ライフサイエンスコーパス: female mice

1 ed NF-kappaB activation in oligodendrocytes (female mice).

2 egeneration, without affecting inflammation (female mice).

3 ction under normal conditions (both male and female mice).

4 xpansion of DRG macrophages in both male and female mice.

5 ) normal and injured spinal cord of male and female mice.

6 due to fewer osteoclasts specifically in the female mice.

7 n receptor agonist were observed in male and female mice.

8 the meninges and cerebral cortex of male and female mice.

9 sory olfactory bulb output in awake male and female mice.

10 ical and trabecular compartments of male and female mice.

11 ory signature of livers in 19-month-old aged female mice.

12 s depression-like phenotypes in male but not female mice.

13 sympathetic innervation of iWAT in male and female mice.

14 immunological aspects in the colon of adult female mice.

15 al recovery in young and aged male and young female mice.

16 o synaptic plasticity in the DLS of male and female mice.

17 formation of estrogen-induced gallstones in female mice.

18 and galanin expression in the LC of male and female mice.

19 mRNA in the inferior colliculus of male and female mice.

20 changes, leading to neuropathic pain only in female mice.

21 loyed social buffering paradigms in male and female mice.

22 al (LS), and nodose ganglia (NG) in male and female mice.

23 se neurons after repeated stress in male and female mice.

24 type by inducing stress resilience solely in female mice.

25 ural regulatory T (T(reg)) cells in pregnant female mice.

26 2 (ChR2) in type I GAD65(+) TBCs of male and female mice.

27 s, which was increased in the translatome of female mice.

28 ively correlated with liver triglycerides in female mice.

29 which these are interrelated, using male and female mice.

30 ral myelination after birth in both male and female mice.

31 icotropin-releasing hormone (CRH) neurons in female mice.

32 mice but was only effective at high doses in female mice.

33 fields of male mice but only in the mPFC of female mice.

34 diurnal glycemic control in normal male and female mice.

35 Experiments were performed in both male and female mice.

36 from the brain, was altered between male and female mice.

37 l inhibition of the VP 1a receptor (V1aR) in female mice.

38 y in corticostriatal projections in male and female mice.

39 ulation of fear memory retrieval in male and female mice.

40 or loss and glucose homeostasis in male vs. female mice.

41 nd activated microglia in 3xTg/SPKO male and female mice.

42 hial nucleus, elicited USVs in both male and female mice.

43 ung (3-weeks) and mature (16-weeks) male and female mice.

44 g and thermogenic gene expression in male or female mice.

45 dification and reduced RGC death in male and female mice.

46 ng pulmonary sequelae is similar in male and female mice.

47 -hydroxynonenal (4-HNE) in the inner ears of female mice.

48 dia muridarum and they were caged with naive female mice.

49 , 9-, and 18-mo-old APOE3 and APOE4 male and female mice.

50 1(Deltaot)) alters bone mass and strength in female mice.

51 ession of miR-128 (Lm128C cells) in male and female mice.

52 tenance of chronic pain symptoms in male and female mice.

53 synaptic glutamatergic function in male and female mice.

54 ve nociceptors in the TG and DRG of male and female mice.

55 s in cAMP levels affect behavior in male and female mice.

56 d in unmanipulated, immunocompetent male and female mice.

57 e acquired on orbit from 16- and 32-week-old female mice.

58 at 6 months postinfection for both male and female mice.

59 njury, inflammation and fibrosis in male and female mice.

60 hen transferred to cages holding 'recipient' female mice.

61 (Col1a1(tm1Jae/+), mCol1a1) syngeneic FVB/N female mice.

62 ot linked to heightened glucose tolerance in female mice.

63 drives pain aversive states in male but not female mice.

64 zed and awake visual cortex in both male and female mice.

65 ine- and (2R,6R)-HNK-mediated prophylaxis in female mice.

66 s to lifelong alterations in life history in female mice.

67 erone and causes susceptibility to stress in female mice.

