ライフサイエンスコーパス: experimental

1 Experimental analysis of the DLC1 mutants indicated 7 of

2 changes are validated by targeted and global experimental analysis.

3 Here, we propose a model that bridges experimental and bioinformatics concepts using the Oxfor

4 NMP and different perfusate compositions in experimental and clinical models.

5 Studies in models of experimental and clinical nephropathies have described a

6 Here, we present an experimental and computational methodology that uses scR

7 b portal and a standalone R package to allow experimental and computational scientists to easily navi

8 We carry out an experimental and computational study that exploits the n

9 e health state categories, despite disparate experimental and disease contexts.

10 Consistent with prior experimental and human studies, GFAP, was highest at 6 h

11 Experimental and in situ spectroscopic monitoring techni

12 Experimental and mathematical modeling analyses suggest

13 ly influenced by electrolyte pH, and it used experimental and modeling approaches to elucidate such i

14 However, recent experimental and modeling studies have begun to question

15 f an oncogenic KRAS4b, we used complementary experimental and molecular dynamics simulation approache

16 ses toward people's own groups shown in both experimental and natural settings.

17 Empirically, we synthesize experimental and observational evidence from studies of

18 osphoric acid was investigated by a combined experimental and statistical modeling approach.

19 Here, the experimental and theoretical analyses are focused on sin

20 Using experimental and theoretical analysis of AWC(ON), a well

21 anization of the olivary nucleus and a novel experimental and theoretical approach to study electrica

22 Using experimental and theoretical approaches including magnet

23 The experimental and theoretical approaches of the optical r

24 etal-oxide photoanodes remains a significant experimental and theoretical challenge.

25 adaptive behavior could benefit from renewed experimental and theoretical investigation of more power

26 Both experimental and theoretical studies have attempted to d

27 scription must be considered for appropriate experimental and therapeutic use of these reagents.

28 ting K(v) spatially has remained conceptual, experimental, and/or poorly constrained.

29 Experimental animal models demonstrate that maternal imm

30 rol transport, and prevented liver injury in experimental animal models.

31 gold standard of rigorous standardization in experimental animal research, we recommend the use of sy

32 Th2 inflammatory and profibrotic pathways in experimental animals provide a preliminary, mechanistic

33 sufficient numbers for multiple clinical and experimental applications.

34 In this study, we designed an experimental approach based on potentiometric titrations

35 , Seress and colleagues take on an intensive experimental approach to test whether one potential stre

36 Using a novel experimental approach, we demonstrate that reducing pulm

37 Altogether, these computational and experimental approaches allow assessment of critical mic

38 is-clustering has been hindered by a lack of experimental approaches capable of detecting and quantif

39 the current study, we integrate a number of experimental approaches to build a model that provides i

40 , we combined computational, analytical, and experimental approaches to investigate the potential mec

41 The experimental arm received adjuvant cetuximab.

42 Urinary TXM was reduced by 35% in both experimental arms.

43 oligodendrocytes against inflammation in the experimental autoimmune encephalomyelitis (EAE) model of

44 In female mice with experimental autoimmune encephalomyelitis (EAE), a murin

45 PCs) within the spinal cord leptomeninges in experimental autoimmune encephalomyelitis (EAE), an anim

46 focus of MS research using the animal model experimental autoimmune encephalomyelitis (EAE), substan

47 Using an animal model of MS, experimental autoimmune encephalomyelitis (EAE), we show

48 Here, using experimental autoimmune encephalomyelitis, an establishe

49 ection and confers heightened sensitivity to experimental autoimmune encephalomyelitis.

50 Finally, we review challenges to conducting experimental camera trap studies.

51 is severely attenuated and the incidence of experimental cerebral malaria is significantly decreased

52 e human vasculature represents an unresolved experimental challenge.

53 Experimental challenges posed by these properties have g

54 dium berghei ANKA-infected C57BL/6J mice, an experimental CM model.

55 ssociate with increased disease index of the experimental colitis in mice.

56 A on the gut-brain axis in rats subjected to experimental colitis induced by oral administration of d

57 The combined experimental, computational, and dynamic trajectory stud

58 d type of reducing agent using a synergistic experimental-computational approach.

