ライフサイエンスコーパス: fluidity

1 fferences in the local chain dynamics (i.e., fluidity).

2 rs on the resulting cell elastic modulus and fluidity.

3 ollective accuracy of a cluster by improving fluidity.

4 entially by increasing the cellular membrane fluidity.

5 lation and redundancy while allowing spindle fluidity.

6 formation of neuronal synapses and membrane fluidity.

7 the lipid composition as well as to membrane fluidity.

8 on important molecular processes that affect fluidity.

9 ) drug, significantly increases mycomembrane fluidity.

10 olipids, which ultimately reduce ER membrane fluidity.

11 nce of mature HDL particles with low surface fluidity.

12 n distinct changes in emulsion stability and fluidity.

13 nt local structural fluctuations and crystal fluidity.

14 th can be used by cells to maintain membrane fluidity.

15 ting cellular lipid composition and membrane fluidity.

16 and phospholipids to control proper membrane fluidity.

17 thin supported biomembranes with native-like fluidity.

18 id lipid domains, affecting overall membrane fluidity.

19 g of cadherin to actin and cell-cell contact fluidity.

20 atty acid composition and increased membrane fluidity.

21 ng levels of lipid desaturation and membrane fluidity.

22 ion with phospholipids is driven by membrane fluidity.

23 butes to increased whole-cell compliance and fluidity.

24 s, in addition to the modulation of membrane fluidity.

25 ted actin structures and the plasma membrane fluidity.

26 ty acids required to optimize membrane lipid fluidity.

27 ids play key roles in membrane curvature and fluidity.

28 zyl alcohol-mediated enhancement of membrane fluidity.

29 s mediated by the physical property of lipid fluidity.

30 membrane or changes in membrane potential or fluidity.

31 rated fatty acyl chains, determines membrane fluidity.

32 -potential, phase transition temperature and fluidity.

33 The net effect is to reduce membrane fluidity.

34 to a sigma(W)-dependent decrease in membrane fluidity.

35 ing and reporter lipids, and control bilayer fluidity.

36 membrane properties such as permeability and fluidity.

37 emphasizing the role of glycine in promoting fluidity.

38 ria and that loss of DolP increases membrane fluidity.

39 ion and unsaturated fatty acids for membrane fluidity.

40 stiffness and with high specificity based on fluidity.

41 , organelle dysfunction and altered membrane fluidity.

42 t enzyme that regulates plasma membrane (PM) fluidity.

43 er implications for cell fate and phenotypic fluidity.

44 CI = 69-100), but not on the basis of liver fluidity.

45 sion, likely through an increase in membrane fluidity.

46 rthologs shared by two genomes, (ii) genomic fluidity (a measure of gene content dissimilarity), (iii

47 85), but IGL-1 prevented changes in membrane fluidity after reperfusion when compared with UW (P=0.02

48 pe is characterized by an increase in tissue fluidity akin to a solid-like-to-fluid-like transition.

49 Fluidity and a rigorously maintained spacing result in l

50 iated with slower growth, decreased membrane fluidity and alterations of cell morphology.

51 Cholesterol influences membrane fluidity and assembles lipid-rich microdomains within me

52 e location of the N-terminal helix, membrane fluidity and binding, and the release of lipid modified

53 heir particular structure contributes to the fluidity and biophysical order.

54 s, especially fresh hIAPP, enhanced membrane fluidity and caused losses in cell viability.

55 The correlation between changes in membrane fluidity and cell viability and their lack of correlatio

56 riants determine membrane properties such as fluidity and charge that in turn modulate interactions w

57 the direct result of changes in ER membrane fluidity and composition.

58 ipose tissue represents decreased fatty acid fluidity and could play an important role in the etiolog

59 produced responses suggest that the confined fluidity and curvature constraints imposed on the lipid

60 ter physical properties of the membrane like fluidity and curvature.

