ライフサイエンスコーパス: fimbria

1 iotic piglets expressing receptors for F4(+) fimbria.

2 e that regulated the phase variation of MR/P fimbria.

3 dominant species expressed in the developing fimbria.

4 and eventually away into the alveus, and the fimbria.

5 iously identified as the P. gingivalis minor fimbria.

6 the antigenically variable epitopes of that fimbria.

7 ls of serum IgG and mucosal IgA against 987P fimbria.

8 ch encodes another important UPEC adhesin, P fimbria.

9 egions required for expression of the AAF/II fimbria.

10 on of TosR synthesis reduces production of P fimbria.

11 eviously described tip protein of the type 2 fimbria.

12 ncers, ovarian cancer cell lines, and normal fimbria.

13 at are specific to either the K88ac or K88ad fimbria.

14 ed the binding activity of each K88 chimeric fimbria.

15 d linked to a serous cancer precursor in the fimbria.

16 tively affected the binding capacity of each fimbria.

17 ning to detect microscopic carcinomas in the fimbria.

18 We have recently demonstrated that type 1 fimbria, a phase-variable virulence factor involved in a

19 associated with the Actinomyces oris type 2 fimbria, a surface structure assembled by sortase (SrtC2

20 ded by one of the two pap operons encoding P fimbria adherence factor, represses flagella-mediated mo

21 ymphocytes during C trachomatis infection of fimbria and ampulla autografts in subcutaneous pockets i

22 ciencies of adult myelination in hippocampal fimbria and mild working memory deficits.

23 y present in the angular bundle, alveus, and fimbria and relatively scant immunoreactivity in the nas

24 o evaluate the role of CA3 efferents via the fimbria and the CA1 efferents via the dorsal fornix for

25 igodendrocyte myelination in the hippocampal fimbria and the corpus callosum during development, and

26 )) produced systemic antibodies against both fimbria and the TGEV C epitope but not against the TGEV

27 n inflammatory stimulus into the area of the fimbria and transplanting enhanced green fluorescent pro

28 omposed of MrpH, the tip adhesin of the MR/P fimbria, and cholera toxin to prevent urinary tract infe

29 own-regulation of motility, acid resistance, fimbria, and curlin genes.

30 fiber tracts, including the corpus callosum, fimbria, and internal capsule in the brain, and pyramida

31 alysis of the matrisome fraction between FT, fimbria, and ovaries showed significant differences in t

32 e also found in the body of the fornix, left fimbria, and superior longitudinal fasciculus (SLF).

33 and sRNA350--were shown to regulate urease, fimbria, and the LEE, respectively.

34 campal commissure, septohippocampal nucleus, fimbria, anteroventral thalamic nucleus, frontal and par

35 ells inhibited invasion, but the anti-type-C-fimbria antibody inhibited invasion to a greater extent

36 aqueductal gray matter ( approximately 13%), fimbria ( approximately 18%), and anterior commissure (

37 discuss the emergence of the fallopian tube fimbria as a field of origin for high-grade serous carci

38 the chaperone-subunit complex led to delayed fimbria assembly, whereas destabilizing the complex resu

39 ing an energetic landscape unique to class 5 fimbria assembly.

40 tite (SHA), or in its ability to express the fimbria-associated adhesin Fap1.

41 hrlichiosis agent 130-kDa protein and of the fimbria-associated adhesin protein Fap1 of Streptococcus

42 Mature Fap1, a 200-kDa fimbria-associated adhesin, is required for fimbrial bio

43 tudies in our laboratory have identified two fimbria-associated adhesins, FimA and Fap1, of Streptoco

44 Fap1, a fimbria-associated glycoprotein, is essential for biofil

45 The fimbria-associated MrkD1P protein mediates adherence of

46 fimbrial genes resulted in severe defects in fimbria-associated phenotypes, revealing roles in cell-c

47 FimH consists of a fimbria-associated pilin domain and a mannose-binding le

48 Fimbria-associated protein 1 (Fap1) is a high-molecular-

49 A fimbria-associated protein, Fap1, is identified as an ad

50 d to each other and to genes that may encode fimbria-associated proteins.

51 Fap1, a fimbria-associated serine-rich glycoprotein, is required

52 n and biofilm formation are independent of a fimbria-associated serine-rich repeat adhesin, Fap1, dem

53 ition of hemagglutination induced by class 5 fimbria-bearing ETEC.