68 ons from Ntsr1-EGFP; Foxp2(+/R552H) male and female mice.

69 tion of this circuit prevents this effect in female mice.

70 duced thermogenic genes in SAT from male and female mice.

71 w-derived macrophages or in SAT from male or female mice.

72 on (alpha) in the ex vivo retina of male and female mice.

73 KO compared with single endothelial Bmp2 KO female mice.

74 erexcitability of trigeminal neurons from WT female mice.

75 333 attenuated learned fear in male, but not female mice.

76 to the olfactory bulbs of wild type male and female mice.

77 frequency trajectories in auditory cortex of female mice.

78 , Cd36, Acaab1, Fabp2, and Gdf15 in male and female mice.

79 GM-CSF) in nociceptor activation in male and female mice.

80 uritogen-induced scratching in both male and female mice.

81 fficacy of (R,S)-ketamine and (2R,6R)-HNK in female mice.

82 psaicin and menthol-evoked responses only in female mice.

83 mals (+115%; p < 0.05), but was unchanged in female mice.

84 ers colon morphology and physiology in adult female mice.

85 e secretion and body growth in both male and female mice.

86 r global cerebral ischemia (GCI) in male and female mice.

87 Female mice acquired the correct image-value association

88 In male and female mice, acute perturbation of the cerebellar vermis

89 elevated in plasma collected from NOD/ShiLtJ female mice after disease onset, whereas these drastic c

90 n submandibular glands (SMG) from NOD/ShiLtJ female mice after disease onset, with 5-LOX and 12/15-LO

91 no significant difference in either male or female mice after GABA(A)R gamma2 subunit reduction in t

92 The effect of HFD was more pronounced in female mice after VDR deletion.

93 In adulthood, IRKOGFAP female mice also exhibited longer, irregular estrus cycl

94 ween ovarian hormones and stress resilience, female mice also underwent ovariectomy (OVX) surgery and

95 Male, but not female, mice also exhibited ISRIB-mediated protection ag

96 gut microbiota composition in both male and female mice, although the specific microboal taxa altere

97 ced hyperphagia and obesity in both male and female mice, an effect prevented by viral rescue of ACBP

98 ately 2 fold (p < 0.05) in heart tissue from female mice and about 150% (p < 0.05) in male mice.

99 owever, fewer macrophages are induced in the female mice and deletion of colony-stimulating factor 1

100 charin preference, and behavioral despair in female mice and enhanced stress-induced decrease in sucr

101 eek-old (P28) and 12-week-old (P84) male and female mice and found that DSD is lower in female mice d

102 ng the ethanol sensitivity of VTA neurons in female mice and found that ERalpha promotes the enhanced

103 Here we examined the effects of MAS on female mice and probed the role of hormonal fluctuations

104 on channel Trpc5 in prolactin homeostasis of female mice and provide strategies to explore the geneti

105 using neuron cultures prepared from male and female mice and rats.

106 Here we analyze male and female mice and show that HBCs also are activated with i

107 uronal cell counts significantly in male and female mice and tended to decrease subunit C storage in

108 function and gene expression selectively in female mice and, along with studies of human neuron-like

109 , depressive-like and anhedonic behaviors in female mice, and altered microglial metabolic reprogramm

110 ion of TRKB in vitro and in vivo in male and female mice, and juvenile-like plasticity is retained in

111 Overall, female mice appear more susceptible to signs of ocular p

112 that, during high E2 states, VTA neurons in female mice are more sensitive to ethanol excitation.

113 valuate the underlying mechanism(s) by which female mice are protected against obesity-induced insuli

114 ese findings, we observed that Ikbkap mutant female mice are subfertile.

115 d in Tet2/3(fl/fl)Foxp3(WT/Cre) heterozygous female mice are unable to rescue the aberrant properties

116 that norBNI does not work as effectively in female mice as in males because of estrogen regulation o

117 a mechanism may be functionally relevant in female mice as well.

