ライフサイエンスコーパス: force

1 ne the response of the protein to mechanical force.

2 and live performances of the mental priming force.

3 ch bond strength on the direction of applied force.

4 on channels that are activated by mechanical force.

5 lates that experience transient hydrodynamic forces.

6 SMA) expression, and exerted larger traction forces.

7 termolecular interactions like van der Waals forces.

8 ocol with stepwise increasing and decreasing forces.

9 cur due to internal and external mutagenesis forces.

10 several aspects, especially the influencing forces.

11 coupling of cellular dynamics and mechanical forces.

12 atase exclusion as well as direct mechanical forces.

13 gned to show desired responses to prescribed forces.

14 undred picoNewtons and stiffen at nanoNewton forces.

15 lpies can be attributed to London dispersion forces.

16 ome stretching, suggesting a role in pulling forces.

17 ening to reverse-engineer and identify these forces.

18 etween host-mediated responses and microbial forces.

19 ymes, and electric, mechanical, and magnetic forces.

20 poral and spatial resolution of hydrodynamic forces.

21 ace the cells against external morphogenetic forces.

22 the nonreciprocal interparticle interaction forces.

23 force protocols, such as constant or ramped forces.

24 pulse generator dysfunction, and mechanical forces.

25 anization of cells in response to mechanical forces.

26 lic strain rates, indicating reduced viscous forces.

27 throughout the Common Era, likely via solar forcing.

28 large relative to background variability and forcing.

29 how the ecosystem responds to anthropogenic forcing.

30 deposition alters modeled CCN and radiative forcing.

31 physiologically relevant conditions of lower force (0.3 pN) and lower salt concentration (0.2 M NaCl)

32 nd 480, respectively) with excessive contact force (30 g on average, with peaks up to 50 g).

33 (-46.6%) and ex vivo aortic ring contraction force (-40.1%) were lowered and VSMC actin cytoskeletal

34 nt (median attachment duration >3 s) at high forces (5 pN).

35 he Northern Hemisphere, expanding ice sheets forced a large number of plants, including trees, to ret

36 We then exposed them to either homecage forced abstinence or voluntary abstinence induced by an

37 have used experimenter-imposed extinction or forced abstinence procedures.

38 eking behaviors in animals when given during forced abstinence.

39 Unlike sway minimisation, development of force accuracy was associated with learning and reduced

40 Thus, depending on the geometry of forces across the microtubule, kinesin can switch from a

41 ffers insights into charge-symmetry-breaking forces acting in atomic nuclei.

42 ctional roles and the mosaic of evolutionary forces acting on loci.

43 By quantifying multiple evolutionary forces acting on sPTB-associated regions, our approach i

44 on of cellular force imaging, we developed a force-activatable emitter reporting single-molecular ten

45 stainable food systems, reduction in climate forcing agents, and reduction in wildfires.

46 This greater forcing also contributed to excess loss from the Greenla

47 tretch of the membrane induced by mechanical force alters the physical state of the lipid bilayer, dr

48 g tissue-level functions such as contractile force and be amenable to standard multiwell-plate manipu

49 by DFT calculations, which show the driving force and final structure for the surface metal protrusi

50 effects of acute nitrite infusion on muscle force and skeletal muscle oxidative metabolism.

51 that the distal leg muscles rapidly modulate force and work output to minimize perturbations in uneve

52 series of GMSST over 1950-2010 is externally forced and largely linked to the representation of volca

53 high-speed method for measuring contractile forces and cytosolic calcium dynamics of single muscle f

54 erials that can resiliently tolerate extreme forces and deformation while being manufactured at large

55 been exploited in precision measurements of forces and fundamental constants.

56 T and mutant KSIs provided insights into the forces and interactions that allow and limit active-site

57 rooted in the principled physics of driving forces and reveals granular detail of conformational pop

58 tion leading to the generation of mechanical forces and the deformation of the organ in three dimensi

59 ssions have implications for ozone radiative forcing and possibly new particle formation near the tro

60 of the motors in each filament bear the peak force, and these are confined to the filament domain con

61 associated changes in cell shapes, traction forces, and migration velocities have yet to penetrate.