54 is critical for the biogenesis of a type IV fimbria because of the essential role of a disulphide bo

55 presubiculum (beta=-0.29, p=0.030), and left fimbria (beta=-0.30, p=0.023).

56 unocytochemistry studies of BMEC with anti-S fimbria-binding protein antibodies revealed that the 65-

57 f Ecgp, showed 70% sequence homology to an S-fimbria-binding sialoglycoprotein reported earlier.

58 lated, and the glycosylation is required for fimbria biogenesis and bacterial adhesion.

59 ss glycosylated surface adhesin required for fimbria biogenesis and biofilm formation in Streptococcu

60 In the adult fimbria, brevican expression was restricted to astrocyte

61 in fractional anisotropy in the ipsilateral fimbria but not in the contralateral fimbria from p8 to

62 es, dendrites (stratum radiatum), and axons (fimbria), but not astrocytes.

63 e by polymerase chain reaction for adherence fimbria, but 11 strains were positive for EAggEc heat-st

64 ndrocytes and white matter astrocytes in the fimbria, but the expression of brevican in these two gli

65 We have now purified the native minor fimbria by ion-exchange chromatography and sequenced the

66 on-exchange chromatography and sequenced the fimbria by tandem mass spectrometry (MS/MS), confirming

67 n, the major structural subunit of a type-IV fimbria called the bundle-forming pilus (BFP), a prepili

68 us and a secondary germinal matrix, near the fimbria, called the hippocampal subventricular zone (HSV

69 In the marine teleost, sablefish (Anoplopoma fimbria), complementary genomic and genetic studies led

70 pectrometry (GC-MS) confirmed that the minor fimbria contains the DC-SIGN-targeting carbohydrates fuc

71 P(+) oligodendrocytes that migrated into the fimbria, corpus callosum, and cerebral cortex.

72 es using ETEC-expressing colonization factor fimbria CS17 and CS19.

73 ses to both the Shigella vector and the ETEC fimbria CS4.

74 vated cell sorter, but not with noninvasive, fimbria-deficient mutant or purified P. gingivalis antig

75 EC) cultured with wild-type P. gingivalis, a fimbria-deficient mutant, and purified antigens.

76 riated P. gingivalis 381, in contrast to its fimbria-deficient mutant, P. gingivalis DPG3, efficientl

77 DPG3, a P. gingivalis fimbria-deficient mutant, was impaired in its invasion c

78 ve P. gingivalis (strain 381) (10(7) CFU); a fimbria-deficient P. gingivalis; or metronidazole before

79 The fimbria demonstrated a small relation between fringes an

80 can form biofilm on HEp-2 cells in a type 1 fimbria-dependent manner.

81 Monocytes used as controls demonstrated fimbria-dependent uptake of 381 as well but produced low

82 onditioning stimulation of the contralateral fimbria depressed the CA3 synaptic response and left the

83 he adaptive immune responses to a toxoid and fimbria-derived subunit vaccine against ETEC.

84 A mutagenesis, we have characterized a novel fimbria (designated AAF/II) which mediates HEp-2 adheren

85 ection by Escherichia coli expressing the Dr fimbria (Dr(+)).

86 STIC lesions in the fimbria expressed high levels of TGFBI, which was predom

87 To define the connection between P fimbria expression and motility in UPEC, the role of pap

88 ompetence but are apparently not involved in fimbria expression of A. actinomycetemcomitans.

89 ilA or pilBC deletion did not seem to affect fimbria expression or cell surface structure in either r

90 of the invertible element controlling type 1 fimbria expression to phase vary contributes significant

91 MR/P fimbria expression, which correlates with the swimmer ph

92 electron microscopy revealed that the minor fimbria forms fibers approximately 200 nm in length that

93 h factor, can also prevent the loss of these fimbria fornix axotomised cholinergic neurons, where GM1

94 11 and continuing until p28, the ipsilateral fimbria fornix degenerates.

95 Transection of the fimbria fornix leads to retrograde degeneration of axoto

96 migrated into corpus callosum, striatum, and fimbria fornix to differentiate into the NG2-positive no

97 is (cynomolgous) monkeys received unilateral fimbria fornix transections followed by chronic intracra

98 We have lesioned the fimbria fornix, a major pathway of septal cholinergic fi

99 ptum following unilateral transection of the fimbria fornix.

100 cellularis, or unilateral transection of the fimbria fornix.

101 the septum 3 weeks before transection of the fimbria fornix.

