ライフサイエンスコーパス: extracellular signal

1 g transcription factors (STFs) responsive to extracellular signals.

2 ial for normal cellular responses to diverse extracellular signals.

3 which react 'on demand' to intracellular and extracellular signals.

4 les responsible for receiving and processing extracellular signals.

5 mework that is responsive to a wide range of extracellular signals.

6 onserved process that responds to intra- and extracellular signals.

7 ysiology across human tissues in response to extracellular signals.

8 e and mediated through intracellular but not extracellular signals.

9 investigation of POLGARF suggests a role in extracellular signaling.

10 Protein-Coupled Receptors (GPCRs) transduce extracellular signals and activate intracellular pathway

11 llular organelles that receive and transduce extracellular signals and whose dysfunctions lead to rar

12 ube growth through the pistil in response to extracellular signals, and regulate the actin cytoskelet

13 During development, extracellular signals are integrated by cells to induce

14 ement with substratum is more important than extracellular signals at regulating Scar/WAVE's activity

15 Cue-induced t-SP depends on extracellular signaling by matrix metalloproteases (MMPs

16 y and lack of direct contributory effects of extracellular signaling by vIL-6 or hIL-6.

17 Transcriptional networks, regulated by extracellular signals, control cell fate decisions and d

18 In most cases, the extracellular signals controlling tuft cell effector fun

19 pports long-term cell viability, response to extracellular signaling cues and ability to produce solu

20 Also discussed are extracellular signaling effects of NAD(+) mediated by AD

21 ing relative rather than absolute changes in extracellular signals enables cells to make decisions in

22 e (NAD(+)) participates in intracellular and extracellular signaling events unrelated to metabolism.

23 ious, relevant human platform to investigate extracellular signals for cardiac muscle survival, subst

24 The major sperm protein domain (MSPd) has an extracellular signaling function implicated in amyotroph

25 ce and an evolutionarily ancient, ubiquitous extracellular signal in diverse species.

26 The need for extracellular signalling in plasmodesmata-networked tiss

27 ve demonstrated that precise combinations of extracellular signals induce distinct ectodermal cell po

28 ganelle that is responsible for transmitting extracellular signals into a cell.

29 ptors (GPCRs) are essential for transferring extracellular signals into carefully choreographed intra

30 mbrane alpha-helical structure, transmitting extracellular signals into cells to regulate major physi

31 cilia act as communication hubs to transfer extracellular signals into intracellular responses and a

32 F-kappaB) pathway, which integrates multiple extracellular signals into transcriptional programs for

33 MP is exported by cancer cells and that this extracellular signal is an immunotransmitter key to tumo

34 y of newly synthesized GPCRs is regulated by extracellular signals is less understood.

35 P2RX7 and adenosine via A(2A) R are survival extracellular signals key for retina regeneration in zeb

36 Our findings reveal an extracellular signaling mechanism whereby a cell-surface

37 Adenosine, a key extracellular signaling mediator, regulates several aspe

38 acid (LPA) is a phospholipid that acts as an extracellular signaling molecule and activates the famil

39 Trunk, an ancient extracellular signalling molecule and a well-established

40 n-coupled receptors (GPCRs) typically detect extracellular signal molecules on the cell surface and t

41 Axon guidance requires interactions between extracellular signaling molecules and transmembrane rece

42 hereby bacteria produce, release, and detect extracellular signaling molecules called autoinducers to

43 eproductive tissues, which are controlled by extracellular signaling molecules interacting with recep

44 indicated that AGR2 directly binds to these extracellular signaling molecules, and enhances their ho

45 on the production, detection and response to extracellular signalling molecules called autoinducers.

46 ate degradation product adenosine are potent extracellular signalling molecules that elicit a variety

47 Cell division is often regulated by extracellular signaling networks to ensure correct patte

48 The effects of soluble extracellular signals on these cellular functions are fa

49 The extracellular signals, particularly neuron-derived molec

50 Our work identifies an extracellular signaling pathway regulating formative roo

51 of regulation of DOR export and delivery by extracellular signaling pathways.

