ライフサイエンスコーパス: extensive

1 Taken together, the results provide an extensive 5hmC map across diverse human tissue types tha

2 Extensive ab initio calculations reveal that the measure

3 Extensive aberrant methylation of DNA is broadly documen

4 ic strategy provides concise and potentially extensive access to this valuable class of natural compo

5 Developing arbors have extensive acentrosomal microtubule dynamics, and here, w

6 al B cells, malignant plasma cells showed an extensive activation of regulatory elements, in part aff

7 was the first national study to incorporate extensive activity data reported to the GHGRP, including

8 Protein stability measurements demonstrate extensive activity-stability tradeoffs for the advantage

9 Human modification of landscapes includes extensive addition of linear features, such as roads and

10 All water bodies drain areas of extensive agriculture where phosphate-rich fertilizer is

11 the dominant beta-ladder segment of NS1 with extensive all atom molecular dynamics.

12 sure to calcitonin, proteomic analysis shows extensive alterations in extracellular matrix proteins a

13 day for 5 consecutive days, we performed an extensive analysis of topographical NREM sleep EEG respo

14 Her fundus examination and extensive ancillary testing were concerning for heredita

15 It undergoes an extensive and complex metabolism along several pathways,

16 Pancreatic cancer is characterized by an extensive and complex microenvironment, and is resistant

17 In North China, extensive and continued losses of TWS, together with sma

18 s) or 2 (D2-SPNs) in mice, we demonstrate an extensive and dynamic D2- to D1-SPN transmodulation acro

19 nd other DNA-processing enzymes are far more extensive and impressive than was thought hitherto.

20 ies of materials at the nanoscale to address extensive and inefficient resource use.

21 of conduction disorders, which are also more extensive and more severe.

22 bit ATP-dependent motor activity and promote extensive and reversible compaction of double-stranded D

23 devised novel analytical procedures enabling extensive and systematic investigation of the above issu

24 hm that integrates RNA-seq read support with extensive annotation for candidate ranking.

25 d persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-

26 The developed method finds extensive application in the routine analysis of multi-c

27 Polymeric electrospun nanofibers have extensive applications in filtration, sensing, drug deli

28 ower brain activity during working memory in extensive areas in the default mode network (i.e., great

29 nd intermetallic nanocrystals have attracted extensive attention and interest in scientific research

30 The 1,2-dicarbonyl compounds have received extensive attention due to their high reactivity and tox

31 ility to lithium metal anodes have attracted extensive attention in recent years.

32 Lithium metal anodes have attracted extensive attention owing to their high theoretical spec

33 all 500,000 participants having undergone an extensive baseline questionnaire, represents a unique op

34 l-characterized case-cohort studies that use extensive biological sampling, particularly focusing on

35 owever, dams fed the low protein diet showed extensive bone loss by the end of lactation, followed by

36 eriductular in Mdr2(-/-) mice, compared with extensive bridging fibrosis in Tr(-/-)Mdr2(-/-) mice.

37 cerebellar ataxia, extrapyramidal signs, and extensive calcifications on brain imaging.

38 ation's Pathogen Detection database revealed extensive Campylobacter species clusters carrying multip

39 only recently been detected as the result of extensive cancer genome-sequencing efforts and are linke

40 The presence of extensive centromere and telomere defects suggests a pro

41 Orchestrated events, including extensive changes in epigenetic marks, allow a somatic n

42 However, despite extensive characterization of the HSC state in the adult

43 Extensive characterization validates the robustness and

44 Furthermore, we show an extensive chemical characterization of the LnPOM species

45 cinoma is characterised by TP53 mutation and extensive chromosome instability (CIN).

46 Our analyses confirm extensive climatic overlap of forest and savanna, suppor

47 ntegrated allograft microarray analysis with extensive clinical and histologic phenotyping from 224 k

48 lescence, while divalent cations resulted in extensive coalescence.

49 malaria control programs, which can include extensive collaborations with the public sector that go

50 promoting and motor-control circuits through extensive collateral projections.

51 ative access and visualization of a uniquely extensive collection of genome-wide association study da

52 source for the maize community, providing an extensive collection of introgressions from the founders

53 genetic screening in the axolotl requires an extensive commitment of time and space.

54 This involves extensive communication between bone-forming osteoblasts

55 This work presents an extensive comparative sample of 30 extant primate specie

56 onance mass spectrometry (FT-ICR MS) enables extensive compositional characterization of the virgin a

57 The analysis of our extensive computational efforts reveals that social dist

58 S exhibits extensive conformational flexibility: it modulates expos

59 a result, analyzing scRNA-seq data requires extensive considerations of program efficiency and metho

60 domains pack more closely and have to break extensive contacts before rearrangement, corresponding t

61 Whereas the presence of extensive continental ice sheets predicts a tidally ener

62 We found extensive convergent inputs to primate reticulospinal ce

63 ressing to leukodystrophy-like features, and extensive cortical encephalitis evolving to atrophy.