118 al growth factor-A (VEGF-A) in both male and female mice, as well as increased VEGFR1 and interleukin

119 etabolome and the gut microbiota of male and female mice at 5, 10, and 15 months to capture the dynam

120 re comparable to pituitary levels from adult female mice at proestrus and GnRHR mRNA in decidua was e

121 Male mice were nearly as effective as female mice at reducing the bacterial burden either with

122 dization analyses of both male and recipient female mice at the study endpoint.

123 Male but not female mice born to dams harboring polyclonal anti-Caspr

124 ssive- and anxiety-like behavior in male and female mice, both before and after a sex-specific chroni

125 crease susceptible to gallstone formation in female mice; both GPR30 and ERalpha are potential therap

126 n, Lgmn evoked nociception in wild-type (WT) female mice but not in female mice lacking PAR(2) in Na(

127 novel object recognition in aged Tmprss9-/- female mice, but not in aged Tmprss9-/- male mice or you

128 ion of Sult1e1 in the liver in both male and female mice, but Sult1e1 induction in the kidney occurre

129 Reproductive decline in older female mice can be attributed to a failure of the uterus

130 By analyzing female mice carrying targeted mutations in the Trpc5 gen

131 that neurogenesis was disrupted in male and female mice chronically deficient for two phagocytosis p

132 psin into the visual cortex of both male and female mice, closed one eyelid for 4-5 d, and, as expect

133 We used novel genetic strategies in male and female mice combined with electrophysiological and morph

134 d disease course in cortactin gene-deficient female mice compared with WT mice.

135 iod increases sensitivity to adult stress in female mice, consistent with our earlier findings in mal

136 ampal local field potential in both male and female mice demonstrate that Scn1a haploinsufficiency sl

137 rees (x/lox)/Osx-Cre(+/-) genotypic male and female mice (designated postnatal-OIRKO).

138 del of early-life exercise (ELE) in male and female mice designed with the goal of identifying critic

139 ent in a murine model, showing that male and female mice develop mechanical hypersensitivity 24 h aft

140 In this model, female mice develop mechanical hypersensitivity in the c

141 However, at 9-14 days, the myocardium of female mice developed marked elevations in free fatty ac

142 d female mice and found that DSD is lower in female mice due in part to fewer short stubby, long stub

143 ariectomized (OVX) and OVX+estradiol (OVX+E) female mice during estradiol negative feedback revealed

144 ressive behavior in male mice, it reduces in female mice evoked-depression only.

145 son with males, high-fat diet (HFD) allergic female mice exhibit a reduction in the number of leucocy

146 mpared with E4bp4(flox/flox) mice, E4bp4-LKO female mice exhibit reduced liver lipid accumulation and

147 Remarkably, we found that female mice exhibited no immediate changes in accelerati

148 Female mice exhibiting RFRP neuron ablation or silencing

149 Female mice exposed neonatally to the phytoestrogen geni

150 In addition, female mice exposed to LAN increased central tendency in

151 We showed that great-great-grandsons of female mice exposed to tributyltin (TBT) throughout preg

152 Similarly, HFD female mice express lower levels of EpCAM in lung tissue

153 ression in lung tissue demonstrated that HFD female mice express lower levels of these regulatory fac

154 cretion, and insulin sensitivity in male and female mice expressing either the NOER or the MOER.

155 In male and female mice expressing tdTomato in Y(2)R-mRNA cells (tdT

156 phages differentiated in vitro from male and female mice fed control or high-fat diet, we demonstrate

157 51, was consistently upregulated in male and female mice following stress.

158 twice daily by oral gavage) to 5 months old female mice for 5 days.

159 the novel PlxnA4(KRK-AAA) knock-in male and female mice, generated by CRISPR/cas9, we show here that

160 Here, we show that female mice genetically ablated for cyclin B3 are viable

161 cells within three brain regions of male and female mice: GPe, striatum, and cortex.

