ライフサイエンスコーパス: flavin-adenine dinucleotide

1 nicotinamide adenine dinucleotide), and FAD (flavin adenine dinucleotide).

2 e and has stoichiometric amounts of heme and flavin adenine dinucleotide.

3 active oxygen species (ROS) formation at the flavin adenine dinucleotide.

4 adenylate cofactors NAD(P), coenzyme A, and flavin adenine dinucleotide.

5 with potential binding sites for NAD(P)H and flavin adenine dinucleotide.

6 d a molecular weight of 22,000 and contained flavin adenine dinucleotide.

7 ion of nicotinamide adenine dinucleotide and flavin adenine dinucleotide.

8 e dehydrogenase with a bicovalently attached flavin adenine dinucleotide.

9 e flavin coenzymes flavin mononucleotide and flavin adenine dinucleotide.

10 spectra of ALR bound to oxidized and reduced flavin adenine dinucleotide.

11 rescent metabolic coenzymes reduced NADH and flavin adenine dinucleotide.

12 to coenzyme forms flavin mononucleotide and flavin adenine dinucleotide.

13 th stoichiometric amounts of the chromophore flavin-adenine dinucleotide.

14 The protein contained flavin adenine dinucleotide and exhibited NADPH quinone

15 ineages, whereas redox and light sensing via flavin adenine dinucleotide and flavin mononucleotide co

16 Both enzymes use flavin adenine dinucleotide and folate in their reaction

17 ers also formed in mutants that did not bind flavin adenine dinucleotide and in truncated peptides wi

18 ructure harbors typical FMO aspects with the flavin adenine dinucleotide and NAD(P)H binding domains

19 nent, was found to contain approximately one flavin adenine dinucleotide and one ferredoxin-type [2Fe

20 ites across the two molecules, involving the flavin adenine dinucleotide and substrate-binding pocket

21 revealed that the two well-known cofactors, flavin adenine dinucleotide and the photoantenna 6,7-dim

22 li, was shown to possess noncovalently bound flavin adenine dinucleotide and to exhibit L-2-hydroxygl

23 n glucose oxidase, electron transfer between flavin-adenine-dinucleotide and tryptophan(s)/tyrosine(s

24 llular NADPH, across a chain comprising FAD (flavin adenine dinucleotide) and two haems, to reduce ex

25 The NADH, flavin adenine dinucleotide, and Fe-S center binding sit

26 factor in addition to a molybdenum cofactor, flavin adenine dinucleotide, and FeS centers, were purif

27 educed nicotinamide adenine dinucleotide and flavin adenine dinucleotide, and the absorption of cytoc

28 BLUF domains (sensors of blue light using flavin adenine dinucleotide) are a group of flavin-conta

29 ores (riboflavin, flavin mononucleotide, and flavin adenine dinucleotide) are notoriously similar eve

30 ated WC-1 and WC-2 confirmed that WC-1, with flavin adenine dinucleotide as a cofactor, is the blue l

31 the oxidation of d-lactate to pyruvate using flavin adenine dinucleotide as a cofactor; knowledge of

32 lation, it depends on magnesium and utilizes flavin adenine dinucleotide as substrate to attach the f

33 However, NAD(P)H and flavin adenine dinucleotide binding motifs are conserved

34 teine-to-serine substitution remote from the flavin adenine dinucleotide binding site decouples confo

35 ce of DWF1 shows significant similarity to a flavin adenine dinucleotide-binding domain conserved in

36 this family is that the sequence of the key flavin adenine dinucleotide-binding domain is split into

37 7 of 10 dwf1 mutations directly affected the flavin adenine dinucleotide-binding domain.

38 se-methanol-choline oxidoreductase family of flavin adenine dinucleotide-binding enzymes catalyzing h

39 The input sensor in Aer is a flavin adenine dinucleotide-binding PAS domain, which is

40 mical studies reveal that M6766 binds to the flavin adenine dinucleotide-binding pocket in ERO1alpha

41 This gene is predicted to encode a conserved flavin adenine dinucleotide-binding protein involved in

42 hey had open reading frames that predicted a flavin adenine dinucleotide-binding site, multiple N-gly

43 ial N-glycosylation sites, and a presumptive flavin adenine dinucleotide-binding site.

