1 nge (1400 mg protein in DBPCFC) at 6 months (
first phase).
2 ses 2-4 decreased to 35%, 12%, and 7% of the
first phase.
3 e active and control group at the end of the
first phase.
4 econd phase that was half the voltage of the
first phase.
5 as incrementally increased above that of the
first phase.
6 f the tool, which was modified following the
first phase.
7 +/- 0.1 microM, reversing the effect of the
first phase.
8 ction of the most probable isotopologue in a
first phase.
9 We conducted the
first phase 0 clinical trial in oncology of a therapeuti
10 roup and none of the control group after the
first phase (
0 of 46; 95% CI 0-9; p<0.001).
11 Analysis of secretion kinetics identified a
first phase (
0-2 min) mediated by VAMP2 and second (2-10
12 In the
first phase (
0-20 min), p300 is recruited to ERalpha by
13 t research organization were enrolled in the
first phase 1 clinical trial of TGN1412, a novel superag
14 Vaccine Research Center (VRC) 004 is the
first phase 1 dose-escalation study of a multiclade HIV-
15 The brains of all 8 patients in the
first phase 1 ex vivo trial and of 2 patients in a subse
16 d immunogenicity of a WNV DNA vaccine in its
first phase 1 human study.
17 stically with chemotherapy, we conducted the
first phase 1 study of intraventricular immunochemothera
18 Since the publication of the
first phase 1 trials of bortezomib 10 years ago, this fi
19 This
first phase 1/2 trial testing bendamustine, lenalidomide
20 A triphasic decline consists of a
first phase (
1-2 days) with rapid virus load decline, fo
21 The reform's
first phase (
2009-11) emphasised expanding social health
22 ed investigational new drug approval for the
first phase 2A clinical trial of ischaemia-tolerant mese
23 lood, Gill et al describe the results of the
first phase 3 clinical trial evaluating recombinant von
24 This study is the
first phase 3 randomised trial recruiting only Asian pat
25 single-arm, prospective cohort trial is the
first phase 3 safety study to describe outcomes in child
26 We report results of the
first phase 3 trial assessing long-acting intramuscular
27 Early data emerging from the
first phase 3 trial of a malaria vaccine are raising hop
28 In the
first phase,
363 scientists scored 480 applications.
29 The
first phase,
a flickering stepwise transition from a low
30 In the
first phase,
a single treatment was provided (intraperit
31 In the
first phase,
a solid liquid extraction procedure was opt
32 In the
first phase,
a survey was conducted using multistage clu
33 In the
first phase,
an apical actomyosin network is formed.
34 dy included 294 patients in 5 centers in the
first phase and 65 patients in 3 centers in the second p
35 While three mutants had a shorter
first phase and a longer second phase than the wild-type
36 orofacial stereotypies, TP/R emerges in the
first phase and vanishes prior to the second.
37 ear waveforms had 4-, 8-, and 16-millisecond
first phases and a 3.5-millisecond rectilinear second ph
38 The exponential biphasic waveform had a 60%
first-phase and a 50% second-phase tilt.
39 and insulin regulation, including diminished
first-phase and accentuated peak insulin secretion in re
40 lation, with a rapid (minutes) and transient
first phase,
and a slow and sustained (24-72 hours) seco
41 six (9-15 years) at home in a reconnaissance
first phase,
and nine (5-14 years) in hospital in phase
42 Despite rapid antibody declines in the
first phase,
antibodies in the second phase persisted at
43 The
first phase ("
baseline") offered no rewards.
44 cant active hemodynamic response in only the
first phase,
before the pain.
