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1 rostructural integrity (mean diffusivity and fractional anisotropy).
2 ffects (deletion > control > duplication) on fractional anisotropy.
3 rebrospinal fluid were associated with lower fractional anisotropy.
4 gray matter volume, hippocampal volume, and fractional anisotropy.
5 ec vs [0.9 +/- 0.09] x 10(-3) mm(2)/sec), or fractional anisotropy (0.43 +/- 0.05 vs 0.42 +/- 0.06).
6 95% confidence interval, -25.1 to -2.2) and fractional anisotropy (-0.0073; 95% confidence interval,
7 r in patients with Fabry disease had reduced fractional anisotropy [0.422 (SD 0.022) versus 0.443 (SD
9 genual structures, with frontal white matter fractional anisotropy abnormalities partially encircling
10 ion, female patients had significantly lower fractional anisotropy across all tracts compared with fe
11 r agreement between diffusion tensor imaging fractional anisotropy across the brain in an individual
13 ruption in interhemispheric circuitry (i.e., fractional anisotropy alterations in the corpus callosum
16 entify: (i) the relationships between median fractional anisotropy and apathy, depression and cogniti
17 onvolution-based tractography indicated that fractional anisotropy and apparent fiber density in trac
19 increasing age was associated with increased fractional anisotropy and decreased apparent diffusion c
20 tiple regression analyses revealed decreased fractional anisotropy and decreased axial diffusivity wi
24 group demonstrated lower CC integrity (lower fractional anisotropy and higher mean diffusivity) and p
25 3 months post-optic neuritis predicted lower fractional anisotropy and higher radial diffusivity at 1
27 schizophrenia patients tended to have lower fractional anisotropy and lower IQ than healthy particip
28 ne (Val) and Val/Val genotypes showed higher fractional anisotropy and lower radial diffusivity durin
29 ish immersion program correlated with higher fractional anisotropy and lower radial diffusivity in th
30 ve symptoms and white matter microstructure (fractional anisotropy and mean diffusivity [MD]) in the
31 fasciculus, and cingulum was assessed using fractional anisotropy and mean diffusivity and analyzed
33 tics was used to derive skeletonized maps of fractional anisotropy and mean diffusivity for each part
34 also observed limited change in white matter fractional anisotropy and mean diffusivity in 13 players
35 ed that the diffusion abnormalities for both fractional anisotropy and mean diffusivity were anatomic
40 s of white matter microstructural integrity (fractional anisotropy and mean diffusivity) and cerebrov
43 ied using tractography to derive measures of fractional anisotropy and mean, axial, and radial diffus
45 f diffusion tensor metrics showed widespread fractional anisotropy and radial diffusivity differences
46 pattern of ischemic brain injury (increased fractional anisotropy and reduced radial diffusivity).
47 t with diffusion tensor imaging by measuring fractional anisotropy and the apparent diffusion coeffic
49 ed abnormal age-related changes with greater fractional anisotropy and volume than normal at younger
51 wed the most significant correlation between fractional anisotropy and white matter longitudinal atro
52 age-independent negative association between fractional anisotropy and years since most severe blast
53 , we examined the microstructure (indexed by fractional anisotropy) and volume of axon pathways using
54 l measures (free-water (FW) and FW-corrected fractional anisotropy), and functional connectivity of t
57 FPN (i.e., gray matter volume, white matter fractional anisotropy, and intra/internetwork functional
58 using regional grey and white matter volume, fractional anisotropy, and mean diffusivity (MD) analyse
59 tween regional WM structures (WM volume, and fractional anisotropy, and mean diffusivity [MD]), and f
61 bjects with calculation of mean diffusivity, fractional anisotropy, and sheetlet orientation (seconda
62 rity of damage within these connections, (i) fractional anisotropy as a measure for integrity; (ii) t
65 e influence of age on gray matter volume and fractional anisotropy at a whole-brain and voxel level.
