ライフサイエンスコーパス: extracellular

1 ath by AAV-YAPdeltaC reduces the later-stage extracellular Abeta burden and cognitive impairment, sug

2 In vitro, GCBCs had a very low glycolytic extracellular acidification rate but consumed oxygen in

3 macrophage glycolytic function with enhanced extracellular acidification rate, glycolytic metabolites

4 In this study, we aimed to explore the extracellular acidity of WHO grade II and III gliomas as

5 s how tumor cells regulate intracellular and extracellular acidity while they grow in a microenvironm

6 pe II secretion system and results in higher extracellular activity for the hypervirulent AB5075 than

7 s cellular adenosine uptake, could raise the extracellular adenosine concentration and dampen chronic

8 Specifically, we demonstrate that increasing extracellular amino acids beyond the nutritional need of

9 d zones and junctional spaces-regions of the extracellular and bath or blood pool directly in contact

10 e proteins with multiple domains in both the extracellular and intracellular regions.

11 role of S1P in renal cells and how aberrant extracellular and intracellular S1P signaling contribute

12 y Ad/E2TM or naked pE2TM, both encoding HER2 extracellular and transmembrane domains.

13 technical refinements, including removal of extracellular antioxidants, to facilitate enhanced cytok

14 Extracellular ATP (eATP) is a signaling molecule that va

15 Extracellular ATP mitigates pneumolysin-induced neutroph

16 ed that DNA damage was indeed exacerbated by extracellular ATP, subsequent P2Y(2)R activation, and do

17 Before this work, an extracellular auxin receptor - rather than the auxin tra

18 ion and that a subsequent passive leakage of extracellular bacterial DNA into the host cell cytosol i

19 and molecular modeling studies suggested an extracellular binding site.

20 analyzing the evolution of intracellular and extracellular calcium fluxes during a single beat which

21 cally evoked responses require the influx of extracellular calcium through ion channels.

22 owering plants, pollen wall is a specialized extracellular cell-wall matrix surrounding male gametoph

23 ient DRMs by inducing the internalization of extracellular cholesterol and its trafficking from the P

24 he new SCNP resists uptake by cells allowing extracellular click chemistry to be performed.

25 ese processes are performed in topologically extracellular compartments or on the cell surface; hence

26 pathogenesis and for the first time identify extracellular cords in this species.

27 ot result in the significant accumulation of extracellular D-alanine.

28 of mice of either sex, while increasing the extracellular D-serine concentration in slices and in vi

29 tamine export from astrocytes would increase extracellular D-serine, providing a feedforward mechanis

30 In response to extracellular DA, both the red and green GRAB(DA) sensor

31 he overproduction of lipid- and protein-rich extracellular deposits that accumulate in the extracellu

32 ter the lipoprotein/protein profile of these extracellular deposits.

33 ell surface Cnx-ERp57 complexes reduce these extracellular disulfide bonds and are essential for ECM

34 Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to potentially immobilize them

35 involved platelets, neutrophils, fibrin, and extracellular DNA.

36 otonin) to the binding pocket located on the extracellular domain (ECD) and allosteric regulation of

37 ptides, however, little is known about their extracellular domain (ECD) conformations in the absence

38 ies that bound to a peptide representing the extracellular domain of NMDARs (p < 0.0001), however, bi

39 luble fragment generated from the N-terminal extracellular domain of PC-1 functions as an intrinsic a

40 y attaching the TGF-beta-neutralizing TGFBR2 extracellular domain to ibalizumab, a non-immunosuppress

41 actor 23 (FGF23) signaling, whereas its shed extracellular domain, soluble Klotho (sKlotho), carrying

42 ch is proteolytically cleaved to release the extracellular domain, was endocytosed by podocytes to in

43 A, a transmembrane protein with a very large extracellular domain, was found in terminal Schwann cell

44 ngstrom crystal structure of the human PD-1H extracellular domain.

45 ells and designed a peptide encompassing the extracellular domains (ECD) of PLP.

46 e present the first crystal structure of the extracellular domains of human IL-11Ralpha and a structu

47 ructures on the carbohydrate recognition and extracellular domains of the protein using sequential ex

48 ages have increased the frequency of KLRA*02 extracellular domains.

49 iphery and brain, as well as increased basal extracellular dopamine in prefrontal cortex and 5-hydrox

50 lvinar (higher-order) using optogenetics and extracellular electrophysiology in awake mice.