64 This combination has attracted extensive coverage in media but has not been discussed i

65 Such coupling is extensive, creating an interconnected network with numer

66 Together with the extensive cross-connectivity among pharyngeal neurons, w

67 Eukaryotic gene expression relies on extensive crosstalk between transcription and RNA proces

68 The extensive crosstalk with other pathways implicated in ca

69 Extensive CT deletions and mutagenesis analyses helped u

70 Since 2017, CARD has expanded through extensive curation of reference sequences, revision of t

71 This rapid and extensive dark oxidation elevates the importance of noct

72 Using the most extensive database available on shade, drought, waterlog

73 to scan across the alloy space, and build an extensive database of segregation energy spectra for mor

74 compiling a geographically and taxonomically extensive database on plant heat and cold tolerances and

75 Extensive database searches resulted in only 13 similar

76 We used long-term demographic records and extensive databases of functional traits and distributio

77 These extensive datasets are a resource for the analysis of LA

78 rater floor, were sourced from the laterally extensive deep reservoir only.

79 This result precludes extensive deep subduction of most CO(2) and suggests tha

80 d globus pallidus of Abeta + ET1 rats showed extensive degeneration of neuronal cells compared with E

81 Autophagic vacuoles, as well as frequent and extensive deposits of lipoproteins, including immature l

82 Cs and neurons derived from ID patients have extensive deregulation of gene expression affecting path

83 enantioenriched building blocks, and further extensive developments can be expected in the future.

84 d recombinant NiV in Vero cells generated an extensive DI population from which individual DIs were i

85 unequivocally that some species that present extensive differences in chromosome organization, phenot

86 his first facial transplantation because of extensive disfigurement from type 1 neurofibromatosis an

87 Transsynaptic tracing indicates extensive disynaptic links with cognitive, affective, an

88 small subunit ribosomal RNA has revealed the extensive diversity of bacterial life on earth.

89 These populations provide extensive diversity to harness genetic, mechanistic and

90 NA replication in the next mitosis generates extensive DNA damage.

91 cillin, cotrimoxazole, and chloramphenicol), extensive drug resistance (XDR) (MDR plus non-susceptibl

92 dly settled suspended sediments to construct extensive Early Noachian highlands.

93 Our results represent the first extensive EC data-based estimates of ecosystem T permitt

94 Therefore, extensive efforts are devoted to the development of prot

95 Extensive efforts during the past decade have led to maj

96 Although extensive efforts have been dedicated to developing cata

97 impact of malaria remains staggering despite extensive efforts to eradicate the disease.

98 Despite extensive efforts, it remains insufficiently understood

99 Despite extensive efforts, we were unable to reproduce the findi

100 for single-strand annealing repair involving extensive end resection.

101 of endothelial cells with BMP-9 triggers the extensive endocytosis of ALK-1, and it is mediated by ca

102 delivered to mammalian cells all at once or extensive engineering of gene regulatory sequences can b

103 n accessibility and gene expression revealed extensive epigenetic but not transcriptional priming of

104 Analysis of transcriptomic data demonstrates extensive epigenetic gene silencing of the transcription

105 ferentiated adenocarcinoma, characterized by extensive epithelial-mesenchymal transition.

106 Overall, these studies strongly suggest that extensive erythrocyte membrane protein phosphorylation a

107 mergency Cardiovascular Care is based on the extensive evidence evaluation performed in conjunction w

108 Extensive evidence shows that DSBs are a primary source

109 There is extensive evidence that glucocorticoid hormones enhance

110 The observation of extensive evolutionary conservation in copper homeostati

111 vascular risk factors should be ruled out by extensive examination.

112 Despite extensive examples that implicate classical complement p

113 Extensive experiments showed that DeepCDR outperformed s

114 Approximately 30% of the fish displayed extensive fathering behavior within 90 min.

115 and durable strictureplasty in patients with extensive fibrostenosing CD of the small bowel.

116 cal synthesis of nucleotides, followed by an extensive focus on the prebiotic formation of the compon

117 hose without structured poles, the origin of extensive forces is less obvious.

118 The spindle must counter these forces with extensive forces to prevent spindle collapse.

119 size and system size, or, equivalently, the extensive form of generalized entropy.