45 , 3 descending-ramp waveforms, 3 rectilinear
first-phase biphasic waveforms, a Gurvich waveform, and
46 trite scavenger uric acid did not affect the
first phase but ameliorated the second phase of endothel
47 In the
first phase,
Ca2+ bound to the C-ter EF hand pair in CaM
48 In the
first phase,
CD8+ cells remain sequestered within the ly
49 In the
first phase,
chains are synthesized in a unidirectional
50 In the
first phase,
children learn small exact number word mean
51 The
first phase,
common to all RINs, is bipolar migration di
52 The
first phase,
completed in 2012, profiled the transcripto
53 In the
first phase,
consenting women aged 25-64 years presentin
54 The
first phase,
corresponding to prenatal development, is c
55 As a result, only the
first-phase data were used in additional analyses.
56 AL-containing ART, with a longer duration of
first-phase decay consistent with RAL-mediated blockade
57 ffectiveness of therapy, whereas the rate of
first phase decline depends on multiple parameters inclu
58 ibavirin-particularly those with an adequate
first-phase decrease (0.61 vs 0.35 log10 IU/mL/week; P =
59 The
first-phase decrease in HCV RNA was similar between grou
60 ce was greatest in patients with an adequate
first-phase decrease in HCV RNA.
61 NK cells correlated with treatment-induced,
first-phase decreases in viral load (P<.05) and remained
62 on could be mainly energetically driven; the
first phase deposited is hydrated ACC, which then conver
63 olar NEFO was a damped sine wave with 140 ns
first phase duration at 50% height; the peak amplitude o
64 In the
first phase during concentration of Gag3 into foci, intr
65 ulsatility of individual islets enhances the
first-phase elevation and second-phase pulses of insulin
66 In the
first phase,
Elimination, transformed cells are destroye
67 The
first phase,
elucidation of the renin-angiotensin-aldost
68 and easy phase change material and mark the
first phase engineering in anisotropic van der Waals (vd
69 At the single L-cell level,
first-phase forskolin-induced exocytosis was reduced to
70 The
first phase generates pre-sacral structures (the so-call
71 We report the findings from the
first-phase genetic analyses in 1,227 participants from
72 XPR1 knockdown slightly blunted
first-phase glucose-stimulated insulin secretion in MIN6
73 in type 2 diabetes, islets exhibit decreased
first-phase glucose-stimulated insulin secretion, impair
74 The increased
first-phase glucose-stimulated release of insulin observ
75 ed predocked SG fusion accounted for reduced
first-phase GSIS, selective reduction of exocytosis of s
76 ntactic chain in rigid serial order once the
first phase has begun.
77 First-phase HCV decline (baseline/treatment day 4) was s
78 lls from patients with a less than 2 log(10)
first-phase HCV RNA decline exhibited lower pSTAT1 induc
79 from patients with a greater than 2 log(10)
first-phase HCV RNA decline to IFN-alpha-based therapy (
80 We now report results from the
first phase II clinical trial developed exclusively for
81 This is the
first phase II enzymatic product identified that can sig
82 CONCLUSION This is the
first phase II study of a new agent in sarcoma to includ
83 We report, to our knowledge, the
first phase II trial of pomalidomide administered in com
84 of systemic therapies and the results of the
first phase III clinical trial evaluating the addition o
85 The E1496 study provides the
first phase III data in untreated indolent lymphoma that
86 n Therapy Oncology Group (RTOG) 8610 was the
first phase III randomized trial to evaluate neoadjuvant
87 This
first phase III study on a topical inhibitor of corneal
88 ith 2 or more controller medications, in the
first phase III trial of tiotropium in children with sev
89 Results of the
first phase III trial of VEGF-targeted therapy (sorafeni
90 multicenter study, to our knowledge, is the
first phase III trial to compare trabectedin versus daca
91 To our knowledge, this is the
first phase III trial to perform prospective analysis of
92 To our knowledge, V325 is the
first phase III trial to report clinical benefit in AGGE
93 f Preterm Infants: The Pre-B Project" is the
first phase in a process to present the current state of
94 ay of Class I messages and the length of the
first phase in decay of Class II messages.
