ライフサイエンスコーパス: expand

1 nd long-acting formulations as PrEP roll-out expands.

2 arding long-term postoperative LMWH has been expanded.

3 ghbors during a period when higher education expanded.

4 gradient in fiber organizations is formed by expanding 2D nanofiber membranes composed of multiple re

5 In addition, treatment expanded a CXCR3+PD1-/low CD8 T-cell subset with the abi

6 on migratory riverine populations, we first expanded a spatial stream network model to predict mean

7 Virtual care is important for expanding access to health services, but strategies are

8 ingle-institution ancillary trial within the expanded-access program (NCT02475382) for nivolumab.

9 red within the Early Classic phase when Maya expanded across Central America.

10 ng blood factors may be a useful strategy to expand adult beta cell mass.

11 (+) TRD rearrangements did not significantly expand after birth.

12 hough ecological release predicts species to expand after extinction events, survivors of intervals w

13 Expanded air transport quality assurance protocols, incl

14 Hyp mandibles demonstrated expanded alveolar bone with accumulation of osteoid, and

15 ts with a new Lpar1 conditional mouse mutant expand an understanding of LPA(1) signaling in the PSNL

16 tional medicines, including their ability to expand and contract in proportion to need and to mediate

17 Follow-up analyses revealed that clones may expand and decline, generally showing only a subtle incr

18 IL-10, transforming growth factor-beta) that expand and differentiate both pathogenic and regulatory

19 erves to reinforce our drive towards further expanding and growing the maturity of nanomedicine for g

20 as a genome engineering tool and may inspire expanded applications that exploit sensitivity to DNA su

21 documented antimicrobial use in the rapidly expanding aquaculture industry, which may contribute to

22 ghlights the recent advances in this rapidly expanding area, which experienced an unprecedented momen

23 ronchoscopy is now able to provide a new and expanding armamentarium of diagnostic and therapeutic to

24 survivors of intervals with net species loss expanded as rarely as species in other intervals.

25 Adoptive T cell therapy (ACT) using ex vivo-expanded autologous tumor-infiltrating lymphocytes (TILs

26 two distinct fates: one set of biofilm cells expanded ballistically outward, while the other became t

27 duced their variance, whereas high-dose AMPH expanded both.

28 and nonexpander states as those who had not expanded by December 31, 2018.

29 transmission within reservoir areas, further expanded by periodic importations to areas of high immun

30 ited neurodegenerative disorder caused by an expanded CAG repeat in the HTT gene.

31 ck-fluid reactions) before demonstrating the expanded capabilities offered by the underlying FE found

32 n altered morphological state, by exhibiting expanded cell body size and retracted processes.

33 Histone variants expand chromatin functions in eukaryote genomes.

34 In addition, expanding clinical applications of SPECT/CT in other are

35 ived cardiomyocytes (hiPSC-CMs) in vitro can expand CMs modestly (<5-fold).

36 , suggesting sequence patterns that favor an expanded conformational ensemble are under selection for

37 This protocol thus expands CRISPR-based gene editing approaches beyond mode

38 Additional interventions, including expanded critical care capacity and an effective therape

39 s routinely removed during surgery; (ii) The expanded CTG mutation is one of the most prevalent disea

40 into plant polyploidization strategies that expand current concepts on the evolution of flowering pl

41 Our findings substantially expand current knowledge on genes that regulate LTL and

42 With this FTIR method we expand current options to investigate the interfacial be

43 est for coronavirus disease 2019 would allow expanding current screening capacities, thereby enabling

44 cells susceptible to reovirus infection and expands current understanding of the receptors on microg

45 175 (22.8%) patients failed CS by strict and expanded definitions, respectively.

46 s been demonstrated as a promising method to expand DEL reactivity using standard organic synthesis p

47 Expanding delivery of primary healthcare to urban poor p

48 e not suitable for biostable, rigid and self-expanding devices.