102 er-matched controls along the left and right fimbria-fornix (FF), parahippocampal WM bundle (PWMB), a

103 thalamic nuclei (ATN) or transection of the fimbria-fornix (FF).

104 ll animals received a complete lesion of the fimbria-fornix (FF).

105 region (PARA) or electrolytic lesions of the fimbria-fornix (FNX) and were tested for their (a) discr

106 Lesions of the fimbria-fornix disrupt auditory gating by preventing cho

107 Results demonstrate the importance of the fimbria-fornix fiber system in spatial short-term memory

108 pal white matter bundle, and the ipsilateral fimbria-fornix in regions located within the medial temp

109 ast, patterned electrical stimulation of the fimbria-fornix increased TGC in amnestic animals and par

110 control animals 2 weeks following unilateral fimbria-fornix lesion.

111 of trkA (RTA) into the lateral ventricle of fimbria-fornix lesioned animals.

112 pal injections of 192 IgG-saporin (SAP-HPC), fimbria-fornix lesions (FF), or sham control surgeries w

113 ions on hippocampal physiology compared with fimbria-fornix lesions and septal inactivation, we obser

114 y concomitant theta burst stimulation of the fimbria-fornix pathway.

115 Remarkably, artificial hPAC generated by fimbria-fornix stimulation during recall of a learned av

116 Fimbria-fornix transection resulted in a marked loss of

117 Similar to the effects of fimbria-fornix transection, Pb exposure resulted in a lo

118 Fimbria-fornix transections (FFTs), conducted 1 day afte

119 gnocellularis, radiofrequency lesions of the fimbria-fornix, and aspiration lesions of the frontal co

120 From preoperative imaging, the fimbria-fornix, parahippocampal white matter bundle and

121 s have demonstrated that DBS targeted to the fimbria-fornix, the region that appears to regulate hipp

122 toration of auditory gating by DMXB-A in the fimbria-fornix-lesioned rats was blocked by intracerebro

123 DMXB-A restored auditory gating in the fimbria-fornix-lesioned rats, indicating that activation

124 of colchicine-pretreated, control, untreated fimbria-fornix-transected (5 days), as well as perforant

125 ubcortical inputs to the hippocampus via the fimbria-fornix.

126 ore auditory gating following lesions of the fimbria-fornix.

127 (approximately 100 msec duration) evoked by fimbria/fornix (FF) stimulation in a majority of neurons

128 sly, we demonstrated that transection of the fimbria/fornix blocked the excitatory effect of corticot

129 atter regions including the corpus callosum, fimbria/fornix, and cerebellar deep white matter.

130 entorhinal cortices, the corpus callosum and fimbria/fornix, and cerebellar white matter.

131 ased dramatically in the corpus callosum and fimbria/fornix.

132 ections from the ventral hippocampus via the fimbria/fornix.

133 lateral fimbria but not in the contralateral fimbria from p8 to p42.

134 t MrpG, a putative minor subunit of the MR/P fimbria, functions as an adhesin responsible for hemaggl

135 ene cluster kps, and the P (pap) and S (sfa) fimbria gene clusters.

136 nscriptome profiling revealed YjgK represses fimbria genes at 8 h (corroborated by qRT-PCR and a yeas

137 Wild type fimbria genes were replaced both in Salmonella enteritid

138 (FT) and ovaries revealed that normal FT and fimbria had a lower tissue modulus, a measure of stiffne

139 us-nucleus accumbens pathway was found after fimbria high-frequency stimulation in naive animals, str

140 e, corpus callosum, anterior commissure, and fimbria hippocampi, were investigated for structural and

141 aining for myelin basic protein (MBP) at the fimbria hippocampus and the internal capsule areas in th

142 ial adhesin designated aggregative adherence fimbria I (AAF/I), the genes for which have been cloned

143 a caused 20-fold increases in GFAP-IR in the fimbria/IC and 2-fold increases in the hippocampal neuro

144 P-IR in the hippocampal neuropil than in the fimbria/IC and the GFAP-IR remained greatly increased at

145 fold higher in old than in young mice in the fimbria/IC but not appreciably changed in hippocampus.

146 d the fimbrial antigen aggregative adherence fimbria II (AAF/II), all of which are encoded on the 65-

147 and 130 (minor)-kDa sialoglycoproteins by S fimbria immunoblotting and were purified from bovine BME

148 The phase variation of type 1 fimbria in E. coli provides a unique system in which to

149 ls should employ thorough examination of the fimbria, including multiple sections from each tissue bl

150 sed of a mannose-binding lectin domain and a fimbria-incorporating pilin domain.