95 During the
first phase,
in which NF-kappaB signaling is dispensable
96 The
first phase included 1-hour qualitative telephone interv
97 We propose that the
first phase,
including a stepwise reduction in stiffness
98 st nNOS-2 had an opposing effect against the
first phase,
increasing its intensity.
99 ays a biphasic pattern of expression, with a
first phase independent of Rme1 function and dependent o
100 hases, requiring ATM and NEMO/IKK-gamma: The
first phase induced TNF-alpha-TNFR1 feedforward signalin
101 n murine pancreatic islets leads to impaired
first phase insulin release ex and in vivo.
102 ncrease with oral glucose suggesting loss of
first phase insulin release.
103 in 4-mediated granule pre-docking to support
first-phase insulin exocytosis.
104 that PI4P5Kalpha(-/-) mice exhibit increased
first-phase insulin release and improved glucose clearan
105 The main study group (n = 389) had
first-phase insulin release on an intravenous glucose to
106 file as the main study group except they had
first-phase insulin release that was lower than the thre
107 = 3) had different autoantibody profiles and
first-phase insulin release threshold combinations.
108 -1 elicited significant potentiation of only
first-phase insulin release.
109 We studied the change in the
first-phase insulin response (FPIR) during the progressi
110 A declining
first-phase insulin response (FPIR) is associated with p
111 Primary endpoints were change in
first-phase insulin response and insulin sensitivity as
112 First-phase insulin responses (FPIRs) during the intrape
113 2.8 mg . min(-1), respectively; P = 0.9) or
first-phase insulin secretion (-21 +/- 212 compared with
114 First-phase insulin secretion (0-10 min) increased by 70
115 U . L; P < 0.05) with compensatory increased
first-phase insulin secretion (56.1 +/- 8.5 vs. 25.3 +/-
116 rance test and meal tolerance test to derive
first-phase insulin secretion (FPIR), insulin sensitivit
117 ice demonstrated that this compound restored
first-phase insulin secretion and enhanced pancreatic be
118 ng alleles were associated with a measure of
first-phase insulin secretion at P < 0.05 and provided n
119 n factor, was strongly associated with lower
first-phase insulin secretion but has no evidence for an
120 First-phase insulin secretion decreased across NGT categ
121 From our model analysis we note that
first-phase insulin secretion depends on rapid depletion
122 he OGTT together with the restoration of the
first-phase insulin secretion in diabetic subjects might
123 nt starch intake significantly increased the
first-phase insulin secretion in individuals at risk of
124 Loss of
first-phase insulin secretion is an early sign of develo
125 t increased beta-cell apoptosis and impaired
first-phase insulin secretion precede the development of
126 ut T2D, identifies the mechanisms modulating
first-phase insulin secretion rate in response to basal
127 In adult NG2KO mice,
first-phase insulin secretion was lost, and these glucos
128 the prevailing level of insulin resistance,
first-phase insulin secretion was markedly decreased in
129 The
first-phase insulin secretion was restored in type 2 dia
130 ng of the data showed significantly improved
first-phase insulin secretion with resistant starch.
131 espectively), and glucose disposition index (
first-phase insulin secretion x insulin sensitivity).
132 the largest genome-wide association study of
first-phase insulin secretion, as measured by intravenou
133 First-phase insulin secretion, glucose potentiation of a
134 test (OGTT), a frequently used surrogate of
first-phase insulin secretion, was not associated with t
135 n, while effects on granule docking affected
first-phase insulin secretion.
136 imulation, which is reflected in potentiated
first-phase insulin secretion.
137 insulin pulse amplitudes and a reduction in
first-phase insulin secretion.
138 lated as ATIS: (1/GlyRa x fasting insulin) x
first-phase insulin secretion.