61 lization of composite materials that combine fluidity and different forms of ordering at the mesoscop

62 Consequently, cytoplasmic fluidity and dynamics dramatically change as cells shift

63 d on-rate constant, suggesting that membrane fluidity and dynamics may strongly influence bond format

64 Cooling and warming alter membrane fluidity and elicit intracellular free-calcium elevation

65 to the SSLBMs exhibited significant membrane fluidity and have been directed into dimer assemblies on

66 tion significantly reduces cellular membrane fluidity and impairs lipid homeostasis via rate-limiting

67 coli lipid membranes while introducing both fluidity and internal lipid order into the fluid phases.

68 Results revealed a decrease in lipid fluidity and lipid and protein content and also the diff

69 iated with Alzheimer's disease) upon bilayer fluidity and lipid dynamics through the application of v

70 in the pancreatic graft monitoring membrane fluidity and lipid peroxidation.

71 of extracellular matrix results in increased fluidity and loss of structure of the B. subtilis colony

72 At the cellular scale, blood fluidity and mass transport depend on the dynamics of re

73 oduce a bilayer environment of unusually low fluidity and may slow the influx of drugs, contributing

74 sis, indicating a causal association between fluidity and metastasis.

75 iquid-liquid phase separation, regulates the fluidity and mobility of the liquid-like droplets, and f

76 ions, ligand density, lipid charge, membrane fluidity and other molecular details).

77 Materials that combine the properties of fluidity and permanent porosity could therefore offer te

78 owever, the apparent incompatibility between fluidity and permanent porosity makes the stabilization

79 lipase A2alpha (cPLA2alpha) affects membrane fluidity and permeability by catalyzing the hydrolysis o

80 Many Archaea maintain the fluidity and permeability of their membranes by adjustin

81 can modulate membrane properties such as the fluidity and phase separation capability of giant plasma

82 This enables the optical mapping of fluidity and porosity patterns in targeted cellular comp

83 and lipid-rich-and quantify how the membrane fluidity and protein-membrane affinity control the relat

84 AA1 binding also inhibits membrane fluidity and reduces solvent accessibility around the li

85 an important role in maintaining the correct fluidity and rigidity of the plasma membrane of all anim

86 Developmental cues dramatically alter both fluidity and sorting within large RNP assemblies, induci

87 op provides selectivity for sensing membrane fluidity and targeting to defined membrane zones and org

88 ipids, reducing inner mitochondrial membrane fluidity and the mobility of free ubiquinone between com

89 g (FRAP) is widely used to assess condensate fluidity and to estimate protein diffusion coefficients.

90 1 and H2A variants that compromise chromatin fluidity and transcriptional programs within the develop

91 We refer to this property as "crystal fluidity" and suggest that it may be used as an addition

92 l reorganization of the cytoplasm, cytoplasm fluidity, and cellular dormancy.

93 actor determining lipid packing and membrane fluidity, and it must be tightly controlled to guarantee

94 sical properties, including local hydration, fluidity, and lateral lipid packing, usually characteriz

95 report the distinctive lateral organization, fluidity, and lipid domain architecture of protein-free

96 vonoids, antioxidant activity, and increased fluidity, and lower browning index, hue angle, chroma, p

97 depleted of cholesterol had higher membrane fluidity, and more uniform distribution of CD44 counterr

98 tory circuitry, epigenetic memory, cell type fluidity, and reuse of regulatory modules in achieving a

99 for the manipulation of membrane integrity, fluidity, and stability to advance the assisted reproduc

100 urated fatty acids decrease Saureus membrane fluidity, and these altered membrane dynamics are partia

101 brane domains which differ in local membrane fluidity, and which severely disrupts membrane protein o

102 reduced on elongation of the cell, while the fluidity appears to be maintained.

103 hanges in lipid packaging, permeability, and fluidity are appropriate to foresee the potential bioava

104 thered nanotubular porous wicks and enhanced fluidity are the main causes for promoting the CHF incre

105 We envisioned that an increase in crystal fluidity as a function of increasing temperature would f

106 vely, our findings reveal increased membrane fluidity as a necessary cellular feature of metastatic p

107 ation suggests significant changes in genome fluidity as a result of a phase transition affecting the

108 siRNA combined with lipidomics and membrane fluidity assays (FRAP and Laurdan dye staining) we furth

109 n formation, cholesterol influences membrane fluidity, associates with myelin proteins such as myelin

110 h correlates with an increase in mesenchymal fluidity at branch tips that may transport TNC away from

111 d specificity = 85%, 95% CI = 62-100), tumor fluidity (AUC = 0.86, 95% CI = 0.77-0.96; sensitivity =

112 population averages of elastic modulus E and fluidity beta (the power-law exponent of the cell deform

113 the importance of the difference in membrane fluidity between the gel phase DMPC and the liquid cryst

114 stead triggers a rapid reduction of membrane fluidity both in live Bacillus subtilis cells and in mod

115 erent temperatures and analyzed the membrane fluidity by fluorescence anisotropy measurement.