51 tibiotics, which often require export to the extracellular environment.

52 y of cells to sense and communicate with the extracellular environment.

53 loped virus from its site of assembly to the extracellular environment.IMPORTANCE In this report, we

54 see text] level in cells that grow in acidic extracellular environments.

55 dy, we show that lignin peroxidase (LiP), an extracellular enzyme purified from Phanerochaete chrysos

56 hydrolyzed by cell-surface attached or free extracellular enzymes (external hydrolysis) yield LMW pr

57 Matrix metalloproteinases (MMPs) are extracellular enzymes involved in the degradation of ext

58 Extracellular enzymes, lignin degradation and cell growt

59 th cell adhesion, inflammatory response, and extracellular exosome.

60 ith a more open receptor conformation at the extracellular face.

61 dis biofilm formation, and we confirmed that extracellular fibrils from these biofilms contain Aap.

62 We quantified total (unfiltered) and extracellular (filtered at < 0.22 um) TLF and HLF in 140

63 Increased extracellular fluid leads to elevated intracardiac filli

64 d 12 months in interdialytic weight gain, in extracellular fluid volume, and in plasma B-type natriur

65 ent in roots, yet we also find cytokinins in extracellular fluid, potentially enabling action at the

66 terns in an environment imitating biological extracellular fluids.

67 tilizing trypan blue, Southern blotting, and extracellular flux analysis, respectively.

68 Although extracellular force has a profound effect on cell shape,

69 network activity trigger widespread waves of extracellular GABA in hippocampal neuropil.

70 s, indicating a defect linked with decreased extracellular glutamate availability.

71 ipulations that increase the availability of extracellular glutamate during neural activity can have

72 effect was partly mitigated by replenishing extracellular glutamate levels, indicating a defect link

73 n land plants are covered by the cuticle, an extracellular hydrophobic layer that provides protection

74 Specifically, the 3 mutations located within extracellular (ie, NTRK2A203T and NTRK3E176D) and transm

75 ells express IL-17A receptors and respond to extracellular IL-17A by inducing proinflammatory cytokin

76 lar environmental stability at pH 7.0; thus, extracellular inactivation was unlikely to attenuate the

77 subset of CD4(+) T cells, help to eliminate extracellular infectious pathogens that have invaded our

78 nce recruited into the membrane it increased extracellular inorganic pyrophosphate, mineralization, a

79 iptomics data and can propose novel pairs of extracellular interacting genes.

80 with the 35-residue N-terminal region of its extracellular interaction partner CsgF to produce a dual

81 The effects of altering extracellular ionic concentrations on immune responses a

82 ctive electron transport chain decreased the extracellular lactate:pyruvate ratio, normalized the int

83 they extend core lipopolysaccharides in the extracellular leaflet of the outer membrane.

84 The P2K2 extracellular lectin domain binds to ATP with higher aff

85 efflux agonist did not inhibit the uptake of extracellular leucine but instead facilitated the efflux

86 the activity of dopamine-releasing neurons, extracellular levels of dopamine and net PKA activity in

87 ses via alternative splicing and retains the extracellular ligand binding domain but lacks the intrac

88 The function of free ISG15 as an extracellular ligand was demonstrated, because the equiv

89 al questions raised by the presence of large extracellular ligand-binding domains (LBDs) and constitu

90 n or flipping of the beta11-12 linker in the extracellular, ligand-binding domain is an integral comp

91 ess is driven by a decreased availability of extracellular lipids.

92 and a negatively charged aspartate (D112) in extracellular loop 1 that helps determine Orai1 turnover

93 ction between positively charged arginine in extracellular loop 2 (K210) and a negatively charged asp

94 phobic pocket at the interface of the second extracellular loop and fifth transmembrane segment of th

95 opulation causes an R154Q substitution in an extracellular loop of SLC44A2 that is protective against

96 uctural and functional study establishes the extracellular loops as important structural motifs for i

97 3)AR affinity by polar interactions with the extracellular loops, predicted using docking and molecul

98 chRCC cells depended on extracellular macromolecules as an amino acid source by

99 pothesise, however, that it is predominantly extracellular material that fluoresces at these waveleng

100 s are molded and protected in part by apical extracellular matrices (aECMs) that line their lumens.

