ライフサイエンスコーパス: flanking

1 The 5'-flanking 0.4k bp region of Klk1b21 gene responded as an

2 luence on binding, while modification of the flanking 0CG, particularly carboxylation, has a strong p

3 tional transcription, such that the upstream flanking -1 H2A.Z-containing nucleosome is more appropri

4 e for C and G nucleotides in the immediately flanking 5' and 3' regions, respectively.

5 e residues are located in disordered domains flanking a 12-amino acid-long amphipathic helix (residue

6 Sequences having helical segments flanking a central bent aromatic beta-sheet were then sy

7 two nanometric layers enriched in magnesium flanking a core rich in sodium, fluoride and carbonate i

8 synthetic mariner transposon is generated by flanking a DNA sequence with short inverted repeats.

9 M, and L, with nontranslated regions (NTRs) flanking a single open reading frame.

10 m changes in tandemly repeated cis sequences flanking a transposable element (a miniature inverted re

11 otides (5hmCA) and it accumulates in regions flanking active enhancers.

12 chuchner et al and Frohner et al report that flanking amino acids and an underappreciated posttransla

13 e injected plasmids with sequence variations flanking an I-SceI endonuclease recognition site into I-

14 o screen the i-2, i-1, i+1, and i+2 residues flanking Asn at the i position.

15 f DNMT3B acting as a unique sensor of the +1 flanking base.

16 ther than dsDNA, loop or bulge regions, with flanking bases influencing the degree of preference.

17 upport PU.1 binding as a monomer, additional flanking bases were required to invoke sequential dimeri

18 T3' dinucleotide target sites, and different flanking bases within diverse DNA secondary structures.

19 fetime values were almost independent of the flanking bases.

20 omoter, harboring a 250-bp homologous region flanking both sides of the genomic target locus.

21 t by binding to extracellular domains of the flanking CD3 regions of the TCR complex.

22 , NR2F2 directly activated enhancer elements flanking cell cycle genes to drive their expression.

23 comprised of the branchpoint and of the two flanking centers (C4-C5-C6 in aldoheptoses and higher an

24 st when the speed bump was near the end of a flanking chain, and (b) macrocycle cavity size, which wa

25 different substituents (speed bumps) on the flanking chains and two macrocycles with different cavit

26 As topological stabilization of DSB-flanking chromatin is independent of DNA repair, we prop

27 ain protein, ZMYND8, which spreads along the flanking chromatin, but is excluded from the DSB region.

28 arrangement and leads to decompaction of DSB-flanking chromatin, reduction in interchromatin space, a

29 is framed by extensive ZMYND8 domains on the flanking chromatin.

30 s and allows acetylation to spread along the flanking chromatin.

31 How this process works and how it impacts flanking chromosomal regions are poorly understood.

32 cRNA biogenesis, including length of introns flanking circularized exons, repetitive elements such as

33 ed by the nature of the immediately adjacent flanking codons.

34 bronectin adheres the neural tube to the two flanking columns of paraxial mesoderm and is required fo

35 ne amplicon sequencing revealed the dominant flanking community members in both reactors were affilia

36 lso investigated to identify the presence of flanking community members.

37 ll line-based experiments have identified 5'-flanking conserved sequences that control pancreatic and

38 ls containing CpX target sites in randomized flanking context and identified combined effects of CpG

39 ial new links between circRNA biogenesis and flanking CpG island.

40 t palindromic repeat (CRISPR) loci and their flanking CRISPR-associated (cas) genes make up RNA-guide

41 , 28S D2/D3 and a mitochondrial DNA fragment flanking cytochrome oxidase gene subunit II - the interg

42 antly shifted toward the radical cation by a flanking dA.

43 gurations (S (p) and R (p)) at six different flanking dinucleotide sites, i.e. XT and TX (X = A, C, o

44 act weakly with both the ipso-carbons of the flanking Dipp groups and the boron centres of the diazab

45 ntrolled pharmacology study, we measured how flanking distractors influenced detection of a small con

46 3 to 30 bp of sequence that is identical to flanking DNA ("templated" insertions).

47 ose to execute cleavage, open to release the flanking DNA and close again to capture and attack targe

48 ils of the H1 isoforms mainly controlled the flanking DNA orientations.

49 mplexes, the crescent-shaped BMVC recruits a flanking DNA residue to form a BMVC-base plane stacking

50 , the DSB forms hairpin intermediates on the flanking DNA side.