162 Female mice had higher baseline wave-I amplitudes but gr

163 6-month male and female mice had only intracellular pathology and male mi

164 overtly diabetic at ~5 weeks of age, whereas female mice had only slightly elevated nonfasting glycem

165 Multiparous female mice had significantly decreased beta-cell Glp1r

166 In the cerebral cortex, female mice had two-fold more genes responding to nPM th

167 We conclude that exposure to EHS in female mice has the capacity to cause delayed metabolic

168 All female mice have a faster nerve regeneration rate than m

169 Keratin14-Cre or in B cells using CD19-Cre, female mice have a normal life span without obvious illn

170 and that bone marrow neutrophils (BMN) from female mice have an enhanced ability to kill S. aureus e

171 -induced ocular pain and anxiety in male and female mice have not been characterized.

172 Behavior tests indicate that Fam19a1 KO female mice have reduced anxiety and sensitivity to pain

173 SETD3-deficient female mice have severely decreased litter sizes owing t

174 es, however, less is known regarding whether female mice have sufficient intrasexual competition to e

175 pplied synthetic Abeta oligomers in male and female mice heterozygous for either a PME-1 KO or an LCM

176 ronic 10 bp deletion (del10) in Hgf Male and female mice homozygous for del10 exhibit moderate-to-pro

177 Female mice housed with sham-infected males had no posit

178 D1-Cre, A2A-Cre, or vGluT2-Cre:Ai9 male and female mice in a cocaine conditioned place preference pr

179 nsory selection process, we trained male and female mice in a selective detection task in which mice

180 We studied male and female mice in age-matched or body weight-matched condit

181 the effects of cagemate presence in male and female mice in learned and innate fear contexts without

182 tudy revealed a predominant role of Tregs in female mice in promoting adipocyte beiging and thermogen

183 We found no differences between male and female mice in the baseline pulmonary expression of key

184 idbrain, a decrease with age was observed in female mice in the same regions.

185 tory corticocollicular neurons from male and female mice in vitro Layer 5 corticocollicular neurons w

186 ished the protection in male mice but not in female mice, indicating that Sult1e1's effect on AKI was

187 earning and pain responses preferentially in female mice, indicating that the effects of H2A.Z depend

188 DNA (mtDNA) and nuclear DNA (nDNA) damage in female mice, indicative of the sex-driven differential r

189 t deletion of both CAMK2 isoforms in male or female mice is lethal.

190 e results demonstrate that the myocardium of female mice is vulnerable to a slowly emerging metabolic

191 on and blunted drug-induced reinstatement in female mice, it had the opposite effect in male mice.

192 al prefrontal cortex (mPFC), in male but not female mice lacking AdipoR1 in 5-HT neurons.

193 my unexpectedly promotes midlife survival of female mice lacking hepatic mTORC2, significantly increa

194 ion in wild-type (WT) female mice but not in female mice lacking PAR(2) in Na(V)1.8-positive neurons

195 s of interneuron transplantation in male and female mice lacking the autism-associated gene, Pten, in

196 Strikingly, both male and female mice lacking Tiam1 exhibit enhanced contextual fe

197 ctivated K(+) (SK) currents in both male and female mice, leading to decreased action potential (AP)

198 C57BL/6J female mice (n = 18) were first treated with antibiotics

199 In female mice nearing the end of their reproductive lifesp

200 knockout (KO) postnatal day 0 (P0) male and female mice on a C57BL/6J background, specific AVPR1A li

201 plementation with L lactis subsp cremoris in female mice on a high-fat, high-carbohydrate (Western-st

202 serum cholesterol, and insulin resistance in female mice on a high-fat, high-carbohydrate diet.

203 ad to increased anxiety-related behaviors in female mice only.