101 spatial-temporal relationship between cells, extracellular matrices, and mineral deposits is fundamen

102 xtracellular deposits that accumulate in the extracellular matrix (Bruch's membrane (BrM)) adjacent t

103 ganization is mediated by cell-cell and cell-extracellular matrix (ECM) adhesions and is modulated by

104 Both the extracellular matrix (ECM) and DNA epigenetic regulation

105 IL-33 instructs microglial engulfment of the extracellular matrix (ECM) and that its loss leads to im

106 rrying mutations affecting links between the extracellular matrix (ECM) and the TRNs but could not de

107 uroinflammatory signaling and non-permissive extracellular matrix (ECM) components.

108 e composition and physical properties of the extracellular matrix (ECM) critically influence tumor pr

109 x metalloproteinases (MMPs), that are key in extracellular matrix (ECM) degradation.

110 mor-stroma co-cultures consisting of aligned extracellular matrix (ECM) fibers and ordered micro-arch

111 ng process, eCRT induces abundant neo-dermal extracellular matrix (ECM) formation by 3 days post-woun

112 The extracellular matrix (ECM) is a complex and dynamic mesh

113 gned to the complement, lipid metabolism, or extracellular matrix (ECM) pathways and ARMS2 also were

114 lular enzymes involved in the degradation of extracellular matrix (ECM) proteins.

115 Extracellular matrix (ECM) remodeling is a hallmark of t

116 n fibrillar elastin and collagens leading to extracellular matrix (ECM) stabilization.

117 objective of this study is to elucidate the extracellular matrix (ECM) structure, composition, and b

118 properties and indications of scaffold-based extracellular matrix (ECM) technologies as alternatives

119 ting cells move across diverse assemblies of extracellular matrix (ECM) that can be separated by micr

120 uantitative mass spectrometry to analyze the extracellular matrix (ECM), a critical component of meta

121 iveness to environment, including changes in extracellular matrix (ECM), is critical for normal proce

122 The delivery of stem cells on an extracellular matrix (ECM)-based platform alters cell be

123 istances, which requires EVs to traverse the extracellular matrix (ECM).

124 and glycoprotein phases of connective tissue extracellular matrix (ECM).

125 ing growth factor-beta and the deposition of extracellular matrix - have metabolic implications.

126 ing mechanisms used by the cell to sense its extracellular matrix also play a role in intercellular i

127 l tethering to the surrounding cytoskeleton, extracellular matrix and cells, and tissue-level archite

128 In addition to producing the extracellular matrix and joint lubricants, FLS in RA pro

129 ive disease, characterized by alterations in extracellular matrix and loss of smooth muscle cells (SM

130 ocal adhesions linking signaling between the extracellular matrix and the actin cytoskeleton.

131 es and signal molecules, plant cells use the extracellular matrix as an alternative route for cell-ce

132 of proteins associated with inflammation and extracellular matrix as well as senescence-associated se

133 ene expression profile, referred to as ECM3 (Extracellular Matrix Cluster 3), indicated poorer surviv

134 ientation of reinforcing fibers representing extracellular matrix collagen.

135 pted by heparin, used as a surrogate for the extracellular matrix component, heparan sulfate.

136 a broad spectrum of substrates ranging from extracellular matrix components and adhesion molecules t

137 , imaging analysis show that CXCL13 binds to extracellular matrix components in situ, constraining it

138 the effects of age on PV leaflet thickness, extracellular matrix components, and mechanical properti

139 is characterized by exuberant deposition of extracellular matrix components, leading to the deterior

140 phocytes and associated cytokines; decreased extracellular matrix components; and reductions in marke

141 How extracellular matrix contributes to tissue morphogenesis

142 re the major cellular contributors to excess extracellular matrix deposition in the diseased liver an

143 Here, we sought to determine how the extracellular matrix directs synapse formation and regul

144 The extracellular matrix encompasses a reservoir of bioactiv

145 cible factor-mediated adaptation to hypoxia, extracellular matrix formation, epigenetic regulation of

146 essive H3K9me3 and H3K27me3 histone marks on extracellular matrix gene promoters and active H3K4me3 m

147 lent transcriptional changes particularly in extracellular matrix genes, and this was accompanied by

148 ein linkage between the cytoskeleton and the extracellular matrix in skeletal muscle may contribute t

149 Extracellular matrix in solid tumors has emerged as a sp

150 a prominent role in cell-matrix adhesion via extracellular matrix molecule fibronectin-induced alpha5

151 pathogens, such as mammalian reovirus, mimic extracellular matrix motifs to specifically interact wit

152 ous neuron-specific substructures within the extracellular matrix of the central nervous system that

153 taneous wound healing with discussion on how extracellular matrix proteins and hypoxia can be utilize

154 ion of inert heat-derived HSA hydrogels with extracellular matrix proteins and these may be used as a

155 ive synthesis, deposition and remodelling of extracellular matrix proteins in fibrosis.