62 age, coverage, optical properties, radiative forcing, and energy forcing (EF) from individual flights

63 on species composition, local oceanographic forcing, and other pressures from human activities and u

64 the dynamics of unobserved species, external forcing, and the unknown model parameters.

65 Here we use surface force apparatus combined with systematic mutational anal

66 Using a custom developed force apparatus, we demonstrate that chick dorsal root g

67 esence of multivalent ions using the surface force apparatus.

68 Our analysis explains how mechanical force applied to alphaE-catenin or its homolog vinculin

69 Here, we report the effect of force applied to the biaryl backbone of a bisphosphine l

70 inuously measuring the normal and tangential forces applied by the index finger.

71 ts move merely to comply with the mechanical forces applied on macroscopic scales, whereas the molecu

72 aft groups experienced relative cusp closing forces approaching that of the native root, whereas rela

73 2D layers interacting by weak van der Waals forces are currently a hot research topic.

74 In many situations, these forces are exerted or resisted by elastic compliant stru

75 Climatic forcing arose only when susceptible availability was hig

76 ction in molecular vinculin-linked molecular force as well as the downregulation of the Lrp5-CSF1-CD1

77 xfoliation due to the absence of interfacial forces as a nonpolar liquid.

78 mplex, did reverse the loss of diaphragmatic force associated with mechanical ventilation.

79 tresses and fortifies cells to withstand the forces associated with water transport and the physical

80 s; only one finger was instructed to produce force at a time.

81 ld changes in the velocity and the resistive force at which maximum power output occurs.

82 r dilation is possible in response to acting forces at sufficiently fast timescales.

83 of undisturbed sleep (US) and two nights of forced awakening (FA) sleep disruption.

84 the linear folding motions of such sheets to force-bearing modes in conjunction with the Maxwell-Call

85 fore reveal sexual selection as an important force behind lineages facing extinction threats, identif

86 Rather, it forced blood to flow peripherally to the gel.

87 mechanophores to be inert in the absence of force but highly reactive under applied tension.

88 through cell division is a key deterministic force, but identifying inheritance effects in a systemat

89 show that the pause in circulation trends is forced by human activities, and has not occurred owing o

90 A+ molecular machines generate translocating forces by a common mechanism.

91 ial for transduction of innocuous mechanical forces by proprioceptors and cutaneous touch receptors.

92 ing requires the generation of intracellular forces by the cytoskeleton and their transmission to an

93 to achieve both a global search and all-atom force calculations to determine the relative affinities

94 rce-distance relationship, enabling accurate force calibration and force feedback.

95 iotemporal resolution and high dynamic range force capability (10 pN - 100 nN).

96 incoherent attributes such as a construct of force-carrying beams that emanate from the eyes.

97 The resulting electric forces cause the movement of pore water ions in opposite

98 ge, slow responses substantively lag climate forcing, causing disequilibria and reduced fitness, and

99 mouse revealed that decreases in ATP levels force cells into the stationary phase and induce autopha

100 r, the immobilized enzyme recovered by low g-force centrifugation retained 83% of its initial enzymat

101 g into myofibril activation, relaxation, and force changes produced during activation.