120 We have developed an extensive framework for the analysis of NGS functionaliz

121 B cells from the same patient with VRL, with extensive gains and losses at the same areas across the

122 ype of autoimmune diseases, characterized by extensive gene expression perturbations in peripheral bl

123 Human NoVs exhibit extensive genetic and antigenic diversity, which makes i

124 Despite extensive genetic and neuroimaging studies, detailed cel

125 Heirloom tomatoes retain extensive genetic diversity and a considerable range of

126 Tumors harbor extensive genetic heterogeneity in the form of distinct

127 This approach revealed extensive genetic variation in predator-induced plastici

128 Both individuals were undiagnosed despite extensive genetics workups.

129 This screen utilized the most extensive genome-wide ORF collection to date, covering 9

130 to resolve due to poor tumor cellularity and extensive genomic instability.

131 echnologies are increasingly used, providing extensive genomic toolkits that were once reserved for a

132 scientific community has tackled by mounting extensive global collaborations, combining expertise in

133 While some factors have extensive global effects (eg, hypertension and education

134 Extensive glycosylation of Env is an important feature t

135 s (Danaus plexippus) is projected to require extensive habitat restoration across multiple land use s

136 -specific VEGF overexpression culminating in extensive, highly selective loss of DG GCs (thereby also

137 sted many great earthquakes, illustrating an extensive history of great earthquake seismicity that ca

138 ID-19) pandemic has spread globally, causing extensive illness and mortality.

139 IL-17 receptor-A antagonism caused extensive improvements in clinical, histologic, and tran

140 a promising novel anticancer target based on extensive in vitro and in vivo studies with archazolids,

141 Using extensive income-expenditure statistics from India, here

142 sponse or survival outcomes were observed in extensive independent validations on multiple cancer pat

143 an intermediate 5-HT-ir cell cluster, and an extensive inferior raphe population.

144 ligand to activate this pathway and trigger extensive inflammatory responses.

145 Fluorescence microscopy can provide extensive information about these changes, although it i

146 find that the scientific literature carries extensive information on the detailed chemical component

147 eveals a 1:1 stoichiometric complex with two extensive interaction interfaces between the proteins: o

148 We find that FACT is engaged in extensive interactions with nucleosomal DNA and all hist

149 f type 2 diabetes, and there is consequently extensive interest in increasing endogenous GLP-1 secret

150 cently, single atom catalysts have attracted extensive interests in electrochemical energy conversion

151 palm, and fingers subdomains of POL form an extensive interface with the primer-template and the tri

152 s of contrasting compositions, as well as an extensive internal void volume - bimodal in its size dis

153 e revealed, these input pathways reflect the extensive interplay between the clock and cell physiolog

154 xy for potential rooting depth, facilitating extensive interspecific comparison.

155 However, each such claim will require extensive investigation to justify its practical applica

156 Extensive investigations for possible causes of exudativ

157 Despite its ubiquitous use in medicine, and extensive knowledge of its molecular and cellular effect

158 slow (Wld(S)) mouse, research has generated extensive knowledge of the molecular mechanisms underlyi

159 fraction and reflectivity measurements yield extensive Laue oscillations and Kiessig thickness fringe

160 Patients with extensive LGE (>=15% of left ventricular mass) were at h

161 ystemic steroid use in the prior year and an extensive list of steroid-indicated conditions, includin

162 Given the extensive literature confirming the relationship between

163 These findings-validated against the extensive literature on GO systems in organic solvents-f

164 n some organisms, has the potential to cause extensive loss of heterozygosity, genetic disease, or ce

165 Several studies have found that a more extensive lymphadenectomy leads to better disease-specif

166 hetic membranes, and is sufficient to induce extensive membrane tubulations.

167 omain binds anionic phospholipids through an extensive membrane:protein interface.

168 asonable expectation of posttransplant cure, extensive mesenteric vein thrombosis and intestinal infa

169 Cancer cells require extensive metabolic reprograming in order to provide the

170 Extensive metabolic reprogramming occurs during tumour i

171 pivotal role in biogeochemical cycles due to extensive microbial activity.

172 Extensive migrant follow-up yielded a 92% reinterview ra

173 o its remarkable developmental potential and extensive migratory ability.

174 Here we discover extensive mixed tailing in transcripts of hepatitis B vi

175 sequencing technology greatly facilitate the extensive molecular characterization of tumors and promo

176 Extensive molecular dynamics simulations provided useful

177 We use extensive molecular dynamics simulations to determine th

178 Extensive molecular surveillance in Guangdong, China's m

179 Extensive monitoring in intensive care units (ICUs) gene

180 o-manipulation of GPR17 and microglia led to extensive myelination of regenerated axons.

