence occurs in response to endogenous and exogenous stresses, including telomere dysfunction, onco

275 ructive, efficient, and reliable analysis of exogenous substances deposited within fingerprints.

276 In the presence of 0.25 M exogenous sucrose, increased catabolism was observed wit

277 sibility of detecting undeclared addition of exogenous sugar products in foods and beverages suscepti

278 The three drivers that best predict exogenous sugar use by ants all point to factors constra

279 diverse range of antibacterial pathways and exogenous surfactant can improve pulmonary drug distribu

280 ely, mixing AMPs with commercially available exogenous surfactants has been shown to negatively impac

281 One proposed strategy is the use of exogenous surfactants to deliver antimicrobial peptides

282 ed a molecular replacement strategy in which exogenous SV2A was expressed in mouse neuronal cultures

283 In young adult hearts, exogenous T3 increases cardiomyocyte numbers after DUSP5

284 Here, we show that exogenous T3 increases the cardiomyocyte endowment of P8

285 anthocyanin profile, and the effect of five exogenous tannin formulations differing in origin and ch

286 In winemaking, exogenous tannins are added before maceration to improve

287 The administration of exogenous target-specific triggers offers the potential

288 e recovered from mRNA, and SRTs deposited by exogenous, TF-transposase fusions can be used to map TFB

289 In vitro assays revealed exogenous TGF-beta1 increased OASIS expression coinciden

290 on upon Treg restimulation in the absence of exogenous TGF-beta1.

291 However, in the presence of exogenous TGFbeta2, VehMs and GIMs activate Smad and non

292 We have previously shown that exogenous thyroid hormone (T3) stimulates cardiomyocyte

293 Counteracting the tPA reduction with exogenous tPA or with pharmacological inhibition or gene

294 hether permeability to individually injected exogenous tracers-as is standard in BBB studies-fully re

295 vation of gene expression without the use of exogenous transcription regulatory proteins are lacking.

296 tivating machinery, eliminating the need for exogenous transcriptional activators.

297 Here, we show that, in the absence of exogenous transforming growth factor-beta2 (TGFbeta2), c

298 n of Vero and human cells in the presence of exogenous trypsin.

299 ting that reinfection through exposure to an exogenous virus is responsible for some cases of nonprim

300 mIMCD3 cells produces hyperresponsiveness to exogenous Wnt ligands, which is inhibited by siRNA-media