ライフサイエンスコーパス: firing pattern

1 duced and neurons exhibited a more irregular firing pattern.

2 tylcholine receptor antagonists impairs this firing pattern.

3 ed directions causes a grid cell's grid-like firing pattern.

4 ted a multiphasic response shaping the M/TCs firing pattern.

5 ric isocontour levels of each cell's spatial firing pattern.

6 ar retrosplenial cortex showed bidirectional firing patterns.

7 l cells completely reorganized their spatial firing patterns.

8 dynamics beneath similar population average firing patterns.

9 tassium (Kv) channels that regulate temporal firing patterns.

10 proposed to account for place and grid-cell firing patterns.

11 d cells display strikingly symmetric spatial firing patterns.

12 rd a feed-forward mechanism that is coded by firing patterns.

13 rization of neuronal subtypes based on their firing patterns.

14 to regulate membrane excitability and spike firing patterns.

15 signatures associated with distinct in vivo firing patterns.

16 subregions led to different action potential firing patterns.

17 ha-helix mutations change genome-wide origin firing patterns.

18 omputation of location that drives grid cell firing patterns.

19 replaced by low-entropy, stimulus-entrained firing patterns.

20 odulation of theta rhythmicity and grid cell firing patterns.

21 anglion cells in the two strains had similar firing patterns.

22 urons and in the temporal structure of their firing patterns.

23 uced changes in the preexisting goal-related firing patterns.

24 al ganglia movement disorders by normalizing firing patterns.

25 y, act primarily by eliminating pathological firing patterns.

26 intensities, showed irregular or stuttering firing patterns.

27 differences in dendritic tree morphology and firing patterns.

28 l firing patterns but did not affect spatial firing patterns.

29 mark when hippocampal neurons replay waking firing patterns.

30 glutamatergic stellate cells with sustained firing patterns.

31 shaping action potential (AP) waveforms and firing patterns.

32 e to the temporal nature of action potential firing patterns.

33 by mossy fiber inputs with a wide variety of firing patterns.

34 rons display considerable diversity in their firing patterns.

35 uspected heterogeneity and adaptivity in MEC firing patterns.

36 lls could be distinguished based on neuronal firing patterns.

37 ing did not always necessitate modulation in firing patterns (2/12 cells in globus pallidus; 13/23 ce

38 rhinal cortex, which exhibit spatially tuned firing patterns [2, 3].

39 1) retrograde signaling initiated by in vivo firing pattern, (2) interneuron bAPs detected with fast

40 urons, exhibit tremendous diversity in their firing patterns, a consequence of the complex collection

41 is large, with minimal recurrence of spatial firing patterns across environments.

42 nge between behaviors in the coordination of firing patterns across neurons that could account for th

43 majority of neurons ( approximately 90%) the firing patterns across the four tasks could be explained

44 espondingly, we studied the evolution of the firing patterns along the loop.

45 t cholinergically-induced changes in network firing patterns alter overall network synaptic potentiat

46 Moreover, 5-HT induced spatiotemporal firing pattern alterations could be monitored in neuron

47 spontaneously active, exhibiting a range of firing patterns, although only a minority (15%) exhibite

48 adoxical brain state displaying asynchronous firing pattern and high EMG activity was found unexpecte

49 d potentiation was independent of a specific firing pattern and was not accompanied by increased spik

50 nteract in a highly nonlinear way to produce firing patterns and (2) across animals there is substant

51 itive to noise and stochasticity in neuronal firing patterns and assembly heterogeneity.

52 The link established between rhythmic firing patterns and complex attractor dynamics has impli

53 um channels, but how they combine to control firing patterns and conduction is not well understood.

