ライフサイエンスコーパス: forward reaction

1 has only a minimal effect on the rate of the forward reaction.

2 O-galactosides, almost as efficiently as the forward reaction.

3 dicating that it does not have a role in the forward reaction.

4 e for the reverse reaction than that for the forward reaction.

5 se reaction, despite poor utilization in the forward reaction.

6 formed at pH 8, which is the optimum for the forward reaction.

7 ion cannot increase further, neither can the forward reaction.

8 ation of the collision complex limiting each forward reaction.

9 licated AMP release as rate-limiting for the forward reaction.

10 her verified a random Bi Bi mechanism in the forward reaction.

11 ate constant 3300 times smaller than for the forward reaction.

12 hiol and disulfide groups, thus favoring the forward reaction.

13 s preferentially folded at the moment of the forward reaction.

14 f 1.2 on V and 1.7 on V/K(homoserine) on the forward reaction.

15 G smaller for the back reaction than for the forward reaction.

16 s smaller for the back reaction than for the forward reaction.

17 en the stereoselectivity of the back and the forward reactions.

18 gy species or the energy lost in driving the forward reactions.

19 BuSH, in agreement with the results from the forward reactions.

20 ps during Na(+)-Na(+) exchange while slowing forward reactions.

21 e rate constant of the chemical step for the forward reaction (250 s(-)(1)) is approximately 8 times

22 the reverse of the physiologically important forward reaction; (3) acetoacetate decarboxylation to fo

23 th a rate constant of about 2400 s-1 for the forward reaction and 230 s-1 for the back reaction.

24 mately 0.6 kcal/mol of stabilization for the forward reaction and approximately 2.2 kcal/mol of desta

25 oredox reactions for which the rates for the forward reaction and back electron transfer are competit

26 controllable local-heating mechanism for the forward reaction and catalyzed by a single charge-transf

27 s kinase is uniquely specific for GTP in the forward reaction and GDP in the reverse reaction.

28 er network can have on the energetics of the forward reaction and how metals or enzyme side chains ma

29 harnesses negative supercoiling to drive the forward reaction and promote recombination between prope

30 The salt dependence of the forward reaction and the similarities of the on-rates of

31 t for K165Q was decreased only 2-fold in the forward reaction and was slightly increased in the rever

32 -0.23 +/- 0.03 cm(3) mol(-1) MPa(-1) for the forward reaction, and k(r,0) = 20.7 +/- 0.8 s(-1), Delta

33 H(2)O + HF (81%) is identical to that of the forward reaction, and represents a novel neutral-catalyz

34 rect nucleotide commits the substrate to the forward reaction, and the slow reversal of the conformat

35 ts of a steady-state kinetic analysis of the forward reaction are diagnostic for a ternary complex me

36 stress response, but characteristics of the forward reaction are not known.

37 phosphoribosyl transfer step was fast in the forward reaction, as observed with the wild type.

38 rted to substrate (ATP) concentration in the forward reaction assay by using an ex-situ calibration c

39 uccinyl-CoA, the N150F variant catalyzes the forward reaction at a mere 1.2-fold faster rate than tha

40 ding a larger k(cat) compared to that of the forward reaction ATP + AMP --> 2ADP.

41 temperature-dependent kinetic studies on the forward reaction between dioxygen and [Cu(I)(tmpa)(thf)]

42 e rate constant for the chemical step of the forward reaction by a factor of 15 and the rate constant

43 rface carbonic anhydrase should catalyze the forward reaction CO 2 +OH - ->HCO 3- if HCO 3- is the su

44 oribosylamine examined as substrates for the forward reaction consist of chiral derivatives of cyclop

45 to be significantly higher than that for the forward reaction, consistent with kinetic activity measu

46 The forward reaction (consumption of maltose) is specific fo

47 s, in which a single chemical reaction (the "forward" reaction) converts a conformationally unstable

48 in binding pocket, the reaction rates of the forward reaction differ quite largely from a few ps up t

49 apid equilibrium prior to l-glutamate in the forward reaction direction.

50 A new continuous assay for the forward reaction, employing cystathionine beta-lyase and

51 s (lox66 and lox71) that display a favorable forward reaction equilibrium.

52 Exchange against forward reaction flux (PAPS plus naphthol) beginning wit

53 Second, the switch is bilabile with the forward reaction following an association-activated inte

54 roduct inhibition studies indicated that the forward reaction follows a random Bi Bi mechanism.

55 turnover numbers (kcat) were 394 s-1 for the forward reaction (formation of ADP and GDP) and 90 s-1 f

56 Stopped flow fluorimetry for the forward reaction gave a saturable fluorescence quench wh

57 sequential ordered kinetic mechanism for the forward reaction in which ATP binds to free enzyme, foll

58 In the forward reaction, in which a base (hypoxanthine or guani

59 A mechanism is presented for the forward reaction, in which Asp74 and Glu98 together gene

60 In the forward reaction (indoline + L-Ser) to synthesize DIT, t

61 is to create a reaction cycle, in which the forward reaction is driven by a chemical fuel and the ba

62 For several systems, the forward reaction is exergonic and the corresponding reac

63 The forward reaction is found to proceed through the second

64 Our previous studies showed that the forward reaction is gated by a rearrangement of the dipr

65 mechanics (QM/MM) analysis suggests that the forward reaction is mainly a nucleophilic substitution o