156 sm, unfolded protein responses, secretion of extracellular matrix proteins, and cell proliferation.

157 MV receptor integrin beta 1 dissociates from extracellular matrix proteins, becoming internalized wit

158 e severity of pulmonary fibrotic lesions and extracellular matrix remodeling, and improved pulmonary

159 th smooth muscle cells (SMCs), inflammation, extracellular matrix remodeling, and mitogens.

160 moting inflammation by driving angiogenesis, extracellular matrix remodelling, metastasis and immunos

161 Further characterization of the extracellular matrix showed strong aggrecan and collagen

162 ts that most enriched proteins play roles in extracellular matrix structure and remodeling.

163 lated to methylation, protein glycosylation, extracellular matrix structure, sugars, Krebs cycle inte

164 and its binding proteins to form bridges of extracellular matrix that ligate the severed ends of the

165 lex targeting materials that penetrate brain extracellular matrix to increase transfection efficiency

166 in transmitting mechanical stimuli from the extracellular matrix to tendon cells, thereby triggering

167 ability of spheroid cancer cells deprived of extracellular matrix to undergo ferroptosis.

168 Cell-ECM (extracellular matrix) interactions play essential roles

169 ury leads to podocyte loss or an increase of extracellular matrix, altering glomerular cellular compo

170 ion complexes link the glial membrane to the extracellular matrix, but little is known about integrin

171 s: metabolism, signaling, electrophysiology, extracellular matrix, clotting, and inflammation.

172 ons are surrounded by specializations of the extracellular matrix, the perineuronal nets (PNNs).

173 Fibrosis is the abnormal deposition of extracellular matrix, which can lead to organ dysfunctio

174 in pathways linked to insulin secretion and extracellular matrix-receptor interaction.

175 cell migration, with increased expression of extracellular matrix-related genes, including MMP7 and M

176 lly burst, releasing their contents into the extracellular matrix.

177 growth, migration, and the formation of the extracellular matrix.

178 functionally distinct layers, cell types and extracellular matrix.

179 nt astroglial processes and the perisynaptic extracellular matrix.

180 e process by which cells follow gradients of extracellular mechanical stiffness, has been proposed as

181 release adenosine triphosphate (ATP) to the extracellular medium, which can be hydrolyzed to adenosi

182 This platform, designed to mimic the tight extracellular migration tracts in brain parenchyma, allo

183 intracellular vesicles, organelles, and the extracellular milieu in eukaryotes.

184 Whether more iron in the extracellular milieu of the lung associates with distinc

185 obin/CC-10); between groups of DS and NS for extracellular newly identified RAGE binding protein and

186 ry processes, primarily through detection of extracellular nucleotides that are released by dying or

187 Pseudomonas aeruginosa is an extracellular opportunistic bacterial pathogen commonly

188 Removal of either extracellular or intra-pipette Na(+) had no effect on th

189 ecrete IL-17A and are important for clearing extracellular pathogens, but inappropriate signaling has

190 xplored the importance of different forms of extracellular PDL1, such as on exosomes or as a freely s

191 er, little is known about the specificity of extracellular peptidases derived from wastewater microbi

192 crotubule-associated protein tau (p-tau) and extracellular plaques primarily comprising amyloid- beta

193 Mechanical pressure of hyphae and extracellular polymeric substances was investigated for

194 olecules, with formation being influenced by extracellular polymeric substances.

195 rization of the LEC secretome identified the extracellular protein reelin (RELN) as a key component o

196 esolution that the most abundantly expressed extracellular protein, human serum albumin (HSA), inhibi

197 The lysyl oxidase (LOX) family of extracellular proteins plays a vital role in catalyzing

198 ne module is responsible for translating the extracellular proteins required for growing, repairing o

199 II secretion systems secrete a wide range of extracellular proteins that play important roles in bact

200 er certain conditions it is possible for non-extracellular proteins to have superior outflux relative

201 roteins to have superior outflux relative to extracellular proteins.