116 blood vessels and function to maintain blood fluidity by producing the protease plasmin that removes

117 Cells maintain membrane fluidity by regulating lipid saturation, but the molecul

118 Tuning the degree of membrane fluidity by tailoring the amount of plasticizing stimulu

119 omponents, and the ability to modulate their fluidity can be critical for the fitness of an ecotype i

120 er-law relationship, the cell elasticity and fluidity can be estimated.

121 isentangling lipid composition from membrane fluidity can be obtained if time resolved spectra could

122 We further demonstrate that fluidity can be regulated by cellular cholesterol flux,

123 Membrane environment and fluidity can modulate the dynamics and interactions of m

124 molecular effects of foreign compounds in SC fluidity can therefore have strong impact on the develop

125 e perturbation of RhoA activity and membrane fluidity, can block this HSS-induced FAK polarity.

126 ew focuses on the architecture of a membrane fluidity communication network; how thermal information

127 m a lamellar phase with a slight increase in fluidity compared to a bilayer without PCB 52.

128 cytoskeleton or the nucleus, elasticity and fluidity data from all treatments collapse onto a master

129 rms, including their characteristic membrane fluidity defects.

130 easurements of mechanics and plasma membrane fluidity demonstrate that changes in actin patterning al

131 m the membrane, leading to enhanced membrane fluidity, disruption of rafts, and impaired antigen-pres

132 eases cholesterol levels, increases membrane fluidity, disrupts lipid rafts, and redistributes CD44,

133 ding spheroid shapes due to surface tension, fluidity due to deformations, and fast internal molecula

134 tion of protein layers with a high degree of fluidity due to the extended conformation of HSA.

135 hese compounds likely help maintain membrane fluidity during dehydration.

136 P-driven events are not a crucial enabler of fluidity during linear viscoelastic deformation of a sus

137 e the effect of chess playing on whole-brain fluidity/dynamism (the chronnectome).

138 Glycine mutations undergo rapid loss of fluidity, emphasizing the role of glycine in promoting f

139 We find that fluidity estimates are consistent in the time and freque

140 e describe adaptations that enhance membrane fluidity; examine genes involved in cellular function an

141 ly unsaturated lipids that increase membrane fluidity, exhibit significantly higher conductance versu

142 chess players exhibited an increased dynamic fluidity, expressed as a higher number of occupied meta-

143 anges in lipid composition decrease membrane fluidity, F(0)F(1)-ATPase activity, and improve intracel

144 of these mechanisms likely regulate membrane fluidity, facilitating the maintenance of efficient phot

145 nd chemical properties and a high dielectric-fluidity factor, the use of electrolytes based on solven

146 ropane fatty acids, (iii) increased membrane fluidity following the initial response of increased rig

147 onset of fluidity reveals a locally enhanced fluidity for bilayer regions supported on nanoporous sil

148 Though the importance of membrane fluidity for cellular function has been well established

149 interface and also decreases plasma membrane fluidity for the enhancement of molecular influx.

150 phy (MRE) to elucidate the role of anomalous fluidity for the invasive growth of soft brain tumors, s

151 ce decay can distinguish changes in membrane fluidity from changes in cholesterol content.

152 lular viscoelastic properties (stiffness and fluidity) from these measurements.

153 We propose a mechanism in which membrane fluidity governs the insertion of PlsX and thus regulate

154 r study suggests that regulation of membrane fluidity has been among the important adaptation process

155 e how both sterols and phospholipids control fluidity homeostasis, we quantified the lipidic composit

156 lotillins are important factors for membrane fluidity homeostasis.