151 ohesin-1, was shown to mediate P. gingivalis fimbria-induced activation of beta(2) integrin for ICAM-

152 Indeed, treatments that interfered with fimbria-induced activation of CD11b/CD18 (i.e., blockade

153 raft organization, was found to inhibit the fimbria-induced assembly of CD14/TLR2 signaling complexe

154 relatively low within areas of white matter (fimbria, internal capsule) and select neuronal fields (h

155 Type 1 fimbria is a proven virulence factor of uropathogenic Es

156 y the gene locus fimQ-fimP-srtC1, the type 1 fimbria is comprised of the fimbrial shaft FimP and the

157 that the receptor-binding domain of a K88ac fimbria is contained, at least in part, within the antig

158 We further show that the minor fimbria is glycosylated by ProQ staining and that glycos

159 allei is an enteric pathogen and that type 1 fimbria is important for B. pseudomallei intestinal adhe

160 e demonstrated that mannose-sensitive type 1 fimbria is involved in the initial adherence of B. pseud

161 ion of mannose-resistant/Proteus-like (MR/P) fimbria is phase variable because of the inversion of a

162 Expression of the fimbria is regulated at the transcriptional level by a p

163 d to determine how much of the assembled K99 fimbria is required to maintain protective immunity.

164 P5-fimbria is the critical appendage of NTHI that participa

165 The fimbria is the source of nearly one half of PPSCs, sugge

166 ization factor of the class 5 family (CFA/I) fimbria, is highly immunogenic and protects against oral

167 hogenic Escherichia coli expresses a type IV fimbria known as the bundle-forming pilus (BFP) that is

168 ile diarrhoea worldwide, expresses a type IV fimbria known as the bundle-forming pilus that promotes

169 ion or by anterograde degeneration following fimbria lesion.

170 s with a high degree of identity to the Flp (fimbria-like protein) encoded by the first open reading

171 electron microscopy revealed the absence of fimbria-like surface structures on an OxyR-deficient str

172 sed with its fimH deletion mutant and type 1 fimbria locked-off mutant, while they were significantly

173 were significantly increased with its type 1 fimbria locked-on mutant.

174 tutes the tip of a unique form of the type 2 fimbria long known for its role in coaggregation.

175 protein level) to the Salmonella long polar fimbria (LPF) operon.

176 , the transcription of genes responsible for fimbria, LPS, and EPS production, as well as the transla

177 ferent target areas that communicate via the fimbria may be critically involved in CRH-enhanced start

178 rent target areas, which communicate via the fimbria, may be critically involved in CRH-enhanced star

179 Type 1 fimbria-mediated adherence to HEp-2 cells by two strains

180 In clinical settings, blocking of the P5-fimbria-mediated attachment of NTHIF+ by passive or acti

181 lycoprotein showed effective inhibition of S fimbria-mediated binding of E. coli to BMEC.

182 fraction showed significant inhibition of P fimbria-mediated haemagglutination assay of uropathogeni

183 ability to switch off the expression of MR/P fimbria might be important for kidney colonization.

184 Our results, using conditional fimbria mutants of P. gingivalis, show that P. gingivali

185 In the adult fimbria, no brevican expression was observed in oligoden

186 The fimbria of Tbx1 heterozygous mice showed reduced mRNA le

187 m an occult intraepithelial carcinoma in the fimbria of the fallopian tube and involves the ovary sec

188 anti-minor fimbria serum bound to the minor fimbria on the cell surface of the wild-type strain.

189 to be closely related to the long polar (LP) fimbria operon (lpf) of Salmonella enterica serovar Typh

190 This fiber pathway did not enter the fimbria or alveus along the entire distance of the trace

191 ociated with HBMEC were predominantly type 1 fimbria phase-on (i.e., fimbriated) bacteria.

192 ing to and invasion of HBMEC and that type 1 fimbria phase-on E. coli is the major population interac

193 st report on the identification of the minor fimbria produced by P. gingivalis.

194 ar zone, a source of oligodendrocytes in the fimbria, produced fewer oligodendrocytes in vitro.

195 on of mrkJ resulted in an increase in type 3 fimbria production and biofilm formation as a result of

196 n-containing proteins, in controlling type 3 fimbria production and biofilm formation in K. pneumonia

197 sent findings show that the locus for type 1 fimbria production in this strain includes three genes,

198 inding directly to the phase-variable type 1 fimbria promoter, driving its expression.