204 C57Bl/6 female mice oropharyngeally aspirated 200 ug of WTC-PM(5

205 addition, we also observed that allergic HFD female mice presented a robust lung remodelling in compa

206 hesion molecule expression, we observed that female mice presented a significantly lower expression o

207 nt changes were observed in neurons of adult female mice pretreated with LPS, nor in adolescent mice

208 f MAR-ASD-specific epitope autoantibodies in female mice prior to breeding created a model that demon

209 ncreased 24 hours after chronically defeated female mice received a systemic dose of ketamine.

210 -term outcome was not observed when male and female mice received ketamine as adults (PD70-84) and te

211 hen Xist is deleted in gut using Villin-Cre, female mice remain healthy despite significant X-autosom

212 havior in sexually naive and late postpartum female mice respectively, with no effect on sexually nai

213 mg.kg(-1) to 95 +/- 2 mg.kg(-1) for male and female mice, respectively.

214 n cells (DSGCs) from the retinas of male and female mice respond to a global motion stimulus with its

215 rank differentially influences how male and female mice respond to chronic stress.

216 Male and female mice responded differently to PCB-77 and AhR defi

217 Conversely, female mice responded more robustly to another major pro

218 Our data in both male and female mice reveal selective modulation of SST interneur

219 s in ex vivo brain slices made from male and female mice revealed a significant increase in excitator

220 ofiling of adipose tissues of HFD-fed UtxAKO female mice revealed decreased expression of rate-limiti

221 hoton calcium imaging of head-fixed male and female mice running on a treadmill, we find that only a

222 We demonstrate that in female mice, severe EHS results in metabolic changes in

223 Female mice showed a mild increase in body weight accomp

224 Birthdating in male and female mice showed that tuberal hypothalamic neurogenesi

225 a potential mediator of social buffering in female mice.SIGNIFICANCE STATEMENT In many organisms, in

226 hed that chronic adversity around puberty in female mice significantly altered their HPA axis functio

227 systemic administration of FK506 in male and female mice significantly increased the amount of alpha2

228 The influence of ERs on binge drinking in female mice suggests that treatments for alcohol use dis

229 For NASA's Rodent Research-1 mission, female mice (ten 32 wk C57BL/6NTac; ten 16 wk C57BL/6J)

230 We found that adult female mice that had been undernourished only from birth

231 eurons dissociated from cortices of male and female mice that the shift in mEPSC amplitudes observed

232 ORs and 3 TAARs in freely behaving male and female mice, the first example of in vivo responses of b

233 the follicular phase of the estrous cycle in female mice, the ketamine response was transiently atten

234 egrity, microglia activation, and fatigue in female mice, thus identifying a novel relationship betwe

235 We then performed behavioral studies in female mice to analyze learning and memory, and then tar

236 We used two-photon calcium imaging in female mice to characterize the disparity tuning propert

237 or Vgat-IRES-cre mice and used both male and female mice to confirm that the neurons that express EP3

238 dministration paradigm that allowed male and female mice to consume Delta(9)-tetrahydrocannabinol, ca

239 d unilateral whisker denervation in male and female mice to detect circuitry alterations underlying i

240 y, and immunoelectron microscopy in male and female mice to elucidate mechanisms in the vPAG that pro

241 ons, we used the anterior tongue of male and female mice to implement a slice preparation in which fu

242 l obstruction surgery on four male and three female mice to induce inflammation and fibrosis, collect

243 Modulating Kdm5c gene dosage in XX female mice to levels that are normally present in males

244 performed extracellular recordings in adult female mice to monitor the activity of putative pyramida

245 We exposed male and female mice to morphine for one week, with administratio

246 We exposed male and female mice to physiologically comparable amounts of PB

247 two-photon imaging in anesthetized male and female mice to record activation of MTCs while precisely

248 vermal cerebellum in awake behaving male and female mice to record granule neuron responses to divers

249 accumbens, and prefrontal cortex of male and female mice to show that adult stress is distinctly repr

250 e we use cortactin gene-inactivated male and female mice to study the role of this protein in EAE.