139 sampled intravenous glucose tolerance test (
first-phase insulin secretion; acute insulin response [A
140 ion displays a biphasic profile in which the
first phase involves a fast sulfur transfer reaction fro
141 The
first phase involves producing a description of the syst
142 can be portrayed as a two-phase process: The
first phase involves the physical translocation of a can
143 In the
first phase,
involving 252 subjects, at 4 months, there
144 The
first phase is a parasitism phase where the nematode est
145 The
first phase is abolished as OmpC becomes more stable at
146 The
first phase is also accompanied by the generation of a c
147 The
first phase is considered the early phase of the acciden
148 The
first phase is defined by nonspecific medial and adventi
149 The
first phase is due to the presence of a Rac2-PLD2 positi
150 The
first phase is marked by large transcriptome changes as
151 phase, we feel that an understanding of the
first phase is now within sight, due in part to a better
152 The
first phase is rapid, induces low-level production of MC
153 The
first phase is redistribution of the resonance species t
154 The
first phase is related predominantly to the reach locati
155 The
first phase is restored by expression of mutant cofilin-
156 The rate of the
first phase is second order in hydroxide ion, while that
157 compact UHS, which works in two phases: The
first phase is solved optimally, and for the second we p
158 The
first phase is then rapidly displaced in the primary cha
159 nd paw induces a biphasic pain response; the
first phase is thought to result from direct activation
160 The
first phase is triggered by rapid light-induced changes
161 The
first phase is triggered via the TLR4 on hematopoietic c
162 ghting its role as an important amplifier of
first-phase ISR in T2DM.
163 particular, the responsiveness to glucose in
first-phase ISR is blunted.
164 gmented both first- and second-phase ISR but
first-phase ISR more in T2DM subjects (approximately eig
165 In the
first phase,
it identifies small candidate subtrees from
166 second phase of PI3K activation requires the
first phase;
it is this second phase that is augmented b
167 In the
first phase,
L. donovani promastigotes induce activation
168 Unless this
first phase lasted only 40 ms, this primacy effect persi
169 declined in a biphasic manner, where a rapid
first phase lasting for 25 days (IQR: 23-58) was followe
170 The
first phase,
MAPP I, included >1,000 participants who co
171 harply different in these two phases; in the
first phase,
MDMX depletion was synergistic with DNA dam
172 In the
first phase,
membrane proteins from the budding yeast Sa
173 those with electric light at home (n = 97 in
first phase;
n = 17 in second phase).
174 se living without electric light (n = 243 in
first phase;
n = 25 in second phase) to those with elect
175 1 activates ERK1/2 in a biphasic manner: the
first phase occurs in response to StxB1 subunit, while t
176 Typically, the
first phase of a genome wide association study (GWAS) in
177 The data generated here comprise the
first phase of a genome-wide association analysis in pat
178 or Americans--the B-24 Project." This is the
first phase of a larger project designed to develop diet
179 They are dispensable for the
first phase of A13 development but are required for the
180 assessed the population-level effect of the
first phase of Avahan (2003-08).
181 model of PGC DNA demethylation in which the
first phase of comprehensive 5mC loss does not involve 5
182 ses eye rotation during acceleration and the
first phase of deceleration.
183 We designated the
first phase of dissemination "adherence-mediated migrati
184 hen activity of this pathway is reduced, the
first phase of elongation growth is absent, and this is
185 The
first phase of extinction was coincident with a slow inj
186 The
first phase of genome-wide association studies (GWAS) as
187 During a
first phase of glycosylation, the conformation of GtfB i
188 nsistently, STING was necessary to mount the
first phase of IFN-I production and curb CMV replication
189 stently, in mice, STING is necessary for the
first phase of IFN-I production that limits early CMV re
190 In the
first phase of in silico sequencing, we explore the vici
191 leted mice (M4K4 iKO) as well as an impaired
first phase of insulin secretion from islets derived fro
192 incretins on beta cells, and focused on the
first phase of insulin secretion to capture the early pa
193 establish that Munc18-1 is required for the
first phase of insulin secretion.