66 of diffuse axonal injury, with reductions of fractional anisotropy at baseline and follow-up in large
67 sess white matter integrity, with indices of fractional anisotropy, axial diffusivity, and radial dif
68 ers of brain microstructural integrity (i.e. fractional anisotropy, axial, mean and radial diffusivit
69 -0.17 to -0.03 cm3; P = .006), lower global fractional anisotropy (b = -0.12; 95% CI, -0.24 to -0.01
70 remor relief in ET was associated with lower fractional anisotropy before treatment (R = -0.5; P = .0
71 HCC was associated with higher left amygdala fractional anisotropy (beta = 0.677, p=0.010), lower lef
74 ime had a slower developmental trajectory of fractional anisotropy compared with individuals whose au
75 rrying the T (risk) allele showing decreased fractional anisotropy compared with other subgroups, ind
76 analysis was used to calculate both a global fractional anisotropy component (gFA) and a fractional a
77 fractional anisotropy component (gFA) and a fractional anisotropy component for six long association
81 er, in participants with multiple sclerosis, fractional anisotropy decreased and mean diffusivity of
82 10-14) as well as a significant whole-brain fractional anisotropy deficit (Cohen d = 0.63; P = 2.20
83 ith the severity of schizophrenia-associated fractional anisotropy deficits in the corresponding whit
84 zophrenia only after age 35, and the rate of fractional anisotropy deterioration with age was constan
85 he diffusion biomarkers mean diffusivity and fractional anisotropy effectively discriminate CA from h
87 al diffusivities (RD/AD = 0.40 +/- 0.02) and fractional anisotropy (FA = 0.53 +/- 0.01) differentiate
88 lobal white matter integrity, as measured by fractional anisotropy (FA) (beta = -0.182, p = 0.005).
91 , whole brain voxel-wise regressions between fractional anisotropy (FA) and ADHD composite score were
93 gions, normative percentiles of variation in fractional anisotropy (FA) and cortical thickness (CT) w
94 M) volume, white matter (WM) microstructure (fractional anisotropy (FA) and diffusivity), white matte
95 hosis risk symptoms had lower whole-brain WM fractional anisotropy (FA) and higher radial diffusivity
96 ract-specific microstructure was assessed by fractional anisotropy (FA) and mean diffusivity (MD) by
98 e obtained at child's 9-12 years of age, and fractional anisotropy (FA) and mean diffusivity (MD) wer
99 assessed white matter integrity measured by fractional anisotropy (FA) and mean diffusivity (MD) wit
102 ysis by determination of helical angle (HA), fractional anisotropy (FA) and myocardial disarray index
105 brain white matter microstructure indexed by fractional anisotropy (FA) and three broad cognitive dom
106 imes through age 4 months; diffusivities and fractional anisotropy (FA) assessed in 7 white matter tr
108 s as demonstrated by widespread reduction in fractional anisotropy (FA) based on diffusion-weighted i
109 ted up to 2014 to identify studies comparing fractional anisotropy (FA) between patients and control
110 ale participants were evaluated for seasonal fractional anisotropy (FA) changes in specific WM tracts
111 perform voxel-wise statistical comparison of fractional anisotropy (FA) data and computational morpho
112 Over the 2.0-year follow-up interval, global fractional anisotropy (FA) decreased by 0.0042 (P < .001
115 White matter integrity was measured with fractional anisotropy (FA) from diffusion tensor magneti
116 We observed subtle, but widespread, lower fractional anisotropy (FA) in adult MDD patients compare
119 und increased cortical volumes and decreased fractional anisotropy (FA) in SAD compared with healthy
121 ia and frontoparietal network with decreased fractional anisotropy (FA) in the right hemisphere and a
122 white matter organization measured by lower fractional anisotropy (FA) in the tapetum region of the
123 t SLF structural connectivity as measured by fractional anisotropy (FA) in the Tenacity group only.
124 the temporal lobes and corpus callosum, and fractional anisotropy (FA) index measurement of the corp
128 using functional magnetic resonance imaging, fractional anisotropy (FA) of diffusion tensor imaging,
130 ze groups that show a critical difference in fractional anisotropy (FA) of the left and right cingulu
133 diffusion tensor imaging (DTI) studies used fractional anisotropy (FA) to investigate disrupted whit
134 s, and cognition with cortical thickness and fractional anisotropy (FA) using general linear models.