157 Fluidity-hysteresivity normalized to the extremes of an

158 dual nuclei, suggestive of extensive dynamic fluidity in 3D chromatin states.

159 tability in these detergents could be due to fluidity in addition to the already determined structura

160 sts microdomain destabilization and enhanced fluidity in CLN3-null cells.

161 ranes with negative curvature and high lipid fluidity in complex heterogeneous membranes, which confe

162 g chemical structures can alter the membrane fluidity in either direction and correspondingly modulat

163 resulting in a gradual increase in membrane fluidity in individuals ranging from newborn to nonagena

164 Q8 supplementation decreased membrane fluidity in liposomes, but did not affect ProP activity

165 rospectroscopy further indicated lower lipid fluidity in NS cells than in Ctrl and LL cells, potentia

166 receptor action by increasing cell membrane fluidity in postsynaptic neurons.

167 sor protein involved in maintaining membrane fluidity in response to changes in environmental tempera

168 Coexistence of order and fluidity in soft matter often mimics that in biology, al

169 uctures with strikingly different degrees of fluidity in the arrangement of the GJ channel subcompone

170 level such as depth of insertion or membrane fluidity in the CPP vicinity.

171 NA accessibility so as to promote phenotypic fluidity in the response to injury.

172 Overall, these data demonstrate significant fluidity in the T-cell-mediated IL-10 response during vi

173 Recent studies have shown that "crystal fluidity" in the form of fast conformational motions is

174 eases in cell temperature, we establish that fluidity increases with temperature-now measured in a fu

175 hing revealed an increase in plasma membrane fluidity induced by cryptogein, but not by flagellin.

176 eroxidation, resulting in decreased membrane fluidity, intracellular calcium dysregulation, depolariz

177 ation, membrane lipid peroxidation, membrane fluidity, intracellular calcium regulation, passive memb

178 crosecond regime, suggesting that rotational fluidity is 3 orders of magnitude too slow to affect flu

179 In many organisms, regulation of membrane fluidity is crucial for acclimating to variations in tem

180 Fluidity is essential for many biological membrane funct

181 In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid desatura

182 In all cases, the membrane fluidity is maintained, indicating that both cell types

183 Adequate membrane fluidity is required for a variety of key cellular proce

184 ible with ion channel function when membrane fluidity is required.

185 These alterations are reverted when membrane fluidity is restored by a chemical fluidizer.

186 how our understanding of the nature of this fluidity is shaping therapeutic approaches to pancreatic

187 Although fluidity is suppressed by chemical cross-linking, we fin

188 behavioral vigor (i.e., its behavioral speed/fluidity), it remains unclear whether or how these funct

189 apability of CerC16 to modulate the membrane fluidity, its curvature propensity, and the membrane int

190 round each PCB 52 in the bilayer form a high fluidity lamellar phase, whereas lipids beyond these lay

191 for this is the interference of several high fluidity lamellar phases caused by interactions of PCB 5

192 Enhanced-fluidity liquid chromatography (EFLC) involves the addit

193 with phospholipids and sensitivity to lipid fluidity may be sufficient for localization of Hpr and m

194 fluence of MreB on membrane organization and fluidity may explain why the active movement of MreB sti

195 In stem cell lines membrane fluidity may play a role in differentiation.

196 acquisition of this nondimensional property, fluidity may serve as a useful and robust parameter for

197 al change is accompanied by reduced membrane fluidity (measured by infrared ellipsometry).

198 AH domains that alter membrane curvature and fluidity, mediating the scission of constricted membrane

199 ghlights the critical importance of membrane fluidity modulation by desaturases in the adaptive strat

200 receptor partner or capable of mimicking the fluidity of biological membranes have been conceived by

201 a useful parameter to monitor packaging and fluidity of biomembranes.

202 These essential processes enhance fluidity of blood, although accumulating evidence sugges

203 ommon mechanism, the ability to modulate the fluidity of cell membranes.

204 How do cells maintain the fluidity of cellular membrane in response to temperature

205 controls the lipid saturation level and the fluidity of cellular membranes by transcriptionally regu

206 ibit viral entry, possibly by modulating the fluidity of cellular membranes.