199 kDa protein that structurally may be a minor fimbria-protein complex and functionally effectuates coa

200 From controls, the alveus, fimbria, pyramidal cell layer, hippocampal sulcus, and g

201 ion-positive women should be assigned to the fimbria rather than the ovary, and future clinical and r

202 nes encode a novel usher/chaperone assembled fimbria regulated by an ON/OFF invertible promoter switc

203 No fimbria-related genes are evident either 5' or 3' to the

204 urrounding ORFs revealed homology with other fimbria-related proteins.

205 The mannose-resistant, Proteus-like (MR/P) fimbria, responsible for mannose-resistant hemagglutinat

206 p50 subunit) was significantly inhibited in fimbria-restimulated cells.

207 ns and thicker myelin in medium axons in the fimbria, resulting in an overall decrease in myelin.

208 the isthmus and 15 presented the ampulla and fimbria segment of the FT.

209 The anti-minor fimbria serum also reacts with the same-molecular-size f

210 ectron microscopy showed that the anti-minor fimbria serum bound to the minor fimbria on the cell sur

211 In immunoblotting analysis, anti-minor fimbria serum reacted with both the 100 degrees C- and t

212 thus supports the assumption that the type 1 fimbria shaft and the FimH adhesin-receptor interaction

213 onditioning stimulation of the contralateral fimbria significantly depressed the CA3 population respo

214 0 kDa were identified by immunoblotting with fimbria-specific antibodies.

215 tive hemagglutination and agglutination with fimbria-specific antiserum.

216 is analysis revealed elevated numbers of K99 fimbria-specific IgA-producing cells in the LP, PP, and

217 the LP, PP, and spleen, whereas elevated K99 fimbria-specific IgG-producing cells were detected only

218 r structural subunit, and srtC1 for a type 1 fimbria-specific sortase involved in the assembly of the

219 Fimbrial polymerization requires the fimbria-specific sortase SrtC1, which catalyzes covalent

220 Thus, SrtC2 is a fimbria-specific sortase that is essential for assembly

221 l GTPases, that Rac1 mediates the ability of fimbria-stimulated monocytes to bind ICAM-1.

222 second from accumbens neurons responsive to fimbria stimulation.

223 The cerebral cortex, septum, diagonal band, fimbria, striatum, hippocampus, hypothalamus, substantia

224 roscopy demonstrated that a mutant of type 1 fimbria structural genes (DeltafimAICDHF) and a ycfR mut

225 real-time PCR (qRT-PCR) revealed that type 1 fimbria structural genes and a gene encoding a putative

226 , mutations in an oxyR homolog and predicted fimbria structural genes were identified.

227 m women with cystitis were tested for type 1 fimbria switch orientation.

228 Results showed that each fimbria switched binding specificity to that of the reci

229 trains harbor genes encoding adhesive type 1 fimbria (T1F).

230 gingivalis, through its 67-kDa Mfa1 (minor) fimbria, targets the C-type lectin receptor DC-SIGN for

231 o epithelial cells is dependent on a type IV fimbria, termed the bundle-forming pilus (BFP).

232 es the bundle-forming pilus (BFP), a type IV fimbria that has been implicated in virulence, autoaggre

233 Expression of an EAF plasmid-encoded type IV fimbria, the bundle-forming pilus (BFP), is associated w

234 ion of brevican in the postnatal hippocampal fimbria to explore the role of the proteoglycan in centr

235 Fimbria transection blocked CRH-enhanced startle almost

236 the adhesin-receptor interaction of a type 1 fimbria varies as a bacterium is affected by a time-depe

237 a and around the Pia mater, corpus callosum, fimbria, ventricles, and blood vessels in sections from

238 ents demonstrated conclusively that the MR/P fimbria was a critical bladder colonization factor of ur

239 Each fimbria was characterized by its capacity to bind partic

240 bodies the force required to unwind a single fimbria was increased several-fold and the extension len

241 in Tbx1 heterozygous mice indicated that the fimbria was the only region with significant myelin alte

242 Volume reductions in the CA1 and fimbria were 44% and 60% smaller than in the CA2-CA3.

243 Two putative adhesins, flagella and F9 fimbria, were upregulated in the cadA mutant, suggestive

244 immunoreactivity was observed throughout the fimbria, with particularly strong immunoreactivity in th