135 conduct genome-wide association analysis of fractional anisotropy (FA) value measured using diffusin
136 efore gene therapy revealed lower total mean fractional anisotropy (FA) values in patients than in th
137 nitive Battery (MCCB) and the voxel-wised WM fractional anisotropy (FA) values were examined using DT
139 e values lower than controls (p < 0.05), and fractional anisotropy (FA) was lower within the left unc
141 ellar peduncle and frontal white matter) and fractional anisotropy (FA) was used to compute an FA sco
142 Within-subject measures of STN volume and fractional anisotropy (FA) were derived from high-resolu
145 al changes of cortical mean kurtosis (MK) or fractional anisotropy (FA) were heterogeneous across the
148 in adults with anxiety disorders, decreased fractional anisotropy (FA), a measure of white matter in
150 ed white matter trajectories, as measured by fractional anisotropy (FA), across the course of schizop
151 thickness, subcortical volume, white matter fractional anisotropy (FA), and behavioral measures in 1
152 cross-sectional area (CSA), lateral funiculi fractional anisotropy (FA), and brain GM volume as indep
153 (FFs), T2 relaxation of muscle (T2(water)), fractional anisotropy (FA), and diffusivity (mean, axial
154 regional volumes, global and tract-specific fractional anisotropy (FA), and global mean diffusivity
155 atistics were used to investigate changes in fractional anisotropy (FA), axial diffusivity (AD) and r
156 ing diffusion tensor imaging (DTI) measures: fractional anisotropy (FA), axial diffusivity (AD), and
157 myelin water fraction (MWF), T1w/T2w ratio, fractional anisotropy (FA), axial diffusivity (AD), radi
158 I with apparent diffusion coefficient (ADC), fractional anisotropy (FA), fiber number (FN) and cerebr
159 ow cell, collagen and elastin content effect fractional anisotropy (FA), mean diffusivity (MD) and tr
160 ffusivity (AD) without significant change in fractional anisotropy (FA), mean diffusivity (MD) or rad
161 imaging (n = 300), we compared white matter fractional anisotropy (FA), mean diffusivity (MD), and f
163 data were acquired and analyzed in terms of fractional anisotropy (FA), mean diffusivity (MD), radia
168 tatistics analytic pipeline to first analyze fractional anisotropy (FA), the most commonly employed m
169 er total gray matter volume and lower global fractional anisotropy (FA), whereas maternal depressive
172 OCD < CONT; F([1,87]) = 5.3; P = 0.024) upon fractional anisotropy (FA, a measure of fiber collineari
173 m damage was found in the ablated core (mean fractional anisotropy [FA] at baseline, 0.41 +/- 0.10, a
174 atter tracts, and microstructural integrity (fractional anisotropy, FA) was assessed using tract-base
175 er volume, and white matter tract integrity (fractional anisotropy, FA) within brain regions implicat
176 lume and thickness, and mean diffusivity and fractional anisotropy from co-registered diffusion maps
177 cerebral white matter damage as evaluated by fractional anisotropy from diffusion tensor MRI schedule
181 -frontal pathway; weaker connectivity (lower fractional anisotropy, higher mean diffusivity) was asso
183 arger visual cortex effects also had reduced fractional anisotropy in an anterior portion of the left
184 he tract segment [P </= .0001] and increased fractional anisotropy in approximately 16% of the tract
185 n index (beta = -0.597, p=0.034), and higher fractional anisotropy in connections between the right a
188 Treatment responders demonstrated greater fractional anisotropy in left thalamocortical, limbic, a
189 found a negative relation between AT and UF fractional anisotropy in male but not female monkeys (AT
190 D) in the ventral thalamus and a decrease in fractional anisotropy in optic nerve and optic tract in
192 er was associated with significantly reduced fractional anisotropy in regions that included frontal l
193 arpal tunnel syndrome demonstrated increased fractional anisotropy in several regions and, for these
194 in frontolimbic regions at rest and reduced fractional anisotropy in several white matter tracts.
195 ren were found to have slower development of fractional anisotropy in the cingulum bundle, superior l
196 = 34,194), 2) basal ganglia volumes, and 3) fractional anisotropy in the corpus callosum and corona
197 oral epilepsies had pronounced reductions in fractional anisotropy in the corpus callosum, corona rad
198 and nonimpaired groups in the association of fractional anisotropy in the forceps major with number o
199 Higher widespread white matter FW and lower fractional anisotropy in the fornix showed a stronger as
202 cts, ever smoked was associated with reduced fractional anisotropy in the left cingulate gyrus part o
204 tract, and a correlation between preablation fractional anisotropy in the motor thalamus and clinical
205 ulcal regions with a significant decrease in fractional anisotropy in the patient group compared to c
206 rtate ratio in the thalamus and in preserved fractional anisotropy in the posterior limb of the inter
207 h structural connectivity as measured by the fractional anisotropy in the white matter underlying the
208 -65 and glutamine synthetase in PFC; reduced fractional anisotropy in various brain regions revealed
209 sue volumes and white matter microstructure (fractional anisotropy) in 134 PLWH receiving suppressive
210 res reflecting neuroanatomical connectivity (fractional anisotropy) in 77 children [40 controls (20 f
212 tial statistics showed a marked reduction of fractional anisotropy, increase of radial diffusivity (P
214 icant regional gray matter volume decreases, fractional anisotropy increases, and mean diffusivity de
215 resonance imaging in awake mice showed that fractional anisotropy is reduced in Plp-Nf1 (fl/+) corpu
218 ric mean ratio 1.09, 95% CI 0.90 to 1.32) or fractional anisotropy (mean difference -0.01, 95% CI -0.