207 Our approach is able to account for the fluidity of discursive categories over time, and to anal

208 e addition of a flotillin increases membrane fluidity of liposomes.

209 shape selectivity of porous domains with the fluidity of liquids is a promising one and porous liquid

210 Thus, targeting tissue fluidity of malignant tumors might open horizons for the

211 th in phospholipids facilitate curvature and fluidity of membranes, which favors fusion of membranes.

212 crucially affect the local order, shape, and fluidity of microcolonies.

213 pted from the broader OSATS: motion economy, fluidity of motion, and tissue handling.

214 micking phantoms, we show that the anomalous fluidity of neurotumors physically enables GBMs to penet

215 nces phase separation in vitro and decreases fluidity of phase-separated TDP-43 reporter compartments

216 lipids and fatty acids without altering the fluidity of plasma membranes, indicating that the expres

217 at the interaction likely contributes to the fluidity of RNP droplets.

218 In contrast to the encapsulates increasing fluidity of saturated membranes by disturbing the lipid

219 All solvents investigated cause an increased fluidity of SC lipids, with the most prominent effects s

220 This superflexibility compares with the fluidity of self-assembled liquid bilayers.

221 The fluidity of song composition suggests it provides acoust

222 We find that the fluidity of SYD-2 and ELKS-1 condensates is essential fo

223 ontribute to the viscoelastic properties and fluidity of the bacterial nucleoid to facilitate proper

224 Although long-range lateral fluidity of the bilayer, characterized by fluorescence r

225 generated on mechanical damage, owing to the fluidity of the capillary bridges between nanoparticles

226 iration, metabolism, transcription of genes, fluidity of the cellular wall).

227 The phase characteristics and fluidity of the ER biomimetic was characterized with flu

228 eosome assembly and disassembly and thus the fluidity of the ever-changing chromatin landscape.

229 of reactive oxygen species by modulating the fluidity of the inner mitochondrial membrane.

230 The fluidity of the lipid bilayer expressed as fluorescence

231 tin substrate exerted a direct effect on the fluidity of the lipid membrane and highlighted the fact

232 ursor of cholesterol, resulting in increased fluidity of the membrane where HCV RNA replication occur

233 presence of PsbS leads to an increase in the fluidity of the membrane, accelerating the re-organizati

234 well as macroscopic properties, such as the fluidity of the membrane.

235 smic green fluorescent protein and probe the fluidity of the periplasm as a function of external osmo

236 The plasticity of cancer cells and the fluidity of the tumor microenvironment continue to prese

237 ms) depends on their ability to increase the fluidity of their cellular membranes at low temperatures

238 Bacteria remodel the fluidity of their membrane bilayer precisely via the inc

239 cationic [2]rotaxanes increased not only the fluidity of their smectic A phases but also their therma

240 data modeling challenge, due to the size and fluidity of this resource: each of the 33 cancer types i

241 hloroplasts, was associated with the reduced fluidity of thylakoid membranes, which in turn negativel

242 ify rapid changes in the bending modulus and fluidity of vesicle lipid bilayers on the micrometer sca

243 with deficits in the initiation, speed, and fluidity of voluntary movement.

244 cal stretching, we examine the dependence of fluidity on chemical and environmental influences at a t

245 d to investigate the rules underlying genome fluidity or rigidity, e.g., by comparing marker distance

246 In terms of their size, fluidity, order and lifetime these nanodomains may repre

247 s and a key molecule in controlling membrane fluidity, organization, and other physicochemical parame

248 ive diverse mealybug species and find marked fluidity over evolutionary time.

249 to uncover how modulation of vesicle bilayer fluidity persuades structural transformation.

250 ds, cholesterol, sphingomyelin, and membrane fluidity play critical roles in these processes.

251 lipids and bilayer curvature, while membrane fluidity plays a very minor role.