66 The forward reaction is more sensitive to denticity (bidenta

67 (by malonate), whereas ROS production in the forward reaction is prevented by malonate but not by atp

68 lization of guanine than hypoxanthine in the forward reaction is the result of the faster release of

69 DNA synthesis (forward reaction) is "balanced," as dictated by the chem

70 XPRTase with respect to both guanine (in the forward reaction; Ki = 13 microM) and GMP (in the revers

71 ch is equivalent to reducing the rate of the forward reaction leading to film growth, the other analo

72 several activities include: polyP synthesis (forward reaction), nATP --> polyP(n) + nADP (Equation 1)

73 rast, in the quasi-stochastic mechanism, the forward reaction occurs quasi-stochastically in an unfol

74 tivity of NDPK, F(1)F(0) ATP synthase or the forward reaction of adenylate kinase could not fully acc

75 Although the steps for the forward reaction of ATP hydrolysis by the motor protein

76 In terms of the forward reaction of CO(2)(aq) with amine, the order with

77 n of autophagy is controlled not only by the forward reaction of generating PI3P through a lipid kina

78 The forward reaction of nicotinamide nucleotide transhydroge

79 The forward reaction of NNT, a nuclear-encoded mitochondrial

80 0% for the primary isomerization step in the forward reaction of NpR6012g4.

81 0 and Hsp70, suggesting that CHIP blocks the forward reaction of the Hsc70-Hsp70 substrate-binding cy

82 icate CHIP in the negative regulation of the forward reaction of the Hsc70-Hsp70 substrate-binding cy

83 k(obs,m) and k(obs,f) represent the native, forward reaction of the substrate through the radical re

84 nders this step nearly rate-limiting for the forward reaction of TpCS.

85 (3-fold) change in the photokinetics of the forward reaction over the fluorotyrosine series.

86 nstant for any other first-order step in the forward reaction pathway.

87 that precedes XMP and enzyme release in the forward reaction pathway.

88 For all five redox systems, the forward reaction peak current varied linearly with the s

89 of GTP from GDP, is 75-fold greater than the forward reaction, poly P synthesis from GTP.

90 Whereas the kinetics for the forward reaction (Pr-to-Pfr) was nearly identical for bo

91 hus, D185 appears to participate only in the forward reaction, probably required for the generation o

92 AK exhibits a 23- +/- 3-fold increase in its forward reaction rate compared with the unactivated form

93 We show that the second-order forward reaction rate constant (k(on)) depends on both l

94 on, we have now measured the creatine kinase forward reaction rate constant in BD.

95 d a significant reduction in creatine kinase forward reaction rate constant in the BD group (F = 4.69

96 cipants at 4T and quantified creatine kinase forward reaction rate constant using (31)P magnetization

97 The forward reaction rate constants of these two reactions w

98 e varied without significantly affecting the forward reaction rate.

99 catalytic rates in both cases by increasing forward reaction rates of ES and EP(i).

100 placement reactions whilst barely perturbing forward reaction rates: the introduction of mismatches w

101 etition between charge recombination and the forward reactions required for water splitting limits th

102 Pre-steady-state kinetic analysis of the forward reaction revealed a burst in product formation i

103 +/- 4 J mol(-1) K(-1), respectively, for the forward reaction (rhomboid to hexagon) of the equilibriu

104 ase of a correct substrate commits it to the forward reaction so that specificity is determined solel

105 self-organizing, acetylation-dependent feed-forward reaction that enables long-range interactions by

106 ntermediate clusters in competition with the forward reactions that grow the clusters into particles.

107 all plastocyanin variants is faster than the forward reaction, the difference in free energy between

108 physiological concentrations (10 mM) in the forward reaction, they were poor inhibitors even at high

109 ing the response to it either by slowing the forward reaction through mutation or by titration of the

110 ate carboxylase have been determined for the forward reaction to form oxaloacetate, the reverse react

111 elatively higher catalytic efficiency in the forward reaction to the unusual loop structure for poor

112 The relative rates of forward reaction versus dissociation from the DNA, and t

113 The steady-state rate in the forward reaction was preceded by a burst (nfwd = 1.5/dim

114 Patterns of product inhibition of the forward reaction were consistent with a version of the i

115 Forward reactions were defined by time courses of biphas

116 45 is positioned to serve as the base in the forward reaction whereas the carboxylate side chain of G

117 143 microm with a k(cat) of 2.8 s(-1) in the forward reaction, whereas AMP and PP(i) have K(m) values

118 to hAPRT is substrate shape-specific in the forward reaction, whereas it is base-specific in the rev

119 he relative catalytic efficiencies favor the forward reaction, which can be attributed to an unusuall

120 lBCAT3 and -4 exhibited a preference for the forward reaction, while SlBCAT1 and -2 were more active

121 This change leads to increased kcats for the forward reactions with guanine and xanthine as substrate

122 Complex II generates these ROS in both the forward reaction, with electrons supplied by succinate,

123 ion by univalent cations was observed in the forward reaction, with NH+4, Rb+ and K+ exerting the gre

124 Much is known about the linear forward reactions within platelet signalling pathways bu