44 utative redox active site CAVC as well as an flavin-adenine dinucleotide-binding domain are highly co

45 that the amino terminus domain of IrtA is a flavin-adenine dinucleotide-binding domain essential for

46 Blue light using flavin adenine dinucleotide (BLUF) proteins are essentia

47 t MHPCO is a homotetrameric protein with one flavin adenine dinucleotide bound per subunit.

48 s a flavoprotein containing covalently bound flavin adenine dinucleotide, but no detectable heavy met

49 th the flavoprotein SdhA, directly bound the flavin adenine dinucleotide co-factor, and was required

50 hotoinduced electron transfer from a reduced flavin adenine dinucleotide cofactor (FADH(-)) to the bo

51 rified NDH-2 contains a non-covalently bound flavin adenine dinucleotide cofactor and oxidizes NADH w

52 clic electron transfer between the catalytic flavin adenine dinucleotide cofactor and the damaged DNA

53 ht activation, electron transfer between the flavin adenine dinucleotide cofactor and tryptophan resi

54 tate of the electron transport system via an flavin adenine dinucleotide cofactor bound to a PAS doma

55 The flavin adenine dinucleotide cofactor has an unusual bent

56 the entire pH range under investigation, the flavin adenine dinucleotide cofactor of GOx changed dire

57 unohistochemistry, disrupts the light-driven flavin adenine dinucleotide cofactor photoreduction, pro

58 d for Sdh1 flavination (incorporation of the flavin adenine dinucleotide cofactor).

59 hat the compound interacts directly with the flavin adenine dinucleotide cofactor, blocking the menaq

60 tors but unique in having a PAS domain and a flavin-adenine dinucleotide cofactor that is postulated

61 cotinamide adenine dinucleotide and oxidized flavin adenine dinucleotide cofactors we use optical ima

62 ws in vitro responsiveness to high cofactor (flavin adenine dinucleotide) concentrations.

63 The acyl-CoA dehydrogenases are a family of flavin adenine dinucleotide-containing enzymes that cata

64 ACAD9 is a flavin adenine dinucleotide-containing flavoprotein, and

65 In Neurospora, the flavin adenine dinucleotide-containing protein WHITE COL

66 generates an inactive enzyme unable to bind flavin adenine dinucleotide covalently.

67 ned to flavin absorption and conjugated with flavin adenine dinucleotide, creating a nanoagonist capa

68 Flavin adenine dinucleotide dependent glucose dehydrogen

69 Here we report the identification of a novel flavin adenine dinucleotide-dependent amine oxidase (ren

70 Here we report a flavin adenine dinucleotide-dependent enzyme, Morus alba

71 ression of whiE ORFVIII, encoding a putative flavin adenine dinucleotide-dependent hydroxylase that c

72 e cytochrome P450 monooxygenase (TamI) and a flavin adenine dinucleotide-dependent oxidase (TamL), wh

73 midine/spermine N1-acetyltransferase and the flavin adenine dinucleotide-dependent polyamine oxidase

74 talyses removal of H3K4me2/H3K4me1 through a flavin-adenine-dinucleotide-dependent oxidation reaction

75 , such as LOV and BLUF (blue-light-utilizing flavin adenine dinucleotide) domains, cryptochromes, and

76 a DSOR-like charge transfer interaction with flavin adenine dinucleotide, eliminating the need for cy

77 n addition, NADH ED-FRAP was correlated with flavin adenine dinucleotide (FAD(+)) fluorescence.

78 .1 atom/mol), Fe (21 +/- 1.6 atoms/mol), and flavin adenine dinucleotide (FAD) (0.83 +/- 0.1 mol/mol)

79 ltage sensing (LOV) and Blue-Light-Utilizing flavin adenine dinucleotide (FAD) (BLUF) domains represe

80 is required for formation of C4a-hydroperoxy flavin adenine dinucleotide (FAD) (FAD(C4aOOH)), a key f

81 ced nicotine adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD) - is demonstrated.

82 ively reported based on enzyme sensors using flavin adenine dinucleotide (FAD) -dependent d-amino aci

83 tion of the histone tail lysine (H3K4), with flavin adenine dinucleotide (FAD) acting as cofactor.