52 insic transcriptional programs interact with extracellular signals present in the environment of MGE

53 Subsequently, self-generated extracellular signals provide morphological cues that re

54 ed protein kinase C (PKC) in the cytosol and extracellular signal regulated kinase (ERK) in the cytos

55 Here we address this question for extracellular signal regulated kinase (Erk) signaling, a

56 actor (FGF) proteins that signal through the extracellular signal regulated kinase (ERK)/mitogen acti

57 reased phosphorylation level of both Src and extracellular signal regulated kinase proteins and with

58 cardiovascular disease, is known to activate extracellular signal regulated kinases 1 and 2 (ERK1/2).

59 induce specific responses through a common, extracellular-signal regulated kinase (ERK)-dependent ca

60 beta-arrestin recruitment and DHA-dependent extracellular-signal regulated kinase-1/2 (ERK1/2) signa

61 d subsequent beta-arrestin-2 recruitment and extracellular-signal regulated kinase-1/2 activity.

62 Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activati

63 y slightly reduced downstream phosphorylated extracellular signal-regulated kinase (ERK) (pERK) level

64 acid dibutylester and imiquimod showed that extracellular signal-regulated kinase (ERK) 1/2 cascade

65 APK target gene expression and assessment of extracellular signal-regulated kinase (ERK) 1/2 phosphor

66 R1 by RO5166017 increased phosphorylation of extracellular signal-regulated kinase (ERK) 1/2, and pro

67 hrough the posttranscriptional activation of extracellular signal-regulated kinase (ERK) 5 signaling,

68 ly localized D2R long isoform (D2LR) elicits extracellular signal-regulated kinase (ERK) activation a

69 ositide 3-kinase (PI3Kgamma) plays a role in extracellular signal-regulated kinase (ERK) activation f

70 ies have suggested that dysregulation in RAS-extracellular signal-regulated kinase (ERK) activation i

71 Aberrant extracellular signal-regulated kinase (ERK) activation v

72 duced two mechanistically distinct phases of extracellular signal-regulated kinase (ERK) activation,

73 Although deregulation of MEK/extracellular signal-regulated kinase (ERK) activity is

74 l cell clusters display waves of oscillatory extracellular signal-regulated kinase (ERK) activity, wh

75 iated with a sustained increase in cytosolic extracellular signal-regulated kinase (ERK) activity.

76 o mitogen-activated protein kinases (MAPKs), extracellular signal-regulated kinase (ERK) and c-Jun N-

77 3T cell line and assessing activation of the extracellular signal-regulated kinase (ERK) and JUN N-te

78 e potent in inhibition of phosphorylation of extracellular signal-regulated kinase (ERK) and of cell

79 Extracellular signal-regulated kinase (ERK) and protein

80 xin-1 deficient B cells to the activation of extracellular signal-regulated kinase (ERK) and signal t

81 rosarcoma cells naturally expressing mutated extracellular signal-regulated kinase (ERK) antigen, the

82 DNA damage-mediated activation of extracellular signal-regulated kinase (ERK) can regulate

83 lu5-scaffolding protein Homer2 and activated extracellular signal-regulated kinase (ERK) in an adapti

84 es cell proliferation and phosphorylation of extracellular signal-regulated kinase (ERK) in NF1 (-/-)

85 es cell proliferation and phosphorylation of extracellular signal-regulated kinase (ERK) in NF1(-/-)

86 by combined treatment with rapamycin and an extracellular signal-regulated kinase (ERK) inhibitor.

87 Preclinical studies suggest that extracellular signal-regulated kinase (ERK) inhibitors a

88 D8931, identified multiple components of the extracellular signal-regulated kinase (ERK) mitogen-acti

89 The extracellular signal-regulated kinase (ERK) pathway is a

90 s report a fascinating phenotype whereby the extracellular signal-regulated kinase (ERK) pathway regu

91 and potently inhibited the pro-proliferative extracellular signal-regulated kinase (ERK) pathway; to

92 lic, vascular endothelial growth factor, and extracellular signal-regulated kinase (ERK) pathways are

93 omal signaling by protein kinase C (PKC) and extracellular signal-regulated kinase (ERK) pathways med

94 f the mitogen-activated protein (MAP) kinase extracellular signal-regulated kinase (ERK) prevents ste