54 ensors, we evaluated the effects of specific firing patterns and frequencies on activity-dependent so

55 rats, finding two classes of cells based on firing patterns and juxtacellular labeling (of a subset)

56 e extent to which it will determine neuronal firing patterns and network activity remains poorly unde

57 erations in axonal signaling affect neuronal firing patterns and neurotransmitter release, this is an

58 the basal ganglia, including both pathologic firing patterns and normal, task-related modulations in

59 of this hypothesis and discuss how specific firing patterns and oscillatory dynamics in the entorhin

60 However, the relationship between RSC firing patterns and spatial memory remains largely unexp

61 for the temporal organization of hippocampal firing patterns and suggest that cognitive functions tha

62 As a result, LLH alters GC firing patterns and the responses to concomitant excitat

63 ransmitter release, conduction velocity, and firing patterns and understanding the role of particular

64 They differ in their connectivity and firing patterns and, therefore, in their functional prop

65 nal populations defined as type I (irregular firing patterns) and type II (quiescent).

66 ls and influences action potential waveform, firing pattern, and rate.

67 ad that motor disorders derive from abnormal firing patterns, and have led to the hypothesis that sur

68 ring patterns, monitor the transition of the firing patterns, and identify neural synchronization sta

69 afterhyperpolarization, in the regulation of firing patterns, and in setting and stabilizing the rest

70 that include increased firing rate, altered firing patterns, and increased oscillatory activity.

71 trial variations in mean spike rate or burst-firing patterns, and potentially provides a principled f

72 ium currents, and tonic- or initial bursting firing patterns, and received weak excitatory synaptic i

73 ibitory currents are potent in modifying the firing patterns, and the inhibitory response to sound of

74 Overall, these studies reveal novel firing-pattern- and neural-circuit-specific mechanisms o

75 Temporally synchronized neural firing patterns are advantageous for efficiently represe

76 ransmitted to downstream neurons, persistent firing patterns are affected by prior experience in sele

77 e show that contrasting, behaviour-dependent firing patterns are an emergent property of the LC that

78 Behaviorally adequate neuronal firing patterns are critically dependent on the specific

79 Instead, we propose that place cell spatial firing patterns are determined by environmental sensory

80 Neuronal firing patterns are established by the collective activi

81 g of hippocampal neurons, but which specific firing patterns are induced by either of the two process

82 We find that grid cell firing patterns are largely absent in rTg4510 mice, whil

83 However, in vitro firing patterns are not as regular as those in vivo Here

84 In this view, grid and place cell firing patterns are not successive stages of a processin

85 nisms by which experience-related persistent firing patterns are regulated in specific neuronal popul

86 ational lesion," whereby pathologic neuronal firing patterns are replaced by low-entropy, stimulus-en

87 These models assume that grid-like firing patterns are the result of computation of locatio

88 n in neuroscience is to understand how noisy firing patterns are used to transmit information.

89 LINCs display regular spiking non-pyramidal firing patterns, are primarily located in the stratum or

90 where we could definitively identify neural firing patterns as output-null or output-potent.

91 Here, we examined hippocampal neuronal firing patterns as rats ran in place on a treadmill, thu

92 band of Broca (MSDB)-dependent MEC grid-cell firing patterns as the neurophysiological substrate of p

93 tC neurons had preinspiratory or inspiratory firing patterns associated with excitatory effects on bu

94 C neurons had inspiratory or postinspiratory firing patterns associated with excitatory responses on

95 odulin activation specifically during neuron-firing patterns associated with induction of spike timin

96 implemented objective protocols to classify firing patterns based on 5 transients (delay, adapting s

97 sion of motor neuron identity, virtually all firing patterns became distinctly flexor like.

98 After the rats reached peak performance, RSC firing patterns began to represent the upcoming goal loc

99 ciations represented by hippocampal neuronal firing patterns but did not affect spatial firing patter

100 A depolarizing 'leak' current supports this firing pattern, but its molecular basis remains poorly u

101 that shapes action potentials and regulates firing patterns, but is not involved directly in trigger

102 e firing rate determined the ATP cost across firing patterns by controlling the overall number of spi

103 We show how such firing patterns can arise from quite small shifts in the

104 dely held assumption that cell-type-specific firing patterns can be achieved via a vast combination o

105 more show that other aspects of the observed firing patterns can be explained by learning that occurs