49 n disease-modifying treatment and who had an Expanded Disability Status Scale (EDSS) score of 4.0-6.5

50 e of relapses, new white matter lesions, and Expanded Disability Status Scale [EDSS] change) were ide

51 thinning was the primary determinant of the Expanded Disability Status Scale, white matter lesion fr

52 ry outcome was disability, measured with the Expanded Disability Status Score (EDSS; an ordinal scale

53 We also discuss the expanding diversity and functions associated with histon

54 r study were to investigate interventions to expand donor options and to prevent ART interruptions fo

55 EVE first emerged in streptophyte algae, but expanded dramatically among vessel-containing angiosperm

56 storical drylands outpaces the higher GPP of expanded drylands.

57 loss, increased geopolitical attention, and expanding economic activity resulting in a dramatic incr

58 ion of Foxp3(+) T cells, whereas high levels expanded effector T cells and caused severe autoimmunity

59 nhancing T cell cycling and differentiation, expanding effector-memory T cells and inducing robust vi

60 Dramatic methodological changes, designed to expand eligibility for allo-HSCT to older patients and/o

61 inclusion of injectable medications into an expanded ESKD payment bundle prompted concerns that dial

62 fication of non-coding somatic variation and expanded estimation of background mutation rates, yet fe

63 The cells were expanded ex vivo and administered in a single infusion a

64 f intracranial tumours, and its use has been expanded for the treatment of intraocular malignancies.

65 eding by tropical herbivores is predicted to expand from the northern Caribbean to extratropical reef

66 role of angiotensin converting enzyme 2 has expanded from regulating the renin angiotensin system to

67 c evolution of a nearly collisionless plasma expanding from a central thermal source.

68 es an example of a weakly collisional plasma expanding from a thermal source in the presence of spati

69 We demonstrated that only a fraction of expanded gamma9delta2T cells was active against cancer c

70 el accurately describes the slowly-relaxing, expanded GdmCl-denaturated state, ignoring the individua

71 dosages in gene-edited cell populations and expands gene editing to chromosomal tracts previously no

72 Expanded genetic repertoires include diverse and previou

73 Mice developed expanded germinal center B lymphocyte populations as in

74 navirus disease 2019 (COVID-19) is a rapidly expanding global pandemic caused by severe acute respira

75 Expanded GPA33(high) Treg cells are suppressive, unable

76 ever, the posterolateral cerebellum has also expanded greatly relative to non-human primates and has

77 Findings further support expanding HCV treatment to all, irrespective of injectio

78 the total Hammersmith Functional Motor Scale Expanded (HFMSE) score, assessed at months 6, 10, and 14

79 using the Hammersmith Functional Motor Scale Expanded (HFMSE).

80 highlight a complex relationship between the expanded Htt allele and Hdac2 with implications for targ

81 Glacial Maximum in the Northern Hemisphere, expanding ice sheets forced a large number of plants, in

82 bleaching, hypoxia) and is expected to have expanding impacts under global warming predictions.

83 s-100,000s ha), persist for decades, rapidly expand in size, be cost-effective, and generate social a

84 NCD services will need to be expanded in Kenya.

85 AMB are also expanded in other chronic infections such as tuberculosi

86 onjugate vaccine (PCV) in 2000 before it was expanded in subsequent years.

87 marks proliferating neutrophils, which were expanded in the blood of melanoma patients and detectabl

88 CAR-NKT cells expanded in vivo, localized to tumors and, in one patien

89 FP is expanding in Florida and the Caribbean but declining in

90 finger is the most common DNA-binding domain expanding in metazoans since the fungi human split.

91 rom human and animal studies is beginning to expand insights regarding neurobiological systems associ

92 guide for plant scientists, especially those expanding into crop research, to capitalise on the disco

93 Species expanding into new habitats as a result of climate chang

94 by which these fibroblasts differentiate and expand is unknown.

95 ovide suggestions on how the Committee could expand its influence by considering measuring variables

96 owledge to become outstanding scientists and expand knowledge through the scientific method.

97 This Review focuses on the rapidly expanding knowledge regarding the implications of 11-oxy

98 evidence for the function of dorsoventrally expanded mandibles and elaborate horns.