84 nzyme activity by forming a compact N-formyl flavin adenine dinucleotide (FAD) adduct that spares the

85 at contain noncovalently or covalently bound flavin adenine dinucleotide (FAD) analogues were studied

86 ophilum at 1.6 A resolution, in complex with flavin adenine dinucleotide (FAD) and a bacterial lipid.

87 activated electron-transfer reaction between flavin adenine dinucleotide (FAD) and a chain of tryptop

88 se is a homodimeric flavoenzyme containing a flavin adenine dinucleotide (FAD) and a redox-active dis

89 etrahydrofolate (CH(2)THF), while MnmG binds flavin adenine dinucleotide (FAD) and a reduced nicotina

90 ve a common structural fold, a dependence on flavin adenine dinucleotide (FAD) and an internal photoa

91 nt HlmI was purified from E. coli with bound flavin adenine dinucleotide (FAD) and converts reduced h

92 also contain other metabolite caps including flavin adenine dinucleotide (FAD) and dephosphoCoA (dpCo

93 The riboflavin (RF) cofactors, flavin adenine dinucleotide (FAD) and flavin mononucleot

94 s soluble and contains an equimolar ratio of flavin adenine dinucleotide (FAD) and flavin mononucleot

95 Riboflavin, in its cofactor forms flavin adenine dinucleotide (FAD) and flavin mononucleot

96 vin as the direct precursor of the cofactors flavin adenine dinucleotide (FAD) and flavin mononucleot

97 The adsorption of flavin adenine dinucleotide (FAD) and glucose oxidase (G

98 ia a light-driven hydrogen-bond switch among flavin adenine dinucleotide (FAD) and glutamine and tyro

99 PvdA requires both flavin adenine dinucleotide (FAD) and nicotinamide adeni

100 de ring opening reactions in the presence of flavin adenine dinucleotide (FAD) and nicotinamide adeni

101 the formation of the essential flavocoenzyme flavin adenine dinucleotide (FAD) and plays an important

102 interactions on the stabilization of reduced flavin adenine dinucleotide (FAD) and substrate/product

103 ns in the dihedral and librational angles of flavin adenine dinucleotide (FAD) and tryptophan (Trp) r

104 flux between flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) and/or the electron ac

105 The riboflavin derivatives FMN and flavin adenine dinucleotide (FAD) are critical cofactors

106 Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are essential riboflav

107 yglutamate (MTHF) and the catalytic cofactor flavin adenine dinucleotide (FAD) are noncovalently boun

108 Tryptophan and flavin adenine dinucleotide (FAD) are separated by a 10

109 The endogenous fluorophores NADH and flavin adenine dinucleotide (FAD) are two of the princip

110 hyltetrahydrofolate (CH(3)-H(4)folate) using flavin adenine dinucleotide (FAD) as a cofactor.

111 al to the molecular clock using a pterin and flavin adenine dinucleotide (FAD) as chromophore/cofacto

112 hyltetrahydrofolate (CH(3)-H(4)folate) using flavin adenine dinucleotide (FAD) as cofactor.

113 nstead methylenetetrahydrofolate and reduced flavin adenine dinucleotide (FAD) as essential cofactors

114 heir interactions and the functional role of flavin adenine dinucleotide (FAD) binding in CRYs remain

115 t DntB contains the highly conserved ADP and flavin adenine dinucleotide (FAD) binding motifs charact

116 rs of electrons requiring photoactivation of flavin adenine dinucleotide (FAD) bound near a triad of

117 oS contains a flavin cofactor, identified as flavin adenine dinucleotide (FAD) by fluorescence spectr

118 purified PrnF protein catalyzes reduction of flavin adenine dinucleotide (FAD) by NADH with a k(cat)

119 s sheds light on the early events around the Flavin Adenine Dinucleotide (FAD) chromophore in the lig

120 AidB was recently shown to possess a flavin adenine dinucleotide (FAD) cofactor and to bind t

121 produce type II symptoms occur close to the flavin adenine dinucleotide (FAD) cofactor binding site.