95 sponsive and oncogenically activated protein extracellular signal-regulated kinase (ERK) promotes mot

96 Appropriate activation of the Ras/extracellular signal-regulated kinase (ERK) protein sign

97 ow that miR-431 overexpression activates Ras/extracellular signal-regulated kinase (Erk) signaling an

98 d by Jun N-terminal protein kinase (JNK) and extracellular signal-regulated kinase (ERK) signaling at

99 protein 2 (SREBP2) through activation of the extracellular signal-regulated kinase (ERK) signaling pa

100 es via the c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) signaling pa

101 ventral tegmental area via modulation of the extracellular signal-regulated kinase (ERK) signaling pa

102 and mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) signaling pa

103 tations in the genes involved in the RAF/MEK/extracellular signal-regulated kinase (ERK) signaling pa

104 uced endocytosis is associated with impaired extracellular signal-regulated kinase (ERK) signaling, d

105 11-kDa and Grb2 interaction disrupts extracellular signal-regulated kinase (ERK) signaling, w

106 activation by GPCRs and CAMs, giving rise to extracellular signal-regulated kinase (ERK) signaling.

107 Fibroblast growth factor (FGF)-extracellular signal-regulated kinase (ERK) signalling i

108 disruption of the transcriptional control of extracellular signal-regulated kinase (ERK) signalling.

109 Here, we adapt the first-generation KTR for extracellular signal-regulated kinase (ERK) to allow eas

110 of NF-kappaB, c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and Akt (oc

111 bated with inhibitors of MEK (trametinib) or extracellular signal-regulated kinase (ERK), and some ce

112 ased mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK), mTOR, and p

113 gnalling pathways such as those regulated by extracellular signal-regulated kinase (ERK), protein kin

114 ing leukocyte protein of 76 kDa (SLP76), and extracellular signal-regulated kinase (Erk), were enhanc

115 e required for host immune response, whereas extracellular signal-regulated kinase (ERK), which is es

116 we investigated the DA D1 receptor (D1R) and extracellular signal-regulated kinase (ERK)-cAMP-respons

117 amide, KGF-pretreated mice also had apparent extracellular signal-regulated kinase (ERK)-driven proli

118 AF binding potential, and therefore altering extracellular signal-regulated kinase (ERK)-mediated PKM

119 ndritic cells (DCs) is triggered by IL-6 and extracellular signal-regulated kinase (ERK)-mitogen-acti

120 ciated herpesvirus (KSHV) requires sustained extracellular signal-regulated kinase (ERK)-p90 ribosoma

121 (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Kinase (ERK)-signaling ca

122 3 phosphorylation on sites phosphorylated by extracellular signal-regulated kinase (ERK).

123 a to significantly reduce phosphorylation of extracellular signal-regulated kinase (ERK).

124 integrin-mediated phosphorylation of Src and extracellular signal-regulated kinase (ERK).

125 es apoptosis through increased activation of extracellular signal-regulated kinase (ERK).

126 rylation of downstream MAPK/ERK kinase (MEK)/extracellular signal-regulated kinase (ERK).

127 ownregulating the phosphorylation of MEK and extracellular signal-regulated kinase (ERK).

128 , p21-activated protein kinases (PAK1/2) and extracellular signal-regulated kinase (ERK)/C-Jun N-term

129 of epidermal growth factor receptor (EGFR), extracellular signal-regulated kinase (ERK)1/2 or a TFF2

130 ses, mitogen-activated protein kinase [i.e., extracellular signal-regulated kinase (ERK)], and p70S6

131 Fibroblast growth factor-extracellular signal-regulated kinase (FGF -ERK) signall

132 vation of a mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) negativ

133 ppaB kinase (IKK), mitogen-activated protein extracellular signal-regulated kinase (MEK), and Jun N-t

134 the neuronal activity marker phosphorylated extracellular signal-regulated kinase (pERK) identified

135 ibrosarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (Raf/MEK/ERK) path

136 phorylation switch of IRS1/2 orchestrated by extracellular signal-regulated kinase 1 and 2 (ERK1/2) a