202 Extracellular purines, adenosine and ATP, protected agai

203 The combination of in vivo extracellular recording and genetic-engineering-assisted

204 These data include paired intracellular/extracellular recordings and state-of-the-art simulated

205 Furthermore, dense extracellular recordings from awake mice reveal changes

206 Extracellular recordings from mice exploring real 2D are

207 In this study, we performed extracellular recordings in adult female mice to monitor

208 activates in a traveling wave, we performed extracellular recordings of local field potentials (LFP)

209 Moreover, extracellular recordings show that the digestion of PNNs

210 nS(SC), and traced these interactions to the extracellular region of the protein, which we reveal ado

211 The domain structure of RPTPs comprises an extracellular region, a transmembrane helix, and two tan

212 transactivation of NF-kappaB to promote the extracellular release of pro-inflammatory mediators.

213 ed that chromatographic fractions containing extracellular ribosomes are probably not silent from an

214 amount of attention, the biogenesis of these extracellular RNA fragments remains largely unexplored.

215 Extracellular RNAs participate in intercellular communic

216 I(Kv1.5) Our results further showed that the extracellular S1-S2 linker of Kv1.5 communicates with th

217 ture than the Pro to Gln substitution in the extracellular segment of S6.

218 nus has long-range allosteric effects on the extracellular segments of the receptor that may contribu

219 When extracellular serine is limited, EpdSCs activate de novo

220 s demonstrates that the IUTD enters from the extracellular side of OmpF and translocates to the perip

221 0) value, suggesting that MDIMP binds to the extracellular side of the pore.

222 s report a fascinating phenotype whereby the extracellular signal-regulated kinase (ERK) pathway regu

223 e required for host immune response, whereas extracellular signal-regulated kinase (ERK), which is es

224 rotein kinase (MAPK) signaling, encompassing extracellular signal-regulated kinase 1/2 (ERK1/2), p38

225 to a series of downstream events, including extracellular signal-regulated kinase 1/2 and c-Jun N-te

226 ading to activation of MAPK kinase (MEK) and extracellular signal-regulated kinase 1/2 signaling; how

227 to enhance the efficacy of BRAF-MAPK kinase-extracellular signal-regulated kinase pathway inhibition

228 g family, pyrin domain-containing-3, and p38/extracellular signal-regulated kinase signaling pathways

229 s and Pam3Cys led to phosphorylation of ERK (extracellular signal-regulated kinase), JNK, and p38 mit

230 he mitogen-activated protein kinase 1 (i.e., extracellular signal-regulated protein kinase 2, ERK2),

231 r of mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinase (ERK) (MEK) 1/2, w

232 This capacity depends on the integration of extracellular signaling through multiple receptors, incl

233 ious, relevant human platform to investigate extracellular signals for cardiac muscle survival, subst

234 excitatory synapse generated large negative extracellular signals that nonsynaptically inhibited nei

235 dients, morphogens drive graded responses to extracellular signals, thereby fine-tuning cell behavior

236 ysiology across human tissues in response to extracellular signals.

237 pic presence of both macrophage types in the extracellular site surrounding the outer aspect ofphotor

238 orting cells that dramatically increased the extracellular space and speed of K(+) redistribution.

239 In the extracellular space between photoreceptors, Muller glial

240 ventually rupture, releasing material to the extracellular space prior to catastrophic axon degenerat

241 umulation in AD, tau is also released in the extracellular space, as revealed by its increased presen

242 distinct Y RNA fragments are abundant in the extracellular space, including in biofluids.

243 y alter the concentrations of solutes in the extracellular space.

244 hannel GOF isolated heart model and modulate extracellular spaces via osmotic agents.

245 potentials, inferring synaptic effects from extracellular spiking is challenging.

246 Moreover, extracellular SQSTM1 binds to insulin receptor, which in

247 interferon-mediated signaling in response to extracellular stimuli and pathogen infections.

248 types can display variable responsiveness to extracellular stimuli, although little is known about th

249 ent apoptosis, or necroptosis in response to extracellular stimuli.