51 tion unit, but rarely more than 50-100 kb of flanking DNA, even when multiple neighboring genes are a

52 and favoring bidirectional progression into flanking DNA, typically to a maximum of 15 nucleotides i

53 ence to shift the histone core toward longer flanking DNA.

54 d polyproline II helices in the proline-rich flanking domain (PRD).

55 hanges in fibril surface characteristics and flanking domain mobility.

56 rone activity against amyloid formation, the flanking domains contribute additional and important cha

57 The polymorphic fibrils differ in their flanking domains rather than the polyglutamine amyloid s

58 We dissect the role of N- and C-terminal flanking domains using protein with the former (htt(NT)

59 ration and the role of the non-polyglutamine flanking domains.

60 eased by targeting both G-quadruplex and its flanking duplex DNA in a naturally occurring dsDNA-ssDNA

61 ds specifically to a 50 bp A+T rich sequence flanking each side of the D IES (Kd ~ 43 nM).

62 ties, and a 100-fold impact of dinucleotides flanking each site.

63 The genomic sequence flanking editing sites is highly conserved, suggesting t

64 MYC thus interacts with its flanking enhancers in a mutually exclusive manner docume

65 itself likely drives its communications with flanking enhancers, rather than vice versa.

66 ption factor (TF) binding regions and at the flanking eRNA initiation regions, both of which are asso

67 organised into smaller chromatin loops than flanking euchromatic mouse chromatin.

68 t AS by binding to exons at coding sequences flanking exons that are more frequently skipped in clock

69 le, we found extended haplotype homozygosity flanking FMF-associated mutations, indicating evolutiona

70 Shielding of NFGAIL-flanking fragments reduces the formation of parallel IAP

71 ular i-motif structure can tolerate specific flanking G-repeats.

72 uplexes, (th)G's hypochromism was larger for flanking G/C residues but its fluorescence quantum yield

73 ailed to detect focal abnormalities or those flanking gaps in IKZF1 probe coverage.

74 nascent transcript levels for several Hsp70 flanking genes also correlate with speckle association a

75 However, flanking genes duplicated in some but not all the affect

76 termined that one enhancer activates the two flanking genes in mammary tissue during pregnancy and la

77 The contribution of the RLIM-flanking genes to the phenotypes of individuals with dif

78 borhoods without significantly affecting the flanking genes.

79 ed on tissue-specific expression patterns of flanking genes.

80 lso observe long-range allosteric changes in flanking helices consistent with winding/unwinding in he

81 ins is concluded to increase the mobility of flanking helices, giving rise to increased off rates for

82 ndicate that when ATP hydrolysis is present, flanking heterologous dsDNA regions increase the reversi

83 cond HLA-B*52:01-associated mutation, K286R, flanking HLA-B*52:01-RI8, was also analyzed.

84 ompleteness of genome fragments and removing flanking host regions from integrated proviruses.

85 nct topologically associating domains (TADs) flanking HoxD, both containing a range of appropriate en

86 quence in its att sites, active 'attB' sites flanking human deleterious mutations were previously ide

87 ilaments are prevented from piling up in the flanking internodes, ensuring a stable neurofilament dis

88 tivated region more rapidly in nodes than in flanking internodes, indicating that neurofilament trans

89 that, in addition to the globular domain, a flanking intrinsically disordered region also recognizes

90 as a result of a recombination event between flanking intronic Alu sequences.

91 ity, and the predominant circRNAs had longer flanking introns and more Alu elements than other circRN

92 usion and instead promoting the retention of flanking introns containing repeated SRSF7 binding sites

93 circulation and RNA editing in back-splicing flanking introns; (ii) a two-stage DE approach of circRN

94 mechanism for setting deletion boundaries by flanking inverted repeats in Tetrahymena thermophila.

95 BIN2 phosphorylation of DSK2 flanking its ATG8 interacting motifs (AIMs) promotes DSK

96 dent lineage-specific segmental duplications flanking LCR16a leading to the emergence of large inters

97 of conserved heptamer and nonamer sequences flanking less well-conserved 12- or 23-bp spacers.

98 slides nucleosomes into positions with more flanking linker DNA than CHD7.