102 a standard psychophysical method (2-interval forced choice, in which the participant identifies which

103 ducted a retrospective study of 531 VA-Armed Forces coccidioidomycosis patients diagnosed between 195

104 nectivity driven by stochastic hydroclimatic forcing, conceptualizing wetlands as dynamic habitat nod

105 We apply our method to measure the force dependence of the viscoelastic and plastic propert

106 motors throughout the filament contribute to force development, only about 10% of the motors in each

107 that reinforcement occurs along preferential force directions, thus stabilizing those cytoskeletal fi

108 ng concern to healthcare workers globally as forced displacement and migration from countries with hi

109 the health needs of populations affected by forced displacement; the health systems-level barriers a

110 ibe with only three parameters the induction-force-distance relationship, enabling accurate force cal

111 ns at the cell leading edge, and showed that force distribution in focal adhesions (FAs) is off-cente

112 chromosomes are found in many taxa, but the forces driving their emergence and spread are poorly und

113 s was confirmed intraoperatively by negative forced duction test and the characteristic appearance of

114 ng the role of reflex feedback in regulating force duration in intact muscle.

115 While changes in SWW forcing during the Holocene (i.e., the last ~11,700 y) h

116 re is evidence that individuals have greater force dysmetria but display better temporal accuracy dur

117 al properties, radiative forcing, and energy forcing (EF) from individual flights can be 2 orders of

118 onal pacing, suggesting that direct rainfall forcing effects were predominantly driven by sea-surface

119 relative to the skin) in response to impact forces elicited by walking and running at a range of spe

120 ite revealed only when the probe experiences forces exceeding a defined mechanical threshold (~7-21 p

121 Moreover, it is shown that the viscous drag force exerted by flow on a translocating DNA can be expl

122 full-length protein in the FPA assay to the force exerted by the folding protein in piconewtons.

123 ons precisely represents the impulse vector (force exerted over time) generated by the animal.

124 Andrew Murray argues that you can use your forced exile from the lab to produce better future exper

125 al effects of 474 smoking-associated CpGs on forced expiratory volume in 1 s (FEV(1)) in UK Biobank (

126 etween DHEA-sulfate and percentage predicted forced expiratory volume in 1 s (FEV(1)PP).

127 HSV or T2-weighted VIP were associated with forced expiratory volume in 1 second percentage predicte

128 Airway obstruction was defined as forced expiratory volume in 1-second (FEV1)/forced vital

129 COPD defined by postbronchodilator ratio of forced expired volume in the first second to vital capac

130 Forced expression of the irisin precursor Fndc5 in trans

131 rved in a range of ecosystems due to various forcing factors.

132 hip, enabling accurate force calibration and force feedback.

133 ch we show outperforms the additive CHARMM36 force field in both ion retention and maintenance of the

134 lly without intervention through an external force field or a patterned track.

135 We applied the Drude polarizable force field, which we show outperforms the additive CHAR

136 s of minimization and MD steps, 10 different force fields and three different water models.

137 's new Mission Statement, to be a relentless force for a world of longer, healthier lives, the 2030 I

138 pha-synuclein filaments are the main driving force for amplification and propagation of pathology in

139 However, the major driving force for clearance remains largely unknown.

140 High Plk1 levels were a driving force for different types of spontaneous tumors.

141 While the driving force for the effort is in the realm of nuclear nonproli

142 es that the Gibbs free energy is the driving force for the transformation.

143 collapse in dilute solutions and the driving forces for phase separation in concentrated solutions.

144 es the known equivalence between the driving forces for single-chain collapse in dilute solutions and

145 Both driven and force-free systems are analyzed.

146 rigel) that allows us to measure contractile force from the shape of the relaxed and contracted muscl

147 In accordance with the force-from-filament principle, they may provide a connec

148 mplex with ExbB-ExbD links the proton motive force generated across the inner membrane with energy-de

149 Myosin II is the main force-generating motor during muscle contraction.

150 Furthermore, inhibiting force generation in cancer cells would increase the T ce

151 sion formation, cell spreading, and traction-force generation.

152 tions do not allow intuiting which molecular forces govern the nuclear positioning; we therefore used

153 atibility and ability to generate microscale force gradients.

154 ministic under conditions of relatively high force (>2 pN) and high salt concentration (>0.5 M NaCl).