250 ey signaling components upon reception of an extracellular stimulus.

251 aggrecan and brevican, markers of mesh-like extracellular structures known as perineuronal nets whos

252 he cytoskeleton and their transmission to an extracellular substrate through specific adhesion molecu

253 ther demonstrate that this total marine dark extracellular superoxide flux is consistent with concent

254 patients compared with controls, whereas the extracellular survivin CD4(+) percentage was unaffected.

255 s in nanodomain geometries representative of extracellular synapses, within which we localize the nuc

256 psA-Psr (LCP) enzyme family, offers a unique extracellular target for the development of new anti-inf

257 The cerebrospinal fluid (CSF) contains an extracellular thread conserved in vertebrates, the Reiss

258 the bound substrate is translocated from the extracellular to the cytoplasmic side of the membrane, i

259 We previously showed that anti-neutrophil extracellular trap (NET) rheumatoid arthritis (RA)-rmAbs

260 led to a significant reduction in neutrophil extracellular trap formation, reactive oxygen species pr

261 inflammation through discharge of neutrophil extracellular traps (NETs).

262 rom cancer patients extrude their neutrophil extracellular traps (NETs).

263 of release of histones and DNA as neutrophil extracellular traps (NETs).

264 S aureus was captured by extracellular traps and entered mast cells through phago

265 Neutrophil extracellular traps cell death in CRSwNP was associated

266 ophils were less prone to undergo neutrophil extracellular traps cell death in the tissue of patients

267 demonstrate the importance of neutrophil extracellular traps in helminth damage after primary inf

268 sibly dissociates to fluoresce in the acidic extracellular tumor microenvironment due to the mechanis

269 Extracellular unit activity was measured with 64-channel

270 production and exchange of various types of extracellular vesicle (EV).

271 Extracellular vesicle maturation was also defective in t

272 Neurally derived extracellular vesicle protein abnormalities also reveal

273 in the vascular lumen and that inhibition of extracellular vesicle release blocks LTB4-mediated autoc

274 Its presence in extracellular vesicles (EV) has been postulated to be im

275 Recently, increasing evidence has shown that extracellular vesicles (EV) released by NK cells carry p

276 The mechanical properties of extracellular vesicles (EVs) are known to influence thei

277 Extracellular vesicles (EVs) are membrane vesicles secre

278 Extracellular vesicles (EVs) form an endogenous transpor

279 We found that extracellular vesicles (EVs) from young astrocyte were s

280 We investigated the applications of extracellular vesicles (EVs) isolated from probiotic Lac

281 Extracellular vesicles (EVs) represent an important meth

282 Cells release extracellular vesicles (EVs) to communicate over long di

283 g Fasciola hepatica, are active secretors of extracellular vesicles (EVs), but research has not been

284 vestigated how HIV-1 protein Nef secreted in extracellular vesicles (exNef) impairs neuronal function

285 er cells maintained in hypoxia release small extracellular vesicles (sEVs) that activate mitochondria

286 Pancreatic tumor cells release small extracellular vesicles (sEVs, exosomes) that contain lip

287 indings show that chemotherapy-induced small extracellular vesicles accelerate breast cancer metastas

288 etome including glycoproteins, microRNAs and extracellular vesicles as potential biomarkers of diseas

289 Serum extracellular vesicles from 74 individuals presumed to h

290 t detected M. tuberculosis peptides in serum extracellular vesicles from TB patients.

291 Notably, we also found that neutrophils shed extracellular vesicles in the vascular lumen and that in

292 Plasmatic exosomes are extracellular vesicles involved in the intercellular com

293 in through the release of ADAM10 on exosomes-extracellular vesicles of endosomal origin.

294 ular communication, involving gap junctions, extracellular vesicles, and tunneling nanotubes, some of

295 Extracellular vesicles, including exosomes/microvesicles

296 T-2262, a Na(V)1.7 inhibitor that blocks the extracellular vestibule of the channel with an IC(50) of

297 Extracellular virions are required for cell-to-cell spre

298 UC, 0.97 vs 0.90, respectively; P = .03) and extracellular volume (AUC, 0.97 vs 0.88, respectively; P

299 en) exhibited increased myocardial fibrosis (extracellular volume fraction, 0.34 +/- 0.06 vs 0.29 +/-

300 ides to explore the specificity of dissolved extracellular wastewater peptidases.