59 )] was characterized in detail by a combined experimental/computational approach using X-ray diffract

60 d is described which is less affected by the experimental conditions in a given measurement system.

61 ify active pathways or modules under certain experimental conditions or phenotypes.

62 s overestimation is observed under different experimental conditions, even when the boundary is forme

63 al efficiency under various physiological or experimental conditions.

64 potency and generalizability across various experimental conditions.

65 ture in the gas phase is highly dependent on experimental conditions.

66 ally in terms of statistical reliability and experimental confounds.

67 ons to reward-biased decision-making and put experimental constraints on the neural implementation of

68 ere we show that exposure of the skin to the experimental contact allergen DNFB results in a displace

69 ach presents a promising avenue to integrate experimental data and make regional-scale predictions of

70 two approaches, the similarities between the experimental data are assessed by means of the Euclidean

71 al network simulations, until further direct experimental data become available.SIGNIFICANCE STATEMEN

72 Our analysis demonstrates how small-scale experimental data can be leveraged to derive expectation

73 The obtained experimental data demonstrate a highly sensitive and rel

74 olated limit of detection of 2.2 CFU/ml from experimental data in buffer solution with no sample prep

75 The experimental data indicates the behavior of 4 and P towa

76 del that can predict NN thermodynamics where experimental data is scarce or absent.

77 488 growth conditions corresponding to 3,221 experimental data points were simulated.

78 ree-dimensional structures associated to the experimental data provided by Hi-C maps.

79 Experimental data reveal that the CIE coordinates within

80 , respectively, were trained using the large experimental data set, which enabled the generation of a

81 Experimental data suggest that IRE ablation produces lar

82 confirmed to be mediated by ion channels and experimental data suggests an insignificant thermal cont

83 cular basis of telomeropathies and highlight experimental data that illustrate how genetic mutations

84 dels were sequentially built and adjusted to experimental data to describe changes in concentration i

85 We analyze the experimental data using single-cell tracking to calculat

86 with the invariance properties, we compared experimental data with computational modeling results.

87 results in reasonable accord with available experimental data, after correcting for differences in n

88 a birth-death model with both synthetic and experimental data, and show that we can robustly infer m

89 e 200 ns simulations, validated by available experimental data, reveal processes and mechanisms by wh

90 Using both simulated and experimental data, we show that this model improves both

91 s were analyzed in comparison with available experimental data.

92 (NS) and cryo-electron tomography (cryo-ET) experimental data.

93 the molecular structure without the need for experimental data.

94 Using both synthetic and experimental datasets for comparison, we perform FLOW-MA

95 We consider a broad array of simulated and experimental datasets to demonstrate the effectiveness o

96 ods are based on either simulated or limited experimental datasets.

97 We present an experimental demonstration of passive, dynamic thermal r

98 ation (RMSD) of 1.24 angstrom on a set of 50 experimental density maps which was tested by the Phenix

99 describe a combination of computational and experimental design of cobaltocene metallo-cations that

100 Power analysis becomes an inevitable step in experimental design of current biomedical research.

101 Study 2 (n = 425) used an experimental design, and found further support for emoti

102 rent European countries and sharing the same experimental design.

103 circadian rhythms were controlled for in the experimental design.

104 " (RB), or one of the more specialised named experimental designs described in textbooks on the subje

105 uit larger sample sizes; and use single case experimental designs for better pragmatic and explanator

106 different cellular populations from diverse experimental designs.

107 Established protocols for experimental detection and computational inference of CN

108 Experimental developments continue to challenge the theo

109 ible for subsidies (>400% FPL) using a quasi-experimental difference-in-differences approach.

110 y, we explored possible explanations for the experimental discrepancy.

111 iver in analogy to what is observed in other experimental disease paradigms.

112 tional monolayer detection limits in a total experimental duration that is 2 orders of magnitude less

113 in two of the most commonly used designs in experimental economics.

114 acking data, we analyze multiple natural and experimental ecosystems (marine plankton, intertidal mol

115 Experimental evidence (e.g., X-ray crystallography, elec

116 to show that the consideration of additional experimental evidence (such as information on biotransfo

117 We consider the varied experimental evidence arising from the application of X-

118 from homologous genes or proteins for which experimental evidence exists.