99 ndary (~444 Ma) and has been correlated with expanded marine anoxia lasting into the earliest Siluria

100 densely populated cites worldwide motivates expanded measurements and analyses.

101 D improved in states that did versus did not expand Medicaid.

102 We defined expander states as those who expanded Medicaid on or before January 1, 2014, and none

103 tissue, demonstrating its strong capacity to expand memory T-cell pool exhibiting effector memory T-c

104 d a novel cyclical aggregation as a means of expanding MSCs to maintain stem cell functionality.

105 Upon oxidation, the film expands nearly 30% in volume, and the elastic modulus an

106 The rapidly expanding network of roads into the Amazon is permanentl

107 man cerebral cortex necessary for generating expanded neuronal populations.

108 kout mice eventually returned to normal, the expanded NSC pool was maintained in the V-SVZ until old

109 ubsequent skin allografts through indirectly expanded nTreg leading to dominant tolerance without add

110 Furthermore, we found that expanded numbers of identical viral sequences were most

111 ivers for the growing international trend to expand nursing roles.

112 tion of key mRNAs in learning and memory and expand on the notion of dynamic functional RNA states in

113 related to network abnormalities in TLE and expand on the notion of underlying aberrant plasticity.

114 Our results further expand on what is known about ClpXP in the pathogenesis

115 Expanding on a validated and published nongenetic, CF-li

116 high-resolution ion mobility separations and expands on the ability of SLIM to obtain improved separa

117 We expand one of these Cas13a-based methods to detect small

118 editing, and synthetic biology exponentially expand opportunities to enhance the sophistication of im

119 Together, these technologies greatly expand our ability to study and understand specific cell

120 In recent years, many have sought to expand our biochemical and structural understanding of t

121 Furthermore, in silico tools were used to expand our chemical knowledge of compounds observed in s

122 These findings expand our fundamental knowledge of microbial reductive

123 These findings expand our knowledge of IGF-1's role as a novel fibrotic

124 igh dimensional data offers the potential to expand our perspectives on these processes, shedding new

125 These discoveries expand our understanding of how eggshell colour diversit

126 These studies expand our understanding of HSF1-mediated gene repressio

127 t give rise to them, seems likely to further expand our understanding of the neural substrates of mem

128 lavin-dependent hydroxylases and promises to expand our understanding of their catalytic mechanisms.

129 We expanded our analysis across whole proteomes and found t

130 We expanded our analysis to include previously published da

131 al mutations in humanized mouse models, have expanded our opportunities to replicate aspects of human

132 Advances in the last decade have expanded our understanding and appreciation of LNSC hete

133 Since their discovery, giant viruses have expanded our understanding of the principles of virology

134 how this increase in archaeal diversity has expanded our view of the tree of life and early archaeal

135 This will be instrumental in greatly expanding our knowledge of the origins and variation of

136 However, expanding our understanding of Saccharibacteria-host int

137 e regulation of pLGICs at a molecular level, expanding our understanding of their function and elucid

138 ciency provides a large practical impact and expands our ability to study the role protein nitration

139 13 genes whose genotype-dependent expression expands our etiologic understanding of EoE and provides

140 oire of S-acylated proteins has been rapidly expanding owing to development of the chemoproteomic tec

141 ealed that the Si=C bonds are involved in an expanded pai-conjugated system.

142 cade of conformational changes that produces expanded particles primed for viral uncoating.

143 s9 system to delete CD38 (CD38KO) in ex vivo expanded peripheral blood NK cells.

144 hlights the role of whole-genome sequencing, expanded phenotypic drug susceptibility testing, and enh

145 Consequently, there is a need for expanded proactive SSP implementation in the context of

146 Most vaccines in the Expanded Program on Immunization are universal childhood

147 We applied this newly expanded program to an assessment of the U.S. Regional G

148 rinary, bowel, sexual, and hormonal function-Expanded Prostate Cancer Index Composite short-form 26 d

149 PP GCs from different mice expand public BCR clonotypes (clonotypes that are shared

150 The main limitation to expanding quinoa cultivation, however, is the susceptibi

151 de cofactors are important components of the expanding range of asymmetric synthetic techniques.