106 Moreover, these firing patterns can repeat across similar subsegments of

107 Significant firing pattern changes were observed more frequently in

108 ssary to achieve the high-frequency bursting firing pattern characteristic of both types of LNvs in f

109 developed into mature neurons and exhibited firing patterns characteristic of subpopulations of cort

110 Abnormal neuronal firing patterns characteristic of the fast deactivation

111 AC demonstrated significant changes in EEG firing patterns characterize within explanatory (p < 0.0

112 PMC neurons had homogeneous firing patterns, characterized by tonic activity and pha

113 kinematics over the ten-week period suggests firing patterns collected with the microchannel electrod

114 e-trial population spike trains into spatial firing patterns (combinations of neurons firing together

115 n to the ascending auditory nuclei, the IHCs firing pattern controlled by the alpha9alpha10 receptor

116 signal to hippocampus, and changes in their firing pattern could thus generate a distinct spatial co

117 ral tegmental area (VTA) where they regulate firing patterns critical for movement control, reward, a

118 is currently unknown whether these temporal firing patterns critically rely on upstream cortical inp

119 Furthermore, neural firing pattern decoders outperformed two-channel model d

120 central pattern generators generate similar firing patterns despite several-fold increases in size b

121 llidus; 13/23 cells in VLo), and regularized firing patterns did not always correspond to altered res

122 recorded simultaneously, place and grid cell firing patterns differentially reflect environmental inf

123 GABAA conductance transforms the interneuron firing pattern driven by individual EPSPs into a more re

124 atory neurons generate a unique and reliable firing pattern during sensory stimulation and that this

125 he level of single neurons induced by normal firing patterns during free behavior.

126 Individual LRNs showed several distinct firing patterns during immobility and locomotion, formin

127 nce of the LFP, the organization of neuronal firing patterns during spindles bears little resemblance

128 coordinated replay of prior learning-related firing patterns during subsequent NREM sleep.

129 ippocampal firing during HC-SWRs to cortical firing-patterns during upstates and spindles.

130 istical summaries properly characterized the firing patterns (e. g. template and variability) and qua

131 lts in a significant disruption of grid cell firing patterns, even when the quality of the directiona

132 t of a particular action potential waveform, firing pattern evoked, or a more pronounced spiked broad

133 on information influences spatially-specific firing patterns exhibited by hippocampal neurons.

134 ng spike patterns, and retrieved informative firing patterns expressed by the same population in resp

135 tion and velocity, displaying a tonic-phasic firing pattern for different types of eye movement (sacc

136 owever, with prolonged experience, grid cell firing patterns formed a single, continuous representati

137 supporting a diversity of multineuron spike firing patterns from overlapping sets of neurons.

138 selective modulation of SPNs based on their firing patterns; FSIs inhibit most SPNs but paradoxicall

139 hannelrhodopsin-2, enable precise control of firing patterns; green fluorescent protein-based reporte

140 ns if they have I (KL) and with more regular firing patterns if they do not.

141 noise-like current injections with irregular-firing patterns if they have I (KL) and with more regula

142 allidus, (2) a monophasic stimulus-entrained firing pattern in motor thalamus, and (3) a complete or

143 mediate spontaneous activity and changes of firing pattern in these neurons is essential for underst

144 How do firing patterns in a cortical circuit change when inhibi

145 teracts with the switching between different firing patterns in a state-dependent and type-dependent

146 provides an accurate readout of the evolving firing patterns in both types of interneuron.

147 To elucidate the origin of firing patterns in branched mechanoreceptors, we combine

148 associative learning, that the coherence of firing patterns in directly connected entorhinal-hippoca

149 ntially affected, such that action potential firing patterns in dorsal mEC-SCs were altered, while th

150 ) GP-DBS resulted in: (1) stimulus-entrained firing patterns in globus pallidus, (2) a monophasic sti

151 shift from phasic to tonic action potential firing patterns in KO neurons.

152 de and that maintain their vocalization-like firing patterns in levels of background sound that permi

153 computational study proposed that population-firing patterns in parietal cortex have one-dimensional

154 in a key cortical area adapt their intrinsic firing patterns in response to the acoustic environment.