155 Two subsequent IDSA task forces have emphasized the importance of women, and othe

156 nsitivity and spatial resolution of cellular force imaging, we developed a force-activatable emitter

157 The trial duration, the movement speed, the force impulse after insertion and the endpoint stiffness

158 local selection is an important evolutionary force in natural tree populations and suggest that manag

159 expressing desmin or vimentin generated less force in response to KCl and carbachol relative to the l

160 udy of the decay of the interfacial friction force in rock, observed in experiemntal studies and attr

161 can readily be adapted for studying cellular forces in a wide range of applications.

162 es of tPAINT probes to map integrin receptor forces in live human platelets and mouse embryonic fibro

163 d the terminal mean temporospatial isochrone forces in the RVOT, congruent with the arrhythmogenic su

164 Physiological occlusal force indirectly regulates PDLSCs activities by fine-tun

165 amine muscle oscillation responses to impact forces induced by changes in external interfaces such as

166 ure profile of the EGJ at end-expiration and forced inspiration revealed marked differences between t

167 nciple is to convert a fluctuating, unbiased force into unidirectional motion.

168 y an important role in converting mechanical forces into the sense of touch.

169 This force is almost three orders of magnitude larger than th

170 We propose that striated muscle force is generated by a singular, mesh-like myofibrillar

171 tual environment with haptic feedback of the force is ideally suited to investigating motor learning

172 ut structured poles, the origin of extensive forces is less obvious.

173 nding lines to Northern Hemisphere sea-level forcing is more complicated than previously modelled(1,2

174 n-walled pore at the appressorial base(1-4), forcing it through the leaf cuticle where it elongates i

175 Here, we performed force-ramp and force-jump experiments, in combination with advanced sta

176 While forced labor in the world's fishing fleet has been widel

177 We show that force lengthens kinetochore-fibers by persistently favor

178 l is 7 orders of magnitude faster than brute force MD.

179 for studying such forces, providing spatial force measurements at subcellular resolution.

180 sheet fluorescence microscope with an atomic force microscope (AFM), providing simultaneous volumetri

181 , we highlight the development of the atomic force microscope to investigate interactions with glycan

182 We also provide a deeper focus into atomic force microscopy (AFM) applications that can bridge dive

183 uch as optical and magnetic tweezers, atomic force microscopy (AFM), single-molecule fluorescence res

184 ickness of the deposits acquired from atomic force microscopy (AFM).

185 ess, and imaging were performed using atomic force microscopy (AFM).

186 graphically patterned substrates with atomic force microscopy (AFM).

187 Here we used high-speed atomic force microscopy (HS-AFM) and kinetic modeling which all

188 Traction force microscopy (TFM) has been instrumental for studyin

189 Atomic force microscopy and scanning electron microscopy show c

190 embly pathways obtained using in situ atomic force microscopy are also discussed.

191 of these isoforms were studied using atomic force microscopy at high resolution in air and buffer.

192 tra and surface roughness obtained by atomic force microscopy images.

193 Atomic force microscopy revealed 40-300 nm diameter OMVs from c

194 Atomic force microscopy revealed that MFS CMs are stiffer compa

195 In addition, magnetic force microscopy reveals the ability to tune DMI in a ra

196 Atomic force microscopy reveals the Y269 residue is required fo

197 egrees C in 20 mTorr O(2) is shown by atomic force microscopy to yield nearly pinhole-free film growt

198 oxygen sensing, X-ray scattering, and Atomic Force Microscopy, we show that mammalian pulmonary membr

199 at 5 K, and imaged by high-resolution atomic force microscopy.

200 troscopy mapping and calibrated Kelvin probe force microscopy.

201 d silica wafer was characterized with atomic force microscopy.

202 lus, as measured by a method based on atomic force microscopy.

203 acterized using optical microcopy and atomic force microscopy.

204 responded to the health system challenges of forced migration and refugee-related health including th

205 r tension events and the associated cellular force nanoscopy (CFN).

