ライフサイエンスコーパス: extorquens

1 metabolism by the bacterium Methylobacterium extorquens.

2 species, also occurring in Methylobacterium extorquens AM1 (Me).

3 m with prepared cell mixtures (Methylorubrum extorquens AM1 and Methylomicrobium album BG8) and biosa

4 he facultative methylotroph Methylobacterium extorquens AM1 and shown to be the major regulator of th

5 ication and characterization of FtfL from M. extorquens AM1 and the confirmation that this enzyme is

6 et of strains originating from Methylorubrum extorquens AM1 are subjected to evolutionary pressures t

7 ol revealed that while cells of wild-type M. extorquens AM1 as well as cells of all the single and th

8 PA1, a strain that is closely related to M. extorquens AM1 but is lacking methylamine dehydrogenase,

9 none-containing enzyme from Methylobacterium extorquens AM1 by high resolution x-ray crystallography

10 at the analogous H(4)F pathway present in M. extorquens AM1 cannot fulfill the formaldehyde detoxific

11 ents, and (13)C-labeling experiments that M. extorquens AM1 contains an additional malyl-CoA/beta-met

12 e serine cycle methylotroph Methylobacterium extorquens AM1 contains two pterin-dependent pathways fo

13 m fumariolicum SolV and the Methylobacterium extorquens AM1 DeltamxaF mutant demonstrate that americi

14 ingle-carbon compounds-like Methylobacterium extorquens AM1 encode two routes for methylamine oxidati

15 The Methylobacterium extorquens AM1 genome contains two homologs of MxaF, Xox

16 s revealed that the protein repertoire of M. extorquens AM1 grown on acetate is similar to that of ce

17 he methylotrophic bacterium Methylobacterium extorquens AM1 involves high carbon flux through the eth

18 Methylobacterium extorquens AM1 is a facultative methylotroph capable of

19 n of common pathways during the growth of M. extorquens AM1 on C1 and C2 compounds, but with a major

20 enases is sufficient to sustain growth of M. extorquens AM1 on formate, while surprisingly, none is r

21 The methylotroph Methylobacterium extorquens AM1 oxidizes methanol and methylamine to form

22 hylotrophic proteobacterium Methylobacterium extorquens AM1 possesses tetrahydromethanopterin (H(4)MP

23 he facultative methylotroph Methylobacterium extorquens AM1 possesses two pterin-dependent pathways f

24 M. extorquens AM1 pqqE complemented a K. pneumoniae pqqF mu

25 c efficiency of wild-type (WT) Methylorubrum extorquens AM1 PqqE to a range of mutated constructs.

26 Methylobacterium extorquens AM1 pqqEF are genes required for synthesis of

27 luding PqqF of Klebsiella pneumoniae, and M. extorquens AM1 PqqF has low identity with the same endop

28 at XoxF1 (MexAM1_1740) from Methylobacterium extorquens AM1 produces formaldehyde, and not formate, d

29 nt enzyme in methylotrophic Methylobacterium extorquens AM1 prompted intensive research toward unders

30 robic alpha-proteobacterium Methylobacterium extorquens AM1 synthesizes the tetrahydromethanopterin (

31 Methylobacterium extorquens AM1 uses dedicated cofactors for one-carbon u

32 ic methylotrophic bacterium Methylobacterium extorquens AM1 was previously shown to grow using electr

33 Methylobacterium extorquens AM1 was used to explore the genetics of depho

34 l-type" genes linked on the chromosome of M. extorquens AM1 were analyzed for the ability to synthesi

35 he facultative methylotroph Methylobacterium extorquens AM1 were identified from a transposon mutagen

36 he facultative methylotroph Methylobacterium extorquens AM1 whose expression is affected by either mo

37 A mutant of Methylobacterium extorquens AM1 with lesions in genes for three formate d

38 In Methylobacterium extorquens AM1, a mutant defective in the MMAA homolog m

39 Methylobacterium extorquens AM1, a serine cycle facultative methylotroph,

40 1), C(2), and heterotrophic metabolism in M. extorquens AM1, as well as the entry metabolite for the

41 xF is not required for methanol growth in M. extorquens AM1, but here we show that when both xoxF hom

42 In Methylobacterium extorquens AM1, MaDH is essential for methylamine growth

43 In Methylobacterium extorquens AM1, the best-studied aerobic methylotroph, a

44 In Methylorubrum extorquens AM1, the periplasmic lanthanide-dependent met

45 c methylotrophic bacterium, Methylobacterium extorquens AM1, was found to contain a cluster of genes

46 model methylotrophic bacterium Methylorubrum extorquens AM1, we investigated the functional importanc

47 he facultative methylotroph Methylobacterium extorquens AM1, which lacks isocitrate lyase, the key en

48 he methylotrophic bacterium Methylobacterium extorquens AM1, while overexpression of the molecule gre

49 in replicate populations of Methylobacterium extorquens AM1.