155 action regulates the emergence of persistent firing patterns in specific neuronal populations.

156 Here we compare conductance and firing patterns in spinal motoneurons during network act

157 ronal excitability, transmitter release, and firing patterns in thalamic networks, thereby altering t

158 stems from increasing the regularity of the firing patterns in the basal ganglia (BG).

159 on a microscopic scale, in relation to their firing patterns in the environment would facilitate a gr

160 , InSyn1 null mice exhibit elevated neuronal firing patterns in the hippocampus and deficits in fear

161 d with increased synchronization of neuronal firing patterns in the hippocampus and the connected ven

162 iophysical implementation of dopamine neuron firing patterns in the intact brain.

163 espondingly, we studied the evolution of the firing patterns in the loop.

164 approach responses are represented in neural firing patterns in the major output structure of the mes

165 In the recordings, we found distinct firing patterns in the striatum, globus pallidus, and su

166 : The capability to disentangle superimposed firing patterns in upstream networks, and to represent t

167 regulation of their AP shape during natural firing patterns in vivo.

168 sive stimuli exposure produced heterogeneous firing patterns in VTA-projecting BNST neurons.

169 approach flexibly uncovers diverse dynamical firing patterns, including pulsatile responses to behavi

170 The IS vs. CA firing pattern is determined by expression of KCNQ chann

171 Understanding this shared variability in firing patterns is critical for appreciating the represe

172 lts suggest that the observed differences in firing patterns likely reflect dissimilarities in task a

173 These differences in firing patterns may be due to variations in behavioral c

174 ferent activity can partly close I (KL), VGN firing patterns may become more receptive to extrinsic c

175 Identification of specific firing patterns may help determine targets and patient-s

176 The in vivo firing pattern modulated the size of unitary EPSPs impin

177 tem is successfully used to recognize neural firing patterns, monitor the transition of the firing pa

178 ferior colliculus (IC), the diverse temporal firing patterns must be coded by other synaptic mechanis

179 rovide a comprehensive overview of resulting firing patterns, network connectivity, signal directiona

180 nto the diversity of muscle spindle afferent firing patterns observed experimentally, particularly in

181 This is at odds with firing patterns observed in the cortex of intact animals

182 In females, estradiol shifts the firing pattern of AVPV/PeN Kiss1 neurons and alters cell

183 nd how tonic GABAA conductance regulates the firing pattern of CA3 interneurons.

184 Furthermore, this plasticity altered the firing pattern of CINs increasing the variance of action

185 out the ion channel machinery that specifies firing pattern of enteric neurons.

186 The spatial firing pattern of entorhinal grid cells may be important

187 The firing pattern of midbrain dopamine (DA) neurons is well

188 Moreover, although a distinct firing pattern of Mthal neurons, called low-threshold ca

189 s can be accompanied by rapid changes in the firing pattern of neural networks.

190 ed in neonates or infants, we focused on the firing pattern of neurons in visual area V2, the earlies

191 (ChR2) in brain tissue, and consequently the firing pattern of neurons, by manipulating the phase of

192 tions and the rapid formation of the spatial firing pattern of place cells.

193 Purkinje neurons have a complex firing pattern of regular spikes interrupted by intermit

194 tractor corresponding to a different spatial firing pattern of sparks.

195 han excitability, as stimulation altered the firing pattern of STN spiking without changing overall r

196 the mechanism considered here (the change in firing pattern of subthalamic neurons through the dopami

197 and are glutamatergic; able to modulate the firing pattern of the mitral cells (M/TCs).

198 These "attract" the firing pattern of the network to a stored pattern, even

199 nd inhibitory synaptic currents to shape the firing pattern of the neuron.

200 aptic plasticity that regulates the temporal firing pattern of the principal output cells of the cere

201 inesia is causatively regulated by the burst-firing pattern of the subthalamic nucleus (STN) in a fee

202 The observed firing patterns of CA3 meet these criteria and can be qu

203 ostsynaptic cholinergic receptors encode the firing patterns of CHIs in the striatum.