137 sults in the nuclear translocation of active extracellular signal-regulated kinase 1 and 2 (ERK1/2),

138 f BRAF/NRAS mutations and hyperactivation of extracellular signal-regulated kinase 1 and 2 (ERK1/2),

139 in treatment and INSM1 inhibition suppressed extracellular signal-regulated kinase 1/2 (ERK1/2) activ

140 ct resulted from cell-specific regulation of extracellular signal-regulated kinase 1/2 (ERK1/2) activ

141 Recent work suggested that the activity of extracellular signal-regulated kinase 1/2 (ERK1/2) is in

142 pathways, including the NF-kappaB, AKT, and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw

143 N-gamma, and the JAK1, STAT1, NF-kappaB, and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw

144 inositol monophosphate (IP(1)) accumulation, extracellular signal-regulated kinase 1/2 (ERK1/2) phosp

145 U50,488H-induced activation of extracellular signal-regulated kinase 1/2 (ERK1/2) was G

146 e (PI3-K), protein kinase C-zeta (PKC-zeta), extracellular signal-regulated kinase 1/2 (ERK1/2), NF-k

147 rotein kinase (MAPK) signaling, encompassing extracellular signal-regulated kinase 1/2 (ERK1/2), p38

148 iptolide binds to and activates p38alpha and extracellular signal-regulated kinase 1/2 (ERK1/2), whic

149 asmin generation, but instead is mediated by extracellular signal-regulated kinase 1/2 (ERK1/2)-regul

150 R321 inhibits only the early phase of extracellular signal-regulated kinase 1/2 activation and

151 f both intracellular Ca(2+) mobilization and extracellular signal-regulated kinase 1/2 activation, wh

152 C cells and resulted in potent inhibition of extracellular signal-regulated kinase 1/2 activation.

153 A cell lines in a dose-dependent manner, and extracellular signal-regulated kinase 1/2 and AKT.

154 to a series of downstream events, including extracellular signal-regulated kinase 1/2 and c-Jun N-te

155 hosphates) in some signaling events, such as extracellular signal-regulated kinase 1/2 and label free

156 cted with the LRP1/NMDA-R system to activate extracellular signal-regulated kinase 1/2 and promote ce

157 and was coupled with decreased expression of extracellular signal-regulated kinase 1/2 kinase signali

158 pling, betaarr recruitment, endocytosis, and extracellular signal-regulated kinase 1/2 mitogen-activa

159 assays, and ChIP revealed that DDR2 acts via extracellular signal-regulated kinase 1/2 mitogen-activa

160 that Ach upregulated TGFbetaRII through Src-extracellular signal-regulated kinase 1/2 pathway to pot

161 i) coupling as measured by cAMP response and extracellular signal-regulated kinase 1/2 phosphorylatio

162 urally distinct MEKi trametinib and elevated extracellular signal-regulated kinase 1/2 phosphorylatio

163 ray of mechanistic studies revealed impaired extracellular signal-regulated kinase 1/2 signaling in H

164 n-1-SYK-epidermal growth factor receptor-AKT/extracellular signal-regulated kinase 1/2 signaling path

165 n high glucose condition interferes with Src-extracellular signal-regulated kinase 1/2 signaling, res

166 ading to activation of MAPK kinase (MEK) and extracellular signal-regulated kinase 1/2 signaling; how

167 was transactivated by Src family kinases and extracellular signal-regulated kinase 1/2 was activated

168 nase p38 was enhanced and phosphorylation of extracellular signal-regulated kinase 1/2 was decreased

169 r and activator of transcription 5, AKT, and extracellular signal-regulated kinase 1/2, determining i

170 ory effects, increased inhibition of phospho-extracellular signal-regulated kinase 1/2, increased mit

171 nt phosphorylation of the downstream kinases extracellular signal-regulated kinase 1/2, mitogen-activ

172 ey signaling intermediates protein kinase B, extracellular signal-regulated kinase 1/2, NF-kappaB, an

173 ng MMP-9 secretion through the activation of extracellular signal-regulated kinase 1/2, p38, phosphoi