50 C(1) and C(2) compounds in Methylobacterium extorquens AM1.

51 the absence of ccrR compared to wild-type M. extorquens AM1.

52 ch point for methylotrophic metabolism in M. extorquens AM1.

53 problem was investigated in Methylobacterium extorquens AM1.

54 he facultative methylotroph Methylobacterium extorquens AM1.

55 in the regulation of the serine cycle in M. extorquens AM1.

56 similatory C1 metabolism in Methylobacterium extorquens AM1.

57 ld-type and mutant cells of Methylobacterium extorquens AM1.

58 e oxidation and detoxification pathway in M. extorquens AM1.

59 ared to the activities found in wild-type M. extorquens AM1.

60 the key formaldehyde oxidation pathway in M. extorquens AM1.

61 le facultative methylotroph Methylobacterium extorquens AM1.

62 ved in formaldehyde oxidation to CO(2) in M. extorquens AM1.

63 e serine cycle methylotroph Methylobacterium extorquens AM1.

64 mes of three methylotrophs, Methylobacterium extorquens (an alphaproteobacterium, 7 Mbp), Methylibium

65 homolog has previously been reported for M. extorquens and assigned as the putative H2MPT reductase

66 FR from the model methylotroph Methylorubrum extorquens and identified an unusually long polyglutamat

67 dy, we have mimicked in the Methylobacterium extorquens ATR, a C-terminal truncation mutation, D180X,

68 ed from tRNA, we mutated the miaA gene of M. extorquens by single exchange of an internal miaA fragme

69 Wild-type M. extorquens cells were grown at steady state on a limitin

70 = 3) was found for CH(3)Cl degradation by M. extorquens CM4 and L. methylohalidivorans MB2, respectiv

71 here and by reference bacteria Methylorubrum extorquens CM4 and Leisingera methylohalidivorans MB2 fr

72 Methylobacterium extorquens DM4 expresses a dichloromethane dehalogenase

73 ethylotrophic bacteria such as Methylorubrum extorquens face an acute challenge due to their producti

74 cture of cytochrome cL from Methylobacterium extorquens has been determined by X-ray crystallography

75 he methylotrophic bacterium Methylobacterium extorquens have been modified by site-directed mutagenes

76 he methylotrophic bacterium Methylobacterium extorquens have indicated that an uncharacterized archae

77 l methylotrophy pathways in Methylobacterium extorquens involved in glyoxylate generation and acetyl-

78 ncoding a potential beta-RFAP synthase in M. extorquens is the first report of a putative methanopter

79 haracterize Methylobacterium (Methylorubrum) extorquens LanD, a periplasmic protein from a bacterial

80 ced by ubiquitous bacteria and Methylorubrum extorquens lanmodulin (LanM) was recently identified as

81 sent a crystal structure of Methylobacterium extorquens MeaB bound to a nonhydrolyzable guanosine tri

82 sequence similarity to the Methylobacterium extorquens MeaB, which is a chaperone for methylmalonyl-

83 In Methylorubrum extorquens, MYFR contains a large and branched polygluta

84 ndogenous formaldehyde stress response in M. extorquens PA1 and is found almost exclusively in methyl

85 Furthermore, analysis of M. extorquens PA1 mutants with defects in methylotrophy-spe

86 influences the yield during the growth of M. extorquens PA1 on methylamine.

87 In this study, we used M. extorquens PA1, a strain that is closely related to M. e

88 odel phyllosphere colonizer Methylobacterium extorquens PA1.

89 These results demonstrate that in M. extorquens, physiological heterogeneity at the single-ce

90 and meaA (62% identity) of Methylobacterium extorquens, respectively.

91 on to the prototypal LanM from Methylorubrum extorquens reveals distinct metal coordination strategie

92 t a Ln-utilizing bacterium, Methylobacterium extorquens, selectively transports early Lns (La(III)-Nd

93 ore similar to those in M. capsulatus and M. extorquens than to the ones in the more closely related

94 eobacterium Methylobacterium (Methylorubrum) extorquens that can rapidly catalyze cleavage of PqqA in

95 ylotrophic bacteria, including Methylorubrum extorquens, that are widespread in the environment.

96 Finally, we report the innate ability of M. extorquens to grow using other complex REE sources, incl

97 aize, and soybean) and of a Methylobacterium extorquens type culture originally recovered as a soil i

98 When M. extorquens was grown in the presence of tyramine, the co

99 y, the lanmodulin protein from Methylorubrum extorquens was reported, which has evolved a high affini

100 MeaB and methylmalonyl-CoA mutase from M. extorquens were cloned and purified in their active form

101 mutant of the gram-negative Methylobacterium extorquens, which introduces a link between membrane ord

102 onstrated that the ATR from Methylobacterium extorquens, which supports methylmalonyl-CoA mutase acti

103 f the strains produced MYFR as present in M. extorquens, while a modified MYFR containing tyramine in