204 tures of sensory scenes to be encoded in the firing patterns of cortical populations.

205 shapes sensory representations, we measured firing patterns of defined types of neurons in the barre

206 Our results show that firing patterns of densely perturbed oscillators cannot

207 light stimulation method for modulating the firing patterns of electrically-excitable cells using su

208 oidal boundary geometry distorts the regular firing patterns of entorhinal grid cells, proposedly pro

209 rdcastle et al. (2015) show that the spatial firing patterns of grid cells accumulate error, drifting

210 The firing patterns of grid cells in medial entorhinal corte

211 The periodic spatial firing patterns of grid cells in the hippocampal formati

212 sory input in generating the regular spatial firing patterns of grid cells, and changes in grid cell

213 not considered evoking long-term changes in firing patterns of in-vitro networks by introducing trai

214 We show that standard spatial and temporal firing patterns of individual hippocampal principal neur

215 as typically applied to humans, affects the firing patterns of individual neurons in alert nonhuman

216 atory activity interacting strongly with the firing patterns of inhibitory neurons, suggesting a proc

217 The firing patterns of interneurons developed a relationship

218 ng algorithms have been used to identify the firing patterns of isolated neurons ('single units') fro

219 ets, we examined the impact of SPW-Rs on the firing patterns of lateral septal (LS) neurons in behavi

220 ell-type identification, to characterize the firing patterns of monosynaptic inputs to dopamine neuro

221 es high-frequency action potentials, but the firing patterns of most peptide/GABA-releasing interneur

222 ntributions to schema updating by monitoring firing patterns of multiple CA1 neurons as rats learned

223 The firing patterns of neurons in the globus pallidus (GP) a

224 This work indicates that the spatial firing patterns of neurons in the medial entorhinal cort

225 ed calcium channel inhibitors on synchronous firing patterns of our hiPSC-derived neural networks.

226 erneurons play critical roles in shaping the firing patterns of principal neurons in many brain syste

227 Although the firing patterns of principal neurons in the olfactory bu

228 is unknown how this translates to different firing patterns of projection-defined DA subpopulations

229 that Rac1 modulates SK channel activity and firing patterns of Purkinje cells.

230 We used phase resetting methods to predict firing patterns of rat subthalamic nucleus (STN) neurons

231 mulating and inhibiting the action potential firing patterns of SH-SY5Y human neuroblastoma cells and

232 cal and chemical stimulation showed specific firing patterns of spike frequency adaptation, postinhib

233 iginates in the circuitry that regulates the firing patterns of spinal motorneurons.

234 We show how the changes in firing patterns of STN neuron due to the lack of dopamin

235 e spike threshold, filtering properties, and firing patterns of the different motoneuron pools are gr

236 Percepts in our model are identified in the firing patterns of the neuronal units.

237 When comparing the firing patterns of the same neurons across brain states

238 combined with self-motion information in the firing patterns of these cells.

239 potentials that are critical to shaping the firing patterns of these cells.

240 However, this system is complex because firing patterns of these neurons are heterogeneous; subp

241 most cases, the distribution and dynamics of firing patterns of these neurons during behavior are not

242 tactile information, the highly reproducible firing patterns of these neurons suggest that a single s

243 The in vivo firing patterns of ventral midbrain dopamine neurons are

244 In contrast, the heterogeneous firing patterns of VPvm neurons may implicate VPvm in fa

245 e model that predicts the dependence of IHCs firing patterns on the level of activation of two parame

246 monstrate distinct, synchronized spontaneous firing patterns only in animals that develop tinnitus, d

247 h switch, but did not develop anticorrelated firing patterns or predict choice accuracy.

248 ce, based solely on the neurons' fluctuating firing patterns, or it may occur too frequently to be ex

249 oordinate channel expression to uphold their firing patterns over long timescales [1, 5]?