174 Strategies to inhibit extracellular signal-regulated kinase 1/2, ribosomal S6

175 STAT3, which is significantly enhanced by an extracellular signal-regulated kinase 1/2-dependent mTOR

176 ed activation of cardiac fibroblasts through extracellular signal-regulated kinase 1/2-dependent phos

177 emic retinopathy selectively activates GPR81-extracellular signal-regulated kinase 1/2-Norrin signali

178 The most frequent extracellular signal-regulated kinase 2 (ERK2) mutation

179 ind the nonphosphorylated (inactive) form of extracellular signal-regulated kinase 2 (ERK2) or its do

180 hanistic studies revealed that activation of extracellular signal-regulated kinase 5 (ERK5) via upreg

181 gen-activated protein kinase kinase 5)-ERK5 (extracellular signal-regulated kinase 5) signaling and c

182 teraction network, which includes the kinase extracellular signal-regulated kinase 7 (ERK7).

183 -function variant-mediated Ca(2+) influx and extracellular signal-regulated kinase activation in HEK

184 reactive oxygen species production, and p38/extracellular signal-regulated kinase activation in mast

185 growth factor receptor signalling, including extracellular signal-regulated kinase activation, to dri

186 Spine growth required extracellular signal-regulated kinase activation, while

187 oncomitant down-regulation of phosphorylated extracellular signal-regulated kinase and myeloid cell l

188 orters, mRNAs, signaling (phosphorylation of extracellular signal-regulated kinase and phospholamban)

189 Finally, combined inhibition of the Raf/MAPK/extracellular signal-regulated kinase axis and eIF4E imp

190 cal analysis of the MAP2K1 downstream target extracellular signal-regulated kinase demonstrated its p

191 ingly, knockdown of the canonical downstream extracellular signal-regulated kinase did not reproduce

192 Acquired BRAF/MAPK/extracellular signal-regulated kinase inhibitor resistan

193 nib and the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor selumeti

194 as EGFR or mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)/ERK i

195 anomas frequently develop resistance to MAPK/extracellular signal-regulated kinase kinase inhibitors

196 6 on both MEK-ERK (mitogen-activated protein/extracellular signal-regulated kinase kinase-extracellul

197 and a synthetic lethal interaction with the extracellular signal-regulated kinase mitogen-activated

198 ls a new functional role for cocaine-induced extracellular signal-regulated kinase pathway independen

199 to enhance the efficacy of BRAF-MAPK kinase-extracellular signal-regulated kinase pathway inhibition

200 rvival signaling pathways, including the MEK-extracellular signal-regulated kinase pathway.

201 cillatory magnitudes via modulation of local extracellular signal-regulated kinase phosphorylation (p

202 ression in primary OA chondrocytes inhibited extracellular signal-regulated kinase phosphorylation in

203 a role of this holoenzyme in suppression of extracellular signal-regulated kinase signaling and prot

204 Notably, inhibition of Raf/MAPK/extracellular signal-regulated kinase signaling decrease

205 nd enhance or diminish AKT Ser/Thr kinase or extracellular signal-regulated kinase signaling in a bia

206 Instead, enhanced phosphorylated extracellular signal-regulated kinase signaling in Wolff

207 e of knockout mice, suggesting that impaired extracellular signal-regulated kinase signaling mediated

208 g family, pyrin domain-containing-3, and p38/extracellular signal-regulated kinase signaling pathways

209 ired to maintain normal cardiac function via extracellular signal-regulated kinase signaling.

210 NF release and tropomyosin receptor kinase B-extracellular signal-regulated kinase signaling.

211 nd clearance by alveolar macrophages through extracellular signal-regulated kinase signaling.

212 ular, disruption of mGlu5 phosphorylation by extracellular signal-regulated kinase within this brain

213 nflammatory molecules and activation of ERK (extracellular signal-regulated kinase) 5/p38 pathways.