152 coronavirus disease 2019 (COVID-19) outbreak expanded rapidly throughout China.

153 direct sunshine, and their applications are expanding rapidly enabled by scalable manufacturing.

154 Uptake of antiretroviral treatment (ART) is expanding rapidly in low- and middle-income countries (L

155 Here we expanded RASGRP1 expression surveys in pediatric T-ALL a

156 hich distinct evolutionary strata reflect an expanding region of suppressed recombination [5].

157 mIL-2/CD25 acts not only to expand regulatory T cells (Tregs) but also to increase t

158 verging algal lineages, P. margaritaceum has expanded repertoires of gene families, signaling network

159 ocedures might further the development of an expanded science of mind.

160 arch staff represent acceptable solutions to expand screening, and (iv) whether testing a large perce

161 element (ISRE) promoter motifs, whereas the expanded set of type I IFN-specific ISGs, including proa

162 Tumor models of human PCa epithelia with CAF expanded similarly in mice in the presence or absence of

163 We hope disease researchers will expand social network analyses to more often include spa

164 increase engraftment capacity by seeking to expand stem and progenitor cells.

165 There is also a rapidly expanding subgroup of patients characterized by a high a

166 However, clinical trials with expanded T(regs) in T1D and solid-organ transplant recip

167 In the absence of WRN, the expanded TA-dinucleotide repeats are susceptible to clea

168 ted with either Sapien 3 BE or Evolut R self-expanding TAVR were found in the database.

169 co-occurrence networks points to these three expanding taxa as potential mediators of gut microbiome

170 ns of adenine base editor mRNA and guide RNA expand the applicability of CRISPR-associated gene editi

171 These long-wavelength-absorbing moieties expand the applicability of this powerful method and its

172 patient-collected specimens could be used to expand the availability of gonococcal antimicrobial resi

173 al and clinical communities is imperative to expand the available therapeutics beyond anticoagulants

174 AFF on Treg cells goes beyond its ability to expand the B cell population and is additional to the BA

175 st that combined CXCR4 and PD-1 blockade may expand the benefit of chemotherapy in PDAC and warrants

176 cts that are being developed to increase and expand the clinical benefits of these treatments in pati

177 Future community-level interventions should expand the community health worker workforce, assess gen

178 Thus, we propose to expand the conventional definition of CLL subset 2 to su

179 We confirm and expand the current catalogue of DNA sequence motifs for

180 These findings expand the current models of insulin binding to its rece

181 To explore and expand the current view, we designed and synthesized mol

182 er of studies in the field has allowed us to expand the database more than 5-fold.

183 In summary, the findings presented here expand the documented constellation of di-iron enzyme ca

184 Consideration of DCD in FHF could help expand the donor pool in this subset of critically ill p

185 r interactions is warranted, and will likely expand the existing chemical space of drugs.

186 entity with electric field on the nanoscale expand the existing phenomenology of functional domain w

187 To further expand the functionalities, three modalities of AFMOTs a

188 Our findings expand the genotypic spectrum of congenital NAD deficien

189 These new data sets improve convergence and expand the high-confidence network synergistically.

190 emonstrate a water-incorporation strategy to expand the interlayer gap of alpha-MoO(3), in which wate

191 These findings expand the known diversity of inorganic metabolisms that

192 d with confocal microscopy, we significantly expand the list of epigenetic regulators that impact nuc

193 These results expand the phenotypic and genotypic spectrum of EYS-RD,

194 Our findings also expand the phenotypic spectrum associated with pathogeni

195 Our findings expand the phylogenetic and environmental occurrence of

196 a science techniques of predictive analytics expand the quality and quantity of complex data relevant

197 cription 2 (STAT2) knockout hamster model to expand the repertoire of animal models of CCHFV pathogen

198 Our approach can expand the repertoire of crops for urban agriculture.

199 ther cells and glycans and provides a way to expand the repertoire of glycan-binding proteins for fur

200 ling axis of CARM1-Pontin-FOXO3a and further expand the role of CARM1 in nuclear regulation of autoph

201 nfection, and azithromycin (pediatrics only) expand the role SAARs can play in ASP efforts.