119 s and high-throughput sequencing, we provide experimental evidence for the developmental importance o

120 as functions of ATP concentration, providing experimental evidence for the predicted ensemble behavio

121 Experimental evidence in rodents and humans suggests tha

122 MUV can be attenuated by in vitro passaging, experimental evidence supporting the role of specific ge

123 The experimental evidence that Adhesion G Protein-Coupled Re

124 ate parameters of HGT and selection from our experimental evolution data.

125 Experimental evolution has also shown that the relative

126 otential limitations that warrant a thorough experimental examination of its validity.

127 lain underlying fundamental concepts through experimental examples with the RNA-binding protein Puf4.

128 represent a challenging frontier for further experimental exploration.

129 Experimental exposure of White Ibises (Eudocimus albus)

130 regard to its dependency on several critical experimental factors, including the time interval betwee

131 In many cases, it is unclear which experimental features or model assumptions are necessary

132 servations urge a crucial revisit of various experimental findings and theoretical models--including

133 This mechanism was supported by several experimental findings obtained using biochemical methods

134 hile the proposed models harmonize with many experimental findings, gaps and inconsistencies in our u

135 Molecular dynamics simulations reinforce the experimental findings, showing that anionic AuNPs do not

136 data were found to be in good agreement with experimental findings.

137 While animal models provide the experimental flexibility to analyze mechanisms of remyel

138 this study demonstrates its effectiveness in experimental fluid mechanics and verifies it by simulati

139 for [Formula: see text] This paper paves the experimental framework to further explore chip-scale axo

140 Our experimental games confirm the existence of both 'lone w

141 frequency of oscillating field applied in an experimental geometry resembling that of liquid crystal

142 cally trace the provenance of knowledge from experimental ground truth to gene function predictions a

143 ypertension (88 [27%] of 332 patients in the experimental group vs 67 [20%] of 329 patients in the st

144 observed in the n3 FA content in egg yolk in experimental groups, as well as all PUFA (polyunsaturate

145 resource models is necessary for reproducing experimental growth curves of the baker's yeast Saccharo

146 sks in just over 100 hundred experiments (~8 experimental hours) - a factor of 5x faster than our pre

147 unction by improving Nrf2/nNOS expression in experimental hyperglycemia.

148 Human and experimental in vivo and in vitro studies show that the

149 atural cases in animals alongside successful experimental infections of pets, such as cats, ferrets a

150 nical approach in cancer therapy but also an experimental injury model used to examine mechanisms of

151 -life by quantifying the rate of decay after experimental intervention (e.g., pulse labeling).

152 Here, we report an experimental investigation of BP membrane in osmotic ene

153 it can provide a useful resource for further experimental investigation of DNA 6 mA modification.

154 l D. melanogaster CS helps set the stage for experimental investigations into their responsivity, sen

155 spectrometry improves the time resolution of experimental investigations into these processes and ena

156 However, very limited experimental investigations on phonons in these systems

157 We combine experimental investigations with computational simulatio

158 ntext influence dispersal dynamics in simple experimental landscapes composed of homogeneous habitat

159 Finally, we generate the most complex experimental lineage tracing dataset to date, 34,557 hum

160 possibility that such processes can explain experimental live-cell imaging data measuring distances

161 in good agreement with the best established experimental measure of free volume.

162 oximate Bayesian statistical inference, with experimental measurements carried out after murine aeros

163 conditions using a novel, to our knowledge, experimental methodology called constrained drop surfact

164 low-cost platform, Chi.Bio facilitates novel experimental methods for synthetic, systems, and evoluti

165 Experimental methods to determine disease related miRNAs

166 ptive evolution steps to address the lack of experimental methods to systematically identify such ext

167 Contrary to commonly used experimental methods, microscopy data are fast processed

168 Previous work suggests that an experimental MI can accelerate atherosclerosis via monoc

169 All mice subjected to experimental MI had significantly reduced left ventricul

170 udies illustrate the power of using multiple experimental modalities to model and test therapies for

171 n in mice provides an efficient cause-effect experimental model to understand the mechanisms of direc

172 We relied on a wild boar experimental model, analysing 24 wild-born specimens rai

173 Studies in experimental models and humans have identified 9 highly

174 arians, flatworms from order Tricladida, are experimental models of stem cell biology and tissue rege

175 on are incompletely understood, with limited experimental models to investigate the mechanisms drivin

176 cific anatomical environments, functions and experimental models.