99 However, the flanking/linker DNAs displayed substantial distinct dyna

100 sed under phosphate-replete conditions by 5' flanking lncRNAs prt, prt2, and nc-tgp1, respectively.

101 Recently, adhesive synergy between flanking lysine (Lys, K) and 3,4-Dihydroxyphenylalanine

102 essing cells, and the presence of loxP sites flanking M2 did not alter viral replication or latency i

103 The two flanking markers in both populations delimited the gene

104 The flanking markers related to the QTL reported in this stu

105 lly, and unexpectedly, the crossover rate of flanking markers tens of kilobases away from the sequenc

106 reactions of the morpholine moiety with the flanking meso-aryl groups leads to a sharpened, blue-shi

107 precise deletions based on the alignment of flanking microhomologies (uHs).

108 increase in the proportion of deletions with flanking microhomology, a signature associated with a ba

109 including rs1198588, at a leading risk locus flanking MIR137.

110 cRNAs that interferes with activation of the flanking mRNA promoters.

111 variant H2A.Z from the -1 and +1 nucleosomes flanking NDRs; however, Ino80C's function in transcripti

112 s, of which 68.4% involved associations with flanking non-coding regions of the gene.

113 tations at canonical dinucleotides (73%) and flanking noncanonical positions (27%), and calculate the

114 i contacts between the guanidinium group and flanking nucleobases.

115 e photophysics of (th)G independently of its flanking nucleobases.

116 tures known as R-loops at intergenic spacers flanking nucleolar rRNA genes.

117 Interestingly, either origin-flanking nucleosomes or roadblocks resulted in helicase

118 ere it binds and destabilizes or repositions flanking nucleosomes.

119 etrotransposon presence/absence patterns and flanking nucleotide changes suggest an important influen

120 d resolved these preferences into individual flanking nucleotides and periodic poly(A) tracts that ro

121 whereas the impact of variants at conserved flanking nucleotides is less clear.

122 ened Watson-Crick and reversed non-canonical flanking pairs.

123 nodal adhesion molecule, is regulated by the flanking paranodal junctions.

124 ked to increased purine content of sequences flanking poly(A) sites.

125 n of conserved core PCR primer binding sites flanking polymorphic haplotypes with high information co

126 Targeted sequencing flanking position 1404 in 9 additional macaque mothers a

127 Non-CpG flanking preferences of DNMT3B are highly correlated wit

128 a unique sequence-context specificity, i.e. flanking purines at the 5' end of the mutated nucleotide

129 Our data indicate the PRRAR sequence and the flanking QTQTN sequence are not fixed in vitro; thus, th

130 Interestingly, the inversions are nested or flanking rather than coinciding with the deletion or dup

131 binding site accessibility, as determined by flanking region AU content, could fully explain the disc

132 ophin CH1-CH2 that depends on the N-terminal flanking region but not on bulk affinity.

133 ion of ZmBCH2, we isolated 2036 bp of the 5'-flanking region containing the 263 bp 5'-untranslated re

134 all proteins containing the TM and a limited flanking region homologous to the fusion protein of the

135 matches between the 5-tag of crRNA and the 3-flanking region of target RNA.

136 zed to bp -160 to +42 within the proximal 5' flanking region of the Fbxl2 gene.

137 Deletion analysis of the OsACBP2 5'-flanking region revealed five copies of the seed cis-ele

138 putative regulatory sequence in the ULK1 5'-flanking region, the mutation of which increased ULK1 pr

139 ERF96 participates in DNA interaction in the flanking region.

140 proven by the characterization of transgene flanking regions and the combinations of elements that a

141 ns of SLF genes, resulting in highly similar flanking regions between different types of SLF and betw

142 he high degree of sequence similarity in the flanking regions could often be explained by the presenc

143 in the C-zone (where MyBP-C exists) than in flanking regions devoid of MyBP-C.

144 reening for polymorphism and ensure that the flanking regions do not have length difference that woul

145 Also the flanking regions far away from miRNAs appeared to have h

146 CpG dinucleotides located within binding or flanking regions for the transcriptional regulator CCCTC

147 ment of TFs and cofactors in gene bodies and flanking regions in gene lists without an a priori binar

148 PL35a and RPL23, and ferredoxin, FDX1, whose flanking regions including promoters, terminators and un

149 However, how NAC flanking regions modulate alphaSyn aggregation remains u

150 BKPyV genomes were significantly enriched in flanking regions of 84% of the integration sites.

151 V genomes were significantly enriched in the flanking regions of 84.5% the integration sites, with a

152 Hippocampal cis-meQTL-CpGs are enriched in flanking regions of active promoters, CpG island shores,

153 S-loci of all three S-haplotypes and in the flanking regions of all S-locus genes examined.

154 in intergenic regions, especially at the 5'-flanking regions of protein-coding genes.