250 The firing pattern parameters, experimental conditions, spik

251 does not interfere with the action potential firing pattern, pharmacological ablation of the alpha9al

252 led 9 unique (plus one spurious) families of firing pattern phenotypes while distinguishing potential

253 s are necessary for generating grid-specific firing patterns, possibly by driving velocity modulation

254 Place cell firing patterns predominantly reflect visual inputs, whi

255 We found that the "in vivo firing pattern" produced a transient firing-induced supp

256 To investigate whether spatial firing patterns recur when animals are exposed to multip

257 We found neurons whose firing patterns reflected the presence of walls and drop

258 events that cause changes in dopamine neuron firing patterns remain unknown.

259 cified neurons had synaptic properties and a firing pattern reminiscent of a pyramidal cell-like phen

260 In rodents, waking firing patterns replay in NREM sleep during hippocampal

261 l, on the replay of spatially tuned neuronal firing patterns representing discrete places and spatial

262 Moment-to-moment tracking of neural ensemble firing patterns revealed that the prelimbic network acti

263 provide inputs to the hippocampus, and their firing patterns shift relative to each other across diff

264 channels increases the variability in their firing pattern, sometimes also increasing the number of

265 neurons encode both modalities with similar firing patterns (stimulus-synchronized or nonsynchronize

266 ations of neurons firing together), temporal firing patterns (temporal activation of these groups of

267 with female athletes progressing to a slower firing pattern that was not observed in males.

268 perirhinal cortex of rats generate sustained firing patterns that discriminate large segments of the

269 al cortex exhibit remarkably regular spatial firing patterns that tessellate all environments visited

270 ous T-maze alternation task and examined RSC firing patterns throughout learning.

271 However, accumulating phase noise causes the firing pattern to drift and become corrupted.

272 Using these firing patterns to generate realistic inputs to our netw

273 s repetitive firing, and can convert regular firing patterns to irregular ones.

274 rate and universal metric requires grid cell firing patterns to uniformly cover the space to be navig

275 Therefore, 'drift' in neural firing patterns, typically construed as disruptive 'inst

276 ers of Na(+) and K(+) channels, are similar, firing patterns vary among cell types.

277 uced a shorter NIP, and this altered network firing pattern was normalized by clonazepam, a positive

278 tropy, a measure of the diversity of network firing patterns, was lower in the dorsal CA1 region in t

279 Neuronal firing patterns were analysed by constructing hazard fun

280 es to the multicompartment environment, grid firing patterns were dominated by local environmental cu

281 In contrast, VPvm firing patterns were heterogeneous, changing FRs during

282 Counter to expectation, in vitro firing patterns were less diverse, more transient-spikin

283 this finding, both regular-spiking and burst firing patterns were profoundly depressed in the mouse w

284 However, the distinct burst firing patterns were related to functional differences:

285 Their firing patterns were stable across multiple sleep-wake c

286 However, grid cell firing patterns were unaffected, concordant with an abse

287 atial cells and confirmed that their spatial firing patterns were unrelated to running speed and high

288 The calyx showed a characteristic burst firing pattern, which has previously been shown to origi

289 term alterations in medial rectus motoneuron firing pattern, which were more drastic in MLF of animal

290 bushy cells exhibit hyperacusis-like neural firing patterns, which are comprised of enhanced sound-d

291 reorganization of the postsaccadic neuronal firing patterns, which follow a similar retinotopic prog

292 from an initial burst to a more distributed firing pattern, while having no impact on overall action

293 ze of the AIS likely underlie differences in firing pattern, while the tapering diameter of AIS may d

294 -field environment, where grid cells exhibit firing patterns with a 6-fold rotational symmetry [5, 6]

295 exhibit considerable heterogeneity in their firing patterns with both similarities and differences t

296 one would like to combine precise control of firing patterns with highly sensitive probes of cellular

297 3 neurons discharged in spatially irregular firing patterns, with weak theta-modulation and head-dir

298 nimals would reveal dynamic shifts in neural firing patterns within and across sensory, sensorimotor,

299 have been linked to abnormal and hyperactive firing patterns within the auditory system, these result

300 rates of transgenic neurons are reduced, and firing patterns within Up states are altered, with longe