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1 tastatic cancer, even in the same patient or experimental model.
2 nce of subsequent cardiac vasculitis in this experimental model.
3 to develop an alternative, non-select agent experimental model.
4 and chose Pacific oyster Magallana gigas as experimental model.
5 ons in liver function and structure using an experimental model.
6 uids (with and without nicotine) on the same experimental model.
7 h improved pathophysiologic properties as an experimental model.
8 image pancreatic inflammation in a relevant experimental model.
9 the procedure provides a unique clinical and experimental model.
10 oped and analyzed an integrated mathematical-experimental model.
11 GC projection depends on the duration of the experimental model.
12 e also shown endocrine-disrupting effects in experimental models.
13 nct effects on virus phenotypes in different experimental models.
14 o enhanced metastasis and chemoresistance in experimental models.
15 rted by clinical data and the translation to experimental models.
16 in atherosclerosis is based on findings from experimental models.
17 regarding senescence in the human kidney and experimental models.
18 ll pathology and acute pancreatitis in mouse experimental models.
19 disciplines, encompassing human studies and experimental models.
20 liver fibrosis but also vessel remodeling in experimental models.
21 coactivators, are drivers of tumor growth in experimental models.
22 at autoimmune and inflammatory conditions in experimental models.
23 ble vascular scaffold [BVS]) using different experimental models.
24 ed informatics or can only be used in single experimental models.
25 sm of the virus and the paucity of tractable experimental models.
26 of various modes of cell death in a range of experimental models.
27 valuated for its anti-inflammatory action in experimental models.
28 ecrease mortality and morbidity after ICH in experimental models.
29 nd anti-senescence responses in a variety of experimental models.
30 s on using human tissues and supplemented by experimental models.
31 y have been hampered by a paucity of in vivo experimental models.
32 ide (NO)-dependent vasodilator properties in experimental models.
33 Both aspects are challenging to capture in experimental models.
34 d the functional role of CST was explored in experimental models.
35 , various prion strains can be propagated in experimental models.
36 effects of altered fatty acid metabolism in experimental models.
37 modulation of spinal networks in accessible experimental models.
38 cific anatomical environments, functions and experimental models.
39 fts we constructed dedicated classifiers for experimental models.
40 eptor modulators regulate podocyte injury in experimental models.
41 extensively studied in cancer cell lines and experimental models.
42 suitable for studying neutrophil function in experimental models.
43 e due to the absence of truly representative experimental models.
44 cardioprotective effects in a broad range of experimental models.
45 have been found to reduce neuronal death in experimental models.
47 Using the mouse tyrosinase (Tyr) locus as an experimental model, a gene whose mutations are associate
55 anti-BP180 IgE has been suggested in various experimental models and by the successful use of omalizu
56 ion of HDAC6 improved established PAH in two experimental models and can be safely given in combinati
57 interference with tumor detection; however, experimental models and clinical studies have shown a co
59 nding off-target impacts of IL-2C regimes in experimental models and for considering how IL-2 may con
60 gated tagraxofusp resistance in patients and experimental models and found that it was not associated
67 atient data and advances in imaging methods, experimental models and multiomics-generated big data.
69 emain elusive due to the lack of appropriate experimental models and precise molecular mechanisms.
70 ntify knowledge gaps, appraise the available experimental models and propose future directions for th
72 as a theoretical framework to bridge between experimental models and scales, with the aim of separati
73 tudies in humans and genetically manipulated experimental models and that exploit awareness of the lo
74 d in human thyroid cancer and thyroid cancer experimental models and their effects on Pax8 and Bcl2 w
75 tation of research data generated in various experimental models and to promote cross-disciplinary co
77 f infection has been hampered by the lack of experimental models, and until now, a mouse roseolovirus
78 es that the ferret is a potentially valuable experimental model animal for understanding the evolutio
79 also highlights the strengths of a combined experimental-modeling approach to unambiguously understa
82 In this review, we will discuss how these experimental models are carving a way for understanding
83 , which result in high rates of lethality in experimental models, are thought to include multicellula
88 Indeed, planarian flatworms were used as experimental models decades before Caenorhabditis elegan
92 are difficult to observe due to the lack of experimental models easily combined with theoretical mod