214 extracellular signal-regulated kinase kinase-extracellular signal-regulated kinase) and S6K-RPS6 (rib

215 inositol 1,4,5-triphosphate/protein kinase C/extracellular signal-regulated kinase) are major mediato

216 ted by MEK (mitogen-activated protein kinase/extracellular signal-regulated kinase) inhibition or c-J

217 , A61603 activation of cardioprotective ERK (extracellular signal-regulated kinase) was markedly impa

218 ct of each variant on the activation of ERK (extracellular signal-regulated kinase), AKT (protein kin

219 s and Pam3Cys led to phosphorylation of ERK (extracellular signal-regulated kinase), JNK, and p38 mit

220 Of note, a phosphorylated extracellular signal-regulated kinase+/BCL-XL(+) /myeloi

221 -fold, inactivated the key signaling protein extracellular signal-regulated kinase, and increased apo

222 ormation, possibly through protein kinase B, extracellular signal-regulated kinase, and NF-kappaB pat

223 nsducer and activator of transcription 5 and extracellular signal-regulated kinase, and transforms pa

224 nsducer and activator of transcription 3 and extracellular signal-regulated kinase, as well as format

225 and three mitogen-activated protein kinases (extracellular signal-regulated kinase, c-Jun N-terminal

226 Other synaptic proteins, such as extracellular signal-regulated kinase, calcium/calmoduli

227 ACD-induced cytoskeletal collapse activated extracellular signal-regulated kinase, p38, and c-Jun am

228 of K-Ras effectors, including phosphorylated extracellular signal-regulated kinase, phosphorylated pr

229 /calmodulin-dependent protein kinase II, and extracellular signal-regulated kinase, play key roles in

230 atidylinositol 3-kinase-Akt, Ras-Raf-1, MEK1/extracellular signal-regulated kinase, sphingolipid, and

231 Key roles were identified for extracellular signal-regulated kinase-1/2, p38alpha kina

232 that TRAF1 is required for solar UV-induced extracellular signal-regulated kinase-5 (ERK5) phosphory

233 1P receptor 3 (S1pr3) through Rho kinase and extracellular signal-regulated kinase-dependent pathway.

234 The extracellular signal-regulated kinase-ribosomal S6 PK-ph

235 osphorylation of phospholipase C gamma-1 and extracellular signal-regulated kinase.

236 r and activator of transcription 5, Akt, and extracellular signal-regulated kinase.

237 kinase interacting kinase-1, downstream from extracellular signal-regulated kinase.

238 The RAS-ERK/MAPK (RAS-extracellular signal-regulated kinase/mitogen-activated

239 ncrease in phosphorylation and activation of extracellular signal-regulated kinase/mitogen-activated

240 e characterized by overactivation of ERK1/2 (extracellular signal-regulated kinase1-/2), AKT (protein

241 leading to protein kinase C/protein kinase D/extracellular signal-regulated kinase1/2 pathway activat

242 y inhibitors of the prolyl isomerase Pin1 or extracellular signal-regulated kinases (ERK) 1/2 or by p

243 The Ras/PI3K/extracellular signal-regulated kinases (ERK) signaling n

244 (JNK), the Axl receptor tyrosine kinase and extracellular signal-regulated kinases (ERK).

245 ind that the proteinase ADAM17 activates the extracellular signal-regulated kinases (ERK1/2) pathway

246 Here, we show that extracellular signal-regulated kinases (ERK1/2) respond

247 Additionally, the ratio of activated extracellular signal-regulated kinases (pERK) or pAkt to

248 carcinoma (HCT116) cells treated with H2O2, extracellular signal-regulated kinases 1 and 2 (ERK1/2)

249 activation of phosphoinositide 3-kinase and extracellular signal-regulated kinases 1 and 2 by Gbetag

250 ion of p38 mitogen-activated protein kinase, extracellular signal-regulated kinases 1 and 2, and Jun

251 a resulted in reduced phosphorylation of the extracellular signal-regulated kinases 1 and 2, enhanced

252 ethyl-D-aspartate receptors or activation of extracellular signal-regulated kinases 1 and 2, or block

253 eported mediator in vibratory urticaria, and extracellular signal-regulated kinases 1/2 activation wa

254 ase C, and phosphoinositide 3-kinase but not extracellular signal-regulated kinases 1/2 pathways, alo

255 oduction and produced enduring activation of extracellular signal-regulated kinases 1/2 phosphorylati

256 causally linked with excessive activation of extracellular signal-regulated kinases in striatal neuro