219 95% CI: 0.051, 0.129; P < .001), with lower fractional anisotropy (mean difference in z score per st
222 , and diffusion tensor imaging metrics, i.e. fractional anisotropy, mean, axial and radial diffusivit
224 white matter hyperintensities (N = 42,310), fractional anisotropy (N = 17,663) and mean diffusivity
225 rve latency was associated with reduction of fractional anisotropy near (i) contralesional hand area
226 ing finger tapping rate (p = 0.027), whereas fractional anisotropy of aMF originating in the contrale
229 tal-motor cortex FC, accompanied by a higher fractional anisotropy of left corona radiata, predicted
231 volume of the visual association cortex and fractional anisotropy of pontine white matter pathways w
233 (P = 8.8 x 10(-7)) negative association with fractional anisotropy of the forceps major (effect size
237 fusion tensor imaging analysis revealed that fractional anisotropy of the right cingulum was inversel
238 culus to h2 = 0.46 (SE, 0.15; P = .0009) for fractional anisotropy of the right inferior fronto-occip
240 call test) improved significantly; increased fractional anisotropy of white matter (a measure of cere
241 = 0.015)] and white matter changes including fractional anisotropy of white matter (DeltaR2 = 0.417,
242 correlated negatively with the mean general fractional anisotropy of white matter tracts exclusively
243 d N-acetylaspartate (NAA)/choline (Cho), and fractional anisotropy of white-matter pathways was asses
244 than previously used diffusion MRI metrics (fractional anisotropy or fiber-tracking recovered stream
247 rsion (P < 0.001 by paired t-test) and lower fractional anisotropy (P < 0.001 by related-samples Wilc
248 an 16% reduction of spinal cord white matter fractional anisotropy (P </= 0.0003) with a concomitant
249 the frontostriatal tract at follow-up: lower fractional anisotropy (p=0.069), higher axial diffusivit
250 The left arcuate fasciculus had decreased fractional anisotropy, particularly near the anterior no
251 njury predicted the degree of brain atrophy: fractional anisotropy predicted progressive atrophy in b
254 structural network efficiency and cognition (fractional anisotropy: r = 0.329 and r = 0.447 number of
255 -weighted imaging (to derive optic radiation fractional anisotropy, radial diffusivity, and axial dif
256 on tensor imaging metrics (mean diffusivity, fractional anisotropy, radial diffusivity, axial diffusi
257 ted faster brain development in white matter fractional anisotropy (rate of increase, 2.2%; 95% CI, 0
258 Results Mean diffusivity was elevated and fractional anisotropy reduced in CA compared with both c
259 who stutter exhibited significantly reduced fractional anisotropy relative to controls in white matt
260 s, the more anxious twin exhibited decreased fractional anisotropy (t = -2.22, p = 0.032) and axial d
262 free-water and altered free-water corrected fractional anisotropy that included the basal ganglia, t
263 white matter (white matter hyperintensities, fractional anisotropy [theoretical range, 0 {diffusion i
266 howed a significant association pathway from fractional anisotropy to processing speed to working mem
267 etween head impact exposure and change of FA fractional anisotropy value of whole, core, and terminal
268 he age-, sex-, and site-adjusted mean global fractional anisotropy value was 3.8% higher (95% CI, 1.1
269 Spatial Statistics analysis revealed higher fractional anisotropy values for bilinguals vs. monoling
270 The severity of neglect correlated with fractional anisotropy values in superior longitudinal fa
271 l precentral gyri positively correlated with fractional anisotropy values of the CC subregion III, wh
273 Compared with controls, free-water-corrected fractional anisotropy values were increased for multiple
274 f white matter pathways, as indexed by lower fractional anisotropy values, uniquely within the pons.
276 of injury severity and microbleeds (>50% for fractional anisotropy versus <5% for other measures).
277 whereas in the short-range connections only fractional anisotropy was affected (z = -0.34, P = 0.03)
280 extracellular volume (r=0.68, P=0.004), and fractional anisotropy was inversely correlated with circ
281 ility analyses revealed that variation in UF fractional anisotropy was largely due to nonheritable fa
282 althy controls the mean average white matter fractional anisotropy was lower in [0.423 (standard devi
290 -group differences in gray matter volume and fractional anisotropy were regionally localized across t
291 rates of reduction of gray matter volume and fractional anisotropy were significantly faster in males
292 sonance imaging and diffusion tensor imaging fractional anisotropy were used to measure functional co
293 -brain and regional diffusion tensor imaging fractional anisotropy were used to measure white matter
294 e deletion group showed widespread increased fractional anisotropy when compared with duplication.
297 ostructure were also seen, including reduced fractional anisotropy with increased mean and radial dif
299 Moreover, age-associated differences in fractional anisotropy within these tracts were comparabl
300 connections showed the largest reduction in fractional anisotropy (z = -1.03, P < 0.001) and total n