122 , cycles of reduction and reoxidation of the flavin adenine dinucleotide (FAD) cofactor depend on rat

123 ichia coli photolyase, photoreduction of the flavin adenine dinucleotide (FAD) cofactor in its neutra

124 en a spin label and an enzymatically reduced flavin adenine dinucleotide (FAD) cofactor in P. denitri

125 DHA(R451) so that covalent attachment of the flavin adenine dinucleotide (FAD) cofactor is supported.

126 As observed in homologous ETFs, the flavin adenine dinucleotide (FAD) cofactor of ETF forms

127 Adenosine is a structural part of the flavin adenine dinucleotide (FAD) cofactor of the dehydr

128 , which lacks the covalent attachment to the flavin adenine dinucleotide (FAD) cofactor present in th

129 r, has a HAMP domain and a PAS domain with a flavin adenine dinucleotide (FAD) cofactor that senses t

130 homology region (PHR) carrying the oxidized flavin adenine dinucleotide (FAD) cofactor, and a crypto

131 ion of two key glutamic acids as well as the flavin adenine dinucleotide (FAD) cofactor.

132 the spectral properties of its tightly bound flavin adenine dinucleotide (FAD) cofactor.

133 proteins activated by photoexcitation of the flavin adenine dinucleotide (FAD) cofactor.

134 llular respiration through a redox-sensitive flavin adenine dinucleotide (FAD) cofactor.

135 formation of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) cofactors, is internal

136 are important redox enzymes that contain two flavin adenine dinucleotide (FAD) cofactors, with contra

137 The enzyme contains 1 mol of flavin adenine dinucleotide (FAD) covalently linked to C

138 hF) of p-cresol methylhydroxylase (PCMH) has flavin adenine dinucleotide (FAD) covalently tethered to

139 The gravimetric results obtained on flavin adenine dinucleotide (FAD) depended on pH.

140 tone demethylase LSDl (KDMlA) belongs to the flavin adenine dinucleotide (FAD) dependent family of mo

141 adaic enzyme EIS sensor, which used DET-type flavin adenine dinucleotide (FAD) dependent glucose dehy

142 the cytoplasm, where the PAS (Per-ARNT-Sim)-flavin adenine dinucleotide (FAD) domain senses redox ch

143 on of the NAD(P)H domain with respect to the flavin adenine dinucleotide (FAD) domain that precludes

144 responses were matched by inverted biphasic flavin adenine dinucleotide (FAD) fluorescence transient

145 5'-nucleotidase, resulted in accumulation of flavin adenine dinucleotide (FAD) in culture supernatant

146 d ultrafast photoreduction of oxidized state flavin adenine dinucleotide (FAD) in subpicosecond and o

147 es a reaction in two parts: reduction of the flavin adenine dinucleotide (FAD) in the enzyme by reduc

148 reduction of FMN by electrons from NADPH and flavin adenine dinucleotide (FAD) in the reductase domai

149 Flavin adenine dinucleotide (FAD) interacts with flavopr

150 Flavin adenine dinucleotide (FAD) is involved in importa

151 Flavin adenine dinucleotide (FAD) is one of the primary

152 The cofactor flavin adenine dinucleotide (FAD) is required for the ca

153 we demonstrate that the cellular metabolite flavin adenine dinucleotide (FAD) is used as a non-canon

154 tive folding was shown to depend on cellular flavin adenine dinucleotide (FAD) levels but not on ubiq

155 nd that removal of the electron-transferring flavin adenine dinucleotide (FAD) moiety from both prote

156 The flavin adenine dinucleotide (FAD) moiety of Frd is unusu

157 t in addition to having a tightly associated flavin adenine dinucleotide (FAD) moiety, yeast Ero1p is

158 PA) capture probes prebound to electroactive flavin adenine dinucleotide (FAD) molecules, and a signa

159 TftC was an NADH:flavin adenine dinucleotide (FAD) oxidoreductase.

160 studies of Aer suggested that it might use a flavin adenine dinucleotide (FAD) prosthetic group to mo

161 eductase (MMOR), which contains [2Fe-2S] and flavin adenine dinucleotide (FAD) prosthetic groups.