97 This study evaluated cardiac function in an experimental model following exposure to e-cigarettes.
101 metic co-culture systems provide a promising experimental model for investigating the functional role
102 cted to oxygen-glucose deprivation (OGD), as experimental model for ischemic conditions, were treated
103 onhuman primates currently serve as the best experimental model for Lyme disease because of their clo
104 Cs) in the Drosophila ovary are an important experimental model for the study of epithelial stem cell
106 inogeniculate synapse, has become a powerful experimental model for understanding how circuits in the
111 xtensively studied, but the absence of valid experimental models has hampered our understanding of th
114 dge of their driving defects and the lack of experimental models have impaired clinical successes.
116 ll as for numerous application, e.g. for the experimental modelling in a lab of natural processes.
120 ultiple developmental contexts, the range of experimental models in which each of the steps can be ex
122 tegration of epidemiology-based data with an experimental model increases the evidence that prenatal
123 n to occur in response to Plasmodium spp. in experimental model infections, and in human malaria.
125 better understanding of EV-D68 infection in experimental models may allow for better prevention and
126 gh eNOS derangement has been demonstrated in experimental models, no studies have directly shown that
127 ture represents, to our knowledge, the first experimental model of a G-protein-coupled receptor-G-pro
129 l to their medication can be explained in an experimental model of acetylcholine receptor deficiency,
131 the renoprotective effects of puerarin in an experimental model of advanced DN and provide a molecula
133 ut genetic and environmental confounders, an experimental model of allergic asthma in mice was used.
135 h epicardial remodeling was reproduced in an experimental model of atrial cardiomyopathy in rat and i
137 sults show that the bile duct ligation (BDL) experimental model of cholestasis leads to rapid and sig
140 med in vivo two-photon calcium imaging in an experimental model of Dravet syndrome (Scn1a+/- mice)-a
146 importance of the IL-6-STAT3 pathway in our experimental model of group 2 PH and human patients.
151 nteraction between sex and weight gain in an experimental model of lung allergic inflammation induced
152 e ability for early metastatic seeding in an experimental model of lung metastasis, indicating that h
155 hese observations has been extended using an experimental model of multiple sclerosis [experimental a
157 his question, we developed a virtual reality experimental model of neighborhood disadvantage and affl
166 n and establish a proof of principle whereby experimental modelling of a disorder can help mechanisti
168 late phases of the inflammatory response in experimental models of acute and chronic renal IRI using
174 erimental Psychopathology approach, based on experimental models of anxiety in healthy subjects, can
177 t that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior i
179 o reverse or slowdown disease progression in experimental models of autoimmune encephalomyelitis-, SO
182 GHRH and its receptors are expressed in experimental models of BPH, in which antagonists of GHRH
184 energetic metabolism, was found elevated in experimental models of cancer, starvation, diabetes, and
187 catheter-induced clotting assays and rabbit experimental models of catheter occlusion and arterioven
188 he known neuroreparative actions of IL-33 in experimental models of central nervous system (CNS) inju
189 om patients with cholestatic disease, in two experimental models of cholestasis, as well as in human
190 s in hippocampal and neocortical circuits in experimental models of chronic temporal lobe epilepsy.