155 s revealed potential genetic exchange in the flanking regions of SLF genes, resulting in highly simil

156 ein binding sites and CpG islands within the flanking regions of the circular RNA back-spliced juncti

157 ining all the introns, exons, and 5'- and 3'-flanking regions of the hCYP11B2 gene containing either

158 short precursor miRNA sequences within long flanking regions of the transcript is not known.

159 xamining the evolutionary properties of gene-flanking regions on the X Chromosome, we find evidence t

160 enhancer cluster or parts thereof, Nppb and flanking regions or the entire genomic block spanning Np

161 at topologically associating domain boundary-flanking regions showing high interaction frequencies wi

162 Across species, sequence identity in the SSR-flanking regions was generally low.

163 elongation early in transcription, and in 3' flanking regions where termination is enhanced by TFIIS(

164 l causal variants are enriched in coding and flanking regions, as well as in regulatory elements, and

165 eously to identify genes, predicted promoter flanking regions, transcription factors and CTCF binding

166 nd mature miRNAs are lower than the adjacent flanking regions.

167 s and CO rates were slightly elevated in the flanking regions.

168 C-rich regions and that NRF1 prefers AT-rich flanking regions.

169 ing from both within the G4 motifs and their flanking regions.

170 et cleavage by AGO3 requires both 5'- and 3'-flanking regions.

171 le nucleotide polymorphism (SNP) panels from flanking regions.

172 emergence of global gene regulation via the flanking regulatory landscapes, to optimize a coordinate

173 We identified several potential flanking regulatory sequences, each associated with a su

174 y LIA3 knockout contained common features of flanking regulatory sequences.

175 Two direct cagA-flanking repeats of a genetic element termed CHA-ud were

176 The binding pocket flanking residue Val-339, unlike the equivalent Arg-343

177 ich lines the anesthetic-binding cavity, its flanking residues (132 to 140), and Leu-122, a pore-gati

178 II molecules (HLA-II), which through peptide-flanking residues (PFRs) can extend beyond the limits of

179 We discover that flanking residues and post-translational modifications c

180 lso when seemingly subtle alterations to the flanking residues are introduced.

181 by forming compensatory interactions to the flanking residues including a CpG specific contact to an

182 ytosine tetrameric i-motif can bear ten-base flanking residues.

183 loading intermediate, when either one of the flanking roadblocks was eliminated, the remaining roadbl

184 margin thereby contributing to subsidence of flanking sedimentary basins.

185 rin-like cleavage site itself (NSPRRAR) or a flanking sequence (QTQTN), and we investigated these del

186 olybasic cleavage site itself (NSPRRAR) or a flanking sequence (QTQTN).

187 Splicing Enhancer-like RNA motif enriched in flanking sequence around HIN1-regulated introns.

188 also observed a previously unappreciated CpG flanking sequence bias in major and minor satellite repe

189 ger than transcription factor binding sites, flanking sequence can be used to target specific sites.

190 fied combined effects of CpG recognition and flanking sequence interaction together with complex cont

191 -copy plasmids with restricted amounts of 5' flanking sequence plus tDNA.

192 well as DNMT3A Arg882His variant acquire CpG flanking sequence preference akin to that of DNMT3B, whi

193 the enzymatic activity, CpG specificity and flanking sequence preference of DNMT3A.

194 tle differences suggesting a co-evolution of flanking sequence preferences and cellular DNMT targets.

195 Importantly, we show that the flanking sequence preferences of DNMT1 highly correlate

196 Comparison of the flanking sequence preferences of human and mouse DNMT3B

197 ubsets of IESs and that their mechanisms for flanking sequence recognition are distinct.

198 followed by sequencing, we recovered 388 888 flanking sequence tags (FSTs) from 21 741 insertion line

199 A total of 126 flanking sequence tags (FSTs) were recovered from the an

200 uncover the intricate interplay between CpG-flanking sequence, DNMT1-mediated base flipping and the

201 DNA substrates revealing that DNMT1 employs flanking sequence-dependent base flipping mechanisms, wi

202 repressive histone mark H3K9me3, and AT-rich flanking sequence.