181 rotein folding in the cell is mediated by an extensive network of >1,000 chaperones, quality control

182 r screen uncovered a previously undisclosed, extensive network of genes linking integrin signaling an

183 that detect DNA lesions and phosphorylate an extensive network of substrates.

184 CM significantly enhanced TGNC survival with extensive neurite outgrowth and branching as evaluated b

185 Here we detail how ZIKV infection produces extensive neuropathology in the developing mouse brain a

186 pproach (principal component analysis) on an extensive neuropsychological and aphasiological battery,

187 to principal component analysis alongside an extensive neuropsychological/aphasiological battery that

188 We have performed extensive numerical simulations on publicly available da

189 Without extensive optimization of experimental parameters, we we

190 Patients who achieved extensive or complete necrosis had better RFS, supportin

191 *However, the extensive overlap between botanical races in multivariat

192 tant angel sharks is rather restricted, with extensive overlap.

193 However, ketamine use can cause extensive pathological changes, including ketamine cysti

194 The extensive peat bogs of Southern Scandinavia have yielded

195 imensional liquid chromatography (LC/LC) for extensive peptide fractionation and high-resolution tand

196 By means of extensive performance analyses, we quantify the utility

197 tion of large-scale multi-modal imaging with extensive phenotypic and genetic data offers an unpreced

198 Here we reveal extensive phenotypic plasticity and niche complementarit

199 ns, and nearby native forests in a region of extensive plantation activity in south-central Chile.

200 ially altered expression profiles, revealing extensive plasticity of cell types and cell-type-specifi

201 clusters between mouse and human lesions and extensive plasticity of SMC- and endothelial cell-derive

202 c differences in skull organization, such as extensive postnatal fusion of cranial bones in crown bir

203 ility of the OLED to repeated bending and to extensive postprocessing, e.g. via reactive gas plasmas,

204 the widespread penetration of renewables and extensive power-sector decarbonization that previous pol

205 mains of the BET proteins that has undergone extensive pre-clinical in vitro and in vivo characteriza

206 Extensive preoperative ophthalmic evaluation and meticul

207 ion of an active water cycle on Mars and the extensive presence of perchlorate salts that depress wat

208 This expanded 50-patient cohort of men with extensive prior therapy confirms our earlier report of h

209 short median PSA doubling time (2.3 mo) and extensive prior treatment, including prior docetaxel (84

210 armful and ubiquitous aquatic pollutant with extensive production and application.

211 ing different prevention strategies in which extensive prospective high-quality data collection at ca

212 The nuclear lamina (NL) is an extensive protein network that underlies the inner nucle

213 tagenomic data rely on alignments, assembly, extensive pruning, taxonomic profiling and reference seq

214 made once they reached adulthood, along with extensive psychiatric assessment.

215 demonstrate high FFP, despite receiving less extensive radiotherapy and lower rates of additional and

216 -territorial due to their large home ranges, extensive range overlap, and limited inter-group aggress

217 ith regulome revealed the differences in the extensive re-wiring of dynamic transcriptional organizat

218 s and vascular plants is limited, suggesting extensive rearrangements since divergence.

219 taining several internal LTRs, suggestive of extensive recombination during retrotransposition.

220 nd the bullfrog's sacculus, we observed that extensive recovery of mechanoelectrical transduction, ha

221 High disease activity genomes display extensive redistribution of co-expression domains with e

222 ore conclude that polyploid hepatocytes have extensive regenerative capacity in situ and routinely un

223 oimaging results to remote participants; (4) extensive reliance on cloud-based artificial intelligenc

224 Overall, we observe extensive remodeling at active enhancers in PAH PAECs an

225 in the tumor microenvironment, leading to an extensive remodeling of the ECM and an increased infiltr

226 res at distinct cell-cycle stages, revealing extensive reorganization of kinetochores during meiosis.

227 imally rearranges even as the bulk undergoes extensive reorganization.

228 We further identified an extensive repertoire of genes involved in antibiotic res

229 ong-term treatment with gemcitabine leads to extensive reprogramming of the pancreatic tumor microenv

230 m-oxygen (Li-O(2) ) batteries have attracted extensive research interest due to their high energy den

231 Regardless of extensive research to predict, quantify, and annotate ci

232 Despite extensive research, little progress has been made in gli

233 Extensive resorption of graft particles was observed in

234 This article provides an extensive review of the available whole-grain fortificat

235 ations in the BRT model were associated with extensive riparian canopy, high levels of organic carbon

236 Recent studies have revealed an extensive role for a completely distinct layer of networ

237 xpression, and alternative splicing plays an extensive role in generating protein diversity.