251 he ME7 model of chronic neurodegeneration in female mice, to examine vulnerability of the diseased br

252 .8-positive neurons (Par(2)Na(v)1.8), nor in female mice treated with a Lgmn inhibitor, LI-1.

253 However, C57BL/6J female mice treated with the benzimidazole inhibitor exh

254 of ERalpha neurons in the arcuate nucleus of female mice undergoes a shift in phenotype, from GHRH to

255 Female mice underwent forced wheel running at 37.5 degre

256 or expression in the hippocampus of male and female mice using PCR, Western blot, and immunofluoresce

257 In female mice, voluntary wheel running was decreased (P <

258 activation of AON neurons in awake male and female mice was not perceived as an odorant equivalent c

259 ation, overexpressed CX3CL1 in both male and female mice was sufficient to rescue the neurodegenerati

260 Bone marrow from WT and Esr1(-/-) female mice was transferred (1:1 ratio) into WT female r

261 ic stimulation in brain slices from male and female mice, we compared the properties of these PrL/IL-

262 2)-assisted circuit mapping in both male and female mice, we found that a subset of CeA neurons send

263 In models of chronic pain, using male and female mice, we found that Wnt5a is released spinally fr

264 In female mice, we observed DNA methylation reprogramming i

265 two-photon calcium imaging in adult male and female mice, we show that direction-selective neurons in

266 l of ischemic spinal cord injury in male and female mice, we show that preoperative LPSx4 provides co

267 wide-spectrum antibiotics and germ-free (GF) female mice, we showed that the microbiota was required

268 To study these mechanisms in male and female mice, we used in vitro and in vivo models of zinc

269 CD1 female mice were acutely fed a standard breeding chow or

270 Male and female mice were aged to 5- and 12-months and subjected

271 In contrast, lesions in Fap(-/-) female mice were characterized by a more fibrotic compos

272 ted effective human doses for adult male and female mice were comparable to those of other (18)F-base

273 To test this hypothesis, adult female mice were dosed with vehicle control or DiNP dose

274 Female mice were exposed to GEN on postnatal days (PND)1

275 Adult female mice were fed a normal chow (NC) or a high fat di

276 l LAN alters brain function, adult male, and female mice were housed in either light days and dark ni

277 Female mice were impacted by MAS in an estrous cycle-dep

278 Both male and female mice were included in this study.

279 To induce diabetes female mice were injected with a single high dose of str

280 We conducted olfactory assays and found that female mice were more attracted to the scent of dominant

281 Female mice were more likely to constrain their decision

282 Female mice were partially protected from alkylation-ind

283 Female mice were placed on either control (P-CD) or high

284 In the present study, C57BL/6J female mice were randomly assigned into two groups fed e

285 Female mice were sensitized to peanut intragastrically w

286 Both male and female mice were used in the present study.

287 C57BL/6 female mice were vaccinated 3 weeks apart with DeltagD-2

288 decreased alcohol drinking in both male and female mice, whereas KOR knockout decreased drinking in

289 neurons increases itch behavior in male and female mice, whereas pharmacological inhibition of spina

290 ructural probes to equal numbers of male and female mice with a hearing phenotype akin to human aging

291 Female mice with a muscle-specific deficiency in BDNF (M

292 deletion attenuated mechanical allodynia in female mice with carcinogen-induced OSCC.

293 In female mice with experimental autoimmune encephalomyelit

294 at cortices of both sexes and young male and female mice with oligodendrocyte-specific deletion of me

295 In female mice with pre-established obesity, Treg adoptive

296 Housing C57BL/6J female mice with sterilized males early in life led to a

297 r kinase (GRK); pretreatment of ovary-intact female mice with the selective GRK2/3 inhibitor, Compoun

298 fter large ischemic cortical injury in adult female mice, with a focus on factors that might influenc

299 we show that maternal experience in WT adult female mice (WT) triggers suppression of PV auditory res

300 y eye produces more severe corneal damage in female mice, yet signs of LGE-induced ocular pain and an