203 guanines and a correctly orientated A/T-rich flanking sequence.

204 ceptor sites including those with suboptimal flanking sequences and sites located within cysteine-ric

205 on and highly dispersed in the genome, their flanking sequences are conserved at about 90 to 95% iden

206 In a few rare cases, flanking sequences are identical across species of Jugla

207 These flanking sequences are inverted repeats with the copies

208 nt defects, but minor perturbations from the flanking sequences are sufficient to reduce the defects

209 DNA methylation rates were more affected by flanking sequences at non-CpG than at CpG sites.

210 o different LOV2-based switches reveals that flanking sequences can lead to relaxation times up to 11

211 ification of transgene integration sites and flanking sequences in three CHO cell lines.

212 Moreover, flanking sequences influence the conformational dynamics

213 We determined that the flanking sequences near G-boxes help determine in vitro

214 erfering RNAs were enriched in the 5' and 3' flanking sequences of nonadditively expressed genes in t

215 a values predicted from structures, although flanking sequences of S-palmitoylated sites are enriched

216 In this study, we demonstrate that the 5'-flanking sequences of the C(4) type phosphoenolpyruvate

217 tion of subtle details such as the effect of flanking sequences or binding cooperativity.

218 Analysis of flanking sequences showed that almost all the ARGs could

219 develops a general approach for identifying flanking sequences that can be used to drive transgene e

220 g in increased Nppa expression when Nppb and flanking sequences were deleted.

221 The RPL23 flanking sequences were further tested using the zeocin

222 structs expressing the HeV F TM with limited flanking sequences were synthesized.

223 ighly expressed genes in Chlamydomonas whose flanking sequences were tested for the ability to drive

224 CpG target sites in the context of variable flanking sequences.

225 y favoring deformation of the repeat and the flanking sequences.

226 nition of distinct target RNA 3' protospacer flanking sequences.

227 op) recognizes the CpG dinucleotides in a +1 flanking site-dependent manner.

228 ing a CpG specific contact to an A at the +1 flanking site.

229 in balancing the interaction with different flanking sites.

230 The two flanking SNPs for Sbwm1 can effectively separate the res

231 ons of the capsid (CA) domain of Gag and the flanking spacer peptide SP1 that stabilize VLPs, but muc

232 ds on the position and nature of nucleotides flanking splice sites, and on structural interactions be

233 thogens and whose activity is repressed by a flanking substrate-binding leucine-rich repeat (LRR) dom

234 central edgewise loop, propeller loop and 5' flanking terminal.

235 mers, with a pair of C-terminal domains from flanking tetramers completing the synaptic interface.

236 the high charge-density saccharide residues flanking the "canonical" antithrombin-binding hexasaccha

237 nditional Pam(cKO/cKO) mice, with loxP sites flanking the 2 exons deleted in the global Pam(KO/KO) mo

238 Genomic sequences flanking the 3'-side of L1s were amplified from neuronal

239 The model shows how the sequences flanking the amyloid core modulate aggregation behavior.

240 el conformation, suggesting that the residue flanking the amyloidogenic peptide contributes to the st

241 histone 3 lysine 27 and histone 3 lysine 18) flanking the ATF3 promoter region.

242 "sensory motif" and two loops, RL1 and RL2, flanking the ATP-binding site playing a significant role

243 es circRNA biogenesis by binding the introns flanking the back-splicing junctions and that this contr

244 ors such as 53BP1 and BRCA1 on the chromatin flanking the break site.

245 selective elimination of glycosylation sites flanking the CD4bs, and 2) minimize the nND immune respo

246 ypsy retrotransposons in the heterochromatin flanking the centromeres.

247 disordered, low-complexity N-terminal region flanking the coil-coiled self-association domain.

248 The specificity of AR extends to the regions flanking the core 15-bp site, where isothermal calorimet

249 elative position of the core motif and bases flanking the core motif play an important role in modula

250 ing affinity is greatly enhanced by residues flanking the crystallographically-defined recognition mo

251 adopt multiple conformations in the regions flanking the cysteine noose.

252 nt from the 3' end and 9 nt from the 5' end flanking the damage.