206 s do not allow H(2)O-diester H-bonding, thus forcing nBA side groups to adapt L-shape conformations,

207 As sarcomeres produce the force necessary for contraction, assessment of sarcomere

208 ctrometers have significant limitations that force nonoptimal modifications to upstream sample prepar

209 We show that stochastic motor force not only enhances diffusion but also leads to size

210 has a large Young's modulus (ca. 26 GPa), a force of 0.1 muN can be generated under one laser spot.

211 The maximum obtained adhesion force of a positively polarized PDA-modified AFM-SECM pr

212 sized beads evoke transient responses at low forces of ~220 nN and pressures of ~5.6 kPa and sustaine

213 f ~5.6 kPa and sustained responses at higher forces of ~360 nN and pressures of ~9.2 kPa.

214 In this context, large-scale forcing of ISM rainfall variability with multi-decadal r

215 Armed forces often rely on strict hierarchical organization, w

216 In 1993, the International Task Force on Disease Eradication classified the political wi

217 Besides, the influence of water shear forces on biofilms is dual.

218 nds existing at any time to sustain the drag forces on the aggregate determines whether it remains in

219 many types of perturbation, including heat, force, osmotic pressure, lipid shortage, and starvation.

220 n mature Tregs, and ex vivo data reveal that forced overexpression of GILZ in mature Tregs inhibits t

221 onse to external mechanical noise and cyclic force perturbations.

222 Furthermore, the proton-motive force (PMF) across the inner-membrane acts at distinct s

223 ng reviews and the evidence update, the task force prioritized several topics for new systematic revi

224 e exploited gramicidin channels as molecular force probes and developed in silico and in vitro assays

225 actin and can quickly rebind, enhancing the force produced by posttetanic twitches, structurally exp

226 gmented nitric oxide (NO) on skeletal muscle force production and oxygen consumption ( VO2 ).

227 This limits force production and promotes muscle relaxation.

228 te by slowing ATP-binding, resulting in high-force production at both homotetramer ends.

229 vidual sarcomeres within a myofibril affects force production.

230 proteins have only been tested using simple force protocols, such as constant or ramped forces.

231 , standardized surveys of the European labor force provide an opportunity to observe mental health co

232 TFM) has been instrumental for studying such forces, providing spatial force measurements at subcellu

233 Here, we performed force-ramp and force-jump experiments, in combination wi

234 ate system to both anthropogenic and natural forcing rather than any intrinsic internal oscillation.

235 performing computationally intensive inverse force reconstruction algorithms.

236 ts in the presence of variable environmental forces remains poorly understood.

237 erns yet its sensitivity to external climate forcing remains uncertain.

238 body was reduced (SLOW condition), the pull-force required to induce a step was less than when the v

239 Limitation to root growth results from forces required to overcome soil resistance to deformati

240 As a control, non-treated forced roots powder (FRP-BE) was tested.

241 dication as "none." Here we revisit the Task Force's assessment in light of developments in typhoid v

242 triboelectrification, the effects of contact force, scan speed, contact cycles, contact region and ch

243 embedded in noise; however, the mechanics of force-sensing proteins have only been tested using simpl

244 Mechanochromism arises from rapid reversible force-sensitive isomerization of STP to a merocyanine, w

245 anical properties of biological samples with force sensitivity and spatial resolution.

246 In endothelial cells, PLXND1 is a direct force sensor and forms a mechanocomplex with neuropilin-

247 otransduction channels have been proposed as force sensors in various physiological processes, such a

248 fixed behavioral system with five orthogonal force sensors, we show for the first time that the activ

249 tance of various ecological and evolutionary forces shaping plant microbiota.

250 d inorganic substrates using single-molecule force spectroscopy (SMFS).

251 In this work, we employ single-molecule force spectroscopy and molecular dynamics simulations to

252 a point for comparison with high-resolution force spectroscopy experiments.

