ライフサイエンスコーパス: eye color

1 r the enhancer variant responsible for light eye color.

2 sun tanning responses, ethnicity, hair, and eye color.

3 integrants simply by the loss of mini-white eye color.

4 enetic system in which many mutations affect eye color.

5 omere region can be identified by changes in eye color.

6 function mutations at eight loci that affect eye color.

7 an effect on the OAER due to photophobia or eye color.

8 lting in heritable epigenetic differences in eye color.

9 indicating a role for these pigments beyond eye color.

10 ons and evolutionary drivers of variation in eye color.

11 pean Americans in the replication stage (for eye color, 3871 males in the discovery stage and 2496 ma

12 butable to genetic effects: 7% associated to eye color, 6% to hair color, and 1% to reported skin typ

13 dence for two new pigmentation loci: one for eye color (AHRR) and one for skin color (DDB1).

14 ery prune allele to date exhibits both prune eye color and prune/Killer of prune lethality.

15 taken of constitutional risk factors such as eye color and skin reflectance.

16 riation in phenotypic traits such as height, eye color and susceptibility to disease.

17 ed host phenotypes (such as pigmentation and eye color) and tested them for association with UM risk.

18 ous knowledge and expectations, highlighting eye color as a genetically highly complex human trait.

19 th whom they shared their ethnicity, sex, or eye color as significantly more trustworthy.

20 ue, intermediate (including green) and brown eye colors as co-dominant outcomes, we identified the SN

21 Male sex, age, lighter hair and eye color, baldness, genetic risk score, and digital pho

22 ht, weight, waist:hip ratio, skin, hair, and eye color, blood pressure, and grip strength.

23 The EABH detects Fe(2+) by "naked eye" color change from lime yellow to brown and displaye

24 nstrate that the genetic complexity of human eye color considerably exceeds previous knowledge and ex

25 a putative coat adaptor protein leads to the eye color defect of garnet mutants.

26 aracterized by defective platelets, coat and eye color dilution, lysosomal abnormalities, inner ear d

27 In the adult Drosophila compound eye, color discrimination is achieved by UV-, blue- and

28 Changes in eye color due to altered expression of the transgene als

29 e of Drosophila melanogaster result in prune eye color due to reductions in red pigment accumulation.

30 cally relevant SNPs associated with hair and eye color, facial morphology, and myopia, imply strong g

31 of RNAi is effective for both the white (w) eye color gene and green fluorescent protein (GFP), indi

32 modifiers of gene expression with the white eye color gene as a target, a third chromosomal P-elemen

33 s isolated in screens for modifiers of white eye color gene expression.

34 pendent trans-acting regulators of the white eye color gene in combinations to understand their inter

35 c expression of various alleles of the white eye color gene.

36 The imprinted gene - the white+ eye-color gene - is expressed at a low level when transm

37 tested whether variegated expression of the eye-color gene brown in Drosophila is influenced by its

38 orange and carnation are two of the classic eye color genes in Drosophila.

39 lar identification of two classic Drosophila eye-color genes required for pigment granule biogenesis,

40 The Tribolium orthologs of the Drosophila eye-color genes vermilion (tryptophan oxygenase) and cin

41 dels adjusted for age, sex, medical history, eye color, hair color, and likeliness of tanning versus

42 ecessive mutations at several loci affecting eye color imply that our EMS treatment was equivalent to

43 n the oocyte, is observed as white or mosaic eye color in F1 progeny.

44 n the region of HERC2/OCA2, which determines eye-color in the human population.

45 6/Hps6 double mutant mice mimic, in coat and eye colors, in melanosome ultrastructure, and in levels

46 d skin color; notably, 50% of variability in eye color is associated with variation in the SNP rs1291

47 Human eye color is highly heritable, but its genetic architect

48 Eye color is largely genetically determined and is defin

49 ssion patterns of the transgene's mini-white eye-color marker.

50 exogenous DNA yielded a frequency of somatic eye-color mosaicism of approximately 10% and a frequency

51 The use of eye-color mutants and their corresponding genes as scora

52 These results provide direct evidence that eye color mutations of the granule group also disrupt ve

53 Five available eye-color mutations were tested for linkage to Tcv or Tc

54 rs12913832 (HERC2), which is related to blue eye color, not only is a genetic factor related to the r

55 nome-wide association studies on hair color, eye color, number of sunburns, tanning ability and numbe

56 To change the eye color of the fly, we tested the CRISPR/Cas9 method w

57 while longer arrays increase the background eye color or increase the number of spots sufficiently t

58 nburns (OR, 2.59 [95% CI, 1.31-5.10]), light eye color (OR, 2.47 [95% CI, 1.30-4.67]), and less of an

59 rs12913832 in the OCA2 gene region on brown eye color (P-value for interaction = 3.8 x 10(-3)).

60 age of a Drosophila strain with a variegated eye color phenotype that is sensitive to heterochromatin

61 ackaging domains can be distinguished by the eye color phenotype.

62 ull alleles of prune are viable but cause an eye-color phenotype.

63 Using the eye color phenotypes associated with the inserts as visi

64 Thus, Drosophila with variegated eye color phenotypes could be an effective tool for scre

65 on cassettes results in flies with different eye color phenotypes due to position effects at the site

66 effect, observed as a highly skewed ratio of eye-color phenotypes in the F2 generation.

67 were uploaded onto the HIrisPlex webtool for eye color prediction.

68 g a mini-white construct can exhibit various eye colors ranging from pale orange to intense red, depe

69 ps between qAF and age, sex, race/ethnicity, eye color, refraction/axial length, and smoking status w

70 ed because they derepressed an MSL-dependent eye color reporter.

71 We describe a simple eye-color screen that facilitates isolation and analysis

72 of rs12913832 (HERC2), which codes for blue eye color showed a worse prognosis (P = 0.017) and more

73 Patients with a genetically blue eye color showed worse survival (P = 0.04).

74 hat solicited information on skin, hair, and eye color; skin cancer family history; and sun exposure

75 ts with UM and performed sequencing, using 6 eye color SNPs from the HIrisPlex-S assay (Erasmus MC, W

76 We tested the association of eye color SNPs with tumor characteristics and chromosome

77 he largest genome-wide association study for eye color to date, involving up to 192,986 European part

78 nerated synthetic PLR recordings for various eye colors to validate our method.

79 (95% confidence interval, 45.4 to 61.0%) of eye color variation using common single-nucleotide polym

80 Eye color was not commonly described as brown or green b

81 The transgene-mediated complementation of eye color was observed to segregate in a Mendelian manne

82 cts, using smartphone cameras with different eye colors, was also collected to demonstrate the method

83 Heavy smoking, sunscreen use, and green eye color were associated with genus-specific HPV seropo

84 sociated with common traits such as hair and eye color, while others are associated with susceptibili

85 e those coding for lactase persistence, blue eye color, Y chromosome R1b haplotypes, and the hemochro