253 Analysis of the genomic region flanking the deletion unveiled a large intragenic deleti

254 es while sparing well-positioned nucleosomes flanking the enhancer core, indicating that inducible TF

255 nd UV-VIS absorbance spectroscopy of samples flanking the fat, may be an important factor in cellular

256 y regulated by the N- and C-terminal regions flanking the FH1-FH2 domains.

257 gest that removal of the repressed chromatin flanking the GAA tract might contribute to rescue FXN to

258 Moreover, we show that sequences flanking the highly conserved Aux/IAA W-P motif do not i

259 novel six-amino-acid C-terminal motif (CTM) flanking the homeodomain that serves as a major determin

260 ver, the analysis of the enhancer landscapes flanking the HoxD cluster reveals that the bimodal regul

261 An analysis of the amino-acid residues flanking the hydrolyzed bonds revealed a set of residue

262 am open reading frames, specific nucleotides flanking the initiating AUG codon, protein coding sequen

263 We have identified two CTCF binding sites flanking the locus and two associated with a super-enhan

264 When the regions flanking the miRNA coding sequence are highly methylated

265 We used a TAD flanking the mouse HoxD cluster to study how these regul

266 igned a series of single guide RNAs (sgRNAs) flanking the mutation and provided different single-stra

267 ther enables recognition of charged residues flanking the nascent TMD and thus explains the specifici

268 the Neurexin2 AS4 exon, compared with those flanking the Neurexin1 and Neurexin3 AS4 exons under joi

269 flexibility to wedge the RCC1 beta-propeller flanking the NLS against its lateral surface, preventing

270 sliding has been shown to depend on the DNA flanking the nucleosome, transcription factor binding at

271 d, to a lesser extent, in the switch regions flanking the nucleotide binding site, can shed light on

272 cleavage, we mutagenized the eight residues flanking the prelamin A scissile bond (TRSY LLGN) to all

273 DNA sequences immediately flanking the previously defined AICE motif controlled th

274 Quantification of reads flanking the programmed ribosomal frameshifting (PRF) si

275 , and show increased de novo point mutations flanking the rearrangement junctions.

276 ity is strongly amplified by the DNA regions flanking the recognition site, which contain long tracts

277 Additionally, the exonic segments flanking the retained introns appeared to be more enrich

278 eading to excitation of a tryptophan residue flanking the retinal chromophore, as a first manifestati

279 IV, and VI, while using a bipartite sequence flanking the RING domain to degrade PML I.

280 Here, we detect intrinsic instability in DNA flanking the RNA-3' side of R-loops, which Cas12a can ex

281 Interestingly, DNA flanking the RNA-5' side of R-loops is not intrinsically

282 interactions occur with unstructured regions flanking the rod domain during oligomeric assembly.

283 , we discovered ligase-activity determinants flanking the S1 site, namely LAD1 and LAD2 located aroun

284 te, and bacterial EndoV binds only 2 or 3 nt flanking the scissile phosphate.

285 Sema3D expression flanking the sensory tissue in vestibular organs suggest

286 d main interaction sites for acidic residues flanking the SIM.

287 We also noted that residues flanking the SP motif, such as the bulky Tyr(1) next to

288 a pronounced influence of the DNA sequences flanking the target CpG site on DNMT1 activity.

289 y recombination requiring only 50-bp regions flanking the target gene.

290 ade the upstream and downstream RNA segments flanking the target sequence upon hybridization to speci

291 of a short protospacer adjacent motif (PAM) flanking the target site, and subsequent R-loop formatio

292 a deep mutational scan showing that residues flanking the Tn-glycan contributed significant binding e

293 e promoter elements, which are DNA sequences flanking the transcription start site (TSS) that help di

294 The Phi31 and Bxb1 integrase attP sites flanking the transgene will also enable rapid directiona

295 us flgM allele were restricted to two codons flanking the translation-defective codon.

296 nformational changes control the path of DNA flanking the transposon end and the generation of DNA-bi

297 nces, we have derived 20-amino-acid peptides flanking this region of interest in order to test the ab

298 ation-the addition of subsidiary cells (SCs) flanking two dumbbell-shaped guard cells (GCs)-is linked

299 a HSP78 (LmxHSP78+/-) were generated using a flanking UTR-based multifragment ligation strategy and t

300 ies of recombination signal sequences (RSSs) flanking Vbeta gene segments suppress the assembly and e