194 The
first phase of major neuronal rearrangements in the brai
195 IkappaBalpha-that define the duration of the
first phase of NF-kappaB activity.
196 We observed a
first phase of parallel evidence integration for multipl
197 ta (SNpc) by regulating the magnitude of the
first phase of postnatal natural cell death which occurs
198 ous manner to control dendrite severing, the
first phase of pruning.
199 elease generated by the mitochondria fuels a
first phase of purinergic signaling that boosts Ca(2+) s
200 This document summarizes the
first phase of quality system guidance developed by the
201 In the
first phase of Shahroud Eye Cohort Study, the 40-64 year
202 st that Msh6 plays a scaffolding role in the
first phase of SHM, in addition to its enzymatic role in
203 e essential function of PIWI proteins in the
first phase of somatic development.
204 The
first phase of study was a method development to effect
205 temporally matched to glottic adduction-the
first phase of swallow motor program.
206 Although the
first phase of T-cell reconstitution after UCB transplan
207 monkey showed delay of gratification in the
first phase of testing.
208 In the
first phase of the 1000 bull genomes project, we sequenc
209 eared from STN to sensorimotor cortex in the
first phase of the adaptation, when a constant rotation
210 The
first phase of the algorithm involved the modeling of th
211 The
first phase of the catalytic cycle involves generation o
212 We report here the results of the
first phase of the Centers for Disease Control and Preve
213 In June 2016, the
first phase of the Chilean Food Labelling and Advertisin
214 For our
first phase of the clinical trial, patients were schedul
215 During the
first phase of the COVID-19 pandemic, there was a marked
216 een 1996 and 2001 in the American arm of the
first phase of the Dialysis Outcomes and Practice Patter
217 tment shrinks further, especially during the
first phase of the evolving injury.
218 s, we observed a significant decrease in the
first phase of the formalin test, but in male mice only.
219 ls in T2D remain trapped in the pro-survival
first phase of the HIF1alpha injury repair response with
220 entry are attractive because they act on the
first phase of the infectious cycle.
221 lication of this method to the data from the
first phase of the International HapMap project resulted
222 This implies that the
first phase of the mammalian radiation--associated with
223 The
first phase of the Marine Resiliency Study (MRS-I) inclu
224 In the
first phase of the reliability study, 123 adult myositis
225 The
first phase of the study (PARTNER1; Sept 15, 2010, to Ma
226 In the
first phase of the study, 3 pathologists held a consensu
227 In the
first phase of the study, 32 farms were surveyed using m
228 In the
first phase of the study, only GDH-positive stool sample
229 In the
first phase of the study, participants with longer stop
230 We present findings from the
first phase of the trial and report on uptake of home-ba
231 in the intention-to-treat population of the
first phase of the trial, for which the primary endpoint
232 er the second vaccine dose to the end of the
first phase of the trial.
233 7, 2016, we enrolled 90 participants for the
first phase of the trial.
234 count </= 350 cells/mul) contributed to the
first phase of the trial.
235 The
first phase of the undertaking consists of an assessment
236 The
first phase of this bioinformatic analysis implements a
237 The
first phase of this effort was the withdrawal of the ser
238 The
first phase of this method elicited 413 open-ended respo
239 This article describes the
first phase of this national initiative, the Family Asse
240 In the
first phase of this pathway, ten Fe/S cluster (ISC) asse
241 During the
first phase of this procedure, one auditory stimulus was
242 The
first phase of this protocol involves identification of
243 In the
first phase of this research, standardized approaches we
244 The
first phase of this study asks: how does the podokinetic
245 In the
first phase of this study, in-depth, semistructured inte
246 The
first phase of this trial was designed to determine the
247 s-stimulus association was formed during the
first phase of training.