162 he active site, where a non-covalently bound flavin adenine dinucleotide (FAD) sits at the base of an

163 which covalently attach to the LSD1 cofactor flavin adenine dinucleotide (FAD) to inhibit demethylase

164 5 is required for the covalent attachment of flavin adenine dinucleotide (FAD) to protein Sdh1, a sub

165 ic dehydrogenase domain (DH(CDH)) containing flavin adenine dinucleotide (FAD), a cytochrome domain (

166 ia, with a decrease in the cellular level of flavin adenine dinucleotide (FAD), a metabolic cofactor

167 , shown to possess stoichiometric amounts of flavin adenine dinucleotide (FAD), and confirmed to have

168 asured the 2P-excitation spectra of NAD(P)H, flavin adenine dinucleotide (FAD), and lipoamide dehydro

169 P450-type heme, flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), and tetrahydrobiopter

170 but not by the addition of L-arginine, heme, flavin adenine dinucleotide (FAD), flavin mononucleotide

171 ps the excited state of the active cofactor, flavin adenine dinucleotide (FAD), in a highly bent geom

172 contains an N-terminal PAS domain that binds flavin adenine dinucleotide (FAD), senses aerotactic sti

173 enine dinucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD), to assess the metabol

174 They usually bind two chromophores: flavin adenine dinucleotide (FAD), which forms the activ

175 ith isotopically labeled riboflavin (Rf) and flavin adenine dinucleotide (FAD), which permit the firs

176 aks were due to the redox of enzyme cofactor flavin adenine dinucleotide (FAD), which was not the par

177 e atomic crystal structures of the catalytic flavin adenine dinucleotide (FAD)- and heme-binding doma

178 previously characterized BdlA homolog is the flavin adenine dinucleotide (FAD)-binding Aer, the redox

179 rochemical analysis of this and the isolated flavin adenine dinucleotide (FAD)-binding domain in the

180 oach yielded a polypeptide that included the flavin adenine dinucleotide (FAD)-binding domain of nNOS

181 esolution of the three domains of d-LDH: the flavin adenine dinucleotide (FAD)-binding domain, the ca

182 These proteins comprise two modules: a flavin adenine dinucleotide (FAD)-binding module and a t

183 ORF3 encodes a putative flavin adenine dinucleotide (FAD)-binding oxidoreductase

184 cytes deficient in flavin mononucleotide and flavin adenine dinucleotide (FAD)-collectively known as

185 Because LSD1 belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidas

186 Flavin adenine dinucleotide (FAD)-dependent bacterial ol

187 ient composite for electron transfer between flavin adenine dinucleotide (FAD)-dependent glucose dehy

188 A new extracellular flavin adenine dinucleotide (FAD)-dependent glucose dehy

189 SgcC3 unveiled the following: (i) SgcC3 is a flavin adenine dinucleotide (FAD)-dependent halogenase;

190 KMO is a flavin adenine dinucleotide (FAD)-dependent monooxygenas

191 w revealed that (i) SgcC is a two-component, flavin adenine dinucleotide (FAD)-dependent monooxygenas

192 line dehydrogenase domain that catalyzes the flavin adenine dinucleotide (FAD)-dependent oxidation of

193 ve evolved from an ancestor functioning as a flavin adenine dinucleotide (FAD)-dependent oxidocyclase

194 Here, we show that the mitochondrial flavin adenine dinucleotide (FAD)-linked sulfhydryl oxid

195 recognizes the flavin moiety of both FMN and flavin adenine dinucleotide (FAD).

196 enine dinucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD).

197 methylglycine) and contains covalently bound flavin adenine dinucleotide (FAD).

198 h contains a molecule of noncovalently bound flavin adenine dinucleotide (FAD).

199 n from the enzyme's fluorescent active site, flavin adenine dinucleotide (FAD).

200 ined high levels of noncovalently associated flavin adenine dinucleotide (FAD).

201 terodimers containing a single equivalent of flavin adenine dinucleotide (FAD).

202 tive enzyme-substrate complexes with reduced flavin adenine dinucleotide (FAD).

203 mutant that has greatly reduced affinity for flavin adenine dinucleotide (FAD).

204 In PdR, the flavin adenine dinucleotide (FAD/FADH2) redox center act

205 Flavin-adenine dinucleotide (FAD) dependent glucose dehy

206 rm this role: 5'-phosphoriboflavin (FMN) and flavin-adenine dinucleotide (FAD).