253 7 residues) when examined by single molecule force spectroscopy in vitro displays the properties of a

254 We use magnetic tweezers force spectroscopy to measure changes in extension and m

255 Using single-molecule force spectroscopy, we also define the response of the p

256 eated rice bran protected RP the best during forced storage, with a 35% recovery after 8 weeks.

257 hydrolyzed adsorbates and particle-adhesion forces, suggesting that these species mediate adhesion b

258 We demonstrate that force suppresses depolymerization at both plus and minus

259 time-dependent antidepressant effects in the forced swim and novelty suppressed feeding tests, and in

260 and altered stress-coping strategies in the forced swim task.

261 as liquid chromatography (LC) columns wear, forcing targeted scheduling windows to be much larger th

262 ings show how HGT can act as an evolutionary force that facilitates the spread of nonselected genetic

263 logy is concerned with the health effects of forces that are "above the skin." Although causal infere

264 NMR to further explore the different driving forces that are responsible for these interactions.

265 ation exists that speaks to the evolutionary forces that have shaped the endomembrane system in eukar

266 , a number of factors have shifted that have forced the cardiology community to reconsider the role o

267 eatures of both naive and effector cells has forced the field to struggle with several conceptual que

268 microfluidic device, where the hydrodynamic force then induces precise rotation of the cell inside t

269 lergy and Clinical Immunology created a task force to assess the state of the art and future potentia

270 VSMC adhesion force to FN (+33%) and integrin alpha5 expression were e

271 ermediate is required to generate sufficient force to release a stall induced by the SecM stalling se

272 The data show that S. gordonii binding force to the C. albicans surface is significantly higher

273 during each expiration so that they are not forced to rerecruit during the subsequent inspiration.

274 As a proof of principle, we apply torsional forces to a coarse-grained continuum model of the antibo

275 evious studies have estimated cranial impact forces to be up to 3400 N during ramming, and prior fini

276 collaboration among key committees and task forces to identify and implement pro-inclusion and diver

277 ay was introduced to apply pico-Newton scale forces to lipids and E-cadherin molecules at the living

278 healthy subjects performed accurate cyclical force tracing tasks at 1 Hz by pressing with intermediat

279 at the transformation from motor commands to force trajectories by syringeal muscles functionally cha

280 In polymer mechanochemistry, a mechanical force, transduced along polymer chains, is used to activ

281 n remained in its normal position within the force transduction layer.

282 Flow-dependent force transfer required talin's C-terminal actin binding

283 riteria of the U.S. Preventive Services Task Force (USPSTF) for annual CT lung screening were analyse

284 including the U.S. Preventive Services Task Force (USPSTF), recommend a range of clinical preventive

285 forced expiratory volume in 1-second (FEV1)/forced vital capacity (FVC) ratio <0.7.

286 oved patients' HRCT scan scores (P < .0001), forced vital capacity (P = .0017), FEV(1) (P = .037), an

287 or carbon monoxide, total lung capacity, and forced vital capacity (rho = -0.76, -0.70, and -0.62, re

288 Force volume AFM can precisely capture the mechanical pr

289 imers due to hydrogen bonding and dispersion forces was observed as well.

290 thorax epithelium responds to morphogenetic forces, we found that the number of apical stress fibers

291 No differences in force were observed between conditions.

292 ng that of the native root, whereas relative forces were >5-fold higher in the anticommissural plicat

293 3D electrodes to produce a dielectrophoretic force which traps cells inside the capturing chambers of

294 ed cycle-by-cycle fluctuations in mechanical forces which vary considerably with pathology.

295 nical states with different sensitivities to force, which we name "young/strong" and "old/weak." The

296 rotect chromosome attachments from transient forces while allowing spindle remodeling, and chromosome

297 tions of the application of these mechanical forces will provide insights into physiology and pathoph

298 ropose that basin-impact-generated hurricane-force winds created sediment-laden atmospheric condition

299 FAC as 'change (POST-PRE) in correlation of force with position' and SC as 'change in sway'.

300 empt to produce three discrete hand grasping forces with the dominant hand.