248 bstates of the bacterial ribosome during the
first phase of translocation, characterized by intermedi
249 ed with Ag and supplemental tocopherols in a
first phase of treatment followed by a 4-wk clearance ph
250 In the
first phase of UEM, it was possible to obtain snapshot i
251 about the organization and evolution of the
first phases of color processing, the filtering of light
252 trinsic factors that are responsible for the
first phases of embryonic patterning.
253 ipation of specific water molecule(s) in the
first phases of the reaction mechanism of catalase-perox
254 Among 52 studies selected in
first phase,
only renin-angiotensin-aldosterone-system b
255 First-phase (
P = 0.001) and glucose potentiation of argi
256 In the
first phase,
participants were randomly assigned (1:1:1)
257 For the
first phase,
pooled relative risks for renal endpoints w
258 farnesyl moiety exposed state represents the
first phase,
preparing the molecule for polymerization.
259 ergo a two-phase conformational cascade: the
first phase progresses from a metastable prefusion state
260 In the
first phase,
pseudopods extended rapidly, with actin pol
261 The
first-phase reduction of ISP starts as early as 100 micr
262 The
first phase relies on the assembly of a wide contractile
263 In the
first phase,
replicating spirochetes, positioned at vary
264 The
first phase resulted from Ca2+ influx through AMPA recep
265 The
first phase revealed c-Jun as a direct substrate of Cdk5
266 ed two stage assessments; which consisted of
first phase screening of the children for neurodevelopme
267 the human whole blood assay is an efficient
first-phase screening model for inflammation, and a guid
268 ing is a good candidate for amplification of
first-phase secretion by glucose, cyclic adenosine 3':5'
269 ulin secretion with a trend toward increased
first-phase secretion.
270 Although the
first phase seemed to be independent of TNFR1 signaling,
271 In the
first phase,
sentinel cells gather Ags present in tissue
272 tments of 100 and 250 U/ml revealed that the
first-phase sg1b RNA decline began approximately 12 h po
273 l included PMM2-CDG patients, with a 6-month
first-phase single acetazolamide therapy group, followed
274 ine model of late development, we report the
first phase-
specific analysis of biomechanical, structur
275 The
first phase,
spore germination and appressoria formation
276 In the
first phase,
starch and metabolites provided a transient
277 in subjects with low thymic scores, whereas
first-phase T cell increases (perhaps mediated by redist
278 In the
first phase (
the cyclase phase), simple linear hydrocarb
279 During the
first phase,
the actin cytoskeleton promotes mechanotran
280 In a
first phase,
the adherence at 4 months was directly asse
281 To accomplish the objectives of this
first phase,
the Pre-B Project organizers established 4
282 In the
first phases,
the bacteria, decorated with hypoacylated
283 de of the second phase was twice that of the
first phase,
there was stimulation.
284 ystem improved from 86%, 92%, and 67% in the
first phase to 96%, 94%, and 83%, respectively, in the s
285 n) reform plan, launched in 2009, marked the
first phase towards achieving comprehensive universal he
286 e-derived or blood dendritic cells, but only
first phase transfer was observed with Mutz-3 LCs.
287 The
first phase transition involves an initial formation of
288 During the
first phase, '
triggers', such as viral infections or env
289 In the
first phase,
type I genes (hCGbeta3, -5, -7, and -8) acq
290 Median
first-phase viral decay rates were significantly faster
291 d was independent of the correlation between
first-phase viral decline efficiency and RVR.
292 In the
first phase,
viruses carrying various combinations of mu
293 The
first phase was a 65-million-year (My) interval from 425
294 The
first phase was a randomized cross-over dietary interven
295 The
first phase was mainly influenced by vegetation recovery
296 Our results indicate that the
first phase was mediated by dsRNA-induced phosphorylatio
297 In the
first phase,
we compared allele frequencies of 150,080 S
298 For the
first phase,
we develop an algorithm which transforms th
299 In the
first phase,
we retrospectively reviewed the clinical an
300 mixing of the eluted nucleic acids from the
first phase with loading buffer which is facilitated by