177 eptor modulators regulate podocyte injury in experimental models.

178 it the AIM2 inflammasome was confirmed in an experimental mouse model of stroke.

179 e provide here an overview of the studies in experimental mouse models that try to address this quest

180 against hypoxia-associated IUGR, we used an experimental murine model to determine whether such effe

181 taminase inhibitor ameliorated disability in experimental neuroinflammation.

182 ral activity of Gdf5 regulatory sequences in experimental OA following destabilisation of the medial

183 However, the direct experimental observation and transformation kinetics of

184 The experimental observation of non-trivial surface states i

185 Here, experimental observations and molecular dynamics simulat

186 The experimental observations are supported by computational

187 This reversal mirrors some recent experimental observations, and provides a robust criteri

188 esive properties are unable to explain these experimental observations, instead underestimating the m

189 nfirm the essential elements of the previous experimental observations, taken as support for the HCO3

190 ically consistent interpretation of numerous experimental observations.

191 lled sequential activity are consistent with experimental observations.

192 erequisite for the statistical evaluation of experimental outcomes.

193 Experimental overproduction of a type 3 secretion system

194 Experimental P(ion) values were high enough to explain o

195 ctomy due to complications and after placing experimental pancreatic sutures in the pancreatic tail o

196 Although this process has been an experimental paradigm for reproduction and sperm chemota

197 Therapeutic strategies and experimental paradigms should operate under the assumpti

198 Under optimized experimental parameters by factorial design, the biosens

199 Without extensive optimization of experimental parameters, we were able to quantify down t

200 c-SIP performance depends on optimization of experimental parameters.

201 s of intrahippocampal circuitry derived from experimental pathway-tracing experiments.

202 clinically on a daily basis during a 20-day experimental period and blood samples were collected for

203 ated the effect of Msx2-null mutation during experimental periodontitis in mice.

204 Experimental periodontitis was induced for 30 days in wi

205 ns with similar methods and estimations from experimental perturbations.

206 uced a tension fall at a rate similar to the experimental phase II.

207 To address this issue, we established an experimental pipeline for comprehensive profiling of sma

208 Thus, this experimental platform allows the study of human tumor in

209 membrane vesicles (GPMVs) are a widely used experimental platform for biochemical and biophysical an

210 failure and highlight exercise as a valuable experimental platform for the discovery of much-needed n

211 idate the BPRN model as a robust preclinical experimental platform to address current barriers to imp

212 This experimental platform was further exploited for studying

213 ites, analysing a combination of local-scale experimental plot data and geographic-scale data contain

214 to develop robust, reliable, and model-based experimental probes; recruit larger sample sizes; and us

215 But till now, the experimental progress in this direction in Weyl semimeta

216 e as the new starting point for clinical and experimental purposes.

217 ng rapid subunit degradation with orthogonal experimental readouts.

218 The experimental realization using photolithographically fab

219 ivity and were compared to each other and to experimental recordings of visual-driven neural activity

220 Over 50 000 experimental records for anti-retroviral agents from ChE

221 In the field, experimental reefs supplemented with mangrove leaves gro

222 By using this experimental regime in conjunction with cytoplasmic extr

223 alibrations are precluded because of lack of experimental relative permeability data.

224 explicitly accounts for variability between experimental replicates.

225 l study was performed which corroborated the experimental results and provided insight into the host-

226 Our simulations match the experimental results and show that arterial pulsations o

227 The simulation framework, validated with experimental results and supported by the theoretical pr

228 The experimental results are well explained through analytic

229 The experimental results disagree with some theoretical pred

230 Based on recent experimental results for single cells, we derive a minim

231 menological model that nicely reproduces the experimental results including the induced amplitude and

232 h and its implementation as well as presents experimental results obtained using simulated and real c

233 Experimental results on three influenza datasets show th

234 The experimental results revealed that the average particle

235 Our experimental results show that csdAB and csdCD are invol

236 Experimental results show that IsoFun significantly outp

237 We report experimental results showing the pressure dependence of

238 Theoretical calculations and experimental results verify the existence of bifunctiona

239 the confinement length L, in agreement with experimental results, and provides the basis for a more

240 In order to complement the experimental results, the in silico methods were further

241 Using simulated and experimental RNA-sequencing data sets, we show that GSEC

242 Experimental RV infection induces bronchial mucosal eosi

243 Reproducible research is the bedrock of experimental science.

244 that are protective against mortality during experimental sepsis.