238 ge state distributions tend to be narrow and extensive salt adduction, heterogeneity, and so on tend

239 vels relies on instrumentation that requires extensive sample preparation, long run times, and is des

240 This requires extensive sampling of epidemic disease over time, alongs

241 re comes with challenges, including need for extensive screening, reluctance to participate, and comp

242 emiological research in this area, including extensive selection bias, the use of noncompositionally

243 The extensive sequence changes resulting from this approach

244 Through extensive simulation studies and analysis of the HUNT st

245 aluate the performance of our measures using extensive simulation studies and publicly available data

246 Extensive simulation studies demonstrate that our propos

247 Through extensive simulation studies, the analyses of PET-imagin

248 Our extensive simulation study shows that the integrative mo

249 Extensive simulations and real data applications showed

250 lly, we validate the proposed method through extensive simulations covering both the objectives of ac

251 Extensive simulations demonstrate that the model is vali

252 of our Bayesian inference procedure through extensive simulations, showing that our approach can del

253 previous nuclear data-based methods through extensive simulations.

254 of the significance of candidate signals by extensive simulations.

255 riginal SSIS technique to address severe and extensive small bowel Crohn's disease presenting with 3

256 We undertook an extensive spectroscopic analysis of the prototypical 1 w

257 Extensive spectroscopic characterization suggests the pr

258 usion MRI quality, nondiagnostic biopsy, and extensive spinal metastasis or prior kyphoplasty.

259 Informed by both global literature and an extensive stakeholder consultation across all ecosystems

260 Transitional cells undergo extensive stretching during differentiation, making them

261 mGC(SP)), revealing that this pilin displays extensive structural conservation.

262 Extensive structural homology was found across the range

263 tion and refinement protocol, as well as the extensive structural re-assembly simulations, which allo

264 on of group A streptogramin antibiotics with extensive structural variability.

265 Extensive studies have revealed that SARS-CoV-2 shares m

266 Despite extensive studies on mesoporous silica since the early 1

267 Despite extensive studies on the association between height and

268 Despite extensive studies on the formation of organic molecules

269 However, extensive studies showed that microalgae are rich in lut

270 However, despite extensive studies, sIgA structures have remained elusive

271 This review provides an extensive summary of the effects of carbohydrate fluorin

272 e and middle-income countries, resources for extensive surgeries are scarce.

273 st patients are treated by drainage and more extensive surgery is rarely needed; in any event, in low

274 VEEV infection in vivo is characterized by extensive systemic inflammation that can exacerbate infe

275 location themselves-which typically requires extensive technical expertise-and allows them to focus o

276 still under development, social distancing, extensive testing, and quarantining of confirmed infecte

277 proteins, although this is now reinforced by extensive theoretical modeling.

278 le of maintaining large volumes of water for extensive time-periods, necessitating a precipitation-dr

279 al outcomes in OPSCC patients (n = 143) with extensive tobacco exposure (median pack-years = 40).

280 d after male rhesus macaque monkeys received extensive training to learn novel visuospatial discrimin

281 Our results demonstrate that rapid and extensive transcription reprogramming associated with he

282 pid elimination of CPSF73, which causes very extensive transcriptional readthrough genome-wide.

283 ene, phenotype, and environment will require extensive translation of data into a standard, computabl

284 Our work highlights extensive translation of lncRNAs during hESC pancreatic

285 Extensive tumour inflammation, which is reflected by hig

286 Extensive universal testing irrespective of symptoms may

287 h bacteria can be incorporated to facilitate extensive uptake by oysters.

288 , including regulation of mRNAs that require extensive uridine insertion/deletion (U-indel) editing f

289 reveal increased chromosomal translocations, extensive use of distal switch regions (consistent with

290 e MVP cohort, as well as the availability of extensive VA electronic health records, make it a promis

291 We performed an extensive validation of all deletions in the significant

292 ns of Mars are cratered landscapes, in which extensive valleys and basins are covered by ubiquitous f

293 Functional omics data reveals extensive variation in gene expression and substrate usa

294 macological CSF1R inhibitors afford the most extensive versatility in manipulating microglia, making

295 Our findings of extensive viral RNA contamination of surfaces and air ac

296 The large external pinnae and extensive vocal repertoire of the African wild dog (Lyca

297 Dark adaptation at dusk triggered extensive widening of the rhabdoms and crystalline cone

298 show the conductive ionospheric region to be extensive, with thickness of 300-800 km.

299 While extensive work has revealed the many important contribut

300 Extensive work-up and family history were unremarkable.