202 active involvement of citizen volunteers to expand the scale of OMP monitoring.

203 explored approach that has the potential to expand the scope of electrosynthesis immensely.

204 n image quality using the graphene grids and expand the scope of EM imaging.

205 vailability of SARS-CoV-2 testing as well as expand the settings in which this testing can be perform

206 ation could increase density and effectively expand the species' range.

207 To expand the TAA landscape of pancreatic ductal adenocarci

208 Second, we expand the taxonomic breadth of tool use to include anot

209 modification of C1q receptor expression can expand the therapeutic window for hNSC transplantation.

210 These experiments expand the toolkit for measuring endogenous dopamine rel

211 s in meso, this feature of EROCOC(17+4) will expand the utility of the in meso method.

212 , where tissues are highly transparent, have expanded the applicability of fluorescence in the biomed

213 e recently, large-scale genomic studies have expanded the clock into a complex network composed of th

214 These new genomes greatly expanded the known pangenomes of many oral clades, inclu

215 tober 2018, the U.S. heart allocation system expanded the number of priority "status" tiers from 3 to

216 eductive dehalogenases throughout the phylum expanded the phylogenetic boundary for potential organoh

217 new Ti(salen) catalyst, which substantially expanded the reaction scope and significantly improved t

218 Here, we expanded the repertoire of known HBoV1 variants by cloni

219 To address this question, we have expanded the toolbox of Forster Resonance Energy Transfe

220 vity with cell-type-specific resolution have expanded the understanding of circuit changes underlying

221 olarity in molecules is a versatile tool for expanding the boundaries of structural space.

222 e potential for multiplexed quantifications, expanding the current toolkit for studying RNA modificat

223 a real-time hybridization study reveals that expanding the effective surface area beyond EFs of ~5 de

224 We show that strategically expanding the existing global MPA network to protect an

225 e U.S. Food and Drug Administration approved expanding the indication for transcatheter aortic valve

226 ic and metal cation functionalities, thereby expanding the key physicochemical properties that are re

227 bed here add information to this hypothesis, expanding the knowledge on molecular relationships betwe

228 gPALB2 or sBRCA1/2 mutations, significantly expanding the population of patients with breast cancer

229 echniques provide powerful tools for greatly expanding the protein engineering toolkit.

230 stability in the hybrids used in this study, expanding the range of functional traits estimated by hy

231 be applied to imaging many other metal ions, expanding the range of the current genetically encoded f

232 he Triassic ornithodiran clade Lagerpetidae, expanding the range of this group into Africa and provid

233 tegrated, ultralow-power and fast actuation, expanding the repertoire of technological applications o

234 ntrols the phase and period of oscillations, expanding the role of this pathway beyond its classical

235 correlative light/electron microscopy, thus expanding the scope of cryogenic cellular imaging.

236 to vaborbactam, efforts were directed toward expanding the spectrum to allow treatment of a wider ran

237 favorable diol formation pathway, created by expanding the substrate scope of the carboxylic acid red

238 al methods as well as the designof new ones, expanding the toolbox for discovery and optimization of

239 eophilic trappings previously reported, thus expanding the types of product accessible from this clas

240 r reprogramming and organoid engineering are expanding the use of human neuronal models in vitro.

241 spread of nonselected genetic variation and expands the adaptive potential of microbial populations.

242 This document expands the cardiac arrest resuscitation system of care

243 The aggregate of these results expands the catalogue of qubit materials to Ni(2+)-based

244 dification of phage libraries, which greatly expands the chemical space amenable to phage display.

245 LUCS greatly expands the designable structure space and offers a new

246 The catalog expands the known phylogenetic diversity of bacteria and

247 The Miscanthus genome expands the power of comparative genomics to understand

248 olyinosinic-polycytidylic acid significantly expands the proportion of proliferating CD8(+) T cells i

249 SPACE expands the range of possible DNA sequence alterations,

250 es the requirement for motif specificity and expands the repertoire of substrates.