191 ced expression of noncanonical WNT-5A in two experimental models of COPD and increased posttranslatio
194 dpoints, provide quantitative endorsement of experimental models of disease, and could be incorporate
200 ms of pathology, both clinically and in many experimental models of FGR, impaired uteroplacental vasc
201 s were also tumorigenic and prometastatic in experimental models of HCC, and eight of these mapped to
203 , the use of Nox1(-/-) and Nox1(+/+) mice as experimental models of human responses demonstrated a cr
204 e 2 diabetes (T2D), and cognitive decline in experimental models of IH patterned after O2 profiles se
205 Here, we used theoretical considerations and experimental models of immune responses in vitro and in
210 ned cell lines constitute a resource of live experimental models of mutational processes, which poten
211 icacy of mitochondrial-targeted therapies in experimental models of neurodegenerative disease and CNS
213 d neurorestorative effects across a range of experimental models of neuronal degeneration, and, recen
221 inical features, termed the "PTEN-opathies." Experimental models of PTEN pathway disruption uncover t
223 Intricate lineage-tracing strategies and experimental models of regenerative stress have revealed
224 arians, flatworms from order Tricladida, are experimental models of stem cell biology and tissue rege
226 antithrombotic effects of such nutrients in experimental models of thrombosis or analyzed biomarkers
232 the success of a few wild tobacco species as experimental model organisms have resulted in growing kn
235 otein synthesis and breakdown with two basic experimental models, primed-dose continuous tracer infus
240 iled assessments of tumor growth in subtyped experimental models revealed that a highly invasive grow
241 chedules within the STAR Methods section and Experimental Models section of the Key Resource Table.
247 e events have been unsuccessful; findings in experimental models suggest that CD8+ T cells drive dise
249 silicon photoanodes and photocathodes as the experimental model system and described a systematic ana
250 this study, we developed a computational and experimental model system to address this challenge and
252 by taking advantage of a well-characterized experimental model system, in which auxotrophic genotype
253 on has allowed for a wide range of different experimental model systems designed to explore different
255 alysis of multiple samples, or for non-human experimental model systems with no reliable databases of
256 atomistic interpretation of the behavior of experimental model systems, such as the degree of lipid
258 Thus, ALX receptor deficiency serves as an experimental model that defines multiple cellular and mo
260 te how ZIKV leads to microcephaly in a novel experimental model that mimics early brain development.
262 ephalomyelitis in nonobese diabetic mice, an experimental model that resembles several aspects of SPM
263 he bioaccessibility of polyphenols, using an experimental model that simulates human gastrointestinal
264 umans to mosquitoes, and have established an experimental model that will accelerate the development
265 ogression, which requires the development of experimental models that aid better deconstruction of th
266 oals in mind, we discuss the need to develop experimental models that better capture the contexts tha
267 nologies to better target ILC2s and engaging experimental models that better manifest both acute infe
268 the appearance of any disease symptoms, yet experimental models that can be used to examine clonal a
270 gates in purified properdin preparations and experimental models that do not allow discrimination bet
271 coring the importance of developing improved experimental models that holistically encompass the meta
272 ytosing RPE cells, utilizing three different experimental models: the human-derived RPE-like cell lin
277 This organoid culture system provides an experimental model to investigate human placental develo
278 in the bee gut and that holds promise as an experimental model to study bacteria-phage dynamics in n
279 enabled by ODC1 interference provides a new experimental model to study mechanisms and consequences
280 This novel cell culture system provides an experimental model to understand how telomerase is regul
281 n in mice provides an efficient cause-effect experimental model to understand the mechanisms of direc
282 cific populations, and how we have developed experimental models to decipher the interactions between
283 hythmic strategy warrants further testing in experimental models to evaluate its clinical potential.
284 y in multiple clinical contexts, and we used experimental models to identify mechanisms by which suPA
285 on are incompletely understood, with limited experimental models to investigate the mechanisms drivin
287 In vitro cancer cell cultures are facile experimental models used widely for research and drug de
289 w how information from related and unrelated experimental models was translated to a clinical setting
291 ription polymerase of T7 bacteriophage as an experimental model, we identify hundreds of new replicat
292 ia isolated from an HIV/AIDS patient, as our experimental model, we show that the proteins are ATP an
293 veloping a classification system tailored to experimental models, we have uncovered subtype-specific
296 major obstacle is the lack of an appropriate experimental model which incorporates genetic susceptibi
297 n the ability to reproduce already existing 'experimental models', which in turn, have an unclear acc