252 iffer in their soft properties suggests that fluidity plays an important role for a tumor's aggressiv

253 Membrane fluidity plays an important role in many cell functions

254 also showed no relevant effects on membrane fluidity, polarity or partitioning of the spin probe TEM

255 evels of untreated cells, restoring membrane fluidity, preventing the morphological changes, as demon

256 ular strategies to sense changes in membrane fluidity, provoked by a decrease in environmental temper

257 are required for direct control of membrane fluidity rather than for the formation of protein comple

258 sms that include modulation of cell membrane fluidity, regulation of intracellular signaling pathways

259 , whereas fatty acid saturation and membrane fluidity remarkably influence the membrane insertion ste

260 Polymerization yielded BLMs that retain the fluidity required for alamethicin activity yet are stabl

261 s junctions (AJs) provide epithelia with the fluidity required to maintain tissue integrity in the fa

262 ative antimetastasis agents reduced membrane fluidity, resulting in decreased cell motility, stem cel

263 and it was demonstrated, that an increase in fluidity results in a decrease of liposome size as analy

264 afish tailbud and identify changes in tissue fluidity revealed by reductions in the coherence of cell

265 asurements of temperature-dependent onset of fluidity reveals a locally enhanced fluidity for bilayer

266 ate specific membrane regions with increased fluidity (RIFs).

267 enge the prevailing hypothesis that membrane fluidity serves as the measured variable for regulating

268 ssential to brain functions such as membrane fluidity, signal transduction, and cell survival.

269 quid which possesses magnetic properties and fluidity simultaneously.

270 cholesterol content, displaying a profile of fluidity that depends on their intracellular location.

271 f flotillins leads to a decrease in membrane fluidity that in turn leads to alterations in MreB dynam

272 ing and that such disorder favours chromatin fluidity, the structural behaviour and thereby the role/

273 eme and ergosterol depletion alters membrane fluidity, thereby activating Hog1 for hypoxic induction.

274 nt and that lipid bilayer properties such as fluidity, thickness, lateral pressure profile, and charg

275 mechanism to conditionally decrease membrane fluidity through the opposed regulation of FabHa and Fab

276 pted its fatty acid composition and membrane fluidity to a considerably lesser extent when compared w

277 While homeostatic adaptation of membrane fluidity to temperature variation is a ubiquitous featur

278 te the contributions of tissue stiffness and fluidity to the malignancy of liver tumors.

279 displays decreasing stiffness and increasing fluidity toward its posterior elongating region.

280 Overall, our results identify a fluidity transition mediated by loss of cell cohesion as

281 these hybrid, supported membranes undergo a fluidity transition, producing a fully percolating fluid

282 effects of trans-resveratrol on the membrane fluidity using planar lipid bilayer and liposome models.

283 hing experiments and found that mycomembrane fluidity varies widely across species and correlates wit

284 tion of lipid desaturase levels and membrane fluidity via an unprecedented mode of fatty acid signali

285 ors in vitro and in vivo The requirement for fluidity was further supported by the finding in breast

286 Fluidity was higher than the plasma membrane, illustrati

287 nhibited spontaneous metastasis in vivo When fluidity was unchanged, the antimetastasis compounds cou

288 Because tumor cells exhibit altered membrane fluidity, we suggest this might influence pHLIP tumor ta

289 the complex shear modulus reflecting tissue fluidity were abnormally high in malignant tumors and al

290 Four indexes of meta-state dynamic fluidity were studied: i) the number of distinct meta-st

291 tioxidant genes and genes affecting membrane fluidity were up-regulated in both irradiated strains.

292 ical stability and for influence on membrane fluidity, when quercetin and fish oil were encapsulated.

293 a significant increase in genome mobility or fluidity, which facilitates genome release at temperatur

294 es positive curvature and decreases membrane fluidity, which inhibits virus-cell membrane fusion duri

295 refore characterized by a remarkable spatial fluidity, which is likely to impede community-based meth

296 nsis lipids increases B. thailandensis lipid fluidity while preserving internal lipid order.

297 llows for appropriate adjustments in luminal fluidity while reclaiming water used in digesting and ab

298 in cell elastic modulus and decrease in cell fluidity with increasing lamin A levels.

299 eveloped porous material that combine unique fluidity with permanent porosity, which exhibit promisin

300 he most striking results is the evolutionary fluidity with which novel imprinted genes are gained and