251 Thus, REPAIRx markedly expands the RNA editing toolkit and illustrates a novel

252 This work expands the scope of ribosome-mediated polymerization, s

253 d neurological findings and medical concerns expands the spectrum of genetic disorders resulting from

254 Our work expands the spectrum of Weyl matter into semiconductors

255 catalyzed electrochemical allylic alkylation expands the synthetic scope of cross-coupling reactions

256 ondition to what is achievable with CID, CIT expands the types of manipulation in single live cells t

257 As a cluster expands, the predictions improve while the lead-time for

258 from quiescence and ventral nerve cord glia expand their membranes.

259 ptured using autogenerating polynomials that expanded their optimal selection of terms using informat

260 s have broadened their editing capabilities, expanded their targeting scope and improved editing spec

261 ste perception in fruit flies, significantly expanding their scope of action.

262 and cultured as stem/proliferative cells to expand them and cover the scaffold surface with the cryp

263 We also expanded these observations with replication analyses in

264 We expand this framework to future directions including the

265 We expand this modeling approach by incorporating direction

266 We have now expanded this technology to adeno-associated viral vecto

267 Since 2017, CARD has expanded through extensive curation of reference sequenc

268 ables the as-formed high-index grain seed to expand throughout the entire Cu foil.

269 are known to depredate nests, and have been expanding throughout the distributed range of wild turke

270 subapical stolon region divide and radially expand to further differentiate into starch-accumulating

271 etic design and optimization approach can be expanded to apply to other cardiovascular disease target

272 be leveraged therapeutically and potentially expanded to BRG1-mutant cancers in other tissues.

273 sing superutilizer intervention and has been expanded to cities around the country.

274 e for data annotation has been substantially expanded to enhance biological interpretations of querie

275 and Viooy, and onto Streymoy from which they expanded to Eysturoy and Vagar.

276 Since that time, RGD has expanded to include a wealth of structured and standardi

277 for muscle-invasive and advanced disease has expanded to include immunotherapy with checkpoint inhibi

278 he investigation of erythropoietin (EPO) has expanded to include potential nonhematopoietic roles in

279 y for descending aortic pathologies, and has expanded to new patient cohorts, including the elderly.

280 haviour could benefit greatly from generally expanding to incorporate these new insights.

281 ell lung cancer (NSCLC) in light of the ever-expanding toolbox of targeted therapies and immune-check

282 ential for the scientific community with its expanding toolbox.

283 ment, and ongoing clinical trials to provide expanded treatment options.

284 Finally, IL-2/alphaIL-2 complex-expanded Treg cells could be recalled upon allergen chal

285 Strategies to expand tuft cells might be developed for treatment of CD

286 The expanded type I IFN-specific response includes proapopto

287 evity in the tropical lowlands are likely to expand under future drier and especially warmer climates

288 By identifying where irrigation can be expanded under a warmer climate, this work may serve as

289 activated in stem and progenitor cells, LSCs expanded under chemotherapy-induced stress.

290 etection range of the sensor with b2LOxS was expanded up to 10 mM.

291 uggest new therapeutic strategies that would expand upon the limited symptomatic treatments currently

292 when synthesizing peptide-based drugs and to expand upon the recently published short communication r

293 ction: memory T cells secreted cytokines and expanded upon antigen re-encounter, whereas memory B cel

294 Perhaps the greatest challenge to expanded use of MPAs is the perceived trade-off between

295 tral site polymorphism is expected to confer expanded "UV-blue" spectral sensitivity and is estimated

296 coupled with blockade of TNFalpha signaling, expanded VAT-Treg cells, resulting in protection from in

297 d virus and the presence of both unbound and expanded virus particles suggests receptor binding initi

298 her investigation to identify strategies for expanding water security in the face of drought and othe

299 Recognizing that this field is rapidly expanding, we aim to provide a state-of-the-art review o

300 The use of cannabis is rapidly expanding worldwide.