207 ced flavins (flavin mononucleotide [FMN] and flavin adenine dinucleotide [FAD]) and cob(III)alamin to

208 between VVD residue Cys108 and its cofactor flavin adenine dinucleotide(FAD), and prompts VVD switch

209 four, bis-His-ligated, c-type hemes and one flavin adenine dinucleotide, FAD.

210 steady-state kinetic mechanism of the active flavin adenine dinucleotide-(FAD-) containing form of th

211 or of a photolyase is a two-electron-reduced flavin adenine dinucleotide (FADH(-)).

212 e (4HPA) 3-monooxygenase (HpaB) is a reduced flavin adenine dinucleotide (FADH(2)) utilizing monooxyg

213 TcpA is a reduced flavin adenine dinucleotide (FADH2)-dependent monooxygen

214 ation of the enzyme indicated that a reduced flavin adenine dinucleotide (FADH2)-utilizing monooxygen

215 apparent molecular mass of 47 kDa, requires flavin adenine dinucleotide for activity, has NADH-speci

216 The dynamics of electron transfer to excited flavin adenine dinucleotide from a neighboring tyrosine

217 ERO1alpha followed by displacement of bound flavin adenine dinucleotide from the active site of the

218 explains why premixing of FDHs with reduced flavin adenine dinucleotide generally results in abolish

219 me composed of an Aspergillus flavus-derived flavin adenine dinucleotide glucose dehydrogenase (AfGDH

220 Fungi-derived flavin adenine dinucleotide glucose dehydrogenases (FADG

221 icotinamide adenine dinucleotide phosphate , flavin adenine dinucleotide , glutathione disulfide/glut

222 tes bind in close proximity to the catalytic flavin adenine dinucleotide group, substantial flexibili

223 he distance and orientation between MTHF and flavin adenine dinucleotide in At-Cry3 is similar to tha

224 s between the flavin and adenine moieties of flavin adenine dinucleotide in four redox forms of the o

225 TcuB transfers electrons from reduced flavin adenine dinucleotide in the Tcb dehydrogenase (Tc

226 nicotinamide adenine dinucleotide) and FAD (flavin adenine dinucleotide) in vitro.

227 to FMN (K(D) approximately 4 microM) than to flavin adenine dinucleotide (K(D) approximately 12 micro

228 Ac92 has homology to the family of flavin adenine dinucleotide-linked sulfhydryl oxidases a

229 a molecular mass of 45 kDa and contains one flavin adenine dinucleotide molecule per mole but lacks

230 icotinamide adenine dinucleotide (phosphate)/flavin adenine dinucleotide (NAD[P]H/FAD) autofluorescen

231 a protein complex composed of oxidoreductase flavin adenine dinucleotide/NAD(P)-binding subunit (Dred

232 degradation, likely due to the imbalance of flavin adenine dinucleotide/nicotinamide adenine dinucle

233 .4 mol of acid-labile sulfur, and 0.7 mol of flavin adenine dinucleotide per mol of protein.

234 n a reduction of the binding affinity of the flavin-adenine dinucleotide prosthetic group.

235 recognition coincided with the loss of FAD (flavin-adenine dinucleotide) recognition in all isolates

236 ne, which encodes a 399-amino-acid NAD+- and flavin adenine dinucleotide-requiring enzyme responsible

237 le recognition and segmentation based on the flavin adenine dinucleotide signal revealed that quantif

238 anaerobic levels, and binding of NADH to the flavin-adenine dinucleotide site seemed to prevent oxyge

239 However, with flavin-adenine dinucleotide site-binding substrate NADH

240 Among VB2 metabolic enzymes, flavin adenine dinucleotide synthase (FADS) is the only

241 After reconstitution with flavin adenine dinucleotide, the resulting protein was i

242 ), also known as acetolactate synthase, is a flavin adenine dinucleotide-, thiamine diphosphate- and

243 ur subunits that contain a covalently linked flavin adenine dinucleotide, three different iron-sulfur

244 at m5U54 is added by the enzyme TrmFO using flavin adenine dinucleotide together with N5,N10-methyle

245 ed in the literature for flavodoxin and free flavin adenine dinucleotide were simulated based on sele

246 precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide, which are essential coenzym

247 ates in the Krebs cycle to generate NADH and flavin adenine dinucleotide, which are further oxidized