257 iratory epithelial cells is regulated by the extracellular signal-regulated protein kinase (ERK) mito

258 ietic protein tyrosine phosphatase, controls extracellular signal-regulated protein kinase 1/2 (ERK1/

259 Whereas thrombin-induced extracellular signal-regulated protein kinase 1/2 (ERK1/

260 he mitogen-activated protein kinase 1 (i.e., extracellular signal-regulated protein kinase 2, ERK2),

261 Extracellular signal-regulated protein kinase 5 (ERK5) h

262 ld largely rule out the stress-activated and extracellular signal-regulated protein kinase modules an

263 complex and subsequent signaling through the extracellular signal-regulated protein kinases 1 and 2 (

264 uired for agonist-induced phosphorylation of extracellular signal-regulated protein kinases 1 and 2 (

265 tion while reducing fibroblast growth factor/extracellular signaling-regulated kinase 1/2 activity in

266 r of mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinase (ERK) (MEK) 1/2, w

267 se protein, which binds and dephosphorylates extracellular-signal-regulated kinase (ERK), leading to

268 inositol-3'-kinase/protein kinase B and KRAS/extracellular-signal-regulated kinase signaling pathways

269 ed B cells-p65, increased phosphorylation of extracellular-signal-regulated kinase, and reduced the e

270 tivates the mitogen-activated protein kinase extracellular-signal-regulated kinase, which then direct

271 Extracellular-signal-regulated kinases (ERK) 1 and 2 reg

272 region in the striatum, including the kinase extracellular-signal related kinase 1 (ERK1).

273 k on mitogen-activated protein kinase (MAPK)/extracellular signal-related kinase (ERK) (MEK) biology

274 L binding inhibits BIM-EL phosphorylation by extracellular signal-related kinase (ERK) on serine 69.

275 ponses to Toll-like receptor 2 (TLR2)-driven extracellular signal-related kinase (ERK) signaling in d

276 lity by combining optogenetic control of Ras/extracellular signal-related kinase (ERK) signaling with

277 Western blots measured protein levels of extracellular signal-related kinase (ERK), Akt, TRalpha1

278 The extracellular signal-related kinase 1 and 2 (ERK1/2) pat

279 hypothalamic distribution of phosphorylated extracellular signal-related kinase 1/2 (pERK1/2), a mar

280 r claudin-1 knockdown, and protein levels of extracellular signal-related kinase 1/2 were reduced.

281 tor (TR)alpha1 abolishes T(3) signalling via extracellular signal-related kinase and Akt in fetal car

282 gulates the mitogen-activated protein kinase/extracellular signal-related kinase pathway and induces

283 ling molecules Src (Src family kinase), ERK (extracellular signal-related kinase), and VASP (vasodila

284 1 prevented IL-33-induced phosphorylation of extracellular signal-related kinase, an upstream effecto

285 d cyst epithelial cell proliferation through extracellular signal-related kinase/MAPK inactivation.

286 mitogen-activated protein kinase (p38MAPK), extracellular signal-related kinases (ERKs), protein kin

287 gnal mediators to transduce information from extracellular signals such as neurotransmitters, hormone

288 te potentiates pathogenicity by acting as an extracellular signal that inhibits phagosome maturation.

289 n state of satellite cells, but the specific extracellular signals that coordinate this regulation ar

290 excitatory synapse generated large negative extracellular signals that nonsynaptically inhibited nei

291 dients, morphogens drive graded responses to extracellular signals, thereby fine-tuning cell behavior

292 This capacity depends on the integration of extracellular signaling through multiple receptors, incl

293 control signaling specificity from a single extracellular signal to multiple cellular processes.

294 The intrinsic mechanisms that link extracellular signalling to the onset of neural differen

295 phosphorylation, suggesting CAP1 may mediate extracellular signals to control cancer cell invasivenes

296 is well established, how these interact with extracellular signals to regulate interneuron developmen

297 Cells relay a plethora of extracellular signals to specific cellular responses by

298 regulation to diverse natural and synthetic extracellular signals via GPCRs.

299 various cell surface receptors to integrate extracellular signals with developmental programs.

300 suring appropriate response of stem cells to extracellular signals, with important implications for d