245 .5, 1.0 mg) across three separate fixed dose experimental sessions.

246 se of CKD have been demonstrated only in the experimental setting.

247 By developing an experimental setup and analysis tools, we show that, wit

248 ylated and biotinylated peptides in a single experimental setup.

249 nthesis of alkenes using a one-pot, two-step experimental setup.

250 Experimental sleep-wake disruption in rodents and humans

251 and the noise in the available heterogeneous experimental sources of information.

252 first-principles simulations of all critical experimental steps, distinctive roaming signatures were

253 r lineage tracing in settings where existing experimental strategies cannot be used.

254 We here aimed at proposing a new experimental strategy that transfers this logic into a s

255 ures that differ significantly from previous experimental structures of C99, providing an example of

256 Through experimental studies and computer simulations, we succes

257 Experimental studies following the theoretical predictio

258 past decade, a broad range of laboratory and experimental studies have complemented field observation

259 Experimental studies investigating the drivers of LLPS h

260 evolution provide an important link between experimental studies of virus evolution and large-scale

261 Many experimental studies suggest that animals can rapidly le

262 Because of the costs of clinical and experimental studies to treat and understand heart funct

263 e, validated this model for conducting these experimental studies with human strains.

264 This situation presents difficulties for experimental studies, drug development, and other future

265 In experimental studies, we used a monoclonal antibody to u

266 re we report on a combined computational and experimental study about ultrafast diffractive imaging o

267 y in naturally infected animals and only one experimental study demonstrating susceptibility and evid

268 A quasi-experimental study included patients with active injecti

269 Here, however, we show that if the experimental subject is inferring the reward distributio

270 Our results provide rare experimental support for the strong negative effects of

271 We utilized a high-throughput full-factorial experimental system and the model photosynthetic microor

272 Using a two-species experimental system of the flour beetles Tribolium casta

273 We used an ecosystem-level experimental system to independently control potential a

274 Experimental systems aimed at testing various sorts of m

275 , mainly due to lack of brain-representative experimental systems to study HIV-CNS pathology.

276 Using three well-studied experimental systems-encompassing plants, protists, and

277 treatments in combination over 18 months of experimental tank rearing.

278 CD is an experimental technique that can provide protein structur

279 st decade has seen a dramatic advancement of experimental techniques and data analysis methods that h

280 Here, in an effort to make better use of the experimental techniques we have at our disposal, I propo

281 Despite being characterized by various experimental techniques, the atomic-level contributions

282 to its being used in combination with other experimental techniques.

283 ditive layer manufacturing (3D printing) and experimental testing are implemented to justify the eval

284 Experimental testing of 62 screening candidates yielded

285 licating nasal cavity structures and for the experimental testing of nasal function.

286 sion prediction approach in inverse mode and experimental thermal diffusion data.

287 Experimental thermoreflectance measurements were perform

288 ental concepts regarding lipid peroxidation, experimental tools for the study of such processes, as w

289 y network is far from being understood since experimental tools that measure neural activity across t

290 Complementing these experimental tools, co-polymers theoretical methods are

291 Taguchi method reduced the time required for experimental trials compared with a grid method and sugg

292 Across experimental trials, growth rates differed among family

293 ade viral tracers with practical guidance on experimental uses.

294 oducing a filtered list of genes for further experimental validation as well as several accompanying

295 Some experimental variables such as pH, DES solvent type and

296 fects models adjusted for repeated measures, experimental variables, age, and inter-individual variab

297 controls to minimize false discoveries, and experimental variations among biological/technical repli

298 The experimental whitening gels did not affect cell viabilit

299 Building on previous modeling and experimental work suggesting that striatal projection ne

300 Complementary experimental (X-ray absorption spectroscopy) and theoret